Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_D22
(812 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P40529|AGE2_YEAST Protein AGE2 117 5e-26
sp|Q96P47|CENG3_HUMAN Centaurin-gamma 3 106 9e-23
sp|Q96P50|CENB5_HUMAN Centaurin-beta 5 (Cnt-b5) 104 3e-22
sp|Q8BXK8|CENG2_MOUSE Centaurin-gamma 2 (ARF-GAP with GTP-b... 104 3e-22
sp|Q9UPQ3|CENG2_HUMAN Centaurin-gamma 2 (ARF-GAP with GTP-b... 103 6e-22
sp|Q15057|CENB2_HUMAN Centaurin-beta 2 (Cnt-b2) 102 1e-21
sp|Q9NGC3|CEG1A_DROME Centaurin-gamma 1A 102 2e-21
sp|Q15027|CENB1_HUMAN Centaurin-beta 1 (Cnt-b1) 100 5e-21
sp|O75689|CENA1_HUMAN Centaurin-alpha 1 (Putative MAPK-acti... 99 2e-20
sp|O74345|UCP3_SCHPO UBA-domain containing protein 3 98 2e-20
>sp|P40529|AGE2_YEAST Protein AGE2
Length = 298
Score = 117 bits (292), Expect = 5e-26
Identities = 56/113 (49%), Positives = 83/113 (73%), Gaps = 4/113 (3%)
Frame = +3
Query: 27 LAELLKDDDNKYCVDCDSK-GPRWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWT 203
L+ LL+D N +C DC ++ PRWASW+LG+F+CI+CAGIHR+LG H+S+VKSV+LD+W
Sbjct: 11 LSALLRDPGNSHCADCKAQLHPRWASWSLGVFICIKCAGIHRSLGTHISKVKSVDLDTWK 70
Query: 204 PQQVAMMKEIGNS-RGRAIYEANLEDNFR-RPQTD-SSLEQFIRSKYEHKRYI 353
+ + + + N+ R + YEA L D + R TD SSL+ FI++KYE+K++I
Sbjct: 71 EEHLVKLIQFKNNLRANSYYEATLADELKQRKITDTSSLQNFIKNKYEYKKWI 123
>sp|Q96P47|CENG3_HUMAN Centaurin-gamma 3
Length = 876
Score = 106 bits (264), Expect = 9e-23
Identities = 50/116 (43%), Positives = 76/116 (65%), Gaps = 3/116 (2%)
Frame = +3
Query: 54 NKYCVDCDSKGPRWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEI 233
N +C+DCD+ P WAS LG +CI C+GIHR+LG HLSRV+S++LD W P+ +A+M +
Sbjct: 639 NSFCIDCDAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDLDDWPPELLAVMTAM 698
Query: 234 GNSRGRAIYEANLEDNFRRPQTDS---SLEQFIRSKYEHKRYIAKEWIPPTPTVDV 392
GN+ +++E L + +P D+ E++IR+KYE K ++A P P+ DV
Sbjct: 699 GNALANSVWEGAL-GGYSKPGPDACREEKERWIRAKYEQKLFLA-----PLPSSDV 748
>sp|Q96P50|CENB5_HUMAN Centaurin-beta 5 (Cnt-b5)
Length = 759
Score = 104 bits (260), Expect = 3e-22
Identities = 52/111 (46%), Positives = 68/111 (61%), Gaps = 4/111 (3%)
Frame = +3
Query: 54 NKYCVDCDSKGPRWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEI 233
N C DC PRWAS LG+ LCI C+GIHR+LGVH S+V+S+ LDSW P+ + +M E+
Sbjct: 373 NSQCGDCGQPDPRWASINLGVLLCIECSGIHRSLGVHCSKVRSLTLDSWEPELLKLMCEL 432
Query: 234 GNSRGRAIYEANLEDNFRRPQTDSSLEQ----FIRSKYEHKRYIAKEWIPP 374
GNS IYEA E R T SS Q +I+ KY K+++ K + P
Sbjct: 433 GNSAVNQIYEAQCEGAGSRKPTASSSRQDKEAWIKDKYVEKKFLRKAPMAP 483
>sp|Q8BXK8|CENG2_MOUSE Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin
repeat and pleckstrin homology domains 1) (AGAP1)
Length = 857
Score = 104 bits (260), Expect = 3e-22
Identities = 47/104 (45%), Positives = 69/104 (66%), Gaps = 3/104 (2%)
Frame = +3
Query: 54 NKYCVDCDSKGPRWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEI 233
N +CVDCD++ P WAS LG +CI C+GIHRNLG HLSRV+S++LD W + + +M I
Sbjct: 621 NSHCVDCDTQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPMELIKVMSSI 680
Query: 234 GNSRGRAIYEANLEDNFRRPQTDSSLEQ---FIRSKYEHKRYIA 356
GN +++E + +P DS+ E+ +IR+KYE K ++A
Sbjct: 681 GNELANSVWEEGSQGR-TKPSLDSTREEKERWIRAKYEQKLFLA 723
>sp|Q9UPQ3|CENG2_HUMAN Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin
repeat and pleckstrin homology domains 1) (AGAP1)
Length = 857
Score = 103 bits (257), Expect = 6e-22
Identities = 46/104 (44%), Positives = 70/104 (67%), Gaps = 3/104 (2%)
Frame = +3
Query: 54 NKYCVDCDSKGPRWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEI 233
N +CVDC+++ P WAS LG +CI C+GIHRNLG HLSRV+S++LD W + + +M I
Sbjct: 621 NSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPIELIKVMSSI 680
Query: 234 GNSRGRAIYEANLEDNFRRPQTDSSLEQ---FIRSKYEHKRYIA 356
GN +++E + + +P DS+ E+ +IR+KYE K ++A
Sbjct: 681 GNELANSVWEESSQGR-TKPSVDSTREEKERWIRAKYEQKLFLA 723
>sp|Q15057|CENB2_HUMAN Centaurin-beta 2 (Cnt-b2)
Length = 778
Score = 102 bits (255), Expect = 1e-21
Identities = 50/112 (44%), Positives = 72/112 (64%), Gaps = 3/112 (2%)
Frame = +3
Query: 54 NKYCVDCDSKGPRWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEI 233
N C DC PRWAS LGI LCI C+GIHR+LGVH S+V+S+ LD+W P+ + +M E+
Sbjct: 411 NASCCDCGLADPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCEL 470
Query: 234 GNSRGRAIYEANLED-NFRRPQTDSSLEQ--FIRSKYEHKRYIAKEWIPPTP 380
GN +YEAN+E ++PQ E+ +IR+KY ++++ K I +P
Sbjct: 471 GNDVINRVYEANVEKMGIKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSP 522
>sp|Q9NGC3|CEG1A_DROME Centaurin-gamma 1A
Length = 995
Score = 102 bits (253), Expect = 2e-21
Identities = 61/174 (35%), Positives = 96/174 (55%), Gaps = 9/174 (5%)
Frame = +3
Query: 15 LQIILAELLKDDDNKYCVDCDSKGPRWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLD 194
L +LA + N +CVDC + P WAS LG+ +CI C+G+HRNLG H+S+V+S+ LD
Sbjct: 701 LAAMLAIRQRVPGNGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLGSHISKVRSLGLD 760
Query: 195 SWTPQQVAMMKEIGNSRGRAIYEANLEDNFRRPQTDSS---LEQFIRSKYEHKRYI---- 353
W +++M IGNS +++E+N +P + +S E+++RSKYE K ++
Sbjct: 761 DWPSPHLSVMLAIGNSLANSVWESNTRQRV-KPTSQASREDKERWVRSKYEAKEFLTPLG 819
Query: 354 --AKEWIPPTPTVDVIAEEIRKLEQNQNKKRVNYNNTVTNAIIPLSRRDNIETP 509
+ P+P +I IR ++ N + VTNA + S RD + TP
Sbjct: 820 NGSSAHPSPSPGQQLIEAVIRADIKSIVSILANCPSEVTNANV--SARD-VRTP 870
>sp|Q15027|CENB1_HUMAN Centaurin-beta 1 (Cnt-b1)
Length = 740
Score = 100 bits (249), Expect = 5e-21
Identities = 48/122 (39%), Positives = 75/122 (61%), Gaps = 1/122 (0%)
Frame = +3
Query: 24 ILAELLKDDDNKYCVDCDSKGPRWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWT 203
++A++ D N C DC P WAS LG+ LCI+C+GIHR+LGVH S+V+S+ LDSW
Sbjct: 407 VVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWE 466
Query: 204 PQQVAMMKEIGNSRGRAIYEANLED-NFRRPQTDSSLEQFIRSKYEHKRYIAKEWIPPTP 380
P+ V +M E+GN IYEA +E ++P S ++ + + H +Y+ K+++ P
Sbjct: 467 PELVKLMCELGNVIINQIYEARVEAMAVKKPGPSCSRQE--KEAWIHAKYVEKKFLTKLP 524
Query: 381 TV 386
+
Sbjct: 525 EI 526
>sp|O75689|CENA1_HUMAN Centaurin-alpha 1 (Putative MAPK-activating protein PM25)
Length = 374
Score = 98.6 bits (244), Expect = 2e-20
Identities = 51/113 (45%), Positives = 71/113 (62%), Gaps = 3/113 (2%)
Frame = +3
Query: 33 ELLKDDDNKYCVDCDSKGPRWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQ 212
ELL+ N C DC + P WAS+TLG+F+C+ C+GIHRN+ +S+VKSV LD+W Q
Sbjct: 11 ELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVSKVKSVRLDAWEEAQ 69
Query: 213 VAMMKEIGNSRGRAIYEANLEDNFRRP-QTDSSL--EQFIRSKYEHKRYIAKE 362
V M GN RA +E+ + + RP +D L EQ+IR+KYE + +I E
Sbjct: 70 VEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYPE 122
>sp|O74345|UCP3_SCHPO UBA-domain containing protein 3
Length = 601
Score = 98.2 bits (243), Expect = 2e-20
Identities = 44/103 (42%), Positives = 62/103 (60%), Gaps = 3/103 (2%)
Frame = +3
Query: 54 NKYCVDCDSKGPRWASWTLGIFLCIRCAGIHRNLGVHLSRVKSVNLDSWTPQQVAMMKEI 233
N C DC ++G +WASW LGIFLC+RCA IHR LG H+S+VKS++LD W+ Q+ MK
Sbjct: 20 NNLCADCSTRGVQWASWNLGIFLCLRCATIHRKLGTHVSKVKSISLDEWSNDQIEKMKHW 79
Query: 234 GNSRGRAIYEANLEDN---FRRPQTDSSLEQFIRSKYEHKRYI 353
GN + N + + +E++IR KYE K ++
Sbjct: 80 GNINANRYWNPNPLSHPLPTNALSDEHVMEKYIRDKYERKLFL 122
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,236,229
Number of Sequences: 369166
Number of extensions: 1447877
Number of successful extensions: 4307
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4147
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4279
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7763237265
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)