Planaria EST Database

DrC_00834

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00834
         (1767 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P42356|PI4KA_HUMAN  Phosphatidylinositol 4-kinase alpha (...   372   e-102
sp|P37297|STT4_YEAST  Phosphatidylinositol 4-kinase STT4 (PI...   275   2e-73
sp|Q9UBF8|PI4KB_HUMAN  Phosphatidylinositol 4-kinase beta (P...   189   3e-47
sp|O08561|PI4KB_RAT  Phosphatidylinositol 4-kinase beta (Ptd...   187   1e-46
sp|Q8BKC8|PI4KB_MOUSE  Phosphatidylinositol 4-kinase beta (P...   187   1e-46
sp|P54677|PI4K_DICDI  Phosphatidylinositol 4-kinase (PI4-kin...   186   2e-46
sp|O02810|PI4KB_BOVIN  Phosphatidylinositol 4-kinase beta (P...   186   2e-46
sp|Q9UW24|PIK1A_CANAL  Phosphatidylinositol 4-kinase PIK1a (...   158   4e-38
sp|Q9UW20|PIK1_CANAL  Phosphatidylinositol 4-kinase PIK1alph...   158   4e-38
sp|P39104|PIK1_YEAST  Phosphatidylinositol 4-kinase PIK1 (PI...   157   7e-38

>sp|P42356|PI4KA_HUMAN Phosphatidylinositol 4-kinase alpha (PI4-kinase) (PtdIns-4-kinase)
            (PI4K-alpha)
          Length = 2044

 Score =  372 bits (954), Expect = e-102
 Identities = 170/261 (65%), Positives = 221/261 (84%)
 Frame = +3

Query: 801  IYYQACIFKVGDDVRQDILALQVIRLFKNILEREGLDHYLYPYRVVATSPGCGVIECVPD 980
            I +QA IFKVGDD RQD+LALQ+I LFKNI +  GLD +++PYRVVAT+PGCGVIEC+PD
Sbjct: 1784 ISWQAAIFKVGDDCRQDMLALQIIDLFKNIFQLVGLDLFVFPYRVVATAPGCGVIECIPD 1843

Query: 981  SKSRDQIGRTTDSGMYDYFLSLFGEETTPSYQEARRNFVMSMASYSVVCYLLQIKDRHNG 1160
              SRDQ+GR TD GMYDYF   +G+E+T ++Q+AR NF+ SMA+YS++ +LLQIKDRHNG
Sbjct: 1844 CTSRDQLGRQTDFGMYDYFTRQYGDESTLAFQQARYNFIRSMAAYSLLLFLLQIKDRHNG 1903

Query: 1161 NIMIDKHGHIIHIDFGFMFESSPGNNMGFEPDIKLTKEMMMVMGGKLDSPAFQWFEQLSV 1340
            NIM+DK GHIIHIDFGFMFESSPG N+G+EPDIKLT EM+M+MGGK+++  F+WF ++ V
Sbjct: 1904 NIMLDKKGHIIHIDFGFMFESSPGGNLGWEPDIKLTDEMVMIMGGKMEATPFKWFMEMCV 1963

Query: 1341 QAYLVLRPYQEALVALVSLMLDSGLPCFRGQTIKLLRQRFTPLMSDRDAANHYLRVLRTC 1520
            + YL +RPY +A+V+LV+LMLD+GLPCFRGQTIKLL+ RF+P M++R+AAN  ++V+++C
Sbjct: 1964 RGYLAVRPYMDAVVSLVTLMLDTGLPCFRGQTIKLLKHRFSPNMTEREAANFIMKVIQSC 2023

Query: 1521 CDHWRANTYDFIQYFQNQIPY 1583
                R+ TYD IQY+QN IPY
Sbjct: 2024 FLSNRSRTYDMIQYYQNDIPY 2044


 Score =  295 bits (756), Expect = 2e-79
 Identities = 139/224 (62%), Positives = 173/224 (77%), Gaps = 3/224 (1%)
 Frame = +2

Query: 20   DIPELCYVPTWXXXXXXXXLSFFSRMYPQHPLTHQYAVKVLSLYPPDTLIFYVPQLVQGI 199
            D PEL +V  W        LS+FS MYP HPLT QY VKVL  +PPD ++FY+PQ+VQ +
Sbjct: 1544 DAPELSHVLCWAPTDPPTGLSYFSSMYPPHPLTAQYGVKVLRSFPPDAILFYIPQIVQAL 1603

Query: 200  RYDKMGYLTEFILEIVHLSPILAHQLIWNMKTNMYKDEDGQVKDPDIGLQLESVIDEINK 379
            RYDKMGY+ E+IL     S +LAHQ IWNMKTN+Y DE+G  KDPDIG  L+ +++EI  
Sbjct: 1604 RYDKMGYVREYILWAASKSQLLAHQFIWNMKTNIYLDEEGHQKDPDIGDLLDQLVEEITG 1663

Query: 380  SFSGMSLSFSEREFDFFDKITNVSGVIRPYPKGQQRQQACLEALRKIELQPGCYLPSNPD 559
            S SG +  F +REFDFF+KITNVS +I+PYPKG +R++ACL AL ++++QPGCYLPSNP+
Sbjct: 1664 SLSGPAKDFYQREFDFFNKITNVSAIIKPYPKGDERKKACLSALSEVKVQPGCYLPSNPE 1723

Query: 560  AIVLEIDYLSGIPLQSAAKAPYLAKFKVKRCGVQKLEK---KCR 682
            AIVL+IDY SG P+QSAAKAPYLAKFKVKRCGV +LEK   +CR
Sbjct: 1724 AIVLDIDYKSGTPMQSAAKAPYLAKFKVKRCGVSELEKEGLRCR 1767

>sp|P37297|STT4_YEAST Phosphatidylinositol 4-kinase STT4 (PI4-kinase) (PtdIns-4-kinase)
          Length = 1900

 Score =  275 bits (704), Expect = 2e-73
 Identities = 145/282 (51%), Positives = 191/282 (67%), Gaps = 3/282 (1%)
 Frame = +3

Query: 747  THEIKENRKNNPID--NKDDIYYQACIFKVGDDVRQDILALQVIRLFKNILEREGLDHYL 920
            T +IK++ K+ P+   NK+   +QA IFKVGDD RQD+LALQ+I LF+ I    GLD Y+
Sbjct: 1620 TFKIKKDVKD-PLTGKNKEVEKWQAAIFKVGDDCRQDVLALQLISLFRTIWSSIGLDVYV 1678

Query: 921  YPYRVVATSPGCGVIECVPDSKSRDQIGRTTDSGMYDYFLSLFGEETTPSYQEARRNFVM 1100
            +PYRV AT+PGCGVI+ +P+S SRD +GR   +G+Y+YF S FG E+T  +Q AR NFV 
Sbjct: 1679 FPYRVTATAPGCGVIDVLPNSVSRDMLGREAVNGLYEYFTSKFGNESTIEFQNARNNFVK 1738

Query: 1101 SMASYSVVCYLLQIKDRHNGNIMIDKHGHIIHIDFGFMFESSPGNNMGFEPDIKLTKEMM 1280
            S+A YSV+ YLLQ KDRHNGNIM D  GH +HIDFGF+F+  PG         KLTKEM+
Sbjct: 1739 SLAGYSVISYLLQFKDRHNGNIMYDDQGHCLHIDFGFIFDIVPGGIKFEAVPFKLTKEMV 1798

Query: 1281 MVMGGKLDSPAFQWFEQLSVQAYLVLRPYQEALVALVSLMLDSGLPCFRG-QTIKLLRQR 1457
             VMGG   +PA+  FE+L ++AYL  RP+ EA++  V+ ML SGLPCF+G +TI+ LR R
Sbjct: 1799 KVMGGSPQTPAYLDFEELCIKAYLAARPHVEAIIECVNPMLGSGLPCFKGHKTIRNLRAR 1858

Query: 1458 FTPLMSDRDAANHYLRVLRTCCDHWRANTYDFIQYFQNQIPY 1583
            F P  +D +AA +   ++R   +      YD  Q   N IPY
Sbjct: 1859 FQPQKTDHEAALYMKALIRKSYESIFTKGYDEFQRLTNGIPY 1900


 Score =  159 bits (402), Expect = 2e-38
 Identities = 82/215 (38%), Positives = 129/215 (60%), Gaps = 2/215 (0%)
 Frame = +2

Query: 50   WXXXXXXXXLSFFSRMYPQHPLTHQYAVKVLSLYPPDTLIFYVPQLVQGIRYDKMGYLTE 229
            W        ++ F   +  +    Q+++  L     +   FYVPQ+VQ +RYDK GY+  
Sbjct: 1425 WAPVSPLKSINLFLPEWQGNSFILQFSIYSLESQDVNLAFFYVPQIVQCLRYDKTGYVER 1484

Query: 230  FILEIVHLSPILAHQLIWNMKTNMYKDEDGQVKDPDIGLQLESVIDEINKSFSGMSLSFS 409
             IL+   +S + +HQ+IWNM  N YKD++G +++ +I   L+ + + +  SFS     F 
Sbjct: 1485 LILDTAKISVLFSHQIIWNMLANCYKDDEG-IQEDEIKPTLDRIRERMVSSFSQSHRDFY 1543

Query: 410  EREFDFFDKITNVSGVIRPYPKGQ--QRQQACLEALRKIELQPGCYLPSNPDAIVLEIDY 583
            EREF+FFD++T +SG ++PY K    +++    E + KIE++P  YLPSNPD +V++ID 
Sbjct: 1544 EREFEFFDEVTGISGKLKPYIKKSKAEKKHKIDEEMSKIEVKPDVYLPSNPDGVVIDIDR 1603

Query: 584  LSGIPLQSAAKAPYLAKFKVKRCGVQKLEKKCRDV 688
             SG PLQS AKAP++A FK+K+     L  K ++V
Sbjct: 1604 KSGKPLQSHAKAPFMATFKIKKDVKDPLTGKNKEV 1638

>sp|Q9UBF8|PI4KB_HUMAN Phosphatidylinositol 4-kinase beta (PtdIns 4-kinase) (PI4Kbeta)
            (PI4K-beta) (NPIK) (PI4K92)
          Length = 816

 Score =  189 bits (479), Expect = 3e-47
 Identities = 107/278 (38%), Positives = 164/278 (58%), Gaps = 3/278 (1%)
 Frame = +3

Query: 753  EIKENRKNNPIDNKDDIYYQACIFKVGDDVRQDILALQVIRLFKNILEREGLDHYLYPYR 932
            +++  R+ +P  +  +    + I K GDD+RQ++LA QV++  ++I E+E +  ++ PY+
Sbjct: 540  KVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYK 599

Query: 933  VVATSPGCGVIECVPDSKSRDQIGRTTDSGMYDYFLSLFGEETTPSYQEARRNFVMSMAS 1112
            ++  S   G+IE V ++ S  Q+ + +   + DYFL   G  TT ++  A+RNFV S A 
Sbjct: 600  ILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAG 659

Query: 1113 YSVVCYLLQIKDRHNGNIMIDKHGHIIHIDFGFMFESSPGNNMGFEPD-IKLTKEMMMVM 1289
            Y +VCYLLQ+KDRHNGNI++D  GHIIHIDFGF+  SSP  N+GFE    KLT E + VM
Sbjct: 660  YCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSP-RNLGFETSAFKLTTEFVDVM 718

Query: 1290 GGKLDSPAFQWFEQLSVQAYLVLRPYQEALVALVSLMLD-SGLPCFRG-QTIKLLRQRFT 1463
            GG LD   F +++ L +Q  +  R + + +V +V +M   S LPCF G  TI+ L++RF 
Sbjct: 719  GG-LDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFH 777

Query: 1464 PLMSDRDAANHYLRVLRTCCDHWRANTYDFIQYFQNQI 1577
              M++        +++           YD  QY  N I
Sbjct: 778  MSMTEEQLQLLVEQMVDGSMRSITTKLYDGFQYLTNGI 815

>sp|O08561|PI4KB_RAT Phosphatidylinositol 4-kinase beta (PtdIns 4-kinase) (PI4Kbeta)
            (PI4K-beta)
          Length = 816

 Score =  187 bits (474), Expect = 1e-46
 Identities = 106/278 (38%), Positives = 164/278 (58%), Gaps = 3/278 (1%)
 Frame = +3

Query: 753  EIKENRKNNPIDNKDDIYYQACIFKVGDDVRQDILALQVIRLFKNILEREGLDHYLYPYR 932
            +++  R+ +P  +  +    + I K GDD+RQ++LA QV++  ++I E+E +  ++ PY+
Sbjct: 540  KVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYK 599

Query: 933  VVATSPGCGVIECVPDSKSRDQIGRTTDSGMYDYFLSLFGEETTPSYQEARRNFVMSMAS 1112
            ++  S   G+IE V ++ S  Q+ + +   + DYFL   G  TT ++  A+RNFV S A 
Sbjct: 600  ILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAG 659

Query: 1113 YSVVCYLLQIKDRHNGNIMIDKHGHIIHIDFGFMFESSPGNNMGFEPD-IKLTKEMMMVM 1289
            Y +VCYLLQ+KDRHNGNI++D  GHIIHIDFGF+  SSP  N+GFE    KLT E + VM
Sbjct: 660  YCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSP-RNLGFETSAFKLTTEFVDVM 718

Query: 1290 GGKLDSPAFQWFEQLSVQAYLVLRPYQEALVALVSLMLD-SGLPCFRG-QTIKLLRQRFT 1463
            GG L+   F +++ L +Q  +  R + + +V +V +M   S LPCF G  TI+ L++RF 
Sbjct: 719  GG-LNGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFH 777

Query: 1464 PLMSDRDAANHYLRVLRTCCDHWRANTYDFIQYFQNQI 1577
              M++        +++           YD  QY  N I
Sbjct: 778  MSMTEEQLQLLVEQMVDGSMRSITTKLYDGFQYLTNGI 815

>sp|Q8BKC8|PI4KB_MOUSE Phosphatidylinositol 4-kinase beta (PtdIns 4-kinase) (PI4Kbeta)
            (PI4K-beta)
          Length = 801

 Score =  187 bits (474), Expect = 1e-46
 Identities = 106/278 (38%), Positives = 164/278 (58%), Gaps = 3/278 (1%)
 Frame = +3

Query: 753  EIKENRKNNPIDNKDDIYYQACIFKVGDDVRQDILALQVIRLFKNILEREGLDHYLYPYR 932
            +++  R+ +P  +  +    + I K GDD+RQ++LA QV++  ++I E+E +  ++ PY+
Sbjct: 525  KVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYK 584

Query: 933  VVATSPGCGVIECVPDSKSRDQIGRTTDSGMYDYFLSLFGEETTPSYQEARRNFVMSMAS 1112
            ++  S   G+IE V ++ S  Q+ + +   + DYFL   G  TT ++  A+RNFV S A 
Sbjct: 585  ILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAG 644

Query: 1113 YSVVCYLLQIKDRHNGNIMIDKHGHIIHIDFGFMFESSPGNNMGFEPD-IKLTKEMMMVM 1289
            Y +VCYLLQ+KDRHNGNI++D  GHIIHIDFGF+  SSP  N+GFE    KLT E + VM
Sbjct: 645  YCLVCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSP-RNLGFETSAFKLTTEFVDVM 703

Query: 1290 GGKLDSPAFQWFEQLSVQAYLVLRPYQEALVALVSLMLD-SGLPCFRG-QTIKLLRQRFT 1463
            GG L+   F +++ L +Q  +  R + + +V +V +M   S LPCF G  TI+ L++RF 
Sbjct: 704  GG-LNGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFH 762

Query: 1464 PLMSDRDAANHYLRVLRTCCDHWRANTYDFIQYFQNQI 1577
              M++        +++           YD  QY  N I
Sbjct: 763  MSMTEEQLQLLVEQMVDGSMRSITTKLYDGFQYLTNGI 800

>sp|P54677|PI4K_DICDI Phosphatidylinositol 4-kinase (PI4-kinase) (PtdIns-4-kinase)
            (PI4K-alpha)
          Length = 1093

 Score =  186 bits (472), Expect = 2e-46
 Identities = 103/280 (36%), Positives = 169/280 (60%), Gaps = 5/280 (1%)
 Frame = +3

Query: 753  EIKENRKNNPIDNKDDIYYQACIFKVGDDVRQDILALQVIRLFKNILEREGLDHYLYPYR 932
            +I+  +K +P  +  +    + I K GDD RQ+ +A+Q+I  F  I +   L  YL PY 
Sbjct: 813  KIERYKKISPFGDYPNWRLYSVIVKTGDDCRQEQMAVQLISKFDEIWKETRLPLYLRPYS 872

Query: 933  VVATSPGCGVIECVPDSKSRDQIGRTTD--SGMYDYFLSLFGEETTPSYQEARRNFVMSM 1106
            ++ TS G G+IE +PD+ S   + ++T   + + +YF S +G+ +   ++ A+ NF+ SM
Sbjct: 873  ILVTSSGGGIIETIPDTMSLHNLKKSTPGFTTLLNYFKSTYGDPSGLRFRTAQSNFIESM 932

Query: 1107 ASYSVVCYLLQIKDRHNGNIMIDKHGHIIHIDFGFMFESSPGNNMGFEPDIKLTKEMMMV 1286
            A+YS+V Y+LQIKDRHNGNI+IDK GHI+HIDFGF+  +SPGN        KLT+E++ V
Sbjct: 933  AAYSIVTYILQIKDRHNGNILIDKEGHIVHIDFGFILSNSPGNISFESAPFKLTQELVDV 992

Query: 1287 MGGKLDSPAFQWFEQLSVQAYLVLRPYQEALVALVSLMLDS-GLPCFRG--QTIKLLRQR 1457
            MGG + S  FQ+F+ L V+  +  R   + +++L+ +M+    + CF G  + I+ L+ R
Sbjct: 993  MGG-IQSGQFQYFKVLCVRGLIEARKQVDKIISLIEIMMSGPKMSCFVGGKEVIEQLKAR 1051

Query: 1458 FTPLMSDRDAANHYLRVLRTCCDHWRANTYDFIQYFQNQI 1577
            F   +++R+ +     ++    DH++   YD  Q + N I
Sbjct: 1052 FFLDVNERECSTLVENLISYSIDHFKTRYYDKYQSWLNGI 1091

>sp|O02810|PI4KB_BOVIN Phosphatidylinositol 4-kinase beta (PtdIns 4-kinase) (PI4Kbeta)
            (PI4K-beta)
          Length = 816

 Score =  186 bits (472), Expect = 2e-46
 Identities = 106/278 (38%), Positives = 163/278 (58%), Gaps = 3/278 (1%)
 Frame = +3

Query: 753  EIKENRKNNPIDNKDDIYYQACIFKVGDDVRQDILALQVIRLFKNILEREGLDHYLYPYR 932
            +++  R+ +P  +  +    + I K GDD+RQ++LA QV++  ++I E+E +  ++ PY+
Sbjct: 540  KVRRIREGSPYGHLPNWRLLSVIVKCGDDLRQELLAFQVLKQLQSIWEQERVPLWIKPYK 599

Query: 933  VVATSPGCGVIECVPDSKSRDQIGRTTDSGMYDYFLSLFGEETTPSYQEARRNFVMSMAS 1112
            ++  S   G+IE V ++ S  Q+ + +   + DYFL   G  TT ++  A+RNFV S A 
Sbjct: 600  ILVISADSGMIEPVVNAVSIHQVKKQSQLSLLDYFLQEHGSYTTEAFLSAQRNFVQSCAG 659

Query: 1113 YSVVCYLLQIKDRHNGNIMIDKHGHIIHIDFGFMFESSPGNNMGFEPD-IKLTKEMMMVM 1289
            Y + CYLLQ+KDRHNGNI++D  GHIIHIDFGF+  SSP  N+GFE    KLT E + VM
Sbjct: 660  YCLGCYLLQVKDRHNGNILLDAEGHIIHIDFGFILSSSP-RNLGFETSAFKLTTEFVDVM 718

Query: 1290 GGKLDSPAFQWFEQLSVQAYLVLRPYQEALVALVSLMLD-SGLPCFRG-QTIKLLRQRFT 1463
            GG LD   F +++ L +Q  +  R + + +V +V +M   S LPCF G  TI+ L++RF 
Sbjct: 719  GG-LDGDMFNYYKMLMLQGLIAARKHMDKVVQIVEIMQQGSQLPCFHGSSTIRNLKERFH 777

Query: 1464 PLMSDRDAANHYLRVLRTCCDHWRANTYDFIQYFQNQI 1577
              M++        +++           YD  QY  N I
Sbjct: 778  MSMTEEQLQLLVEQMVDGSMRSITTKLYDGFQYLTNGI 815

>sp|Q9UW24|PIK1A_CANAL Phosphatidylinositol 4-kinase PIK1a (PI4-kinase) (PtdIns-4-kinase)
          Length = 956

 Score =  158 bits (400), Expect = 4e-38
 Identities = 99/271 (36%), Positives = 154/271 (56%), Gaps = 18/271 (6%)
 Frame = +3

Query: 726  ANNFKKQTHEIKENRKNNPIDNKDDIYYQACIFKVGDDVRQDILALQVIRLFKNILEREG 905
            A ++ ++ H I+++     ++N D     + I K GDD+ Q+  A Q+I L  NI ++  
Sbjct: 657  AEDWNEKKHRIRKSSIYGHLENWD---LCSVIVKNGDDLPQEAFACQLISLISNIWKKHK 713

Query: 906  LDHYLYPYRVVATSPGCGVIECVPDSKSRDQIGRTT-----DSG---------MYDYFLS 1043
            +D +    +++ TS   G++E + ++ S   I ++      ++G         + DYF  
Sbjct: 714  VDFWTKRMKILITSANAGLVETITNAMSIHSIKKSLTELSIENGENAKGRIFTLKDYFQK 773

Query: 1044 LFGEETTPSYQEARRNFVMSMASYSVVCYLLQIKDRHNGNIMIDKHGHIIHIDFGFMFES 1223
            L+G   +  Y +A+ NF +S+ASYS++CY+LQIKDRHNGNIM+D  GHIIHIDFGF+  +
Sbjct: 774  LYGSVDSSKYVKAQENFAISLASYSIICYVLQIKDRHNGNIMLDHEGHIIHIDFGFLLSN 833

Query: 1224 SPGNNMGFE-PDIKLTKEMMMVMGGKLDSPAFQWFEQLSVQAYLVLRPYQEALVALVSLM 1400
            SPG ++GFE    KLT E + V+GG L+S A+  F       +  LR     +V++V LM
Sbjct: 834  SPG-SVGFEAAPFKLTSEYVEVLGG-LESKAYLKFVDTCKNCFKALRKEWGQIVSIVELM 891

Query: 1401 -LDSGLPCFRG--QTIKLLRQRFTPLMSDRD 1484
               S LPCF     T  LL+QR    +SD +
Sbjct: 892  QKGSSLPCFNNGDNTSVLLQQRLQLHLSDEE 922

>sp|Q9UW20|PIK1_CANAL Phosphatidylinositol 4-kinase PIK1alpha (PI4-kinase)
            (PtdIns-4-kinase)
          Length = 977

 Score =  158 bits (400), Expect = 4e-38
 Identities = 102/269 (37%), Positives = 153/269 (56%), Gaps = 18/269 (6%)
 Frame = +3

Query: 732  NFKKQTHEIKENRKNNPIDNKDDIYYQACIFKVGDDVRQDILALQVIRLFKNILEREGLD 911
            N KKQ   IK++     + N D     + I K GDD+ Q+  A Q+I +  NI ++  + 
Sbjct: 682  NTKKQ--RIKKSSAYGHLKNWD---LCSVIAKNGDDLPQEAFACQLISMISNIWKKNNIP 736

Query: 912  HYLYPYRVVATSPGCGVIECVPDSKSRDQIGRT-----TDSG---------MYDYFLSLF 1049
             +    +++ TS   G++E + ++ S   I ++       SG         + DYF S+F
Sbjct: 737  VWTKRMKILITSANTGLVETITNAMSIHSIKKSFTEHSIKSGENSKGKIFTLLDYFHSVF 796

Query: 1050 GEETTPSYQEARRNFVMSMASYSVVCYLLQIKDRHNGNIMIDKHGHIIHIDFGFMFESSP 1229
            G   + S++ A++NF  S+A+YS++CY+LQIKDRHNGNIM+D  GHIIHIDFGF+  +SP
Sbjct: 797  GSPNSTSFRTAQQNFAKSLAAYSIICYVLQIKDRHNGNIMVDGDGHIIHIDFGFLLSNSP 856

Query: 1230 GNNMGFE-PDIKLTKEMMMVMGGKLDSPAFQWFEQLSVQAYLVLRPYQEALVALVSLM-L 1403
            G ++GFE    KLT E + ++GG +DS  +  F  L  Q +  LR   E ++ +V LM  
Sbjct: 857  G-SVGFEAAPFKLTVEYVELLGG-VDSEIYSQFVYLCKQCFKSLRDNSEEIIEIVELMQK 914

Query: 1404 DSGLPCFRG--QTIKLLRQRFTPLMSDRD 1484
            DS LPCF     T  LL+QR    ++D D
Sbjct: 915  DSTLPCFNNGENTSVLLKQRLQLQLNDED 943

>sp|P39104|PIK1_YEAST Phosphatidylinositol 4-kinase PIK1 (PI4-kinase) (PtdIns-4-kinase)
          Length = 1066

 Score =  157 bits (398), Expect = 7e-38
 Identities = 93/241 (38%), Positives = 141/241 (58%), Gaps = 19/241 (7%)
 Frame = +3

Query: 819  IFKVGDDVRQDILALQVIRLFKNILEREGLDHYLYPYRVVATSPGCGVIECVPDSKSRDQ 998
            I K GDD+RQ+  A Q+I+   NI  +E +D ++   +++ TS   G++E + ++ S   
Sbjct: 794  IAKTGDDLRQEAFAYQMIQAMANIWVKEKVDVWVKRMKILITSANTGLVETITNAMSVHS 853

Query: 999  IGRTTDSGMY---------------DYFLSLFGEETTPSYQEARRNFVMSMASYSVVCYL 1133
            I +     M                D+FL  FG      Y+ A+ NF  S+A+YSV+CYL
Sbjct: 854  IKKALTKKMIEDAELDDKGGIASLNDHFLRAFGNPNGFKYRRAQDNFASSLAAYSVICYL 913

Query: 1134 LQIKDRHNGNIMIDKHGHIIHIDFGFMFESSPGNNMGFE-PDIKLTKEMMMVMGGKLDSP 1310
            LQ+KDRHNGNIMID  GH+ HIDFGFM  +SPG ++GFE    KLT E + ++GG ++  
Sbjct: 914  LQVKDRHNGNIMIDNEGHVSHIDFGFMLSNSPG-SVGFEAAPFKLTYEYIELLGG-VEGE 971

Query: 1311 AFQWFEQLSVQAYLVLRPYQEALVALVSLM-LDSGLPCFRG--QTIKLLRQRFTPLMSDR 1481
            AF+ F +L+  ++  LR Y + +V++  +M  D+  PCF    QT   LRQRF   +S++
Sbjct: 972  AFKKFVELTKSSFKALRKYADQIVSMCEIMQKDNMQPCFDAGEQTSVQLRQRFQLDLSEK 1031

Query: 1482 D 1484
            +
Sbjct: 1032 E 1032

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 191,546,594
Number of Sequences: 369166
Number of extensions: 3825499
Number of successful extensions: 9595
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 8940
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9517
length of database: 68,354,980
effective HSP length: 116
effective length of database: 46,925,720
effective search space used: 22148939840
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00834

  1. Dr_sW_021_D14
  2. Dr_sW_019_G11
  3. Dr_sW_009_N23
  4. Dr_sW_027_D22