Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00772 (1026 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q8LAX0|HMT3_ARATH Homocysteine S-methyltransferase 3 (S-... 153 7e-37 sp|Q9FUN0|HMT1_MAIZE Homocysteine S-methyltransferase 1 (S-... 149 2e-35 sp|Q9SDL7|HMT1_ARATH Homocysteine S-methyltransferase 1 (S-... 144 5e-34 sp|Q9FUM9|HMT2_MAIZE Homocysteine S-methyltransferase 2 (S-... 140 8e-33 sp|Q9FUM8|HMT3_MAIZE Homocysteine S-methyltransferase 3 (S-... 139 2e-32 sp|P56707|SMTA_ASTBI Selenocysteine methyltransferase (SECY... 135 2e-31 sp|Q9FUM7|HMT4_MAIZE Homocysteine S-methyltransferase 4 (S-... 134 3e-31 sp|Q9M1W4|HMT2_ARATH Homocysteine S-methyltransferase 2 (S-... 134 4e-31 sp|Q47690|MMUM_ECOLI Homocysteine S-methyltransferase (S-me... 127 7e-29 sp|Q12525|MHT1_YEAST Homocysteine S-methyltransferase 1 (S-... 87 8e-17
>sp|Q8LAX0|HMT3_ARATH Homocysteine S-methyltransferase 3 (S-methylmethionine:homocysteine methyltransferase 3) (SMM:Hcy S-methyltransferase 3) (AtHMT-3) Length = 347 Score = 153 bits (387), Expect = 7e-37 Identities = 99/276 (35%), Positives = 147/276 (53%), Gaps = 14/276 (5%) Frame = +3 Query: 192 FLCAGAEVITSLSYQACPITLSSSFNMSIEDAKQLMVDSVLLAND--EILKYQ------- 344 +L +GA +I + SYQA I + +S+ +A+ L+ SV + + EI + Sbjct: 65 YLESGANIIITASYQAT-IQGFVAKGLSVGEAENLLRRSVEITYEAREIFYNRCTKGSWD 123 Query: 345 ---SSKVERTSIMSAASIGSYGAHLSDLSEYTGSYVDKVSKFDLKTYYEEQISTLLIGKP 515 + K R I+ AAS+GSYGA+L+D SEY+G Y D VSK LK ++ ++ L Sbjct: 124 FAYAGKASRRPILVAASVGSYGAYLADGSEYSGIYGDSVSKETLKDFHRRRVQILAKSGA 183 Query: 516 DILAFETMPAMLDVELIIDLMREYP-NTSAWISMTSLDGIHTAHGELLDDVIEYIN-QYS 689 D++AFET+P L+ E DL+ E + AW S TS DG+ G D V+E S Sbjct: 184 DLIAFETIPNKLEAEAYADLLEEEDIDIPAWFSFTSKDGVSVPRG---DSVVECAKVADS 240 Query: 690 TKNVIGFGLNCVIPLMVVKDTVCKIRSRLNPDKIIVLYPNTGEVLNSLNRHWYFPEGVTE 869 KNV+ G+NC P + I R K IV+YPN+GEV + LN+ W EG +E Sbjct: 241 CKNVVAIGINCTAPRYI---HALIISLRQMTRKPIVVYPNSGEVYDGLNKKWIKSEGESE 297 Query: 870 NTFYEYIPSWIEAGAEWIGGCCRMSADRMIRVSDII 977 F Y+ W +AGA GGCCR + + + ++ ++ Sbjct: 298 EDFVSYVSKWRDAGASLFGGCCRTTPNTIRAIAKVL 333
>sp|Q9FUN0|HMT1_MAIZE Homocysteine S-methyltransferase 1 (S-methylmethionine:homocysteine methyltransferase 1) (SMM:Hcy S-methyltransferase 1) (ZmHMT-1) Length = 323 Score = 149 bits (375), Expect = 2e-35 Identities = 95/271 (35%), Positives = 151/271 (55%), Gaps = 6/271 (2%) Frame = +3 Query: 186 VRFLCAGAEVITSLSYQACPITLSSSFNMSIEDAKQLMVDSVLLAN---DEILK--YQSS 350 +++L AGA+VI S SYQA I + MS+ +A+ L+ SV LAN DE K + S Sbjct: 54 MQYLEAGADVIISSSYQAT-IPGFIARGMSVAEAEDLLRTSVKLANEARDEFWKSTLRKS 112 Query: 351 KVERTSIMSAASIGSYGAHLSDLSEYTGSYVDKVSKFDLKTYYEEQISTLLIGKPDILAF 530 K + AASIGSYGA+L+D SEY+GSY ++ LK ++ ++ L PD++AF Sbjct: 113 KPIYNRALVAASIGSYGAYLADGSEYSGSYGADITAEKLKDFHRRRLQVLASAGPDLIAF 172 Query: 531 ETMPAMLDVELIIDLMREYP-NTSAWISMTSLDGIHTAHGELLDDVIEYINQYSTKNVIG 707 E +P ++ + +++L+ E +WI +S+DG + GE D ++ +N +++ V Sbjct: 173 EAIPNQMEAQALVELLEEEKVQIPSWICFSSVDGKNLCSGESFADCLKILN--ASEKVAV 230 Query: 708 FGLNCVIPLMVVKDTVCKIRSRLNPDKIIVLYPNTGEVLNSLNRHWYFPEGVTENTFYEY 887 G+NC P ++ +C+ R + K I +YPN+GEV + + W E + +F Sbjct: 231 VGVNCT-PPQFIEGIICEFRKQTK--KAIAVYPNSGEVWDGRAKRWLPVECLGHKSFDAL 287 Query: 888 IPSWIEAGAEWIGGCCRMSADRMIRVSDIIR 980 W EAGA IGGCCR + + VS I++ Sbjct: 288 AKRWQEAGASLIGGCCRTTPSTIRAVSKILK 318
>sp|Q9SDL7|HMT1_ARATH Homocysteine S-methyltransferase 1 (S-methylmethionine:homocysteine methyltransferase 1) (SMM:Hcy S-methyltransferase 1) (AtHMT-1) Length = 326 Score = 144 bits (362), Expect = 5e-34 Identities = 92/267 (34%), Positives = 152/267 (56%), Gaps = 6/267 (2%) Frame = +3 Query: 186 VRFLCAGAEVITSLSYQACPITLSSSFNMSIEDAKQLMVDSVLLANDEILKY--QSSKVE 359 + +L AGA+++ + SYQA I S +SIE+++ L+ SV LA + ++ + SKV Sbjct: 60 MEYLEAGADIVVTSSYQAT-IPGFLSRGLSIEESESLLQKSVELAVEARDRFWEKVSKVS 118 Query: 360 RTSI---MSAASIGSYGAHLSDLSEYTGSYVDKVSKFDLKTYYEEQISTLLIGKPDILAF 530 S + AASIGSYGA+L+D SEY+G Y + VS LK ++ ++ L+ PD+LAF Sbjct: 119 GHSYNRALVAASIGSYGAYLADGSEYSGHYGENVSLDKLKDFHRRRLQVLVEAGPDLLAF 178 Query: 531 ETMPAMLDVELIIDLMREYP-NTSAWISMTSLDGIHTAHGELLDDVIEYINQYSTKNVIG 707 ET+P L+ + ++L+ E AWI TS+DG GE ++ +E +N+ + N+ Sbjct: 179 ETIPNKLEAQACVELLEEEKVQIPAWICFTSVDGEKAPSGESFEECLEPLNK--SNNIYA 236 Query: 708 FGLNCVIPLMVVKDTVCKIRSRLNPDKIIVLYPNTGEVLNSLNRHWYFPEGVTENTFYEY 887 G+NC P + + + + ++L K IV+YPN+GEV + + W + ++ F + Sbjct: 237 VGINCAPPQFI--ENLIRKFAKLT-KKAIVVYPNSGEVWDGKAKQWLPSQCFGDDEFEMF 293 Query: 888 IPSWIEAGAEWIGGCCRMSADRMIRVS 968 W + GA+ IGGCCR + + +S Sbjct: 294 ATKWRDLGAKLIGGCCRTTPSTINAIS 320
>sp|Q9FUM9|HMT2_MAIZE Homocysteine S-methyltransferase 2 (S-methylmethionine:homocysteine methyltransferase 2) (SMM:Hcy S-methyltransferase 2) (ZmHMT-2) Length = 339 Score = 140 bits (352), Expect = 8e-33 Identities = 86/255 (33%), Positives = 137/255 (53%), Gaps = 6/255 (2%) Frame = +3 Query: 192 FLCAGAEVITSLSYQACPITLSSSFNMSIEDAKQLMVDSVLLANDEILKYQSSKVERTS- 368 +L AGA +I + SYQA I S S E ++ L+ SV +A + + +E+++ Sbjct: 65 YLEAGANIIITASYQAT-IQGFESKGFSKEQSENLLTKSVEIALEAREMFLKEHLEKSTP 123 Query: 369 ----IMSAASIGSYGAHLSDLSEYTGSYVDKVSKFDLKTYYEEQISTLLIGKPDILAFET 536 ++ AAS+GSYGA+L+D SEY+G Y + +K LK ++ ++ L PD++AFET Sbjct: 124 IQHPVLVAASLGSYGAYLADGSEYSGDYGEAGTKEFLKDFHRRRLQVLAEAGPDLIAFET 183 Query: 537 MPAMLDVELIIDLMREYP-NTSAWISMTSLDGIHTAHGELLDDVIEYINQYSTKNVIGFG 713 +P L+ E ++L+ E N AW S S DG+H G+ L + ++ + + G Sbjct: 184 IPNKLEAEAYVELLEECNINIPAWFSFNSKDGVHIVSGDSLIECTTIADKCAKVGAV--G 241 Query: 714 LNCVIPLMVVKDTVCKIRSRLNPDKIIVLYPNTGEVLNSLNRHWYFPEGVTENTFYEYIP 893 +NC P + + IR DK I++YPN+GE + + W GV++ F Y+ Sbjct: 242 INCT-PPRFIHGLILSIRK--VTDKPILIYPNSGERYDGEKKEWVESTGVSDGDFVSYVN 298 Query: 894 SWIEAGAEWIGGCCR 938 W + GA IGGCCR Sbjct: 299 EWCKDGAVLIGGCCR 313
>sp|Q9FUM8|HMT3_MAIZE Homocysteine S-methyltransferase 3 (S-methylmethionine:homocysteine methyltransferase 3) (SMM:Hcy S-methyltransferase 3) (ZmHMT-3) Length = 338 Score = 139 bits (349), Expect = 2e-32 Identities = 84/255 (32%), Positives = 138/255 (54%), Gaps = 6/255 (2%) Frame = +3 Query: 192 FLCAGAEVITSLSYQACPITLSSSFNMSIEDAKQLMVDSVLLANDEILKYQSSKVERTS- 368 +L AGA +I + SYQA I S S E ++ L+ SV +A + + +E+++ Sbjct: 65 YLEAGANIIITASYQAT-IQGFESKGFSKEQSENLLTKSVQIALEAREMFLKEHLEKSTP 123 Query: 369 ----IMSAASIGSYGAHLSDLSEYTGSYVDKVSKFDLKTYYEEQISTLLIGKPDILAFET 536 I+ AA++GSYGA+L+D SEY+G Y + +K LK ++ ++ L PD++AFET Sbjct: 124 IQHPILVAAALGSYGAYLADGSEYSGDYGEAGTKEFLKDFHRRRLQVLAEAGPDLIAFET 183 Query: 537 MPAMLDVELIIDLMREYP-NTSAWISMTSLDGIHTAHGELLDDVIEYINQYSTKNVIGFG 713 +P L+ + ++L+ E N +W+S S DG+H G+ L + ++ + + G Sbjct: 184 IPNKLEAQAYVELLEECNINIPSWLSFNSKDGVHVVSGDSLIECATIADKCAKVGAV--G 241 Query: 714 LNCVIPLMVVKDTVCKIRSRLNPDKIIVLYPNTGEVLNSLNRHWYFPEGVTENTFYEYIP 893 +NC P + + IR DK I++YPN+GE + + W GV++ F Y+ Sbjct: 242 INCT-PPRFIHGLILSIRK--VTDKPILIYPNSGERYDGEKKEWVESTGVSDGDFVSYVN 298 Query: 894 SWIEAGAEWIGGCCR 938 W + GA IGGCCR Sbjct: 299 EWCKDGAALIGGCCR 313
>sp|P56707|SMTA_ASTBI Selenocysteine methyltransferase (SECYS-methyltransferase) (SECYS-MT) Length = 338 Score = 135 bits (340), Expect = 2e-31 Identities = 87/278 (31%), Positives = 141/278 (50%), Gaps = 14/278 (5%) Frame = +3 Query: 192 FLCAGAEVITSLSYQACPITLSSSFNMSIEDAKQLMVDSVLLANDEILKYQSSKVERTS- 368 +L GA++I + SYQA I + S E+ + L+ SV +A + Y E +S Sbjct: 58 YLENGADIIITASYQAT-IQGFKAKGFSDEEGEALLRRSVEIAREARDLYYQRCAESSSD 116 Query: 369 ------------IMSAASIGSYGAHLSDLSEYTGSYVDKVSKFDLKTYYEEQISTLLIGK 512 I+ A S+GSYGA+L+D SE++G+Y D + LK ++ ++ L Sbjct: 117 NGDDSRILKQRPILIAGSVGSYGAYLADGSEFSGNYGDAIKSETLKDFHRRKVQILADSG 176 Query: 513 PDILAFETMPAMLDVELIIDLMREYPN-TSAWISMTSLDGIHTAHGELLDDVIEYINQYS 689 D+LAFE +P L+ + DL+ E T AW + TS DG + G+ +++ S Sbjct: 177 VDLLAFEAVPNKLEAQAYADLLEEENIITPAWFAFTSKDGNNVVSGDSIEECGSIAE--S 234 Query: 690 TKNVIGFGLNCVIPLMVVKDTVCKIRSRLNPDKIIVLYPNTGEVLNSLNRHWYFPEGVTE 869 V+ G+NC P + D + ++ K IV+YPN+GE +++ + W GVT+ Sbjct: 235 CDKVVAVGINCTPPRFI-HDLILLLKKVTA--KPIVIYPNSGETYDAIRKEWGQNSGVTD 291 Query: 870 NTFYEYIPSWIEAGAEWIGGCCRMSADRMIRVSDIIRS 983 F Y+ W E+GA +GGCCR + D + + I+ S Sbjct: 292 EDFVSYVDKWCESGASLVGGCCRTTPDTIRGIYKILSS 329
>sp|Q9FUM7|HMT4_MAIZE Homocysteine S-methyltransferase 4 (S-methylmethionine:homocysteine methyltransferase 4) (SMM:Hcy S-methyltransferase 4) (ZmHMT-4) Length = 342 Score = 134 bits (338), Expect = 3e-31 Identities = 91/272 (33%), Positives = 146/272 (53%), Gaps = 9/272 (3%) Frame = +3 Query: 192 FLCAGAEVITSLSYQACPITLSSSFNMSIEDAKQLMVDSVLLANDEILKY-----QSSKV 356 +L AGA+VI S SYQA I S S +++++L+ SV +A + + +SS+ Sbjct: 66 YLEAGADVIISASYQAT-IEGFQSRGFSRDESEELLRRSVHVAQEARRVFAAEGDRSSRR 124 Query: 357 ERTSIMSAASIGSYGAHLSDLSEYTGSYVDKVSKFDLKTYYEEQISTLLIGKPDILAFET 536 R + AAS+GSYGA+ +D SEY+G Y ++K DLK ++ ++ L PD++AFET Sbjct: 125 GRPPALVAASVGSYGAYRADGSEYSGDYGKSMTKEDLKNFHRRRLQVLAGAGPDLIAFET 184 Query: 537 MPAMLDVELIIDLMREYP-NTSAWISMTSLDGIHTAHGELLDDVIEYINQYSTKNVIGFG 713 +P L+ ++ +L+ E AW S TS DG++ A G+ +++ + S V G Sbjct: 185 IPNKLEAQVYAELLEENGIRIPAWFSFTSKDGVNAASGDPINECAAVAD--SCPRVDAVG 242 Query: 714 LNCVIPLMV--VKDTVCKIRSRLNPDKIIVLYPNTGEVLNSLNRHWYFPEGVT-ENTFYE 884 +NC P + + ++ K+ S K IV+YPN+GE + W +G T + F Sbjct: 243 VNCTAPRFIHGLILSIKKVTS-----KPIVVYPNSGETYVAETNEWVDSDGATGTDDFVS 297 Query: 885 YIPSWIEAGAEWIGGCCRMSADRMIRVSDIIR 980 + W AGA IGGCCR S + ++ +R Sbjct: 298 RVGEWRRAGAALIGGCCRTSPATVRAIARAVR 329
>sp|Q9M1W4|HMT2_ARATH Homocysteine S-methyltransferase 2 (S-methylmethionine:homocysteine methyltransferase 2) (SMM:Hcy S-methyltransferase 2) (AtHMT-2) Length = 333 Score = 134 bits (337), Expect = 4e-31 Identities = 83/260 (31%), Positives = 139/260 (53%), Gaps = 11/260 (4%) Frame = +3 Query: 192 FLCAGAEVITSLSYQACPITLSSSFNMSIEDAKQLMVDSVLLANDEILKYQ-----SSKV 356 +L AGA++I+S SYQA I + S E+++ L+ SV +A + Y SS + Sbjct: 61 YLEAGADIISSASYQAT-IQGFEAKGFSREESESLLKKSVEIATEARNSYYDKCGTSSSM 119 Query: 357 E-----RTSIMSAASIGSYGAHLSDLSEYTGSYVDKVSKFDLKTYYEEQISTLLIGKPDI 521 + + I+ AAS+GSYGA+L+D SEY+G Y D ++ LK ++ ++ L D+ Sbjct: 120 DDKILKKRPILVAASVGSYGAYLADGSEYSGIYGDSITLEKLKDFHRRRLQVLAESGADL 179 Query: 522 LAFETMPAMLDVELIIDLMREYP-NTSAWISMTSLDGIHTAHGELLDDVIEYINQYSTKN 698 +AFET+P ++ + DL+ E W S S DG++ G+ + + I + + Sbjct: 180 IAFETIPNKIEAQAFADLLEEGDVKIPGWFSFNSKDGVNVVSGDSIKECISIAE--NCEK 237 Query: 699 VIGFGLNCVIPLMVVKDTVCKIRSRLNPDKIIVLYPNTGEVLNSLNRHWYFPEGVTENTF 878 V+ G+NC P ++ V +I + K I++YPN+GE ++ + W GV + F Sbjct: 238 VVAVGINCT-PPRFIEGLVLEIEKVTS--KPILVYPNSGESYDADRKEWVENTGVGDEDF 294 Query: 879 YEYIPSWIEAGAEWIGGCCR 938 Y+ W++AG +GGCCR Sbjct: 295 VSYVEKWMDAGVSLLGGCCR 314
>sp|Q47690|MMUM_ECOLI Homocysteine S-methyltransferase (S-methylmethionine:homocysteine methyltransferase) Length = 310 Score = 127 bits (318), Expect = 7e-29 Identities = 78/247 (31%), Positives = 128/247 (51%), Gaps = 1/247 (0%) Frame = +3 Query: 201 AGAEVITSLSYQACPITLSSSFNMSIEDAKQLMVDSVLLANDEILKYQSSKVERTSIMSA 380 AGA+ + SYQA P ++ + +K L+ SV LA Y + + +++ A Sbjct: 61 AGAQCAITASYQATPAGFAAR-GLDEAQSKALIGKSVELARKAREAYLAENPQAGTLLVA 119 Query: 381 ASIGSYGAHLSDLSEYTGSYVDKVSKFDLKTYYEEQISTLLIGKPDILAFETMPAMLDVE 560 S+G YGA+L+D SEY G Y V F + ++ ++ LL D+LA ET+P ++E Sbjct: 120 GSVGPYGAYLADGSEYRGDYHCSVEAF--QAFHRPRVEALLDAGADLLACETLPNFSEIE 177 Query: 561 LIIDLMREYPNTSAWISMTSLDGIHTAHGELLDDVIEYINQYSTKNVIGFGLNCVIPLMV 740 + +L+ YP AW S T D H + G L DV+ + Y V+ G+NC+ Sbjct: 178 ALAELLTAYPRARAWFSFTLRDSEHLSDGTPLRDVVALLAGY--PQVVALGINCI----A 231 Query: 741 VKDTVCKIRSRLNPDKI-IVLYPNTGEVLNSLNRHWYFPEGVTENTFYEYIPSWIEAGAE 917 +++T ++ + +V+YPN+GE +++++ W+ G +Y+P W AGA Sbjct: 232 LENTTAALQHLHGLTVLPLVVYPNSGEHYDAVSKTWHH-HGEHCAQLADYLPQWQAAGAR 290 Query: 918 WIGGCCR 938 IGGCCR Sbjct: 291 LIGGCCR 297
>sp|Q12525|MHT1_YEAST Homocysteine S-methyltransferase 1 (S-methylmethionine:homocysteine methyltransferase 1) (SMM:Hcy S-methyltransferase 1) Length = 324 Score = 87.0 bits (214), Expect = 8e-17 Identities = 64/286 (22%), Positives = 133/286 (46%), Gaps = 4/286 (1%) Frame = +3 Query: 141 QKVIEKLLNSTSKGIVRFLCAGAEVITSLSYQACPITLSSSFNMSIEDAKQLMVDSVLLA 320 +KV+E++ F+ AGA ++ +++YQA ++S + ++ A + +D ++ Sbjct: 58 RKVVEEMYRD-------FMIAGANILMTITYQANFQSISENTSIKTLAAYKRFLDKIVSF 110 Query: 321 NDEILKYQSSKVERTSIMSAASIGSYGAHLSDLSEYTGSYVDKVSKFDLKTYYEEQISTL 500 E + + + SIG + AH+S EYTG Y D +++ Q+ Sbjct: 111 TREFIGEERYLI--------GSIGPWAAHVS--CEYTGDYGPHPENIDYYGFFKPQLENF 160 Query: 501 LIGKP-DILAFETMPAMLDVELIIDLMREYPNTSAWISMTSLDGIHTAHGELLDDV---I 668 + D++ FET+P +++ I+ + + +I ++ D G L+++ I Sbjct: 161 NQNRDIDLIGFETIPNFHELKAILSWDEDIISKPFYIGLSVDDNSLLRDGTTLEEISVHI 220 Query: 669 EYINQYSTKNVIGFGLNCVIPLMVVKDTVCKIRSRLNPDKIIVLYPNTGEVLNSLNRHWY 848 + + KN++ G+NCV + K+ P +++YPN+GE+ N + W+ Sbjct: 221 KGLGNKINKNLLLMGVNCVS--FNQSALILKMLHEHLPGMPLLVYPNSGEIYNPKEKTWH 278 Query: 849 FPEGVTENTFYEYIPSWIEAGAEWIGGCCRMSADRMIRVSDIIRSY 986 P ++ + + +++ GA IGGCCR S + ++ + Y Sbjct: 279 RPTNKLDD-WETTVKKFVDNGARIIGGCCRTSPKDIAEIASAVDKY 323
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 117,782,802 Number of Sequences: 369166 Number of extensions: 2394143 Number of successful extensions: 6969 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 6706 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6934 length of database: 68,354,980 effective HSP length: 111 effective length of database: 47,849,395 effective search space used: 11005360850 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)