DrC_00745
- Cluster detail
- GO Category : Not Available
- Consensus Sequence :
BLASTX 2.2.13 [Nov-27-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00745 (1037 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9UI08|EVL_HUMAN Ena/vasodilator-stimulated phosphoprote... 52 2e-06 sp|O08719|EVL_RAT Ena/vasodilator-stimulated phosphoprotein... 50 1e-05 sp|P70429|EVL_MOUSE Ena/vasodilator-stimulated phosphoprote... 50 1e-05 sp|P50551|VASP_CANFA Vasodilator-stimulated phosphoprotein ... 49 2e-05 sp|P50552|VASP_HUMAN Vasodilator-stimulated phosphoprotein ... 47 1e-04 sp|Q8N8S7|ENAH_HUMAN Enabled protein homolog 46 2e-04 sp|Q03173|ENAH_MOUSE Enabled protein homolog (NPC derived p... 46 2e-04 sp|P70460|VASP_MOUSE Vasodilator-stimulated phosphoprotein ... 44 8e-04 sp|Q924S8|Spre1_MOUSE Sprouty-related, EVH1 domain containi... 39 0.032 sp|Q6NYK3|Spre2_BRARE Sprouty-related, EVH1 domain containi... 39 0.032
>sp|Q9UI08|EVL_HUMAN Ena/vasodilator-stimulated phosphoprotein-like protein (Ena/VASP-like protein) Length = 416 Score = 52.4 bits (124), Expect = 2e-06 Identities = 33/111 (29%), Positives = 49/111 (44%) Frame = +1 Query: 1 LNSFLFASMNYTESTPTFHQWYDEGKNAYGLNFPDANEAKKFGIAVNSAIEILNGSKINK 180 +N + + Y ++TPTFHQW D + YGLNF EA F A+ A+ I+N S+ Sbjct: 61 INYSIVKGLKYNQATPTFHQWRD-ARQVYGLNFASKEEATTFSNAMLFALNIMN-SQEGG 118 Query: 181 PGGDNFVVPKKSVEKQPSNNPTVVSPYATAGIHQTNDSSTAKVPTLPTGKP 333 P V S ++ V+ + ++A P LP G P Sbjct: 119 PSSQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATGPILPPGHP 169
Score = 48.1 bits (113), Expect = 4e-05
Identities = 36/141 (25%), Positives = 60/141 (42%), Gaps = 4/141 (2%)
Frame = +1
Query: 499 RAKQETMKHTSTNSNADNISRESPTPPVQSTQSISSKPPKMDFLSEIKLKTQNRQDGINP 678
R K + D E P+ +S+PP SE K R + +
Sbjct: 278 RRKAASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNS---SEAGRKPWERSNSVEK 334
Query: 679 PKKIEQPRTPAI---PTVNLPFKN-PNQSSKPLPSNQDPTTASFVTSADLEKFRAELLQD 846
P RTP++ P P ++ P+ KP S D +F DL++ + E+L++
Sbjct: 335 PVSSILSRTPSVAKSPEAKSPLQSQPHSRMKPAGSVNDMALDAF----DLDRMKQEILEE 390
Query: 847 IVSNMEKFKEDIINGIISKLN 909
+V + K KE+II+ I +L+
Sbjct: 391 VVRELHKVKEEIIDAIRQELS 411
>sp|O08719|EVL_RAT Ena/vasodilator-stimulated phosphoprotein-like protein (Ena/VASP-like protein) Length = 393 Score = 49.7 bits (117), Expect = 1e-05 Identities = 32/120 (26%), Positives = 50/120 (41%), Gaps = 9/120 (7%) Frame = +1 Query: 1 LNSFLFASMNYTESTPTFHQWYDEGKNAYGLNFPDANEAKKFGIAVNSAIEILNGSK--- 171 +N + + Y ++TPTFHQW D + YGLNF EA F A+ A+ I+N + Sbjct: 61 INYSIVKGLKYNQATPTFHQWRD-ARQVYGLNFASKGEATTFSNAMLFALNIMNSQEGGP 119 Query: 172 ------INKPGGDNFVVPKKSVEKQPSNNPTVVSPYATAGIHQTNDSSTAKVPTLPTGKP 333 N P + + ++ V +Q ++ + G P LP G P Sbjct: 120 STQRQVQNGPSPEEMDIQRRQVMEQQHRQESLERRISATG------------PILPPGHP 167
Score = 33.5 bits (75), Expect = 1.0
Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
Frame = +1
Query: 676 PPKKIEQPRTP--AIPTVNLPFKNPNQSSKPLPSNQDPTTASFVTSADLEKFRAELLQDI 849
PP E R P +V P + KP S D + + DL++ + E+L+++
Sbjct: 313 PPNSSEAGRKPWERSNSVEKPVSSLLSRVKPAGSVNDVG----LDALDLDRMKQEILEEV 368
Query: 850 VSNMEKFKEDIINGIISKLN 909
V + K KE+II+ I +L+
Sbjct: 369 VRELHKVKEEIIDAIRQELS 388
>sp|P70429|EVL_MOUSE Ena/vasodilator-stimulated phosphoprotein-like protein (Ena/VASP-like protein) Length = 414 Score = 49.7 bits (117), Expect = 1e-05 Identities = 32/120 (26%), Positives = 50/120 (41%), Gaps = 9/120 (7%) Frame = +1 Query: 1 LNSFLFASMNYTESTPTFHQWYDEGKNAYGLNFPDANEAKKFGIAVNSAIEILNGSK--- 171 +N + + Y ++TPTFHQW D + YGLNF EA F A+ A+ I+N + Sbjct: 61 INYSIVKGLKYNQATPTFHQWRD-ARQVYGLNFASKEEATTFSNAMLFALNIMNSQEGGP 119 Query: 172 ------INKPGGDNFVVPKKSVEKQPSNNPTVVSPYATAGIHQTNDSSTAKVPTLPTGKP 333 N P + + ++ V +Q ++ + G P LP G P Sbjct: 120 STQRQVQNGPSPEEMDIQRRQVMEQQHRQESLERRISATG------------PILPPGHP 167
Score = 46.2 bits (108), Expect = 2e-04
Identities = 38/146 (26%), Positives = 66/146 (45%), Gaps = 4/146 (2%)
Frame = +1
Query: 484 LASQLRAKQETMKHTSTNSNADNISRESPTPPVQSTQSISSKPPKMDFLSEIKLKTQNRQ 663
LA + +A +T K + D E P+ +S+PP SE K R
Sbjct: 273 LAKRRKAASQTDK--PADRKEDESQTEDPSTSPSPGTRATSQPPNS---SEAGRKPWERS 327
Query: 664 DGINPPKKIEQPRTPAI---PTVNLPFKN-PNQSSKPLPSNQDPTTASFVTSADLEKFRA 831
+ + P RTP++ P P ++ P+ KP S D + + DL++ +
Sbjct: 328 NSVEKPVSSLLSRTPSVAKSPEAKSPLQSQPHSRVKPAGSVNDVG----LDALDLDRMKQ 383
Query: 832 ELLQDIVSNMEKFKEDIINGIISKLN 909
E+L+++V + K KE+II+ I +L+
Sbjct: 384 EILEEVVRELHKVKEEIIDAIRQELS 409
>sp|P50551|VASP_CANFA Vasodilator-stimulated phosphoprotein (VASP) Length = 384 Score = 49.3 bits (116), Expect = 2e-05 Identities = 22/55 (40%), Positives = 33/55 (60%) Frame = +1 Query: 1 LNSFLFASMNYTESTPTFHQWYDEGKNAYGLNFPDANEAKKFGIAVNSAIEILNG 165 +N + + Y ++TPTFHQW D + +GLNF +A +F A+ SA+E L G Sbjct: 62 INCAIVRGIKYNQATPTFHQWRD-ARQVWGLNFGSKEDATQFAAAMASALEALEG 115
Score = 41.6 bits (96), Expect = 0.004
Identities = 35/138 (25%), Positives = 60/138 (43%), Gaps = 15/138 (10%)
Frame = +1
Query: 538 SNADNISRESPTPPVQSTQSISSKPPKMDFLSEIKLKTQNRQDGINPPKKIEQPRTPA-- 711
S + S P P +ST+S + + + + + + Q G PPK P
Sbjct: 242 SKQEEASGGPPVPKAESTRSTGGGLME-EMNAMLARRRKATQVGEKPPKDESANEEPEAR 300
Query: 712 --IP----TVNLPFKNPN-------QSSKPLPSNQDPTTASFVTSADLEKFRAELLQDIV 852
+P TV P++ + SS S P+T S +DLE+ + ELL+++
Sbjct: 301 VPVPAQSETVRRPWEKNSTTLPRMKSSSSVTTSEAHPSTPSSSDESDLERVKQELLEEVR 360
Query: 853 SNMEKFKEDIINGIISKL 906
++K KE+II + +L
Sbjct: 361 KELQKVKEEIIEAFVQEL 378
>sp|P50552|VASP_HUMAN Vasodilator-stimulated phosphoprotein (VASP) Length = 380 Score = 46.6 bits (109), Expect = 1e-04 Identities = 26/78 (33%), Positives = 38/78 (48%) Frame = +1 Query: 1 LNSFLFASMNYTESTPTFHQWYDEGKNAYGLNFPDANEAKKFGIAVNSAIEILNGSKINK 180 +N + + Y ++TP FHQW D + +GLNF +A +F + SA+E L G Sbjct: 62 INCAIVRGVKYNQATPNFHQWRD-ARQVWGLNFGSKEDAAQFAAGMASALEALEGGGPPP 120 Query: 181 PGGDNFVVPKKSVEKQPS 234 P +P SV PS Sbjct: 121 PP----ALPTWSVPNGPS 134
Score = 36.6 bits (83), Expect = 0.12
Identities = 17/52 (32%), Positives = 29/52 (55%)
Frame = +1
Query: 751 SSKPLPSNQDPTTASFVTSADLEKFRAELLQDIVSNMEKFKEDIINGIISKL 906
SS S P T S +DL++ + ELL+++ ++K KE+II + +L
Sbjct: 323 SSSVTTSETQPCTPSSSDYSDLQRVKQELLEEVKKELQKVKEEIIEAFVQEL 374
>sp|Q8N8S7|ENAH_HUMAN Enabled protein homolog Length = 591 Score = 46.2 bits (108), Expect = 2e-04 Identities = 21/57 (36%), Positives = 32/57 (56%) Frame = +1 Query: 1 LNSFLFASMNYTESTPTFHQWYDEGKNAYGLNFPDANEAKKFGIAVNSAIEILNGSK 171 +N + + Y ++T TFHQW D + YGLNF +A F A+ A+E+LN + Sbjct: 60 INCAIPKGLKYNQATQTFHQWRD-ARQVYGLNFGSKEDANVFASAMMHALEVLNSQE 115
>sp|Q03173|ENAH_MOUSE Enabled protein homolog (NPC derived proline-rich protein 1) (NDPP-1) Length = 802 Score = 46.2 bits (108), Expect = 2e-04 Identities = 21/57 (36%), Positives = 32/57 (56%) Frame = +1 Query: 1 LNSFLFASMNYTESTPTFHQWYDEGKNAYGLNFPDANEAKKFGIAVNSAIEILNGSK 171 +N + + Y ++T TFHQW D + YGLNF +A F A+ A+E+LN + Sbjct: 60 INCAIPKGLKYNQATQTFHQWRD-ARQVYGLNFGSKEDANVFASAMMHALEVLNSQE 115
>sp|P70460|VASP_MOUSE Vasodilator-stimulated phosphoprotein (VASP) Length = 376 Score = 43.9 bits (102), Expect = 8e-04 Identities = 19/55 (34%), Positives = 31/55 (56%) Frame = +1 Query: 1 LNSFLFASMNYTESTPTFHQWYDEGKNAYGLNFPDANEAKKFGIAVNSAIEILNG 165 +N + + Y ++TP FHQW D + +GLNF +A +F + +A+E L G Sbjct: 62 INCAIIRGVKYNQATPIFHQWRD-ARQVWGLNFGSKEDAIQFATGMANALEALEG 115
Score = 38.1 bits (87), Expect = 0.042
Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 4/107 (3%)
Frame = +1
Query: 598 ISSKPPKMDFLS----EIKLKTQNRQDGINPPKKIEQPRTPAIPTVNLPFKNPNQSSKPL 765
+ KPPK + S E +L Q+ P ++ + + +P + SS
Sbjct: 276 VGEKPPKDESASQEESEARLPAQSE-----PVRRPWEKNSTTLPRMK-------SSSSVT 323
Query: 766 PSNQDPTTASFVTSADLEKFRAELLQDIVSNMEKFKEDIINGIISKL 906
S P+T +DLE+ + ELL+++ ++K KE+II + +L
Sbjct: 324 TSEAHPSTPCSSDDSDLERVKQELLEEVRKELQKMKEEIIEVFVQEL 370
>sp|Q924S8|Spre1_MOUSE Sprouty-related, EVH1 domain containing protein 1 (Spred-1) Length = 444 Score = 38.5 bits (88), Expect = 0.032 Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 4/69 (5%) Frame = +1 Query: 1 LNSFLFASMNYTESTPTFHQWYDEGKNAYGLNFPDANEAKKFGIAVNSAIEILN----GS 168 L L + Y + TPTFH W + K +GL F +A+ F + AIE ++ S Sbjct: 72 LECMLKKDLIYNKVTPTFHHWKIDDKK-FGLTFQSPADARAFDRGIRRAIEDISLGCPAS 130 Query: 169 KINKPGGDN 195 K GGD+ Sbjct: 131 KTEAEGGDD 139
>sp|Q6NYK3|Spre2_BRARE Sprouty-related, EVH1 domain containing protein 2 (Spred-2) Length = 413 Score = 38.5 bits (88), Expect = 0.032 Identities = 20/53 (37%), Positives = 28/53 (52%) Frame = +1 Query: 1 LNSFLFASMNYTESTPTFHQWYDEGKNAYGLNFPDANEAKKFGIAVNSAIEIL 159 L F+ + YT++TPTFH W + K GL F +A+ F V A+E L Sbjct: 71 LECFVRKDLIYTKATPTFHHWKVDNKKC-GLTFQSPADARAFDRGVRKALEDL 122
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.317 0.131 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 106,224,001
Number of Sequences: 369166
Number of extensions: 2032536
Number of successful extensions: 6532
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6067
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6485
length of database: 68,354,980
effective HSP length: 111
effective length of database: 47,849,395
effective search space used: 11196758430
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Cluster detail
