Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_G17
(872 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9UI08|EVL_HUMAN Ena/vasodilator-stimulated phosphoprote... 51 4e-06
sp|P50551|VASP_CANFA Vasodilator-stimulated phosphoprotein ... 49 1e-05
sp|O08719|EVL_RAT Ena/vasodilator-stimulated phosphoprotein... 49 1e-05
sp|P70429|EVL_MOUSE Ena/vasodilator-stimulated phosphoprote... 49 1e-05
sp|P50552|VASP_HUMAN Vasodilator-stimulated phosphoprotein ... 47 9e-05
sp|Q8N8S7|ENAH_HUMAN Enabled protein homolog 46 1e-04
sp|Q03173|ENAH_MOUSE Enabled protein homolog (NPC derived p... 46 1e-04
sp|P70460|VASP_MOUSE Vasodilator-stimulated phosphoprotein ... 44 6e-04
sp|Q924S8|Spre1_MOUSE Sprouty-related, EVH1 domain containi... 39 0.025
sp|Q6NYK3|Spre2_BRARE Sprouty-related, EVH1 domain containi... 39 0.025
>sp|Q9UI08|EVL_HUMAN Ena/vasodilator-stimulated phosphoprotein-like protein
(Ena/VASP-like protein)
Length = 416
Score = 51.2 bits (121), Expect = 4e-06
Identities = 32/109 (29%), Positives = 52/109 (47%)
Frame = +1
Query: 1 LNSFLFASMNYTESTPTFHQWYDEGKNAYGLNFPDANEAKKFGIAVNSAIEILNGSKINK 180
+N + + Y ++TPTFHQW D + YGLNF EA F A+ A+ I+N ++
Sbjct: 61 INYSIVKGLKYNQATPTFHQWRD-ARQVYGLNFASKEEATTFSNAMLFALNIMN----SQ 115
Query: 181 PGGDNFVVPKKSVEKQPSNNPTVVSPYATAGIHQTNDSSTAKVQTLPTG 327
GG + ++ V+ PS + + HQ + + +T TG
Sbjct: 116 EGGPS---SQRQVQNGPSPDEMDIQRRQVMEQHQQQRQESLERRTSATG 161
>sp|P50551|VASP_CANFA Vasodilator-stimulated phosphoprotein (VASP)
Length = 384
Score = 49.3 bits (116), Expect = 1e-05
Identities = 22/55 (40%), Positives = 33/55 (60%)
Frame = +1
Query: 1 LNSFLFASMNYTESTPTFHQWYDEGKNAYGLNFPDANEAKKFGIAVNSAIEILNG 165
+N + + Y ++TPTFHQW D + +GLNF +A +F A+ SA+E L G
Sbjct: 62 INCAIVRGIKYNQATPTFHQWRD-ARQVWGLNFGSKEDATQFAAAMASALEALEG 115
Score = 32.3 bits (72), Expect = 1.8
Identities = 32/125 (25%), Positives = 55/125 (44%), Gaps = 15/125 (12%)
Frame = +1
Query: 538 SNADNISRESPTPPVQSTQSISSKPPKMDFLSEIKLKTQNRQDGINPPKKI---EQP--R 702
S + S P P +ST+S + + + + + + Q G PPK E+P R
Sbjct: 242 SKQEEASGGPPVPKAESTRSTGGGLME-EMNAMLARRRKATQVGEKPPKDESANEEPEAR 300
Query: 703 TPA---TPTVNLPFKNPN-------QSSKPLPSNQDPTTASFVTSADLEKFRAELLQDIV 852
P + TV P++ + SS S P+T S +DLE+ + ELL+++
Sbjct: 301 VPVPAQSETVRRPWEKNSTTLPRMKSSSSVTTSEAHPSTPSSSDESDLERVKQELLEEVR 360
Query: 853 SNMEK 867
++K
Sbjct: 361 KELQK 365
>sp|O08719|EVL_RAT Ena/vasodilator-stimulated phosphoprotein-like protein
(Ena/VASP-like protein)
Length = 393
Score = 49.3 bits (116), Expect = 1e-05
Identities = 28/82 (34%), Positives = 42/82 (51%)
Frame = +1
Query: 1 LNSFLFASMNYTESTPTFHQWYDEGKNAYGLNFPDANEAKKFGIAVNSAIEILNGSKINK 180
+N + + Y ++TPTFHQW D + YGLNF EA F A+ A+ I+N ++
Sbjct: 61 INYSIVKGLKYNQATPTFHQWRD-ARQVYGLNFASKGEATTFSNAMLFALNIMN----SQ 115
Query: 181 PGGDNFVVPKKSVEKQPSNNPT 246
GG S ++Q N P+
Sbjct: 116 EGG-------PSTQRQVQNGPS 130
>sp|P70429|EVL_MOUSE Ena/vasodilator-stimulated phosphoprotein-like protein
(Ena/VASP-like protein)
Length = 414
Score = 49.3 bits (116), Expect = 1e-05
Identities = 28/82 (34%), Positives = 42/82 (51%)
Frame = +1
Query: 1 LNSFLFASMNYTESTPTFHQWYDEGKNAYGLNFPDANEAKKFGIAVNSAIEILNGSKINK 180
+N + + Y ++TPTFHQW D + YGLNF EA F A+ A+ I+N ++
Sbjct: 61 INYSIVKGLKYNQATPTFHQWRD-ARQVYGLNFASKEEATTFSNAMLFALNIMN----SQ 115
Query: 181 PGGDNFVVPKKSVEKQPSNNPT 246
GG S ++Q N P+
Sbjct: 116 EGG-------PSTQRQVQNGPS 130
>sp|P50552|VASP_HUMAN Vasodilator-stimulated phosphoprotein (VASP)
Length = 380
Score = 46.6 bits (109), Expect = 9e-05
Identities = 26/78 (33%), Positives = 38/78 (48%)
Frame = +1
Query: 1 LNSFLFASMNYTESTPTFHQWYDEGKNAYGLNFPDANEAKKFGIAVNSAIEILNGSKINK 180
+N + + Y ++TP FHQW D + +GLNF +A +F + SA+E L G
Sbjct: 62 INCAIVRGVKYNQATPNFHQWRD-ARQVWGLNFGSKEDAAQFAAGMASALEALEGGGPPP 120
Query: 181 PGGDNFVVPKKSVEKQPS 234
P +P SV PS
Sbjct: 121 PP----ALPTWSVPNGPS 134
>sp|Q8N8S7|ENAH_HUMAN Enabled protein homolog
Length = 591
Score = 46.2 bits (108), Expect = 1e-04
Identities = 21/57 (36%), Positives = 32/57 (56%)
Frame = +1
Query: 1 LNSFLFASMNYTESTPTFHQWYDEGKNAYGLNFPDANEAKKFGIAVNSAIEILNGSK 171
+N + + Y ++T TFHQW D + YGLNF +A F A+ A+E+LN +
Sbjct: 60 INCAIPKGLKYNQATQTFHQWRD-ARQVYGLNFGSKEDANVFASAMMHALEVLNSQE 115
>sp|Q03173|ENAH_MOUSE Enabled protein homolog (NPC derived proline-rich protein 1)
(NDPP-1)
Length = 802
Score = 46.2 bits (108), Expect = 1e-04
Identities = 21/57 (36%), Positives = 32/57 (56%)
Frame = +1
Query: 1 LNSFLFASMNYTESTPTFHQWYDEGKNAYGLNFPDANEAKKFGIAVNSAIEILNGSK 171
+N + + Y ++T TFHQW D + YGLNF +A F A+ A+E+LN +
Sbjct: 60 INCAIPKGLKYNQATQTFHQWRD-ARQVYGLNFGSKEDANVFASAMMHALEVLNSQE 115
>sp|P70460|VASP_MOUSE Vasodilator-stimulated phosphoprotein (VASP)
Length = 376
Score = 43.9 bits (102), Expect = 6e-04
Identities = 19/55 (34%), Positives = 31/55 (56%)
Frame = +1
Query: 1 LNSFLFASMNYTESTPTFHQWYDEGKNAYGLNFPDANEAKKFGIAVNSAIEILNG 165
+N + + Y ++TP FHQW D + +GLNF +A +F + +A+E L G
Sbjct: 62 INCAIIRGVKYNQATPIFHQWRD-ARQVWGLNFGSKEDAIQFATGMANALEALEG 115
>sp|Q924S8|Spre1_MOUSE Sprouty-related, EVH1 domain containing protein 1 (Spred-1)
Length = 444
Score = 38.5 bits (88), Expect = 0.025
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 4/69 (5%)
Frame = +1
Query: 1 LNSFLFASMNYTESTPTFHQWYDEGKNAYGLNFPDANEAKKFGIAVNSAIEILN----GS 168
L L + Y + TPTFH W + K +GL F +A+ F + AIE ++ S
Sbjct: 72 LECMLKKDLIYNKVTPTFHHWKIDDKK-FGLTFQSPADARAFDRGIRRAIEDISLGCPAS 130
Query: 169 KINKPGGDN 195
K GGD+
Sbjct: 131 KTEAEGGDD 139
>sp|Q6NYK3|Spre2_BRARE Sprouty-related, EVH1 domain containing protein 2 (Spred-2)
Length = 413
Score = 38.5 bits (88), Expect = 0.025
Identities = 20/53 (37%), Positives = 28/53 (52%)
Frame = +1
Query: 1 LNSFLFASMNYTESTPTFHQWYDEGKNAYGLNFPDANEAKKFGIAVNSAIEIL 159
L F+ + YT++TPTFH W + K GL F +A+ F V A+E L
Sbjct: 71 LECFVRKDLIYTKATPTFHHWKVDNKKC-GLTFQSPADARAFDRGVRKALEDL 122
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.307 0.124 0.347
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91,845,789
Number of Sequences: 369166
Number of extensions: 1773750
Number of successful extensions: 4944
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4531
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4886
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8646143400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)