Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00624 (1139 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q8VHI6|WASF3_MOUSE Wiskott-Aldrich syndrome protein fami... 82 4e-15 sp|Q9UPY6|WASF3_HUMAN Wiskott-Aldrich syndrome protein fami... 81 6e-15 sp|Q9Y6W5|WASF2_HUMAN Wiskott-Aldrich syndrome protein fami... 72 4e-12 sp|Q8IV90|WASF4_HUMAN Wiskott-Aldrich syndrome protein fami... 70 9e-12 sp|Q92558|WASF1_HUMAN Wiskott-Aldrich syndrome protein fami... 70 1e-11 sp|Q8R5H6|WASF1_MOUSE Wiskott-Aldrich syndrome protein fami... 70 1e-11 sp|Q8BH43|WASF2_MOUSE Wiskott-Aldrich syndrome protein fami... 64 6e-10 sp|P15935|BCNA_CLOPE Bacteriocin uviA 34 0.68 sp|Q90339|MYSS_CYPCA Myosin heavy chain, fast skeletal muscle 32 3.4 sp|O42184|REST_CHICK Restin (Cytoplasmic linker protein 170... 32 4.4
>sp|Q8VHI6|WASF3_MOUSE Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (WAVE-3 protein) Length = 501 Score = 81.6 bits (200), Expect = 4e-15 Identities = 44/149 (29%), Positives = 83/149 (55%), Gaps = 2/149 (1%) Frame = +2 Query: 50 ESVENEFEYIFNATLSNFIKQISCLTVKAKDIFDELAVSLTNIVDRSLILENKIDQLTEQ 229 E V +E E + N+TL+ I+Q+S L+ A+DIF EL N R+ L+++ID+L + Sbjct: 20 EGVTSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEANNFYIRANSLQDRIDRLAVK 79 Query: 230 IKMNDSSVLQPLVN--QQTEVYKIHLSRDDERFVQMEMPDCIREIFDKAEPPPDLFKFDE 403 + DS+V + + + +K +D + + +P+ + +I+++++ PP L Sbjct: 80 VTQLDSTVEEVSLQDINMKKAFKSSTIQDQQVVSKNSIPNPVADIYNQSDKPPPLSILTP 139 Query: 404 FRKEEGDSLKYYTDPEFFLREWLKNVRVD 490 +R ++ D LK+YTDP +F W + + D Sbjct: 140 YRDDKKDGLKFYTDPSYFFDLWKEKMLQD 168
Score = 31.6 bits (70), Expect = 4.4 Identities = 16/38 (42%), Positives = 22/38 (57%) Frame = +2 Query: 818 KPEPRAIPEPDSIQNLLRAIQQGTTLKPVTAQKEAKRK 931 +PEP P D+ +LL AI+ G LK V Q+E + K Sbjct: 428 RPEPAQPPISDARSDLLAAIRMGIQLKKVQEQREQEAK 465
>sp|Q9UPY6|WASF3_HUMAN Wiskott-Aldrich syndrome protein family member 3 (WASP-family protein member 3) (WAVE-3 protein) (Verprolin homology domain-containing protein 3) Length = 502 Score = 80.9 bits (198), Expect = 6e-15 Identities = 43/149 (28%), Positives = 83/149 (55%), Gaps = 2/149 (1%) Frame = +2 Query: 50 ESVENEFEYIFNATLSNFIKQISCLTVKAKDIFDELAVSLTNIVDRSLILENKIDQLTEQ 229 E + +E E + N+TL+ I+Q+S L+ A+DIF EL N R+ L+++ID+L + Sbjct: 20 EGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEANNFYIRANSLQDRIDRLAVK 79 Query: 230 IKMNDSSVLQPLVN--QQTEVYKIHLSRDDERFVQMEMPDCIREIFDKAEPPPDLFKFDE 403 + DS+V + + + +K +D + + +P+ + +I+++++ PP L Sbjct: 80 VTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNPVADIYNQSDKPPPLNILTP 139 Query: 404 FRKEEGDSLKYYTDPEFFLREWLKNVRVD 490 +R ++ D LK+YTDP +F W + + D Sbjct: 140 YRDDKKDGLKFYTDPSYFFDLWKEKMLQD 168
>sp|Q9Y6W5|WASF2_HUMAN Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (WAVE-2 protein) (Verprolin homology domain-containing protein 2) Length = 498 Score = 71.6 bits (174), Expect = 4e-12 Identities = 42/150 (28%), Positives = 75/150 (50%), Gaps = 4/150 (2%) Frame = +2 Query: 53 SVENEFEYIFNATLSNFIKQISCLTVKAKDIFDELAVSLTNIVDRSLILENKIDQLTEQI 232 SV +E E + N TL+N I+Q+ L+ A+DIF EL R L ++D+L Q+ Sbjct: 20 SVRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQANTFASRVSSLAERVDRL--QV 77 Query: 233 KMNDSSVLQPLVNQQ----TEVYKIHLSRDDERFVQMEMPDCIREIFDKAEPPPDLFKFD 400 K+ + V+ Q + ++ +D + F + +P + E ++ + PP L Sbjct: 78 KVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVPVLETYNTCDTPPPLNNLT 137 Query: 401 EFRKEEGDSLKYYTDPEFFLREWLKNVRVD 490 +R + ++LK+YTDP +F W + + D Sbjct: 138 PYRDDGKEALKFYTDPSYFFDLWKEKMLQD 167
>sp|Q8IV90|WASF4_HUMAN Wiskott-Aldrich syndrome protein family member 4 (WASP-family protein member 4) Length = 625 Score = 70.5 bits (171), Expect = 9e-12 Identities = 41/149 (27%), Positives = 73/149 (48%), Gaps = 3/149 (2%) Frame = +2 Query: 53 SVENEFEYIFNATLSNFIKQISCLTVKAKDIFDELAVSLTNIVDRSLILENKIDQL---T 223 SV +E E + N TL+N I+Q+ L+ A+DIF EL L ++D L Sbjct: 148 SVRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQANTFASPVSSLAERVDGLQVKV 207 Query: 224 EQIKMNDSSVLQPLVNQQTEVYKIHLSRDDERFVQMEMPDCIREIFDKAEPPPDLFKFDE 403 Q+ + V ++N + + ++ +D + F + +P + E ++ + PP L Sbjct: 208 TQLDPKEEEVSLQVINTR-KAFRSSTIQDQKLFDRNSLPVPVLETYNTCDTPPPLNNLTP 266 Query: 404 FRKEEGDSLKYYTDPEFFLREWLKNVRVD 490 +R + ++LK+YTDP +F W K + D Sbjct: 267 YRDDGTEALKFYTDPSYFFDLWKKKMLQD 295
>sp|Q92558|WASF1_HUMAN Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (WAVE-1 protein) (Verprolin homology domain-containing protein 1) Length = 559 Score = 70.1 bits (170), Expect = 1e-11 Identities = 40/147 (27%), Positives = 76/147 (51%), Gaps = 2/147 (1%) Frame = +2 Query: 56 VENEFEYIFNATLSNFIKQISCLTVKAKDIFDELAVSLTNIVDRSLILENKIDQLTEQIK 235 ++NE E + N +L+N I+Q+S L+ A+DIF EL + R L+ ++D+L+ + Sbjct: 22 IKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSFRVNSLQERVDRLSVSVT 81 Query: 236 MNDSSVLQPLVNQQT--EVYKIHLSRDDERFVQMEMPDCIREIFDKAEPPPDLFKFDEFR 409 D + + T + ++ +D + F + +P ++E +D E PP L +R Sbjct: 82 QLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIPLQETYDVCEQPPPLNILTPYR 141 Query: 410 KEEGDSLKYYTDPEFFLREWLKNVRVD 490 + + LK+YT+P +F W + + D Sbjct: 142 DDGKEGLKFYTNPSYFFDLWKEKMLQD 168
>sp|Q8R5H6|WASF1_MOUSE Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (WAVE-1 protein) Length = 559 Score = 70.1 bits (170), Expect = 1e-11 Identities = 40/147 (27%), Positives = 76/147 (51%), Gaps = 2/147 (1%) Frame = +2 Query: 56 VENEFEYIFNATLSNFIKQISCLTVKAKDIFDELAVSLTNIVDRSLILENKIDQLTEQIK 235 ++NE E + N +L+N I+Q+S L+ A+DIF EL + R L+ ++D+L+ + Sbjct: 22 IKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSFRVNSLQERVDRLSVSVT 81 Query: 236 MNDSSVLQPLVNQQT--EVYKIHLSRDDERFVQMEMPDCIREIFDKAEPPPDLFKFDEFR 409 D + + T + ++ +D + F + +P ++E +D E PP L +R Sbjct: 82 QLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIPLQETYDVCEQPPPLNILTPYR 141 Query: 410 KEEGDSLKYYTDPEFFLREWLKNVRVD 490 + + LK+YT+P +F W + + D Sbjct: 142 DDGKEGLKFYTNPSYFFDLWKEKMLQD 168
>sp|Q8BH43|WASF2_MOUSE Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (WAVE-2 protein) Length = 497 Score = 64.3 bits (155), Expect = 6e-10 Identities = 37/147 (25%), Positives = 74/147 (50%), Gaps = 4/147 (2%) Frame = +2 Query: 62 NEFEYIFNATLSNFIKQISCLTVKAKDIFDELAVSLTNIVDRSLILENKIDQLTEQIKMN 241 +E E N TL+N I+Q+ L+ A+DIF E+ + R L ++D++ Q+K+ Sbjct: 23 SELECRTNITLANVIRQLGSLSKYAEDIFGEICTQASAFASRVNSLAERVDRV--QVKVT 80 Query: 242 DSSVLQPLVNQQ----TEVYKIHLSRDDERFVQMEMPDCIREIFDKAEPPPDLFKFDEFR 409 + V+ Q + ++ ++D + F + +P + E ++ + PP L +R Sbjct: 81 QLDPKEEEVSLQGINTRKAFRSSTTQDQKLFDRNSLPVPVLETYNSCDAPPPLNNLSPYR 140 Query: 410 KEEGDSLKYYTDPEFFLREWLKNVRVD 490 + ++LK+YT+P +F W + + D Sbjct: 141 DDGKEALKFYTNPSYFFDLWKEKMLQD 167
>sp|P15935|BCNA_CLOPE Bacteriocin uviA Length = 185 Score = 34.3 bits (77), Expect = 0.68 Identities = 35/135 (25%), Positives = 66/135 (48%), Gaps = 1/135 (0%) Frame = +2 Query: 50 ESVENEFEYIFNATLSNFIKQISCLTVKAKDIFDELAVSLTNIVDRSLILENKIDQLTEQ 229 E + N FE + N +F+K+I + +D +L VSL NIV++ I + + E Sbjct: 20 EYIINRFEILINKYKMSFLKEIHFNSYDIEDNKQDLIVSLINIVNKIPIDNPQFE--NEG 77 Query: 230 IKMNDSSVLQPLVNQQTEVYKIHLSRDDER-FVQMEMPDCIREIFDKAEPPPDLFKFDEF 406 +N + + ++N + ++Y ++++ +R F++ + + E DK L K+ E Sbjct: 78 CLVN--YIYKSILNSRKDMY---INKNIKRYFIESQSLSSMVEFKDK-----PLVKYIES 127 Query: 407 RKEEGDSLKYYTDPE 451 E D LK T+ E Sbjct: 128 NIEIEDMLKCLTEKE 142
>sp|Q90339|MYSS_CYPCA Myosin heavy chain, fast skeletal muscle Length = 1935 Score = 32.0 bits (71), Expect = 3.4 Identities = 27/112 (24%), Positives = 50/112 (44%) Frame = +2 Query: 50 ESVENEFEYIFNATLSNFIKQISCLTVKAKDIFDELAVSLTNIVDRSLILENKIDQLTEQ 229 E +E+E E T + C +K KDI D+L ++L + ENK+ LTE+ Sbjct: 925 ERLEDEEEINAELTAKKRKLEDECSELK-KDI-DDLELTLAKVEKEKHATENKVKNLTEE 982 Query: 230 IKMNDSSVLQPLVNQQTEVYKIHLSRDDERFVQMEMPDCIREIFDKAEPPPD 385 + D S+ + L ++ + + H D+ + + + + + K E D Sbjct: 983 MASQDESIAK-LTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVD 1033
>sp|O42184|REST_CHICK Restin (Cytoplasmic linker protein 170) (CLIP-170) Length = 1433 Score = 31.6 bits (70), Expect = 4.4 Identities = 21/73 (28%), Positives = 41/73 (56%), Gaps = 9/73 (12%) Frame = +2 Query: 95 SNFIKQISCLTVKAKDIFDE-------LAVSLTNIVDRSLI-LENKIDQLTE-QIKMNDS 247 S +K+I L K ++ +E L L ++ D+ L+ +E+ +++L E +IK+ + Sbjct: 676 SQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKEL 735 Query: 248 SVLQPLVNQQTEV 286 VLQ N+QT++ Sbjct: 736 DVLQAKCNEQTKL 748
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 91,910,557 Number of Sequences: 369166 Number of extensions: 1493329 Number of successful extensions: 3905 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3786 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3901 length of database: 68,354,980 effective HSP length: 112 effective length of database: 47,664,660 effective search space used: 12726464220 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)