Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_J12
(854 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8VHI6|WASF3_MOUSE Wiskott-Aldrich syndrome protein fami... 82 2e-15
sp|Q9UPY6|WASF3_HUMAN Wiskott-Aldrich syndrome protein fami... 81 4e-15
sp|Q9Y6W5|WASF2_HUMAN Wiskott-Aldrich syndrome protein fami... 72 3e-12
sp|Q8IV90|WASF4_HUMAN Wiskott-Aldrich syndrome protein fami... 70 6e-12
sp|Q92558|WASF1_HUMAN Wiskott-Aldrich syndrome protein fami... 70 7e-12
sp|Q8R5H6|WASF1_MOUSE Wiskott-Aldrich syndrome protein fami... 70 7e-12
sp|Q8BH43|WASF2_MOUSE Wiskott-Aldrich syndrome protein fami... 64 4e-10
sp|P15935|BCNA_CLOPE Bacteriocin uviA 34 0.45
sp|Q90339|MYSS_CYPCA Myosin heavy chain, fast skeletal muscle 32 2.2
sp|O42184|REST_CHICK Restin (Cytoplasmic linker protein 170... 32 2.9
>sp|Q8VHI6|WASF3_MOUSE Wiskott-Aldrich syndrome protein family member 3 (WASP-family
protein member 3) (WAVE-3 protein)
Length = 501
Score = 81.6 bits (200), Expect = 2e-15
Identities = 44/149 (29%), Positives = 83/149 (55%), Gaps = 2/149 (1%)
Frame = +2
Query: 50 ESVENEFEYIFNATLSNFIKQISCLTVKAKDIFDELAVSLTNIVDRSLILENKIDQLTEQ 229
E V +E E + N+TL+ I+Q+S L+ A+DIF EL N R+ L+++ID+L +
Sbjct: 20 EGVTSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEANNFYIRANSLQDRIDRLAVK 79
Query: 230 IKMNDSSVLQPLVN--QQTEVYKIHLSRDDERFVQMEMPDCIREIFDKAEPPPDLFKFDE 403
+ DS+V + + + +K +D + + +P+ + +I+++++ PP L
Sbjct: 80 VTQLDSTVEEVSLQDINMKKAFKSSTIQDQQVVSKNSIPNPVADIYNQSDKPPPLSILTP 139
Query: 404 FRKEEGDSLKYYTDPEFFLREWLKNVRVD 490
+R ++ D LK+YTDP +F W + + D
Sbjct: 140 YRDDKKDGLKFYTDPSYFFDLWKEKMLQD 168
>sp|Q9UPY6|WASF3_HUMAN Wiskott-Aldrich syndrome protein family member 3 (WASP-family
protein member 3) (WAVE-3 protein) (Verprolin homology
domain-containing protein 3)
Length = 502
Score = 80.9 bits (198), Expect = 4e-15
Identities = 43/149 (28%), Positives = 83/149 (55%), Gaps = 2/149 (1%)
Frame = +2
Query: 50 ESVENEFEYIFNATLSNFIKQISCLTVKAKDIFDELAVSLTNIVDRSLILENKIDQLTEQ 229
E + +E E + N+TL+ I+Q+S L+ A+DIF EL N R+ L+++ID+L +
Sbjct: 20 EGITSELECVTNSTLAAIIRQLSSLSKHAEDIFGELFNEANNFYIRANSLQDRIDRLAVK 79
Query: 230 IKMNDSSVLQPLVN--QQTEVYKIHLSRDDERFVQMEMPDCIREIFDKAEPPPDLFKFDE 403
+ DS+V + + + +K +D + + +P+ + +I+++++ PP L
Sbjct: 80 VTQLDSTVEEVSLQDINMKKAFKSSTVQDQQVVSKNSIPNPVADIYNQSDKPPPLNILTP 139
Query: 404 FRKEEGDSLKYYTDPEFFLREWLKNVRVD 490
+R ++ D LK+YTDP +F W + + D
Sbjct: 140 YRDDKKDGLKFYTDPSYFFDLWKEKMLQD 168
>sp|Q9Y6W5|WASF2_HUMAN Wiskott-Aldrich syndrome protein family member 2 (WASP-family
protein member 2) (WAVE-2 protein) (Verprolin homology
domain-containing protein 2)
Length = 498
Score = 71.6 bits (174), Expect = 3e-12
Identities = 42/150 (28%), Positives = 75/150 (50%), Gaps = 4/150 (2%)
Frame = +2
Query: 53 SVENEFEYIFNATLSNFIKQISCLTVKAKDIFDELAVSLTNIVDRSLILENKIDQLTEQI 232
SV +E E + N TL+N I+Q+ L+ A+DIF EL R L ++D+L Q+
Sbjct: 20 SVRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQANTFASRVSSLAERVDRL--QV 77
Query: 233 KMNDSSVLQPLVNQQ----TEVYKIHLSRDDERFVQMEMPDCIREIFDKAEPPPDLFKFD 400
K+ + V+ Q + ++ +D + F + +P + E ++ + PP L
Sbjct: 78 KVTQLDPKEEEVSLQGINTRKAFRSSTIQDQKLFDRNSLPVPVLETYNTCDTPPPLNNLT 137
Query: 401 EFRKEEGDSLKYYTDPEFFLREWLKNVRVD 490
+R + ++LK+YTDP +F W + + D
Sbjct: 138 PYRDDGKEALKFYTDPSYFFDLWKEKMLQD 167
>sp|Q8IV90|WASF4_HUMAN Wiskott-Aldrich syndrome protein family member 4 (WASP-family
protein member 4)
Length = 625
Score = 70.5 bits (171), Expect = 6e-12
Identities = 41/149 (27%), Positives = 73/149 (48%), Gaps = 3/149 (2%)
Frame = +2
Query: 53 SVENEFEYIFNATLSNFIKQISCLTVKAKDIFDELAVSLTNIVDRSLILENKIDQL---T 223
SV +E E + N TL+N I+Q+ L+ A+DIF EL L ++D L
Sbjct: 148 SVRSELECVTNITLANVIRQLGSLSKYAEDIFGELFTQANTFASPVSSLAERVDGLQVKV 207
Query: 224 EQIKMNDSSVLQPLVNQQTEVYKIHLSRDDERFVQMEMPDCIREIFDKAEPPPDLFKFDE 403
Q+ + V ++N + + ++ +D + F + +P + E ++ + PP L
Sbjct: 208 TQLDPKEEEVSLQVINTR-KAFRSSTIQDQKLFDRNSLPVPVLETYNTCDTPPPLNNLTP 266
Query: 404 FRKEEGDSLKYYTDPEFFLREWLKNVRVD 490
+R + ++LK+YTDP +F W K + D
Sbjct: 267 YRDDGTEALKFYTDPSYFFDLWKKKMLQD 295
>sp|Q92558|WASF1_HUMAN Wiskott-Aldrich syndrome protein family member 1 (WASP-family
protein member 1) (WAVE-1 protein) (Verprolin homology
domain-containing protein 1)
Length = 559
Score = 70.1 bits (170), Expect = 7e-12
Identities = 40/147 (27%), Positives = 76/147 (51%), Gaps = 2/147 (1%)
Frame = +2
Query: 56 VENEFEYIFNATLSNFIKQISCLTVKAKDIFDELAVSLTNIVDRSLILENKIDQLTEQIK 235
++NE E + N +L+N I+Q+S L+ A+DIF EL + R L+ ++D+L+ +
Sbjct: 22 IKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSFRVNSLQERVDRLSVSVT 81
Query: 236 MNDSSVLQPLVNQQT--EVYKIHLSRDDERFVQMEMPDCIREIFDKAEPPPDLFKFDEFR 409
D + + T + ++ +D + F + +P ++E +D E PP L +R
Sbjct: 82 QLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIPLQETYDVCEQPPPLNILTPYR 141
Query: 410 KEEGDSLKYYTDPEFFLREWLKNVRVD 490
+ + LK+YT+P +F W + + D
Sbjct: 142 DDGKEGLKFYTNPSYFFDLWKEKMLQD 168
>sp|Q8R5H6|WASF1_MOUSE Wiskott-Aldrich syndrome protein family member 1 (WASP-family
protein member 1) (WAVE-1 protein)
Length = 559
Score = 70.1 bits (170), Expect = 7e-12
Identities = 40/147 (27%), Positives = 76/147 (51%), Gaps = 2/147 (1%)
Frame = +2
Query: 56 VENEFEYIFNATLSNFIKQISCLTVKAKDIFDELAVSLTNIVDRSLILENKIDQLTEQIK 235
++NE E + N +L+N I+Q+S L+ A+DIF EL + R L+ ++D+L+ +
Sbjct: 22 IKNELECVTNISLANIIRQLSSLSKYAEDIFGELFNEAHSFSFRVNSLQERVDRLSVSVT 81
Query: 236 MNDSSVLQPLVNQQT--EVYKIHLSRDDERFVQMEMPDCIREIFDKAEPPPDLFKFDEFR 409
D + + T + ++ +D + F + +P ++E +D E PP L +R
Sbjct: 82 QLDPKEEELSLQDITMRKAFRSSTIQDQQLFDRKTLPIPLQETYDVCEQPPPLNILTPYR 141
Query: 410 KEEGDSLKYYTDPEFFLREWLKNVRVD 490
+ + LK+YT+P +F W + + D
Sbjct: 142 DDGKEGLKFYTNPSYFFDLWKEKMLQD 168
>sp|Q8BH43|WASF2_MOUSE Wiskott-Aldrich syndrome protein family member 2 (WASP-family
protein member 2) (WAVE-2 protein)
Length = 497
Score = 64.3 bits (155), Expect = 4e-10
Identities = 37/147 (25%), Positives = 74/147 (50%), Gaps = 4/147 (2%)
Frame = +2
Query: 62 NEFEYIFNATLSNFIKQISCLTVKAKDIFDELAVSLTNIVDRSLILENKIDQLTEQIKMN 241
+E E N TL+N I+Q+ L+ A+DIF E+ + R L ++D++ Q+K+
Sbjct: 23 SELECRTNITLANVIRQLGSLSKYAEDIFGEICTQASAFASRVNSLAERVDRV--QVKVT 80
Query: 242 DSSVLQPLVNQQ----TEVYKIHLSRDDERFVQMEMPDCIREIFDKAEPPPDLFKFDEFR 409
+ V+ Q + ++ ++D + F + +P + E ++ + PP L +R
Sbjct: 81 QLDPKEEEVSLQGINTRKAFRSSTTQDQKLFDRNSLPVPVLETYNSCDAPPPLNNLSPYR 140
Query: 410 KEEGDSLKYYTDPEFFLREWLKNVRVD 490
+ ++LK+YT+P +F W + + D
Sbjct: 141 DDGKEALKFYTNPSYFFDLWKEKMLQD 167
>sp|P15935|BCNA_CLOPE Bacteriocin uviA
Length = 185
Score = 34.3 bits (77), Expect = 0.45
Identities = 35/135 (25%), Positives = 66/135 (48%), Gaps = 1/135 (0%)
Frame = +2
Query: 50 ESVENEFEYIFNATLSNFIKQISCLTVKAKDIFDELAVSLTNIVDRSLILENKIDQLTEQ 229
E + N FE + N +F+K+I + +D +L VSL NIV++ I + + E
Sbjct: 20 EYIINRFEILINKYKMSFLKEIHFNSYDIEDNKQDLIVSLINIVNKIPIDNPQFE--NEG 77
Query: 230 IKMNDSSVLQPLVNQQTEVYKIHLSRDDER-FVQMEMPDCIREIFDKAEPPPDLFKFDEF 406
+N + + ++N + ++Y ++++ +R F++ + + E DK L K+ E
Sbjct: 78 CLVN--YIYKSILNSRKDMY---INKNIKRYFIESQSLSSMVEFKDK-----PLVKYIES 127
Query: 407 RKEEGDSLKYYTDPE 451
E D LK T+ E
Sbjct: 128 NIEIEDMLKCLTEKE 142
>sp|Q90339|MYSS_CYPCA Myosin heavy chain, fast skeletal muscle
Length = 1935
Score = 32.0 bits (71), Expect = 2.2
Identities = 27/112 (24%), Positives = 50/112 (44%)
Frame = +2
Query: 50 ESVENEFEYIFNATLSNFIKQISCLTVKAKDIFDELAVSLTNIVDRSLILENKIDQLTEQ 229
E +E+E E T + C +K KDI D+L ++L + ENK+ LTE+
Sbjct: 925 ERLEDEEEINAELTAKKRKLEDECSELK-KDI-DDLELTLAKVEKEKHATENKVKNLTEE 982
Query: 230 IKMNDSSVLQPLVNQQTEVYKIHLSRDDERFVQMEMPDCIREIFDKAEPPPD 385
+ D S+ + L ++ + + H D+ + + + + + K E D
Sbjct: 983 MASQDESIAK-LTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVD 1033
>sp|O42184|REST_CHICK Restin (Cytoplasmic linker protein 170) (CLIP-170)
Length = 1433
Score = 31.6 bits (70), Expect = 2.9
Identities = 21/73 (28%), Positives = 41/73 (56%), Gaps = 9/73 (12%)
Frame = +2
Query: 95 SNFIKQISCLTVKAKDIFDE-------LAVSLTNIVDRSLI-LENKIDQLTE-QIKMNDS 247
S +K+I L K ++ +E L L ++ D+ L+ +E+ +++L E +IK+ +
Sbjct: 676 SQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKEL 735
Query: 248 SVLQPLVNQQTEV 286
VLQ N+QT++
Sbjct: 736 DVLQAKCNEQTKL 748
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,893,603
Number of Sequences: 369166
Number of extensions: 1079667
Number of successful extensions: 2945
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2874
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2941
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8438301375
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)