Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00554 (821 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9H444|CHM4B_HUMAN Charged multivesicular body protein 4... 177 3e-44 sp|Q9D8B3|CHM4B_MOUSE Charged multivesicular body protein 4... 177 4e-44 sp|Q5XGW6|CHM4B_XENLA Charged multivesicular body protein 4... 174 2e-43 sp|Q6GL11|CHM4B_XENTR Charged multivesicular body protein 4... 174 3e-43 sp|Q7ZVC4|CHM4B_BRARE Charged multivesicular body protein 4... 173 4e-43 sp|Q5ZHP5|CHM4B_CHICK Charged multivesicular body protein 4... 172 1e-42 sp|Q6IQ73|CHM4C_BRARE Charged multivesicular body protein 4... 171 2e-42 sp|Q9BY43|CHM4A_HUMAN Charged multivesicular body protein 4... 169 1e-41 sp|Q6GNN8|CHM4C_XENLA Charged multivesicular body protein 4... 163 5e-40 sp|Q96CF2|CHM4C_HUMAN Charged multivesicular body protein 4... 148 2e-35
>sp|Q9H444|CHM4B_HUMAN Charged multivesicular body protein 4b (Chromatin modifying protein 4b) (CHMP4b) (Vacuolar protein sorting 7-2) (SNF7-2) (hSnf7-2) (SNF7 homolog associated with Alix 1) (hVps32) Length = 224 Score = 177 bits (449), Expect = 3e-44 Identities = 98/200 (49%), Positives = 124/200 (62%), Gaps = 3/200 (1%) Frame = +1 Query: 31 FKMSFASFFGKKKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXX 210 F F + GK K TPQEAIQ+L+ ++ML KKQ+FLEKKIEQEL+ AKKHGT Sbjct: 4 FGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKR 63 Query: 211 XXXXXXXXXXXYEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNM 390 YEKQL QIDGTL+T+EFQ EALENA+TNTEVLK M A++++KAAH NM Sbjct: 64 AALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNM 123 Query: 391 DVDKVHDVMDEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXXXXNALLDV 570 D+DKV ++M +I +QQELA+EI+ A+S PVGFG LL++ Sbjct: 124 DIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEI 183 Query: 571 GGRNA---NTEPTLGLPSAP 621 G P++ LPS P Sbjct: 184 SGPETVPLPNVPSIALPSKP 203
>sp|Q9D8B3|CHM4B_MOUSE Charged multivesicular body protein 4b (Chromatin modifying protein 4b) (CHMP4b) Length = 224 Score = 177 bits (448), Expect = 4e-44 Identities = 98/200 (49%), Positives = 124/200 (62%), Gaps = 3/200 (1%) Frame = +1 Query: 31 FKMSFASFFGKKKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXX 210 F F + GK K TPQEAIQ+L+ ++ML KKQ+FLEKKIEQEL+ AKKHGT Sbjct: 4 FGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKR 63 Query: 211 XXXXXXXXXXXYEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNM 390 YEKQL QIDGTL+T+EFQ EALENA+TNTEVLK M A++++KAAH NM Sbjct: 64 AALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNM 123 Query: 391 DVDKVHDVMDEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXXXXNALLDV 570 D+DKV ++M +I +QQELA+EI+ A+S PVGFG LL++ Sbjct: 124 DIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEI 183 Query: 571 GGRNA---NTEPTLGLPSAP 621 G P++ LPS P Sbjct: 184 SGPETVPLPNVPSVALPSKP 203
>sp|Q5XGW6|CHM4B_XENLA Charged multivesicular body protein 4b (Chromatin modifying protein 4b) (CHMP4b) Length = 222 Score = 174 bits (442), Expect = 2e-43 Identities = 97/192 (50%), Positives = 122/192 (63%) Frame = +1 Query: 58 GKKKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXXXXXXXXX 237 G K + +PQEAIQKL+ ++ML KKQ+FLEKKIEQEL TAKKHGT Sbjct: 11 GGKGAKGPSPQEAIQKLRDTEEMLAKKQEFLEKKIEQELVTAKKHGTKNKRAALQALKRK 70 Query: 238 XXYEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDVDKVHDVM 417 YEKQL QIDGTL+T+EFQ EALENA+TNTEVLK M A++++KAAH NMD++KV ++M Sbjct: 71 KRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHDNMDIEKVDELM 130 Query: 418 DEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXXXXNALLDVGGRNANTEP 597 +I +QQELA+EI+DA+S PVGFG LL+V G Sbjct: 131 QDIADQQELAQEISDAISKPVGFGEDFDEDELMAELEELEQEELDKNLLEVQG-----PE 185 Query: 598 TLGLPSAPQHEL 633 T+ LP+ P L Sbjct: 186 TVPLPNVPAASL 197
>sp|Q6GL11|CHM4B_XENTR Charged multivesicular body protein 4b (Chromatin modifying protein 4b) (CHMP4b) Length = 222 Score = 174 bits (441), Expect = 3e-43 Identities = 96/187 (51%), Positives = 121/187 (64%) Frame = +1 Query: 58 GKKKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXXXXXXXXX 237 G K + +PQEAIQKL+ ++ML KKQ+FLEKKIEQEL TAKKHGT Sbjct: 11 GGKGAKGPSPQEAIQKLRDTEEMLTKKQEFLEKKIEQELVTAKKHGTKNKRAALQALKRK 70 Query: 238 XXYEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDVDKVHDVM 417 YEKQL QIDGTL+T+EFQ EALENA+TNTEVLK M A++++KAAH NMD++KV ++M Sbjct: 71 KRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHDNMDIEKVDELM 130 Query: 418 DEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXXXXNALLDVGGRNANTEP 597 +I +QQELA+EI+DA+S PVGFG LL+V G T P Sbjct: 131 QDIADQQELAQEISDAISKPVGFGEDFDEDELMAELEELEQEELDKNLLEVQG--PETVP 188 Query: 598 TLGLPSA 618 +P+A Sbjct: 189 LPNVPAA 195
>sp|Q7ZVC4|CHM4B_BRARE Charged multivesicular body protein 4b (Chromatin modifying protein 4b) (CHMP4b) Length = 220 Score = 173 bits (439), Expect = 4e-43 Identities = 98/196 (50%), Positives = 123/196 (62%), Gaps = 3/196 (1%) Frame = +1 Query: 43 FASFFGKKKK--ESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXX 216 F FG K +S +PQEAIQ+L+ ++ML KKQ+FLEKKIEQEL TAKK+GT Sbjct: 4 FGKMFGSGGKGGKSASPQEAIQRLRETEEMLTKKQEFLEKKIEQELVTAKKNGTKNKRAA 63 Query: 217 XXXXXXXXXYEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDV 396 YEKQL QIDGTL+T+EFQ EALENA TNTEV+K M A++++KAAH NMD+ Sbjct: 64 LQALKRKKRYEKQLAQIDGTLSTIEFQREALENAHTNTEVIKNMGYAAKAMKAAHDNMDI 123 Query: 397 DKVHDVMDEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXXXXNALLDVGG 576 DKV ++M +I EQQELA+EI+DA+S PVGFG LL++G Sbjct: 124 DKVDELMQDIIEQQELAQEISDAISKPVGFGEEFDEDELLAELEELEQEELDKNLLEIGD 183 Query: 577 R-NANTEPTLGLPSAP 621 P+ LPS P Sbjct: 184 NVPLPNVPSTSLPSRP 199
>sp|Q5ZHP5|CHM4B_CHICK Charged multivesicular body protein 4b (Chromatin modifying protein 4b) (CHMP4b) Length = 227 Score = 172 bits (436), Expect = 1e-42 Identities = 95/199 (47%), Positives = 123/199 (61%), Gaps = 3/199 (1%) Frame = +1 Query: 34 KMSFASFFGKKKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXX 213 K+ A GK + +PQEAIQ+L+ ++ML KKQ+FLEKKIEQEL+ A+KHGT Sbjct: 7 KLFGAGAGGKGAGKGPSPQEAIQRLRDTEEMLSKKQEFLEKKIEQELAAARKHGTKNKRA 66 Query: 214 XXXXXXXXXXYEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMD 393 YEKQL QIDGTL+T+EFQ EALENA+TNTEVLK M A++++KAAH NMD Sbjct: 67 ALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHDNMD 126 Query: 394 VDKVHDVMDEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXXXXNALLDVG 573 +DKV ++M +I EQQELA EI+ A+S PVGFG LL++ Sbjct: 127 IDKVDELMQDIAEQQELADEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEIS 186 Query: 574 GRNA---NTEPTLGLPSAP 621 G P++ +PS P Sbjct: 187 GPETVPLPNVPSISIPSKP 205
>sp|Q6IQ73|CHM4C_BRARE Charged multivesicular body protein 4c (Chromatin modifying protein 4c) (CHMP4c) Length = 224 Score = 171 bits (433), Expect = 2e-42 Identities = 88/144 (61%), Positives = 108/144 (75%) Frame = +1 Query: 58 GKKKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXXXXXXXXX 237 G K + TPQEAIQKL+ ++ML KKQDFLEKKI+ EL AKK+GT Sbjct: 11 GGKGGKGPTPQEAIQKLRETEEMLAKKQDFLEKKIDAELLIAKKNGTKNKRAALQALKRK 70 Query: 238 XXYEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDVDKVHDVM 417 YEKQL QIDGTL+T+EFQ EALENA+TNTEVLK M A++++K AH+NMD+DKV D+M Sbjct: 71 KRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKTAHENMDIDKVDDLM 130 Query: 418 DEIQEQQELAKEIADAVSNPVGFG 489 +I EQQELA+EI+DA+S PVGFG Sbjct: 131 QDITEQQELAQEISDAISRPVGFG 154
>sp|Q9BY43|CHM4A_HUMAN Charged multivesicular body protein 4a (Chromatin modifying protein 4a) (CHMP4a) (Vacuolar protein sorting 7-1) (SNF7-1) (hSnf-1) (SNF7 homolog associated with Alix 2) Length = 222 Score = 169 bits (427), Expect = 1e-41 Identities = 92/194 (47%), Positives = 127/194 (65%), Gaps = 1/194 (0%) Frame = +1 Query: 55 FGKKKKES-ETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXXXXXXX 231 FGK KKE TP+EAIQKLK + +L+KKQ+FLE+KI+QEL TAKK+GT Sbjct: 8 FGKGKKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALR 67 Query: 232 XXXXYEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDVDKVHD 411 +E+QL Q DGTL+T+EFQ EA+ENA+TN EVL+ M++A+QS+K A+Q+MD+DKV + Sbjct: 68 RKKRFEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDE 127 Query: 412 VMDEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXXXXNALLDVGGRNANT 591 +M +I EQQE+A++I+DA+S P+GF LL+VG + Sbjct: 128 LMTDITEQQEVAQQISDAISRPMGFRDDVDEDELLEELEELEQEELAQELLNVGDK--EE 185 Query: 592 EPTLGLPSAPQHEL 633 EP++ LPS P L Sbjct: 186 EPSVKLPSVPSTHL 199
>sp|Q6GNN8|CHM4C_XENLA Charged multivesicular body protein 4c (Chromatin modifying protein 4c) (CHMP4c) Length = 227 Score = 163 bits (413), Expect = 5e-40 Identities = 83/153 (54%), Positives = 111/153 (72%) Frame = +1 Query: 31 FKMSFASFFGKKKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXX 210 FK S S K ++ + QEA+ KL+ ++ML KKQ++LEKKIE EL+TAKKHGT Sbjct: 8 FKSSGGSGSSSKNRKGPSAQEALFKLRETEEMLTKKQEYLEKKIELELATAKKHGTKNKR 67 Query: 211 XXXXXXXXXXXYEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNM 390 EKQL QIDGTL+T+EFQ EALEN+ TNTEVLK M A++++KAAH+NM Sbjct: 68 AALQALKKKKRLEKQLAQIDGTLSTIEFQREALENSHTNTEVLKNMGYAAKAMKAAHENM 127 Query: 391 DVDKVHDVMDEIQEQQELAKEIADAVSNPVGFG 489 D++K+ D+M +I EQQ++A+EI+DA+S PVGFG Sbjct: 128 DLEKIDDLMQDIHEQQDVAQEISDAISRPVGFG 160
>sp|Q96CF2|CHM4C_HUMAN Charged multivesicular body protein 4c (Chromatin modifying protein 4c) (CHMP4c) (Vacuolar protein sorting 7-3) (SNF7-3) (hSnf7-3) (SNF7 homolog associated with Alix 3) Length = 233 Score = 148 bits (373), Expect = 2e-35 Identities = 71/142 (50%), Positives = 106/142 (74%) Frame = +1 Query: 64 KKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXXXXXXXXXXX 243 K + + +PQEA+ +L+ ++ML KKQ++LE +I++E++ AKKHGT Sbjct: 15 KSRAAPSPQEALVRLRETEEMLGKKQEYLENRIQREIALAKKHGTQNKRAALQALKRKKR 74 Query: 244 YEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDVDKVHDVMDE 423 +EKQLTQIDGTL+T+EFQ EALEN+ TNTEVL+ M A++++K+ H+NMD++K+ D+M E Sbjct: 75 FEKQLTQIDGTLSTIEFQREALENSHTNTEVLRNMGFAAKAMKSVHENMDLNKIDDLMQE 134 Query: 424 IQEQQELAKEIADAVSNPVGFG 489 I EQQ++A+EI++A S VGFG Sbjct: 135 ITEQQDIAQEISEAFSQRVGFG 156
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 71,572,868 Number of Sequences: 369166 Number of extensions: 1136663 Number of successful extensions: 3209 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3088 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3202 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 7907893860 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)