Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_D04
(699 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9H444|CHM4B_HUMAN Charged multivesicular body protein 4... 173 3e-43
sp|Q9D8B3|CHM4B_MOUSE Charged multivesicular body protein 4... 173 4e-43
sp|Q5XGW6|CHM4B_XENLA Charged multivesicular body protein 4... 173 4e-43
sp|Q6GL11|CHM4B_XENTR Charged multivesicular body protein 4... 172 6e-43
sp|Q7ZVC4|CHM4B_BRARE Charged multivesicular body protein 4... 171 1e-42
sp|Q5ZHP5|CHM4B_CHICK Charged multivesicular body protein 4... 169 5e-42
sp|Q6IQ73|CHM4C_BRARE Charged multivesicular body protein 4... 169 5e-42
sp|Q9BY43|CHM4A_HUMAN Charged multivesicular body protein 4... 166 4e-41
sp|Q6GNN8|CHM4C_XENLA Charged multivesicular body protein 4... 159 5e-39
sp|Q96CF2|CHM4C_HUMAN Charged multivesicular body protein 4... 148 2e-35
>sp|Q9H444|CHM4B_HUMAN Charged multivesicular body protein 4b (Chromatin modifying protein
4b) (CHMP4b) (Vacuolar protein sorting 7-2) (SNF7-2)
(hSnf7-2) (SNF7 homolog associated with Alix 1) (hVps32)
Length = 224
Score = 173 bits (439), Expect = 3e-43
Identities = 94/187 (50%), Positives = 119/187 (63%), Gaps = 3/187 (1%)
Frame = +1
Query: 10 KESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXXXXXXXXXXXYE 189
K TPQEAIQ+L+ ++ML KKQ+FLEKKIEQEL+ AKKHGT YE
Sbjct: 17 KGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYE 76
Query: 190 KQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDVDKVHDVMDEIQ 369
KQL QIDGTL+T+EFQ EALENA+TNTEVLK M A++++KAAH NMD+DKV ++M +I
Sbjct: 77 KQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMDIDKVDELMQDIA 136
Query: 370 EQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXXXXNALLDVGGRNA---NTEPT 540
+QQELA+EI+ A+S PVGFG LL++ G P+
Sbjct: 137 DQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEISGPETVPLPNVPS 196
Query: 541 LGLPSAP 561
+ LPS P
Sbjct: 197 IALPSKP 203
>sp|Q9D8B3|CHM4B_MOUSE Charged multivesicular body protein 4b (Chromatin modifying protein
4b) (CHMP4b)
Length = 224
Score = 173 bits (438), Expect = 4e-43
Identities = 94/187 (50%), Positives = 119/187 (63%), Gaps = 3/187 (1%)
Frame = +1
Query: 10 KESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXXXXXXXXXXXYE 189
K TPQEAIQ+L+ ++ML KKQ+FLEKKIEQEL+ AKKHGT YE
Sbjct: 17 KGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRAALQALKRKKRYE 76
Query: 190 KQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDVDKVHDVMDEIQ 369
KQL QIDGTL+T+EFQ EALENA+TNTEVLK M A++++KAAH NMD+DKV ++M +I
Sbjct: 77 KQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNMDIDKVDELMQDIA 136
Query: 370 EQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXXXXNALLDVGGRNA---NTEPT 540
+QQELA+EI+ A+S PVGFG LL++ G P+
Sbjct: 137 DQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEISGPETVPLPNVPS 196
Query: 541 LGLPSAP 561
+ LPS P
Sbjct: 197 VALPSKP 203
>sp|Q5XGW6|CHM4B_XENLA Charged multivesicular body protein 4b (Chromatin modifying protein
4b) (CHMP4b)
Length = 222
Score = 173 bits (438), Expect = 4e-43
Identities = 96/190 (50%), Positives = 121/190 (63%)
Frame = +1
Query: 4 KKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXXXXXXXXXXX 183
K + +PQEAIQKL+ ++ML KKQ+FLEKKIEQEL TAKKHGT
Sbjct: 13 KGAKGPSPQEAIQKLRDTEEMLAKKQEFLEKKIEQELVTAKKHGTKNKRAALQALKRKKR 72
Query: 184 YEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDVDKVHDVMDE 363
YEKQL QIDGTL+T+EFQ EALENA+TNTEVLK M A++++KAAH NMD++KV ++M +
Sbjct: 73 YEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHDNMDIEKVDELMQD 132
Query: 364 IQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXXXXNALLDVGGRNANTEPTL 543
I +QQELA+EI+DA+S PVGFG LL+V G T+
Sbjct: 133 IADQQELAQEISDAISKPVGFGEDFDEDELMAELEELEQEELDKNLLEVQG-----PETV 187
Query: 544 GLPSAPQHEL 573
LP+ P L
Sbjct: 188 PLPNVPAASL 197
>sp|Q6GL11|CHM4B_XENTR Charged multivesicular body protein 4b (Chromatin modifying protein
4b) (CHMP4b)
Length = 222
Score = 172 bits (437), Expect = 6e-43
Identities = 95/185 (51%), Positives = 120/185 (64%)
Frame = +1
Query: 4 KKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXXXXXXXXXXX 183
K + +PQEAIQKL+ ++ML KKQ+FLEKKIEQEL TAKKHGT
Sbjct: 13 KGAKGPSPQEAIQKLRDTEEMLTKKQEFLEKKIEQELVTAKKHGTKNKRAALQALKRKKR 72
Query: 184 YEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDVDKVHDVMDE 363
YEKQL QIDGTL+T+EFQ EALENA+TNTEVLK M A++++KAAH NMD++KV ++M +
Sbjct: 73 YEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHDNMDIEKVDELMQD 132
Query: 364 IQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXXXXNALLDVGGRNANTEPTL 543
I +QQELA+EI+DA+S PVGFG LL+V G T P
Sbjct: 133 IADQQELAQEISDAISKPVGFGEDFDEDELMAELEELEQEELDKNLLEVQG--PETVPLP 190
Query: 544 GLPSA 558
+P+A
Sbjct: 191 NVPAA 195
>sp|Q7ZVC4|CHM4B_BRARE Charged multivesicular body protein 4b (Chromatin modifying protein
4b) (CHMP4b)
Length = 220
Score = 171 bits (434), Expect = 1e-42
Identities = 95/187 (50%), Positives = 120/187 (64%), Gaps = 1/187 (0%)
Frame = +1
Query: 4 KKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXXXXXXXXXXX 183
K +S +PQEAIQ+L+ ++ML KKQ+FLEKKIEQEL TAKK+GT
Sbjct: 13 KGGKSASPQEAIQRLRETEEMLTKKQEFLEKKIEQELVTAKKNGTKNKRAALQALKRKKR 72
Query: 184 YEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDVDKVHDVMDE 363
YEKQL QIDGTL+T+EFQ EALENA TNTEV+K M A++++KAAH NMD+DKV ++M +
Sbjct: 73 YEKQLAQIDGTLSTIEFQREALENAHTNTEVIKNMGYAAKAMKAAHDNMDIDKVDELMQD 132
Query: 364 IQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXXXXNALLDVGGR-NANTEPT 540
I EQQELA+EI+DA+S PVGFG LL++G P+
Sbjct: 133 IIEQQELAQEISDAISKPVGFGEEFDEDELLAELEELEQEELDKNLLEIGDNVPLPNVPS 192
Query: 541 LGLPSAP 561
LPS P
Sbjct: 193 TSLPSRP 199
>sp|Q5ZHP5|CHM4B_CHICK Charged multivesicular body protein 4b (Chromatin modifying protein
4b) (CHMP4b)
Length = 227
Score = 169 bits (429), Expect = 5e-42
Identities = 91/183 (49%), Positives = 117/183 (63%), Gaps = 3/183 (1%)
Frame = +1
Query: 22 TPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXXXXXXXXXXXYEKQLT 201
+PQEAIQ+L+ ++ML KKQ+FLEKKIEQEL+ A+KHGT YEKQL
Sbjct: 23 SPQEAIQRLRDTEEMLSKKQEFLEKKIEQELAAARKHGTKNKRAALQALKRKKRYEKQLA 82
Query: 202 QIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDVDKVHDVMDEIQEQQE 381
QIDGTL+T+EFQ EALENA+TNTEVLK M A++++KAAH NMD+DKV ++M +I EQQE
Sbjct: 83 QIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHDNMDIDKVDELMQDIAEQQE 142
Query: 382 LAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXXXXNALLDVGGRNA---NTEPTLGLP 552
LA EI+ A+S PVGFG LL++ G P++ +P
Sbjct: 143 LADEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEISGPETVPLPNVPSISIP 202
Query: 553 SAP 561
S P
Sbjct: 203 SKP 205
>sp|Q6IQ73|CHM4C_BRARE Charged multivesicular body protein 4c (Chromatin modifying protein
4c) (CHMP4c)
Length = 224
Score = 169 bits (429), Expect = 5e-42
Identities = 87/142 (61%), Positives = 107/142 (75%)
Frame = +1
Query: 4 KKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXXXXXXXXXXX 183
K + TPQEAIQKL+ ++ML KKQDFLEKKI+ EL AKK+GT
Sbjct: 13 KGGKGPTPQEAIQKLRETEEMLAKKQDFLEKKIDAELLIAKKNGTKNKRAALQALKRKKR 72
Query: 184 YEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDVDKVHDVMDE 363
YEKQL QIDGTL+T+EFQ EALENA+TNTEVLK M A++++K AH+NMD+DKV D+M +
Sbjct: 73 YEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKTAHENMDIDKVDDLMQD 132
Query: 364 IQEQQELAKEIADAVSNPVGFG 429
I EQQELA+EI+DA+S PVGFG
Sbjct: 133 ITEQQELAQEISDAISRPVGFG 154
>sp|Q9BY43|CHM4A_HUMAN Charged multivesicular body protein 4a (Chromatin modifying protein
4a) (CHMP4a) (Vacuolar protein sorting 7-1) (SNF7-1)
(hSnf-1) (SNF7 homolog associated with Alix 2)
Length = 222
Score = 166 bits (421), Expect = 4e-41
Identities = 88/190 (46%), Positives = 125/190 (65%)
Frame = +1
Query: 4 KKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXXXXXXXXXXX 183
KK++ TP+EAIQKLK + +L+KKQ+FLE+KI+QEL TAKK+GT
Sbjct: 12 KKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALRRKKR 71
Query: 184 YEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDVDKVHDVMDE 363
+E+QL Q DGTL+T+EFQ EA+ENA+TN EVL+ M++A+QS+K A+Q+MD+DKV ++M +
Sbjct: 72 FEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDELMTD 131
Query: 364 IQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXXXXNALLDVGGRNANTEPTL 543
I EQQE+A++I+DA+S P+GF LL+VG + EP++
Sbjct: 132 ITEQQEVAQQISDAISRPMGFRDDVDEDELLEELEELEQEELAQELLNVGDK--EEEPSV 189
Query: 544 GLPSAPQHEL 573
LPS P L
Sbjct: 190 KLPSVPSTHL 199
>sp|Q6GNN8|CHM4C_XENLA Charged multivesicular body protein 4c (Chromatin modifying protein
4c) (CHMP4c)
Length = 227
Score = 159 bits (403), Expect = 5e-39
Identities = 79/142 (55%), Positives = 107/142 (75%)
Frame = +1
Query: 4 KKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXXXXXXXXXXX 183
K ++ + QEA+ KL+ ++ML KKQ++LEKKIE EL+TAKKHGT
Sbjct: 19 KNRKGPSAQEALFKLRETEEMLTKKQEYLEKKIELELATAKKHGTKNKRAALQALKKKKR 78
Query: 184 YEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDVDKVHDVMDE 363
EKQL QIDGTL+T+EFQ EALEN+ TNTEVLK M A++++KAAH+NMD++K+ D+M +
Sbjct: 79 LEKQLAQIDGTLSTIEFQREALENSHTNTEVLKNMGYAAKAMKAAHENMDLEKIDDLMQD 138
Query: 364 IQEQQELAKEIADAVSNPVGFG 429
I EQQ++A+EI+DA+S PVGFG
Sbjct: 139 IHEQQDVAQEISDAISRPVGFG 160
>sp|Q96CF2|CHM4C_HUMAN Charged multivesicular body protein 4c (Chromatin modifying protein
4c) (CHMP4c) (Vacuolar protein sorting 7-3) (SNF7-3)
(hSnf7-3) (SNF7 homolog associated with Alix 3)
Length = 233
Score = 148 bits (373), Expect = 2e-35
Identities = 71/142 (50%), Positives = 106/142 (74%)
Frame = +1
Query: 4 KKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXXXXXXXXXXX 183
K + + +PQEA+ +L+ ++ML KKQ++LE +I++E++ AKKHGT
Sbjct: 15 KSRAAPSPQEALVRLRETEEMLGKKQEYLENRIQREIALAKKHGTQNKRAALQALKRKKR 74
Query: 184 YEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDVDKVHDVMDE 363
+EKQLTQIDGTL+T+EFQ EALEN+ TNTEVL+ M A++++K+ H+NMD++K+ D+M E
Sbjct: 75 FEKQLTQIDGTLSTIEFQREALENSHTNTEVLRNMGFAAKAMKSVHENMDLNKIDDLMQE 134
Query: 364 IQEQQELAKEIADAVSNPVGFG 429
I EQQ++A+EI++A S VGFG
Sbjct: 135 ITEQQDIAQEISEAFSQRVGFG 156
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,096,344
Number of Sequences: 369166
Number of extensions: 934492
Number of successful extensions: 2471
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2393
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2465
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6073541875
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)