Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_014_G08
(759 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9H444|CHM4B_HUMAN Charged multivesicular body protein 4... 177 3e-44
sp|Q9D8B3|CHM4B_MOUSE Charged multivesicular body protein 4... 177 4e-44
sp|Q5XGW6|CHM4B_XENLA Charged multivesicular body protein 4... 174 2e-43
sp|Q6GL11|CHM4B_XENTR Charged multivesicular body protein 4... 174 2e-43
sp|Q7ZVC4|CHM4B_BRARE Charged multivesicular body protein 4... 173 4e-43
sp|Q5ZHP5|CHM4B_CHICK Charged multivesicular body protein 4... 172 9e-43
sp|Q6IQ73|CHM4C_BRARE Charged multivesicular body protein 4... 171 2e-42
sp|Q9BY43|CHM4A_HUMAN Charged multivesicular body protein 4... 169 1e-41
sp|Q6GNN8|CHM4C_XENLA Charged multivesicular body protein 4... 163 4e-40
sp|Q96CF2|CHM4C_HUMAN Charged multivesicular body protein 4... 148 2e-35
>sp|Q9H444|CHM4B_HUMAN Charged multivesicular body protein 4b (Chromatin modifying protein
4b) (CHMP4b) (Vacuolar protein sorting 7-2) (SNF7-2)
(hSnf7-2) (SNF7 homolog associated with Alix 1) (hVps32)
Length = 224
Score = 177 bits (449), Expect = 3e-44
Identities = 98/200 (49%), Positives = 124/200 (62%), Gaps = 3/200 (1%)
Frame = +1
Query: 31 FKMSFASFFGKKKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXX 210
F F + GK K TPQEAIQ+L+ ++ML KKQ+FLEKKIEQEL+ AKKHGT
Sbjct: 4 FGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKR 63
Query: 211 XXXXXXXXXXXYEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNM 390
YEKQL QIDGTL+T+EFQ EALENA+TNTEVLK M A++++KAAH NM
Sbjct: 64 AALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNM 123
Query: 391 DVDKVHDVMDEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXXXXNALLDV 570
D+DKV ++M +I +QQELA+EI+ A+S PVGFG LL++
Sbjct: 124 DIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEI 183
Query: 571 GGRNA---NTEPTLGLPSAP 621
G P++ LPS P
Sbjct: 184 SGPETVPLPNVPSIALPSKP 203
>sp|Q9D8B3|CHM4B_MOUSE Charged multivesicular body protein 4b (Chromatin modifying protein
4b) (CHMP4b)
Length = 224
Score = 177 bits (448), Expect = 4e-44
Identities = 98/200 (49%), Positives = 124/200 (62%), Gaps = 3/200 (1%)
Frame = +1
Query: 31 FKMSFASFFGKKKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXX 210
F F + GK K TPQEAIQ+L+ ++ML KKQ+FLEKKIEQEL+ AKKHGT
Sbjct: 4 FGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKR 63
Query: 211 XXXXXXXXXXXYEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNM 390
YEKQL QIDGTL+T+EFQ EALENA+TNTEVLK M A++++KAAH NM
Sbjct: 64 AALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKAMKAAHDNM 123
Query: 391 DVDKVHDVMDEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXXXXNALLDV 570
D+DKV ++M +I +QQELA+EI+ A+S PVGFG LL++
Sbjct: 124 DIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEI 183
Query: 571 GGRNA---NTEPTLGLPSAP 621
G P++ LPS P
Sbjct: 184 SGPETVPLPNVPSVALPSKP 203
>sp|Q5XGW6|CHM4B_XENLA Charged multivesicular body protein 4b (Chromatin modifying protein
4b) (CHMP4b)
Length = 222
Score = 174 bits (442), Expect = 2e-43
Identities = 97/192 (50%), Positives = 122/192 (63%)
Frame = +1
Query: 58 GKKKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXXXXXXXXX 237
G K + +PQEAIQKL+ ++ML KKQ+FLEKKIEQEL TAKKHGT
Sbjct: 11 GGKGAKGPSPQEAIQKLRDTEEMLAKKQEFLEKKIEQELVTAKKHGTKNKRAALQALKRK 70
Query: 238 XXYEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDVDKVHDVM 417
YEKQL QIDGTL+T+EFQ EALENA+TNTEVLK M A++++KAAH NMD++KV ++M
Sbjct: 71 KRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHDNMDIEKVDELM 130
Query: 418 DEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXXXXNALLDVGGRNANTEP 597
+I +QQELA+EI+DA+S PVGFG LL+V G
Sbjct: 131 QDIADQQELAQEISDAISKPVGFGEDFDEDELMAELEELEQEELDKNLLEVQG-----PE 185
Query: 598 TLGLPSAPQHEL 633
T+ LP+ P L
Sbjct: 186 TVPLPNVPAASL 197
>sp|Q6GL11|CHM4B_XENTR Charged multivesicular body protein 4b (Chromatin modifying protein
4b) (CHMP4b)
Length = 222
Score = 174 bits (441), Expect = 2e-43
Identities = 96/187 (51%), Positives = 121/187 (64%)
Frame = +1
Query: 58 GKKKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXXXXXXXXX 237
G K + +PQEAIQKL+ ++ML KKQ+FLEKKIEQEL TAKKHGT
Sbjct: 11 GGKGAKGPSPQEAIQKLRDTEEMLTKKQEFLEKKIEQELVTAKKHGTKNKRAALQALKRK 70
Query: 238 XXYEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDVDKVHDVM 417
YEKQL QIDGTL+T+EFQ EALENA+TNTEVLK M A++++KAAH NMD++KV ++M
Sbjct: 71 KRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHDNMDIEKVDELM 130
Query: 418 DEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXXXXNALLDVGGRNANTEP 597
+I +QQELA+EI+DA+S PVGFG LL+V G T P
Sbjct: 131 QDIADQQELAQEISDAISKPVGFGEDFDEDELMAELEELEQEELDKNLLEVQG--PETVP 188
Query: 598 TLGLPSA 618
+P+A
Sbjct: 189 LPNVPAA 195
>sp|Q7ZVC4|CHM4B_BRARE Charged multivesicular body protein 4b (Chromatin modifying protein
4b) (CHMP4b)
Length = 220
Score = 173 bits (439), Expect = 4e-43
Identities = 98/196 (50%), Positives = 123/196 (62%), Gaps = 3/196 (1%)
Frame = +1
Query: 43 FASFFGKKKK--ESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXX 216
F FG K +S +PQEAIQ+L+ ++ML KKQ+FLEKKIEQEL TAKK+GT
Sbjct: 4 FGKMFGSGGKGGKSASPQEAIQRLRETEEMLTKKQEFLEKKIEQELVTAKKNGTKNKRAA 63
Query: 217 XXXXXXXXXYEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDV 396
YEKQL QIDGTL+T+EFQ EALENA TNTEV+K M A++++KAAH NMD+
Sbjct: 64 LQALKRKKRYEKQLAQIDGTLSTIEFQREALENAHTNTEVIKNMGYAAKAMKAAHDNMDI 123
Query: 397 DKVHDVMDEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXXXXNALLDVGG 576
DKV ++M +I EQQELA+EI+DA+S PVGFG LL++G
Sbjct: 124 DKVDELMQDIIEQQELAQEISDAISKPVGFGEEFDEDELLAELEELEQEELDKNLLEIGD 183
Query: 577 R-NANTEPTLGLPSAP 621
P+ LPS P
Sbjct: 184 NVPLPNVPSTSLPSRP 199
>sp|Q5ZHP5|CHM4B_CHICK Charged multivesicular body protein 4b (Chromatin modifying protein
4b) (CHMP4b)
Length = 227
Score = 172 bits (436), Expect = 9e-43
Identities = 95/199 (47%), Positives = 123/199 (61%), Gaps = 3/199 (1%)
Frame = +1
Query: 34 KMSFASFFGKKKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXX 213
K+ A GK + +PQEAIQ+L+ ++ML KKQ+FLEKKIEQEL+ A+KHGT
Sbjct: 7 KLFGAGAGGKGAGKGPSPQEAIQRLRDTEEMLSKKQEFLEKKIEQELAAARKHGTKNKRA 66
Query: 214 XXXXXXXXXXYEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMD 393
YEKQL QIDGTL+T+EFQ EALENA+TNTEVLK M A++++KAAH NMD
Sbjct: 67 ALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHDNMD 126
Query: 394 VDKVHDVMDEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXXXXNALLDVG 573
+DKV ++M +I EQQELA EI+ A+S PVGFG LL++
Sbjct: 127 IDKVDELMQDIAEQQELADEISTAISKPVGFGEEFDEDELMAELEELEQEELDKNLLEIS 186
Query: 574 GRNA---NTEPTLGLPSAP 621
G P++ +PS P
Sbjct: 187 GPETVPLPNVPSISIPSKP 205
>sp|Q6IQ73|CHM4C_BRARE Charged multivesicular body protein 4c (Chromatin modifying protein
4c) (CHMP4c)
Length = 224
Score = 171 bits (433), Expect = 2e-42
Identities = 88/144 (61%), Positives = 108/144 (75%)
Frame = +1
Query: 58 GKKKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXXXXXXXXX 237
G K + TPQEAIQKL+ ++ML KKQDFLEKKI+ EL AKK+GT
Sbjct: 11 GGKGGKGPTPQEAIQKLRETEEMLAKKQDFLEKKIDAELLIAKKNGTKNKRAALQALKRK 70
Query: 238 XXYEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDVDKVHDVM 417
YEKQL QIDGTL+T+EFQ EALENA+TNTEVLK M A++++K AH+NMD+DKV D+M
Sbjct: 71 KRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKTAHENMDIDKVDDLM 130
Query: 418 DEIQEQQELAKEIADAVSNPVGFG 489
+I EQQELA+EI+DA+S PVGFG
Sbjct: 131 QDITEQQELAQEISDAISRPVGFG 154
>sp|Q9BY43|CHM4A_HUMAN Charged multivesicular body protein 4a (Chromatin modifying protein
4a) (CHMP4a) (Vacuolar protein sorting 7-1) (SNF7-1)
(hSnf-1) (SNF7 homolog associated with Alix 2)
Length = 222
Score = 169 bits (427), Expect = 1e-41
Identities = 92/194 (47%), Positives = 127/194 (65%), Gaps = 1/194 (0%)
Frame = +1
Query: 55 FGKKKKES-ETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXXXXXXX 231
FGK KKE TP+EAIQKLK + +L+KKQ+FLE+KI+QEL TAKK+GT
Sbjct: 8 FGKGKKEKGPTPEEAIQKLKETEKILIKKQEFLEQKIQQELQTAKKYGTKNKRAALQALR 67
Query: 232 XXXXYEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDVDKVHD 411
+E+QL Q DGTL+T+EFQ EA+ENA+TN EVL+ M++A+QS+K A+Q+MD+DKV +
Sbjct: 68 RKKRFEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQSMKKAYQDMDIDKVDE 127
Query: 412 VMDEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXXXXNALLDVGGRNANT 591
+M +I EQQE+A++I+DA+S P+GF LL+VG +
Sbjct: 128 LMTDITEQQEVAQQISDAISRPMGFRDDVDEDELLEELEELEQEELAQELLNVGDK--EE 185
Query: 592 EPTLGLPSAPQHEL 633
EP++ LPS P L
Sbjct: 186 EPSVKLPSVPSTHL 199
>sp|Q6GNN8|CHM4C_XENLA Charged multivesicular body protein 4c (Chromatin modifying protein
4c) (CHMP4c)
Length = 227
Score = 163 bits (413), Expect = 4e-40
Identities = 83/153 (54%), Positives = 111/153 (72%)
Frame = +1
Query: 31 FKMSFASFFGKKKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXX 210
FK S S K ++ + QEA+ KL+ ++ML KKQ++LEKKIE EL+TAKKHGT
Sbjct: 8 FKSSGGSGSSSKNRKGPSAQEALFKLRETEEMLTKKQEYLEKKIELELATAKKHGTKNKR 67
Query: 211 XXXXXXXXXXXYEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNM 390
EKQL QIDGTL+T+EFQ EALEN+ TNTEVLK M A++++KAAH+NM
Sbjct: 68 AALQALKKKKRLEKQLAQIDGTLSTIEFQREALENSHTNTEVLKNMGYAAKAMKAAHENM 127
Query: 391 DVDKVHDVMDEIQEQQELAKEIADAVSNPVGFG 489
D++K+ D+M +I EQQ++A+EI+DA+S PVGFG
Sbjct: 128 DLEKIDDLMQDIHEQQDVAQEISDAISRPVGFG 160
>sp|Q96CF2|CHM4C_HUMAN Charged multivesicular body protein 4c (Chromatin modifying protein
4c) (CHMP4c) (Vacuolar protein sorting 7-3) (SNF7-3)
(hSnf7-3) (SNF7 homolog associated with Alix 3)
Length = 233
Score = 148 bits (373), Expect = 2e-35
Identities = 71/142 (50%), Positives = 106/142 (74%)
Frame = +1
Query: 64 KKKESETPQEAIQKLKGIQDMLLKKQDFLEKKIEQELSTAKKHGTXXXXXXXXXXXXXXX 243
K + + +PQEA+ +L+ ++ML KKQ++LE +I++E++ AKKHGT
Sbjct: 15 KSRAAPSPQEALVRLRETEEMLGKKQEYLENRIQREIALAKKHGTQNKRAALQALKRKKR 74
Query: 244 YEKQLTQIDGTLTTVEFQVEALENASTNTEVLKAMQVASQSLKAAHQNMDVDKVHDVMDE 423
+EKQLTQIDGTL+T+EFQ EALEN+ TNTEVL+ M A++++K+ H+NMD++K+ D+M E
Sbjct: 75 FEKQLTQIDGTLSTIEFQREALENSHTNTEVLRNMGFAAKAMKSVHENMDLNKIDDLMQE 134
Query: 424 IQEQQELAKEIADAVSNPVGFG 489
I EQQ++A+EI++A S VGFG
Sbjct: 135 ITEQQDIAQEISEAFSQRVGFG 156
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,452,275
Number of Sequences: 369166
Number of extensions: 991321
Number of successful extensions: 2868
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2757
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2861
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6970118400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)