Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_H16
(637 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9H444|CHM4B_HUMAN Charged multivesicular body protein 4... 120 3e-27
sp|Q9D8B3|CHM4B_MOUSE Charged multivesicular body protein 4... 120 4e-27
sp|Q5ZHP5|CHM4B_CHICK Charged multivesicular body protein 4... 120 4e-27
sp|Q6IQ73|CHM4C_BRARE Charged multivesicular body protein 4... 119 6e-27
sp|Q5XGW6|CHM4B_XENLA Charged multivesicular body protein 4... 119 6e-27
sp|Q6GL11|CHM4B_XENTR Charged multivesicular body protein 4... 119 8e-27
sp|Q7ZVC4|CHM4B_BRARE Charged multivesicular body protein 4... 118 1e-26
sp|P59074|CG301_HUMAN Hypothetical protein CGI-301 115 9e-26
sp|Q6GNN8|CHM4C_XENLA Charged multivesicular body protein 4... 114 3e-25
sp|Q9BY43|CHM4A_HUMAN Charged multivesicular body protein 4... 111 1e-24
>sp|Q9H444|CHM4B_HUMAN Charged multivesicular body protein 4b (Chromatin modifying protein
4b) (CHMP4b) (Vacuolar protein sorting 7-2) (SNF7-2)
(hSnf7-2) (SNF7 homolog associated with Alix 1) (hVps32)
Length = 224
Score = 120 bits (301), Expect = 3e-27
Identities = 67/148 (45%), Positives = 86/148 (58%), Gaps = 3/148 (2%)
Frame = +3
Query: 3 KHGTXXXXXXXXXXXXXXXYEKQLTQIDGTLTTVEF*VEALENASTNTEVLKAMQVASQS 182
KHGT YEKQL QIDGTL+T+EF EALENA+TNTEVLK M A+++
Sbjct: 56 KHGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKA 115
Query: 183 LKAAHQNMDVDKVHDVMDEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXX 362
+KAAH NMD+DKV ++M +I +QQELA+EI+ A+S PVGFG
Sbjct: 116 MKAAHDNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEE 175
Query: 363 XXNALLDVGGRNA---NTEPTLGLPSAP 437
LL++ G P++ LPS P
Sbjct: 176 LDKNLLEISGPETVPLPNVPSIALPSKP 203
>sp|Q9D8B3|CHM4B_MOUSE Charged multivesicular body protein 4b (Chromatin modifying protein
4b) (CHMP4b)
Length = 224
Score = 120 bits (300), Expect = 4e-27
Identities = 67/148 (45%), Positives = 86/148 (58%), Gaps = 3/148 (2%)
Frame = +3
Query: 3 KHGTXXXXXXXXXXXXXXXYEKQLTQIDGTLTTVEF*VEALENASTNTEVLKAMQVASQS 182
KHGT YEKQL QIDGTL+T+EF EALENA+TNTEVLK M A+++
Sbjct: 56 KHGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGYAAKA 115
Query: 183 LKAAHQNMDVDKVHDVMDEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXX 362
+KAAH NMD+DKV ++M +I +QQELA+EI+ A+S PVGFG
Sbjct: 116 MKAAHDNMDIDKVDELMQDIADQQELAEEISTAISKPVGFGEEFDEDELMAELEELEQEE 175
Query: 363 XXNALLDVGGRNA---NTEPTLGLPSAP 437
LL++ G P++ LPS P
Sbjct: 176 LDKNLLEISGPETVPLPNVPSVALPSKP 203
>sp|Q5ZHP5|CHM4B_CHICK Charged multivesicular body protein 4b (Chromatin modifying protein
4b) (CHMP4b)
Length = 227
Score = 120 bits (300), Expect = 4e-27
Identities = 67/148 (45%), Positives = 85/148 (57%), Gaps = 3/148 (2%)
Frame = +3
Query: 3 KHGTXXXXXXXXXXXXXXXYEKQLTQIDGTLTTVEF*VEALENASTNTEVLKAMQVASQS 182
KHGT YEKQL QIDGTL+T+EF EALENA+TNTEVLK M A+++
Sbjct: 58 KHGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKA 117
Query: 183 LKAAHQNMDVDKVHDVMDEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXX 362
+KAAH NMD+DKV ++M +I EQQELA EI+ A+S PVGFG
Sbjct: 118 MKAAHDNMDIDKVDELMQDIAEQQELADEISTAISKPVGFGEEFDEDELMAELEELEQEE 177
Query: 363 XXNALLDVGGRNA---NTEPTLGLPSAP 437
LL++ G P++ +PS P
Sbjct: 178 LDKNLLEISGPETVPLPNVPSISIPSKP 205
>sp|Q6IQ73|CHM4C_BRARE Charged multivesicular body protein 4c (Chromatin modifying protein
4c) (CHMP4c)
Length = 224
Score = 119 bits (298), Expect = 6e-27
Identities = 60/101 (59%), Positives = 75/101 (74%)
Frame = +3
Query: 3 KHGTXXXXXXXXXXXXXXXYEKQLTQIDGTLTTVEF*VEALENASTNTEVLKAMQVASQS 182
K+GT YEKQL QIDGTL+T+EF EALENA+TNTEVLK M A+++
Sbjct: 54 KNGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKA 113
Query: 183 LKAAHQNMDVDKVHDVMDEIQEQQELAKEIADAVSNPVGFG 305
+K AH+NMD+DKV D+M +I EQQELA+EI+DA+S PVGFG
Sbjct: 114 MKTAHENMDIDKVDDLMQDITEQQELAQEISDAISRPVGFG 154
>sp|Q5XGW6|CHM4B_XENLA Charged multivesicular body protein 4b (Chromatin modifying protein
4b) (CHMP4b)
Length = 222
Score = 119 bits (298), Expect = 6e-27
Identities = 68/149 (45%), Positives = 87/149 (58%)
Frame = +3
Query: 3 KHGTXXXXXXXXXXXXXXXYEKQLTQIDGTLTTVEF*VEALENASTNTEVLKAMQVASQS 182
KHGT YEKQL QIDGTL+T+EF EALENA+TNTEVLK M A+++
Sbjct: 54 KHGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKA 113
Query: 183 LKAAHQNMDVDKVHDVMDEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXX 362
+KAAH NMD++KV ++M +I +QQELA+EI+DA+S PVGFG
Sbjct: 114 MKAAHDNMDIEKVDELMQDIADQQELAQEISDAISKPVGFGEDFDEDELMAELEELEQEE 173
Query: 363 XXNALLDVGGRNANTEPTLGLPSAPQHEL 449
LL+V G T+ LP+ P L
Sbjct: 174 LDKNLLEVQG-----PETVPLPNVPAASL 197
>sp|Q6GL11|CHM4B_XENTR Charged multivesicular body protein 4b (Chromatin modifying protein
4b) (CHMP4b)
Length = 222
Score = 119 bits (297), Expect = 8e-27
Identities = 67/144 (46%), Positives = 86/144 (59%)
Frame = +3
Query: 3 KHGTXXXXXXXXXXXXXXXYEKQLTQIDGTLTTVEF*VEALENASTNTEVLKAMQVASQS 182
KHGT YEKQL QIDGTL+T+EF EALENA+TNTEVLK M A+++
Sbjct: 54 KHGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKA 113
Query: 183 LKAAHQNMDVDKVHDVMDEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXX 362
+KAAH NMD++KV ++M +I +QQELA+EI+DA+S PVGFG
Sbjct: 114 MKAAHDNMDIEKVDELMQDIADQQELAQEISDAISKPVGFGEDFDEDELMAELEELEQEE 173
Query: 363 XXNALLDVGGRNANTEPTLGLPSA 434
LL+V G T P +P+A
Sbjct: 174 LDKNLLEVQG--PETVPLPNVPAA 195
>sp|Q7ZVC4|CHM4B_BRARE Charged multivesicular body protein 4b (Chromatin modifying protein
4b) (CHMP4b)
Length = 220
Score = 118 bits (295), Expect = 1e-26
Identities = 67/146 (45%), Positives = 85/146 (58%), Gaps = 1/146 (0%)
Frame = +3
Query: 3 KHGTXXXXXXXXXXXXXXXYEKQLTQIDGTLTTVEF*VEALENASTNTEVLKAMQVASQS 182
K+GT YEKQL QIDGTL+T+EF EALENA TNTEV+K M A+++
Sbjct: 54 KNGTKNKRAALQALKRKKRYEKQLAQIDGTLSTIEFQREALENAHTNTEVIKNMGYAAKA 113
Query: 183 LKAAHQNMDVDKVHDVMDEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXX 362
+KAAH NMD+DKV ++M +I EQQELA+EI+DA+S PVGFG
Sbjct: 114 MKAAHDNMDIDKVDELMQDIIEQQELAQEISDAISKPVGFGEEFDEDELLAELEELEQEE 173
Query: 363 XXNALLDVGGR-NANTEPTLGLPSAP 437
LL++G P+ LPS P
Sbjct: 174 LDKNLLEIGDNVPLPNVPSTSLPSRP 199
>sp|P59074|CG301_HUMAN Hypothetical protein CGI-301
Length = 171
Score = 115 bits (288), Expect = 9e-26
Identities = 65/148 (43%), Positives = 84/148 (56%), Gaps = 3/148 (2%)
Frame = +3
Query: 3 KHGTXXXXXXXXXXXXXXXYEKQLTQIDGTLTTVEF*VEALENASTNTEVLKAMQVASQS 182
+HGT YEKQL QIDGTL+T+EF +ALENA+TNTEVLK M A+++
Sbjct: 16 RHGTKNKPAALQALKRKKRYEKQLAQIDGTLSTIEFQQQALENANTNTEVLKNMGSAAKA 75
Query: 183 LKAAHQNMDVDKVHDVMDEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXX 362
KAAH NMD+DKV ++M +I +QQEL +EI+ A+S PVGFG
Sbjct: 76 KKAAHDNMDIDKVDELMQDIADQQELGEEISTAISKPVGFGEKSDEDELMAELEELEQEE 135
Query: 363 XXNALLDVGGRNA---NTEPTLGLPSAP 437
LL+V G P++ LPS P
Sbjct: 136 PDKNLLEVSGPETVPLPNVPSIALPSKP 163
>sp|Q6GNN8|CHM4C_XENLA Charged multivesicular body protein 4c (Chromatin modifying protein
4c) (CHMP4c)
Length = 227
Score = 114 bits (284), Expect = 3e-25
Identities = 56/101 (55%), Positives = 74/101 (73%)
Frame = +3
Query: 3 KHGTXXXXXXXXXXXXXXXYEKQLTQIDGTLTTVEF*VEALENASTNTEVLKAMQVASQS 182
KHGT EKQL QIDGTL+T+EF EALEN+ TNTEVLK M A+++
Sbjct: 60 KHGTKNKRAALQALKKKKRLEKQLAQIDGTLSTIEFQREALENSHTNTEVLKNMGYAAKA 119
Query: 183 LKAAHQNMDVDKVHDVMDEIQEQQELAKEIADAVSNPVGFG 305
+KAAH+NMD++K+ D+M +I EQQ++A+EI+DA+S PVGFG
Sbjct: 120 MKAAHENMDLEKIDDLMQDIHEQQDVAQEISDAISRPVGFG 160
>sp|Q9BY43|CHM4A_HUMAN Charged multivesicular body protein 4a (Chromatin modifying protein
4a) (CHMP4a) (Vacuolar protein sorting 7-1) (SNF7-1)
(hSnf-1) (SNF7 homolog associated with Alix 2)
Length = 222
Score = 111 bits (278), Expect = 1e-24
Identities = 61/149 (40%), Positives = 89/149 (59%)
Frame = +3
Query: 3 KHGTXXXXXXXXXXXXXXXYEKQLTQIDGTLTTVEF*VEALENASTNTEVLKAMQVASQS 182
K+GT +E+QL Q DGTL+T+EF EA+ENA+TN EVL+ M++A+QS
Sbjct: 53 KYGTKNKRAALQALRRKKRFEQQLAQTDGTLSTLEFQREAIENATTNAEVLRTMELAAQS 112
Query: 183 LKAAHQNMDVDKVHDVMDEIQEQQELAKEIADAVSNPVGFGHXXXXXXXXXXXXXXXXXX 362
+K A+Q+MD+DKV ++M +I EQQE+A++I+DA+S P+GF
Sbjct: 113 MKKAYQDMDIDKVDELMTDITEQQEVAQQISDAISRPMGFRDDVDEDELLEELEELEQEE 172
Query: 363 XXNALLDVGGRNANTEPTLGLPSAPQHEL 449
LL+VG + EP++ LPS P L
Sbjct: 173 LAQELLNVGDK--EEEPSVKLPSVPSTHL 199
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,997,379
Number of Sequences: 369166
Number of extensions: 810538
Number of successful extensions: 1797
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1771
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1797
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5121172350
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)