Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00503 (756 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q7ZW25|CHM2A_BRARE Charged multivesicular body protein 2... 232 9e-61 sp|Q6DFS6|CHM2A_XENTR Charged multivesicular body protein 2... 231 2e-60 sp|Q6IP52|CHM2A_XENLA Charged multivesicular body protein 2... 230 3e-60 sp|Q9DB34|CHM2A_MOUSE Charged multivesicular body protein 2... 228 1e-59 sp|O43633|CHM2A_HUMAN Charged multivesicular body protein 2... 228 1e-59 sp|Q5ZHN1|CHM2A_CHICK Charged multivesicular body protein 2... 218 1e-56 sp|O14177|YDS1_SCHPO Hypothetical protein C4F8.01 in chromo... 141 2e-33 sp|Q6NXD2|CHM2B_BRARE Charged multivesicular body protein 2... 115 2e-25 sp|Q5F3A2|CHM2B_CHICK Charged multivesicular body protein 2... 112 1e-24 sp|Q9UQN3|CHM2B_HUMAN Charged multivesicular body protein 2... 111 2e-24
>sp|Q7ZW25|CHM2A_BRARE Charged multivesicular body protein 2a (Chromatin modifying protein 2a) (CHMP2a) Length = 220 Score = 232 bits (591), Expect = 9e-61 Identities = 115/177 (64%), Positives = 144/177 (81%) Frame = +2 Query: 2 MKENQRALNKTIRELEREKSRLENEEKKVINDIKKMAKQGQMDAVKIMAKDLVRTRNYVK 181 +++NQRALN+ +R+L+RE+ RLE +EKK+I DIKKMAKQGQMDAVKIMAKDLVRTR YVK Sbjct: 15 LRQNQRALNRAMRDLDRERQRLEQQEKKIIADIKKMAKQGQMDAVKIMAKDLVRTRRYVK 74 Query: 182 KFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQKIMMEFERESN 361 KFI+M+ANIQAVSLKIQTL+S N+MAQAMKGVT+ M MN+ + LPQ+QKIMMEFER+S Sbjct: 75 KFIMMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMATMNRQLKLPQIQKIMMEFERQSE 134 Query: 362 IMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNIDPSKDSIGI 532 IM+MKEEMM D IDDA+ +V QVLDELG+ ++D LSN+ + S+ + Sbjct: 135 IMDMKEEMMNDAIDDAMGDEDDEEESDAVVSQVLDELGLTLSDELSNLPATGGSLSV 191
>sp|Q6DFS6|CHM2A_XENTR Charged multivesicular body protein 2a (Chromatin modifying protein 2a) (CHMP2a) Length = 220 Score = 231 bits (588), Expect = 2e-60 Identities = 114/177 (64%), Positives = 143/177 (80%) Frame = +2 Query: 2 MKENQRALNKTIRELEREKSRLENEEKKVINDIKKMAKQGQMDAVKIMAKDLVRTRNYVK 181 +++NQRALNK +RE++RE+ +LE +EKK+I DIKKMAKQGQMDAVKIMAKDLVRTR YVK Sbjct: 15 LRQNQRALNKAMREMDRERQKLEQQEKKIIADIKKMAKQGQMDAVKIMAKDLVRTRRYVK 74 Query: 182 KFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQKIMMEFERESN 361 KFI+M+ANIQAVSLKIQTL+S N+MAQAMKGVT+ M MN+ + LPQ+QKIMMEFE++S Sbjct: 75 KFIMMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMATMNRQLKLPQIQKIMMEFEKQSE 134 Query: 362 IMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNIDPSKDSIGI 532 IM+MKEEMM D IDDA+ +V QVLDELG+ + D LSN+ + S+ + Sbjct: 135 IMDMKEEMMNDAIDDAMGDEDDEEESDAVVSQVLDELGLTLTDELSNLPSTGGSLSV 191
>sp|Q6IP52|CHM2A_XENLA Charged multivesicular body protein 2a (Chromatin modifying protein 2a) (CHMP2a) Length = 220 Score = 230 bits (587), Expect = 3e-60 Identities = 114/177 (64%), Positives = 143/177 (80%) Frame = +2 Query: 2 MKENQRALNKTIRELEREKSRLENEEKKVINDIKKMAKQGQMDAVKIMAKDLVRTRNYVK 181 +++NQRALN+ +REL+RE+ +LE +EKK+I DIKKMAKQGQMDAVKIMAKDLVRTR YVK Sbjct: 15 LRQNQRALNRAMRELDRERQKLEQQEKKIIADIKKMAKQGQMDAVKIMAKDLVRTRRYVK 74 Query: 182 KFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQKIMMEFERESN 361 KFI+M+ANIQAVSLKIQTL+S N+MAQAMKGVT+ M MN+ + LPQ+QKIMMEFE++S Sbjct: 75 KFIMMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMATMNRQLKLPQIQKIMMEFEKQSE 134 Query: 362 IMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNIDPSKDSIGI 532 IM+MKEEMM D IDDA+ +V QVLDELG+ + D LSN+ + S+ + Sbjct: 135 IMDMKEEMMNDAIDDAMGDEDDEEESDAVVSQVLDELGLTLTDELSNLPSTGGSLSV 191
>sp|Q9DB34|CHM2A_MOUSE Charged multivesicular body protein 2a (Chromatin modifying protein 2a) (CHMP2a) (Vacuolar protein sorting 2) (mVps2) Length = 222 Score = 228 bits (582), Expect = 1e-59 Identities = 112/177 (63%), Positives = 143/177 (80%) Frame = +2 Query: 2 MKENQRALNKTIRELEREKSRLENEEKKVINDIKKMAKQGQMDAVKIMAKDLVRTRNYVK 181 +++NQRALN+ +REL+RE+ +LE +EKK+I DIKKMAKQGQMDAV+IMAKDLVRTR YV+ Sbjct: 15 LRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVR 74 Query: 182 KFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQKIMMEFERESN 361 KF+LM+ANIQAVSLKIQTL+S N+MAQAMKGVT+ M MN+ + LPQ+QKIMMEFER++ Sbjct: 75 KFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFERQAE 134 Query: 362 IMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNIDPSKDSIGI 532 IM+MKEEMM D IDDA+ +V QVLDELG+ + D LSN+ + S+ + Sbjct: 135 IMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLPSTGGSLSV 191
>sp|O43633|CHM2A_HUMAN Charged multivesicular body protein 2a (Chromatin modifying protein 2a) (CHMP2a) (Vacuolar protein sorting 2-1) (Vps2-1) (hVps2-1) (Putative breast adenocarcinoma marker BC-2) Length = 222 Score = 228 bits (582), Expect = 1e-59 Identities = 112/177 (63%), Positives = 143/177 (80%) Frame = +2 Query: 2 MKENQRALNKTIRELEREKSRLENEEKKVINDIKKMAKQGQMDAVKIMAKDLVRTRNYVK 181 +++NQRALN+ +REL+RE+ +LE +EKK+I DIKKMAKQGQMDAV+IMAKDLVRTR YV+ Sbjct: 15 LRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVR 74 Query: 182 KFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQKIMMEFERESN 361 KF+LM+ANIQAVSLKIQTL+S N+MAQAMKGVT+ M MN+ + LPQ+QKIMMEFER++ Sbjct: 75 KFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFERQAE 134 Query: 362 IMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNIDPSKDSIGI 532 IM+MKEEMM D IDDA+ +V QVLDELG+ + D LSN+ + S+ + Sbjct: 135 IMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLPSTGGSLSV 191
>sp|Q5ZHN1|CHM2A_CHICK Charged multivesicular body protein 2a (Chromatin modifying protein 2a) (CHMP2a) Length = 220 Score = 218 bits (556), Expect = 1e-56 Identities = 108/175 (61%), Positives = 138/175 (78%) Frame = +2 Query: 2 MKENQRALNKTIRELEREKSRLENEEKKVINDIKKMAKQGQMDAVKIMAKDLVRTRNYVK 181 +++NQRAL + +REL+RE+ +LE +EKK+I DIKKMAKQGQMDAVKIMAKDLVRTR YVK Sbjct: 15 LRQNQRALTRAMRELDRERQKLEAQEKKIIIDIKKMAKQGQMDAVKIMAKDLVRTRRYVK 74 Query: 182 KFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQKIMMEFERESN 361 KFI M+AN+QAVSLKIQTL+S N+MA AMKGVT+ M MN+ + LPQ+QKIMMEFE+++ Sbjct: 75 KFITMRANVQAVSLKIQTLKSNNSMALAMKGVTKAMATMNRQLKLPQIQKIMMEFEKQAG 134 Query: 362 IMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNIDPSKDSI 526 IM+MKEE+M D IDDA+ +V QVLDELG+ + D L+ + P S+ Sbjct: 135 IMDMKEELMNDAIDDAMGDEDDEEESDAVVSQVLDELGLNLTDELATLPPPGGSL 189
>sp|O14177|YDS1_SCHPO Hypothetical protein C4F8.01 in chromosome I Length = 210 Score = 141 bits (356), Expect = 2e-33 Identities = 69/165 (41%), Positives = 113/165 (68%) Frame = +2 Query: 2 MKENQRALNKTIRELEREKSRLENEEKKVINDIKKMAKQGQMDAVKIMAKDLVRTRNYVK 181 ++ +QR+L + REL+RE+++L+ E+ +I +IK AK G A +I A+DL+R RN K Sbjct: 18 LRAHQRSLGRAERELDRERTKLDQRERALIQEIKGSAKAGNTGAARIQARDLMRLRNSRK 77 Query: 182 KFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQKIMMEFERESN 361 K + K +QA+SL++QT+R++ M Q+M+G TR + MNKSMN+P + +I +FERE+ Sbjct: 78 KMMNAKTQLQAISLRLQTMRTSEQMMQSMRGATRLLTGMNKSMNIPAMARITQQFERENE 137 Query: 362 IMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTL 496 IME ++EM+ + +DDAL +LV +VLDE+G++++ L Sbjct: 138 IMEQRQEMIDENMDDAL-EEDDEEEADELVNKVLDEIGVDLSQGL 181
>sp|Q6NXD2|CHM2B_BRARE Charged multivesicular body protein 2b (Chromatin modifying protein 2b) (CHMP2b) Length = 214 Score = 115 bits (287), Expect = 2e-25 Identities = 59/167 (35%), Positives = 100/167 (59%) Frame = +2 Query: 2 MKENQRALNKTIRELEREKSRLENEEKKVINDIKKMAKQGQMDAVKIMAKDLVRTRNYVK 181 +KE + L T R++ R+++ LE +EK++ +IKKMAK G DA K++AK LV+ R Sbjct: 14 IKEQNKELRGTQRQIARDRTALEKQEKQLEMEIKKMAKTGNRDACKVLAKQLVQVRKQKT 73 Query: 182 KFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQKIMMEFERESN 361 + + + + ++S + + + S MA AM T+TMQ +NK M+ + + + F++E+ Sbjct: 74 RTYAVSSKVTSMSTQTKLMNSQMKMAGAMATTTKTMQAVNKKMDPKKTMQTLQNFQKETA 133 Query: 362 IMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSN 502 M+M EEMM DT+D+ +V QVLDE+GIEI+ +++ Sbjct: 134 KMDMTEEMMNDTLDEIFEDSGDEEESQDIVNQVLDEIGIEISGKMAH 180
>sp|Q5F3A2|CHM2B_CHICK Charged multivesicular body protein 2b (Chromatin modifying protein 2b) (CHMP2b) Length = 214 Score = 112 bits (279), Expect = 1e-24 Identities = 59/166 (35%), Positives = 97/166 (58%) Frame = +2 Query: 2 MKENQRALNKTIRELEREKSRLENEEKKVINDIKKMAKQGQMDAVKIMAKDLVRTRNYVK 181 +KE R L T R + R+++ LE +E+++ +IKKMAK G +A K++AK LV+ R Sbjct: 14 IKEQNRELRGTQRTITRDRAALEKQERQLELEIKKMAKTGNKEACKVLAKQLVQLRKQKN 73 Query: 182 KFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQKIMMEFERESN 361 + + + + ++S + + + S MA AM +TMQ +NK M+ + + M F++E+ Sbjct: 74 RTYAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTMQNFQKENM 133 Query: 362 IMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLS 499 MEM EEM+ DT+DD +V QVLDE+GIEI+ ++ Sbjct: 134 KMEMTEEMINDTLDDIFDASDEEEESQDIVNQVLDEIGIEISGKMA 179
>sp|Q9UQN3|CHM2B_HUMAN Charged multivesicular body protein 2b (Chromatin modifying protein 2b) (CHMP2b) (CHMP2.5) (Vacuolar protein sorting 2-2) (Vps2-2) (hVps2-2) sp|Q5RAV2|CHM2B_PONPY Charged multivesicular body protein 2b (Chromatin modifying protein 2b) (CHMP2b) Length = 213 Score = 111 bits (278), Expect = 2e-24 Identities = 61/175 (34%), Positives = 99/175 (56%) Frame = +2 Query: 2 MKENQRALNKTIRELEREKSRLENEEKKVINDIKKMAKQGQMDAVKIMAKDLVRTRNYVK 181 +KE R L T R + R+++ LE +EK++ +IKKMAK G +A K++AK LV R Sbjct: 14 IKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACKVLAKQLVHLRKQKT 73 Query: 182 KFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQKIMMEFERESN 361 + + + + ++S + + + S MA AM +TMQ +NK M+ + + M F++E+ Sbjct: 74 RTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTMQNFQKENM 133 Query: 362 IMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNIDPSKDSI 526 MEM EEM+ DT+DD +V QVLDE+GIEI+ ++ + S+ Sbjct: 134 KMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKAPSAARSL 188
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 70,022,475 Number of Sequences: 369166 Number of extensions: 1214449 Number of successful extensions: 4220 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3986 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4193 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 6921714800 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)