Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_013_E17
(752 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q7ZW25|CHM2A_BRARE Charged multivesicular body protein 2... 232 9e-61
sp|Q6DFS6|CHM2A_XENTR Charged multivesicular body protein 2... 231 2e-60
sp|Q6IP52|CHM2A_XENLA Charged multivesicular body protein 2... 230 3e-60
sp|Q9DB34|CHM2A_MOUSE Charged multivesicular body protein 2... 228 1e-59
sp|O43633|CHM2A_HUMAN Charged multivesicular body protein 2... 228 1e-59
sp|Q5ZHN1|CHM2A_CHICK Charged multivesicular body protein 2... 218 1e-56
sp|O14177|YDS1_SCHPO Hypothetical protein C4F8.01 in chromo... 141 2e-33
sp|Q6NXD2|CHM2B_BRARE Charged multivesicular body protein 2... 115 2e-25
sp|Q5F3A2|CHM2B_CHICK Charged multivesicular body protein 2... 112 1e-24
sp|Q9UQN3|CHM2B_HUMAN Charged multivesicular body protein 2... 111 2e-24
>sp|Q7ZW25|CHM2A_BRARE Charged multivesicular body protein 2a (Chromatin modifying protein
2a) (CHMP2a)
Length = 220
Score = 232 bits (591), Expect = 9e-61
Identities = 115/177 (64%), Positives = 144/177 (81%)
Frame = +2
Query: 2 MKENQRALNKTIRELEREKSRLENEEKKVINDIKKMAKQGQMDAVKIMAKDLVRTRNYVK 181
+++NQRALN+ +R+L+RE+ RLE +EKK+I DIKKMAKQGQMDAVKIMAKDLVRTR YVK
Sbjct: 15 LRQNQRALNRAMRDLDRERQRLEQQEKKIIADIKKMAKQGQMDAVKIMAKDLVRTRRYVK 74
Query: 182 KFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQKIMMEFERESN 361
KFI+M+ANIQAVSLKIQTL+S N+MAQAMKGVT+ M MN+ + LPQ+QKIMMEFER+S
Sbjct: 75 KFIMMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMATMNRQLKLPQIQKIMMEFERQSE 134
Query: 362 IMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNIDPSKDSIGI 532
IM+MKEEMM D IDDA+ +V QVLDELG+ ++D LSN+ + S+ +
Sbjct: 135 IMDMKEEMMNDAIDDAMGDEDDEEESDAVVSQVLDELGLTLSDELSNLPATGGSLSV 191
>sp|Q6DFS6|CHM2A_XENTR Charged multivesicular body protein 2a (Chromatin modifying protein
2a) (CHMP2a)
Length = 220
Score = 231 bits (588), Expect = 2e-60
Identities = 114/177 (64%), Positives = 143/177 (80%)
Frame = +2
Query: 2 MKENQRALNKTIRELEREKSRLENEEKKVINDIKKMAKQGQMDAVKIMAKDLVRTRNYVK 181
+++NQRALNK +RE++RE+ +LE +EKK+I DIKKMAKQGQMDAVKIMAKDLVRTR YVK
Sbjct: 15 LRQNQRALNKAMREMDRERQKLEQQEKKIIADIKKMAKQGQMDAVKIMAKDLVRTRRYVK 74
Query: 182 KFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQKIMMEFERESN 361
KFI+M+ANIQAVSLKIQTL+S N+MAQAMKGVT+ M MN+ + LPQ+QKIMMEFE++S
Sbjct: 75 KFIMMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMATMNRQLKLPQIQKIMMEFEKQSE 134
Query: 362 IMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNIDPSKDSIGI 532
IM+MKEEMM D IDDA+ +V QVLDELG+ + D LSN+ + S+ +
Sbjct: 135 IMDMKEEMMNDAIDDAMGDEDDEEESDAVVSQVLDELGLTLTDELSNLPSTGGSLSV 191
>sp|Q6IP52|CHM2A_XENLA Charged multivesicular body protein 2a (Chromatin modifying protein
2a) (CHMP2a)
Length = 220
Score = 230 bits (587), Expect = 3e-60
Identities = 114/177 (64%), Positives = 143/177 (80%)
Frame = +2
Query: 2 MKENQRALNKTIRELEREKSRLENEEKKVINDIKKMAKQGQMDAVKIMAKDLVRTRNYVK 181
+++NQRALN+ +REL+RE+ +LE +EKK+I DIKKMAKQGQMDAVKIMAKDLVRTR YVK
Sbjct: 15 LRQNQRALNRAMRELDRERQKLEQQEKKIIADIKKMAKQGQMDAVKIMAKDLVRTRRYVK 74
Query: 182 KFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQKIMMEFERESN 361
KFI+M+ANIQAVSLKIQTL+S N+MAQAMKGVT+ M MN+ + LPQ+QKIMMEFE++S
Sbjct: 75 KFIMMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMATMNRQLKLPQIQKIMMEFEKQSE 134
Query: 362 IMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNIDPSKDSIGI 532
IM+MKEEMM D IDDA+ +V QVLDELG+ + D LSN+ + S+ +
Sbjct: 135 IMDMKEEMMNDAIDDAMGDEDDEEESDAVVSQVLDELGLTLTDELSNLPSTGGSLSV 191
>sp|Q9DB34|CHM2A_MOUSE Charged multivesicular body protein 2a (Chromatin modifying protein
2a) (CHMP2a) (Vacuolar protein sorting 2) (mVps2)
Length = 222
Score = 228 bits (582), Expect = 1e-59
Identities = 112/177 (63%), Positives = 143/177 (80%)
Frame = +2
Query: 2 MKENQRALNKTIRELEREKSRLENEEKKVINDIKKMAKQGQMDAVKIMAKDLVRTRNYVK 181
+++NQRALN+ +REL+RE+ +LE +EKK+I DIKKMAKQGQMDAV+IMAKDLVRTR YV+
Sbjct: 15 LRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVR 74
Query: 182 KFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQKIMMEFERESN 361
KF+LM+ANIQAVSLKIQTL+S N+MAQAMKGVT+ M MN+ + LPQ+QKIMMEFER++
Sbjct: 75 KFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFERQAE 134
Query: 362 IMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNIDPSKDSIGI 532
IM+MKEEMM D IDDA+ +V QVLDELG+ + D LSN+ + S+ +
Sbjct: 135 IMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLPSTGGSLSV 191
>sp|O43633|CHM2A_HUMAN Charged multivesicular body protein 2a (Chromatin modifying protein
2a) (CHMP2a) (Vacuolar protein sorting 2-1) (Vps2-1)
(hVps2-1) (Putative breast adenocarcinoma marker BC-2)
Length = 222
Score = 228 bits (582), Expect = 1e-59
Identities = 112/177 (63%), Positives = 143/177 (80%)
Frame = +2
Query: 2 MKENQRALNKTIRELEREKSRLENEEKKVINDIKKMAKQGQMDAVKIMAKDLVRTRNYVK 181
+++NQRALN+ +REL+RE+ +LE +EKK+I DIKKMAKQGQMDAV+IMAKDLVRTR YV+
Sbjct: 15 LRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVR 74
Query: 182 KFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQKIMMEFERESN 361
KF+LM+ANIQAVSLKIQTL+S N+MAQAMKGVT+ M MN+ + LPQ+QKIMMEFER++
Sbjct: 75 KFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFERQAE 134
Query: 362 IMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNIDPSKDSIGI 532
IM+MKEEMM D IDDA+ +V QVLDELG+ + D LSN+ + S+ +
Sbjct: 135 IMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLPSTGGSLSV 191
>sp|Q5ZHN1|CHM2A_CHICK Charged multivesicular body protein 2a (Chromatin modifying protein
2a) (CHMP2a)
Length = 220
Score = 218 bits (556), Expect = 1e-56
Identities = 108/175 (61%), Positives = 138/175 (78%)
Frame = +2
Query: 2 MKENQRALNKTIRELEREKSRLENEEKKVINDIKKMAKQGQMDAVKIMAKDLVRTRNYVK 181
+++NQRAL + +REL+RE+ +LE +EKK+I DIKKMAKQGQMDAVKIMAKDLVRTR YVK
Sbjct: 15 LRQNQRALTRAMRELDRERQKLEAQEKKIIIDIKKMAKQGQMDAVKIMAKDLVRTRRYVK 74
Query: 182 KFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQKIMMEFERESN 361
KFI M+AN+QAVSLKIQTL+S N+MA AMKGVT+ M MN+ + LPQ+QKIMMEFE+++
Sbjct: 75 KFITMRANVQAVSLKIQTLKSNNSMALAMKGVTKAMATMNRQLKLPQIQKIMMEFEKQAG 134
Query: 362 IMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNIDPSKDSI 526
IM+MKEE+M D IDDA+ +V QVLDELG+ + D L+ + P S+
Sbjct: 135 IMDMKEELMNDAIDDAMGDEDDEEESDAVVSQVLDELGLNLTDELATLPPPGGSL 189
>sp|O14177|YDS1_SCHPO Hypothetical protein C4F8.01 in chromosome I
Length = 210
Score = 141 bits (356), Expect = 2e-33
Identities = 69/165 (41%), Positives = 113/165 (68%)
Frame = +2
Query: 2 MKENQRALNKTIRELEREKSRLENEEKKVINDIKKMAKQGQMDAVKIMAKDLVRTRNYVK 181
++ +QR+L + REL+RE+++L+ E+ +I +IK AK G A +I A+DL+R RN K
Sbjct: 18 LRAHQRSLGRAERELDRERTKLDQRERALIQEIKGSAKAGNTGAARIQARDLMRLRNSRK 77
Query: 182 KFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQKIMMEFERESN 361
K + K +QA+SL++QT+R++ M Q+M+G TR + MNKSMN+P + +I +FERE+
Sbjct: 78 KMMNAKTQLQAISLRLQTMRTSEQMMQSMRGATRLLTGMNKSMNIPAMARITQQFERENE 137
Query: 362 IMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTL 496
IME ++EM+ + +DDAL +LV +VLDE+G++++ L
Sbjct: 138 IMEQRQEMIDENMDDAL-EEDDEEEADELVNKVLDEIGVDLSQGL 181
>sp|Q6NXD2|CHM2B_BRARE Charged multivesicular body protein 2b (Chromatin modifying protein
2b) (CHMP2b)
Length = 214
Score = 115 bits (287), Expect = 2e-25
Identities = 59/167 (35%), Positives = 100/167 (59%)
Frame = +2
Query: 2 MKENQRALNKTIRELEREKSRLENEEKKVINDIKKMAKQGQMDAVKIMAKDLVRTRNYVK 181
+KE + L T R++ R+++ LE +EK++ +IKKMAK G DA K++AK LV+ R
Sbjct: 14 IKEQNKELRGTQRQIARDRTALEKQEKQLEMEIKKMAKTGNRDACKVLAKQLVQVRKQKT 73
Query: 182 KFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQKIMMEFERESN 361
+ + + + ++S + + + S MA AM T+TMQ +NK M+ + + + F++E+
Sbjct: 74 RTYAVSSKVTSMSTQTKLMNSQMKMAGAMATTTKTMQAVNKKMDPKKTMQTLQNFQKETA 133
Query: 362 IMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSN 502
M+M EEMM DT+D+ +V QVLDE+GIEI+ +++
Sbjct: 134 KMDMTEEMMNDTLDEIFEDSGDEEESQDIVNQVLDEIGIEISGKMAH 180
>sp|Q5F3A2|CHM2B_CHICK Charged multivesicular body protein 2b (Chromatin modifying protein
2b) (CHMP2b)
Length = 214
Score = 112 bits (279), Expect = 1e-24
Identities = 59/166 (35%), Positives = 97/166 (58%)
Frame = +2
Query: 2 MKENQRALNKTIRELEREKSRLENEEKKVINDIKKMAKQGQMDAVKIMAKDLVRTRNYVK 181
+KE R L T R + R+++ LE +E+++ +IKKMAK G +A K++AK LV+ R
Sbjct: 14 IKEQNRELRGTQRTITRDRAALEKQERQLELEIKKMAKTGNKEACKVLAKQLVQLRKQKN 73
Query: 182 KFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQKIMMEFERESN 361
+ + + + ++S + + + S MA AM +TMQ +NK M+ + + M F++E+
Sbjct: 74 RTYAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTMQNFQKENM 133
Query: 362 IMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLS 499
MEM EEM+ DT+DD +V QVLDE+GIEI+ ++
Sbjct: 134 KMEMTEEMINDTLDDIFDASDEEEESQDIVNQVLDEIGIEISGKMA 179
>sp|Q9UQN3|CHM2B_HUMAN Charged multivesicular body protein 2b (Chromatin modifying protein
2b) (CHMP2b) (CHMP2.5) (Vacuolar protein sorting 2-2)
(Vps2-2) (hVps2-2)
sp|Q5RAV2|CHM2B_PONPY Charged multivesicular body protein 2b (Chromatin modifying protein
2b) (CHMP2b)
Length = 213
Score = 111 bits (278), Expect = 2e-24
Identities = 61/175 (34%), Positives = 99/175 (56%)
Frame = +2
Query: 2 MKENQRALNKTIRELEREKSRLENEEKKVINDIKKMAKQGQMDAVKIMAKDLVRTRNYVK 181
+KE R L T R + R+++ LE +EK++ +IKKMAK G +A K++AK LV R
Sbjct: 14 IKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACKVLAKQLVHLRKQKT 73
Query: 182 KFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQKIMMEFERESN 361
+ + + + ++S + + + S MA AM +TMQ +NK M+ + + M F++E+
Sbjct: 74 RTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTMQNFQKENM 133
Query: 362 IMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNIDPSKDSI 526
MEM EEM+ DT+DD +V QVLDE+GIEI+ ++ + S+
Sbjct: 134 KMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKAPSAARSL 188
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,730,225
Number of Sequences: 369166
Number of extensions: 1210880
Number of successful extensions: 4234
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4001
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4207
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6873311200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)