Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_M13
(609 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q7ZW25|CHM2A_BRARE Charged multivesicular body protein 2... 160 3e-39
sp|Q6IP52|CHM2A_XENLA Charged multivesicular body protein 2... 158 9e-39
sp|Q6DFS6|CHM2A_XENTR Charged multivesicular body protein 2... 158 9e-39
sp|Q9DB34|CHM2A_MOUSE Charged multivesicular body protein 2... 157 2e-38
sp|O43633|CHM2A_HUMAN Charged multivesicular body protein 2... 157 2e-38
sp|Q5ZHN1|CHM2A_CHICK Charged multivesicular body protein 2... 150 3e-36
sp|O14177|YDS1_SCHPO Hypothetical protein C4F8.01 in chromo... 103 4e-22
sp|P36108|DID4_YEAST DOA4-independent degradation protein 4... 85 1e-16
sp|Q8BJF9|CHM2B_MOUSE Charged multivesicular body protein 2... 74 4e-13
sp|Q9UQN3|CHM2B_HUMAN Charged multivesicular body protein 2... 74 4e-13
>sp|Q7ZW25|CHM2A_BRARE Charged multivesicular body protein 2a (Chromatin modifying protein
2a) (CHMP2a)
Length = 220
Score = 160 bits (404), Expect = 3e-39
Identities = 80/128 (62%), Positives = 99/128 (77%)
Frame = +2
Query: 2 KDLVRTRNYVKKFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQ 181
KDLVRTR YVKKFI+M+ANIQAVSLKIQTL+S N+MAQAMKGVT+ M MN+ + LPQ+Q
Sbjct: 64 KDLVRTRRYVKKFIMMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMATMNRQLKLPQIQ 123
Query: 182 KIMMEFERESNIMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNID 361
KIMMEFER+S IM+MKEEMM D IDDA+ +V QVLDELG+ ++D LSN+
Sbjct: 124 KIMMEFERQSEIMDMKEEMMNDAIDDAMGDEDDEEESDAVVSQVLDELGLTLSDELSNLP 183
Query: 362 PSKDSIGI 385
+ S+ +
Sbjct: 184 ATGGSLSV 191
>sp|Q6IP52|CHM2A_XENLA Charged multivesicular body protein 2a (Chromatin modifying protein
2a) (CHMP2a)
Length = 220
Score = 158 bits (400), Expect = 9e-39
Identities = 79/128 (61%), Positives = 98/128 (76%)
Frame = +2
Query: 2 KDLVRTRNYVKKFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQ 181
KDLVRTR YVKKFI+M+ANIQAVSLKIQTL+S N+MAQAMKGVT+ M MN+ + LPQ+Q
Sbjct: 64 KDLVRTRRYVKKFIMMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMATMNRQLKLPQIQ 123
Query: 182 KIMMEFERESNIMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNID 361
KIMMEFE++S IM+MKEEMM D IDDA+ +V QVLDELG+ + D LSN+
Sbjct: 124 KIMMEFEKQSEIMDMKEEMMNDAIDDAMGDEDDEEESDAVVSQVLDELGLTLTDELSNLP 183
Query: 362 PSKDSIGI 385
+ S+ +
Sbjct: 184 STGGSLSV 191
>sp|Q6DFS6|CHM2A_XENTR Charged multivesicular body protein 2a (Chromatin modifying protein
2a) (CHMP2a)
Length = 220
Score = 158 bits (400), Expect = 9e-39
Identities = 79/128 (61%), Positives = 98/128 (76%)
Frame = +2
Query: 2 KDLVRTRNYVKKFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQ 181
KDLVRTR YVKKFI+M+ANIQAVSLKIQTL+S N+MAQAMKGVT+ M MN+ + LPQ+Q
Sbjct: 64 KDLVRTRRYVKKFIMMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMATMNRQLKLPQIQ 123
Query: 182 KIMMEFERESNIMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNID 361
KIMMEFE++S IM+MKEEMM D IDDA+ +V QVLDELG+ + D LSN+
Sbjct: 124 KIMMEFEKQSEIMDMKEEMMNDAIDDAMGDEDDEEESDAVVSQVLDELGLTLTDELSNLP 183
Query: 362 PSKDSIGI 385
+ S+ +
Sbjct: 184 STGGSLSV 191
>sp|Q9DB34|CHM2A_MOUSE Charged multivesicular body protein 2a (Chromatin modifying protein
2a) (CHMP2a) (Vacuolar protein sorting 2) (mVps2)
Length = 222
Score = 157 bits (398), Expect = 2e-38
Identities = 78/128 (60%), Positives = 98/128 (76%)
Frame = +2
Query: 2 KDLVRTRNYVKKFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQ 181
KDLVRTR YV+KF+LM+ANIQAVSLKIQTL+S N+MAQAMKGVT+ M MN+ + LPQ+Q
Sbjct: 64 KDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQ 123
Query: 182 KIMMEFERESNIMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNID 361
KIMMEFER++ IM+MKEEMM D IDDA+ +V QVLDELG+ + D LSN+
Sbjct: 124 KIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLP 183
Query: 362 PSKDSIGI 385
+ S+ +
Sbjct: 184 STGGSLSV 191
>sp|O43633|CHM2A_HUMAN Charged multivesicular body protein 2a (Chromatin modifying protein
2a) (CHMP2a) (Vacuolar protein sorting 2-1) (Vps2-1)
(hVps2-1) (Putative breast adenocarcinoma marker BC-2)
Length = 222
Score = 157 bits (398), Expect = 2e-38
Identities = 78/128 (60%), Positives = 98/128 (76%)
Frame = +2
Query: 2 KDLVRTRNYVKKFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQ 181
KDLVRTR YV+KF+LM+ANIQAVSLKIQTL+S N+MAQAMKGVT+ M MN+ + LPQ+Q
Sbjct: 64 KDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQ 123
Query: 182 KIMMEFERESNIMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNID 361
KIMMEFER++ IM+MKEEMM D IDDA+ +V QVLDELG+ + D LSN+
Sbjct: 124 KIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLP 183
Query: 362 PSKDSIGI 385
+ S+ +
Sbjct: 184 STGGSLSV 191
>sp|Q5ZHN1|CHM2A_CHICK Charged multivesicular body protein 2a (Chromatin modifying protein
2a) (CHMP2a)
Length = 220
Score = 150 bits (378), Expect = 3e-36
Identities = 74/126 (58%), Positives = 94/126 (74%)
Frame = +2
Query: 2 KDLVRTRNYVKKFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQ 181
KDLVRTR YVKKFI M+AN+QAVSLKIQTL+S N+MA AMKGVT+ M MN+ + LPQ+Q
Sbjct: 64 KDLVRTRRYVKKFITMRANVQAVSLKIQTLKSNNSMALAMKGVTKAMATMNRQLKLPQIQ 123
Query: 182 KIMMEFERESNIMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNID 361
KIMMEFE+++ IM+MKEE+M D IDDA+ +V QVLDELG+ + D L+ +
Sbjct: 124 KIMMEFEKQAGIMDMKEELMNDAIDDAMGDEDDEEESDAVVSQVLDELGLNLTDELATLP 183
Query: 362 PSKDSI 379
P S+
Sbjct: 184 PPGGSL 189
>sp|O14177|YDS1_SCHPO Hypothetical protein C4F8.01 in chromosome I
Length = 210
Score = 103 bits (256), Expect = 4e-22
Identities = 50/116 (43%), Positives = 80/116 (68%)
Frame = +2
Query: 2 KDLVRTRNYVKKFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQ 181
+DL+R RN KK + K +QA+SL++QT+R++ M Q+M+G TR + MNKSMN+P +
Sbjct: 67 RDLMRLRNSRKKMMNAKTQLQAISLRLQTMRTSEQMMQSMRGATRLLTGMNKSMNIPAMA 126
Query: 182 KIMMEFERESNIMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTL 349
+I +FERE+ IME ++EM+ + +DDAL +LV +VLDE+G++++ L
Sbjct: 127 RITQQFERENEIMEQRQEMIDENMDDAL-EEDDEEEADELVNKVLDEIGVDLSQGL 181
>sp|P36108|DID4_YEAST DOA4-independent degradation protein 4 (Vacuolar protein
sorting-associated protein VPS2)
Length = 151
Score = 85.1 bits (209), Expect = 1e-16
Identities = 41/104 (39%), Positives = 70/104 (67%), Gaps = 1/104 (0%)
Frame = +2
Query: 47 MKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQKIMMEFERESNIMEM 226
MKA +QA+SL+IQ +RS++ M ++M T + MN++MNLPQLQ+I MEFE++S++M
Sbjct: 1 MKAQLQAISLRIQAVRSSDQMTRSMSEATGLLAGMNRTMNLPQLQRISMEFEKQSDLMGQ 60
Query: 227 KEEMMTDTIDDAL-XXXXXXXXXXKLVQQVLDELGIEIADTLSN 355
++E M + ID+ + ++V +VLDE+G+++ L +
Sbjct: 61 RQEFMDEAIDNVMGDEVDEDEEADEIVNKVLDEIGVDLNSQLQS 104
>sp|Q8BJF9|CHM2B_MOUSE Charged multivesicular body protein 2b (Chromatin modifying protein
2b) (CHMP2b)
Length = 213
Score = 73.6 bits (179), Expect = 4e-13
Identities = 40/126 (31%), Positives = 66/126 (52%)
Frame = +2
Query: 2 KDLVRTRNYVKKFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQ 181
K LV R + + + + ++S + + + S MA AM +TMQ +NK M+ +
Sbjct: 63 KQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTL 122
Query: 182 KIMMEFERESNIMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNID 361
+ M F++E+ MEM EEM+ DT+DD +V QVLDE+GIEI+ ++
Sbjct: 123 QTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKAP 182
Query: 362 PSKDSI 379
+ S+
Sbjct: 183 SAARSL 188
>sp|Q9UQN3|CHM2B_HUMAN Charged multivesicular body protein 2b (Chromatin modifying protein
2b) (CHMP2b) (CHMP2.5) (Vacuolar protein sorting 2-2)
(Vps2-2) (hVps2-2)
sp|Q5RAV2|CHM2B_PONPY Charged multivesicular body protein 2b (Chromatin modifying protein
2b) (CHMP2b)
Length = 213
Score = 73.6 bits (179), Expect = 4e-13
Identities = 40/126 (31%), Positives = 66/126 (52%)
Frame = +2
Query: 2 KDLVRTRNYVKKFILMKANIQAVSLKIQTLRSTNAMAQAMKGVTRTMQRMNKSMNLPQLQ 181
K LV R + + + + ++S + + + S MA AM +TMQ +NK M+ +
Sbjct: 63 KQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTL 122
Query: 182 KIMMEFERESNIMEMKEEMMTDTIDDALXXXXXXXXXXKLVQQVLDELGIEIADTLSNID 361
+ M F++E+ MEM EEM+ DT+DD +V QVLDE+GIEI+ ++
Sbjct: 123 QTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKAP 182
Query: 362 PSKDSI 379
+ S+
Sbjct: 183 SAARSL 188
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,240,220
Number of Sequences: 369166
Number of extensions: 1003573
Number of successful extensions: 2775
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2687
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2763
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4748907085
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)