Planaria EST Database


DrC_00476

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00476
         (1313 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P57780|ACTN4_MOUSE  Alpha-actinin 4 (Non-muscle alpha-act...   361   2e-99
sp|O43707|ACTN4_HUMAN  Alpha-actinin 4 (Non-muscle alpha-act...   360   5e-99
sp|Q9QXQ0|ACTN4_RAT  Alpha-actinin 4 (Non-muscle alpha-actin...   358   2e-98
sp|Q9Z1P2|ACTN1_RAT  Alpha-actinin 1 (Alpha-actinin cytoskel...   354   3e-97
sp|P12814|ACTN1_HUMAN  Alpha-actinin 1 (Alpha-actinin cytosk...   353   8e-97
sp|P05094|ACTN1_CHICK  Alpha-actinin 1 (Alpha-actinin cytosk...   353   8e-97
sp|Q7TPR4|ACTN1_MOUSE  Alpha-actinin 1 (Alpha-actinin cytosk...   352   1e-96
sp|Q90734|ACTN4_CHICK  Alpha-actinin 4 (Non-muscle alpha-act...   351   2e-96
sp|P18091|ACTN_DROME  Alpha-actinin, sarcomeric (F-actin cro...   344   4e-94
sp|Q08043|ACTN3_HUMAN  Alpha-actinin 3 (Alpha actinin skelet...   342   1e-93
>sp|P57780|ACTN4_MOUSE Alpha-actinin 4 (Non-muscle alpha-actinin 4) (F-actin cross linking
            protein)
          Length = 912

 Score =  361 bits (927), Expect = 2e-99
 Identities = 187/390 (47%), Positives = 265/390 (67%), Gaps = 3/390 (0%)
 Frame = +3

Query: 6    LEEIDQMQLDYAKKIAPFYNWIEQAKEDLQDSHILLYIDEVKILIEKQDEFKKSMENAKL 185
            LE IDQ+ L+YAK+ APF NW+E A EDLQD  I+  I+E++ LI   D+FK ++ +A  
Sbjct: 524  LETIDQLHLEYAKRAAPFNNWMESAMEDLQDMFIVHTIEEIEGLISAHDQFKSTLPDADR 583

Query: 186  EYNMLNQVDSQIKNRALENNLNQISENPYTLLSQTALSVE*NKLSDLLPLRDEFLQKELS 365
            E   +  +  + +  A  N++     NPYT ++   ++ +  K+  L+P RD  L +E S
Sbjct: 584  EREAILAIHKEAQRIAESNHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEEQS 643

Query: 366  QQTKNEKLRENFGSLANKLGPWIDEKQQFINYLSSGENVSTLESQKSQIEHLETEINEYR 545
            +Q  NE LR  F S AN +GPWI  K + I  +S   N  TLE Q S ++  E  I +Y+
Sbjct: 644  KQQSNEHLRRQFASQANMVGPWIQTKMEEIGRISIEMN-GTLEDQLSHLKQYERSIVDYK 702

Query: 546  KLAMEVDKCSQELQQNMIFETPNCRYSMETLRVSWEQLQSSMRRSKSEIEDQILTRDSKG 725
                 +++  Q +Q+ +IF+  +  Y+ME +RV WEQL +++ R+ +E+E+QILTRD+KG
Sbjct: 703  PSLDLLEQQHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKG 762

Query: 726  ISQSQMDEFRRCFNHFDKNKTRTLEPKEFKACLVSLGCNLKEEK-GEADFAKIMSEVDPN 902
            ISQ QM EFR  FNHFDK+    L P+EFKACL+SLG +++ ++ G+A+F +IMS VDPN
Sbjct: 763  ISQEQMQEFRASFNHFDKDHGGALGPEEFKACLISLGYDVENDRQGDAEFNRIMSVVDPN 822

Query: 903  RSGVVTFGAFIDYMAKETTEQDTLEQILQSFKVLCQDRDYITAEELRRELPSAEAEYCIA 1082
             SG+VTF AFID+M++ETT+ DT +Q++ SFKVL  D+++ITAEELRRELP  +AEYCIA
Sbjct: 823  HSGLVTFQAFIDFMSRETTDTDTADQVIASFKVLAGDKNFITAEELRRELPPDQAEYCIA 882

Query: 1083 NMAPY--PDGGEGALDYKLFASSLYGHSDL 1166
             MAPY  PD   GALDYK F+++LYG SDL
Sbjct: 883  RMAPYQGPDAAPGALDYKSFSTALYGESDL 912

 Score = 39.7 bits (91), Expect = 0.020
 Identities = 48/246 (19%), Positives = 103/246 (41%), Gaps = 10/246 (4%)
 Frame = +3

Query: 9    EEIDQMQLDYAKKIAPFYNWIEQAKEDLQDSHILLYIDEVKILIEKQDEFKKSMENAKLE 188
            +E + +  DY +  +    WI +    L+D      I E++  +E   ++++  +  K++
Sbjct: 290  QENEHLMEDYERLASDLLEWIRRTIPWLEDRVPQKTIQEMQQKLEDFRDYRRVHKPPKVQ 349

Query: 189  YNMLNQVDSQIKNRALENNLNQISENPYTLLSQTALSVE*NK----LSDLLPLRDEFLQK 356
                 +   +I    L+  L ++S  P  + S+  +  + N     L       +E+L  
Sbjct: 350  ----EKCQLEINFNTLQTKL-RLSNRPAFMPSEGRMVSDINNGWQHLEQAEKGYEEWLLN 404

Query: 357  ELSQQTKNEKLRENFGSLANKLGPWIDEKQQFINYLSSGENVSTLESQKSQI---EHLET 527
            E+ +  + + L E F   A+    W D K+  +         +TL   K+ I   E  E+
Sbjct: 405  EIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLK--QRDYETATLSDIKALIRKHEAFES 462

Query: 528  EINEYRKLAMEVDKCSQELQQNMIFETPNCRYSMETLRVSWEQLQS---SMRRSKSEIED 698
            ++  ++    ++   +QEL +   +++ N     + +   W+ L S   S R +  + E 
Sbjct: 463  DLAAHQDRVEQIAAIAQELNELDYYDSHNVNTRCQKICDQWDNLGSLTHSRREALEKTEK 522

Query: 699  QILTRD 716
            Q+ T D
Sbjct: 523  QLETID 528
>sp|O43707|ACTN4_HUMAN Alpha-actinin 4 (Non-muscle alpha-actinin 4) (F-actin cross linking
            protein)
          Length = 911

 Score =  360 bits (924), Expect = 5e-99
 Identities = 188/390 (48%), Positives = 265/390 (67%), Gaps = 3/390 (0%)
 Frame = +3

Query: 6    LEEIDQMQLDYAKKIAPFYNWIEQAKEDLQDSHILLYIDEVKILIEKQDEFKKSMENAKL 185
            LE IDQ+ L+YAK+ APF NW+E A EDLQD  I+  I+E++ LI   D+FK ++ +A  
Sbjct: 523  LEAIDQLHLEYAKRAAPFNNWMESAMEDLQDMFIVHTIEEIEGLISAHDQFKSTLPDADR 582

Query: 186  EYNMLNQVDSQIKNRALENNLNQISENPYTLLSQTALSVE*NKLSDLLPLRDEFLQKELS 365
            E   +  +  + +  A  N++     NPYT ++   ++ +  K+  L+P RD  L +E S
Sbjct: 583  EREAILAIHKEAQRIAESNHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEEQS 642

Query: 366  QQTKNEKLRENFGSLANKLGPWIDEKQQFINYLSSGENVSTLESQKSQIEHLETEINEYR 545
            +Q  NE LR  F S AN +GPWI  K + I  +S   N  TLE Q S ++  E  I +Y+
Sbjct: 643  KQQSNEHLRRQFASQANVVGPWIQTKMEEIGRISIEMN-GTLEDQLSHLKQYERSIVDYK 701

Query: 546  KLAMEVDKCSQELQQNMIFETPNCRYSMETLRVSWEQLQSSMRRSKSEIEDQILTRDSKG 725
                 +++  Q +Q+ +IF+  +  Y+ME +RV WEQL +++ R+ +E+E+QILTRD+KG
Sbjct: 702  PNLDLLEQQHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKG 761

Query: 726  ISQSQMDEFRRCFNHFDKNKTRTLEPKEFKACLVSLGCNLKEEK-GEADFAKIMSEVDPN 902
            ISQ QM EFR  FNHFDK+    L P+EFKACL+SLG +++ ++ GEA+F +IMS VDPN
Sbjct: 762  ISQEQMQEFRASFNHFDKDHGGALGPEEFKACLISLGYDVENDRQGEAEFNRIMSLVDPN 821

Query: 903  RSGVVTFGAFIDYMAKETTEQDTLEQILQSFKVLCQDRDYITAEELRRELPSAEAEYCIA 1082
             SG+VTF AFID+M++ETT+ DT +Q++ SFKVL  D+++ITAEELRRELP  +AEYCIA
Sbjct: 822  HSGLVTFQAFIDFMSRETTDTDTADQVIASFKVLAGDKNFITAEELRRELPPDQAEYCIA 881

Query: 1083 NMAPY--PDGGEGALDYKLFASSLYGHSDL 1166
             MAPY  PD   GALDYK F+++LYG SDL
Sbjct: 882  RMAPYQGPDAVPGALDYKSFSTALYGESDL 911

 Score = 40.0 bits (92), Expect = 0.015
 Identities = 53/276 (19%), Positives = 117/276 (42%), Gaps = 12/276 (4%)
 Frame = +3

Query: 9    EEIDQMQLDYAKKIAPFYNWIEQAKEDLQDSHILLYIDEVKILIEKQDEFKKSMENAKLE 188
            +E + +  DY K  +    WI +    L+D      I E++  +E   ++++  +  K++
Sbjct: 289  QENEHLMEDYEKLASDLLEWIRRTIPWLEDRVPQKTIQEMQQKLEDFRDYRRVHKPPKVQ 348

Query: 189  YNMLNQVDSQIKNRALENNLNQISENPYTLLSQTALSVE*NK----LSDLLPLRDEFLQK 356
                 +   +I    L+  L ++S  P  + S+  +  + N     L       +E+L  
Sbjct: 349  ----EKCQLEINFNTLQTKL-RLSNRPAFMPSEGKMVSDINNGWQHLEQAEKGYEEWLLN 403

Query: 357  ELSQQTKNEKLRENFGSLANKLGPWIDEKQQFINYLSSGENVSTLESQKSQI---EHLET 527
            E+ +  + + L E F   A+    W D K+  + +       +TL   K+ I   E  E+
Sbjct: 404  EIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLKH--RDYETATLSDIKALIRKHEAFES 461

Query: 528  EINEYRKLAMEVDKCSQELQQNMIFETPNCRYSMETLRVSWEQLQS---SMRRSKSEIED 698
            ++  ++    ++   +QEL +   +++ N     + +   W+ L S   S R +  + E 
Sbjct: 462  DLAAHQDRVEQIAAIAQELNELDYYDSHNVNTRCQKICDQWDALGSLTHSRREALEKTEK 521

Query: 699  QILTRDSKGISQSQMDEFRRC--FNHFDKNKTRTLE 800
            Q+     + I Q  ++  +R   FN++ ++    L+
Sbjct: 522  QL-----EAIDQLHLEYAKRAAPFNNWMESAMEDLQ 552
>sp|Q9QXQ0|ACTN4_RAT Alpha-actinin 4 (Non-muscle alpha-actinin 4) (F-actin cross linking
            protein)
          Length = 911

 Score =  358 bits (918), Expect = 2e-98
 Identities = 186/390 (47%), Positives = 263/390 (67%), Gaps = 3/390 (0%)
 Frame = +3

Query: 6    LEEIDQMQLDYAKKIAPFYNWIEQAKEDLQDSHILLYIDEVKILIEKQDEFKKSMENAKL 185
            LE IDQ+ L+YAK+ APF NW+E A EDLQD  I+  I+E++ LI   D+FK ++ +A  
Sbjct: 523  LETIDQLHLEYAKRAAPFNNWMESAMEDLQDMFIVHTIEEIEGLISAHDQFKSTLPDADR 582

Query: 186  EYNMLNQVDSQIKNRALENNLNQISENPYTLLSQTALSVE*NKLSDLLPLRDEFLQKELS 365
            E   +  +  + +  A  N++     NPYT ++   ++ +  K+  L+P RD  L +E S
Sbjct: 583  EREAILAIHKEAQRIAESNHIKLSGSNPYTSVTPQIINSKWEKVQQLVPKRDHALLEEQS 642

Query: 366  QQTKNEKLRENFGSLANKLGPWIDEKQQFINYLSSGENVSTLESQKSQIEHLETEINEYR 545
            +Q  NE LR  F S AN +GPWI  K + I  +S   N  TLE Q S ++  E  I +Y+
Sbjct: 643  KQQSNEHLRRQFASQANMVGPWIQTKMEEIGRISIEMN-GTLEDQLSHLKQYERSIVDYK 701

Query: 546  KLAMEVDKCSQELQQNMIFETPNCRYSMETLRVSWEQLQSSMRRSKSEIEDQILTRDSKG 725
                 +++  Q +Q+ +IF+  +  Y+ME LRV WEQL +++ R+ +E+E+QILTRD+KG
Sbjct: 702  PNLDLLEQQHQLIQEALIFDNKHTNYTMEHLRVGWEQLLTTIARTINEVENQILTRDAKG 761

Query: 726  ISQSQMDEFRRCFNHFDKNKTRTLEPKEFKACLVSLGCNLKEEK-GEADFAKIMSEVDPN 902
            ISQ QM EFR  FNHFDK+    L P+EFK CL+SLG +++ ++ G+A+F +IMS VDPN
Sbjct: 762  ISQEQMQEFRASFNHFDKDHGGALGPEEFKGCLISLGYDVENDRQGDAEFNRIMSVVDPN 821

Query: 903  RSGVVTFGAFIDYMAKETTEQDTLEQILQSFKVLCQDRDYITAEELRRELPSAEAEYCIA 1082
             SG+VTF AFID+M+KETT+ DT +Q++ SFKVL  D+++IT EELR+ELP  +AEYCIA
Sbjct: 822  HSGLVTFQAFIDFMSKETTDTDTADQVIGSFKVLAGDKNFITVEELRKELPPDQAEYCIA 881

Query: 1083 NMAPY--PDGGEGALDYKLFASSLYGHSDL 1166
             MAPY  PD   GALDYK F+++LYG SDL
Sbjct: 882  RMAPYQGPDAAPGALDYKSFSTALYGESDL 911

 Score = 40.4 bits (93), Expect = 0.011
 Identities = 48/246 (19%), Positives = 104/246 (42%), Gaps = 10/246 (4%)
 Frame = +3

Query: 9    EEIDQMQLDYAKKIAPFYNWIEQAKEDLQDSHILLYIDEVKILIEKQDEFKKSMENAKLE 188
            +E + +  DY +  +    WI +    L+D      I E++  +E   ++++  +  K++
Sbjct: 289  QENEHLMEDYERLASDLLEWIRRTIPWLEDRVPQKTIQEMQQKLEDFRDYRRVHKPPKVQ 348

Query: 189  YNMLNQVDSQIKNRALENNLNQISENPYTLLSQTALSVE*NK----LSDLLPLRDEFLQK 356
                 +   +I    L+  L ++S  P  + S+  +  + N     L       +E+L  
Sbjct: 349  ----EKCQLEINFNTLQTKL-RLSNRPAFMPSEGRMVSDINNGWQHLEQAEKGYEEWLLN 403

Query: 357  ELSQQTKNEKLRENFGSLANKLGPWIDEKQQFINYLSSGENVSTLESQKSQI---EHLET 527
            E+ +  + + L E F   A+    W D K+  + +       +TL   K+ I   E  E+
Sbjct: 404  EIPRLERLDHLAEKFRQKASIHEAWTDGKEAMLKHRDY--ETATLSDIKALIRKHEAFES 461

Query: 528  EINEYRKLAMEVDKCSQELQQNMIFETPNCRYSMETLRVSWEQLQS---SMRRSKSEIED 698
            ++  ++    ++   +QEL +   +++ N     + +   W+ L S   S R +  + E 
Sbjct: 462  DLAAHQDRVEQIAAIAQELNELDYYDSHNVNTRCQKICDQWDNLGSLTHSRREALEKTEK 521

Query: 699  QILTRD 716
            Q+ T D
Sbjct: 522  QLETID 527
>sp|Q9Z1P2|ACTN1_RAT Alpha-actinin 1 (Alpha-actinin cytoskeletal isoform) (Non-muscle
            alpha-actinin 1) (F-actin cross linking protein)
          Length = 892

 Score =  354 bits (909), Expect = 3e-97
 Identities = 183/391 (46%), Positives = 268/391 (68%), Gaps = 3/391 (0%)
 Frame = +3

Query: 3    LLEEIDQMQLDYAKKIAPFYNWIEQAKEDLQDSHILLYIDEVKILIEKQDEFKKSMENAK 182
            LLE IDQ+ L+YAK+ APF NW+E A EDLQD+ I+  I+E++ L    ++FK ++ +A 
Sbjct: 503  LLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDAD 562

Query: 183  LEYNMLNQVDSQIKNRALENNLNQISENPYTLLSQTALSVE*NKLSDLLPLRDEFLQKEL 362
             E   +  + +++       ++N    NPYT ++   ++ + + +  L+P RD+ L +E 
Sbjct: 563  KERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEH 622

Query: 363  SQQTKNEKLRENFGSLANKLGPWIDEKQQFINYLSSGENVSTLESQKSQIEHLETEINEY 542
            S+Q  NE+LR+ FG+ AN +GPWI  K + I  +S  E   TLE Q S +   E  I  Y
Sbjct: 623  SRQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISI-EMHGTLEDQLSHLRQYEKSIVNY 681

Query: 543  RKLAMEVDKCSQELQQNMIFETPNCRYSMETLRVSWEQLQSSMRRSKSEIEDQILTRDSK 722
            +    +++   Q +Q+ +IF+  +  Y+ME +RV WEQL +++ R+ +E+E+QILTRD+K
Sbjct: 682  KPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAK 741

Query: 723  GISQSQMDEFRRCFNHFDKNKTRTLEPKEFKACLVSLGCNL-KEEKGEADFAKIMSEVDP 899
            GISQ QM+EFR  FNHFD++ + TL P+EFKACL+SLG ++  + +GEA+FA+IMS VDP
Sbjct: 742  GISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDP 801

Query: 900  NRSGVVTFGAFIDYMAKETTEQDTLEQILQSFKVLCQDRDYITAEELRRELPSAEAEYCI 1079
            NR GVVTF AFID+M++ET + DT +Q++ SFK+L  D++YIT +ELRRELP  +AEYCI
Sbjct: 802  NRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITGDELRRELPPDQAEYCI 861

Query: 1080 ANMAPY--PDGGEGALDYKLFASSLYGHSDL 1166
            A MAPY  PD   GALDY  F+++LYG SDL
Sbjct: 862  ARMAPYAGPDSVPGALDYMSFSTALYGESDL 892

 Score = 38.1 bits (87), Expect = 0.057
 Identities = 41/240 (17%), Positives = 102/240 (42%), Gaps = 11/240 (4%)
 Frame = +3

Query: 9   EEIDQMQLDYAKKIAPFYNWIEQAKEDLQDSHILLYIDEVKILIEKQDEFKKSMENAKLE 188
           +E +Q+  DY K  +    WI +    L++    +  + ++ + +K ++F+        +
Sbjct: 270 QENEQLMEDYEKLASDLLEWIRRTIPWLENR---VPENTMQAMQQKLEDFR--------D 318

Query: 189 YNMLNQVDSQIKNRALENNLN------QISENPYTLLSQTALSVE*NKLSDLLPLRD--- 341
           Y  L++     +   LE N N      ++S  P  + S+  +  + N     L   +   
Sbjct: 319 YRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNAWGCLEQAEKGY 378

Query: 342 -EFLQKELSQQTKNEKLRENFGSLANKLGPWIDEKQQFINYLS-SGENVSTLESQKSQIE 515
            E+L  E+ +  + + L E F   A+    W D K+  +         +S +++   + E
Sbjct: 379 EEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHE 438

Query: 516 HLETEINEYRKLAMEVDKCSQELQQNMIFETPNCRYSMETLRVSWEQLQSSMRRSKSEIE 695
             E+++  ++    ++   +QEL +   +++P+     + +   W+ L +  ++ +  +E
Sbjct: 439 AFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALE 498

 Score = 31.2 bits (69), Expect = 6.9
 Identities = 22/85 (25%), Positives = 45/85 (52%), Gaps = 3/85 (3%)
 Frame = +3

Query: 354 KELSQQTKNEKLRENFGSLANKLGPWIDEKQQFINYLSSGENVSTLESQKSQIEHLETEI 533
           K L+   +NE+L E++  LA+ L  WI   ++ I +L +    +T+++ + ++E    + 
Sbjct: 264 KVLAVNQENEQLMEDYEKLASDLLEWI---RRTIPWLENRVPENTMQAMQQKLE----DF 316

Query: 534 NEYRKL---AMEVDKCSQELQQNMI 599
            +YR+L       +KC  E+  N +
Sbjct: 317 RDYRRLHKPPKVQEKCQLEINFNTL 341
>sp|P12814|ACTN1_HUMAN Alpha-actinin 1 (Alpha-actinin cytoskeletal isoform) (Non-muscle
            alpha-actinin 1) (F-actin cross linking protein)
          Length = 892

 Score =  353 bits (905), Expect = 8e-97
 Identities = 182/391 (46%), Positives = 268/391 (68%), Gaps = 3/391 (0%)
 Frame = +3

Query: 3    LLEEIDQMQLDYAKKIAPFYNWIEQAKEDLQDSHILLYIDEVKILIEKQDEFKKSMENAK 182
            LLE IDQ+ L+YAK+ APF NW+E A EDLQD+ I+  I+E++ L    ++FK ++ +A 
Sbjct: 503  LLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDAD 562

Query: 183  LEYNMLNQVDSQIKNRALENNLNQISENPYTLLSQTALSVE*NKLSDLLPLRDEFLQKEL 362
             E   +  + +++       ++N    NPYT ++   ++ + + +  L+P RD+ L +E 
Sbjct: 563  KERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEH 622

Query: 363  SQQTKNEKLRENFGSLANKLGPWIDEKQQFINYLSSGENVSTLESQKSQIEHLETEINEY 542
            ++Q  NE+LR+ FG+ AN +GPWI  K + I  +S  E   TLE Q S +   E  I  Y
Sbjct: 623  ARQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISI-EMHGTLEDQLSHLRQYEKSIVNY 681

Query: 543  RKLAMEVDKCSQELQQNMIFETPNCRYSMETLRVSWEQLQSSMRRSKSEIEDQILTRDSK 722
            +    +++   Q +Q+ +IF+  +  Y+ME +RV WEQL +++ R+ +E+E+QILTRD+K
Sbjct: 682  KPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAK 741

Query: 723  GISQSQMDEFRRCFNHFDKNKTRTLEPKEFKACLVSLGCNL-KEEKGEADFAKIMSEVDP 899
            GISQ QM+EFR  FNHFD++ + TL P+EFKACL+SLG ++  + +GEA+FA+IMS VDP
Sbjct: 742  GISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDP 801

Query: 900  NRSGVVTFGAFIDYMAKETTEQDTLEQILQSFKVLCQDRDYITAEELRRELPSAEAEYCI 1079
            NR GVVTF AFID+M++ET + DT +Q++ SFK+L  D++YIT +ELRRELP  +AEYCI
Sbjct: 802  NRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITMDELRRELPPDQAEYCI 861

Query: 1080 ANMAPY--PDGGEGALDYKLFASSLYGHSDL 1166
            A MAPY  PD   GALDY  F+++LYG SDL
Sbjct: 862  ARMAPYTGPDSVPGALDYMSFSTALYGESDL 892

 Score = 37.7 bits (86), Expect = 0.074
 Identities = 41/240 (17%), Positives = 102/240 (42%), Gaps = 11/240 (4%)
 Frame = +3

Query: 9   EEIDQMQLDYAKKIAPFYNWIEQAKEDLQDSHILLYIDEVKILIEKQDEFKKSMENAKLE 188
           +E +Q+  DY K  +    WI +    L++    +  + +  + +K ++F+        +
Sbjct: 270 QENEQLMEDYEKLASDLLEWIRRTIPWLENR---VPENTMHAMQQKLEDFR--------D 318

Query: 189 YNMLNQVDSQIKNRALENNLN------QISENPYTLLSQTALSVE*NK----LSDLLPLR 338
           Y  L++     +   LE N N      ++S  P  + S+  +  + N     L  +    
Sbjct: 319 YRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNAWGCLEQVEKGY 378

Query: 339 DEFLQKELSQQTKNEKLRENFGSLANKLGPWIDEKQQFINYLS-SGENVSTLESQKSQIE 515
           +E+L  E+ +  + + L E F   A+    W D K+  +         +S +++   + E
Sbjct: 379 EEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHE 438

Query: 516 HLETEINEYRKLAMEVDKCSQELQQNMIFETPNCRYSMETLRVSWEQLQSSMRRSKSEIE 695
             E+++  ++    ++   +QEL +   +++P+     + +   W+ L +  ++ +  +E
Sbjct: 439 AFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALE 498
>sp|P05094|ACTN1_CHICK Alpha-actinin 1 (Alpha-actinin cytoskeletal isoform) (Non-muscle
            alpha-actinin 1) (F-actin cross linking protein)
          Length = 893

 Score =  353 bits (905), Expect = 8e-97
 Identities = 180/391 (46%), Positives = 268/391 (68%), Gaps = 3/391 (0%)
 Frame = +3

Query: 3    LLEEIDQMQLDYAKKIAPFYNWIEQAKEDLQDSHILLYIDEVKILIEKQDEFKKSMENAK 182
            LLE IDQ+ L+YAK+ APF NW+E A EDLQD+ I+  I+E++ L    ++FK ++ +A 
Sbjct: 504  LLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDAD 563

Query: 183  LEYNMLNQVDSQIKNRALENNLNQISENPYTLLSQTALSVE*NKLSDLLPLRDEFLQKEL 362
             E   +  + +++       ++N    NPYT ++   ++ +   +  L+P RD+ L +E 
Sbjct: 564  KERQAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWEHVRQLVPRRDQALMEEH 623

Query: 363  SQQTKNEKLRENFGSLANKLGPWIDEKQQFINYLSSGENVSTLESQKSQIEHLETEINEY 542
            ++Q +NE+LR+ FG+ AN +GPWI  K + I  +S  E   TLE Q + +   E  I  Y
Sbjct: 624  ARQQQNERLRKQFGAQANVIGPWIQTKMEEIGRISI-EMHGTLEDQLNHLRQYEKSIVNY 682

Query: 543  RKLAMEVDKCSQELQQNMIFETPNCRYSMETLRVSWEQLQSSMRRSKSEIEDQILTRDSK 722
            +    +++   Q++Q+ +IF+  +  Y+ME +RV WEQL +++ R+ +E+E+QILTRD+K
Sbjct: 683  KPKIDQLEGDHQQIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAK 742

Query: 723  GISQSQMDEFRRCFNHFDKNKTRTLEPKEFKACLVSLGCNL-KEEKGEADFAKIMSEVDP 899
            GISQ QM+EFR  FNHFD++ + TL P+EFKACL+SLG ++  + +GEA+FA+IMS VDP
Sbjct: 743  GISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDAQGEAEFARIMSIVDP 802

Query: 900  NRSGVVTFGAFIDYMAKETTEQDTLEQILQSFKVLCQDRDYITAEELRRELPSAEAEYCI 1079
            NR GVVTF AFID+M++ET + DT +Q++ SFK+L  D++YIT +ELRRELP  +AEYCI
Sbjct: 803  NRMGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITVDELRRELPPDQAEYCI 862

Query: 1080 ANMAPY--PDGGEGALDYKLFASSLYGHSDL 1166
            A MAPY   D   GALDY  F+++LYG SDL
Sbjct: 863  ARMAPYNGRDAVPGALDYMSFSTALYGESDL 893

 Score = 37.0 bits (84), Expect = 0.13
 Identities = 41/240 (17%), Positives = 101/240 (42%), Gaps = 11/240 (4%)
 Frame = +3

Query: 9   EEIDQMQLDYAKKIAPFYNWIEQAKEDLQDSHILLYIDEVKILIEKQDEFKKSMENAKLE 188
           +E +Q+  DY K  +    WI +    L++       + ++ + +K ++F+        +
Sbjct: 271 QENEQLMEDYEKLASDLLEWIRRTIPWLENR---APENTMQAMQQKLEDFR--------D 319

Query: 189 YNMLNQVDSQIKNRALENNLN------QISENPYTLLSQTALSVE*NK----LSDLLPLR 338
           Y  L++     +   LE N N      ++S  P  + S+  +  + N     L       
Sbjct: 320 YRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDINNAWGGLEQAEKGY 379

Query: 339 DEFLQKELSQQTKNEKLRENFGSLANKLGPWIDEKQQFINYLS-SGENVSTLESQKSQIE 515
           +E+L  E+ +  + + L E F   A+    W D K+  +         +S +++   + E
Sbjct: 380 EEWLLNEIRRLERLDHLAEKFRQKASIHESWTDGKEAMLQQKDYETATLSEIKALLKKHE 439

Query: 516 HLETEINEYRKLAMEVDKCSQELQQNMIFETPNCRYSMETLRVSWEQLQSSMRRSKSEIE 695
             E+++  ++    ++   +QEL +   +++P+     + +   W+ L +  ++ +  +E
Sbjct: 440 AFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALE 499

 Score = 31.6 bits (70), Expect = 5.3
 Identities = 22/85 (25%), Positives = 45/85 (52%), Gaps = 3/85 (3%)
 Frame = +3

Query: 354 KELSQQTKNEKLRENFGSLANKLGPWIDEKQQFINYLSSGENVSTLESQKSQIEHLETEI 533
           K L+   +NE+L E++  LA+ L  WI   ++ I +L +    +T+++ + ++E    + 
Sbjct: 265 KVLAVNQENEQLMEDYEKLASDLLEWI---RRTIPWLENRAPENTMQAMQQKLE----DF 317

Query: 534 NEYRKL---AMEVDKCSQELQQNMI 599
            +YR+L       +KC  E+  N +
Sbjct: 318 RDYRRLHKPPKVQEKCQLEINFNTL 342
>sp|Q7TPR4|ACTN1_MOUSE Alpha-actinin 1 (Alpha-actinin cytoskeletal isoform) (Non-muscle
            alpha-actinin 1) (F-actin cross linking protein)
          Length = 892

 Score =  352 bits (904), Expect = 1e-96
 Identities = 182/391 (46%), Positives = 268/391 (68%), Gaps = 3/391 (0%)
 Frame = +3

Query: 3    LLEEIDQMQLDYAKKIAPFYNWIEQAKEDLQDSHILLYIDEVKILIEKQDEFKKSMENAK 182
            LLE IDQ+ L+YAK+ APF NW+E A EDLQD+ I+  I+E++ L    ++FK ++ +A 
Sbjct: 503  LLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDAD 562

Query: 183  LEYNMLNQVDSQIKNRALENNLNQISENPYTLLSQTALSVE*NKLSDLLPLRDEFLQKEL 362
             E   +  + +++       ++N    NPYT ++   ++ + + +  L+P RD+ L +E 
Sbjct: 563  KERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEH 622

Query: 363  SQQTKNEKLRENFGSLANKLGPWIDEKQQFINYLSSGENVSTLESQKSQIEHLETEINEY 542
            ++Q  NE+LR+ FG+ AN +GPWI  K + I  +S  E   TLE Q S +   E  I  Y
Sbjct: 623  ARQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISI-EMHGTLEDQLSHLRQYEKSIVNY 681

Query: 543  RKLAMEVDKCSQELQQNMIFETPNCRYSMETLRVSWEQLQSSMRRSKSEIEDQILTRDSK 722
            +    +++   Q +Q+ +IF+  +  Y+ME +RV WEQL +++ R+ +E+E+QILTRD+K
Sbjct: 682  KPKIDQLECDHQLIQEALIFDNKHTNYNMEHIRVGWEQLLTTIARTINEVENQILTRDAK 741

Query: 723  GISQSQMDEFRRCFNHFDKNKTRTLEPKEFKACLVSLGCNL-KEEKGEADFAKIMSEVDP 899
            GISQ QM+EFR  FNHFD++ + TL P+EFKACL+SLG ++  + +GEA+FA+IMS VDP
Sbjct: 742  GISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDP 801

Query: 900  NRSGVVTFGAFIDYMAKETTEQDTLEQILQSFKVLCQDRDYITAEELRRELPSAEAEYCI 1079
            NR GVVTF AFID+M++ET + DT +Q++ SFK+L  D++YIT +ELRRELP  +AEYCI
Sbjct: 802  NRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITEDELRRELPPDQAEYCI 861

Query: 1080 ANMAPY--PDGGEGALDYKLFASSLYGHSDL 1166
            A MAPY  PD   GALDY  F+++LYG SDL
Sbjct: 862  ARMAPYAGPDSVPGALDYMSFSTALYGESDL 892

 Score = 37.4 bits (85), Expect = 0.097
 Identities = 41/240 (17%), Positives = 101/240 (42%), Gaps = 11/240 (4%)
 Frame = +3

Query: 9   EEIDQMQLDYAKKIAPFYNWIEQAKEDLQDSHILLYIDEVKILIEKQDEFKKSMENAKLE 188
           +E +Q+  DY K  +    WI +    L++    +  + +  + +K ++F+        +
Sbjct: 270 QENEQLMEDYEKLASDLLEWIRRTIPWLENR---VPENTMHAMQQKLEDFR--------D 318

Query: 189 YNMLNQVDSQIKNRALENNLN------QISENPYTLLSQTALSVE*NKLSDLLPLRD--- 341
           Y  L++     +   LE N N      ++S  P  + S+  +  + N     L   +   
Sbjct: 319 YRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNAWGCLEQAEKGY 378

Query: 342 -EFLQKELSQQTKNEKLRENFGSLANKLGPWIDEKQQFINYLS-SGENVSTLESQKSQIE 515
            E+L  E+ +  + + L E F   A+    W D K+  +         +S +++   + E
Sbjct: 379 EEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHE 438

Query: 516 HLETEINEYRKLAMEVDKCSQELQQNMIFETPNCRYSMETLRVSWEQLQSSMRRSKSEIE 695
             E+++  ++    ++   +QEL +   +++P+     + +   W+ L +  ++ +  +E
Sbjct: 439 AFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALE 498
>sp|Q90734|ACTN4_CHICK Alpha-actinin 4 (Non-muscle alpha-actinin 4) (F-actin cross linking
            protein)
          Length = 904

 Score =  351 bits (901), Expect = 2e-96
 Identities = 183/390 (46%), Positives = 263/390 (67%), Gaps = 3/390 (0%)
 Frame = +3

Query: 6    LEEIDQMQLDYAKKIAPFYNWIEQAKEDLQDSHILLYIDEVKILIEKQDEFKKSMENAKL 185
            LE ID++ L+YAK+ APF NW+E A EDLQD  I+  I+E++ LI   D+FK ++ +A  
Sbjct: 516  LETIDELHLEYAKRAAPFNNWMESAMEDLQDMFIVHTIEEIEGLIAAHDQFKATLPDADR 575

Query: 186  EYNMLNQVDSQIKNRALENNLNQISENPYTLLSQTALSVE*NKLSDLLPLRDEFLQKELS 365
            E   +  +  + +  A  +++     NPYT ++   ++ +  ++  L+P RD  LQ E S
Sbjct: 576  EREAILGIQREAQRIADLHSIKLSGNNPYTSVTPQVINSKWERVQQLVPTRDRALQDEQS 635

Query: 366  QQTKNEKLRENFGSLANKLGPWIDEKQQFINYLSSGENVSTLESQKSQIEHLETEINEYR 545
            +Q  NE+LR  F   AN +GPW+  K + I  +S  E   TLE Q   ++H E  I +Y+
Sbjct: 636  RQQCNERLRRQFAGQANIVGPWMQTKMEEIGRISI-EMHGTLEDQLQHLKHYEQSIVDYK 694

Query: 546  KLAMEVDKCSQELQQNMIFETPNCRYSMETLRVSWEQLQSSMRRSKSEIEDQILTRDSKG 725
                 ++   Q +++ +IF+  +  Y+ME +RV WEQL +++ R+ +E+E+QILTRD+KG
Sbjct: 695  PNLELLEHEHQLVEEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKG 754

Query: 726  ISQSQMDEFRRCFNHFDKNKTRTLEPKEFKACLVSLGCNLKEEK-GEADFAKIMSEVDPN 902
            ISQ QM EFR  FNHFDK+    L P+EFKACL+SLG +++ ++ G+A+F +IMS VDPN
Sbjct: 755  ISQEQMQEFRASFNHFDKDHCGALGPEEFKACLISLGYDVENDRQGDAEFNRIMSLVDPN 814

Query: 903  RSGVVTFGAFIDYMAKETTEQDTLEQILQSFKVLCQDRDYITAEELRRELPSAEAEYCIA 1082
             SG VTF AFID+M++ETT+ DT +Q++ SFKVL  D++YITAEELRRELP  +AEYCIA
Sbjct: 815  GSGSVTFQAFIDFMSRETTDTDTADQVIASFKVLAGDKNYITAEELRRELPPEQAEYCIA 874

Query: 1083 NMAPY--PDGGEGALDYKLFASSLYGHSDL 1166
             MAPY  PD   GALDYK F+++LYG SDL
Sbjct: 875  RMAPYRGPDAAPGALDYKSFSTALYGESDL 904

 Score = 39.7 bits (91), Expect = 0.020
 Identities = 48/246 (19%), Positives = 103/246 (41%), Gaps = 10/246 (4%)
 Frame = +3

Query: 9   EEIDQMQLDYAKKIAPFYNWIEQAKEDLQDSHILLYIDEVKILIEKQDEFKKSMENAKLE 188
           +E + +  DY K  +    WI +    L+D      I E++  +E   ++++  +  K++
Sbjct: 282 QENEHLMEDYEKLASDLLEWIRRTIPWLEDRSPQKTIQEMQQKLEDFRDYRRVHKPPKVQ 341

Query: 189 YNMLNQVDSQIKNRALENNLNQISENPYTLLSQTALSVE*N----KLSDLLPLRDEFLQK 356
                +   +I    L+  L ++S  P  + S+  +  + N     L       +E+L  
Sbjct: 342 ----EKCQLEINFNTLQTKL-RLSNRPAFMPSEGRMVSDINTGWQHLEQAEKGYEEWLLN 396

Query: 357 ELSQQTKNEKLRENFGSLANKLGPWIDEKQQFINYLSSGENVSTLESQKSQI---EHLET 527
           E+ +    + L E F   A+    W + K+  +         +TL   K+ I   E  E+
Sbjct: 397 EIRRLEPLDHLAEKFRQKASIHEAWTEGKEAMLK--QKDYETATLSDIKALIRKHEAFES 454

Query: 528 EINEYRKLAMEVDKCSQELQQNMIFETPNCRYSMETLRVSWEQLQS---SMRRSKSEIED 698
           ++  ++    ++   +QEL +   +++P+     + +   W+ L S   S R +  + E 
Sbjct: 455 DLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDVLGSLTHSRREALEKTEK 514

Query: 699 QILTRD 716
           Q+ T D
Sbjct: 515 QLETID 520
>sp|P18091|ACTN_DROME Alpha-actinin, sarcomeric (F-actin cross linking protein)
          Length = 924

 Score =  344 bits (882), Expect = 4e-94
 Identities = 172/391 (43%), Positives = 263/391 (67%), Gaps = 3/391 (0%)
 Frame = +3

Query: 3    LLEEIDQMQLDYAKKIAPFYNWIEQAKEDLQDSHILLYIDEVKILIEKQDEFKKSMENAK 182
            +LE+ID + L++AK+ APF NW++  +EDL D  I+  ++E++ LI+  D+FK ++  A 
Sbjct: 535  ILEKIDILHLEFAKRAAPFNNWLDGTREDLVDMFIVHTMEEIQGLIQAHDQFKATLGEAD 594

Query: 183  LEYNMLNQVDSQIKNRALENNLNQISENPYTLLSQTALSVE*NKLSDLLPLRDEFLQKEL 362
             E+N++  +  ++++   ++ +    ENPYT L+   ++ + + +  L+P RD+ L  EL
Sbjct: 595  KEFNLIVNLVREVESIVKQHQIPGGLENPYTTLTANDMTRKWSDVRQLVPQRDQTLANEL 654

Query: 363  SQQTKNEKLRENFGSLANKLGPWIDEKQQFINYLSSGENVSTLESQKSQIEHLETEINEY 542
             +Q  NE LR  F   AN +GPWI+ +   +  +  G   S LE Q  +++  E  +  Y
Sbjct: 655  RKQQNNEMLRRQFAEKANIVGPWIERQMDAVTAIGMGLQGS-LEDQLHRLKEYEQAVYAY 713

Query: 543  RKLAMEVDKCSQELQQNMIFETPNCRYSMETLRVSWEQLQSSMRRSKSEIEDQILTRDSK 722
            +    E++K  Q +Q++MIFE     Y+METLRV WEQL +S+ R+ +E+E+QILTRDSK
Sbjct: 714  KPNIEELEKIHQAVQESMIFENRYTNYTMETLRVGWEQLLTSINRNINEVENQILTRDSK 773

Query: 723  GISQSQMDEFRRCFNHFDKNKTRTLEPKEFKACLVSLGCNL-KEEKGEADFAKIMSEVDP 899
            GISQ Q++EFR  FNHFDKN+T  L P+EFK+CLVSLG ++ K+ +G+ DF +I++ VDP
Sbjct: 774  GISQEQLNEFRSSFNHFDKNRTGRLSPEEFKSCLVSLGYSIGKDRQGDLDFQRILAVVDP 833

Query: 900  NRSGVVTFGAFIDYMAKETTEQDTLEQILQSFKVLCQDRDYITAEELRRELPSAEAEYCI 1079
            N +G V F AF+D+M +E+T+ DT EQ++ SF++L  D+ YI  +ELRRELP  +AEYCI
Sbjct: 834  NNTGYVHFDAFLDFMTRESTDTDTAEQVIDSFRILAADKPYILPDELRRELPPDQAEYCI 893

Query: 1080 ANMAPY--PDGGEGALDYKLFASSLYGHSDL 1166
              M PY  P+G  GALDY  F+++LYG +DL
Sbjct: 894  QRMPPYKGPNGVPGALDYMSFSTALYGETDL 924

 Score = 31.2 bits (69), Expect = 6.9
 Identities = 35/196 (17%), Positives = 81/196 (41%), Gaps = 15/196 (7%)
 Frame = +3

Query: 354 KELSQQTKNEKLRENFGSLANKLGPWIDEKQQFINYLSSGENVSTLESQKSQI-----EH 518
           K L    +NE+L E +  LA+ L  WI     ++N   +  +++ ++ +  +      +H
Sbjct: 296 KVLKVNQENERLMEEYERLASDLLEWIRRTMPWLNSRQADNSLAGVQKKLEEYRTYRRKH 355

Query: 519 LETEINEYRKLAMEVDKCSQELQ-QNMIFETPNCRYSMETLRVSWEQLQSSMRRSKSEIE 695
               + +  KL    +    +L+  N     P    ++  +  SW+ L+     ++   E
Sbjct: 356 KPPRVEQKAKLETNFNTLQTKLRLSNRPAYLPTEGKTVSDISNSWKGLE----LAEKAFE 411

Query: 696 DQILTRDSKGISQSQMDEFRRCFNH-------FDKNKTRTLEPKEFKACLVS--LGCNLK 848
           + +L   ++ +   +++   + F H       + + K   L+ ++F+ C ++       K
Sbjct: 412 EWLL---AETMRLERLEHLAQKFKHKADAHEDWTRGKEEMLQSQDFRQCKLNELKALKKK 468

Query: 849 EEKGEADFAKIMSEVD 896
            E  E+D A     V+
Sbjct: 469 HEAFESDLAAHQDRVE 484
>sp|Q08043|ACTN3_HUMAN Alpha-actinin 3 (Alpha actinin skeletal muscle isoform 3) (F-actin
            cross linking protein)
          Length = 901

 Score =  342 bits (877), Expect = 1e-93
 Identities = 174/390 (44%), Positives = 258/390 (66%), Gaps = 2/390 (0%)
 Frame = +3

Query: 3    LLEEIDQMQLDYAKKIAPFYNWIEQAKEDLQDSHILLYIDEVKILIEKQDEFKKSMENAK 182
            LLE IDQ+QL++A++ APF NW++ A EDLQD  ++  ++E + L+   D+FK ++  A 
Sbjct: 517  LLETIDQLQLEFARRAAPFNNWLDGAVEDLQDVWLVHSVEETQSLLTAHDQFKATLPEAD 576

Query: 183  LEYNMLNQVDSQIKNRALENNLNQISENPYTLLSQTALSVE*NKLSDLLPLRDEFLQKEL 362
             E   +  +  +I+       L   S NPY  LS   ++ + + +  L+P RD+ LQ+EL
Sbjct: 577  RERGAIMGIQGEIQKICQTYGLRPCSTNPYITLSPQDINTKWDMVRKLVPSRDQTLQEEL 636

Query: 363  SQQTKNEKLRENFGSLANKLGPWIDEKQQFINYLSSGENVSTLESQKSQIEHLETEINEY 542
            ++Q  NE+LR  F + AN +GPWI  K + +  L++G    +LE Q + +   E  I  Y
Sbjct: 637  ARQQVNERLRRQFAAQANAIGPWIQAKVEEVGRLAAG-LAGSLEEQMAGLRQQEQNIINY 695

Query: 543  RKLAMEVDKCSQELQQNMIFETPNCRYSMETLRVSWEQLQSSMRRSKSEIEDQILTRDSK 722
            +     ++   Q LQ++++F+  +  YSME +RV WEQL +S+ R+ +E+E+Q+LTRD+K
Sbjct: 696  KTNIDRLEGDHQLLQESLVFDNKHTVYSMEHIRVGWEQLLTSIARTINEVENQVLTRDAK 755

Query: 723  GISQSQMDEFRRCFNHFDKNKTRTLEPKEFKACLVSLGCNLKEEKGEADFAKIMSEVDPN 902
            G+SQ Q++EFR  FNHFD+ +   +EP +F+ACL+S+G +L    GE +FA+IM+ VDPN
Sbjct: 756  GLSQEQLNEFRASFNHFDRKRNGMMEPDDFRACLISMGYDL----GEVEFARIMTMVDPN 811

Query: 903  RSGVVTFGAFIDYMAKETTEQDTLEQILQSFKVLCQDRDYITAEELRRELPSAEAEYCIA 1082
             +GVVTF AFID+M +ET E DT EQ++ SFK+L  D++YIT EELRRELP+ +AEYCI 
Sbjct: 812  AAGVVTFQAFIDFMTRETAETDTTEQVVASFKILAGDKNYITPEELRRELPAKQAEYCIR 871

Query: 1083 NMAPYPDGG--EGALDYKLFASSLYGHSDL 1166
             M PY   G   GALDY  F+S+LYG SDL
Sbjct: 872  RMVPYKGSGAPAGALDYVAFSSALYGESDL 901
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 134,274,488
Number of Sequences: 369166
Number of extensions: 2533767
Number of successful extensions: 8951
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 8077
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8758
length of database: 68,354,980
effective HSP length: 114
effective length of database: 47,295,190
effective search space used: 15276346370
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00476

  1. Dr_sW_012_K24
  2. Dr_sW_024_F02
  3. Dr_sW_015_G21
  4. Dr_sW_021_F06