Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00431 (745 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P61619|S61A1_HUMAN Protein transport protein Sec61 alpha... 340 2e-93 sp|Q9JLR1|S61A2_MOUSE Protein transport protein Sec61 alpha... 339 4e-93 sp|Q90ZM2|S61A1_BRARE Protein transport protein Sec61 alpha... 339 4e-93 sp|Q8AY32|SC61A_GADOC Protein transport protein Sec61 alpha... 339 4e-93 sp|Q98SN8|S61A2_ONCMY Protein transport protein Sec61 alpha... 339 4e-93 sp|P38377|S61A1_CANFA Protein transport protein Sec61 alpha... 338 7e-93 sp|Q7T278|SC61A_HARAN Protein transport protein Sec61 alpha... 338 7e-93 sp|Q8AY36|SC61A_PAGBO Protein transport protein Sec61 alpha... 338 7e-93 sp|Q8AY33|SC61A_BORSA Protein transport protein Sec61 alpha... 337 2e-92 sp|Q90YL4|S61A2_BRARE Protein transport protein Sec61 alpha... 337 2e-92
>sp|P61619|S61A1_HUMAN Protein transport protein Sec61 alpha subunit isoform 1 (Sec61 alpha-1) sp|P61621|S61A1_RAT Protein transport protein Sec61 alpha subunit isoform 1 (Sec61 alpha-1) sp|P61620|S61A1_MOUSE Protein transport protein Sec61 alpha subunit isoform 1 (Sec61 alpha-1) Length = 476 Score = 340 bits (873), Expect = 2e-93 Identities = 168/207 (81%), Positives = 189/207 (91%), Gaps = 2/207 (0%) Frame = +1 Query: 1 RYRGQHSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG 180 RYRGQ+++YPIKLFYTSNIPIILQSALVSNLYVISQMLS +F GNL+++LLGTWSD +G Sbjct: 271 RYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLGTWSDTSSG 330 Query: 181 --SRSVPIGGICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDV 354 +R+ P+GG+CYY+SPP+S ++ DPVH +YI FMLGSCAFFSKTWI+VSGSSAKDV Sbjct: 331 GPARAYPVGGLCYYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDV 390 Query: 355 AKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 534 AKQLKEQQMVMRGHRE SM+HELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA Sbjct: 391 AKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 450 Query: 535 VTIIYQYFEIFVKEQNEMGGSMSTLLF 615 VTIIYQYFEIFVKEQ+E+ GSM LLF Sbjct: 451 VTIIYQYFEIFVKEQSEV-GSMGALLF 476
>sp|Q9JLR1|S61A2_MOUSE Protein transport protein Sec61 alpha subunit isoform 2 (Sec61 alpha-2) sp|Q9H9S3|S61A2_HUMAN Protein transport protein Sec61 alpha subunit isoform 2 (Sec61 alpha-2) Length = 476 Score = 339 bits (870), Expect = 4e-93 Identities = 169/207 (81%), Positives = 186/207 (89%), Gaps = 2/207 (0%) Frame = +1 Query: 1 RYRGQHSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG 180 RYRGQ+SSYPIKLFYTSNIPIILQSALVSNLYVISQMLS +F GN ++NLLG W+D G Sbjct: 271 RYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSVRFSGNFLVNLLGQWADVSGG 330 Query: 181 --SRSVPIGGICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDV 354 +RS P+GG+CYY+SPP+S+ A+F DPVH +YI FMLGSCAFFSKTWI+VSGSSAKDV Sbjct: 331 GPARSYPVGGLCYYLSPPESMGAIFEDPVHVVVYIIFMLGSCAFFSKTWIEVSGSSAKDV 390 Query: 355 AKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 534 AKQLKEQQMVMRGHR+ SM+HELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA Sbjct: 391 AKQLKEQQMVMRGHRDTSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 450 Query: 535 VTIIYQYFEIFVKEQNEMGGSMSTLLF 615 VTIIYQYFEIFVKEQ E+GG M L F Sbjct: 451 VTIIYQYFEIFVKEQAEVGG-MGALFF 476
>sp|Q90ZM2|S61A1_BRARE Protein transport protein Sec61 alpha subunit isoform A Length = 476 Score = 339 bits (870), Expect = 4e-93 Identities = 167/207 (80%), Positives = 187/207 (90%), Gaps = 2/207 (0%) Frame = +1 Query: 1 RYRGQHSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG 180 RYRGQ+++YPIKLFYTSNIPIILQSALVSNLYVISQMLS +F GN ++NLLGTWSD +G Sbjct: 271 RYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDTSSG 330 Query: 181 --SRSVPIGGICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDV 354 +R+ P+GG+CYY+SPP+S ++ DPVH IYI FMLGSCAFFSKTWI+VSGSSAKDV Sbjct: 331 GPARAYPVGGLCYYLSPPESFGSVLDDPVHAVIYIVFMLGSCAFFSKTWIEVSGSSAKDV 390 Query: 355 AKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 534 AKQLKEQQMVMRGHRE SM+HELNRYIPTAAAFGGLCIG LSV+ADFLGAIGSGTGILLA Sbjct: 391 AKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLA 450 Query: 535 VTIIYQYFEIFVKEQNEMGGSMSTLLF 615 VTIIYQYFEIFVKEQ+E+ GSM LLF Sbjct: 451 VTIIYQYFEIFVKEQSEV-GSMGALLF 476
>sp|Q8AY32|SC61A_GADOC Protein transport protein Sec61 alpha subunit Length = 476 Score = 339 bits (870), Expect = 4e-93 Identities = 168/207 (81%), Positives = 185/207 (89%), Gaps = 2/207 (0%) Frame = +1 Query: 1 RYRGQHSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG 180 RYRGQ+++YPIKLFYTSNIPIILQSALVSNLYVISQMLS +F GN ++NLLGTWSD G Sbjct: 271 RYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDTSTG 330 Query: 181 --SRSVPIGGICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDV 354 +R+ P+GG+CYY SPP+S ++ DPVH IYI FMLGSCAFFSKTWI+VSGSSAKDV Sbjct: 331 GPARAYPVGGLCYYFSPPESFGSVLDDPVHASIYIVFMLGSCAFFSKTWIEVSGSSAKDV 390 Query: 355 AKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 534 AKQLKEQQMVMRGHRE SM+HELNRYIPTAAAFGGLCIG LSV+ADFLGAIGSGTGILLA Sbjct: 391 AKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLA 450 Query: 535 VTIIYQYFEIFVKEQNEMGGSMSTLLF 615 VTIIYQYFEIFVKEQ+EM GSM LLF Sbjct: 451 VTIIYQYFEIFVKEQSEM-GSMGALLF 476
>sp|Q98SN8|S61A2_ONCMY Protein transport protein Sec61 alpha subunit isoform B Length = 476 Score = 339 bits (870), Expect = 4e-93 Identities = 167/207 (80%), Positives = 186/207 (89%), Gaps = 2/207 (0%) Frame = +1 Query: 1 RYRGQHSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG 180 RYRGQ+++YPIKLFYTSNIPIILQSALVSNLYVISQMLS +F GN ++NLLGTWSD +G Sbjct: 271 RYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDTSSG 330 Query: 181 --SRSVPIGGICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDV 354 +R+ P+GG+CYY SPP+S ++ DP+H IYI FMLGSCAFFSKTWI+VSGSSAKDV Sbjct: 331 GPARAYPVGGLCYYFSPPESFGSVLDDPIHAAIYICFMLGSCAFFSKTWIEVSGSSAKDV 390 Query: 355 AKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 534 AKQLKEQQMVMRGHRE SM+HELNRYIPTAAAFGGLCIG LSV+ADFLGAIGSGTGILLA Sbjct: 391 AKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLA 450 Query: 535 VTIIYQYFEIFVKEQNEMGGSMSTLLF 615 VTIIYQYFEIFVKEQ+EM GSM LLF Sbjct: 451 VTIIYQYFEIFVKEQSEM-GSMGALLF 476
>sp|P38377|S61A1_CANFA Protein transport protein Sec61 alpha subunit isoform 1 (Sec61 alpha-1) Length = 476 Score = 338 bits (868), Expect = 7e-93 Identities = 167/207 (80%), Positives = 189/207 (91%), Gaps = 2/207 (0%) Frame = +1 Query: 1 RYRGQHSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG 180 RYRGQ+++YPIKLFYTSNIPIILQSALVSNLYVISQMLS +F GNL+++LLGTWSD +G Sbjct: 271 RYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLGTWSDTSSG 330 Query: 181 --SRSVPIGGICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDV 354 +R+ P+GG+C+Y+SPP+S ++ DPVH +YI FMLGSCAFFSKTWI+VSGSSAKDV Sbjct: 331 GPARAYPVGGLCHYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDV 390 Query: 355 AKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 534 AKQLKEQQMVMRGHRE SM+HELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA Sbjct: 391 AKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 450 Query: 535 VTIIYQYFEIFVKEQNEMGGSMSTLLF 615 VTIIYQYFEIFVKEQ+E+ GSM LLF Sbjct: 451 VTIIYQYFEIFVKEQSEV-GSMGALLF 476
>sp|Q7T278|SC61A_HARAN Protein transport protein Sec61 alpha subunit sp|Q7T277|SC61A_DISMA Protein transport protein Sec61 alpha subunit Length = 476 Score = 338 bits (868), Expect = 7e-93 Identities = 167/207 (80%), Positives = 186/207 (89%), Gaps = 2/207 (0%) Frame = +1 Query: 1 RYRGQHSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG 180 RYRGQ+++YPIKLFYTSNIPIILQSALVSNLYVISQMLS +F GN ++NLLGTWSD +G Sbjct: 271 RYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDATSG 330 Query: 181 --SRSVPIGGICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDV 354 +R+ P+ G+CYY+SPP+S ++ DPVH IYI FMLGSCAFFSKTWI+VSGSSAKDV Sbjct: 331 GPARAYPVAGLCYYLSPPESFGSVLDDPVHAAIYIVFMLGSCAFFSKTWIEVSGSSAKDV 390 Query: 355 AKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 534 AKQLKEQQMVMRGHRE SM+HELNRYIPTAAAFGGLCIG LSV+ADFLGAIGSGTGILLA Sbjct: 391 AKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLA 450 Query: 535 VTIIYQYFEIFVKEQNEMGGSMSTLLF 615 VTIIYQYFEIFVKEQ+EM GSM LLF Sbjct: 451 VTIIYQYFEIFVKEQSEM-GSMGALLF 476
>sp|Q8AY36|SC61A_PAGBO Protein transport protein Sec61 alpha subunit sp|Q8AY35|SC61A_NOTAN Protein transport protein Sec61 alpha subunit Length = 476 Score = 338 bits (868), Expect = 7e-93 Identities = 167/207 (80%), Positives = 186/207 (89%), Gaps = 2/207 (0%) Frame = +1 Query: 1 RYRGQHSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG 180 RYRGQ+++YPIKLFYTSNIPIILQSALVSNLYVISQMLS +F GN ++NLLGTWSD +G Sbjct: 271 RYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDATSG 330 Query: 181 --SRSVPIGGICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDV 354 +R+ P+ G+CYY+SPP+S ++ DPVH IYI FMLGSCAFFSKTWI+VSGSSAKDV Sbjct: 331 GPARAYPVAGLCYYLSPPESFGSVLDDPVHAAIYIVFMLGSCAFFSKTWIEVSGSSAKDV 390 Query: 355 AKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 534 AKQLKEQQMVMRGHRE SM+HELNRYIPTAAAFGGLCIG LSV+ADFLGAIGSGTGILLA Sbjct: 391 AKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLA 450 Query: 535 VTIIYQYFEIFVKEQNEMGGSMSTLLF 615 VTIIYQYFEIFVKEQ+EM GSM LLF Sbjct: 451 VTIIYQYFEIFVKEQSEM-GSMGALLF 476
>sp|Q8AY33|SC61A_BORSA Protein transport protein Sec61 alpha subunit Length = 476 Score = 337 bits (864), Expect = 2e-92 Identities = 167/207 (80%), Positives = 185/207 (89%), Gaps = 2/207 (0%) Frame = +1 Query: 1 RYRGQHSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG 180 RYRGQ+++YPIKLFYTSNIPIILQSALVSNLYVISQMLS +F GN I+NLLGTWSD G Sbjct: 271 RYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFIVNLLGTWSDTSTG 330 Query: 181 --SRSVPIGGICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDV 354 +R+ P+GG+CY++SPP+S ++ DPVH IYI FMLGSCAFFSKTWI+VSGSSAKDV Sbjct: 331 GPARAYPVGGLCYFLSPPESFGSVLDDPVHAAIYIVFMLGSCAFFSKTWIEVSGSSAKDV 390 Query: 355 AKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 534 AKQLKEQQMVMRGHRE SM+HELNRYIPTAAAFGGLCIG LSV+ADFLGAIGSGTGILLA Sbjct: 391 AKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLA 450 Query: 535 VTIIYQYFEIFVKEQNEMGGSMSTLLF 615 VTIIYQYFEIFVKEQ+EM GSM L F Sbjct: 451 VTIIYQYFEIFVKEQSEM-GSMGGLFF 476
>sp|Q90YL4|S61A2_BRARE Protein transport protein Sec61 alpha subunit isoform B Length = 476 Score = 337 bits (864), Expect = 2e-92 Identities = 165/207 (79%), Positives = 185/207 (89%), Gaps = 2/207 (0%) Frame = +1 Query: 1 RYRGQHSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG 180 RYRGQ+++YPIKLFYTSNIPIILQSALVSNLYVISQMLS +F GN ++NLLGTWSD G Sbjct: 271 RYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDTSTG 330 Query: 181 --SRSVPIGGICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDV 354 +R+ P+GG+CYY+SPP+S + DP+H IYI FMLGSCAFFSKTWI+VSGSSAKDV Sbjct: 331 GPARAYPVGGLCYYLSPPESFGTVLEDPIHAIIYIIFMLGSCAFFSKTWIEVSGSSAKDV 390 Query: 355 AKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 534 AKQLKEQQMVMRGHRE SM+HELNRYIPTAAAFGGLCIG LSV+ADFLGAIGSGTGILLA Sbjct: 391 AKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLA 450 Query: 535 VTIIYQYFEIFVKEQNEMGGSMSTLLF 615 VTIIYQYFEIFVKEQ+E+ GS+ LLF Sbjct: 451 VTIIYQYFEIFVKEQSEV-GSVGALLF 476
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 92,376,927 Number of Sequences: 369166 Number of extensions: 1977498 Number of successful extensions: 6837 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 6459 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6782 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 6728100400 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)