Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_P05
(719 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P61619|S61A1_HUMAN Protein transport protein Sec61 alpha... 323 4e-88
sp|Q90ZM2|S61A1_BRARE Protein transport protein Sec61 alpha... 322 8e-88
sp|Q8AY32|SC61A_GADOC Protein transport protein Sec61 alpha... 322 8e-88
sp|Q98SN8|S61A2_ONCMY Protein transport protein Sec61 alpha... 322 8e-88
sp|P38377|S61A1_CANFA Protein transport protein Sec61 alpha... 321 1e-87
sp|Q7T278|SC61A_HARAN Protein transport protein Sec61 alpha... 321 1e-87
sp|Q8AY36|SC61A_PAGBO Protein transport protein Sec61 alpha... 321 1e-87
sp|Q9JLR1|S61A2_MOUSE Protein transport protein Sec61 alpha... 319 4e-87
sp|Q8AY33|SC61A_BORSA Protein transport protein Sec61 alpha... 319 4e-87
sp|Q90YL4|S61A2_BRARE Protein transport protein Sec61 alpha... 319 4e-87
>sp|P61619|S61A1_HUMAN Protein transport protein Sec61 alpha subunit isoform 1 (Sec61
alpha-1)
sp|P61621|S61A1_RAT Protein transport protein Sec61 alpha subunit isoform 1 (Sec61
alpha-1)
sp|P61620|S61A1_MOUSE Protein transport protein Sec61 alpha subunit isoform 1 (Sec61
alpha-1)
Length = 476
Score = 323 bits (827), Expect = 4e-88
Identities = 161/197 (81%), Positives = 179/197 (90%), Gaps = 2/197 (1%)
Frame = +2
Query: 5 IKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG--SRSVPIGG 178
IKLFYTSNIPIILQSALVSNLYVISQMLS +F GNL+++LLGTWSD +G +R+ P+GG
Sbjct: 281 IKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGG 340
Query: 179 ICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMV 358
+CYY+SPP+S ++ DPVH +YI FMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMV
Sbjct: 341 LCYYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMV 400
Query: 359 MRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEI 538
MRGHRE SM+HELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEI
Sbjct: 401 MRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEI 460
Query: 539 FVKEQNEMGGSMSTLLF 589
FVKEQ+E+ GSM LLF
Sbjct: 461 FVKEQSEV-GSMGALLF 476
>sp|Q90ZM2|S61A1_BRARE Protein transport protein Sec61 alpha subunit isoform A
Length = 476
Score = 322 bits (824), Expect = 8e-88
Identities = 160/197 (81%), Positives = 177/197 (89%), Gaps = 2/197 (1%)
Frame = +2
Query: 5 IKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG--SRSVPIGG 178
IKLFYTSNIPIILQSALVSNLYVISQMLS +F GN ++NLLGTWSD +G +R+ P+GG
Sbjct: 281 IKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDTSSGGPARAYPVGG 340
Query: 179 ICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMV 358
+CYY+SPP+S ++ DPVH IYI FMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMV
Sbjct: 341 LCYYLSPPESFGSVLDDPVHAVIYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMV 400
Query: 359 MRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEI 538
MRGHRE SM+HELNRYIPTAAAFGGLCIG LSV+ADFLGAIGSGTGILLAVTIIYQYFEI
Sbjct: 401 MRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEI 460
Query: 539 FVKEQNEMGGSMSTLLF 589
FVKEQ+E+ GSM LLF
Sbjct: 461 FVKEQSEV-GSMGALLF 476
>sp|Q8AY32|SC61A_GADOC Protein transport protein Sec61 alpha subunit
Length = 476
Score = 322 bits (824), Expect = 8e-88
Identities = 161/197 (81%), Positives = 175/197 (88%), Gaps = 2/197 (1%)
Frame = +2
Query: 5 IKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG--SRSVPIGG 178
IKLFYTSNIPIILQSALVSNLYVISQMLS +F GN ++NLLGTWSD G +R+ P+GG
Sbjct: 281 IKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDTSTGGPARAYPVGG 340
Query: 179 ICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMV 358
+CYY SPP+S ++ DPVH IYI FMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMV
Sbjct: 341 LCYYFSPPESFGSVLDDPVHASIYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMV 400
Query: 359 MRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEI 538
MRGHRE SM+HELNRYIPTAAAFGGLCIG LSV+ADFLGAIGSGTGILLAVTIIYQYFEI
Sbjct: 401 MRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEI 460
Query: 539 FVKEQNEMGGSMSTLLF 589
FVKEQ+EM GSM LLF
Sbjct: 461 FVKEQSEM-GSMGALLF 476
>sp|Q98SN8|S61A2_ONCMY Protein transport protein Sec61 alpha subunit isoform B
Length = 476
Score = 322 bits (824), Expect = 8e-88
Identities = 160/197 (81%), Positives = 176/197 (89%), Gaps = 2/197 (1%)
Frame = +2
Query: 5 IKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG--SRSVPIGG 178
IKLFYTSNIPIILQSALVSNLYVISQMLS +F GN ++NLLGTWSD +G +R+ P+GG
Sbjct: 281 IKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDTSSGGPARAYPVGG 340
Query: 179 ICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMV 358
+CYY SPP+S ++ DP+H IYI FMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMV
Sbjct: 341 LCYYFSPPESFGSVLDDPIHAAIYICFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMV 400
Query: 359 MRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEI 538
MRGHRE SM+HELNRYIPTAAAFGGLCIG LSV+ADFLGAIGSGTGILLAVTIIYQYFEI
Sbjct: 401 MRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEI 460
Query: 539 FVKEQNEMGGSMSTLLF 589
FVKEQ+EM GSM LLF
Sbjct: 461 FVKEQSEM-GSMGALLF 476
>sp|P38377|S61A1_CANFA Protein transport protein Sec61 alpha subunit isoform 1 (Sec61
alpha-1)
Length = 476
Score = 321 bits (822), Expect = 1e-87
Identities = 160/197 (81%), Positives = 179/197 (90%), Gaps = 2/197 (1%)
Frame = +2
Query: 5 IKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG--SRSVPIGG 178
IKLFYTSNIPIILQSALVSNLYVISQMLS +F GNL+++LLGTWSD +G +R+ P+GG
Sbjct: 281 IKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGG 340
Query: 179 ICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMV 358
+C+Y+SPP+S ++ DPVH +YI FMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMV
Sbjct: 341 LCHYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMV 400
Query: 359 MRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEI 538
MRGHRE SM+HELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEI
Sbjct: 401 MRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEI 460
Query: 539 FVKEQNEMGGSMSTLLF 589
FVKEQ+E+ GSM LLF
Sbjct: 461 FVKEQSEV-GSMGALLF 476
>sp|Q7T278|SC61A_HARAN Protein transport protein Sec61 alpha subunit
sp|Q7T277|SC61A_DISMA Protein transport protein Sec61 alpha subunit
Length = 476
Score = 321 bits (822), Expect = 1e-87
Identities = 160/197 (81%), Positives = 176/197 (89%), Gaps = 2/197 (1%)
Frame = +2
Query: 5 IKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG--SRSVPIGG 178
IKLFYTSNIPIILQSALVSNLYVISQMLS +F GN ++NLLGTWSD +G +R+ P+ G
Sbjct: 281 IKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDATSGGPARAYPVAG 340
Query: 179 ICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMV 358
+CYY+SPP+S ++ DPVH IYI FMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMV
Sbjct: 341 LCYYLSPPESFGSVLDDPVHAAIYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMV 400
Query: 359 MRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEI 538
MRGHRE SM+HELNRYIPTAAAFGGLCIG LSV+ADFLGAIGSGTGILLAVTIIYQYFEI
Sbjct: 401 MRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEI 460
Query: 539 FVKEQNEMGGSMSTLLF 589
FVKEQ+EM GSM LLF
Sbjct: 461 FVKEQSEM-GSMGALLF 476
>sp|Q8AY36|SC61A_PAGBO Protein transport protein Sec61 alpha subunit
sp|Q8AY35|SC61A_NOTAN Protein transport protein Sec61 alpha subunit
Length = 476
Score = 321 bits (822), Expect = 1e-87
Identities = 160/197 (81%), Positives = 176/197 (89%), Gaps = 2/197 (1%)
Frame = +2
Query: 5 IKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG--SRSVPIGG 178
IKLFYTSNIPIILQSALVSNLYVISQMLS +F GN ++NLLGTWSD +G +R+ P+ G
Sbjct: 281 IKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDATSGGPARAYPVAG 340
Query: 179 ICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMV 358
+CYY+SPP+S ++ DPVH IYI FMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMV
Sbjct: 341 LCYYLSPPESFGSVLDDPVHAAIYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMV 400
Query: 359 MRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEI 538
MRGHRE SM+HELNRYIPTAAAFGGLCIG LSV+ADFLGAIGSGTGILLAVTIIYQYFEI
Sbjct: 401 MRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEI 460
Query: 539 FVKEQNEMGGSMSTLLF 589
FVKEQ+EM GSM LLF
Sbjct: 461 FVKEQSEM-GSMGALLF 476
>sp|Q9JLR1|S61A2_MOUSE Protein transport protein Sec61 alpha subunit isoform 2 (Sec61
alpha-2)
sp|Q9H9S3|S61A2_HUMAN Protein transport protein Sec61 alpha subunit isoform 2 (Sec61
alpha-2)
Length = 476
Score = 319 bits (818), Expect = 4e-87
Identities = 160/197 (81%), Positives = 176/197 (89%), Gaps = 2/197 (1%)
Frame = +2
Query: 5 IKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG--SRSVPIGG 178
IKLFYTSNIPIILQSALVSNLYVISQMLS +F GN ++NLLG W+D G +RS P+GG
Sbjct: 281 IKLFYTSNIPIILQSALVSNLYVISQMLSVRFSGNFLVNLLGQWADVSGGGPARSYPVGG 340
Query: 179 ICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMV 358
+CYY+SPP+S+ A+F DPVH +YI FMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMV
Sbjct: 341 LCYYLSPPESMGAIFEDPVHVVVYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMV 400
Query: 359 MRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEI 538
MRGHR+ SM+HELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEI
Sbjct: 401 MRGHRDTSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEI 460
Query: 539 FVKEQNEMGGSMSTLLF 589
FVKEQ E+GG M L F
Sbjct: 461 FVKEQAEVGG-MGALFF 476
>sp|Q8AY33|SC61A_BORSA Protein transport protein Sec61 alpha subunit
Length = 476
Score = 319 bits (818), Expect = 4e-87
Identities = 160/197 (81%), Positives = 175/197 (88%), Gaps = 2/197 (1%)
Frame = +2
Query: 5 IKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG--SRSVPIGG 178
IKLFYTSNIPIILQSALVSNLYVISQMLS +F GN I+NLLGTWSD G +R+ P+GG
Sbjct: 281 IKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFIVNLLGTWSDTSTGGPARAYPVGG 340
Query: 179 ICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMV 358
+CY++SPP+S ++ DPVH IYI FMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMV
Sbjct: 341 LCYFLSPPESFGSVLDDPVHAAIYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMV 400
Query: 359 MRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEI 538
MRGHRE SM+HELNRYIPTAAAFGGLCIG LSV+ADFLGAIGSGTGILLAVTIIYQYFEI
Sbjct: 401 MRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEI 460
Query: 539 FVKEQNEMGGSMSTLLF 589
FVKEQ+EM GSM L F
Sbjct: 461 FVKEQSEM-GSMGGLFF 476
>sp|Q90YL4|S61A2_BRARE Protein transport protein Sec61 alpha subunit isoform B
Length = 476
Score = 319 bits (818), Expect = 4e-87
Identities = 158/197 (80%), Positives = 175/197 (88%), Gaps = 2/197 (1%)
Frame = +2
Query: 5 IKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG--SRSVPIGG 178
IKLFYTSNIPIILQSALVSNLYVISQMLS +F GN ++NLLGTWSD G +R+ P+GG
Sbjct: 281 IKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDTSTGGPARAYPVGG 340
Query: 179 ICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMV 358
+CYY+SPP+S + DP+H IYI FMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMV
Sbjct: 341 LCYYLSPPESFGTVLEDPIHAIIYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMV 400
Query: 359 MRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEI 538
MRGHRE SM+HELNRYIPTAAAFGGLCIG LSV+ADFLGAIGSGTGILLAVTIIYQYFEI
Sbjct: 401 MRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEI 460
Query: 539 FVKEQNEMGGSMSTLLF 589
FVKEQ+E+ GS+ LLF
Sbjct: 461 FVKEQSEV-GSVGALLF 476
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,557,417
Number of Sequences: 369166
Number of extensions: 1899899
Number of successful extensions: 6306
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5975
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6254
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6413660220
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)