Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_F16
(745 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P61619|S61A1_HUMAN Protein transport protein Sec61 alpha... 340 2e-93
sp|Q9JLR1|S61A2_MOUSE Protein transport protein Sec61 alpha... 339 4e-93
sp|Q90ZM2|S61A1_BRARE Protein transport protein Sec61 alpha... 339 4e-93
sp|Q8AY32|SC61A_GADOC Protein transport protein Sec61 alpha... 339 4e-93
sp|Q98SN8|S61A2_ONCMY Protein transport protein Sec61 alpha... 339 4e-93
sp|P38377|S61A1_CANFA Protein transport protein Sec61 alpha... 338 7e-93
sp|Q7T278|SC61A_HARAN Protein transport protein Sec61 alpha... 338 7e-93
sp|Q8AY36|SC61A_PAGBO Protein transport protein Sec61 alpha... 338 7e-93
sp|Q8AY33|SC61A_BORSA Protein transport protein Sec61 alpha... 337 2e-92
sp|Q90YL4|S61A2_BRARE Protein transport protein Sec61 alpha... 337 2e-92
>sp|P61619|S61A1_HUMAN Protein transport protein Sec61 alpha subunit isoform 1 (Sec61
alpha-1)
sp|P61621|S61A1_RAT Protein transport protein Sec61 alpha subunit isoform 1 (Sec61
alpha-1)
sp|P61620|S61A1_MOUSE Protein transport protein Sec61 alpha subunit isoform 1 (Sec61
alpha-1)
Length = 476
Score = 340 bits (873), Expect = 2e-93
Identities = 168/207 (81%), Positives = 189/207 (91%), Gaps = 2/207 (0%)
Frame = +1
Query: 1 RYRGQHSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG 180
RYRGQ+++YPIKLFYTSNIPIILQSALVSNLYVISQMLS +F GNL+++LLGTWSD +G
Sbjct: 271 RYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLGTWSDTSSG 330
Query: 181 --SRSVPIGGICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDV 354
+R+ P+GG+CYY+SPP+S ++ DPVH +YI FMLGSCAFFSKTWI+VSGSSAKDV
Sbjct: 331 GPARAYPVGGLCYYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDV 390
Query: 355 AKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 534
AKQLKEQQMVMRGHRE SM+HELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA
Sbjct: 391 AKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 450
Query: 535 VTIIYQYFEIFVKEQNEMGGSMSTLLF 615
VTIIYQYFEIFVKEQ+E+ GSM LLF
Sbjct: 451 VTIIYQYFEIFVKEQSEV-GSMGALLF 476
>sp|Q9JLR1|S61A2_MOUSE Protein transport protein Sec61 alpha subunit isoform 2 (Sec61
alpha-2)
sp|Q9H9S3|S61A2_HUMAN Protein transport protein Sec61 alpha subunit isoform 2 (Sec61
alpha-2)
Length = 476
Score = 339 bits (870), Expect = 4e-93
Identities = 169/207 (81%), Positives = 186/207 (89%), Gaps = 2/207 (0%)
Frame = +1
Query: 1 RYRGQHSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG 180
RYRGQ+SSYPIKLFYTSNIPIILQSALVSNLYVISQMLS +F GN ++NLLG W+D G
Sbjct: 271 RYRGQYSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSVRFSGNFLVNLLGQWADVSGG 330
Query: 181 --SRSVPIGGICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDV 354
+RS P+GG+CYY+SPP+S+ A+F DPVH +YI FMLGSCAFFSKTWI+VSGSSAKDV
Sbjct: 331 GPARSYPVGGLCYYLSPPESMGAIFEDPVHVVVYIIFMLGSCAFFSKTWIEVSGSSAKDV 390
Query: 355 AKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 534
AKQLKEQQMVMRGHR+ SM+HELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA
Sbjct: 391 AKQLKEQQMVMRGHRDTSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 450
Query: 535 VTIIYQYFEIFVKEQNEMGGSMSTLLF 615
VTIIYQYFEIFVKEQ E+GG M L F
Sbjct: 451 VTIIYQYFEIFVKEQAEVGG-MGALFF 476
>sp|Q90ZM2|S61A1_BRARE Protein transport protein Sec61 alpha subunit isoform A
Length = 476
Score = 339 bits (870), Expect = 4e-93
Identities = 167/207 (80%), Positives = 187/207 (90%), Gaps = 2/207 (0%)
Frame = +1
Query: 1 RYRGQHSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG 180
RYRGQ+++YPIKLFYTSNIPIILQSALVSNLYVISQMLS +F GN ++NLLGTWSD +G
Sbjct: 271 RYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDTSSG 330
Query: 181 --SRSVPIGGICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDV 354
+R+ P+GG+CYY+SPP+S ++ DPVH IYI FMLGSCAFFSKTWI+VSGSSAKDV
Sbjct: 331 GPARAYPVGGLCYYLSPPESFGSVLDDPVHAVIYIVFMLGSCAFFSKTWIEVSGSSAKDV 390
Query: 355 AKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 534
AKQLKEQQMVMRGHRE SM+HELNRYIPTAAAFGGLCIG LSV+ADFLGAIGSGTGILLA
Sbjct: 391 AKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLA 450
Query: 535 VTIIYQYFEIFVKEQNEMGGSMSTLLF 615
VTIIYQYFEIFVKEQ+E+ GSM LLF
Sbjct: 451 VTIIYQYFEIFVKEQSEV-GSMGALLF 476
>sp|Q8AY32|SC61A_GADOC Protein transport protein Sec61 alpha subunit
Length = 476
Score = 339 bits (870), Expect = 4e-93
Identities = 168/207 (81%), Positives = 185/207 (89%), Gaps = 2/207 (0%)
Frame = +1
Query: 1 RYRGQHSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG 180
RYRGQ+++YPIKLFYTSNIPIILQSALVSNLYVISQMLS +F GN ++NLLGTWSD G
Sbjct: 271 RYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDTSTG 330
Query: 181 --SRSVPIGGICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDV 354
+R+ P+GG+CYY SPP+S ++ DPVH IYI FMLGSCAFFSKTWI+VSGSSAKDV
Sbjct: 331 GPARAYPVGGLCYYFSPPESFGSVLDDPVHASIYIVFMLGSCAFFSKTWIEVSGSSAKDV 390
Query: 355 AKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 534
AKQLKEQQMVMRGHRE SM+HELNRYIPTAAAFGGLCIG LSV+ADFLGAIGSGTGILLA
Sbjct: 391 AKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLA 450
Query: 535 VTIIYQYFEIFVKEQNEMGGSMSTLLF 615
VTIIYQYFEIFVKEQ+EM GSM LLF
Sbjct: 451 VTIIYQYFEIFVKEQSEM-GSMGALLF 476
>sp|Q98SN8|S61A2_ONCMY Protein transport protein Sec61 alpha subunit isoform B
Length = 476
Score = 339 bits (870), Expect = 4e-93
Identities = 167/207 (80%), Positives = 186/207 (89%), Gaps = 2/207 (0%)
Frame = +1
Query: 1 RYRGQHSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG 180
RYRGQ+++YPIKLFYTSNIPIILQSALVSNLYVISQMLS +F GN ++NLLGTWSD +G
Sbjct: 271 RYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDTSSG 330
Query: 181 --SRSVPIGGICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDV 354
+R+ P+GG+CYY SPP+S ++ DP+H IYI FMLGSCAFFSKTWI+VSGSSAKDV
Sbjct: 331 GPARAYPVGGLCYYFSPPESFGSVLDDPIHAAIYICFMLGSCAFFSKTWIEVSGSSAKDV 390
Query: 355 AKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 534
AKQLKEQQMVMRGHRE SM+HELNRYIPTAAAFGGLCIG LSV+ADFLGAIGSGTGILLA
Sbjct: 391 AKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLA 450
Query: 535 VTIIYQYFEIFVKEQNEMGGSMSTLLF 615
VTIIYQYFEIFVKEQ+EM GSM LLF
Sbjct: 451 VTIIYQYFEIFVKEQSEM-GSMGALLF 476
>sp|P38377|S61A1_CANFA Protein transport protein Sec61 alpha subunit isoform 1 (Sec61
alpha-1)
Length = 476
Score = 338 bits (868), Expect = 7e-93
Identities = 167/207 (80%), Positives = 189/207 (91%), Gaps = 2/207 (0%)
Frame = +1
Query: 1 RYRGQHSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG 180
RYRGQ+++YPIKLFYTSNIPIILQSALVSNLYVISQMLS +F GNL+++LLGTWSD +G
Sbjct: 271 RYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLGTWSDTSSG 330
Query: 181 --SRSVPIGGICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDV 354
+R+ P+GG+C+Y+SPP+S ++ DPVH +YI FMLGSCAFFSKTWI+VSGSSAKDV
Sbjct: 331 GPARAYPVGGLCHYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDV 390
Query: 355 AKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 534
AKQLKEQQMVMRGHRE SM+HELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA
Sbjct: 391 AKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 450
Query: 535 VTIIYQYFEIFVKEQNEMGGSMSTLLF 615
VTIIYQYFEIFVKEQ+E+ GSM LLF
Sbjct: 451 VTIIYQYFEIFVKEQSEV-GSMGALLF 476
>sp|Q7T278|SC61A_HARAN Protein transport protein Sec61 alpha subunit
sp|Q7T277|SC61A_DISMA Protein transport protein Sec61 alpha subunit
Length = 476
Score = 338 bits (868), Expect = 7e-93
Identities = 167/207 (80%), Positives = 186/207 (89%), Gaps = 2/207 (0%)
Frame = +1
Query: 1 RYRGQHSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG 180
RYRGQ+++YPIKLFYTSNIPIILQSALVSNLYVISQMLS +F GN ++NLLGTWSD +G
Sbjct: 271 RYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDATSG 330
Query: 181 --SRSVPIGGICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDV 354
+R+ P+ G+CYY+SPP+S ++ DPVH IYI FMLGSCAFFSKTWI+VSGSSAKDV
Sbjct: 331 GPARAYPVAGLCYYLSPPESFGSVLDDPVHAAIYIVFMLGSCAFFSKTWIEVSGSSAKDV 390
Query: 355 AKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 534
AKQLKEQQMVMRGHRE SM+HELNRYIPTAAAFGGLCIG LSV+ADFLGAIGSGTGILLA
Sbjct: 391 AKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLA 450
Query: 535 VTIIYQYFEIFVKEQNEMGGSMSTLLF 615
VTIIYQYFEIFVKEQ+EM GSM LLF
Sbjct: 451 VTIIYQYFEIFVKEQSEM-GSMGALLF 476
>sp|Q8AY36|SC61A_PAGBO Protein transport protein Sec61 alpha subunit
sp|Q8AY35|SC61A_NOTAN Protein transport protein Sec61 alpha subunit
Length = 476
Score = 338 bits (868), Expect = 7e-93
Identities = 167/207 (80%), Positives = 186/207 (89%), Gaps = 2/207 (0%)
Frame = +1
Query: 1 RYRGQHSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG 180
RYRGQ+++YPIKLFYTSNIPIILQSALVSNLYVISQMLS +F GN ++NLLGTWSD +G
Sbjct: 271 RYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDATSG 330
Query: 181 --SRSVPIGGICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDV 354
+R+ P+ G+CYY+SPP+S ++ DPVH IYI FMLGSCAFFSKTWI+VSGSSAKDV
Sbjct: 331 GPARAYPVAGLCYYLSPPESFGSVLDDPVHAAIYIVFMLGSCAFFSKTWIEVSGSSAKDV 390
Query: 355 AKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 534
AKQLKEQQMVMRGHRE SM+HELNRYIPTAAAFGGLCIG LSV+ADFLGAIGSGTGILLA
Sbjct: 391 AKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLA 450
Query: 535 VTIIYQYFEIFVKEQNEMGGSMSTLLF 615
VTIIYQYFEIFVKEQ+EM GSM LLF
Sbjct: 451 VTIIYQYFEIFVKEQSEM-GSMGALLF 476
>sp|Q8AY33|SC61A_BORSA Protein transport protein Sec61 alpha subunit
Length = 476
Score = 337 bits (864), Expect = 2e-92
Identities = 167/207 (80%), Positives = 185/207 (89%), Gaps = 2/207 (0%)
Frame = +1
Query: 1 RYRGQHSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG 180
RYRGQ+++YPIKLFYTSNIPIILQSALVSNLYVISQMLS +F GN I+NLLGTWSD G
Sbjct: 271 RYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFIVNLLGTWSDTSTG 330
Query: 181 --SRSVPIGGICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDV 354
+R+ P+GG+CY++SPP+S ++ DPVH IYI FMLGSCAFFSKTWI+VSGSSAKDV
Sbjct: 331 GPARAYPVGGLCYFLSPPESFGSVLDDPVHAAIYIVFMLGSCAFFSKTWIEVSGSSAKDV 390
Query: 355 AKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 534
AKQLKEQQMVMRGHRE SM+HELNRYIPTAAAFGGLCIG LSV+ADFLGAIGSGTGILLA
Sbjct: 391 AKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLA 450
Query: 535 VTIIYQYFEIFVKEQNEMGGSMSTLLF 615
VTIIYQYFEIFVKEQ+EM GSM L F
Sbjct: 451 VTIIYQYFEIFVKEQSEM-GSMGGLFF 476
>sp|Q90YL4|S61A2_BRARE Protein transport protein Sec61 alpha subunit isoform B
Length = 476
Score = 337 bits (864), Expect = 2e-92
Identities = 165/207 (79%), Positives = 185/207 (89%), Gaps = 2/207 (0%)
Frame = +1
Query: 1 RYRGQHSSYPIKLFYTSNIPIILQSALVSNLYVISQMLSNKFRGNLIINLLGTWSDGEAG 180
RYRGQ+++YPIKLFYTSNIPIILQSALVSNLYVISQMLS +F GN ++NLLGTWSD G
Sbjct: 271 RYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDTSTG 330
Query: 181 --SRSVPIGGICYYMSPPDSLTAMFHDPVHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDV 354
+R+ P+GG+CYY+SPP+S + DP+H IYI FMLGSCAFFSKTWI+VSGSSAKDV
Sbjct: 331 GPARAYPVGGLCYYLSPPESFGTVLEDPIHAIIYIIFMLGSCAFFSKTWIEVSGSSAKDV 390
Query: 355 AKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLA 534
AKQLKEQQMVMRGHRE SM+HELNRYIPTAAAFGGLCIG LSV+ADFLGAIGSGTGILLA
Sbjct: 391 AKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLA 450
Query: 535 VTIIYQYFEIFVKEQNEMGGSMSTLLF 615
VTIIYQYFEIFVKEQ+E+ GS+ LLF
Sbjct: 451 VTIIYQYFEIFVKEQSEV-GSVGALLF 476
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,376,927
Number of Sequences: 369166
Number of extensions: 1977498
Number of successful extensions: 6837
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6459
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6782
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6728100400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)