Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_N08
(562 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P61619|S61A1_HUMAN Protein transport protein Sec61 alpha... 290 2e-78
sp|Q90ZM2|S61A1_BRARE Protein transport protein Sec61 alpha... 289 4e-78
sp|Q8AY32|SC61A_GADOC Protein transport protein Sec61 alpha... 289 4e-78
sp|Q98SN8|S61A2_ONCMY Protein transport protein Sec61 alpha... 289 4e-78
sp|P38377|S61A1_CANFA Protein transport protein Sec61 alpha... 288 6e-78
sp|Q7T278|SC61A_HARAN Protein transport protein Sec61 alpha... 288 6e-78
sp|Q8AY36|SC61A_PAGBO Protein transport protein Sec61 alpha... 288 6e-78
sp|Q9JLR1|S61A2_MOUSE Protein transport protein Sec61 alpha... 286 2e-77
sp|Q8AY33|SC61A_BORSA Protein transport protein Sec61 alpha... 286 2e-77
sp|Q90YL4|S61A2_BRARE Protein transport protein Sec61 alpha... 286 2e-77
>sp|P61619|S61A1_HUMAN Protein transport protein Sec61 alpha subunit isoform 1 (Sec61
alpha-1)
sp|P61621|S61A1_RAT Protein transport protein Sec61 alpha subunit isoform 1 (Sec61
alpha-1)
sp|P61620|S61A1_MOUSE Protein transport protein Sec61 alpha subunit isoform 1 (Sec61
alpha-1)
Length = 476
Score = 290 bits (742), Expect = 2e-78
Identities = 143/179 (79%), Positives = 161/179 (89%), Gaps = 2/179 (1%)
Frame = +1
Query: 1 SNLYVISQMLSNKFRGNLIINLLGTWSDGEAG--SRSVPIGGICYYMSPPDSLTAMFHDP 174
SNLYVISQMLS +F GNL+++LLGTWSD +G +R+ P+GG+CYY+SPP+S ++ DP
Sbjct: 299 SNLYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDP 358
Query: 175 VHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIP 354
VH +YI FMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMVMRGHRE SM+HELNRYIP
Sbjct: 359 VHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIP 418
Query: 355 TAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQNEMGGSMSTLLF 531
TAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQ+E+ GSM LLF
Sbjct: 419 TAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEV-GSMGALLF 476
>sp|Q90ZM2|S61A1_BRARE Protein transport protein Sec61 alpha subunit isoform A
Length = 476
Score = 289 bits (739), Expect = 4e-78
Identities = 142/179 (79%), Positives = 159/179 (88%), Gaps = 2/179 (1%)
Frame = +1
Query: 1 SNLYVISQMLSNKFRGNLIINLLGTWSDGEAG--SRSVPIGGICYYMSPPDSLTAMFHDP 174
SNLYVISQMLS +F GN ++NLLGTWSD +G +R+ P+GG+CYY+SPP+S ++ DP
Sbjct: 299 SNLYVISQMLSTRFSGNFLVNLLGTWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLDDP 358
Query: 175 VHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIP 354
VH IYI FMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMVMRGHRE SM+HELNRYIP
Sbjct: 359 VHAVIYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIP 418
Query: 355 TAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQNEMGGSMSTLLF 531
TAAAFGGLCIG LSV+ADFLGAIGSGTGILLAVTIIYQYFEIFVKEQ+E+ GSM LLF
Sbjct: 419 TAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEV-GSMGALLF 476
>sp|Q8AY32|SC61A_GADOC Protein transport protein Sec61 alpha subunit
Length = 476
Score = 289 bits (739), Expect = 4e-78
Identities = 143/179 (79%), Positives = 157/179 (87%), Gaps = 2/179 (1%)
Frame = +1
Query: 1 SNLYVISQMLSNKFRGNLIINLLGTWSDGEAG--SRSVPIGGICYYMSPPDSLTAMFHDP 174
SNLYVISQMLS +F GN ++NLLGTWSD G +R+ P+GG+CYY SPP+S ++ DP
Sbjct: 299 SNLYVISQMLSTRFSGNFLVNLLGTWSDTSTGGPARAYPVGGLCYYFSPPESFGSVLDDP 358
Query: 175 VHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIP 354
VH IYI FMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMVMRGHRE SM+HELNRYIP
Sbjct: 359 VHASIYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIP 418
Query: 355 TAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQNEMGGSMSTLLF 531
TAAAFGGLCIG LSV+ADFLGAIGSGTGILLAVTIIYQYFEIFVKEQ+EM GSM LLF
Sbjct: 419 TAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEM-GSMGALLF 476
>sp|Q98SN8|S61A2_ONCMY Protein transport protein Sec61 alpha subunit isoform B
Length = 476
Score = 289 bits (739), Expect = 4e-78
Identities = 142/179 (79%), Positives = 158/179 (88%), Gaps = 2/179 (1%)
Frame = +1
Query: 1 SNLYVISQMLSNKFRGNLIINLLGTWSDGEAG--SRSVPIGGICYYMSPPDSLTAMFHDP 174
SNLYVISQMLS +F GN ++NLLGTWSD +G +R+ P+GG+CYY SPP+S ++ DP
Sbjct: 299 SNLYVISQMLSTRFSGNFLVNLLGTWSDTSSGGPARAYPVGGLCYYFSPPESFGSVLDDP 358
Query: 175 VHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIP 354
+H IYI FMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMVMRGHRE SM+HELNRYIP
Sbjct: 359 IHAAIYICFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIP 418
Query: 355 TAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQNEMGGSMSTLLF 531
TAAAFGGLCIG LSV+ADFLGAIGSGTGILLAVTIIYQYFEIFVKEQ+EM GSM LLF
Sbjct: 419 TAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEM-GSMGALLF 476
>sp|P38377|S61A1_CANFA Protein transport protein Sec61 alpha subunit isoform 1 (Sec61
alpha-1)
Length = 476
Score = 288 bits (737), Expect = 6e-78
Identities = 142/179 (79%), Positives = 161/179 (89%), Gaps = 2/179 (1%)
Frame = +1
Query: 1 SNLYVISQMLSNKFRGNLIINLLGTWSDGEAG--SRSVPIGGICYYMSPPDSLTAMFHDP 174
SNLYVISQMLS +F GNL+++LLGTWSD +G +R+ P+GG+C+Y+SPP+S ++ DP
Sbjct: 299 SNLYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCHYLSPPESFGSVLEDP 358
Query: 175 VHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIP 354
VH +YI FMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMVMRGHRE SM+HELNRYIP
Sbjct: 359 VHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIP 418
Query: 355 TAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQNEMGGSMSTLLF 531
TAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQ+E+ GSM LLF
Sbjct: 419 TAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEV-GSMGALLF 476
>sp|Q7T278|SC61A_HARAN Protein transport protein Sec61 alpha subunit
sp|Q7T277|SC61A_DISMA Protein transport protein Sec61 alpha subunit
Length = 476
Score = 288 bits (737), Expect = 6e-78
Identities = 142/179 (79%), Positives = 158/179 (88%), Gaps = 2/179 (1%)
Frame = +1
Query: 1 SNLYVISQMLSNKFRGNLIINLLGTWSDGEAG--SRSVPIGGICYYMSPPDSLTAMFHDP 174
SNLYVISQMLS +F GN ++NLLGTWSD +G +R+ P+ G+CYY+SPP+S ++ DP
Sbjct: 299 SNLYVISQMLSTRFSGNFLVNLLGTWSDATSGGPARAYPVAGLCYYLSPPESFGSVLDDP 358
Query: 175 VHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIP 354
VH IYI FMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMVMRGHRE SM+HELNRYIP
Sbjct: 359 VHAAIYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIP 418
Query: 355 TAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQNEMGGSMSTLLF 531
TAAAFGGLCIG LSV+ADFLGAIGSGTGILLAVTIIYQYFEIFVKEQ+EM GSM LLF
Sbjct: 419 TAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEM-GSMGALLF 476
>sp|Q8AY36|SC61A_PAGBO Protein transport protein Sec61 alpha subunit
sp|Q8AY35|SC61A_NOTAN Protein transport protein Sec61 alpha subunit
Length = 476
Score = 288 bits (737), Expect = 6e-78
Identities = 142/179 (79%), Positives = 158/179 (88%), Gaps = 2/179 (1%)
Frame = +1
Query: 1 SNLYVISQMLSNKFRGNLIINLLGTWSDGEAG--SRSVPIGGICYYMSPPDSLTAMFHDP 174
SNLYVISQMLS +F GN ++NLLGTWSD +G +R+ P+ G+CYY+SPP+S ++ DP
Sbjct: 299 SNLYVISQMLSTRFSGNFLVNLLGTWSDATSGGPARAYPVAGLCYYLSPPESFGSVLDDP 358
Query: 175 VHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIP 354
VH IYI FMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMVMRGHRE SM+HELNRYIP
Sbjct: 359 VHAAIYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIP 418
Query: 355 TAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQNEMGGSMSTLLF 531
TAAAFGGLCIG LSV+ADFLGAIGSGTGILLAVTIIYQYFEIFVKEQ+EM GSM LLF
Sbjct: 419 TAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEM-GSMGALLF 476
>sp|Q9JLR1|S61A2_MOUSE Protein transport protein Sec61 alpha subunit isoform 2 (Sec61
alpha-2)
sp|Q9H9S3|S61A2_HUMAN Protein transport protein Sec61 alpha subunit isoform 2 (Sec61
alpha-2)
Length = 476
Score = 286 bits (733), Expect = 2e-77
Identities = 142/179 (79%), Positives = 158/179 (88%), Gaps = 2/179 (1%)
Frame = +1
Query: 1 SNLYVISQMLSNKFRGNLIINLLGTWSDGEAG--SRSVPIGGICYYMSPPDSLTAMFHDP 174
SNLYVISQMLS +F GN ++NLLG W+D G +RS P+GG+CYY+SPP+S+ A+F DP
Sbjct: 299 SNLYVISQMLSVRFSGNFLVNLLGQWADVSGGGPARSYPVGGLCYYLSPPESMGAIFEDP 358
Query: 175 VHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIP 354
VH +YI FMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMVMRGHR+ SM+HELNRYIP
Sbjct: 359 VHVVVYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRDTSMVHELNRYIP 418
Query: 355 TAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQNEMGGSMSTLLF 531
TAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQ E+GG M L F
Sbjct: 419 TAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQAEVGG-MGALFF 476
>sp|Q8AY33|SC61A_BORSA Protein transport protein Sec61 alpha subunit
Length = 476
Score = 286 bits (733), Expect = 2e-77
Identities = 142/179 (79%), Positives = 157/179 (87%), Gaps = 2/179 (1%)
Frame = +1
Query: 1 SNLYVISQMLSNKFRGNLIINLLGTWSDGEAG--SRSVPIGGICYYMSPPDSLTAMFHDP 174
SNLYVISQMLS +F GN I+NLLGTWSD G +R+ P+GG+CY++SPP+S ++ DP
Sbjct: 299 SNLYVISQMLSTRFSGNFIVNLLGTWSDTSTGGPARAYPVGGLCYFLSPPESFGSVLDDP 358
Query: 175 VHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIP 354
VH IYI FMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMVMRGHRE SM+HELNRYIP
Sbjct: 359 VHAAIYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIP 418
Query: 355 TAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQNEMGGSMSTLLF 531
TAAAFGGLCIG LSV+ADFLGAIGSGTGILLAVTIIYQYFEIFVKEQ+EM GSM L F
Sbjct: 419 TAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEM-GSMGGLFF 476
>sp|Q90YL4|S61A2_BRARE Protein transport protein Sec61 alpha subunit isoform B
Length = 476
Score = 286 bits (733), Expect = 2e-77
Identities = 140/179 (78%), Positives = 157/179 (87%), Gaps = 2/179 (1%)
Frame = +1
Query: 1 SNLYVISQMLSNKFRGNLIINLLGTWSDGEAG--SRSVPIGGICYYMSPPDSLTAMFHDP 174
SNLYVISQMLS +F GN ++NLLGTWSD G +R+ P+GG+CYY+SPP+S + DP
Sbjct: 299 SNLYVISQMLSTRFSGNFLVNLLGTWSDTSTGGPARAYPVGGLCYYLSPPESFGTVLEDP 358
Query: 175 VHGFIYIAFMLGSCAFFSKTWIDVSGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIP 354
+H IYI FMLGSCAFFSKTWI+VSGSSAKDVAKQLKEQQMVMRGHRE SM+HELNRYIP
Sbjct: 359 IHAIIYIIFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIP 418
Query: 355 TAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQNEMGGSMSTLLF 531
TAAAFGGLCIG LSV+ADFLGAIGSGTGILLAVTIIYQYFEIFVKEQ+E+ GS+ LLF
Sbjct: 419 TAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEV-GSVGALLF 476
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,870,125
Number of Sequences: 369166
Number of extensions: 1533799
Number of successful extensions: 5280
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5023
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5240
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4029688280
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)