DrC_00391
- Cluster detail
- GO Category :
- Consensus Sequence :
BLASTX 2.2.13 [Nov-27-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00391 (1538 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9UEW8|STK39_HUMAN STE20/SPS1-related proline-alanine-ri... 324 5e-88 sp|Q9Z1W9|STK39_MOUSE STE20/SPS1-related proline-alanine-ri... 316 1e-85 sp|O88506|STK39_RAT STE20/SPS1-related proline-alanine-rich... 314 5e-85 sp|Q5R495|OXSR1_PONPY Serine/threonine-protein kinase OSR1 ... 286 9e-77 sp|Q6P9R2|OXSR1_MOUSE Serine/threonine-protein kinase OSR1 ... 286 1e-76 sp|O95747|OXSR1_HUMAN Serine/threonine-protein kinase OSR1 ... 285 2e-76 sp|Q863I2|OXSR1_PIG Serine/threonine-protein kinase OSR1 (O... 285 2e-76 sp|Q9Y6E0|STK24_HUMAN Serine/threonine-protein kinase 24 (S... 195 3e-49 sp|Q99KH8|STK24_MOUSE Serine/threonine-protein kinase 24 193 1e-48 sp|Q99JT2|MST4_MOUSE Serine/threonine-protein kinase MST4 (... 191 4e-48
>sp|Q9UEW8|STK39_HUMAN STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20 related kinase) (Serine/threonine-protein kinase 39) (DCHT) Length = 547 Score = 324 bits (830), Expect = 5e-88 Identities = 194/478 (40%), Positives = 271/478 (56%), Gaps = 42/478 (8%) Frame = +1 Query: 1 TSTVYEAACPILNDRKCAMKIINLEKCSSSTLLDEIKKEIRGMRNLKNENIVTYYASFVA 180 T+ V A C +R A+K INLEKC +S +DE+ KEI+ M + N+VTYY SFV Sbjct: 76 TAVVQAALCKPRQER-VAIKRINLEKCQTS--MDELLKEIQAMSQCSHPNVVTYYTSFVV 132 Query: 181 GTELCILMDLCQKGSLLDIIKATQNKRDISSGVLDENTIATIMKDVLKGLSYIHENGLVH 360 EL ++M L GS+LDIIK N+ + +GVL+E IATI+K+VL+GL Y+H NG +H Sbjct: 133 KDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIH 192 Query: 361 RDLKCGNLLVKDDAVIQIADFGVAGFLAARPMEATGMSLDDKRFTFVGTPCWMAPEVMQQ 540 RDLK GN+L+ +D +QIADFGV+ FLA ++ + R TFVGTPCWMAPEVM+Q Sbjct: 193 RDLKAGNILLGEDGSVQIADFGVSAFLAT----GGDVTRNKVRKTFVGTPCWMAPEVMEQ 248 Query: 541 VKGYNQKADIWSIGITSIEMATGQAPYAKYTPMKVLMLTLQNEPPDIDTAATSSNQYTNY 720 V+GY+ KAD+WS GIT+IE+ATG APY KY PMKVLMLTLQN+PP ++T Y Sbjct: 249 VRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKY 308 Query: 721 GHKYRKFTKVCLCKDPTQRPSAKELLQSPFIKSKSRDRELLSKILLNCDIPPAPDRKVR- 897 G +RK +CL KDP++RP+A ELL+ F + L+ K+L +KVR Sbjct: 309 GKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKVRR 368 Query: 898 -----------------------DEKQEKNPKDFSGEWNFDIKGKN-------------- 966 DEK E+ FS E + +K +N Sbjct: 369 VPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSASTIPEQI 428 Query: 967 --XXXXXXEDPPGPKTKTSTAENVFYRITLRKRNPKQNNELQDISFIYVLGKDSVDVLAR 1140 + PP A + + LR RN ++ EL DI F + G+D+ D +++ Sbjct: 429 QSLSVHDSQGPPNANEDYREASSCAVNLVLRLRNSRK--ELNDIRFEFTPGRDTADGVSQ 486 Query: 1141 ELVEADLLDGCDLLLVAHNLSELVAEP-TMRERVFALNSP-PASGVINEADLNGYAKV 1308 EL A L+DG D+++VA NL ++V +P ++ F L S S + +E L G+A++ Sbjct: 487 ELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFAQL 544
>sp|Q9Z1W9|STK39_MOUSE STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20 related kinase) (Serine/threonine-protein kinase 39) Length = 556 Score = 316 bits (810), Expect = 1e-85 Identities = 196/477 (41%), Positives = 272/477 (57%), Gaps = 41/477 (8%) Frame = +1 Query: 1 TSTVYEAACPILNDRKCAMKIINLEKCSSSTLLDEIKKEIRGMRNLKNENIVTYYASFVA 180 T+ V A C +R A+K INLEKC +S +DE+ KEI+ M + N+VTYY SFV Sbjct: 86 TAVVQAALCKPRQER-VAIKRINLEKCQTS--MDELLKEIQAMSQCSHPNVVTYYTSFVV 142 Query: 181 GTELCILMDLCQKGSLLDIIKATQNKRDISSGVLDENTIATIMKDVLKGLSYIHENGLVH 360 EL ++M L GS+LDIIK N+ + +GVL+E IATI+K+VL+GL Y+H NG +H Sbjct: 143 KDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIH 202 Query: 361 RDLKCGNLLVKDDAVIQIADFGVAGFLAARPMEATGMSLDDKRFTFVGTPCWMAPEVMQQ 540 RDLK GN+L+ +D +QIADFGV+ FLA ++ + R TFVGTPCWMAPEVM+Q Sbjct: 203 RDLKAGNILLGEDGSVQIADFGVSAFLAT----GGDVTRNKVRKTFVGTPCWMAPEVMEQ 258 Query: 541 VKGYNQKADIWSIGITSIEMATGQAPYAKYTPMKVLMLTLQNEPPDIDTAATSSNQYTNY 720 V+GY+ KAD+WS GIT+IE+ATG APY KY PMKVLMLTLQN+PP ++T Y Sbjct: 259 VRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKY 318 Query: 721 GHKYRKFTKVCLCKDPTQRPSAKELLQSPFIKSKSRDRELLSKILLNCDIPPAPDRKVR- 897 G +RK +CL KDP++RP+A ELL+ F + L+ K+L +KVR Sbjct: 319 GKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKVRR 378 Query: 898 -----------------------DEKQEKNPKDFSGEWNFDIKGKN-----XXXXXXEDP 993 DEK E+ S E + +K +N E Sbjct: 379 VPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAASQEKSRRVKEENSEISVNAGGIPEQI 438 Query: 994 PGPKTKTSTAE---NVFYR-------ITLRKRNPKQNNELQDISFIYVLGKDSVDVLARE 1143 S A+ N YR + LR RN ++ EL DI F + G+D+ D +++E Sbjct: 439 QSLSVHDSQAQPNANEDYREGPCAVNLVLRLRNSRK--ELNDIRFEFTPGRDTADGVSQE 496 Query: 1144 LVEADLLDGCDLLLVAHNLSELVAEP-TMRERVFALNSP-PASGVINEADLNGYAKV 1308 L A L+DG D+++VA NL ++V +P ++ F L S S + +E L G+A++ Sbjct: 497 LFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFAQL 553
>sp|O88506|STK39_RAT STE20/SPS1-related proline-alanine-rich protein kinase (Ste-20 related kinase) (Serine/threonine-protein kinase 39) (Pancreatic serine/threonine-protein kinase) (PS/TK) (PSTK1) Length = 553 Score = 314 bits (804), Expect = 5e-85 Identities = 192/477 (40%), Positives = 272/477 (57%), Gaps = 41/477 (8%) Frame = +1 Query: 1 TSTVYEAACPILNDRKCAMKIINLEKCSSSTLLDEIKKEIRGMRNLKNENIVTYYASFVA 180 T+ V A C +R A+K INLEKC +S +DE+ KEI+ M + N+VTYY SFV Sbjct: 83 TAVVQAALCKPRQER-VAIKRINLEKCQTS--MDELLKEIQAMSQCSHPNVVTYYTSFVV 139 Query: 181 GTELCILMDLCQKGSLLDIIKATQNKRDISSGVLDENTIATIMKDVLKGLSYIHENGLVH 360 EL ++M L GS+LDIIK N+ + +GVL+E IATI+K+VL+GL Y+H NG +H Sbjct: 140 KDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIH 199 Query: 361 RDLKCGNLLVKDDAVIQIADFGVAGFLAARPMEATGMSLDDKRFTFVGTPCWMAPEVMQQ 540 RDLK GN+L+ +D +QIADFGV+ FLA ++ + R TFVGTPCWMAPEVM+Q Sbjct: 200 RDLKAGNILLGEDGSVQIADFGVSAFLAT----GGDVTRNKVRKTFVGTPCWMAPEVMEQ 255 Query: 541 VKGYNQKADIWSIGITSIEMATGQAPYAKYTPMKVLMLTLQNEPPDIDTAATSSNQYTNY 720 V+GY+ KAD+WS GIT+IE+ATG APY KY PMKVLMLTLQN+PP ++T Y Sbjct: 256 VRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKY 315 Query: 721 GHKYRKFTKVCLCKDPTQRPSAKELLQSPFIKSKSRDRELLSKILLNCDIPPAPDRKVR- 897 G +RK +CL KDP++RP+A ELL+ F + L+ K+L +KVR Sbjct: 316 GKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKVRR 375 Query: 898 -----------------------DEKQEKNPKDFSGEWNFDIKGKNXXXXXXEDPPGPKT 1008 DEK E+ S E + +K +N + Sbjct: 376 VPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAASQEKSRRVKEENPEISVNAGGIPEQI 435 Query: 1009 KTSTAE--------NVFYR-------ITLRKRNPKQNNELQDISFIYVLGKDSVDVLARE 1143 ++ + N YR + LR RN ++ EL DI F + G+D+ D +++E Sbjct: 436 QSLSVHDSQGQPNANEDYREGPCAVNLVLRLRNSRK--ELNDIRFEFTPGRDTADGVSQE 493 Query: 1144 LVEADLLDGCDLLLVAHNLSELVAEP-TMRERVFALNSP-PASGVINEADLNGYAKV 1308 L A L+DG D+++VA NL ++V +P ++ F L S + + +E L G+A++ Sbjct: 494 LFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGAEIPDEVKLIGFAQL 550
>sp|Q5R495|OXSR1_PONPY Serine/threonine-protein kinase OSR1 (Oxidative stress-responsive 1 protein) Length = 527 Score = 286 bits (733), Expect = 9e-77 Identities = 157/325 (48%), Positives = 211/325 (64%), Gaps = 9/325 (2%) Frame = +1 Query: 4 STVYEAACPILNDRKCAMKIINLEKCSSSTLLDEIKKEIRGMRNLKNENIVTYYASFVAG 183 + V +AA K A+K INLEKC +S +DE+ KEI+ M + NIV+YY SFV Sbjct: 28 TAVVQAAYCAPKKEKVAIKRINLEKCQTS--MDELLKEIQAMSQCHHPNIVSYYTSFVVK 85 Query: 184 TELCILMDLCQKGSLLDIIKATQNKRDISSGVLDENTIATIMKDVLKGLSYIHENGLVHR 363 EL ++M L GS+LDIIK K + SGVLDE+TIATI+++VL+GL Y+H+NG +HR Sbjct: 86 DELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHR 145 Query: 364 DLKCGNLLVKDDAVIQIADFGVAGFLAARPMEATGMSLDDKRFTFVGTPCWMAPEVMQQV 543 D+K GN+L+ +D +QIADFGV+ FLA ++ + R TFVGTPCWMAPEVM+QV Sbjct: 146 DVKAGNILLGEDGSVQIADFGVSAFLAT----GGDITRNKVRKTFVGTPCWMAPEVMEQV 201 Query: 544 KGYNQKADIWSIGITSIEMATGQAPYAKYTPMKVLMLTLQNEPPDIDTAATSSNQYTNYG 723 +GY+ KADIWS GIT+IE+ATG APY KY PMKVLMLTLQN+PP ++T YG Sbjct: 202 RGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYG 261 Query: 724 HKYRKFTKVCLCKDPTQRPSAKELLQSPFIKSKSRDRELLSKILLNCDIPPAPDRKVRDE 903 +RK +CL KDP +RP+A ELL+ F + K++++E L + +L AP R + Sbjct: 262 KSFRKMISLCLQKDPEKRPTAAELLRHKFFQ-KAKNKEFLQEKILQ----RAPTISERAK 316 Query: 904 KQEKNP---------KDFSGEWNFD 951 K + P +D EW+ D Sbjct: 317 KVRRVPGSSGRLHKTEDGGWEWSDD 341
Score = 55.5 bits (132), Expect = 4e-07
Identities = 35/91 (38%), Positives = 57/91 (62%), Gaps = 2/91 (2%)
Frame = +1
Query: 1042 ITLRKRNPKQNNELQDISFIYVLGKDSVDVLARELVEADLLDGCDLLLVAHNLSELVAEP 1221
+ LR RN K+ EL DI F + G+D+ + +++EL+ A L+DG DL++VA NL ++V EP
Sbjct: 436 LVLRLRNSKK--ELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLVIVAANLQKIVEEP 493
Query: 1222 -TMRERVFALNS-PPASGVINEADLNGYAKV 1308
+ R F L S S + ++ L G+A++
Sbjct: 494 QSNRSVTFKLASGVEGSDIPDDGKLIGFAQL 524
>sp|Q6P9R2|OXSR1_MOUSE Serine/threonine-protein kinase OSR1 (Oxidative stress-responsive 1 protein) Length = 527 Score = 286 bits (731), Expect = 1e-76 Identities = 158/326 (48%), Positives = 211/326 (64%), Gaps = 9/326 (2%) Frame = +1 Query: 1 TSTVYEAACPILNDRKCAMKIINLEKCSSSTLLDEIKKEIRGMRNLKNENIVTYYASFVA 180 T+ V A C +R A+K INLEKC +S +DE+ KEI+ M + NIV+YY SFV Sbjct: 28 TAVVQAAYCAPKKER-VAIKRINLEKCQTS--MDELLKEIQAMSQCHHPNIVSYYTSFVV 84 Query: 181 GTELCILMDLCQKGSLLDIIKATQNKRDISSGVLDENTIATIMKDVLKGLSYIHENGLVH 360 EL ++M L GS+LDIIK K + SGVLDE TIATI+++VL+GL Y+H+NG +H Sbjct: 85 KDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEPTIATILREVLEGLEYLHKNGQIH 144 Query: 361 RDLKCGNLLVKDDAVIQIADFGVAGFLAARPMEATGMSLDDKRFTFVGTPCWMAPEVMQQ 540 RD+K GN+L+ +D +QIADFGV+ FLA ++ + R TFVGTPCWMAPEVM+Q Sbjct: 145 RDVKAGNILLGEDGSVQIADFGVSAFLAT----GGDITRNKVRKTFVGTPCWMAPEVMEQ 200 Query: 541 VKGYNQKADIWSIGITSIEMATGQAPYAKYTPMKVLMLTLQNEPPDIDTAATSSNQYTNY 720 V+GY+ KADIWS GIT+IE+ATG APY KY PMKVLMLTLQN+PP ++T Y Sbjct: 201 VRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKY 260 Query: 721 GHKYRKFTKVCLCKDPTQRPSAKELLQSPFIKSKSRDRELLSKILLNCDIPPAPDRKVRD 900 G +RK +CL KDP +RP+A ELL+ F + K++++E L + +L AP R Sbjct: 261 GKSFRKMISLCLQKDPEKRPTAAELLRHKFFQ-KAKNKEFLQEKILQ----RAPTISERS 315 Query: 901 EKQEKNP---------KDFSGEWNFD 951 +K + P +D EW+ D Sbjct: 316 KKVRRVPGSSGRLHKTEDGGWEWSDD 341
Score = 55.8 bits (133), Expect = 3e-07
Identities = 40/117 (34%), Positives = 65/117 (55%), Gaps = 11/117 (9%)
Frame = +1
Query: 991 PPGPKTKTSTAENVFYR---------ITLRKRNPKQNNELQDISFIYVLGKDSVDVLARE 1143
PP K + A++ R + LR RN K+ EL DI F + G+D+ + +++E
Sbjct: 410 PPAEPAKPAQAQSSGERSQETKIPISLVLRLRNSKK--ELNDIRFEFTPGRDTAEGVSQE 467
Query: 1144 LVEADLLDGCDLLLVAHNLSELVAEP-TMRERVFALNS-PPASGVINEADLNGYAKV 1308
L+ A L+DG DL++VA NL ++V EP + R F L S S + ++ L G+A++
Sbjct: 468 LISAGLVDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQL 524
>sp|O95747|OXSR1_HUMAN Serine/threonine-protein kinase OSR1 (Oxidative stress-responsive 1 protein) Length = 527 Score = 285 bits (730), Expect = 2e-76 Identities = 157/325 (48%), Positives = 210/325 (64%), Gaps = 9/325 (2%) Frame = +1 Query: 4 STVYEAACPILNDRKCAMKIINLEKCSSSTLLDEIKKEIRGMRNLKNENIVTYYASFVAG 183 + V +AA K A+K INLEKC +S +DE+ KEI+ M + NIV+YY SFV Sbjct: 28 TAVVQAAYCAPKKEKVAIKRINLEKCQTS--MDELLKEIQAMSQCHHPNIVSYYTSFVVK 85 Query: 184 TELCILMDLCQKGSLLDIIKATQNKRDISSGVLDENTIATIMKDVLKGLSYIHENGLVHR 363 EL ++M L GS+LDIIK K + SGVLDE+TIATI+++VL+GL Y+H+NG +HR Sbjct: 86 DELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHR 145 Query: 364 DLKCGNLLVKDDAVIQIADFGVAGFLAARPMEATGMSLDDKRFTFVGTPCWMAPEVMQQV 543 D+K GN+L+ +D +QIADFGV+ FLA ++ + R TFVGTPCWMAPEVM+QV Sbjct: 146 DVKAGNILLGEDGSVQIADFGVSAFLAT----GGDITRNKVRKTFVGTPCWMAPEVMEQV 201 Query: 544 KGYNQKADIWSIGITSIEMATGQAPYAKYTPMKVLMLTLQNEPPDIDTAATSSNQYTNYG 723 +GY+ KADIWS GIT+IE+ATG APY KY PMKVLMLTLQN+PP ++T YG Sbjct: 202 RGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYG 261 Query: 724 HKYRKFTKVCLCKDPTQRPSAKELLQSPFIKSKSRDRELLSKILLNCDIPPAPDRKVRDE 903 +RK +CL KDP +RP+A ELL+ F + K++++E L + L AP R + Sbjct: 262 KSFRKMISLCLQKDPEKRPTAAELLRHKFFQ-KAKNKEFLQEKTLQ----RAPTISERAK 316 Query: 904 KQEKNP---------KDFSGEWNFD 951 K + P +D EW+ D Sbjct: 317 KVRRVPGSSGRLHKTEDGGWEWSDD 341
Score = 55.5 bits (132), Expect = 4e-07
Identities = 35/91 (38%), Positives = 57/91 (62%), Gaps = 2/91 (2%)
Frame = +1
Query: 1042 ITLRKRNPKQNNELQDISFIYVLGKDSVDVLARELVEADLLDGCDLLLVAHNLSELVAEP 1221
+ LR RN K+ EL DI F + G+D+ + +++EL+ A L+DG DL++VA NL ++V EP
Sbjct: 436 LVLRLRNSKK--ELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLVIVAANLQKIVEEP 493
Query: 1222 -TMRERVFALNS-PPASGVINEADLNGYAKV 1308
+ R F L S S + ++ L G+A++
Sbjct: 494 QSNRSVTFKLASGVEGSDIPDDGKLIGFAQL 524
>sp|Q863I2|OXSR1_PIG Serine/threonine-protein kinase OSR1 (Oxidative stress-responsive 1 protein) Length = 529 Score = 285 bits (730), Expect = 2e-76 Identities = 155/320 (48%), Positives = 202/320 (63%), Gaps = 4/320 (1%) Frame = +1 Query: 4 STVYEAACPILNDRKCAMKIINLEKCSSSTLLDEIKKEIRGMRNLKNENIVTYYASFVAG 183 + V +AA K A+K INLEKC +S +DE+ KEI+ M + NIV+YY SFV Sbjct: 28 TAVVQAAYCTPKKEKVAIKRINLEKCQTS--MDELLKEIQAMSQCHHPNIVSYYTSFVVK 85 Query: 184 TELCILMDLCQKGSLLDIIKATQNKRDISSGVLDENTIATIMKDVLKGLSYIHENGLVHR 363 EL ++M L GS+LDIIK K + SGVLDE TIATI+++VL+GL Y+H+NG +HR Sbjct: 86 DELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEATIATILREVLEGLEYLHKNGQIHR 145 Query: 364 DLKCGNLLVKDDAVIQIADFGVAGFLAARPMEATGMSLDDKRFTFVGTPCWMAPEVMQQV 543 D+K GN+L+ +D +QIADFGV+ FLA ++ + R TFVGTPCWMAPEVM+QV Sbjct: 146 DVKAGNILLGEDGSVQIADFGVSAFLAT----GGDITRNKVRKTFVGTPCWMAPEVMEQV 201 Query: 544 KGYNQKADIWSIGITSIEMATGQAPYAKYTPMKVLMLTLQNEPPDIDTAATSSNQYTNYG 723 +GY+ KADIWS GIT+IE+ATG APY KY PMKVLMLTLQN+PP ++T YG Sbjct: 202 RGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYG 261 Query: 724 HKYRKFTKVCLCKDPTQRPSAKELLQSPFIKSKSRDRELLSKILLNCDIPPAPDRKVR-- 897 +RK +CL KDP +RP+A ELL+ F + L KIL +KVR Sbjct: 262 KSFRKMISLCLQKDPEKRPTAAELLRHKFFQKAKNKEYLQEKILQRAPTISERAKKVRRV 321 Query: 898 --DEKQEKNPKDFSGEWNFD 951 + +D EW+ D Sbjct: 322 PGSSGRLHKTEDGGWEWSDD 341
Score = 55.8 bits (133), Expect = 3e-07
Identities = 35/91 (38%), Positives = 58/91 (63%), Gaps = 2/91 (2%)
Frame = +1
Query: 1042 ITLRKRNPKQNNELQDISFIYVLGKDSVDVLARELVEADLLDGCDLLLVAHNLSELVAEP 1221
+ LR RN K+ EL DI F + G+D+ + +++EL+ A L+DG DL++VA NL ++V EP
Sbjct: 438 LVLRLRNSKK--ELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLVIVAANLQKIVEEP 495
Query: 1222 -TMRERVFALNS-PPASGVINEADLNGYAKV 1308
+ R F L S S + +++ L G+A++
Sbjct: 496 QSNRSVTFKLASGVEGSDIPDDSKLIGFAQL 526
>sp|Q9Y6E0|STK24_HUMAN Serine/threonine-protein kinase 24 (STE20-like kinase MST3) (MST-3) (Mammalian STE20-like protein kinase 3) Length = 443 Score = 195 bits (495), Expect = 3e-49 Identities = 114/314 (36%), Positives = 179/314 (57%), Gaps = 9/314 (2%) Frame = +1 Query: 52 AMKIINLEKCSSSTLLDEIKKEIRGMRNLKNENIVTYYASFVAGTELCILMDLCQKGSLL 231 A+KII+LE+ +++I++EI + + + YY S++ T+L I+M+ GS L Sbjct: 63 AIKIIDLEEAEDE--IEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSAL 120 Query: 232 DIIKATQNKRDISSGVLDENTIATIMKDVLKGLSYIHENGLVHRDLKCGNLLVKDDAVIQ 411 D+++ G LDE IATI++++LKGL Y+H +HRD+K N+L+ + ++ Sbjct: 121 DLLEP---------GPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVK 171 Query: 412 IADFGVAGFLAARPMEATGMSLDDKRFTFVGTPCWMAPEVMQQVKGYNQKADIWSIGITS 591 +ADFGVAG L + KR TFVGTP WMAPEV++Q Y+ KADIWS+GIT+ Sbjct: 172 LADFGVAGQLTDTQI---------KRNTFVGTPFWMAPEVIKQ-SAYDSKADIWSLGITA 221 Query: 592 IEMATGQAPYAKYTPMKVLMLTLQNEPPDIDTAATSSNQYTNYGHKYRKFTKVCLCKDPT 771 IE+A G+ P+++ PMKVL L +N PP ++ NY ++F + CL K+P+ Sbjct: 222 IELARGEPPHSELHPMKVLFLIPKNNPPTLE---------GNYSKPLKEFVEACLNKEPS 272 Query: 772 QRPSAKELLQSPFIKSKSRDRELLSKIL---------LNCDIPPAPDRKVRDEKQEKNPK 924 RP+AKELL+ FI ++ L++++ + D + D + Q Sbjct: 273 FRPTAKELLKHKFILRNAKKTSYLTELIDRYKRWKAEQSHDDSSSEDSDAETDGQASGGS 332 Query: 925 DFSGEWNFDIKGKN 966 D SG+W F I+ K+ Sbjct: 333 D-SGDWIFTIREKD 345
>sp|Q99KH8|STK24_MOUSE Serine/threonine-protein kinase 24 Length = 431 Score = 193 bits (491), Expect = 1e-48 Identities = 114/314 (36%), Positives = 180/314 (57%), Gaps = 9/314 (2%) Frame = +1 Query: 52 AMKIINLEKCSSSTLLDEIKKEIRGMRNLKNENIVTYYASFVAGTELCILMDLCQKGSLL 231 A+KII+LE+ +++I++EI + + + YY S++ T+L I+M+ GS L Sbjct: 51 AIKIIDLEEAEDE--IEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSAL 108 Query: 232 DIIKATQNKRDISSGVLDENTIATIMKDVLKGLSYIHENGLVHRDLKCGNLLVKDDAVIQ 411 D+++ G LDE IATI++++LKGL Y+H +HRD+K N+L+ + ++ Sbjct: 109 DLLEP---------GPLDEIQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVK 159 Query: 412 IADFGVAGFLAARPMEATGMSLDDKRFTFVGTPCWMAPEVMQQVKGYNQKADIWSIGITS 591 +ADFGVAG L + KR TFVGTP WMAPEV++Q Y+ KADIWS+GIT+ Sbjct: 160 LADFGVAGQLTDTQI---------KRNTFVGTPFWMAPEVIKQ-SAYDSKADIWSLGITA 209 Query: 592 IEMATGQAPYAKYTPMKVLMLTLQNEPPDIDTAATSSNQYTNYGHKYRKFTKVCLCKDPT 771 IE+A G+ P+++ PMKVL L +N PP ++ NY ++F + CL K+P+ Sbjct: 210 IELAKGEPPHSELHPMKVLFLIPKNNPPTLE---------GNYSKPLKEFVEACLNKEPS 260 Query: 772 QRPSAKELLQSPFIKSKSRDRELLSKIL---------LNCDIPPAPDRKVRDEKQEKNPK 924 RP+AKELL+ FI ++ L++++ + + + D V + Q Sbjct: 261 FRPTAKELLKHKFIIRNAKKTSYLTELIDRYKRWKAEQSHEDSSSEDSDVETDGQASGGS 320 Query: 925 DFSGEWNFDIKGKN 966 D SG+W F I+ K+ Sbjct: 321 D-SGDWIFTIREKD 333
>sp|Q99JT2|MST4_MOUSE Serine/threonine-protein kinase MST4 (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) Length = 416 Score = 191 bits (486), Expect = 4e-48 Identities = 123/349 (35%), Positives = 190/349 (54%), Gaps = 2/349 (0%) Frame = +1 Query: 52 AMKIINLEKCSSSTLLDEIKKEIRGMRNLKNENIVTYYASFVAGTELCILMDLCQKGSLL 231 A+KII+LE+ +++I++EI + + + YY S++ G++L I+M+ GS L Sbjct: 51 AIKIIDLEEAEDE--IEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSAL 108 Query: 232 DIIKATQNKRDISSGVLDENTIATIMKDVLKGLSYIHENGLVHRDLKCGNLLVKDDAVIQ 411 D+++A G DE IAT++K++LKGL Y+H +HRD+K N+L+ + ++ Sbjct: 109 DLLRA---------GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVK 159 Query: 412 IADFGVAGFLAARPMEATGMSLDDKRFTFVGTPCWMAPEVMQQVKGYNQKADIWSIGITS 591 +ADFGVAG L + KR TFVGTP WMAPEV+QQ Y+ KADIWS+GIT+ Sbjct: 160 LADFGVAGQLTDTQI---------KRNTFVGTPFWMAPEVIQQ-SAYDSKADIWSLGITA 209 Query: 592 IEMATGQAPYAKYTPMKVLMLTLQNEPPDIDTAATSSNQYTNYGHKYRKFTKVCLCKDPT 771 IE+A G+ P + PM+VL L +N PP + T S +++F CL KDP+ Sbjct: 210 IELAKGEPPNSDMHPMRVLFLIPKNNPPTLIGDFTKS---------FKEFIDACLNKDPS 260 Query: 772 QRPSAKELLQSPFIKSKSRDRELLSKILLNCDIPPAPDRKVRDEKQEKNPKDFSGEWNFD 951 RP+AKELL+ FI S+ L++++ DR R + + + ++ D Sbjct: 261 FRPTAKELLKHKFIVKNSKKTSYLTELI---------DRFKRWKAEGHSDEE------SD 305 Query: 952 IKGKNXXXXXXEDPPGPKTKTSTAENVFYRITLRKRNPK--QNNELQDI 1092 +G + E P P+ +T +K +PK QN E QD+ Sbjct: 306 SEGSDSESSSRESNPHPEWSFTTVR--------KKPDPKKLQNGEEQDL 346
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 160,485,921
Number of Sequences: 369166
Number of extensions: 3261828
Number of successful extensions: 12751
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 9593
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10300
length of database: 68,354,980
effective HSP length: 115
effective length of database: 47,110,455
effective search space used: 18702850635
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Cluster detail
