DrC_00321
- Cluster detail
- GO Category : Not Available
- Consensus Sequence :
BLASTX 2.2.13 [Nov-27-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00321 (1884 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q13813|SPTA2_HUMAN Spectrin alpha chain, brain (Spectrin... 738 0.0 sp|P07751|SPTA2_CHICK Spectrin alpha chain, brain (Spectrin... 737 0.0 sp|P16086|SPTA2_RAT Spectrin alpha chain, brain (Spectrin, ... 736 0.0 sp|P13395|SPTCA_DROME Spectrin alpha chain 735 0.0 sp|P02549|SPTA1_HUMAN Spectrin alpha chain, erythrocyte (Er... 535 e-151 sp|P08032|SPTA1_MOUSE Spectrin alpha chain, erythrocyte (Er... 535 e-151 sp|P16546|SPTA2_MOUSE Spectrin alpha chain, brain (Spectrin... 428 e-119 sp|Q01082|SPTB2_HUMAN Spectrin beta chain, brain 1 (Spectri... 317 1e-85 sp|Q00963|SPTCB_DROME Spectrin beta chain 292 2e-78 sp|Q9QWN8|SPTN2_RAT Spectrin beta chain, brain 2 (Spectrin,... 286 1e-76
>sp|Q13813|SPTA2_HUMAN Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain) Length = 2472 Score = 738 bits (1904), Expect = 0.0 Identities = 369/648 (56%), Positives = 472/648 (72%), Gaps = 21/648 (3%) Frame = +1 Query: 1 WNERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKS 180 W RR YEQ MDLQLFYRDTEQ + W++KQEAFL N D+GDSLDSVEAL++KHEDFEKS Sbjct: 456 WELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKS 515 Query: 181 LAAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNY 360 L+AQEEK LD+ A KL++N HYA DV +RD LL R+ L E+A R+ L DS + Sbjct: 516 LSAQEEKITALDEFATKLIQNNHYAMEDVATRRDALLSRRNALHERAMRRRAQLADSFHL 575 Query: 361 QLFDRDADEIKAWIVEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRG 540 Q F RD+DE+K+W+ EK+KTA+DE YK+P+NLQ KVQKHQ F AE++AN+ RID ++ G Sbjct: 576 QQFFRDSDELKSWVNEKMKTATDEAYKDPSNLQGKVQKHQAFEAELSANQSRIDALEKAG 635 Query: 541 QSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLA 720 Q L+D +H D++ R+ E+ LWK L+ A+++K L +A+ QQQF RNVED+E+WL Sbjct: 636 QKLIDVNHYAKDEVAARMNEVISLWKKLLEATELKGIKLREANQQQQFNRNVEDIELWLY 695 Query: 721 EVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAI 900 EVE L SDD GKDL +V NLQKKH LLE+D+++HQDRID QA QF HFDA+ I Sbjct: 696 EVEGHLASDDYGKDLTNVQNLQKKHALLEADVAAHQDRIDGITIQARQFQDAGHFDAENI 755 Query: 901 KKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRD 1080 KKKQ + RY L+EP+ RK KL D+ +L Q +RD +DEE WI EKEPIA STN G+D Sbjct: 756 KKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVEDEETWIREKEPIAASTNRGKD 815 Query: 1081 LIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDL 1260 LIGVQNL+KKHQA+QAE+ GHEPRI V +G M++ H+A D++ K+ ++ W L Sbjct: 816 LIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLHELNQKWEAL 875 Query: 1261 KNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDAL 1440 K KA +RRQ L+DSL+AQQY ADA+EAESWMREKEP+VGST++GKDEDS EALLKKH+AL Sbjct: 876 KAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEAL 935 Query: 1441 MADIEAYRSTIDSLRTQADACKMQEAPVSDSYGKETVMALYDYQEKNpreVSMRKGDVLT 1620 M+D+ AY S+I +LR QA +C+ Q AP D GKE V+ALYDYQEK+preV+M+KGD+LT Sbjct: 936 MSDLSAYGSSIQALREQAQSCRQQVAPTDDETGKELVLALYDYQEKSpreVTMKKGDILT 995 Query: 1621 LLNSNHKDWWKVEINDRQGHVPAAYVKKVDAMMSDIDPN-APEQITVASQQKNLENQ--- 1788 LLNS +KDWWKVE+NDRQG VPAAYVKK+D S N EQ ++A +Q+ ++NQ Sbjct: 996 LLNSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSASRENLLEEQGSIALRQEQIDNQTRI 1055 Query: 1789 -----------------YENLLSLGKDRRDRLKDSVQAYQLVREANDL 1881 Y +LL LG+ R+ L+ S + + L REAN+L Sbjct: 1056 TKEAGSVSLRMKQVEELYHSLLELGEKRKGMLEKSCKKFMLFREANEL 1103
Score = 438 bits (1126), Expect = e-122
Identities = 222/498 (44%), Positives = 319/498 (64%), Gaps = 2/498 (0%)
Frame = +1
Query: 1 WNERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKS 180
W +RR + +Q ++LQLF+RD EQAE W+A +EAFL D GDSLDSVEALI+KHEDF+K+
Sbjct: 1434 WVQRRMMLDQCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKA 1493
Query: 181 LAAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNY 360
+ QEEK L A++L+ GHYA D++ +R+++L R L+ + ++ L +S
Sbjct: 1494 INVQEEKIAALQAFADQLIAAGHYAKGDISSRRNEVLDRWRRLKAQMIEKRSKLGESQTL 1553
Query: 361 QLFDRDADEIKAWIVEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRG 540
Q F RD DEI+AWI EKL+TASDE+YK+PTN+QSK QKHQ F AE+ AN RI V G
Sbjct: 1554 QQFSRDVDEIEAWISEKLQTASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMG 1613
Query: 541 QSLLDSDH--NKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIW 714
SL++ D ++ R+ L W+ LV S K L +A+ QQ F ++D + W
Sbjct: 1614 NSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFW 1673
Query: 715 LAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDAD 894
L+EVE+ L S+D GKDL SV NL KKH LLE+DIS+H+DR+ QAD + + FD
Sbjct: 1674 LSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTS 1733
Query: 895 AIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVG 1074
+K K+ + R+ K++ R+ KLN++++LHQF+RD DDEE WI EK+ + GS + G
Sbjct: 1734 QVKDKRDTINGRFQKIKSMAASRRAKLNESHRLHQFFRDMDDEESWIKEKKLLVGSEDYG 1793
Query: 1075 RDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWS 1254
RDL GVQNL KKH+ ++AE+ HEP I V + G+K+ D N +I++++ W
Sbjct: 1794 RDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGKEEIQQRLAQFVEHWK 1853
Query: 1255 DLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHD 1434
+LK A R Q L++SLE QQ++A+ E E+W+ EK LV S ++G + + LLKKH+
Sbjct: 1854 ELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHE 1913
Query: 1435 ALMADIEAYRSTIDSLRT 1488
A D ++ ++ + T
Sbjct: 1914 AFETDFTVHKDRVNDVCT 1931
Score = 272 bits (695), Expect = 3e-72
Identities = 140/408 (34%), Positives = 235/408 (57%)
Frame = +1
Query: 256 AADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWIVEKLKTASDEN 435
A D+ ++R +L R +E + LR+ LEDS+ +Q F RDA+E++ WI EKL+ ASDEN
Sbjct: 12 AEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQIASDEN 71
Query: 436 YKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNKSDDIQQRIEELDKLW 615
YK+PTNLQ K+QKHQ F AE+ AN G I + G ++ H S+ I+ R+ EL + W
Sbjct: 72 YKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLMELHRQW 131
Query: 616 KDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKKH 795
+ L+ + K L QA Q++R ED+ W+ + E+ + S++ G+DL V LQKK
Sbjct: 132 ELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKKF 191
Query: 796 NLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNRYSKLQEPLEKRKNKL 975
++D+++H++R++ Q A + + + H + + IK KQ EV + +L+ +R+ KL
Sbjct: 192 EEFQTDMAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLKGLALQRQGKL 251
Query: 976 NDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKHQAIQAEVTGHEPRI 1155
A ++ +F RD D+ WI EKE + S + GRDL VQ L++KH+ ++ ++ E ++
Sbjct: 252 FGAAEVQRFNRDVDETISWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAALEDKV 311
Query: 1156 LEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLLDDSLEAQQYLADAS 1335
+C E ++ + + I+ K +++ W ++ A +R L+DS Q++LAD
Sbjct: 312 KALCAEADRLQQSHPLSATQIQVKREELITNWEQIRTLAAERHARLNDSYRLQRFLADFR 371
Query: 1336 EAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRSTIDS 1479
+ SW+ E + L+ + E D EALL +H +I+A+ + S
Sbjct: 372 DLTSWVTEMKALINADELASDVAGAEALLDRHQEHKGEIDAHEDSFKS 419
Score = 250 bits (639), Expect = 9e-66
Identities = 161/590 (27%), Positives = 293/590 (49%), Gaps = 16/590 (2%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
ER + LQ F D +W+ + +A + +++ + EAL+ +H++ + +
Sbjct: 352 ERHARLNDSYRLQRFLADFRDLTSWVTEMKALINADELASDVAGAEALLDRHQEHKGEID 411
Query: 187 AQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQL 366
A E+ + D+ L+ GHYA+ +V +K L +A L E +LR+ E + QL
Sbjct: 412 AHEDSFKSADESGQALLAAGHYASDEVREKLTVLSEERAALLELWELRRQQYEQCMDLQL 471
Query: 367 FDRDADEIKAWIVEKLKTASDENYKEP-TNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQ 543
F RD +++ W+ ++ +E+ + ++++ ++KH++F ++A E +I +
Sbjct: 472 FYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFAT 531
Query: 544 SLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAE 723
L+ ++H +D+ R + L L + + L + QQF R+ ++++ W+ E
Sbjct: 532 KLIQNNHYAMEDVATRRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDSDELKSWVNE 591
Query: 724 VESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIK 903
+ + +D+ KD +++ +KH E+++S++Q RID+ + + + NH+ D +
Sbjct: 592 -KMKTATDEAYKDPSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYAKDEVA 650
Query: 904 KKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDL 1083
+ EV + + KL E E + KL +A + QF R+ +D E W++E E S + G+DL
Sbjct: 651 ARMNEVISLWKKLLEATELKGIKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDL 710
Query: 1084 IGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLK 1263
VQNL KKH ++A+V H+ RI + + ++ D H+ +I+KK + + + LK
Sbjct: 711 TNVQNLQKKHALLEADVAAHQDRIDGITIQARQFQDAGHFDAENIKKKQEALVARYEALK 770
Query: 1264 NKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALM 1443
R+Q L DSL QQ D + E+W+REKEP+ ST GKD + LLKKH AL
Sbjct: 771 EPMVARKQKLADSLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQ 830
Query: 1444 ADIEAYRSTIDSLRTQADACKMQEAPVSDSYGKETVMALYDYQEKNpreVSMRKGDVLTL 1623
A+I + I ++ TQ ++E + K + L E + S R+ D+
Sbjct: 831 AEIAGHEPRIKAV-TQKGNAMVEEGHFAAEDVKAKLHELNQKWEALKAKASQRRQDLEDS 889
Query: 1624 L-------NSNHKDWWKVEINDRQGHV--------PAAYVKKVDAMMSDI 1728
L ++N + W E G A +KK +A+MSD+
Sbjct: 890 LQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDL 939
Score = 240 bits (613), Expect = 9e-63
Identities = 137/507 (27%), Positives = 271/507 (53%), Gaps = 7/507 (1%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
E+R ++ LQ F RD ++ EAWI+++ + D + +++ +KH+ FE L
Sbjct: 1542 EKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTN-IQSKHQKHQAFEAELH 1600
Query: 187 AQEEKTQRLDDIANKLVENGHYAAAD--VNKKRDDLLIRKANLEEKAKLRKGSLEDSHNY 360
A ++ + + D+ N L+E G A ++ V + L + L +K+ + L++++
Sbjct: 1601 ANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQ 1660
Query: 361 QLFDRDADEIKAWIVEKLKTASDENY-KEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSR 537
Q F+ + W+ E + E+Y K+ ++ + ++KHQ A+I+A+E R+ D+ S+
Sbjct: 1661 QNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQ 1720
Query: 538 GQSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWL 717
SL+ S + ++ + + ++ ++ + S + + L ++ QF R+++D E W+
Sbjct: 1721 ADSLMTSSAFDTSQVKDKRDTINGRFQKIKSMAASRRAKLNESHRLHQFFRDMDDEESWI 1780
Query: 718 AEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADA 897
E + +GS+D G+DL V NL+KKH LE+++++H+ I L + DN +
Sbjct: 1781 KEKKLLVGSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGKEE 1840
Query: 898 IKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGR 1077
I+++ + + +L++ R +L ++ + QF + ++EE WI+EK + S + G
Sbjct: 1841 IQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGD 1900
Query: 1078 DLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSD 1257
L +Q L+KKH+A + + T H+ R+ +VC GQ +I N++ +I K+ + SD
Sbjct: 1901 TLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSD 1960
Query: 1258 LKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDA 1437
L+ A +R+ LD++ Q+ A ESW+ EKE + + ++G+D S + LL K +
Sbjct: 1961 LEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQET 2020
Query: 1438 LMADIEAYR----STIDSLRTQADACK 1506
A ++A++ + I +L+ Q A K
Sbjct: 2021 FDAGLQAFQQEGIANITALKDQLLAAK 2047
Score = 228 bits (582), Expect = 4e-59
Identities = 160/658 (24%), Positives = 304/658 (46%), Gaps = 41/658 (6%)
Frame = +1
Query: 28 QNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQ 207
Q L + R+ E WI +EA + + ++G L+ VE L +K E+F+ +AA EE+
Sbjct: 147 QAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKKFEEFQTDMAAHEERVN 206
Query: 208 RLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADE 387
++ A KL++ H + K+D++ L+ A R+G L + Q F+RD DE
Sbjct: 207 EVNQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLKGLALQRQGKLFGAAEVQRFNRDVDE 266
Query: 388 IKAWIVEKLKT-ASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDH 564
+WI EK + ASD+ ++ ++Q+ ++KH+ ++AA E ++ + + L S
Sbjct: 267 TISWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAALEDKVKALCAEADRLQQSHP 326
Query: 565 NKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGS 744
+ IQ + EEL W+ + + + + L + Q+F+ + D+ W+ E+++ + +
Sbjct: 327 LSATQIQVKREELITNWEQIRTLAAERHARLNDSYRLQRFLADFRDLTSWVTEMKALINA 386
Query: 745 DDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVC 924
D+ D+ L +H + +I +H+D S + + H+ +D +++K +
Sbjct: 387 DELASDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQALLAAGHYASDEVREKLTVLS 446
Query: 925 NRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLI 1104
+ L E E R+ + L FYRD + ++W+ ++E + ++G L V+ L+
Sbjct: 447 EERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALL 506
Query: 1105 KKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRR 1284
KKH+ + ++ E +I + K+I NHYA D+ + D + + + L +A +RR
Sbjct: 507 KKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVATRRDALLSRRNALHERAMRRR 566
Query: 1285 QLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYR 1464
L DS QQ+ D+ E +SW+ EK + E KD + + ++KH A A++ A +
Sbjct: 567 AQLADSFHLQQFFRDSDELKSWVNEKMK-TATDEAYKDPSNLQGKVQKHQAFEAELSANQ 625
Query: 1465 STIDSLRTQADACKMQEAPVSDSYGKETVMALYD---------YQEKNpreVSMRKGDVL 1617
S ID+L Q+ + Y K+ V A + + + + +R+ +
Sbjct: 626 SRIDALEKAG-----QKLIDVNHYAKDEVAARMNEVISLWKKLLEATELKGIKLREANQQ 680
Query: 1618 TLLNSNHKD--WWKVEINDRQGHVP-------------------------AAYVKKVDAM 1716
N N +D W E+ +GH+ AA+ ++D +
Sbjct: 681 QQFNRNVEDIELWLYEV---EGHLASDDYGKDLTNVQNLQKKHALLEADVAAHQDRIDGI 737
Query: 1717 MSDI----DPNAPEQITVASQQKNLENQYENLLSLGKDRRDRLKDSVQAYQLVREAND 1878
D + + +Q+ L +YE L R+ +L DS++ QL R+ D
Sbjct: 738 TIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVED 795
Score = 228 bits (582), Expect = 4e-59
Identities = 126/496 (25%), Positives = 255/496 (51%), Gaps = 3/496 (0%)
Frame = +1
Query: 4 NERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSL 183
++R+ + DLQ F D +WI + ++++ + EAL+ +H++ +
Sbjct: 1329 DQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEI 1388
Query: 184 AAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQ 363
A+ Q + +L+ +GHYA+ ++ +K D L +A+LE+ R+ L+ Q
Sbjct: 1389 DARAGTFQAFEQFGQQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMMLDQCLELQ 1448
Query: 364 LFDRDADEIKAWIVEKLKTASDENYKEP-TNLQSKVQKHQNFLAEIAANEGRIDDVKSRG 540
LF RD ++ + W+ + + E+ + ++++ ++KH++F I E +I +++
Sbjct: 1449 LFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFA 1508
Query: 541 QSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLA 720
L+ + H DI R E+ W+ L + K + L ++ QQF R+V+++E W++
Sbjct: 1509 DQLIAAGHYAKGDISSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWIS 1568
Query: 721 EVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHF--DAD 894
E + Q SD+ KD ++ + +KH E+++ ++ DRI + + + D
Sbjct: 1569 E-KLQTASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSED 1627
Query: 895 AIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVG 1074
A+K + + +++ L + ++ KL +A K F D + W+ E E + S + G
Sbjct: 1628 AVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYG 1687
Query: 1075 RDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWS 1254
+DL V NL+KKHQ ++A+++ HE R+ ++ ++ ++ + + ++ K D + +
Sbjct: 1688 KDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKDKRDTINGRFQ 1747
Query: 1255 DLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHD 1434
+K+ A RR L++S Q+ D + ESW++EK+ LVGS ++G+D + L KKH
Sbjct: 1748 KIKSMAASRRAKLNESHRLHQFFRDMDDEESWIKEKKLLVGSEDYGRDLTGVQNLRKKHK 1807
Query: 1435 ALMADIEAYRSTIDSL 1482
L A++ A+ I +
Sbjct: 1808 RLEAELAAHEPAIQGV 1823
Score = 220 bits (561), Expect = 1e-56
Identities = 124/492 (25%), Positives = 249/492 (50%), Gaps = 1/492 (0%)
Frame = +1
Query: 10 RRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAA 189
RR E + Q F RD E+ E WI ++ + + D + ++ ++KH+ FE + A
Sbjct: 36 RRQKLEDSYRFQFFQRDAEELEKWIQEKLQIASDENYKDPTN-LQGKLQKHQAFEAEVQA 94
Query: 190 QEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLF 369
+LD+ N ++ GH+A+ + + +L + L EK + + L + +
Sbjct: 95 NSGAIVKLDETGNLMISEGHFASETIRTRLMELHRQWELLLEKMREKGIKLLQAQKLVQY 154
Query: 370 DRDADEIKAWIVEKLK-TASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQS 546
R+ +++ WI +K S+E ++ +++ +K + F ++AA+E R+++V
Sbjct: 155 LRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKKFEEFQTDMAAHEERVNEVNQFAAK 214
Query: 547 LLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEV 726
L+ H + + I+ + +E++ W+ L + ++ L A+ Q+F R+V++ W+ E
Sbjct: 215 LIQEQHPEEELIKTKQDEVNAAWQRLKGLALQRQGKLFGAAEVQRFNRDVDETISWIKEK 274
Query: 727 ESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKK 906
E + SDD G+DL SV L +KH LE D+++ +D++ + +AD+ + A I+
Sbjct: 275 EQLMASDDFGRDLASVQALLRKHEGLERDLAALEDKVKALCAEADRLQQSHPLSATQIQV 334
Query: 907 KQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLI 1086
K+ E+ + +++ +R +LND+Y+L +F D D W+ E + + + + D+
Sbjct: 335 KREELITNWEQIRTLAAERHARLNDSYRLQRFLADFRDLTSWVTEMKALINADELASDVA 394
Query: 1087 GVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKN 1266
G + L+ +HQ + E+ HE GQ ++ HYA+ ++ +K+ + + L
Sbjct: 395 GAEALLDRHQEHKGEIDAHEDSFKSADESGQALLAAGHYASDEVREKLTVLSEERAALLE 454
Query: 1267 KADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMA 1446
+ RRQ + ++ Q + D + ++WM ++E + + + G DS EALLKKH+
Sbjct: 455 LWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEK 514
Query: 1447 DIEAYRSTIDSL 1482
+ A I +L
Sbjct: 515 SLSAQEEKITAL 526
Score = 210 bits (534), Expect = 1e-53
Identities = 161/696 (23%), Positives = 310/696 (44%), Gaps = 72/696 (10%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
+R+ + E++ + +R+ + + WI ++EA L + +VG L+ VE L +K +DF+K L
Sbjct: 1082 KRKGMLEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLK 1141
Query: 187 AQEEKTQRLDDIANKLVENGHYA------------------------------------- 255
A E + + ++ +A L G A
Sbjct: 1142 ANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHT 1201
Query: 256 AADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWIVEKLKTASDEN 435
A N ++ L R +L++ A+ R L +H Q F RDADE K WI EK + + +N
Sbjct: 1202 VATFNSIKE-LNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDN 1260
Query: 436 Y-KEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNKSDDIQQRIEELDKL 612
Y + ++Q+ +KH+ F ++AA +++ + + L S ++D+Q++ EL++
Sbjct: 1261 YGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAERLTQSHPESAEDLQEKCTELNQA 1320
Query: 613 WKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKK 792
W L + ++ L + Q+F+ + D+ W+ + + SD+ KD+ L ++
Sbjct: 1321 WSSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLER 1380
Query: 793 HNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNRYSKLQEPLEKRKNK 972
H ++I + +F Q Q + H+ + IK+K + + L++ +R+
Sbjct: 1381 HQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMM 1440
Query: 973 LNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKHQAIQAEVTGHEPR 1152
L+ +L F+RD + E+W+ +E + + G L V+ LIKKH+ + E +
Sbjct: 1441 LDQCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEK 1500
Query: 1153 ILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLLDDSLEAQQYLADA 1332
I + ++I HYA DI + +++ + W LK + ++R L +S QQ+ D
Sbjct: 1501 IAALQAFADQLIAAGHYAKGDISSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDV 1560
Query: 1333 SEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEA----YRSTID-------- 1476
E E+W+ EK S E KD + ++ +KH A A++ A R ID
Sbjct: 1561 DEIEAWISEKLQ-TASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIER 1619
Query: 1477 -SLRTQADACKMQEAPVSDSY------GKETVMALYDYQEKNpreVSMRKGD-----VLT 1620
+ DA K + A ++D + E L + ++ ++ D V
Sbjct: 1620 GACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEA 1679
Query: 1621 LLNSNH--KDWWKVEINDRQGHVPAAYVKKVDAMMSDIDPNAPEQIT--------VASQQ 1770
LL S KD V ++ + A + + + D++ A +T V ++
Sbjct: 1680 LLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKDKR 1739
Query: 1771 KNLENQYENLLSLGKDRRDRLKDSVQAYQLVREAND 1878
+ +++ + S+ RR +L +S + +Q R+ +D
Sbjct: 1740 DTINGRFQKIKSMAASRRAKLNESHRLHQFFRDMDD 1775
Score = 182 bits (462), Expect = 3e-45
Identities = 130/499 (26%), Positives = 234/499 (46%), Gaps = 14/499 (2%)
Frame = +1
Query: 43 QLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQRLDDI 222
Q F R+ E E W+ + E L ++D G L +V+ L +KH E +AA +++ +
Sbjct: 681 QQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEADVAAHQDRIDGITIQ 740
Query: 223 ANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWI 402
A + + GH+ A ++ KK++ L+ R L+E RK L DS Q RD ++ + WI
Sbjct: 741 ARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVEDEETWI 800
Query: 403 VEKLKTASDENY-KEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNKSDD 579
EK A+ N K+ +Q+ ++KHQ AEIA +E RI V +G ++++ H ++D
Sbjct: 801 REKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAED 860
Query: 580 IQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDCGK 759
++ ++ EL++ W+ L + + + +L + QQ+ + + E W+ E E +GS D GK
Sbjct: 861 VKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGK 920
Query: 760 DLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNRYSK 939
D +S L KKH L SD+S++ I + +QA D K+ + Y +
Sbjct: 921 DEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDETGKELVLALYDYQE 980
Query: 940 LQEPLEKRKNK------LN----DAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIG 1089
+ P E K LN D +K+ R ++ + +P ++
Sbjct: 981 -KSpreVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSASR------- 1032
Query: 1090 VQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRD---IEKKIDDMKNLWSDL 1260
+NL+++ +I Q+ ID ++ + ++ ++ L+ L
Sbjct: 1033 -ENLLEEQGSIALR---------------QEQIDNQTRITKEAGSVSLRMKQVEELYHSL 1076
Query: 1261 KNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDAL 1440
+KR+ +L+ S + +A+E + W+ EKE + S E G D + E L KK D
Sbjct: 1077 LELGEKRKGMLEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDF 1136
Query: 1441 MADIEAYRSTIDSLRTQAD 1497
D++A S + + A+
Sbjct: 1137 QKDLKANESRLKDINKVAE 1155
Score = 172 bits (436), Expect = 3e-42
Identities = 122/542 (22%), Positives = 251/542 (46%), Gaps = 50/542 (9%)
Frame = +1
Query: 4 NERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSL 183
++RR E ++ Q ++ D +AE+W+ ++E + + D G DS EAL++KHE L
Sbjct: 880 SQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDL 939
Query: 184 AAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAK----LRKGSL--- 342
+A Q L + A + A ++ +L++ + +EK+ ++KG +
Sbjct: 940 SAYGSSIQALREQAQSCRQQ---VAPTDDETGKELVLALYDYQEKSpreVTMKKGDILTL 996
Query: 343 -----EDSHNYQLFDRDADEIKAWI--VEKLKTASDENYKEPTNLQSKVQKHQNFLAEIA 501
+D ++ DR A++ ++ ++AS EN E IA
Sbjct: 997 LNSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSASRENLLEEQG-------------SIA 1043
Query: 502 ANEGRIDDVKSRGQSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQ 681
+ +ID+ Q+ + + + + R++++++L+ L+ + ++ L ++ +
Sbjct: 1044 LRQEQIDN-----QTRITKE---AGSVSLRMKQVEELYHSLLELGEKRKGMLEKSCKKFM 1095
Query: 682 FIRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQAD 861
R +++ W+ E E+ L S++ G DL V LQKK + + D+ +++ R+ + A+
Sbjct: 1096 LFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAE 1155
Query: 862 QFVHDNHF--DADAIKKKQI----------------------------------EVCNRY 933
+ + A++++++ E+ R+
Sbjct: 1156 DLESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATFNSIKELNERW 1215
Query: 934 SKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKH 1113
LQ+ E+R L A+++ +F+RDAD+ ++WI EK + N G DL VQ L +KH
Sbjct: 1216 RSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKH 1275
Query: 1114 QAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLL 1293
+ + ++ ++ + +++ + + D+++K ++ WS L +AD+R+ L
Sbjct: 1276 EGFERDLAALGDKVNSLGETAERLTQSHPESAEDLQEKCTELNQAWSSLGKRADQRKAKL 1335
Query: 1294 DDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRSTI 1473
DS + Q++L+D + SW+ LV S E KD EALL++H +I+A T
Sbjct: 1336 GDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTF 1395
Query: 1474 DS 1479
+
Sbjct: 1396 QA 1397
Score = 167 bits (422), Expect = 1e-40
Identities = 97/319 (30%), Positives = 172/319 (53%)
Frame = +1
Query: 571 SDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDD 750
++DIQ+R +++ + S ++ L + Q F R+ E++E W+ E + Q+ SD+
Sbjct: 12 AEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQE-KLQIASDE 70
Query: 751 CGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNR 930
KD ++ +KH E+++ ++ I + + + + HF ++ I+ + +E+ +
Sbjct: 71 NYKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLMELHRQ 130
Query: 931 YSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKK 1110
+ L E + ++ KL A KL Q+ R+ +D DWI++KE I S +G+DL V+ L KK
Sbjct: 131 WELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKK 190
Query: 1111 HQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQL 1290
+ Q ++ HE R+ EV K+I H I+ K D++ W LK A +R+
Sbjct: 191 FEEFQTDMAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLKGLALQRQGK 250
Query: 1291 LDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRST 1470
L + E Q++ D E SW++EKE L+ S +FG+D S +ALL+KH+ L D+ A
Sbjct: 251 LFGAAEVQRFNRDVDETISWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAALEDK 310
Query: 1471 IDSLRTQADACKMQEAPVS 1527
+ +L +AD + Q P+S
Sbjct: 311 VKALCAEADRLQ-QSHPLS 328
>sp|P07751|SPTA2_CHICK Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Fodrin alpha chain) Length = 2477 Score = 737 bits (1902), Expect = 0.0 Identities = 369/648 (56%), Positives = 473/648 (72%), Gaps = 21/648 (3%) Frame = +1 Query: 1 WNERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKS 180 W RR YEQ MDLQLFYRDTEQ + W++KQEAFL N D+GDSLDSVEAL++KHEDFEKS Sbjct: 456 WELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKS 515 Query: 181 LAAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNY 360 L+AQEEK LD+ A KL++N HYA DV +RD LL R+ L E+A R+ L DS + Sbjct: 516 LSAQEEKITALDEFATKLIQNNHYAMDDVATRRDALLSRRNALHERAMKRRAQLADSFHL 575 Query: 361 QLFDRDADEIKAWIVEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRG 540 Q F RD+DE+K+W+ EK+KTA+DE YK+P+NLQ KVQKHQ F AE++AN+ RID ++ G Sbjct: 576 QQFFRDSDELKSWVNEKMKTATDEAYKDPSNLQGKVQKHQAFEAELSANQSRIDALEKAG 635 Query: 541 QSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLA 720 Q L+D +H SD++ R+ E+ LWK L+ A+++K L +A+ QQQF RNVED+E+WL Sbjct: 636 QKLIDVNHYASDEVAARMNEVISLWKKLLEATELKGIKLREANQQQQFNRNVEDIELWLY 695 Query: 721 EVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAI 900 EVE L SDD GKDL SV NLQKKH LLE+D+++HQD ID QA QF HFDAD I Sbjct: 696 EVEGHLASDDYGKDLTSVQNLQKKHALLEADVAAHQDPIDGITIQARQFQDAGHFDADNI 755 Query: 901 KKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRD 1080 KKKQ + RY L++P+ RK KL D+ +L Q +RD +DEE WI EKEPIA STN G+D Sbjct: 756 KKKQEALVARYEALKDPMVARKQKLADSLRLQQLFRDIEDEETWIREKEPIAASTNRGKD 815 Query: 1081 LIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDL 1260 LIGVQNL+KKHQA+QAE+ GHEPRI V +G M++ H+A D++ K++++ W L Sbjct: 816 LIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKIKLNELNQKWDSL 875 Query: 1261 KNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDAL 1440 K KA +RRQ L+DSL+AQQY ADA+EA+SWMREKEP+VGST++GKDEDS EALLKKH+AL Sbjct: 876 KAKASQRRQDLEDSLQAQQYFADANEAQSWMREKEPIVGSTDYGKDEDSAEALLKKHEAL 935 Query: 1441 MADIEAYRSTIDSLRTQADACKMQEAPVSDSYGKETVMALYDYQEKNpreVSMRKGDVLT 1620 M+D+ AY S+I +LR QA +C+ Q AP D GKE V+ALYDYQEK+preV+M+KGD+LT Sbjct: 936 MSDLSAYGSSIQALREQAQSCRQQVAPTDDETGKELVLALYDYQEKSpreVTMKKGDILT 995 Query: 1621 LLNSNHKDWWKVEINDRQGHVPAAYVKKVDAMMSDIDPN-APEQITVASQQKNLENQ--- 1788 LLNS +KDWWKVE+NDRQG VPAAYVKK+D S N EQ ++A +Q+ ++NQ Sbjct: 996 LLNSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSASRENLLEEQGSIALRQEQIDNQTLI 1055 Query: 1789 -----------------YENLLSLGKDRRDRLKDSVQAYQLVREANDL 1881 Y +LL LG+ R+ L+ S + + L REAN+L Sbjct: 1056 TKEVGSVSLRMKQVEELYHSLLELGEKRKGMLEKSCKKFMLFREANEL 1103
Score = 419 bits (1076), Expect = e-116
Identities = 216/501 (43%), Positives = 314/501 (62%), Gaps = 7/501 (1%)
Frame = +1
Query: 1 WNERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKS 180
W +RR + +Q ++LQLF+RD EQAE W+A +EAFL D GDSLDSVEALI+KHEDF+K+
Sbjct: 1434 WVQRRMMLDQCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKA 1493
Query: 181 LAAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNY 360
+ QEEK L A++L+ HYA + +R+++L R L+ + ++ L +S
Sbjct: 1494 INVQEEKIAVLQSFADQLIAADHYAKGVIANRRNEVLDRWRRLKAQMIEKRSKLGESQTL 1553
Query: 361 QLFDRDADEIKAWIVEKLKTASDENYKEPTNLQ-----SKVQKHQNFLAEIAANEGRIDD 525
Q F RD DEI+AWI EKL+TASDE+YK+PTN+Q SK QKHQ F AE+ AN RI
Sbjct: 1554 QQFSRDVDEIEAWISEKLQTASDESYKDPTNIQLSKLLSKHQKHQAFEAELHANADRIRG 1613
Query: 526 VKSRGQSLLDSDH--NKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVE 699
V G L++ D ++ R+ L W+ LV S K L +A+ QQ F ++
Sbjct: 1614 VIEMGNPLIERGACAGSEDAVKARLAALADQWEFLVQKSSEKSQKLKEANKQQNFNTGIK 1673
Query: 700 DMEIWLAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDN 879
D + WL+EVE+ L S+D GKDL SV NL KKH LLE+DIS+H+DR+ QAD + +
Sbjct: 1674 DFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSS 1733
Query: 880 HFDADAIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAG 1059
FD +K K+ + R+ +++ R+ KLN++++LHQF+RD DDEE WI EK+ +
Sbjct: 1734 AFDTSQVKDKRETINGRFQRIKSMAAARRAKLNESHRLHQFFRDMDDEESWIKEKKLLVS 1793
Query: 1060 STNVGRDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDM 1239
S + GRDL GVQNL KKH+ ++AE+ HEP I V + G+K+ D N +I++++
Sbjct: 1794 SEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGKEEIQQRLAQF 1853
Query: 1240 KNLWSDLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEAL 1419
+ W +LK A R Q L++SLE QQ++A+ E E+W+ EK LV S ++G + + L
Sbjct: 1854 VDHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGL 1913
Query: 1420 LKKHDALMADIEAYRSTIDSL 1482
LKKH+A D ++ ++ +
Sbjct: 1914 LKKHEAFETDFTVHKDRVNDV 1934
Score = 275 bits (702), Expect = 4e-73
Identities = 147/437 (33%), Positives = 243/437 (55%)
Frame = +1
Query: 256 AADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWIVEKLKTASDEN 435
A D+ ++R +L R +E + LR+ LEDS+ +Q F RDADE+ WI EKL+ ASDEN
Sbjct: 12 AEDIQERRQQVLDRYHRFKELSSLRRQKLEDSYRFQFFQRDADELGKWIQEKLQIASDEN 71
Query: 436 YKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNKSDDIQQRIEELDKLW 615
YK+P+NLQ K+QKHQ F AE+ AN G I + G +++ H S+ I+ R++EL +LW
Sbjct: 72 YKDPSNLQGKLQKHQAFEAEVQANSGAIVKLDETGNQMINEGHFASETIRTRLQELHRLW 131
Query: 616 KDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKKH 795
+ L+ + K L QA QF+R ED+ W+ + E+ + S++ G+DL V LQKK
Sbjct: 132 ELLLEKMREKGVKLLQAQKLVQFLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKKF 191
Query: 796 NLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNRYSKLQEPLEKRKNKL 975
++D+++H++R++ Q A + + + H + + IK KQ EV + +L+ ++R+ KL
Sbjct: 192 EEFQTDLAAHEERVNEVNQFAGKLIQEQHPEEELIKSKQDEVNASWQRLKGLAQQRQGKL 251
Query: 976 NDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKHQAIQAEVTGHEPRI 1155
A ++ +F RD D+ WI EK + S + GRDL VQ L++KH+ ++ ++ ++
Sbjct: 252 FGAAEVQRFNRDVDETISWIKEKGQLMASDDFGRDLASVQALLRKHEGLERDLAAFHHKV 311
Query: 1156 LEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLLDDSLEAQQYLADAS 1335
+C E ++ + I+ K +++ W ++ A +R L+DS Q++LAD
Sbjct: 312 KALCAEADRLQQSHPINASQIQVKREELIANWEQIRTLAAERHARLNDSYRLQRFLADFR 371
Query: 1336 EAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRSTIDSLRTQADACKMQE 1515
+ SW+ E + L+ + E D EALL +H +I+A+ + S A
Sbjct: 372 DLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFRSADESGQALLAAG 431
Query: 1516 APVSDSYGKETVMALYD 1566
SD KE + L D
Sbjct: 432 HYASDEV-KEKLTILSD 447
Score = 246 bits (628), Expect = 2e-64
Identities = 159/590 (26%), Positives = 294/590 (49%), Gaps = 16/590 (2%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
ER + LQ F D +W+ + +A + +++ + + EAL+ +H++ + +
Sbjct: 352 ERHARLNDSYRLQRFLADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEID 411
Query: 187 AQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQL 366
A E+ + D+ L+ GHYA+ +V +K L ++ L E +LR+ E + QL
Sbjct: 412 AHEDSFRSADESGQALLAAGHYASDEVKEKLTILSDERSALLELWELRRQQYEQCMDLQL 471
Query: 367 FDRDADEIKAWIVEKLKTASDENYKEP-TNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQ 543
F RD +++ W+ ++ +E+ + ++++ ++KH++F ++A E +I +
Sbjct: 472 FYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFAT 531
Query: 544 SLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAE 723
L+ ++H DD+ R + L L + + L + QQF R+ ++++ W+ E
Sbjct: 532 KLIQNNHYAMDDVATRRDALLSRRNALHERAMKRRAQLADSFHLQQFFRDSDELKSWVNE 591
Query: 724 VESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIK 903
+ + +D+ KD +++ +KH E+++S++Q RID+ + + + NH+ +D +
Sbjct: 592 -KMKTATDEAYKDPSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYASDEVA 650
Query: 904 KKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDL 1083
+ EV + + KL E E + KL +A + QF R+ +D E W++E E S + G+DL
Sbjct: 651 ARMNEVISLWKKLLEATELKGIKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDL 710
Query: 1084 IGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLK 1263
VQNL KKH ++A+V H+ I + + ++ D H+ +I+KK + + + LK
Sbjct: 711 TSVQNLQKKHALLEADVAAHQDPIDGITIQARQFQDAGHFDADNIKKKQEALVARYEALK 770
Query: 1264 NKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALM 1443
+ R+Q L DSL QQ D + E+W+REKEP+ ST GKD + LLKKH AL
Sbjct: 771 DPMVARKQKLADSLRLQQLFRDIEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQ 830
Query: 1444 ADIEAYRSTIDSLRTQADACKMQEAPVSDSYGKETVMALYDYQEKNpreVSMRKGDVLTL 1623
A+I + I ++ TQ ++E + K + L + + S R+ D+
Sbjct: 831 AEIAGHEPRIKAV-TQKGNAMVEEGHFAAEDVKIKLNELNQKWDSLKAKASQRRQDLEDS 889
Query: 1624 L-------NSNHKDWWKVEINDRQGHV--------PAAYVKKVDAMMSDI 1728
L ++N W E G A +KK +A+MSD+
Sbjct: 890 LQAQQYFADANEAQSWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDL 939
Score = 234 bits (597), Expect = 6e-61
Identities = 137/511 (26%), Positives = 271/511 (53%), Gaps = 11/511 (2%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGD----SLDSVEALIRKHEDFE 174
E+R ++ LQ F RD ++ EAWI+++ + D L + + +KH+ FE
Sbjct: 1542 EKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTNIQLSKLLSKHQKHQAFE 1601
Query: 175 KSLAAQEEKTQRLDDIANKLVENGHYAAAD--VNKKRDDLLIRKANLEEKAKLRKGSLED 348
L A ++ + + ++ N L+E G A ++ V + L + L +K+ + L++
Sbjct: 1602 AELHANADRIRGVIEMGNPLIERGACAGSEDAVKARLAALADQWEFLVQKSSEKSQKLKE 1661
Query: 349 SHNYQLFDRDADEIKAWIVEKLKTASDENY-KEPTNLQSKVQKHQNFLAEIAANEGRIDD 525
++ Q F+ + W+ E + E+Y K+ ++ + ++KHQ A+I+A+E R+ D
Sbjct: 1662 ANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKD 1721
Query: 526 VKSRGQSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDM 705
+ S+ SL+ S + ++ + E ++ ++ + S + + L ++ QF R+++D
Sbjct: 1722 LNSQADSLMTSSAFDTSQVKDKRETINGRFQRIKSMAAARRAKLNESHRLHQFFRDMDDE 1781
Query: 706 EIWLAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHF 885
E W+ E + + S+D G+DL V NL+KKH LE+++++H+ I L + DN
Sbjct: 1782 ESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTI 1841
Query: 886 DADAIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGST 1065
+ I+++ + + + +L++ R +L ++ + QF + ++EE WI+EK + S
Sbjct: 1842 GKEEIQQRLAQFVDHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASE 1901
Query: 1066 NVGRDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKN 1245
+ G L +Q L+KKH+A + + T H+ R+ +VC G+ +I N++ +I K+ +K
Sbjct: 1902 DYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCANGEDLIKKNNHHVENITAKMKGLKG 1961
Query: 1246 LWSDLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLK 1425
SDL+ A +R+ LD++ Q+ A ESW+ EKE + + ++G+D S + LL
Sbjct: 1962 KVSDLEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLT 2021
Query: 1426 KHDALMADIEAYR----STIDSLRTQADACK 1506
K + A ++A++ + I +L+ Q A K
Sbjct: 2022 KQETFDAGLQAFQQEGIANITALKDQLLAAK 2052
Score = 230 bits (587), Expect = 9e-60
Identities = 163/653 (24%), Positives = 302/653 (46%), Gaps = 36/653 (5%)
Frame = +1
Query: 28 QNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQ 207
Q L F R+ E WI +EA + + ++G L+ VE L +K E+F+ LAA EE+
Sbjct: 147 QAQKLVQFLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKKFEEFQTDLAAHEERVN 206
Query: 208 RLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADE 387
++ A KL++ H + K+D++ L+ A+ R+G L + Q F+RD DE
Sbjct: 207 EVNQFAGKLIQEQHPEEELIKSKQDEVNASWQRLKGLAQQRQGKLFGAAEVQRFNRDVDE 266
Query: 388 IKAWIVEKLKT-ASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDH 564
+WI EK + ASD+ ++ ++Q+ ++KH+ ++AA ++ + + L S
Sbjct: 267 TISWIKEKGQLMASDDFGRDLASVQALLRKHEGLERDLAAFHHKVKALCAEADRLQQSHP 326
Query: 565 NKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGS 744
+ IQ + EEL W+ + + + + L + Q+F+ + D+ W+ E+++ + +
Sbjct: 327 INASQIQVKREELIANWEQIRTLAAERHARLNDSYRLQRFLADFRDLTSWVTEMKALINA 386
Query: 745 DDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVC 924
D+ D+ L +H + +I +H+D S + + H+ +D +K+K +
Sbjct: 387 DELANDVAGAEALLDRHQEHKGEIDAHEDSFRSADESGQALLAAGHYASDEVKEKLTILS 446
Query: 925 NRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLI 1104
+ S L E E R+ + L FYRD + ++W+ ++E + ++G L V+ L+
Sbjct: 447 DERSALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALL 506
Query: 1105 KKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRR 1284
KKH+ + ++ E +I + K+I NHYA D+ + D + + + L +A KRR
Sbjct: 507 KKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMDDVATRRDALLSRRNALHERAMKRR 566
Query: 1285 QLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYR 1464
L DS QQ+ D+ E +SW+ EK + E KD + + ++KH A A++ A +
Sbjct: 567 AQLADSFHLQQFFRDSDELKSWVNEKMK-TATDEAYKDPSNLQGKVQKHQAFEAELSANQ 625
Query: 1465 STIDSLRTQADACKMQEAPVSDSYG--KETVMALYD--YQEKNpreVSMRKGDVLTLLNS 1632
S ID+L SD V++L+ + + + +R+ + N
Sbjct: 626 SRIDALEKAGQKLIDVNHYASDEVAARMNEVISLWKKLLEATELKGIKLREANQQQQFNR 685
Query: 1633 NHKD--WWKVEINDRQGHVP-------------------------AAYVKKVDAMMSDI- 1728
N +D W E+ +GH+ AA+ +D +
Sbjct: 686 NVEDIELWLYEV---EGHLASDDYGKDLTSVQNLQKKHALLEADVAAHQDPIDGITIQAR 742
Query: 1729 ---DPNAPEQITVASQQKNLENQYENLLSLGKDRRDRLKDSVQAYQLVREAND 1878
D + + +Q+ L +YE L R+ +L DS++ QL R+ D
Sbjct: 743 QFQDAGHFDADNIKKKQEALVARYEALKDPMVARKQKLADSLRLQQLFRDIED 795
Score = 218 bits (554), Expect = 6e-56
Identities = 122/492 (24%), Positives = 249/492 (50%), Gaps = 1/492 (0%)
Frame = +1
Query: 10 RRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAA 189
RR E + Q F RD ++ WI ++ + + D +++ ++KH+ FE + A
Sbjct: 36 RRQKLEDSYRFQFFQRDADELGKWIQEKLQIASDENYKDP-SNLQGKLQKHQAFEAEVQA 94
Query: 190 QEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLF 369
+LD+ N+++ GH+A+ + + +L L EK + + L + F
Sbjct: 95 NSGAIVKLDETGNQMINEGHFASETIRTRLQELHRLWELLLEKMREKGVKLLQAQKLVQF 154
Query: 370 DRDADEIKAWIVEKLK-TASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQS 546
R+ +++ WI +K S+E ++ +++ +K + F ++AA+E R+++V
Sbjct: 155 LRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKKFEEFQTDLAAHEERVNEVNQFAGK 214
Query: 547 LLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEV 726
L+ H + + I+ + +E++ W+ L ++ ++ L A+ Q+F R+V++ W+ E
Sbjct: 215 LIQEQHPEEELIKSKQDEVNASWQRLKGLAQQRQGKLFGAAEVQRFNRDVDETISWIKEK 274
Query: 727 ESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKK 906
+ SDD G+DL SV L +KH LE D+++ ++ + +AD+ + +A I+
Sbjct: 275 GQLMASDDFGRDLASVQALLRKHEGLERDLAAFHHKVKALCAEADRLQQSHPINASQIQV 334
Query: 907 KQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLI 1086
K+ E+ + +++ +R +LND+Y+L +F D D W+ E + + + + D+
Sbjct: 335 KREELIANWEQIRTLAAERHARLNDSYRLQRFLADFRDLTSWVTEMKALINADELANDVA 394
Query: 1087 GVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKN 1266
G + L+ +HQ + E+ HE GQ ++ HYA+ ++++K+ + + S L
Sbjct: 395 GAEALLDRHQEHKGEIDAHEDSFRSADESGQALLAAGHYASDEVKEKLTILSDERSALLE 454
Query: 1267 KADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMA 1446
+ RRQ + ++ Q + D + ++WM ++E + + + G DS EALLKKH+
Sbjct: 455 LWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEK 514
Query: 1447 DIEAYRSTIDSL 1482
+ A I +L
Sbjct: 515 SLSAQEEKITAL 526
Score = 218 bits (554), Expect = 6e-56
Identities = 125/501 (24%), Positives = 254/501 (50%), Gaps = 8/501 (1%)
Frame = +1
Query: 4 NERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSL 183
++R+ + DLQ F D +WI + ++++ + EAL+ +H++ +
Sbjct: 1329 DQRKEKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEI 1388
Query: 184 AAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQ 363
A+ Q + +L+ GHYA+ ++ +K D L + +LE+ R+ L+ Q
Sbjct: 1389 DARAGTFQAFEQFGQQLLARGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDQCLELQ 1448
Query: 364 LFDRDADEIKAWIVEKLKTASDENYKEP-TNLQSKVQKHQNFLAEIAANEGRIDDVKSRG 540
LF RD ++ + W+ + + E+ + ++++ ++KH++F I E +I ++S
Sbjct: 1449 LFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAVLQSFA 1508
Query: 541 QSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLA 720
L+ +DH I R E+ W+ L + K + L ++ QQF R+V+++E W++
Sbjct: 1509 DQLIAADHYAKGVIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWIS 1568
Query: 721 EVESQLGSDDCGKD-----LNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHF 885
E + Q SD+ KD L+ + + +KH E+++ ++ DRI ++ + +
Sbjct: 1569 E-KLQTASDESYKDPTNIQLSKLLSKHQKHQAFEAELHANADRIRGVIEMGNPLIERGAC 1627
Query: 886 --DADAIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAG 1059
DA+K + + +++ L + ++ KL +A K F D + W+ E E +
Sbjct: 1628 AGSEDAVKARLAALADQWEFLVQKSSEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLA 1687
Query: 1060 STNVGRDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDM 1239
S + G+DL V NL+KKHQ ++A+++ HE R+ ++ ++ ++ + + ++ K + +
Sbjct: 1688 SEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKDKRETI 1747
Query: 1240 KNLWSDLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEAL 1419
+ +K+ A RR L++S Q+ D + ESW++EK+ LV S ++G+D + L
Sbjct: 1748 NGRFQRIKSMAAARRAKLNESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNL 1807
Query: 1420 LKKHDALMADIEAYRSTIDSL 1482
KKH L A++ A+ I +
Sbjct: 1808 RKKHKRLEAELAAHEPAIQGV 1828
Score = 198 bits (503), Expect = 5e-50
Identities = 158/706 (22%), Positives = 309/706 (43%), Gaps = 82/706 (11%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
+R+ + E++ + +R+ + + WI ++EA L N +VG L+ VE L +K +DF+K L
Sbjct: 1082 KRKGMLEKSCKKFMLFREANELQQWINEKEAALTNEEVGADLEQVEVLQKKFDDFQKDLK 1141
Query: 187 AQEEKTQRLDDIANKLVENGHYA------------------------------------- 255
A E + + ++ +AN L G A
Sbjct: 1142 ANESRLKDINKVANDLESEGLMAEEVQAVEHQEVYGMMPRDETDSKTVSPWKSARMMVHT 1201
Query: 256 AADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWIVEKLKTASDEN 435
A N ++ L R +L++ A+ R L + Q F RDADE K WI EK + + +N
Sbjct: 1202 VATFNSIKE-LNERWRSLQQLAEERSQLLGSADEVQRFHRDADETKEWIEEKNQALNTDN 1260
Query: 436 Y-KEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNKSDDIQQRIEELDKL 612
Y + ++Q+ + + F ++AA +++ + Q L+ S ++D+Q++ EL++
Sbjct: 1261 YGHDLASVQALQRNDEGFERDLAALGDKVNSLGETAQRLIQSHPELAEDLQEKCTELNQA 1320
Query: 613 WKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKK 792
W L + ++ L + Q+F+ + D+ W+ + + SD+ KD+ L ++
Sbjct: 1321 WSSLGKRADQRKEKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLER 1380
Query: 793 HNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNRYSKLQEPLEKRKNK 972
H ++I + +F Q Q + H+ + IK+K + + L++ +R+
Sbjct: 1381 HQEHRTEIDARAGTFQAFEQFGQQLLARGHYASPEIKEKLDILDQERTDLEKAWVQRRMM 1440
Query: 973 LNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKHQAIQAEVTGHEPR 1152
L+ +L F+RD + E+W+ +E + + G L V+ LIKKH+ + E +
Sbjct: 1441 LDQCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEK 1500
Query: 1153 ILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLLDDSLEAQQYLADA 1332
I + + ++I +HYA I + +++ + W LK + ++R L +S QQ+ D
Sbjct: 1501 IAVLQSFADQLIAADHYAKGVIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDV 1560
Query: 1333 SEAESWMREKEPLVGSTEFGKDEDSTE--ALLKKHDALMADIEAYRSTIDSLR------- 1485
E E+W+ EK S E KD + + LL KH A + D +R
Sbjct: 1561 DEIEAWISEKLQ-TASDESYKDPTNIQLSKLLSKHQKHQAFEAELHANADRIRGVIEMGN 1619
Query: 1486 --TQADACKMQEAPVSDSYGKETVMALYD-----YQEKNpreVSMRKGDVLTLLNSNHK- 1641
+ AC E V K + AL D Q+ + + +++ + N+ K
Sbjct: 1620 PLIERGACAGSEDAV-----KARLAALADQWEFLVQKSSEKSQKLKEANKQQNFNTGIKD 1674
Query: 1642 -DWWKVEIND------------------RQGHVPAAYVKKVDAMMSDIDPNAPEQIT--- 1755
D+W E+ ++ + A + + + D++ A +T
Sbjct: 1675 FDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSA 1734
Query: 1756 -----VASQQKNLENQYENLLSLGKDRRDRLKDSVQAYQLVREAND 1878
V +++ + +++ + S+ RR +L +S + +Q R+ +D
Sbjct: 1735 FDTSQVKDKRETINGRFQRIKSMAAARRAKLNESHRLHQFFRDMDD 1780
Score = 177 bits (449), Expect = 9e-44
Identities = 128/499 (25%), Positives = 232/499 (46%), Gaps = 14/499 (2%)
Frame = +1
Query: 43 QLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQRLDDI 222
Q F R+ E E W+ + E L ++D G L SV+ L +KH E +AA ++ +
Sbjct: 681 QQFNRNVEDIELWLYEVEGHLASDDYGKDLTSVQNLQKKHALLEADVAAHQDPIDGITIQ 740
Query: 223 ANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWI 402
A + + GH+ A ++ KK++ L+ R L++ RK L DS Q RD ++ + WI
Sbjct: 741 ARQFQDAGHFDADNIKKKQEALVARYEALKDPMVARKQKLADSLRLQQLFRDIEDEETWI 800
Query: 403 VEKLKTASDENY-KEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNKSDD 579
EK A+ N K+ +Q+ ++KHQ AEIA +E RI V +G ++++ H ++D
Sbjct: 801 REKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAED 860
Query: 580 IQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDCGK 759
++ ++ EL++ W L + + + +L + QQ+ + + + W+ E E +GS D GK
Sbjct: 861 VKIKLNELNQKWDSLKAKASQRRQDLEDSLQAQQYFADANEAQSWMREKEPIVGSTDYGK 920
Query: 760 DLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNRYSK 939
D +S L KKH L SD+S++ I + +QA D K+ + Y +
Sbjct: 921 DEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPTDDETGKELVLALYDYQE 980
Query: 940 LQEPLEKRKNK------LN----DAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIG 1089
+ P E K LN D +K+ R ++ + +P ++
Sbjct: 981 -KSpreVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSASR------- 1032
Query: 1090 VQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEK---KIDDMKNLWSDL 1260
+NL+++ +I Q+ ID +++ ++ ++ L+ L
Sbjct: 1033 -ENLLEEQGSIALR---------------QEQIDNQTLITKEVGSVSLRMKQVEELYHSL 1076
Query: 1261 KNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDAL 1440
+KR+ +L+ S + +A+E + W+ EKE + + E G D + E L KK D
Sbjct: 1077 LELGEKRKGMLEKSCKKFMLFREANELQQWINEKEAALTNEEVGADLEQVEVLQKKFDDF 1136
Query: 1441 MADIEAYRSTIDSLRTQAD 1497
D++A S + + A+
Sbjct: 1137 QKDLKANESRLKDINKVAN 1155
Score = 166 bits (420), Expect = 2e-40
Identities = 121/542 (22%), Positives = 248/542 (45%), Gaps = 50/542 (9%)
Frame = +1
Query: 4 NERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSL 183
++RR E ++ Q ++ D +A++W+ ++E + + D G DS EAL++KHE L
Sbjct: 880 SQRRQDLEDSLQAQQYFADANEAQSWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDL 939
Query: 184 AAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAK----LRKGSL--- 342
+A Q L + A + A ++ +L++ + +EK+ ++KG +
Sbjct: 940 SAYGSSIQALREQAQSCRQQ---VAPTDDETGKELVLALYDYQEKSpreVTMKKGDILTL 996
Query: 343 -----EDSHNYQLFDRDADEIKAWI--VEKLKTASDENYKEPTNLQSKVQKHQNFLAEIA 501
+D ++ DR A++ ++ ++AS EN E IA
Sbjct: 997 LNSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSASRENLLEEQG-------------SIA 1043
Query: 502 ANEGRIDDVKSRGQSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQ 681
+ +ID+ Q+L+ + + R++++++L+ L+ + ++ L ++ +
Sbjct: 1044 LRQEQIDN-----QTLITKEVGS---VSLRMKQVEELYHSLLELGEKRKGMLEKSCKKFM 1095
Query: 682 FIRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQAD 861
R +++ W+ E E+ L +++ G DL V LQKK + + D+ +++ R+ + A+
Sbjct: 1096 LFREANELQQWINEKEAALTNEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAN 1155
Query: 862 QFVHDNHF--DADAIKKKQI----------------------------------EVCNRY 933
+ + A++ +++ E+ R+
Sbjct: 1156 DLESEGLMAEEVQAVEHQEVYGMMPRDETDSKTVSPWKSARMMVHTVATFNSIKELNERW 1215
Query: 934 SKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKH 1113
LQ+ E+R L A ++ +F+RDAD+ ++WI EK + N G DL VQ L +
Sbjct: 1216 RSLQQLAEERSQLLGSADEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRND 1275
Query: 1114 QAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLL 1293
+ + ++ ++ + Q++I + D+++K ++ WS L +AD+R++ L
Sbjct: 1276 EGFERDLAALGDKVNSLGETAQRLIQSHPELAEDLQEKCTELNQAWSSLGKRADQRKEKL 1335
Query: 1294 DDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRSTI 1473
DS + Q++L+D + SW+ LV S E KD EALL++H +I+A T
Sbjct: 1336 GDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTF 1395
Query: 1474 DS 1479
+
Sbjct: 1396 QA 1397
>sp|P16086|SPTA2_RAT Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain) Length = 2472 Score = 736 bits (1901), Expect = 0.0 Identities = 368/648 (56%), Positives = 473/648 (72%), Gaps = 21/648 (3%) Frame = +1 Query: 1 WNERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKS 180 W RR YEQ MDLQLFYRDTEQ + W++KQEAFL N D+GDSLDSVEAL++KHEDFEKS Sbjct: 456 WELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKS 515 Query: 181 LAAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNY 360 L+AQEEK LD+ A KL++N HYA DV +RD LL R+ L E+A R+ L DS + Sbjct: 516 LSAQEEKITALDEFATKLIQNNHYAMEDVATRRDALLSRRNALHERAMHRRAQLADSFHL 575 Query: 361 QLFDRDADEIKAWIVEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRG 540 Q F RD+DE+K+W+ EK+KTA+DE YK+P+NLQ KVQKHQ F AE++AN+ RID ++ G Sbjct: 576 QQFFRDSDELKSWVNEKMKTATDEAYKDPSNLQGKVQKHQAFEAELSANQSRIDALEKAG 635 Query: 541 QSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLA 720 Q L+D +H +++ R+ E+ LWK L+ A+++K L +A+ QQQF RNVED+E+WL Sbjct: 636 QKLIDVNHYAKEEVAARMNEVISLWKKLLEATELKGVKLREANQQQQFNRNVEDIELWLY 695 Query: 721 EVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAI 900 EVE L SDD GKDL +V NLQKKH LLE+D+++HQDRID QA QF HFDA+ I Sbjct: 696 EVEGHLASDDYGKDLTNVQNLQKKHALLEADVAAHQDRIDGITIQARQFQDAGHFDAENI 755 Query: 901 KKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRD 1080 KKKQ + RY L+EP+ RK KL D+ +L Q +RD +DEE WI EKEPIA STN G+D Sbjct: 756 KKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVEDEETWIREKEPIAASTNRGKD 815 Query: 1081 LIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDL 1260 LIGVQNL+KKHQA+QAE+ GHEPRI V +G M++ H+A D++ K+ ++ W L Sbjct: 816 LIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLSELNQKWEAL 875 Query: 1261 KNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDAL 1440 K KA +RRQ L+DSL+AQQY ADA+EAESWMREKEP+VGST++GKDEDS EALLKKH+AL Sbjct: 876 KAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEAL 935 Query: 1441 MADIEAYRSTIDSLRTQADACKMQEAPVSDSYGKETVMALYDYQEKNpreVSMRKGDVLT 1620 M+D+ AY S+I +LR QA +C+ Q AP+ D GKE V+ALYDYQEK+preV+M+KGD+LT Sbjct: 936 MSDLSAYGSSIQALREQAQSCRQQVAPMDDETGKELVLALYDYQEKSpreVTMKKGDILT 995 Query: 1621 LLNSNHKDWWKVEINDRQGHVPAAYVKKVDAMMSDIDPN-APEQITVASQQKNLENQ--- 1788 LLNS +KDWWKVE+NDRQG VPAAYVKK+D S N EQ ++A +Q ++NQ Sbjct: 996 LLNSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSASRENLLEEQGSIALRQGQIDNQTRI 1055 Query: 1789 -----------------YENLLSLGKDRRDRLKDSVQAYQLVREANDL 1881 Y++LL LG+ R+ L+ S + + L REAN+L Sbjct: 1056 TKEAGSVSLRMKQVEELYQSLLELGEKRKGMLEKSCKKFMLFREANEL 1103
Score = 428 bits (1101), Expect = e-119
Identities = 218/498 (43%), Positives = 316/498 (63%), Gaps = 2/498 (0%)
Frame = +1
Query: 1 WNERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKS 180
W +RR + + ++LQLF+RD EQAE W+A +EAFL D GDSLDSVEALI+KHEDF+K+
Sbjct: 1434 WVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKA 1493
Query: 181 LAAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNY 360
+ QEEK L A++L+ HYA D+ +R+++L R L+ + ++ L +S
Sbjct: 1494 INVQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVLDRWRRLKAQMIEKRSKLGESQTL 1553
Query: 361 QLFDRDADEIKAWIVEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRG 540
Q F RD DEI+AWI EKL+TASDE+YK+PTN+QSK QKHQ F AE+ AN RI V G
Sbjct: 1554 QQFSRDVDEIEAWISEKLQTASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMG 1613
Query: 541 QSLLDSDH--NKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIW 714
SL++ D ++ R+ L W+ LV S K L +A+ QQ F ++D + W
Sbjct: 1614 NSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFW 1673
Query: 715 LAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDAD 894
L+EVE+ L S+D GKDL SV NL KKH LLE+DIS+H+DR+ QAD + + FD
Sbjct: 1674 LSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTS 1733
Query: 895 AIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVG 1074
+K+K+ + R+ K++ R+ KL+++++LHQF+RD DDEE WI EK+ + S + G
Sbjct: 1734 QVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYG 1793
Query: 1075 RDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWS 1254
RDL GVQNL KKH+ ++AE+ HEP I V + G+K+ D N +I++++ W
Sbjct: 1794 RDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWK 1853
Query: 1255 DLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHD 1434
+LK A R Q L++SLE QQ++A+ E E+W+ EK LV S ++G + + LLKKH+
Sbjct: 1854 ELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHE 1913
Query: 1435 ALMADIEAYRSTIDSLRT 1488
A D ++ ++ + T
Sbjct: 1914 AFETDFTVHKDRVNDVCT 1931
Score = 275 bits (702), Expect = 4e-73
Identities = 141/408 (34%), Positives = 235/408 (57%)
Frame = +1
Query: 256 AADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWIVEKLKTASDEN 435
A D+ ++R +L R +E + LR+ LEDS+ +Q F RDA+E++ WI EKL+ ASDEN
Sbjct: 12 AEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQVASDEN 71
Query: 436 YKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNKSDDIQQRIEELDKLW 615
YK+PTNLQ K+QKHQ F AE+ AN G I + G ++ H S+ I+ R+ EL + W
Sbjct: 72 YKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLMELHRQW 131
Query: 616 KDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKKH 795
+ L+ + K L QA Q++R ED+ W+ + E+ + S++ G+DL V LQKK
Sbjct: 132 ELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKKF 191
Query: 796 NLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNRYSKLQEPLEKRKNKL 975
++D+++H++R++ Q A + + + H + + IK KQ EV + +L+ +R+ KL
Sbjct: 192 EEFQTDLAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQEEVNAAWQRLKGLALQRQGKL 251
Query: 976 NDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKHQAIQAEVTGHEPRI 1155
A ++ +F RD D+ WI EKE + S + GRDL VQ L++KH+ ++ ++ E ++
Sbjct: 252 FGAAEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAALEDKV 311
Query: 1156 LEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLLDDSLEAQQYLADAS 1335
+C E ++ + + I+ K +++ W ++ A +R LDDS Q++LAD
Sbjct: 312 KALCAEADRLQQSHPLSANQIQVKREELITNWEQIRTLAAERHARLDDSYRLQRFLADFR 371
Query: 1336 EAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRSTIDS 1479
+ SW+ E + L+ + E D EALL +H +I+A+ + S
Sbjct: 372 DLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFKS 419
Score = 251 bits (640), Expect = 7e-66
Identities = 160/590 (27%), Positives = 295/590 (50%), Gaps = 16/590 (2%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
ER + + LQ F D +W+ + +A + +++ + + EAL+ +H++ + +
Sbjct: 352 ERHARLDDSYRLQRFLADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEID 411
Query: 187 AQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQL 366
A E+ + D+ L+ GHYA+ +V +K L +A L E +LR+ E + QL
Sbjct: 412 AHEDSFKSADESGQALLAAGHYASDEVREKLSILSEERAALLELWELRRQQYEQCMDLQL 471
Query: 367 FDRDADEIKAWIVEKLKTASDENYKEP-TNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQ 543
F RD +++ W+ ++ +E+ + ++++ ++KH++F ++A E +I +
Sbjct: 472 FYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFAT 531
Query: 544 SLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAE 723
L+ ++H +D+ R + L L + + L + QQF R+ ++++ W+ E
Sbjct: 532 KLIQNNHYAMEDVATRRDALLSRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNE 591
Query: 724 VESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIK 903
+ + +D+ KD +++ +KH E+++S++Q RID+ + + + NH+ + +
Sbjct: 592 -KMKTATDEAYKDPSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYAKEEVA 650
Query: 904 KKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDL 1083
+ EV + + KL E E + KL +A + QF R+ +D E W++E E S + G+DL
Sbjct: 651 ARMNEVISLWKKLLEATELKGVKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDL 710
Query: 1084 IGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLK 1263
VQNL KKH ++A+V H+ RI + + ++ D H+ +I+KK + + + LK
Sbjct: 711 TNVQNLQKKHALLEADVAAHQDRIDGITIQARQFQDAGHFDAENIKKKQEALVARYEALK 770
Query: 1264 NKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALM 1443
R+Q L DSL QQ D + E+W+REKEP+ ST GKD + LLKKH AL
Sbjct: 771 EPMVARKQKLADSLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQ 830
Query: 1444 ADIEAYRSTIDSLRTQADACKMQEAPVSDSYGKETVMALYDYQEKNpreVSMRKGDVLTL 1623
A+I + I ++ TQ ++E + K + L E + S R+ D+
Sbjct: 831 AEIAGHEPRIKAV-TQKGNAMVEEGHFAAEDVKAKLSELNQKWEALKAKASQRRQDLEDS 889
Query: 1624 L-------NSNHKDWWKVEINDRQGHV--------PAAYVKKVDAMMSDI 1728
L ++N + W E G A +KK +A+MSD+
Sbjct: 890 LQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDL 939
Score = 239 bits (611), Expect = 2e-62
Identities = 156/603 (25%), Positives = 305/603 (50%), Gaps = 11/603 (1%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
E+R ++ LQ F RD ++ EAWI+++ + D + +++ +KH+ FE L
Sbjct: 1542 EKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTN-IQSKHQKHQAFEAELH 1600
Query: 187 AQEEKTQRLDDIANKLVENGHYAAAD--VNKKRDDLLIRKANLEEKAKLRKGSLEDSHNY 360
A ++ + + D+ N L+E G A ++ V + L + L +K+ + L++++
Sbjct: 1601 ANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQ 1660
Query: 361 QLFDRDADEIKAWIVEKLKTASDENY-KEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSR 537
Q F+ + W+ E + E+Y K+ ++ + ++KHQ A+I+A+E R+ D+ S+
Sbjct: 1661 QNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQ 1720
Query: 538 GQSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWL 717
SL+ S + ++++ + ++ ++ + S + + L+++ QF R+++D E W+
Sbjct: 1721 ADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWI 1780
Query: 718 AEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADA 897
E + + S+D G+DL V NL+KKH LE+++++H+ I L + DN +
Sbjct: 1781 KEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGQEE 1840
Query: 898 IKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGR 1077
I+++ + + +L++ R +L ++ + QF + ++EE WI+EK + S + G
Sbjct: 1841 IQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGD 1900
Query: 1078 DLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSD 1257
L +Q L+KKH+A + + T H+ R+ +VC GQ +I N++ +I K+ + SD
Sbjct: 1901 TLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSD 1960
Query: 1258 LKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDA 1437
L+ A +R+ LD++ Q+ A ESW+ EKE + + ++G+D S + LL K +
Sbjct: 1961 LEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQET 2020
Query: 1438 LMADIEAYRSTIDSLRTQADACKMQEAPVSDSYGKETVMALYDYQEK--NpreVSMRKGD 1611
A ++A++ QE + + K+ ++A Q K R S+ K
Sbjct: 2021 FDAGLQAFQ---------------QEGIANITALKDQLLAAKHIQSKAIEARHASLMKRW 2065
Query: 1612 VLTLLNSNHKDWWKVEINDRQGH------VPAAYVKKVDAMMSDIDPNAPEQITVASQQK 1773
L NS + K ++ + Q H + + KK A S + NA E +T +
Sbjct: 2066 TQLLANSATR---KKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFE-NAEEDLTDPVRCN 2121
Query: 1774 NLE 1782
+LE
Sbjct: 2122 SLE 2124
Score = 227 bits (579), Expect = 8e-59
Identities = 162/658 (24%), Positives = 303/658 (46%), Gaps = 41/658 (6%)
Frame = +1
Query: 28 QNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQ 207
Q L + R+ E WI +EA + + ++G L+ VE L +K E+F+ LAA EE+
Sbjct: 147 QAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKKFEEFQTDLAAHEERVN 206
Query: 208 RLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADE 387
++ A KL++ H + K++++ L+ A R+G L + Q F+RD DE
Sbjct: 207 EVNQFAAKLIQEQHPEEELIKTKQEEVNAAWQRLKGLALQRQGKLFGAAEVQRFNRDVDE 266
Query: 388 IKAWIVEKLKT-ASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDH 564
WI EK + ASD+ ++ ++Q+ ++KH+ ++AA E ++ + + L S
Sbjct: 267 TIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAALEDKVKALCAEADRLQQSHP 326
Query: 565 NKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGS 744
++ IQ + EEL W+ + + + + L + Q+F+ + D+ W+ E+++ + +
Sbjct: 327 LSANQIQVKREELITNWEQIRTLAAERHARLDDSYRLQRFLADFRDLTSWVTEMKALINA 386
Query: 745 DDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVC 924
D+ D+ L +H + +I +H+D S + + H+ +D +++K +
Sbjct: 387 DELANDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQALLAAGHYASDEVREKLSILS 446
Query: 925 NRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLI 1104
+ L E E R+ + L FYRD + ++W+ ++E + ++G L V+ L+
Sbjct: 447 EERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALL 506
Query: 1105 KKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRR 1284
KKH+ + ++ E +I + K+I NHYA D+ + D + + + L +A RR
Sbjct: 507 KKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAMEDVATRRDALLSRRNALHERAMHRR 566
Query: 1285 QLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYR 1464
L DS QQ+ D+ E +SW+ EK + E KD + + ++KH A A++ A +
Sbjct: 567 AQLADSFHLQQFFRDSDELKSWVNEKMK-TATDEAYKDPSNLQGKVQKHQAFEAELSANQ 625
Query: 1465 STIDSLRTQADACKMQEAPVSDSYGKETVMALYD---------YQEKNpreVSMRKGDVL 1617
S ID+L Q+ + Y KE V A + + + V +R+ +
Sbjct: 626 SRIDALEKAG-----QKLIDVNHYAKEEVAARMNEVISLWKKLLEATELKGVKLREANQQ 680
Query: 1618 TLLNSNHKD--WWKVEINDRQGHVP-------------------------AAYVKKVDAM 1716
N N +D W E+ +GH+ AA+ ++D +
Sbjct: 681 QQFNRNVEDIELWLYEV---EGHLASDDYGKDLTNVQNLQKKHALLEADVAAHQDRIDGI 737
Query: 1717 MSDI----DPNAPEQITVASQQKNLENQYENLLSLGKDRRDRLKDSVQAYQLVREAND 1878
D + + +Q+ L +YE L R+ +L DS++ QL R+ D
Sbjct: 738 TIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVED 795
Score = 226 bits (576), Expect = 2e-58
Identities = 125/496 (25%), Positives = 253/496 (51%), Gaps = 3/496 (0%)
Frame = +1
Query: 4 NERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSL 183
++R+ + DLQ F D +WI + ++++ + EAL+ +H++ +
Sbjct: 1329 DQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEI 1388
Query: 184 AAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQ 363
A+ Q + +L+ +GHYA+ ++ +K D L + +LE+ R+ L+ Q
Sbjct: 1389 DARAGTFQAFEQFGQQLLAHGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQ 1448
Query: 364 LFDRDADEIKAWIVEKLKTASDENYKEP-TNLQSKVQKHQNFLAEIAANEGRIDDVKSRG 540
LF RD ++ + W+ + + E+ + ++++ ++KH++F I E +I +++
Sbjct: 1449 LFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFA 1508
Query: 541 QSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLA 720
L+ DH DI R E+ W+ L + K + L ++ QQF R+V+++E W++
Sbjct: 1509 DQLIAVDHYAKGDIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWIS 1568
Query: 721 EVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHF--DAD 894
E + Q SD+ KD ++ + +KH E+++ ++ DRI + + + D
Sbjct: 1569 E-KLQTASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSED 1627
Query: 895 AIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVG 1074
A+K + + +++ L + ++ KL +A K F D + W+ E E + S + G
Sbjct: 1628 AVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYG 1687
Query: 1075 RDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWS 1254
+DL V NL+KKHQ ++A+++ HE R+ ++ ++ ++ + + +++K D + +
Sbjct: 1688 KDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQ 1747
Query: 1255 DLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHD 1434
+K+ A RR L +S Q+ D + ESW++EK+ LV S ++G+D + L KKH
Sbjct: 1748 KIKSMATSRRAKLSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHK 1807
Query: 1435 ALMADIEAYRSTIDSL 1482
L A++ A+ I +
Sbjct: 1808 RLEAELAAHEPAIQGV 1823
Score = 220 bits (561), Expect = 1e-56
Identities = 124/492 (25%), Positives = 250/492 (50%), Gaps = 1/492 (0%)
Frame = +1
Query: 10 RRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAA 189
RR E + Q F RD E+ E WI ++ + + D + ++ ++KH+ FE + A
Sbjct: 36 RRQKLEDSYRFQFFQRDAEELEKWIQEKLQVASDENYKDPTN-LQGKLQKHQAFEAEVQA 94
Query: 190 QEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLF 369
+LD+ N ++ GH+A+ + + +L + L EK + + L + +
Sbjct: 95 NSGAIVKLDETGNLMISEGHFASETIRTRLMELHRQWELLLEKMREKGIKLLQAQKLVQY 154
Query: 370 DRDADEIKAWIVEKLK-TASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQS 546
R+ +++ WI +K S+E ++ +++ +K + F ++AA+E R+++V
Sbjct: 155 LRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKKFEEFQTDLAAHEERVNEVNQFAAK 214
Query: 547 LLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEV 726
L+ H + + I+ + EE++ W+ L + ++ L A+ Q+F R+V++ W+ E
Sbjct: 215 LIQEQHPEEELIKTKQEEVNAAWQRLKGLALQRQGKLFGAAEVQRFNRDVDETIGWIKEK 274
Query: 727 ESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKK 906
E + SDD G+DL SV L +KH LE D+++ +D++ + +AD+ + A+ I+
Sbjct: 275 EQLMASDDFGRDLASVQALLRKHEGLERDLAALEDKVKALCAEADRLQQSHPLSANQIQV 334
Query: 907 KQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLI 1086
K+ E+ + +++ +R +L+D+Y+L +F D D W+ E + + + + D+
Sbjct: 335 KREELITNWEQIRTLAAERHARLDDSYRLQRFLADFRDLTSWVTEMKALINADELANDVA 394
Query: 1087 GVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKN 1266
G + L+ +HQ + E+ HE GQ ++ HYA+ ++ +K+ + + L
Sbjct: 395 GAEALLDRHQEHKGEIDAHEDSFKSADESGQALLAAGHYASDEVREKLSILSEERAALLE 454
Query: 1267 KADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMA 1446
+ RRQ + ++ Q + D + ++WM ++E + + + G DS EALLKKH+
Sbjct: 455 LWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEK 514
Query: 1447 DIEAYRSTIDSL 1482
+ A I +L
Sbjct: 515 SLSAQEEKITAL 526
Score = 209 bits (531), Expect = 3e-53
Identities = 161/696 (23%), Positives = 312/696 (44%), Gaps = 72/696 (10%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
+R+ + E++ + +R+ + + WI ++EA L + +VG L+ VE L +K +DF+K L
Sbjct: 1082 KRKGMLEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLK 1141
Query: 187 AQEEKTQRLDDIANKLVENGHYA------------------------------------- 255
A E + + ++ +A L G A
Sbjct: 1142 ANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDEADSKTASPWKSARLMVHT 1201
Query: 256 AADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWIVEKLKTASDEN 435
A N ++ L R +L++ A+ R L +H Q F RDADE K WI EK + + +N
Sbjct: 1202 VATFNSIKE-LNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDN 1260
Query: 436 Y-KEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNKSDDIQQRIEELDKL 612
Y + ++Q+ +KH+ F ++AA +++ + Q L+ S ++D++++ EL++
Sbjct: 1261 YGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAQRLIQSHPESAEDLKEKCTELNQA 1320
Query: 613 WKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKK 792
W L + ++ L + Q+F+ + D+ W+ + + SD+ KD+ L ++
Sbjct: 1321 WTSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLER 1380
Query: 793 HNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNRYSKLQEPLEKRKNK 972
H ++I + +F Q Q + H+ + IK+K + + L++ +R+
Sbjct: 1381 HQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKEKLDILDQERTDLEKAWVQRRMM 1440
Query: 973 LNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKHQAIQAEVTGHEPR 1152
L+ +L F+RD + E+W+ +E + + G L V+ LIKKH+ + E +
Sbjct: 1441 LDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEK 1500
Query: 1153 ILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLLDDSLEAQQYLADA 1332
I + ++I +HYA DI + +++ + W LK + ++R L +S QQ+ D
Sbjct: 1501 IAALQAFADQLIAVDHYAKGDIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDV 1560
Query: 1333 SEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEA----YRSTID-------- 1476
E E+W+ EK S E KD + ++ +KH A A++ A R ID
Sbjct: 1561 DEIEAWISEKLQ-TASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIER 1619
Query: 1477 -SLRTQADACKMQEAPVSDSY------GKETVMALYDYQEKNpreVSMRKGD-----VLT 1620
+ DA K + A ++D + E L + ++ ++ D V
Sbjct: 1620 GACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEA 1679
Query: 1621 LLNSNH--KDWWKVEINDRQGHVPAAYVKKVDAMMSDIDPNAPEQIT--------VASQQ 1770
LL S KD V ++ + A + + + D++ A +T V ++
Sbjct: 1680 LLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKR 1739
Query: 1771 KNLENQYENLLSLGKDRRDRLKDSVQAYQLVREAND 1878
+ +++ + S+ RR +L +S + +Q R+ +D
Sbjct: 1740 DTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDD 1775
Score = 181 bits (460), Expect = 5e-45
Identities = 126/498 (25%), Positives = 233/498 (46%), Gaps = 13/498 (2%)
Frame = +1
Query: 43 QLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQRLDDI 222
Q F R+ E E W+ + E L ++D G L +V+ L +KH E +AA +++ +
Sbjct: 681 QQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEADVAAHQDRIDGITIQ 740
Query: 223 ANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWI 402
A + + GH+ A ++ KK++ L+ R L+E RK L DS Q RD ++ + WI
Sbjct: 741 ARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVEDEETWI 800
Query: 403 VEKLKTASDENY-KEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNKSDD 579
EK A+ N K+ +Q+ ++KHQ AEIA +E RI V +G ++++ H ++D
Sbjct: 801 REKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAED 860
Query: 580 IQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDCGK 759
++ ++ EL++ W+ L + + + +L + QQ+ + + E W+ E E +GS D GK
Sbjct: 861 VKAKLSELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGK 920
Query: 760 DLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHD-NHFDADAIKKKQIEVCNRYS 936
D +S L KKH L SD+S++ I + +QA D + K+ + + +
Sbjct: 921 DEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPMDDETGKELVLALYDYQE 980
Query: 937 KLQEPLEKRKNKL--------NDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGV 1092
K + +K + D +K+ R ++ + +P ++
Sbjct: 981 KSpreVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSASR-------- 1032
Query: 1093 QNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRD---IEKKIDDMKNLWSDLK 1263
+NL+++ +I Q ID ++ + ++ ++ L+ L
Sbjct: 1033 ENLLEEQGSIALR---------------QGQIDNQTRITKEAGSVSLRMKQVEELYQSLL 1077
Query: 1264 NKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALM 1443
+KR+ +L+ S + +A+E + W+ EKE + S E G D + E L KK D
Sbjct: 1078 ELGEKRKGMLEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQ 1137
Query: 1444 ADIEAYRSTIDSLRTQAD 1497
D++A S + + A+
Sbjct: 1138 KDLKANESRLKDINKVAE 1155
Score = 177 bits (448), Expect = 1e-43
Identities = 124/542 (22%), Positives = 254/542 (46%), Gaps = 50/542 (9%)
Frame = +1
Query: 4 NERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSL 183
++RR E ++ Q ++ D +AE+W+ ++E + + D G DS EAL++KHE L
Sbjct: 880 SQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDL 939
Query: 184 AAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAK----LRKGSL--- 342
+A Q L + A + A ++ +L++ + +EK+ ++KG +
Sbjct: 940 SAYGSSIQALREQAQSCRQQ---VAPMDDETGKELVLALYDYQEKSpreVTMKKGDILTL 996
Query: 343 -----EDSHNYQLFDRDADEIKAWI--VEKLKTASDENYKEPTNLQSKVQKHQNFLAEIA 501
+D ++ DR A++ ++ ++AS EN E IA
Sbjct: 997 LNSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSASRENLLEEQG-------------SIA 1043
Query: 502 ANEGRIDDVKSRGQSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQ 681
+G+ID+ Q+ + + + + R++++++L++ L+ + ++ L ++ +
Sbjct: 1044 LRQGQIDN-----QTRITKE---AGSVSLRMKQVEELYQSLLELGEKRKGMLEKSCKKFM 1095
Query: 682 FIRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQAD 861
R +++ W+ E E+ L S++ G DL V LQKK + + D+ +++ R+ + A+
Sbjct: 1096 LFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAE 1155
Query: 862 QFVHDNHF--DADAIKKKQI----------------------------------EVCNRY 933
+ + A++++++ E+ R+
Sbjct: 1156 DLESEGLMAEEVQAVQQQEVYGMMPRDEADSKTASPWKSARLMVHTVATFNSIKELNERW 1215
Query: 934 SKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKH 1113
LQ+ E+R L A+++ +F+RDAD+ ++WI EK + N G DL VQ L +KH
Sbjct: 1216 RSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKH 1275
Query: 1114 QAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLL 1293
+ + ++ ++ + Q++I + + D+++K ++ W+ L +AD+R+ L
Sbjct: 1276 EGFERDLAALGDKVNSLGETAQRLIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKL 1335
Query: 1294 DDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRSTI 1473
DS + Q++L+D + SW+ LV S E KD EALL++H +I+A T
Sbjct: 1336 GDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTF 1395
Query: 1474 DS 1479
+
Sbjct: 1396 QA 1397
Score = 163 bits (413), Expect = 1e-39
Identities = 95/319 (29%), Positives = 171/319 (53%)
Frame = +1
Query: 571 SDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDD 750
++DIQ+R +++ + S ++ L + Q F R+ E++E W+ E + Q+ SD+
Sbjct: 12 AEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQE-KLQVASDE 70
Query: 751 CGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNR 930
KD ++ +KH E+++ ++ I + + + + HF ++ I+ + +E+ +
Sbjct: 71 NYKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLMELHRQ 130
Query: 931 YSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKK 1110
+ L E + ++ KL A KL Q+ R+ +D DWI++KE I S +G+DL V+ L KK
Sbjct: 131 WELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKK 190
Query: 1111 HQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQL 1290
+ Q ++ HE R+ EV K+I H I+ K +++ W LK A +R+
Sbjct: 191 FEEFQTDLAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQEEVNAAWQRLKGLALQRQGK 250
Query: 1291 LDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRST 1470
L + E Q++ D E W++EKE L+ S +FG+D S +ALL+KH+ L D+ A
Sbjct: 251 LFGAAEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAALEDK 310
Query: 1471 IDSLRTQADACKMQEAPVS 1527
+ +L +AD + Q P+S
Sbjct: 311 VKALCAEADRLQ-QSHPLS 328
>sp|P13395|SPTCA_DROME Spectrin alpha chain Length = 2415 Score = 735 bits (1898), Expect = 0.0 Identities = 358/627 (57%), Positives = 474/627 (75%) Frame = +1 Query: 1 WNERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKS 180 W +RR LYEQ MDLQLFYRDTEQA+ W+AKQEAFL N D+GDSLDSVEALI+KHEDFEKS Sbjct: 459 WEDRRILYEQCMDLQLFYRDTEQADTWMAKQEAFLANEDLGDSLDSVEALIKKHEDFEKS 518 Query: 181 LAAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNY 360 LAAQEEK + LD A KL++ HYAA DV ++R LL R+A L+EK+ R+ LEDS+ Y Sbjct: 519 LAAQEEKIKALDIFATKLIDGQHYAADDVAQRRQMLLARRAALQEKSSKRRQLLEDSNRY 578 Query: 361 QLFDRDADEIKAWIVEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRG 540 Q F+RD DE K WI EKLK A+D++Y +PTNL K+QKHQNF E+ AN+ RI+D+ + G Sbjct: 579 QQFERDCDETKGWISEKLKFATDDSYLDPTNLNGKMQKHQNFEHELNANKSRIEDITNVG 638 Query: 541 QSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLA 720 L++ H +D I R++E+ LW+ LV AS K T L +A QQQF R +ED+E+WL+ Sbjct: 639 TELIEKQHYAADQINTRMQEIVVLWETLVQASDKKGTKLNEACQQQQFNRTIEDIELWLS 698 Query: 721 EVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAI 900 E+E QL S+D GKDL SV NLQKKH LLE+D+ +HQDRI+S A++F+ HFDAD I Sbjct: 699 EIEGQLLSEDHGKDLTSVQNLQKKHALLEADVMAHQDRIESIKVAANKFIESGHFDADNI 758 Query: 901 KKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRD 1080 + K+ + RY+ L P+ +RK L D+ ++ Q +RD +DE WI EKEPIA STN GRD Sbjct: 759 RNKEGNLSARYAALAAPMGERKQHLLDSLQVQQLFRDLEDEAAWIREKEPIAASTNRGRD 818 Query: 1081 LIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDL 1260 LIGVQNLIKKHQA+ AE+ HE R+L V + G+ M+ +A+ DI ++++ ++ W+ L Sbjct: 819 LIGVQNLIKKHQAVLAEINNHEARLLNVISSGENMLKDQPFASDDIRQRLEALQEQWNTL 878 Query: 1261 KNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDAL 1440 K K+ +R+Q LDDSL+A QY ADA+EAESWMREKEP+ +++GKDEDS+EALLKKH+AL Sbjct: 879 KEKSSQRKQDLDDSLQAHQYFADANEAESWMREKEPIATGSDYGKDEDSSEALLKKHEAL 938 Query: 1441 MADIEAYRSTIDSLRTQADACKMQEAPVSDSYGKETVMALYDYQEKNpreVSMRKGDVLT 1620 ++D+EA+ +TI +L+ QA C+ QE PV D GKE V+ALYDY EK+preVSM+KGDVLT Sbjct: 939 VSDLEAFGNTIQALQEQAKNCRQQETPVVDITGKECVVALYDYTEKSpreVSMKKGDVLT 998 Query: 1621 LLNSNHKDWWKVEINDRQGHVPAAYVKKVDAMMSDIDPNAPEQITVASQQKNLENQYENL 1800 LLNSN+KDWWKVE+NDRQG VPAAY+KK+DA +S N + ++A +Q + +QY+NL Sbjct: 999 LLNSNNKDWWKVEVNDRQGFVPAAYIKKIDAGLSASQQNLVDNHSIAKRQNQINSQYDNL 1058 Query: 1801 LSLGKDRRDRLKDSVQAYQLVREANDL 1881 L+L ++R+++L ++V+AY LVREA DL Sbjct: 1059 LALARERQNKLNETVKAYVLVREAADL 1085
Score = 412 bits (1059), Expect = e-114
Identities = 211/490 (43%), Positives = 310/490 (63%), Gaps = 2/490 (0%)
Frame = +1
Query: 1 WNERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKS 180
W ERR EQN+DLQL+ RD E AE+W++ +EAFL +D ++ +VEALI+KHEDF+K+
Sbjct: 1382 WTERRLQLEQNLDLQLYMRDCELAESWMSAREAFLNADDDANAGGNVEALIKKHEDFDKA 1441
Query: 181 LAAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNY 360
+ E+K L +A++L+ HYA+ V++KR +L R +L+E ++ L D
Sbjct: 1442 INGHEQKIAALQTVADQLIAQNHYASNLVDEKRKQVLERWRHLKEGLIEKRSRLGDEQTL 1501
Query: 361 QLFDRDADEIKAWIVEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRG 540
Q F RDADEI+ WI EKL+ A++E+YK+P N+QSK QKHQ F AE+AAN RI V + G
Sbjct: 1502 QQFSRDADEIENWIAEKLQLATEESYKDPANIQSKHQKHQAFEAELAANADRIQSVLAMG 1561
Query: 541 QSLLDSDH--NKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIW 714
+L+D D +Q+R+ ++ W+ L + K L +A+ Q+ +I V+D++ W
Sbjct: 1562 GNLIDKKQCSGSEDAVQKRLTQIADQWEYLTHKTTEKSLKLKEANKQRTYIAAVKDLDFW 1621
Query: 715 LAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDAD 894
L EVES L ++D GKDL SV NL KKH L+E+DI +H+DRI QAD V FD
Sbjct: 1622 LGEVESLLTTEDSGKDLASVQNLMKKHQLVEADIVAHEDRIKDMNNQADSLVESGQFDTA 1681
Query: 895 AIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVG 1074
I++K+ + RY ++ R+ +LN+A LHQF+RD DEE WI EK+ + GS + G
Sbjct: 1682 GIQEKRQSINERYERICNLAAHRQARLNEALTLHQFFRDIADEESWIKEKKLLVGSDDYG 1741
Query: 1075 RDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWS 1254
RDL GVQNL KKH+ ++AE+ HEP I V G+K++D ++ +IE+++ + W+
Sbjct: 1742 RDLTGVQNLKKKHKRLEAELGSHEPAIQAVQEAGEKLMDVSNLGVPEIEQRLKALNQAWA 1801
Query: 1255 DLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHD 1434
+LKN A R Q LD+SL QQ+LA E E+W+ EK+ L+ ++G + + LLKKHD
Sbjct: 1802 ELKNLAATRGQKLDESLTYQQFLAQVEEEEAWITEKQQLLSVEDYGDSMAAVQGLLKKHD 1861
Query: 1435 ALMADIEAYR 1464
A D A++
Sbjct: 1862 AFETDFTAHK 1871
Score = 269 bits (688), Expect = 2e-71
Identities = 146/444 (32%), Positives = 258/444 (58%), Gaps = 9/444 (2%)
Frame = +1
Query: 262 DVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWIVEKLKTASDENYK 441
D+ ++R+ +L R + + + + ++ LEDS +Q F RDADE+++WI EKL+ AS+E+Y+
Sbjct: 17 DIQERREQVLSRYNDFKIETRQKREKLEDSRRFQYFKRDADELESWIHEKLQAASEESYR 76
Query: 442 EPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNKSDDIQQRIEELDKLWKD 621
+PTNLQ+K+QKHQ F AE++A+ I + + GQ +++ H S+ IQ R++EL KLW+
Sbjct: 77 DPTNLQAKIQKHQAFEAEVSAHSNAIVSLDNTGQEMINQQHFASESIQVRLDELHKLWEL 136
Query: 622 LVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKKHNL 801
L+S K L QA QF+R E++ W+ + E+ + +D+ G+DL V LQ+K +
Sbjct: 137 LLSRLAEKGLKLQQALVLVQFLRQCEEVMFWIKDKETFVTADEFGQDLEHVEVLQRKFDE 196
Query: 802 LESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNRYSKLQEPLEKRKNKLND 981
+ D++S + R+ Q AD+ V D H + D I K++ E+ + +L++ R+ KL
Sbjct: 197 FQKDMASQEYRVTEVNQLADKLVQDGHPERDTITKRKEELNEAWQRLKQLAIVRQEKLFG 256
Query: 982 AYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKHQAIQAEVTGHEPRILE 1161
A+++ +F RDAD+ WI EK+ + S + GRDL VQ L +KH+ ++ ++ E ++
Sbjct: 257 AHEIQRFNRDADETVAWIAEKDVVLSSDDYGRDLASVQALQRKHEGVERDLAALEDKVST 316
Query: 1162 VCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLLDDSLEAQQYLADASEA 1341
+ E Q++ + + I K ++ N W L KA +R+Q LD+S ++LAD +
Sbjct: 317 LGAEAQRLCSIHADHSDQIRDKQAEIANYWQSLTTKARERKQKLDESYYLHRFLADFRDL 376
Query: 1342 ESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEA----YRSTIDS-----LRTQA 1494
SW+ + ++ + E KD EALL++H +I+A ++ T +S R
Sbjct: 377 VSWINGMKAIISADELAKDVAGAEALLERHQEHKGEIDAREDSFKLTTESGQKLLEREHY 436
Query: 1495 DACKMQEAPVSDSYGKETVMALYD 1566
A ++QE + K ++++L++
Sbjct: 437 AAAEIQEKLAALENDKSSLLSLWE 460
Score = 233 bits (595), Expect = 1e-60
Identities = 168/664 (25%), Positives = 310/664 (46%), Gaps = 40/664 (6%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
E+ +Q + L F R E+ WI +E F+ ++ G L+ VE L RK ++F+K +A
Sbjct: 143 EKGLKLQQALVLVQFLRQCEEVMFWIKDKETFVTADEFGQDLEHVEVLQRKFDEFQKDMA 202
Query: 187 AQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQL 366
+QE + ++ +A+KLV++GH + K++++L L++ A +R+ L +H Q
Sbjct: 203 SQEYRVTEVNQLADKLVQDGHPERDTITKRKEELNEAWQRLKQLAIVRQEKLFGAHEIQR 262
Query: 367 FDRDADEIKAWIVEKLKTASDENY-KEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQ 543
F+RDADE AWI EK S ++Y ++ ++Q+ +KH+ ++AA E ++ + + Q
Sbjct: 263 FNRDADETVAWIAEKDVVLSSDDYGRDLASVQALQRKHEGVERDLAALEDKVSTLGAEAQ 322
Query: 544 SLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAE 723
L + SD I+ + E+ W+ L + ++ ++ L ++ +F+ + D+ W+
Sbjct: 323 RLCSIHADHSDQIRDKQAEIANYWQSLTTKARERKQKLDESYYLHRFLADFRDLVSWING 382
Query: 724 VESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIK 903
+++ + +D+ KD+ L ++H + +I + +D + + + H+ A I+
Sbjct: 383 MKAIISADELAKDVAGAEALLERHQEHKGEIDAREDSFKLTTESGQKLLEREHYAAAEIQ 442
Query: 904 KKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDL 1083
+K + N S L E R+ L FYRD + + W+ ++E + ++G L
Sbjct: 443 EKLAALENDKSSLLSLWEDRRILYEQCMDLQLFYRDTEQADTWMAKQEAFLANEDLGDSL 502
Query: 1084 IGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLK 1263
V+ LIKKH+ + + E +I + K+IDG HYA D+ ++ + + L+
Sbjct: 503 DSVEALIKKHEDFEKSLAAQEEKIKALDIFATKLIDGQHYAADDVAQRRQMLLARRAALQ 562
Query: 1264 NKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALM 1443
K+ KRRQLL+DS QQ+ D E + W+ EK + D + ++KH
Sbjct: 563 EKSSKRRQLLEDSNRYQQFERDCDETKGWISEKLKFATDDSY-LDPTNLNGKMQKHQNFE 621
Query: 1444 ADIEAYRSTIDSLRT-----------QADA--CKMQEAPV--------SDSYGKETVMAL 1560
++ A +S I+ + AD +MQE V SD G + A
Sbjct: 622 HELNANKSRIEDITNVGTELIEKQHYAADQINTRMQEIVVLWETLVQASDKKGTKLNEAC 681
Query: 1561 YDYQ-------------EKNpreVSMRKGDVLTLLNSNHKDWWKVEIN-----DRQGHVP 1686
Q E + +S G LT + + K +E + DR +
Sbjct: 682 QQQQFNRTIEDIELWLSEIEGQLLSEDHGKDLTSVQNLQKKHALLEADVMAHQDRIESIK 741
Query: 1687 AAYVKKVDAMMSDIDPNAPEQITVASQQKNLENQYENLLSLGKDRRDRLKDSVQAYQLVR 1866
A K +++ D D + +++ NL +Y L + +R+ L DS+Q QL R
Sbjct: 742 VAANKFIESGHFDAD-------NIRNKEGNLSARYAALAAPMGERKQHLLDSLQVQQLFR 794
Query: 1867 EAND 1878
+ D
Sbjct: 795 DLED 798
Score = 233 bits (594), Expect = 1e-60
Identities = 135/495 (27%), Positives = 256/495 (51%), Gaps = 3/495 (0%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
++R E + Q F RD ++ E+WI ++ D + ++A I+KH+ FE ++
Sbjct: 38 QKREKLEDSRRFQYFKRDADELESWIHEKLQAASEESYRDPTN-LQAKIQKHQAFEAEVS 96
Query: 187 AQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQL 366
A LD+ +++ H+A+ + + D+L L + + L+ +
Sbjct: 97 AHSNAIVSLDNTGQEMINQQHFASESIQVRLDELHKLWELLLSRLAEKGLKLQQALVLVQ 156
Query: 367 FDRDADEIKAWIVEKLK-TASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQ 543
F R +E+ WI +K +DE ++ +++ +K F ++A+ E R+ +V
Sbjct: 157 FLRQCEEVMFWIKDKETFVTADEFGQDLEHVEVLQRKFDEFQKDMASQEYRVTEVNQLAD 216
Query: 544 SLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAE 723
L+ H + D I +R EEL++ W+ L + +++ L A Q+F R+ ++ W+AE
Sbjct: 217 KLVQDGHPERDTITKRKEELNEAWQRLKQLAIVRQEKLFGAHEIQRFNRDADETVAWIAE 276
Query: 724 VESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQF--VHDNHFDADA 897
+ L SDD G+DL SV LQ+KH +E D+++ +D++ + +A + +H +H +D
Sbjct: 277 KDVVLSSDDYGRDLASVQALQRKHEGVERDLAALEDKVSTLGAEAQRLCSIHADH--SDQ 334
Query: 898 IKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGR 1077
I+ KQ E+ N + L +RK KL+++Y LH+F D D WI+ + I + + +
Sbjct: 335 IRDKQAEIANYWQSLTTKARERKQKLDESYYLHRFLADFRDLVSWINGMKAIISADELAK 394
Query: 1078 DLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSD 1257
D+ G + L+++HQ + E+ E GQK+++ HYA +I++K+ ++N S
Sbjct: 395 DVAGAEALLERHQEHKGEIDAREDSFKLTTESGQKLLEREHYAAAEIQEKLAALENDKSS 454
Query: 1258 LKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDA 1437
L + + RR L + ++ Q + D +A++WM ++E + + + G DS EAL+KKH+
Sbjct: 455 LLSLWEDRRILYEQCMDLQLFYRDTEQADTWMAKQEAFLANEDLGDSLDSVEALIKKHED 514
Query: 1438 LMADIEAYRSTIDSL 1482
+ A I +L
Sbjct: 515 FEKSLAAQEEKIKAL 529
Score = 230 bits (586), Expect = 1e-59
Identities = 123/486 (25%), Positives = 260/486 (53%), Gaps = 3/486 (0%)
Frame = +1
Query: 37 DLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQRLD 216
DLQ F D AWI + + ++++ + + EALI +H++ + A+ +
Sbjct: 1288 DLQRFLSDYRDLLAWINSMMSLVTSDELANDVTGAEALIERHQEHRTEIDARAGTFGAFE 1347
Query: 217 DIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKA 396
N+L++ HYA+ ++ +K +DL + +LE+ R+ LE + + QL+ RD + ++
Sbjct: 1348 QFGNELLQANHYASPEIKEKIEDLAKAREDLEKAWTERRLQLEQNLDLQLYMRDCELAES 1407
Query: 397 WI-VEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNKS 573
W+ + +D++ N+++ ++KH++F I +E +I +++ L+ +H S
Sbjct: 1408 WMSAREAFLNADDDANAGGNVEALIKKHEDFDKAINGHEQKIAALQTVADQLIAQNHYAS 1467
Query: 574 DDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDC 753
+ + ++ +++ + W+ L K + L QQF R+ +++E W+AE + QL +++
Sbjct: 1468 NLVDEKRKQVLERWRHLKEGLIEKRSRLGDEQTLQQFSRDADEIENWIAE-KLQLATEES 1526
Query: 754 GKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDA--DAIKKKQIEVCN 927
KD ++ + +KH E++++++ DRI S L + DA++K+ ++ +
Sbjct: 1527 YKDPANIQSKHQKHQAFEAELAANADRIQSVLAMGGNLIDKKQCSGSEDAVQKRLTQIAD 1586
Query: 928 RYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIK 1107
++ L ++ KL +A K + D + W+ E E + + + G+DL VQNL+K
Sbjct: 1587 QWEYLTHKTTEKSLKLKEANKQRTYIAAVKDLDFWLGEVESLLTTEDSGKDLASVQNLMK 1646
Query: 1108 KHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQ 1287
KHQ ++A++ HE RI ++ N+ +++ + I++K + + + N A R+
Sbjct: 1647 KHQLVEADIVAHEDRIKDMNNQADSLVESGQFDTAGIQEKRQSINERYERICNLAAHRQA 1706
Query: 1288 LLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRS 1467
L+++L Q+ D ++ ESW++EK+ LVGS ++G+D + L KKH L A++ ++
Sbjct: 1707 RLNEALTLHQFFRDIADEESWIKEKKLLVGSDDYGRDLTGVQNLKKKHKRLEAELGSHEP 1766
Query: 1468 TIDSLR 1485
I +++
Sbjct: 1767 AIQAVQ 1772
Score = 219 bits (558), Expect = 2e-56
Identities = 126/489 (25%), Positives = 253/489 (51%), Gaps = 4/489 (0%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
E+R LQ F RD ++ E WIA++ D + +++ +KH+ FE LA
Sbjct: 1490 EKRSRLGDEQTLQQFSRDADEIENWIAEKLQLATEESYKDPAN-IQSKHQKHQAFEAELA 1548
Query: 187 AQEEKTQRLDDIANKLVENGHYAAAD--VNKKRDDLLIRKANLEEKAKLRKGSLEDSHNY 360
A ++ Q + + L++ + ++ V K+ + + L K + L++++
Sbjct: 1549 ANADRIQSVLAMGGNLIDKKQCSGSEDAVQKRLTQIADQWEYLTHKTTEKSLKLKEANKQ 1608
Query: 361 QLFDRDADEIKAWI--VEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKS 534
+ + ++ W+ VE L T D K+ ++Q+ ++KHQ A+I A+E RI D+ +
Sbjct: 1609 RTYIAAVKDLDFWLGEVESLLTTEDSG-KDLASVQNLMKKHQLVEADIVAHEDRIKDMNN 1667
Query: 535 RGQSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIW 714
+ SL++S + IQ++ + +++ ++ + + + ++ L +A QF R++ D E W
Sbjct: 1668 QADSLVESGQFDTAGIQEKRQSINERYERICNLAAHRQARLNEALTLHQFFRDIADEESW 1727
Query: 715 LAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDAD 894
+ E + +GSDD G+DL V NL+KKH LE+++ SH+ I + + ++ + ++
Sbjct: 1728 IKEKKLLVGSDDYGRDLTGVQNLKKKHKRLEAELGSHEPAIQAVQEAGEKLMDVSNLGVP 1787
Query: 895 AIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVG 1074
I+++ + +++L+ R KL+++ QF ++EE WI EK+ + + G
Sbjct: 1788 EIEQRLKALNQAWAELKNLAATRGQKLDESLTYQQFLAQVEEEEAWITEKQQLLSVEDYG 1847
Query: 1075 RDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWS 1254
+ VQ L+KKH A + + T H+ R +C++G ++++ ++ I ++ ++
Sbjct: 1848 DSMAAVQGLLKKHDAFETDFTAHKDRCSLICDQGSELVEAKNHHGESIAQRCQQLRLKLD 1907
Query: 1255 DLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHD 1434
+L A +R+ L D+ Q++ A ESW+ +KE V S EFG+D + + LL K +
Sbjct: 1908 NLSALAARRKGALLDNSAYLQFMWKADVVESWIDDKENYVRSDEFGRDLSTVQTLLTKQE 1967
Query: 1435 ALMADIEAY 1461
A + A+
Sbjct: 1968 TFDAGLNAF 1976
Score = 202 bits (515), Expect = 2e-51
Identities = 149/661 (22%), Positives = 299/661 (45%), Gaps = 37/661 (5%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDV-GDSLDSVEALIRKHEDFEKSL 183
ER+ + + + R+ WI +E + DV G+ L+ VE L +K +DF L
Sbjct: 1064 ERQNKLNETVKAYVLVREAADLAQWIRDKENHAQIADVVGEDLEEVEVLQKKFDDFNDDL 1123
Query: 184 AAQEEKTQRLDDIANKLVENGHYAAA-DVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNY 360
A E + +++IA +L G AA + + DL + NL+ + L +H
Sbjct: 1124 KANEVRLANMNEIAVQLTSLGQTEAALKIQTQMQDLNEKWNNLQTLTAEKASQLGSAHEV 1183
Query: 361 QLFDRDADEIKAWIVEKLKTASDENY-KEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSR 537
Q F RD DE K WI EK ++++ K+ ++Q+ +KH+ ++AA +I +
Sbjct: 1184 QRFHRDIDETKDWIAEKANALNNDDLGKDLRSVQTLQRKHEGVERDLAALRDKIRQLDET 1243
Query: 538 GQSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWL 717
L+ S + ++ + +E++++W +++ S ++ L + Q+F+ + D+ W+
Sbjct: 1244 ANRLMQSHPDTAEQTYAKQKEINEMWDQIITKSTARKEKLLDSYDLQRFLSDYRDLLAWI 1303
Query: 718 AEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADA 897
+ S + SD+ D+ L ++H ++I + +F Q ++ + NH+ +
Sbjct: 1304 NSMMSLVTSDELANDVTGAEALIERHQEHRTEIDARAGTFGAFEQFGNELLQANHYASPE 1363
Query: 898 IKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGR 1077
IK+K ++ L++ +R+ +L L + RD + E W+ +E + +
Sbjct: 1364 IKEKIEDLAKAREDLEKAWTERRLQLEQNLDLQLYMRDCELAESWMSAREAFLNADDDAN 1423
Query: 1078 DLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSD 1257
V+ LIKKH+ + GHE +I + ++I NHYA+ +++K + W
Sbjct: 1424 AGGNVEALIKKHEDFDKAINGHEQKIAALQTVADQLIAQNHYASNLVDEKRKQVLERWRH 1483
Query: 1258 LKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDA 1437
LK ++R L D QQ+ DA E E+W+ EK L + E KD + ++ +KH A
Sbjct: 1484 LKEGLIEKRSRLGDEQTLQQFSRDADEIENWIAEKLQL-ATEESYKDPANIQSKHQKHQA 1542
Query: 1438 LMADIEAYRSTIDSLRTQA-------------DACKMQEAPVSDSY---GKETVMALYDY 1569
A++ A I S+ DA + + ++D + +T
Sbjct: 1543 FEAELAANADRIQSVLAMGGNLIDKKQCSGSEDAVQKRLTQIADQWEYLTHKTTEKSLKL 1602
Query: 1570 QEKNP--------REVSMRKGDVLTLLNS--NHKDWWKVEINDRQGHVPAAYVKKVDAMM 1719
+E N +++ G+V +LL + + KD V+ ++ + A + + +
Sbjct: 1603 KEANKQRTYIAAVKDLDFWLGEVESLLTTEDSGKDLASVQNLMKKHQLVEADIVAHEDRI 1662
Query: 1720 SDIDPNAPEQIT--------VASQQKNLENQYENLLSLGKDRRDRLKDSVQAYQLVREAN 1875
D++ A + + +++++ +YE + +L R+ RL +++ +Q R+
Sbjct: 1663 KDMNNQADSLVESGQFDTAGIQEKRQSINERYERICNLAAHRQARLNEALTLHQFFRDIA 1722
Query: 1876 D 1878
D
Sbjct: 1723 D 1723
Score = 191 bits (485), Expect = 6e-48
Identities = 131/503 (26%), Positives = 238/503 (47%), Gaps = 2/503 (0%)
Frame = +1
Query: 79 WIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQRLDDIANKLVENGHYAA 258
W+ + E+ L D G L SV+ L++KH+ E + A E++ + +++ A+ LVE+G +
Sbjct: 1621 WLGEVESLLTTEDSGKDLASVQNLMKKHQLVEADIVAHEDRIKDMNNQADSLVESGQFDT 1680
Query: 259 ADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWIVEK-LKTASDEN 435
A + +KR + R + A R+ L ++ F RD + ++WI EK L SD+
Sbjct: 1681 AGIQEKRQSINERYERICNLAAHRQARLNEALTLHQFFRDIADEESWIKEKKLLVGSDDY 1740
Query: 436 YKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNKSDDIQQRIEELDKLW 615
++ T +Q+ +KH+ AE+ ++E I V+ G+ L+D + +I+QR++ L++ W
Sbjct: 1741 GRDLTGVQNLKKKHKRLEAELGSHEPAIQAVQEAGEKLMDVSNLGVPEIEQRLKALNQAW 1800
Query: 616 KDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKKH 795
+L + + + L ++ QQF+ VE+ E W+ E + L +D G + +V L KKH
Sbjct: 1801 AELKNLAATRGQKLDESLTYQQFLAQVEEEEAWITEKQQLLSVEDYGDSMAAVQGLLKKH 1860
Query: 796 NLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNRYSKLQEPLEKRKNKL 975
+ E+D ++H+DR Q + V + ++I ++ ++ + L +RK L
Sbjct: 1861 DAFETDFTAHKDRCSLICDQGSELVEAKNHHGESIAQRCQQLRLKLDNLSALAARRKGAL 1920
Query: 976 NDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKHQAIQAEVTGHEPR- 1152
D QF AD E WI +KE S GRDL VQ L+ K + A + E
Sbjct: 1921 LDNSAYLQFMWKADVVESWIDDKENYVRSDEFGRDLSTVQTLLTKQETFDAGLNAFEQEG 1980
Query: 1153 ILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLLDDSLEAQQYLADA 1332
I + ++I+ +H + I K+ D+ W L++ ++ R+ D L Q+
Sbjct: 1981 IHNITALKDQLINASHAQSPAILKRHGDVIARWQKLRDASNTRK---DRLLAMQEQFRQI 2037
Query: 1333 SEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRSTIDSLRTQADACKMQ 1512
E +K S +ED T+ + ++I+ +R DA
Sbjct: 2038 EELYLTFAKKASAFNSWFENAEEDLTDPV-------------RCNSIEEIRALRDAHAQF 2084
Query: 1513 EAPVSDSYGKETVMALYDYQEKN 1581
+A +S + +A D + K+
Sbjct: 2085 QASLSSAEADFKALAALDQKIKS 2107
Score = 151 bits (382), Expect = 6e-36
Identities = 123/522 (23%), Positives = 235/522 (45%), Gaps = 9/522 (1%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
ER+ ++ +Q +RD E AWI ++E + + G L V+ LI+KH+ +
Sbjct: 778 ERKQHLLDSLQVQQLFRDLEDEAAWIREKEPIAASTNRGRDLIGVQNLIKKHQAVLAEIN 837
Query: 187 AQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQL 366
E + + ++++ +A+ D+ ++ + L + L+EK+ RK L+DS
Sbjct: 838 NHEARLLNVISSGENMLKDQPFASDDIRQRLEALQEQWNTLKEKSSQRKQDLDDSLQAHQ 897
Query: 367 FDRDADEIKAWIVEKLKTASDENY-KEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQ 543
+ DA+E ++W+ EK A+ +Y K+ + ++ ++KH E + D+++ G
Sbjct: 898 YFADANEAESWMREKEPIATGSDYGKDEDSSEALLKKH----------EALVSDLEAFGN 947
Query: 544 SLLDSDHNKSDDIQQRIEELDKLWKDLVSA----SKIKETNLTQASGQQQFIRNVEDMEI 711
++ + QQ +D K+ V A ++ ++ G + N + +
Sbjct: 948 TIQALQEQAKNCRQQETPVVDITGKECVVALYDYTEKSpreVSMKKGDVLTLLNSNNKDW 1007
Query: 712 WLAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDA 891
W EV + G +++ +ID+ L + Q + DNH
Sbjct: 1008 WKVEVNDRQGFVP----------------------AAYIKKIDAGLSASQQNLVDNH--- 1042
Query: 892 DAIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTN- 1068
+I K+Q ++ ++Y L +R+NKLN+ K + R+A D WI +KE A +
Sbjct: 1043 -SIAKRQNQINSQYDNLLALARERQNKLNETVKAYVLVREAADLAQWIRDKENHAQIADV 1101
Query: 1069 VGRDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMID-GNHYANRDIEKKIDDMKN 1245
VG DL V+ L KK ++ +E R+ + ++ G A I+ ++ D+
Sbjct: 1102 VGEDLEEVEVLQKKFDDFNDDLKANEVRLANMNEIAVQLTSLGQTEAALKIQTQMQDLNE 1161
Query: 1246 LWSDLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLK 1425
W++L+ ++ L + E Q++ D E + W+ EK + + + GKD S + L +
Sbjct: 1162 KWNNLQTLTAEKASQLGSAHEVQRFHRDIDETKDWIAEKANALNNDDLGKDLRSVQTLQR 1221
Query: 1426 KHDALMADIEAYRSTIDSLRTQADACKMQEAP--VSDSYGKE 1545
KH+ + D+ A R I L A+ MQ P +Y K+
Sbjct: 1222 KHEGVERDLAALRDKIRQLDETANRL-MQSHPDTAEQTYAKQ 1262
Score = 142 bits (359), Expect = 3e-33
Identities = 85/319 (26%), Positives = 159/319 (49%)
Frame = +1
Query: 574 DDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDC 753
+DIQ+R E++ + D ++ K L + Q F R+ +++E W+ E + Q S++
Sbjct: 16 EDIQERREQVLSRYNDFKIETRQKREKLEDSRRFQYFKRDADELESWIHE-KLQAASEES 74
Query: 754 GKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNRY 933
+D ++ +KH E+++S+H + I S + ++ HF +++I+ + E+ +
Sbjct: 75 YRDPTNLQAKIQKHQAFEAEVSAHSNAIVSLDNTGQEMINQQHFASESIQVRLDELHKLW 134
Query: 934 SKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKH 1113
L L ++ KL A L QF R ++ WI +KE + G+DL V+ L +K
Sbjct: 135 ELLLSRLAEKGLKLQQALVLVQFLRQCEEVMFWIKDKETFVTADEFGQDLEHVEVLQRKF 194
Query: 1114 QAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLL 1293
Q ++ E R+ EV K++ H I K+ +++ W LK A R++ L
Sbjct: 195 DEFQKDMASQEYRVTEVNQLADKLVQDGHPERDTITKRKEELNEAWQRLKQLAIVRQEKL 254
Query: 1294 DDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRSTI 1473
+ E Q++ DA E +W+ EK+ ++ S ++G+D S +AL +KH+ + D+ A +
Sbjct: 255 FGAHEIQRFNRDADETVAWIAEKDVVLSSDDYGRDLASVQALQRKHEGVERDLAALEDKV 314
Query: 1474 DSLRTQADACKMQEAPVSD 1530
+L +A A SD
Sbjct: 315 STLGAEAQRLCSIHADHSD 333
>sp|P02549|SPTA1_HUMAN Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin) Length = 2418 Score = 535 bits (1379), Expect = e-151 Identities = 273/633 (43%), Positives = 406/633 (64%), Gaps = 6/633 (0%) Frame = +1 Query: 1 WNERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKS 180 W+ER YEQ +D LFYRD+EQ ++W+++QEAFLEN D+G+SL S EAL++KHEDFE++ Sbjct: 465 WDERHRQYEQCLDFHLFYRDSEQVDSWMSRQEAFLENEDLGNSLGSAEALLQKHEDFEEA 524 Query: 181 LAAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNY 360 AQEEK +D A KL+ + HY + ++ RD LL R+ L EKA R+ L++S Sbjct: 525 FTAQEEKIITVDKTATKLIGDDHYDSENIKAIRDGLLARRDALREKAATRRRLLKESLLL 584 Query: 361 QLFDRDADEIKAWIVEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRG 540 Q D+D++K WI +K K A DE+YK+ NL+S+VQK Q F E+A N+ ++++++ G Sbjct: 585 QKLYEDSDDLKNWINKKKKLADDEDYKDIQNLKSRVQKQQVFEKELAVNKTQLENIQKTG 644 Query: 541 QSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLA 720 Q +++ H SD++ R+ E+ LW++L+ A+K K T L +A+ Q QF N ED++ WL Sbjct: 645 QEMIEGGHYASDNVTTRLSEVASLWEELLEATKQKGTQLHEANQQLQFENNAEDLQRWLE 704 Query: 721 EVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAI 900 +VE Q+ S+D GK L V N +KH LLES +++ QD++D A F H D+ I Sbjct: 705 DVEWQVTSEDYGKGLAEVQNRLRKHGLLESAVAARQDQVDILTDLAAYFEEIGHPDSKDI 764 Query: 901 KKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRD 1080 + +Q + R+ L+EPL RK KL D L RD +DEE WI E EP A ST +G+D Sbjct: 765 RARQESLVCRFEALKEPLATRKKKLLDLLHLQLICRDTEDEEAWIQETEPSATSTYLGKD 824 Query: 1081 LIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDL 1260 LI + L+ +H+ I + HEPRI E+ G KM++ H+A D+ ++ + L Sbjct: 825 LIASKKLLNRHRVILENIASHEPRIQEITERGNKMVEEGHFAAEDVASRVKSLNQNMESL 884 Query: 1261 KNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDAL 1440 + +A +R+ L+ +++ QQYLAD EAE+W+REKEP+V +T +G DE++ ALLKKH+A Sbjct: 885 RARAARRQNDLEANVQFQQYLADLHEAETWIREKEPIVDNTNYGADEEAAGALLKKHEAF 944 Query: 1441 MADIEAYRSTIDSLRTQADACKMQE-APVSDSYGKETVMALYDYQEKNpreVSMRKGDVL 1617 + D+ ++ ++ +LR QA+AC+ Q+ APV G++ VMALYD+Q ++preV+M+KGDVL Sbjct: 945 LLDLNSFGDSMKALRNQANACQQQQAAPVEGVAGEQRVMALYDFQARSpreVTMKKGDVL 1004 Query: 1618 TLLNSNHKDWWKVEINDRQGHVPAAYVKKVDAMMSDIDPNAP-----EQITVASQQKNLE 1782 TLL+S +KDWWKVE D QG VPA YV++ + D P P E + +Q+ +E Sbjct: 1005 TLLSSINKDWWKVEAADHQGIVPAVYVRR---LAHDEFPMLPQRRREEPGNITQRQEQIE 1061 Query: 1783 NQYENLLSLGKDRRDRLKDSVQAYQLVREANDL 1881 NQY +LL ++RR RL + L EA D+ Sbjct: 1062 NQYRSLLDRAEERRRRLLQRYNEFLLAYEAGDM 1094
Score = 311 bits (796), Expect = 5e-84
Identities = 176/529 (33%), Positives = 289/529 (54%), Gaps = 1/529 (0%)
Frame = +1
Query: 1 WNERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKS 180
W +R+ + +Q ++LQ+F + +Q E+ + +E L ++D SLDS+EAL++K +D +K+
Sbjct: 1384 WEKRKKILDQCLELQMFQGNCDQVESRMVARENSLRSDDKS-SLDSLEALMKKRDDLDKA 1442
Query: 181 LAAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNY 360
+ AQE K L+ A L+ + HYA ++ + +L R L+ + + L D N
Sbjct: 1443 ITAQEGKITDLEHFAESLIADEHYAKEEIATRLQRVLDRWKALKAQLIDERTKLGDYANL 1502
Query: 361 QLFDRDADEIKAWIVEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRG 540
+ F RD +E++ WI E L TA DE+YK+ TN+Q K KHQ F E+ ++ V + G
Sbjct: 1503 KQFYRDLEELEEWISEMLPTACDESYKDATNIQRKYLKHQTFAHEVDGRSEQVHGVINLG 1562
Query: 541 QSLLDSDHNKSDD-IQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWL 717
SL++ + +++ +++++E+L + W L+ + K L +AS QQ+F ++ D E WL
Sbjct: 1563 NSLIERSCDGNEEAMKEQLEQLKEHWDHLLERTNDKGKKLNEASRQQRFNTSIRDFEFWL 1622
Query: 718 AEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADA 897
+E E+ L D +DL S NL KKH LLE ++ + +D + A+ + F+ D
Sbjct: 1623 SEAETLLAMKDQARDLASAGNLLKKHQLLEREMLAREDALKDLNTLAEDLLSSGTFNVDQ 1682
Query: 898 IKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGR 1077
I KK+ V R+ +QE KL +AY L QF++D DDEE WI EK S + GR
Sbjct: 1683 IVKKKDNVNKRFLNVQELAAAHHEKLKEAYALFQFFQDLDDEESWIEEKLIRVSSQDYGR 1742
Query: 1078 DLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSD 1257
DL GVQNL+KKH+ ++ E+ HEP I V + +K+ D +I+ ++ W
Sbjct: 1743 DLQGVQNLLKKHKRLEGELVAHEPAIQNVLDMAEKLKDKAAVGQEEIQLRLAQFVEHWEK 1802
Query: 1258 LKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDA 1437
LK A R L++SLE Q++ +A E E+W+ EK L + G +T++LL KH+A
Sbjct: 1803 LKELAKARGLKLEESLEYLQFMQNAEEEEAWINEKNALAVRGDCGDTLAATQSLLMKHEA 1862
Query: 1438 LMADIEAYRSTIDSLRTQADACKMQEAPVSDSYGKETVMALYDYQEKNP 1584
L D + + + ++ Q + + + +S KE + EK P
Sbjct: 1863 LENDFAVHETRVQNVCAQGEDI-LNKVLHEESQNKEISSKIEALNEKTP 1910
Score = 204 bits (518), Expect = 9e-52
Identities = 110/408 (26%), Positives = 208/408 (50%)
Frame = +1
Query: 256 AADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWIVEKLKTASDEN 435
A ++ ++R ++L R + +E+ R LEDS++ Q+F RDAD++ WI+EK+ +D++
Sbjct: 21 AEEIQERRQEVLTRYQSFKERVAERGQKLEDSYHLQVFKRDADDLGKWIMEKVNILTDKS 80
Query: 436 YKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNKSDDIQQRIEELDKLW 615
Y++PTN+Q K QKHQ+ AE+ + +++ + H+ ++ + IEEL LW
Sbjct: 81 YEDPTNIQGKYQKHQSLEAEVQTKSRLMSELEKTREERFTMGHSAHEETKAHIEELRHLW 140
Query: 616 KDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKKH 795
L+ + K L +A QQ+++ D+ W+ + E+ S + G+D L KK
Sbjct: 141 DLLLELTLEKGDQLLRALKFQQYVQECADILEWIGDKEAIATSVELGEDWERTEVLHKKF 200
Query: 796 NLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNRYSKLQEPLEKRKNKL 975
+ ++ + + R+ Q A++ +NH D I+ KQ EV + +L+ +R+ L
Sbjct: 201 EDFQVELVAKEGRVVEVNQYANECAEENHPDLPLIQSKQNEVNAAWERLRGLALQRQKAL 260
Query: 976 NDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKHQAIQAEVTGHEPRI 1155
++A L +F RD + WI EKEP+ S + G+DL+ + L H+ ++ + ++
Sbjct: 261 SNAANLQRFKRDVTEAIQWIKEKEPVLTSEDYGKDLVASEGLFHSHKGLERNLAVMSDKV 320
Query: 1156 LEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLLDDSLEAQQYLADAS 1335
E+C + +K+ + I++ +D+ + W ++ A R + L + ++ +D
Sbjct: 321 KELCAKAEKLTLSHPSDAPQIQEMKEDLVSSWEHIRALATSRYEKLQATYWYHRFSSDFD 380
Query: 1336 EAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRSTIDS 1479
E WM EK + + E D E LL +H +I++Y S
Sbjct: 381 ELSGWMNEKTAAINADELPTDVAGGEVLLDRHQQHKHEIDSYDDRFQS 428
Score = 198 bits (503), Expect = 5e-50
Identities = 112/505 (22%), Positives = 243/505 (48%), Gaps = 1/505 (0%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
+R+ + LF + WI+ + + ++ + L +E L+ +H++ +
Sbjct: 1280 DRKESLNEAQKFYLFLSKARDLQNWISSIGGMVSSQELAEDLTGIEILLERHQEHRADME 1339
Query: 187 AQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQL 366
A+ Q L+D + +L+++GH+A+ ++ KK + + + +LE+ + RK L+ Q+
Sbjct: 1340 AEAPTFQALEDFSAELIDSGHHASPEIEKKLQAVKLERDDLEKAWEKRKKILDQCLELQM 1399
Query: 367 FDRDADEIKAWIVEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQS 546
F + D++++ +V + + ++ +L++ ++K + I A EG+I D++ +S
Sbjct: 1400 FQGNCDQVESRMVARENSLRSDDKSSLDSLEALMKKRDDLDKAITAQEGKITDLEHFAES 1459
Query: 547 LLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEV 726
L+ +H ++I R++ + WK L + + T L + +QF R++E++E W++E+
Sbjct: 1460 LIADEHYAKEEIATRLQRVLDRWKALKAQLIDERTKLGDYANLKQFYRDLEELEEWISEM 1519
Query: 727 ESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKK 906
D+ KD ++ KH ++ +++ + + + + + K
Sbjct: 1520 -LPTACDESYKDATNIQRKYLKHQTFAHEVDGRSEQVHGVINLGNSLIERSCDGNEEAMK 1578
Query: 907 KQIE-VCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDL 1083
+Q+E + + L E + KLN+A + +F D E W+ E E + + RDL
Sbjct: 1579 EQLEQLKEHWDHLLERTNDKGKKLNEASRQQRFNTSIRDFEFWLSEAETLLAMKDQARDL 1638
Query: 1084 IGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLK 1263
NL+KKHQ ++ E+ E + ++ + ++ + I KK D++ + +++
Sbjct: 1639 ASAGNLLKKHQLLEREMLAREDALKDLNTLAEDLLSSGTFNVDQIVKKKDNVNKRFLNVQ 1698
Query: 1264 NKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALM 1443
A + L ++ Q+ D + ESW+ EK V S ++G+D + LLKKH L
Sbjct: 1699 ELAAAHHEKLKEAYALFQFFQDLDDEESWIEEKLIRVSSQDYGRDLQGVQNLLKKHKRLE 1758
Query: 1444 ADIEAYRSTIDSLRTQADACKMQEA 1518
++ A+ I ++ A+ K + A
Sbjct: 1759 GELVAHEPAIQNVLDMAEKLKDKAA 1783
Score = 195 bits (495), Expect = 4e-49
Identities = 136/503 (27%), Positives = 246/503 (48%), Gaps = 5/503 (0%)
Frame = +1
Query: 4 NERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSL 183
+E+R L +++F+R+ + + I K+ L D G L SV+AL R+HE FE+ L
Sbjct: 1173 DEQRQLLGSAHAVEVFHREADDTKEQIEKKCQALSAADPGSDLFSVQALQRRHEGFERDL 1232
Query: 184 AAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQ 363
+K L + A +L E+ A D+ +++ +L +L+ + K RK SL ++ +
Sbjct: 1233 VPLGDKVTILGETAERLSESHPDATEDLQRQKMELNEAWEDLQGRTKDRKESLNEAQKFY 1292
Query: 364 LFDRDADEIKAWIVE-KLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRG 540
LF A +++ WI +S E ++ T ++ +++HQ A++ A ++
Sbjct: 1293 LFLSKARDLQNWISSIGGMVSSQELAEDLTGIEILLERHQEHRADMEAEAPTFQALEDFS 1352
Query: 541 QSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLA 720
L+DS H+ S +I+++++ + DL A + ++ L Q Q F N + +E +
Sbjct: 1353 AELIDSGHHASPEIEKKLQAVKLERDDLEKAWEKRKKILDQCLELQMFQGNCDQVESRMV 1412
Query: 721 EVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAI 900
E+ L SDD L+S+ L KK + L+ I++ + +I A+ + D H+ + I
Sbjct: 1413 ARENSLRSDD-KSSLDSLEALMKKRDDLDKAITAQEGKITDLEHFAESLIADEHYAKEEI 1471
Query: 901 KKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRD 1080
+ V +R+ L+ L + KL D L QFYRD ++ E+WI E P A + +D
Sbjct: 1472 ATRLQRVLDRWKALKAQLIDERTKLGDYANLKQFYRDLEELEEWISEMLPTACDESY-KD 1530
Query: 1081 LIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMI----DGNHYANRDIEKKIDDMKNL 1248
+Q KHQ EV G ++ V N G +I DGN A ++++++ +K
Sbjct: 1531 ATNIQRKYLKHQTFAHEVDGRSEQVHGVINLGNSLIERSCDGNEEA---MKEQLEQLKEH 1587
Query: 1249 WSDLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKK 1428
W L + + + + L+++ Q++ + E W+ E E L+ + +D S LLKK
Sbjct: 1588 WDHLLERTNDKGKKLNEASRQQRFNTSIRDFEFWLSEAETLLAMKDQARDLASAGNLLKK 1647
Query: 1429 HDALMADIEAYRSTIDSLRTQAD 1497
H L ++ A + L T A+
Sbjct: 1648 HQLLEREMLAREDALKDLNTLAE 1670
Score = 179 bits (455), Expect = 2e-44
Identities = 107/485 (22%), Positives = 230/485 (47%), Gaps = 1/485 (0%)
Frame = +1
Query: 34 MDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQRL 213
+ Q + ++ WI +EA + ++G+ + E L +K EDF+ L A+E + +
Sbjct: 158 LKFQQYVQECADILEWIGDKEAIATSVELGEDWERTEVLHKKFEDFQVELVAKEGRVVEV 217
Query: 214 DDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIK 393
+ AN+ E H + K++++ L A R+ +L ++ N Q F RD E
Sbjct: 218 NQYANECAEENHPDLPLIQSKQNEVNAAWERLRGLALQRQKALSNAANLQRFKRDVTEAI 277
Query: 394 AWIVEKLKTASDENY-KEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNK 570
WI EK + E+Y K+ + H+ +A ++ ++ ++ + L S +
Sbjct: 278 QWIKEKEPVLTSEDYGKDLVASEGLFHSHKGLERNLAVMSDKVKELCAKAEKLTLSHPSD 337
Query: 571 SDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDD 750
+ IQ+ E+L W+ + + + + L +F + +++ W+ E + + +D+
Sbjct: 338 APQIQEMKEDLVSSWEHIRALATSRYEKLQATYWYHRFSSDFDELSGWMNEKTAAINADE 397
Query: 751 CGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNR 930
D+ L +H + +I S+ DR S + V+ NH +D +++K + N
Sbjct: 398 LPTDVAGGEVLLDRHQQHKHEIDSYDDRFQSADETGQDLVNANHEASDEVREKMEILDNN 457
Query: 931 YSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKK 1110
++ L E ++R + H FYRD++ + W+ +E + ++G L + L++K
Sbjct: 458 WTALLELWDERHRQYEQCLDFHLFYRDSEQVDSWMSRQEAFLENEDLGNSLGSAEALLQK 517
Query: 1111 HQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQL 1290
H+ + T E +I+ V K+I +HY + +I+ D + L+ KA RR+L
Sbjct: 518 HEDFEEAFTAQEEKIITVDKTATKLIGDDHYDSENIKAIRDGLLARRDALREKAATRRRL 577
Query: 1291 LDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRST 1470
L +SL Q+ D+ + ++W+ +K+ L ++ KD + ++ ++K ++ ++
Sbjct: 578 LKESLLLQKLYEDSDDLKNWINKKKKLADDEDY-KDIQNLKSRVQKQQVFEKELAVNKTQ 636
Query: 1471 IDSLR 1485
+++++
Sbjct: 637 LENIQ 641
Score = 178 bits (451), Expect = 5e-44
Identities = 122/529 (23%), Positives = 237/529 (44%), Gaps = 9/529 (1%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
ER E + LQ+F RD + WI ++ L + D + ++ +KH+ E +
Sbjct: 44 ERGQKLEDSYHLQVFKRDADDLGKWIMEKVNILTDKSYEDPTN-IQGKYQKHQSLEAEVQ 102
Query: 187 AQEEKTQRLDDIANKLVENGHYAAADVNKKRDDL-----LIRKANLEEKAKLRKGSLEDS 351
+ L+ + GH A + ++L L+ + LE+ +L +
Sbjct: 103 TKSRLMSELEKTREERFTMGHSAHEETKAHIEELRHLWDLLLELTLEKGDQLLRAL---- 158
Query: 352 HNYQLFDRDADEIKAWIVEKLKTASDENYKEPTNLQSKV-QKHQNFLAEIAANEGRIDDV 528
+Q + ++ +I WI +K A+ E + +K ++F E+ A EGR+ +V
Sbjct: 159 -KFQQYVQECADILEWIGDKEAIATSVELGEDWERTEVLHKKFEDFQVELVAKEGRVVEV 217
Query: 529 KSRGQSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDME 708
+ +H IQ + E++ W+ L + ++ L+ A+ Q+F R+V +
Sbjct: 218 NQYANECAEENHPDLPLIQSKQNEVNAAWERLRGLALQRQKALSNAANLQRFKRDVTEAI 277
Query: 709 IWLAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFD 888
W+ E E L S+D GKDL + L H LE +++ D++ +A++ + D
Sbjct: 278 QWIKEKEPVLTSEDYGKDLVASEGLFHSHKGLERNLAVMSDKVKELCAKAEKLTLSHPSD 337
Query: 889 ADAIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTN 1068
A I++ + ++ + + ++ R KL Y H+F D D+ W++EK +
Sbjct: 338 APQIQEMKEDLVSSWEHIRALATSRYEKLQATYWYHRFSSDFDELSGWMNEKTAAINADE 397
Query: 1069 VGRDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNL 1248
+ D+ G + L+ +HQ + E+ ++ R GQ +++ NH A+ ++ +K++ + N
Sbjct: 398 LPTDVAGGEVLLDRHQQHKHEIDSYDDRFQSADETGQDLVNANHEASDEVREKMEILDNN 457
Query: 1249 WSDLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKK 1428
W+ L D+R + + L+ + D+ + +SWM +E + + + G S EALL+K
Sbjct: 458 WTALLELWDERHRQYEQCLDFHLFYRDSEQVDSWMSRQEAFLENEDLGNSLGSAEALLQK 517
Query: 1429 HDALMADIEAYRS---TIDSLRTQADACKMQEAPVSDSYGKETVMALYD 1566
H+ A T+D T+ D Y E + A+ D
Sbjct: 518 HEDFEEAFTAQEEKIITVDKTATKLIG--------DDHYDSENIKAIRD 558
Score = 148 bits (373), Expect = 6e-35
Identities = 113/431 (26%), Positives = 207/431 (48%), Gaps = 1/431 (0%)
Frame = +1
Query: 262 DVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWIVEKLKTASDENYK 441
++ ++++ + + +L ++A+ R+ L +N L +A ++ WI EK +
Sbjct: 1052 NITQRQEQIENQYRSLLDRAEERRRRLLQRYNEFLLAYEAGDMLEWIQEKKAENTGVELD 1111
Query: 442 EPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNKSDDIQQRIEELDKLWKD 621
+ LQ K + Q ++ NE R+ D+ LL + Q R +EL+ W
Sbjct: 1112 DVWELQKKFDEFQK---DLNTNEPRLRDINKVADDLLFEGLLTPEGAQIR-QELNARWGS 1167
Query: 622 LVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKKHNL 801
L + + L A + F R +D + + + L + D G DL SV LQ++H
Sbjct: 1168 LQRLADEQRQLLGSAHAVEVFHREADDTKEQIEKKCQALSAADPGSDLFSVQALQRRHEG 1227
Query: 802 LESDISSHQDRIDSFLQQADQFVHDNHFDA-DAIKKKQIEVCNRYSKLQEPLEKRKNKLN 978
E D+ D++ + L + + + ++H DA + ++++++E+ + LQ + RK LN
Sbjct: 1228 FERDLVPLGDKV-TILGETAERLSESHPDATEDLQRQKMELNEAWEDLQGRTKDRKESLN 1286
Query: 979 DAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKHQAIQAEVTGHEPRIL 1158
+A K + F A D ++WI + S + DL G++ L+++HQ +A++ P
Sbjct: 1287 EAQKFYLFLSKARDLQNWISSIGGMVSSQELAEDLTGIEILLERHQEHRADMEAEAPTFQ 1346
Query: 1159 EVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLLDDSLEAQQYLADASE 1338
+ + ++ID H+A+ +IEKK+ +K DL+ +KR+++LD LE Q + + +
Sbjct: 1347 ALEDFSAELIDSGHHASPEIEKKLQAVKLERDDLEKAWEKRKKILDQCLELQMFQGNCDQ 1406
Query: 1339 AESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRSTIDSLRTQADACKMQEA 1518
ES M +E + S + DS EAL+KK D L I A I L A++ E
Sbjct: 1407 VESRMVARENSLRSDD-KSSLDSLEALMKKRDDLDKAITAQEGKITDLEHFAESLIADE- 1464
Query: 1519 PVSDSYGKETV 1551
Y KE +
Sbjct: 1465 ----HYAKEEI 1471
Score = 121 bits (303), Expect = 8e-27
Identities = 112/519 (21%), Positives = 223/519 (42%), Gaps = 25/519 (4%)
Frame = +1
Query: 49 FYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQRLDDIAN 228
F++D + E+WI ++ + + D G L V+ L++KH+ E L A E Q + D+A
Sbjct: 1717 FFQDLDDEESWIEEKLIRVSSQDYGRDLQGVQNLLKKHKRLEGELVAHEPAIQNVLDMAE 1776
Query: 229 KLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWIVE 408
KL + ++ + + L+E AK R LE+S Y F ++A+E +AWI E
Sbjct: 1777 KLKDKAAVGQEEIQLRLAQFVEHWEKLKELAKARGLKLEESLEYLQFMQNAEEEEAWINE 1836
Query: 409 KLKTASDENYKEP-TNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDS---DHNKSD 576
K A + + QS + KH+ + A +E R+ +V ++G+ +L+ + +++
Sbjct: 1837 KNALAVRGDCGDTLAATQSLLMKHEALENDFAVHETRVQNVCAQGEDILNKVLHEESQNK 1896
Query: 577 DIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDCG 756
+I +IE L++ L A + L Q+F + +E W+A+ E+ L ++ G
Sbjct: 1897 EISSKIEALNEKTPSLAKAIAAWKLQLEDDYAFQEFNWKADVVEAWIADKETSLKTNGNG 1956
Query: 757 KDLNSVTNLQKKHNLLESDISS-HQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNRY 933
DL L K + L++ + S Q+R+ D+ + H + AI+++ + R+
Sbjct: 1957 ADLGDFLTLLAKQDTLDASLQSFQQERLPEITDLKDKLISAQHNQSKAIEERYAALLKRW 2016
Query: 934 SKLQEPLEKRKNKLNDAY--------KLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIG 1089
+L E + KL + +F A +W + E L
Sbjct: 2017 EQLLEASAVHRQKLLEKQLPLQKAEDLFVEFAHKASALNNWCEKMEENLSEPVHCVSLNE 2076
Query: 1090 VQNLIKKHQAIQAEVTGHEPR---ILEVCNEGQKM-IDGNHYANRDIEKKIDDMKNLWSD 1257
++ L K H+ A + + +LE+ + + + + + Y +E ++ W
Sbjct: 2077 IRQLQKDHEDFLASLARAQADFKCLLELDQQIKALGVPSSPYTWLTVEV----LERTWKH 2132
Query: 1258 LKNKADKRRQLLDDSLE--------AQQYLADASEAESWMREKEPLVGSTEFGKDEDSTE 1413
L + ++R Q L Q++ +AS W+ E K+ + E
Sbjct: 2133 LSDIIEEREQELQKEEARQVKNFEMCQEFEQNASTFLQWILETRAYFLDGSLLKETGTLE 2192
Query: 1414 ALLKKHDALMADIEAYRSTIDSLRTQADACKMQEAPVSD 1530
+ L+ + +I+A + + + D +++A + D
Sbjct: 2193 SQLEANKRKQKEIQAMKRQLTKIVDLGD--NLEDALILD 2229
>sp|P08032|SPTA1_MOUSE Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin) Length = 2415 Score = 535 bits (1377), Expect = e-151 Identities = 267/630 (42%), Positives = 407/630 (64%), Gaps = 3/630 (0%) Frame = +1 Query: 1 WNERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKS 180 W++ + Y Q +D LFYRD+EQ ++W+++QEAFLEN D+G+S+ SVEAL++KH+DFE++ Sbjct: 463 WDKCQHQYRQCLDFHLFYRDSEQVDSWMSRQEAFLENEDLGNSVGSVEALLQKHDDFEEA 522 Query: 181 LAAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNY 360 AQEEK LD+ A KL++N HY + ++ RD LL R+ L E+A R+ L DS Sbjct: 523 FTAQEEKIITLDETATKLIDNDHYDSENIAAIRDGLLARRDALRERAATRRKLLVDSQLL 582 Query: 361 QLFDRDADEIKAWIVEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRG 540 Q +D+D++K WI +K K A D++YK+ NL+S+VQK Q+F E+A NE +++++ G Sbjct: 583 QQLYQDSDDLKTWINKKKKLADDDDYKDVQNLKSRVQKQQDFEEELAVNEIMLNNLEKTG 642 Query: 541 QSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLA 720 Q +++ H S+ + R+ E+ LWK+L+ A+ K T L +A+ QF N ED++ WL Sbjct: 643 QEMIEDGHYASEAVAARLSEVANLWKELLEATAQKGTQLYEANQLLQFENNAEDLKRWLE 702 Query: 721 EVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAI 900 EVE Q+ S+D GK L V NL +KH LLESD+++ Q+++D+ A F H D+ I Sbjct: 703 EVEWQVTSEDYGKVLADVQNLLRKHGLLESDVTARQNQMDTLTDMAAHFEEIGHPDSGDI 762 Query: 901 KKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRD 1080 + +Q + +R+ L+EPL RK KL D KL Q RD++DEE WI E EP A ST++G+D Sbjct: 763 RARQESLLSRFEALKEPLAIRKKKLIDLLKLQQICRDSEDEEAWIQETEPSAASTHLGKD 822 Query: 1081 LIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDL 1260 L+ +NL+ +H+ I A++ HEPRI + G KM++ H+A DI +++ + L Sbjct: 823 LVAAKNLLNRHEVILADIASHEPRIQVITERGNKMVEEGHFAAEDIASRVESLNKNMESL 882 Query: 1261 KNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDAL 1440 +A +R L +++ QQYLAD EAE+W++EKEP+V + +G DE++ ALLKKH+A Sbjct: 883 HARAIRRENDLKANVQLQQYLADLHEAEAWIKEKEPIVDNKNYGADEEAAGALLKKHEAF 942 Query: 1441 MADIEAYRSTIDSLRTQADACKMQEAPVSDSYGKET-VMALYDYQEKNpreVSMRKGDVL 1617 + D+ A+ ++I +LR QA+ C+ Q+A D G+E V+ALYD++ ++ REVSM+K DVL Sbjct: 943 LVDLNAFENSIKALRDQAEVCQQQQAAPVDEAGREARVIALYDFEARSRREVSMKKNDVL 1002 Query: 1618 TLLNSNHKDWWKVEINDRQGHVPAAYVKKV--DAMMSDIDPNAPEQITVASQQKNLENQY 1791 TLL+S +KDWWKVE +D QG VPA YV+K+ D + E + + Q+ +E Y Sbjct: 1003 TLLSSINKDWWKVEADDHQGFVPAVYVRKLAPDELPGFPQHQREEPVNIPQLQQQVETLY 1062 Query: 1792 ENLLSLGKDRRDRLKDSVQAYQLVREANDL 1881 +LL ++RR RL + L EA D+ Sbjct: 1063 HSLLDRAEERRRRLLQRYNEFLLAYEAGDM 1092
Score = 315 bits (808), Expect = 2e-85
Identities = 170/501 (33%), Positives = 280/501 (55%), Gaps = 2/501 (0%)
Frame = +1
Query: 1 WNERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKS 180
W R+ + +Q ++LQLF +Q E+W+ +E L ++D D LDS++AL++K +D +K+
Sbjct: 1382 WENRKKMLDQCLELQLFRGKCDQVESWMVARENSLRSDD-RDHLDSLQALMKKRDDLDKA 1440
Query: 181 LAAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNY 360
+ AQE K L+++A +L++N HYA ++ + +L R L+E+ G L D +
Sbjct: 1441 ITAQEGKISDLENVATRLIDNDHYAKEEIAARLQRVLDRWKALKEQLLTELGKLGDYADL 1500
Query: 361 QLFDRDADEIKAWIVEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRG 540
+ F RD ++++ WI E L A DE+YK+PTN+Q K KHQ F E+ ++D V + G
Sbjct: 1501 KQFYRDLEDLEEWINEMLPIACDESYKDPTNIQRKYLKHQAFENEVNGRAEQVDGVINLG 1560
Query: 541 QSLLDSDHNKSDD--IQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIW 714
SL++ D+ +Q++++ L + W L+ + K L +AS QQ+F ++ D E W
Sbjct: 1561 NSLIERRVCDGDEENMQEQLDMLKENWDYLLERTTDKGQKLNEASRQQRFNTSIRDFEFW 1620
Query: 715 LAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDAD 894
L+E E L D +DL S NL KKH LLE+++ + +D + A + + F+ D
Sbjct: 1621 LSEAEGLLAMKDQARDLTSAGNLLKKHQLLEAEMLAREDPLKDLNDLAQELISSGTFNID 1680
Query: 895 AIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVG 1074
I++K V R+ +Q KL + Y L QF++D DDEE WI EK S + G
Sbjct: 1681 QIEEKMNGVNERFENVQSLAAAHHEKLKETYALFQFFQDLDDEEAWIEEKLLRVSSQDYG 1740
Query: 1075 RDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWS 1254
RDL VQNL+KKH+ ++ E+ HEP + V + + + D +I++++ W
Sbjct: 1741 RDLQSVQNLLKKHKRLEGELVAHEPAVQNVLDTAESLRDKAAVGKEEIQERLAQFVQHWE 1800
Query: 1255 DLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHD 1434
LK A R L++SLE Q++ +A E E+W+ EK LV + G +T++LLKKH+
Sbjct: 1801 KLKELAKTRGVNLEESLEYLQFMENAEEEEAWLGEKCALVSRGDSGDTLAATQSLLKKHE 1860
Query: 1435 ALMADIEAYRSTIDSLRTQAD 1497
AL D +++ + + Q +
Sbjct: 1861 ALENDFAVHKNRVQDVCAQGE 1881
Score = 203 bits (517), Expect = 1e-51
Identities = 118/504 (23%), Positives = 247/504 (49%), Gaps = 2/504 (0%)
Frame = +1
Query: 46 LFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQRLDDIA 225
LF E WI + + ++ + L E L+ +H++ + ++ Q L+D
Sbjct: 1291 LFLSKASDLENWIKTIGGVISSPELAEDLTGTEILLERHQEHHDDIKREDPTFQALEDFG 1350
Query: 226 NKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWIV 405
+L+++GH +++ ++ ++ NLE+ + RK L+ QLF D++++W+V
Sbjct: 1351 TELIDSGHRNRREIDNTLQNINSKRDNLEKSWENRKKMLDQCLELQLFRGKCDQVESWMV 1410
Query: 406 EKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNKSDDIQ 585
+ + ++ +LQ+ ++K + I A EG+I D+++ L+D+DH ++I
Sbjct: 1411 ARENSLRSDDRDHLDSLQALMKKRDDLDKAITAQEGKISDLENVATRLIDNDHYAKEEIA 1470
Query: 586 QRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDCGKDL 765
R++ + WK L + L + +QF R++ED+E W+ E+ + D+ KD
Sbjct: 1471 ARLQRVLDRWKALKEQLLTELGKLGDYADLKQFYRDLEDLEEWINEM-LPIACDESYKDP 1529
Query: 766 NSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIK-KKQIEVC-NRYSK 939
++ KH E++++ +++D + + + D D ++Q+++ +
Sbjct: 1530 TNIQRKYLKHQAFENEVNGRAEQVDGVINLGNSLIERRVCDGDEENMQEQLDMLKENWDY 1589
Query: 940 LQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKHQA 1119
L E + KLN+A + +F D E W+ E E + + RDL NL+KKHQ
Sbjct: 1590 LLERTTDKGQKLNEASRQQRFNTSIRDFEFWLSEAEGLLAMKDQARDLTSAGNLLKKHQL 1649
Query: 1120 IQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLLDD 1299
++AE+ E + ++ + Q++I + IE+K++ + + ++++ A + L +
Sbjct: 1650 LEAEMLAREDPLKDLNDLAQELISSGTFNIDQIEEKMNGVNERFENVQSLAAAHHEKLKE 1709
Query: 1300 SLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRSTIDS 1479
+ Q+ D + E+W+ EK V S ++G+D S + LLKKH L ++ A+ + +
Sbjct: 1710 TYALFQFFQDLDDEEAWIEEKLLRVSSQDYGRDLQSVQNLLKKHKRLEGELVAHEPAVQN 1769
Query: 1480 LRTQADACKMQEAPVSDSYGKETV 1551
+ A++ + + A GKE +
Sbjct: 1770 VLDTAESLRDKAA-----VGKEEI 1788
Score = 200 bits (508), Expect = 1e-50
Identities = 129/492 (26%), Positives = 244/492 (49%), Gaps = 3/492 (0%)
Frame = +1
Query: 256 AADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWIVEKLKTASDEN 435
A ++ +R ++L + +++ R LE+S++YQ+F RDAD+++ WI+EKL+ A D+
Sbjct: 20 AEEIQHRRAEVLNQYQRFKDRVAERGQKLEESYHYQVFRRDADDLEKWIMEKLEIAKDKT 79
Query: 436 YKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNKSDDIQQRIEELDKLW 615
Y EPTN+Q K QKH++F++E+ A + +++ ++ DH + + +++L LW
Sbjct: 80 Y-EPTNIQGKYQKHESFVSEVQAKSRVLPELEEIREARFAEDHFAHEATKTHLKQLRLLW 138
Query: 616 KDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKKH 795
L+ ++ K L +A Q+ + ED+ W+ E E+ + + G D L KK
Sbjct: 139 DLLLELTQEKSDVLLRALKFYQYSQECEDILEWVKEKEAIVTLVELGDDWERTEVLHKKF 198
Query: 796 NLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNRYSKLQEPLEKRKNKL 975
+ ++++ + ++D Q A++ + H IK KQ EV + +L KR+ L
Sbjct: 199 EEFQEELTARKGKVDRVNQYANECAQEKHPKLPEIKAKQDEVNAAWDRLWSLALKRRESL 258
Query: 976 NDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKHQAIQAEVTGHEPRI 1155
++A L +F RD ++ W+ EKEP S + G+DL+ + L H+ ++ + + ++
Sbjct: 259 SNAADLQRFKRDVNEAIQWMEEKEPQLTSEDYGKDLVSSEALFHNHKRLERNLAVMDDKV 318
Query: 1156 LEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLLDDSLEAQQYLADAS 1335
E+C + K++ + I++ D+ + W ++ A R L S ++L+D
Sbjct: 319 KELCAKADKLMISHSADALQIQQMKLDLVSNWERIRALATNRYAKLKASYGYHRFLSDYD 378
Query: 1336 EAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRSTIDSLRTQADACKMQE 1515
E WM+EK L+ + E D S EALL +H +I++Y S
Sbjct: 379 ELSGWMKEKTALINADELPTDVASGEALLARHQQHKHEIDSYDDRFQS------------ 426
Query: 1516 APVSDSYGKETVMALYDYQEKNpreVSMRKGDVLTLLNSNHKDWWKVEINDRQ---GHVP 1686
+D+ G+E + ++ E+ ++++ D LL W K + RQ H+
Sbjct: 427 ---ADATGQELLDGNHEASEEIREKMTILANDWAALLEL----WDKCQHQYRQCLDFHLF 479
Query: 1687 AAYVKKVDAMMS 1722
++VD+ MS
Sbjct: 480 YRDSEQVDSWMS 491
Score = 194 bits (492), Expect = 1e-48
Identities = 141/515 (27%), Positives = 245/515 (47%), Gaps = 17/515 (3%)
Frame = +1
Query: 1 WNERRFLYEQNMDL-------QLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRK 159
WN + L ++ L ++F+R+ + + I K+ L D G L SV+AL R+
Sbjct: 1163 WNSLKRLADEQYQLLSSAHAVEMFHREADDVKEQIDKKCRALNAADPGSDLLSVQALQRQ 1222
Query: 160 HEDFEKSLAAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGS 339
HE FE+ + EK L + A +L E+ A D+ K+R +L L+ RK S
Sbjct: 1223 HECFERDIIPLGEKVNTLGETAERLCESHPDATEDLQKQRTELNEAWDTLQGLTSDRKES 1282
Query: 340 LEDSHNYQLFDRDADEIKAWIVEKLKT-----ASDENYKEPTNLQSKVQKHQNFLAEIAA 504
L ++H + LF A +++ WI KT +S E ++ T + +++HQ +I
Sbjct: 1283 LNEAHKFFLFLSKASDLENWI----KTIGGVISSPELAEDLTGTEILLERHQEHHDDIKR 1338
Query: 505 NEGRIDDVKSRGQSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQF 684
+ ++ G L+DS H +I ++ ++ +L + + ++ L Q Q F
Sbjct: 1339 EDPTFQALEDFGTELIDSGHRNRREIDNTLQNINSKRDNLEKSWENRKKMLDQCLELQLF 1398
Query: 685 IRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQ 864
+ +E W+ E+ L SDD L+S+ L KK + L+ I++ + +I A +
Sbjct: 1399 RGKCDQVESWMVARENSLRSDD-RDHLDSLQALMKKRDDLDKAITAQEGKISDLENVATR 1457
Query: 865 FVHDNHFDADAIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEK 1044
+ ++H+ + I + V +R+ L+E L KL D L QFYRD +D E+WI+E
Sbjct: 1458 LIDNDHYAKEEIAARLQRVLDRWKALKEQLLTELGKLGDYADLKQFYRDLEDLEEWINEM 1517
Query: 1045 EPIAGSTNVGRDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMI-----DGNHYAN 1209
PIA + +D +Q KHQA + EV G ++ V N G +I DG+
Sbjct: 1518 LPIACDESY-KDPTNIQRKYLKHQAFENEVNGRAEQVDGVINLGNSLIERRVCDGD---E 1573
Query: 1210 RDIEKKIDDMKNLWSDLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEF 1389
++++++D +K W L + + Q L+++ Q++ + E W+ E E L+ +
Sbjct: 1574 ENMQEQLDMLKENWDYLLERTTDKGQKLNEASRQQRFNTSIRDFEFWLSEAEGLLAMKDQ 1633
Query: 1390 GKDEDSTEALLKKHDALMADIEAYRSTIDSLRTQA 1494
+D S LLKKH L A++ A + L A
Sbjct: 1634 ARDLTSAGNLLKKHQLLEAEMLAREDPLKDLNDLA 1668
Score = 192 bits (487), Expect = 4e-48
Identities = 130/525 (24%), Positives = 243/525 (46%), Gaps = 5/525 (0%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
ER E++ Q+F RD + E WI ++ ++ + +++ +KHE F +
Sbjct: 43 ERGQKLEESYHYQVFRRDADDLEKWIMEKLEIAKDKTYEPT--NIQGKYQKHESFVSEVQ 100
Query: 187 AQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQL 366
A+ L++I H+A L + L E + + L + +
Sbjct: 101 AKSRVLPELEEIREARFAEDHFAHEATKTHLKQLRLLWDLLLELTQEKSDVLLRALKFYQ 160
Query: 367 FDRDADEIKAWIVEK-----LKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVK 531
+ ++ ++I W+ EK L D+ E T + K K + F E+ A +G++D V
Sbjct: 161 YSQECEDILEWVKEKEAIVTLVELGDD--WERTEVLHK--KFEEFQEELTARKGKVDRVN 216
Query: 532 SRGQSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEI 711
H K +I+ + +E++ W L S + + +L+ A+ Q+F R+V +
Sbjct: 217 QYANECAQEKHPKLPEIKAKQDEVNAAWDRLWSLALKRRESLSNAADLQRFKRDVNEAIQ 276
Query: 712 WLAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDA 891
W+ E E QL S+D GKDL S L H LE +++ D++ +AD+ + + DA
Sbjct: 277 WMEEKEPQLTSEDYGKDLVSSEALFHNHKRLERNLAVMDDKVKELCAKADKLMISHSADA 336
Query: 892 DAIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNV 1071
I++ ++++ + + +++ R KL +Y H+F D D+ W+ EK + + +
Sbjct: 337 LQIQQMKLDLVSNWERIRALATNRYAKLKASYGYHRFLSDYDELSGWMKEKTALINADEL 396
Query: 1072 GRDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLW 1251
D+ + L+ +HQ + E+ ++ R GQ+++DGNH A+ +I +K+ + N W
Sbjct: 397 PTDVASGEALLARHQQHKHEIDSYDDRFQSADATGQELLDGNHEASEEIREKMTILANDW 456
Query: 1252 SDLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKH 1431
+ L DK + L+ + D+ + +SWM +E + + + G S EALL+KH
Sbjct: 457 AALLELWDKCQHQYRQCLDFHLFYRDSEQVDSWMSRQEAFLENEDLGNSVGSVEALLQKH 516
Query: 1432 DALMADIEAYRSTIDSLRTQADACKMQEAPVSDSYGKETVMALYD 1566
D A I +L A K+ + +D Y E + A+ D
Sbjct: 517 DDFEEAFTAQEEKIITL--DETATKLID---NDHYDSENIAAIRD 556
Score = 191 bits (486), Expect = 5e-48
Identities = 130/503 (25%), Positives = 243/503 (48%), Gaps = 9/503 (1%)
Frame = +1
Query: 37 DLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQRLD 216
DL+ FYRD E E WI + + D + ++ KH+ FE + + E+ +
Sbjct: 1499 DLKQFYRDLEDLEEWINEMLPIACDESYKDPTN-IQRKYLKHQAFENEVNGRAEQVDGVI 1557
Query: 217 DIANKLVENGHYAAADVNKKRDDLLIRKAN---LEEKAKLRKGSLEDSHNYQLFDRDADE 387
++ N L+E D ++ L + K N L E+ + L ++ Q F+ +
Sbjct: 1558 NLGNSLIER-RVCDGDEENMQEQLDMLKENWDYLLERTTDKGQKLNEASRQQRFNTSIRD 1616
Query: 388 IKAWIVE-KLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDH 564
+ W+ E + A + ++ T+ + ++KHQ AE+ A E + D+ Q L+ S
Sbjct: 1617 FEFWLSEAEGLLAMKDQARDLTSAGNLLKKHQLLEAEMLAREDPLKDLNDLAQELISSGT 1676
Query: 565 NKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGS 744
D I++++ +++ ++++ S + L + QF ++++D E W+ E ++ S
Sbjct: 1677 FNIDQIEEKMNGVNERFENVQSLAAAHHEKLKETYALFQFFQDLDDEEAWIEEKLLRVSS 1736
Query: 745 DDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVC 924
D G+DL SV NL KKH LE ++ +H+ + + L A+ + I+++ +
Sbjct: 1737 QDYGRDLQSVQNLLKKHKRLEGELVAHEPAVQNVLDTAESLRDKAAVGKEEIQERLAQFV 1796
Query: 925 NRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLI 1104
+ KL+E + R L ++ + QF +A++EE W+ EK + + G L Q+L+
Sbjct: 1797 QHWEKLKELAKTRGVNLEESLEYLQFMENAEEEEAWLGEKCALVSRGDSGDTLAATQSLL 1856
Query: 1105 KKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRD-IEKKIDDMKNLWSDLKNKADKR 1281
KKH+A++ + H+ R+ +VC +G+ +++ N+D I KI + + L
Sbjct: 1857 KKHEALENDFAVHKNRVQDVCAQGEDILNKEETQNKDKISTKIQVLNEKTASLAKALAAW 1916
Query: 1282 RQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAY 1461
+ LDD QQ+ A ESW+ EKE + + G D + LL KHD L A ++++
Sbjct: 1917 KSQLDDVHAFQQFNWKADVVESWIGEKEASLKTKSNGADLTAFLTLLAKHDTLDASLQSF 1976
Query: 1462 R----STIDSLRTQADACKMQEA 1518
+ S I L+ Q A + +A
Sbjct: 1977 QQERLSEIAELKDQLVAGEHSQA 1999
Score = 187 bits (475), Expect = 9e-47
Identities = 148/672 (22%), Positives = 305/672 (45%), Gaps = 46/672 (6%)
Frame = +1
Query: 1 WNERRFLYEQNMDLQL----FYRDTEQAE---AWIAKQEAFLENNDVGDSLDSVEALIRK 159
W+ L ++ D+ L FY+ +++ E W+ ++EA + ++GD + E L +K
Sbjct: 138 WDLLLELTQEKSDVLLRALKFYQYSQECEDILEWVKEKEAIVTLVELGDDWERTEVLHKK 197
Query: 160 HEDFEKSLAAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGS 339
E+F++ L A++ K R++ AN+ + H ++ K+D++ L A R+ S
Sbjct: 198 FEEFQEELTARKGKVDRVNQYANECAQEKHPKLPEIKAKQDEVNAAWDRLWSLALKRRES 257
Query: 340 LEDSHNYQLFDRDADEIKAWIVEKLKTASDENY-KEPTNLQSKVQKHQNFLAEIAANEGR 516
L ++ + Q F RD +E W+ EK + E+Y K+ + ++ H+ +A + +
Sbjct: 258 LSNAADLQRFKRDVNEAIQWMEEKEPQLTSEDYGKDLVSSEALFHNHKRLERNLAVMDDK 317
Query: 517 IDDVKSRGQSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNV 696
+ ++ ++ L+ S + IQQ +L W+ + + + + L + G +F+ +
Sbjct: 318 VKELCAKADKLMISHSADALQIQQMKLDLVSNWERIRALATNRYAKLKASYGYHRFLSDY 377
Query: 697 EDMEIWLAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHD 876
+++ W+ E + + +D+ D+ S L +H + +I S+ DR S + +
Sbjct: 378 DELSGWMKEKTALINADELPTDVASGEALLARHQQHKHEIDSYDDRFQSADATGQELLDG 437
Query: 877 NHFDADAIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIA 1056
NH ++ I++K + N ++ L E +K +++ H FYRD++ + W+ +E
Sbjct: 438 NHEASEEIREKMTILANDWAALLELWDKCQHQYRQCLDFHLFYRDSEQVDSWMSRQEAFL 497
Query: 1057 GSTNVGRDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDD 1236
+ ++G + V+ L++KH + T E +I+ + K+ID +HY + +I D
Sbjct: 498 ENEDLGNSVGSVEALLQKHDDFEEAFTAQEEKIITLDETATKLIDNDHYDSENIAAIRDG 557
Query: 1237 MKNLWSDLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEA 1416
+ L+ +A RR+LL DS QQ D+ + ++W+ +K+ L ++ KD + ++
Sbjct: 558 LLARRDALRERAATRRKLLVDSQLLQQLYQDSDDLKTWINKKKKLADDDDY-KDVQNLKS 616
Query: 1417 LLKKHDALMADIEAYRSTIDSLRTQADACKMQEAPVSDSYGKETVMALYDYQE---KNPR 1587
++K ++ +++L QE Y E V A K
Sbjct: 617 RVQKQQDFEEELAVNEIMLNNLEKTG-----QEMIEDGHYASEAVAARLSEVANLWKELL 671
Query: 1588 EVSMRKGDVLTLLN---------SNHKDW-----WKVEINDRQGHVPA---AYVKKVDAM 1716
E + +KG L N + K W W+V D G V A ++K +
Sbjct: 672 EATAQKGTQLYEANQLLQFENNAEDLKRWLEEVEWQVTSED-YGKVLADVQNLLRKHGLL 730
Query: 1717 MSDI------------------DPNAPEQITVASQQKNLENQYENLLSLGKDRRDRLKDS 1842
SD+ + P+ + ++Q++L +++E L R+ +L D
Sbjct: 731 ESDVTARQNQMDTLTDMAAHFEEIGHPDSGDIRARQESLLSRFEALKEPLAIRKKKLIDL 790
Query: 1843 VQAYQLVREAND 1878
++ Q+ R++ D
Sbjct: 791 LKLQQICRDSED 802
Score = 146 bits (368), Expect = 2e-34
Identities = 107/419 (25%), Positives = 194/419 (46%), Gaps = 1/419 (0%)
Frame = +1
Query: 304 NLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWIVEKLKTASDENYKEPTNLQSKVQKHQN 483
+L ++A+ R+ L +N L +A ++ WI EK + + LQ K + Q
Sbjct: 1064 SLLDRAEERRRRLLQRYNEFLLAYEAGDMLEWIQEKKTENTGVELDDVWELQKKFDEFQR 1123
Query: 484 FLAEIAANEGRIDDVKSRGQSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQ 663
++ +NE R+ D+ LL + + R +EL+ W L + + L+
Sbjct: 1124 ---DLKSNEPRLKDINKVADELLFEELLTPEGAHIR-QELNTRWNSLKRLADEQYQLLSS 1179
Query: 664 ASGQQQFIRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDS 843
A + F R +D++ + + L + D G DL SV LQ++H E DI +++++
Sbjct: 1180 AHAVEMFHREADDVKEQIDKKCRALNAADPGSDLLSVQALQRQHECFERDIIPLGEKVNT 1239
Query: 844 FLQQADQFVHDNHFDADAIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDE 1023
+ A++ + + ++K++ E+ + LQ RK LN+A+K F A D
Sbjct: 1240 LGETAERLCESHPDATEDLQKQRTELNEAWDTLQGLTSDRKESLNEAHKFFLFLSKASDL 1299
Query: 1024 EDWIHEKEPIAGSTNVGRDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHY 1203
E+WI + S + DL G + L+++HQ ++ +P + + G ++ID H
Sbjct: 1300 ENWIKTIGGVISSPELAEDLTGTEILLERHQEHHDDIKREDPTFQALEDFGTELIDSGHR 1359
Query: 1204 ANRDIEKKIDDMKNLWSDLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGST 1383
R+I+ + ++ + +L+ + R+++LD LE Q + + ESWM +E + S
Sbjct: 1360 NRREIDNTLQNINSKRDNLEKSWENRKKMLDQCLELQLFRGKCDQVESWMVARENSLRSD 1419
Query: 1384 EFGKDE-DSTEALLKKHDALMADIEAYRSTIDSLRTQADACKMQEAPVSDSYGKETVMA 1557
+ +D DS +AL+KK D L I A I L A +D Y KE + A
Sbjct: 1420 D--RDHLDSLQALMKKRDDLDKAITAQEGKISDLENVA-----TRLIDNDHYAKEEIAA 1471
Score = 142 bits (358), Expect = 3e-33
Identities = 143/680 (21%), Positives = 282/680 (41%), Gaps = 57/680 (8%)
Frame = +1
Query: 10 RRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAA 189
RR L ++ + L Y + E WI QE EN V LD V L +K ++F++ L +
Sbjct: 1073 RRRLLQRYNEFLLAYEAGDMLE-WI--QEKKTENTGV--ELDDVWELQKKFDEFQRDLKS 1127
Query: 190 QEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRK------------ 333
E + + D+NK D+LL + E A +R+
Sbjct: 1128 NEPRLK------------------DINKVADELLFEELLTPEGAHIRQELNTRWNSLKRL 1169
Query: 334 -----GSLEDSHNYQLFDRDADEIKAWIVEKLK--TASDENYKEPTNLQSKVQKHQNFLA 492
L +H ++F R+AD++K I +K + A+D + ++Q+ ++H+ F
Sbjct: 1170 ADEQYQLLSSAHAVEMFHREADDVKEQIDKKCRALNAADPG-SDLLSVQALQRQHECFER 1228
Query: 493 EIAANEGRIDDVKSRGQSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASG 672
+I +++ + + L +S + ++D+Q++ EL++ W L + ++ +L +A
Sbjct: 1229 DIIPLGEKVNTLGETAERLCESHPDATEDLQKQRTELNEAWDTLQGLTSDRKESLNEAHK 1288
Query: 673 QQQFIRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQ 852
F+ D+E W+ + + S + +DL L ++H DI +
Sbjct: 1289 FFLFLSKASDLENWIKTIGGVISSPELAEDLTGTEILLERHQEHHDDIKREDPTFQALED 1348
Query: 853 QADQFVHDNHFDADAIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDW 1032
+ + H + I + ++ L++ E RK L+ +L F D E W
Sbjct: 1349 FGTELIDSGHRNRREIDNTLQNINSKRDNLEKSWENRKKMLDQCLELQLFRGKCDQVESW 1408
Query: 1033 IHEKEPIAGSTNVGRD-LIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYAN 1209
+ +E S + RD L +Q L+KK + +T E +I ++ N ++ID +HYA
Sbjct: 1409 MVARENSLRSDD--RDHLDSLQALMKKRDDLDKAITAQEGKISDLENVATRLIDNDHYAK 1466
Query: 1210 RDIEKKIDDMKNLWSDLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEF 1389
+I ++ + + W LK + L D + +Q+ D + E W+ E P + E
Sbjct: 1467 EEIAARLQRVLDRWKALKEQLLTELGKLGDYADLKQFYRDLEDLEEWINEMLP-IACDES 1525
Query: 1390 GKDEDSTEALLKKHDALMADIEAYRSTIDSLRTQADACKMQEAPVSDSYGKETVMALYDY 1569
KD + + KH A ++ +D + ++ + E V D +E + D
Sbjct: 1526 YKDPTNIQRKYLKHQAFENEVNGRAEQVDGVINLGNS--LIERRVCDG-DEENMQEQLDM 1582
Query: 1570 QEKNpreVSMRKGDVLTLLNSNHK-----------DWWKVE------INDRQGHVPAA-- 1692
++N + R D LN + ++W E + D+ + +A
Sbjct: 1583 LKENWDYLLERTTDKGQKLNEASRQQRFNTSIRDFEFWLSEAEGLLAMKDQARDLTSAGN 1642
Query: 1693 YVKKVDAM----------MSDIDPNAPEQIT--------VASQQKNLENQYENLLSLGKD 1818
+KK + + D++ A E I+ + + + ++EN+ SL
Sbjct: 1643 LLKKHQLLEAEMLAREDPLKDLNDLAQELISSGTFNIDQIEEKMNGVNERFENVQSLAAA 1702
Query: 1819 RRDRLKDSVQAYQLVREAND 1878
++LK++ +Q ++ +D
Sbjct: 1703 HHEKLKETYALFQFFQDLDD 1722
Score = 38.5 bits (88), Expect = 0.068
Identities = 70/329 (21%), Positives = 130/329 (39%), Gaps = 45/329 (13%)
Frame = +1
Query: 10 RRFLYEQNMDLQ----LFYRDTEQAEA---WIAKQEAFLENNDVGDSLDSVEALIRKHED 168
R+ L E+ + LQ LF +A A W E + SL+ + L ++HE
Sbjct: 2024 RQKLLEKQLPLQKAEELFMEFAHKASAFNNWCENAEEDMSEPVHCVSLNEIRQLQKEHEA 2083
Query: 169 FEKSLAAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKAN------LEEKAKLR 330
F SLA +E L ++ +K ++ + ++ D+L R N E + +L+
Sbjct: 2084 FLASLAGAQEDFNYLLEL-DKQIKALNVPSSPYTWLTVDVLGRIWNHLPDIIKEREQELQ 2142
Query: 331 KGSLEDSHNYQL---FDRDADEIKAWIVEKLKTASDEN-YKEPTNLQSKVQKHQNFLAEI 498
K N+++ F+++A WI E D + KE L+S+++ ++ EI
Sbjct: 2143 KEEARQIKNFEMCQEFEQNASAFLQWIQETRAYFLDGSLLKETGTLESQLEANKRKQKEI 2202
Query: 499 AANEGRIDDVKSRGQSLLDS--------------------------DHNKSDDIQQR--I 594
A + + ++ G S+ ++ HN IQ + I
Sbjct: 2203 QAMKRHLTKIEDLGDSMEEALILDIKYSTIGLAQQWDQLHQLGMRMQHNLEQQIQAKDTI 2262
Query: 595 EELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDCGKDLNSV 774
++ K+ + K + NLT ++F + + +L VE K LN+V
Sbjct: 2263 GVSEETLKEFSTTYKHFDENLTGRLTHKEFRSCLRGLNYYLPMVEEGEPEPKFEKFLNAV 2322
Query: 775 TNLQKKHNLLESDISSHQDRIDSFLQQAD 861
+K + LE S D+ ++ +D
Sbjct: 2323 DPGRKGYVSLEDYTSFLIDKESENIKTSD 2351
>sp|P16546|SPTA2_MOUSE Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain) Length = 1458 Score = 428 bits (1101), Expect = e-119 Identities = 218/498 (43%), Positives = 316/498 (63%), Gaps = 2/498 (0%) Frame = +1 Query: 1 WNERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKS 180 W +RR + + ++LQLF+RD EQAE W+A +EAFL D GDSLDSVEALI+KHEDF+K+ Sbjct: 420 WVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKA 479 Query: 181 LAAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNY 360 + QEEK L A++L+ HYA D+ +R+++L R L+ + ++ L +S Sbjct: 480 INVQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVLDRWRRLKAQMIEKRSKLGESQTL 539 Query: 361 QLFDRDADEIKAWIVEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRG 540 Q F RD DEI+AWI EKL+TASDE+YK+PTN+QSK QKHQ F AE+ AN RI V G Sbjct: 540 QQFSRDVDEIEAWISEKLQTASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMG 599 Query: 541 QSLLDSDH--NKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIW 714 SL++ D ++ R+ L W+ LV S K L +A+ QQ F ++D + W Sbjct: 600 NSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFW 659 Query: 715 LAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDAD 894 L+EVE+ L S+D GKDL SV NL KKH LLE+DIS+H+DR+ QAD + + FD Sbjct: 660 LSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTS 719 Query: 895 AIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVG 1074 +K+K+ + R+ K++ R+ KL+++++LHQF+RD DDEE WI EK+ + S + G Sbjct: 720 QVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYG 779 Query: 1075 RDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWS 1254 RDL GVQNL KKH+ ++AE+ HEP I V + G+K+ D N +I++++ W Sbjct: 780 RDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWK 839 Query: 1255 DLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHD 1434 +LK A R Q L++SLE QQ++A+ E E+W+ EK LV S ++G + + LLKKH+ Sbjct: 840 ELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHE 899 Query: 1435 ALMADIEAYRSTIDSLRT 1488 A D ++ ++ + T Sbjct: 900 AFETDFTVHKDRVNDVCT 917
Score = 250 bits (639), Expect = 9e-66
Identities = 158/508 (31%), Positives = 268/508 (52%), Gaps = 4/508 (0%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
ER L ++Q F+RD ++ + WI ++ L ++ G L SV+AL RKHE FE+ LA
Sbjct: 210 ERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLA 269
Query: 187 AQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQL 366
A +K L + A +L+++ +A D+ +K +L +L ++A RK L DSH+ Q
Sbjct: 270 ALGDKVNSLGETAQRLIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDLQR 329
Query: 367 FDRDADEIKAWI--VEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRG 540
F D ++ +WI + L +SDE K+ T ++ +++HQ EI A G + G
Sbjct: 330 FLSDFRDLMSWINGIRGL-VSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFG 388
Query: 541 QSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLA 720
Q LL H S +I+++++ LD+ DL A + L Q F R+ E E W+A
Sbjct: 389 QQLLAHGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMA 448
Query: 721 EVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAI 900
E+ L ++D G L+SV L KKH + I+ +++I + ADQ + +H+ I
Sbjct: 449 AREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGDI 508
Query: 901 KKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRD 1080
++ EV +R+ +L+ + ++++KL ++ L QF RD D+ E WI EK A + +D
Sbjct: 509 ANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESY-KD 567
Query: 1081 LIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRD--IEKKIDDMKNLWS 1254
+Q+ +KHQA +AE+ + RI V + G +I+ A + ++ ++ + + W
Sbjct: 568 PTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQ 627
Query: 1255 DLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHD 1434
L K+ ++ Q L ++ + Q + + + W+ E E L+ S ++GKD S LLKKH
Sbjct: 628 FLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQ 687
Query: 1435 ALMADIEAYRSTIDSLRTQADACKMQEA 1518
L ADI A+ + L +QAD+ A
Sbjct: 688 LLEADISAHEDRLKDLNSQADSLMTSSA 715
Score = 239 bits (611), Expect = 2e-62
Identities = 156/603 (25%), Positives = 305/603 (50%), Gaps = 11/603 (1%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
E+R ++ LQ F RD ++ EAWI+++ + D + +++ +KH+ FE L
Sbjct: 528 EKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTN-IQSKHQKHQAFEAELH 586
Query: 187 AQEEKTQRLDDIANKLVENGHYAAAD--VNKKRDDLLIRKANLEEKAKLRKGSLEDSHNY 360
A ++ + + D+ N L+E G A ++ V + L + L +K+ + L++++
Sbjct: 587 ANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQ 646
Query: 361 QLFDRDADEIKAWIVEKLKTASDENY-KEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSR 537
Q F+ + W+ E + E+Y K+ ++ + ++KHQ A+I+A+E R+ D+ S+
Sbjct: 647 QNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQ 706
Query: 538 GQSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWL 717
SL+ S + ++++ + ++ ++ + S + + L+++ QF R+++D E W+
Sbjct: 707 ADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWI 766
Query: 718 AEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADA 897
E + + S+D G+DL V NL+KKH LE+++++H+ I L + DN +
Sbjct: 767 KEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGQEE 826
Query: 898 IKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGR 1077
I+++ + + +L++ R +L ++ + QF + ++EE WI+EK + S + G
Sbjct: 827 IQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGD 886
Query: 1078 DLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSD 1257
L +Q L+KKH+A + + T H+ R+ +VC GQ +I N++ +I K+ + SD
Sbjct: 887 TLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSD 946
Query: 1258 LKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDA 1437
L+ A +R+ LD++ Q+ A ESW+ EKE + + ++G+D S + LL K +
Sbjct: 947 LEKAAAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQET 1006
Query: 1438 LMADIEAYRSTIDSLRTQADACKMQEAPVSDSYGKETVMALYDYQEK--NpreVSMRKGD 1611
A ++A++ QE + + K+ ++A Q K R S+ K
Sbjct: 1007 FDAGLQAFQ---------------QEGIANITALKDQLLAAKHIQSKAIEARHASLMKRW 1051
Query: 1612 VLTLLNSNHKDWWKVEINDRQGH------VPAAYVKKVDAMMSDIDPNAPEQITVASQQK 1773
L NS + K ++ + Q H + + KK A S + NA E +T +
Sbjct: 1052 TQLLANSATR---KKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFE-NAEEDLTDPVRCN 1107
Query: 1774 NLE 1782
+LE
Sbjct: 1108 SLE 1110
Score = 226 bits (576), Expect = 2e-58
Identities = 125/496 (25%), Positives = 253/496 (51%), Gaps = 3/496 (0%)
Frame = +1
Query: 4 NERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSL 183
++R+ + DLQ F D +WI + ++++ + EAL+ +H++ +
Sbjct: 315 DQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEI 374
Query: 184 AAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQ 363
A+ Q + +L+ +GHYA+ ++ +K D L + +LE+ R+ L+ Q
Sbjct: 375 DARAGTFQAFEQFGQQLLAHGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQ 434
Query: 364 LFDRDADEIKAWIVEKLKTASDENYKEP-TNLQSKVQKHQNFLAEIAANEGRIDDVKSRG 540
LF RD ++ + W+ + + E+ + ++++ ++KH++F I E +I +++
Sbjct: 435 LFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFA 494
Query: 541 QSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLA 720
L+ DH DI R E+ W+ L + K + L ++ QQF R+V+++E W++
Sbjct: 495 DQLIAVDHYAKGDIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWIS 554
Query: 721 EVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHF--DAD 894
E + Q SD+ KD ++ + +KH E+++ ++ DRI + + + D
Sbjct: 555 E-KLQTASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSED 613
Query: 895 AIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVG 1074
A+K + + +++ L + ++ KL +A K F D + W+ E E + S + G
Sbjct: 614 AVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYG 673
Query: 1075 RDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWS 1254
+DL V NL+KKHQ ++A+++ HE R+ ++ ++ ++ + + +++K D + +
Sbjct: 674 KDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQ 733
Query: 1255 DLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHD 1434
+K+ A RR L +S Q+ D + ESW++EK+ LV S ++G+D + L KKH
Sbjct: 734 KIKSMATSRRAKLSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHK 793
Query: 1435 ALMADIEAYRSTIDSL 1482
L A++ A+ I +
Sbjct: 794 RLEAELAAHEPAIQGV 809
Score = 211 bits (538), Expect = 4e-54
Identities = 162/696 (23%), Positives = 312/696 (44%), Gaps = 72/696 (10%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
+R+ + E++ + +R+ + + WI ++EA L N +VG L+ VE L +K +DF+K L
Sbjct: 68 KRKGMLEKSCKKFMLFREANELQQWITEKEAALTNEEVGADLEQVEVLQKKFDDFQKDLK 127
Query: 187 AQEEKTQRLDDIANKLVENGHYA------------------------------------- 255
A E + + ++ +A L G A
Sbjct: 128 ANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGAMPRDEADSKTASPWKSARLMVHT 187
Query: 256 AADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWIVEKLKTASDEN 435
A N ++ L R +L++ A+ R L +H Q F RDADE K WI EK + + +N
Sbjct: 188 VATFNSIKE-LNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDN 246
Query: 436 Y-KEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNKSDDIQQRIEELDKL 612
Y + ++Q+ +KH+ F ++AA +++ + Q L+ S ++D++++ EL++
Sbjct: 247 YGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAQRLIQSHPESAEDLKEKCTELNQA 306
Query: 613 WKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKK 792
W L + ++ L + Q+F+ + D+ W+ + + SD+ KD+ L ++
Sbjct: 307 WTSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLER 366
Query: 793 HNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNRYSKLQEPLEKRKNK 972
H ++I + +F Q Q + H+ + IK+K + + L++ +R+
Sbjct: 367 HQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKEKLDILDQERTDLEKAWVQRRMM 426
Query: 973 LNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKHQAIQAEVTGHEPR 1152
L+ +L F+RD + E+W+ +E + + G L V+ LIKKH+ + E +
Sbjct: 427 LDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEK 486
Query: 1153 ILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLLDDSLEAQQYLADA 1332
I + ++I +HYA DI + +++ + W LK + ++R L +S QQ+ D
Sbjct: 487 IAALQAFADQLIAVDHYAKGDIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDV 546
Query: 1333 SEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEA----YRSTID-------- 1476
E E+W+ EK S E KD + ++ +KH A A++ A R ID
Sbjct: 547 DEIEAWISEKLQ-TASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIER 605
Query: 1477 -SLRTQADACKMQEAPVSDSY------GKETVMALYDYQEKNpreVSMRKGD-----VLT 1620
+ DA K + A ++D + E L + ++ ++ D V
Sbjct: 606 GACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEA 665
Query: 1621 LLNSNH--KDWWKVEINDRQGHVPAAYVKKVDAMMSDIDPNAPEQIT--------VASQQ 1770
LL S KD V ++ + A + + + D++ A +T V ++
Sbjct: 666 LLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKR 725
Query: 1771 KNLENQYENLLSLGKDRRDRLKDSVQAYQLVREAND 1878
+ +++ + S+ RR +L +S + +Q R+ +D
Sbjct: 726 DTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDD 761
Score = 177 bits (449), Expect = 9e-44
Identities = 114/436 (26%), Positives = 212/436 (48%), Gaps = 38/436 (8%)
Frame = +1
Query: 304 NLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWIVEKLKTASDENY-KEPTNLQSKVQKHQ 480
+L E + RKG LE S + R+A+E++ WI EK ++E + ++ +K
Sbjct: 61 SLLELGEKRKGMLEKSCKKFMLFREANELQQWITEKEAALTNEEVGADLEQVEVLQKKFD 120
Query: 481 NFLAEIAANEGRIDDVKSRGQSLLDSDHNKSDDIQ------------------------- 585
+F ++ ANE R+ D+ + L+S+ ++++Q
Sbjct: 121 DFQKDLKANESRLKDINKVAED-LESEGLMAEEVQAVQQQEVYGAMPRDEADSKTASPWK 179
Query: 586 ------------QRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVE 729
I+EL++ W+ L ++ + L A Q+F R+ ++ + W+ E
Sbjct: 180 SARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKN 239
Query: 730 SQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKK 909
L +D+ G DL SV LQ+KH E D+++ D+++S + A + + + A+ +K+K
Sbjct: 240 QALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAQRLIQSHPESAEDLKEK 299
Query: 910 QIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIG 1089
E+ ++ L + ++RK KL D++ L +F D D WI+ + S + +D+ G
Sbjct: 300 CTELNQAWTSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTG 359
Query: 1090 VQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNK 1269
+ L+++HQ + E+ GQ+++ HYA+ +I++K+D + +DL+
Sbjct: 360 AEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKEKLDILDQERTDLEKA 419
Query: 1270 ADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMAD 1449
+RR +LD LE Q + D +AE+WM +E + + + G DS EAL+KKH+
Sbjct: 420 WVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKA 479
Query: 1450 IEAYRSTIDSLRTQAD 1497
I I +L+ AD
Sbjct: 480 INVQEEKIAALQAFAD 495
Score = 138 bits (347), Expect = 6e-32
Identities = 87/375 (23%), Positives = 175/375 (46%), Gaps = 36/375 (9%)
Frame = +1
Query: 463 KVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKI 642
+V Q F+ AA ++D +S + L + I R ++D ++ L+ +
Sbjct: 14 EVNDRQGFVP--AAYVKKLDPAQSASRENLLEEQGS---IALRQGQIDNQYQSLLELGEK 68
Query: 643 KETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISS 822
++ L ++ + R +++ W+ E E+ L +++ G DL V LQKK + + D+ +
Sbjct: 69 RKGMLEKSCKKFMLFREANELQQWITEKEAALTNEEVGADLEQVEVLQKKFDDFQKDLKA 128
Query: 823 HQDRIDSFLQQADQFVHDNHF--DADAIKKKQI--------------------------- 915
++ R+ + A+ + + A++++++
Sbjct: 129 NESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGAMPRDEADSKTASPWKSARLMVHTV 188
Query: 916 -------EVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVG 1074
E+ R+ LQ+ E+R L A+++ +F+RDAD+ ++WI EK + N G
Sbjct: 189 ATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYG 248
Query: 1075 RDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWS 1254
DL VQ L +KH+ + ++ ++ + Q++I + + D+++K ++ W+
Sbjct: 249 HDLASVQALQRKHEGFERDLAALGDKVNSLGETAQRLIQSHPESAEDLKEKCTELNQAWT 308
Query: 1255 DLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHD 1434
L +AD+R+ L DS + Q++L+D + SW+ LV S E KD EALL++H
Sbjct: 309 SLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQ 368
Query: 1435 ALMADIEAYRSTIDS 1479
+I+A T +
Sbjct: 369 EHRTEIDARAGTFQA 383
Score = 94.4 bits (233), Expect = 1e-18
Identities = 47/88 (53%), Positives = 63/88 (71%), Gaps = 1/88 (1%)
Frame = +1
Query: 1621 LLNSNHKDWWKVEINDRQGHVPAAYVKKVDAMMSDIDPN-APEQITVASQQKNLENQYEN 1797
LLNS +KDWWKVE+NDRQG VPAAYVKK+D S N EQ ++A +Q ++NQY++
Sbjct: 2 LLNSTNKDWWKVEVNDRQGFVPAAYVKKLDPAQSASRENLLEEQGSIALRQGQIDNQYQS 61
Query: 1798 LLSLGKDRRDRLKDSVQAYQLVREANDL 1881
LL LG+ R+ L+ S + + L REAN+L
Sbjct: 62 LLELGEKRKGMLEKSCKKFMLFREANEL 89
Score = 47.8 bits (112), Expect = 1e-04
Identities = 24/85 (28%), Positives = 42/85 (49%)
Frame = +1
Query: 1243 NLWSDLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALL 1422
N + L +KR+ +L+ S + +A+E + W+ EKE + + E G D + E L
Sbjct: 57 NQYQSLLELGEKRKGMLEKSCKKFMLFREANELQQWITEKEAALTNEEVGADLEQVEVLQ 116
Query: 1423 KKHDALMADIEAYRSTIDSLRTQAD 1497
KK D D++A S + + A+
Sbjct: 117 KKFDDFQKDLKANESRLKDINKVAE 141
>sp|Q01082|SPTB2_HUMAN Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain) Length = 2364 Score = 317 bits (811), Expect = 1e-85 Identities = 179/511 (35%), Positives = 286/511 (55%), Gaps = 1/511 (0%) Frame = +1 Query: 1 WNERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKS 180 W R+ L Q+ Q F RDT+QAEA++ QE L + ++ +L+ EA I+K EDF + Sbjct: 1158 WENRQNLLSQSHAYQQFLRDTKQAEAFLNNQEYVLAHTEMPTTLEGAEAAIKKQEDFMTT 1217 Query: 181 LAAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNY 360 + A EEK + + +LV +G+ + + +K D + R E A L+D+ + Sbjct: 1218 MDANEEKINAVVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNRETASELLMRLKDNRDL 1277 Query: 361 QLFDRDADEIKAWIVEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRG 540 Q F +D E+ WI EK+ TA D +Y E NL SK KHQ F+AE+A+N+ +D ++ G Sbjct: 1278 QKFLQDCQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEG 1337 Query: 541 QSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLA 720 L+ +++++ L K+W+ L S ++ K L A+ + F ++ D++ WL Sbjct: 1338 MQLISEKPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLH 1397 Query: 721 EVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAI 900 +ESQ+ SDD GK L SV L KK +LE+ + + I+ QA Q + D + Sbjct: 1398 GLESQIQSDDYGKHLTSVNILLKKQQMLENQMEVRKKEIEELQSQA-QALSQEGKSTDEV 1456 Query: 901 KKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRD 1080 K++ V ++ +L EPL +RK+ L + ++HQF RD +DE W+ E+ P+A ST+ G + Sbjct: 1457 DSKRLTVQTKFMELLEPLNERKHNLLASKEIHQFNRDVEDEILWVGERMPLATSTDHGHN 1516 Query: 1081 LIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMI-DGNHYANRDIEKKIDDMKNLWSD 1257 L VQ LIKK+Q +Q E+ GH+PRI ++ Q ++ D + + I +++ D+K LW Sbjct: 1517 LQTVQLLIKKNQTLQKEIQGHQPRIDDIFERSQNIVTDSSSLSAEAIRQRLADLKQLWGL 1576 Query: 1258 LKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDA 1437 L + +KR + L+++ AQQY DA+EAE+WM E+E + S E KDE S ++LKKH Sbjct: 1577 LIEETEKRHRRLEEAHRAQQYYFDAAEAEAWMSEQELYMMSEEKAKDEQSAVSMLKKHQI 1636 Query: 1438 LMADIEAYRSTIDSLRTQADACKMQEAPVSD 1530 L +E Y T+ L + A P S+ Sbjct: 1637 LEQAVEDYAETVHQLSKTSRALVADSHPESE 1667
Score = 211 bits (538), Expect = 4e-54
Identities = 138/501 (27%), Positives = 259/501 (51%), Gaps = 5/501 (0%)
Frame = +1
Query: 43 QLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQRLDDI 222
+LF + + W+ E+ ++++D G L SV L++K + E + ++++ + L
Sbjct: 1383 ELFTQSCADLDKWLHGLESQIQSDDYGKHLTSVNILLKKQQMLENQMEVRKKEIEELQSQ 1442
Query: 223 ANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWI 402
A L + G + +V+ KR + + L E RK +L S F+RD ++ W+
Sbjct: 1443 AQALSQEGK-STDEVDSKRLTVQTKFMELLEPLNERKHNLLASKEIHQFNRDVEDEILWV 1501
Query: 403 VEK--LKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLL-DSDHNKS 573
E+ L T++D + T +Q ++K+Q EI ++ RIDD+ R Q+++ DS +
Sbjct: 1502 GERMPLATSTDHGHNLQT-VQLLIKKNQTLQKEIQGHQPRIDDIFERSQNIVTDSSSLSA 1560
Query: 574 DDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDC 753
+ I+QR+ +L +LW L+ ++ + L +A QQ+ + + E W++E E + S++
Sbjct: 1561 EAIRQRLADLKQLWGLLIEETEKRHRRLEEAHRAQQYYFDAAEAEAWMSEQELYMMSEEK 1620
Query: 754 GKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNRY 933
KD S ++ KKH +LE + + + + + + V D+H +++ I +Q +V Y
Sbjct: 1621 AKDEQSAVSMLKKHQILEQAVEDYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLY 1680
Query: 934 SKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKH 1113
+ L++ E+R+ KL++ ++L Q R+ DD E WI E+E +AGS +G+D V L ++
Sbjct: 1681 AGLKDLAEERRGKLDERHRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERF 1740
Query: 1114 QAIQAEVTGH--EPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQ 1287
+ A TG+ + R+ V + ++I+ H I + D + W+DL D R Q
Sbjct: 1741 REF-ARDTGNIGQERVDTVNHLADELINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQ 1799
Query: 1288 LLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRS 1467
+L S E ++ DA E +++K + E G+D+++ E L + H DI+A +
Sbjct: 1800 ILAASYELHKFYHDAKEIFGRIQDKHKKL-PEELGRDQNTVETLQRMHTTFEHDIQALGT 1858
Query: 1468 TIDSLRTQADACKMQEAPVSD 1530
+ L Q DA ++Q A D
Sbjct: 1859 QVRQL--QEDAARLQAAYAGD 1877
Score = 204 bits (518), Expect = 9e-52
Identities = 118/520 (22%), Positives = 255/520 (49%), Gaps = 2/520 (0%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
ERR E++ L F+ + + E WI ++E L ++D G L SV L+ KH FE ++
Sbjct: 629 ERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMS 688
Query: 187 AQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQL 366
+ ++ ++ H+ + + ++ + + ANLE+ + +RK LE++
Sbjct: 689 GRSGHFEQAIKEGEDMIAEEHFGSEKIRERIIYIREQWANLEQLSAIRKKRLEEASLLHQ 748
Query: 367 FDRDADEIKAWIVEKLKTASDENY-KEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQ 543
F DAD+I AW+++ LK S + + + QS V+KH++ EIA +D + +
Sbjct: 749 FQADADDIDAWMLDILKIVSSSDVGHDEYSTQSLVKKHKDVAEEIANYRPTLDTLHEQA- 807
Query: 544 SLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAE 723
S L +H +S D++ R+ +++ +K++ +++++ L + + E+W+ E
Sbjct: 808 SALPQEHAESPDVRGRLSGIEERYKEVAELTRLRKQALQDTLALYKMFSEADACELWIDE 867
Query: 724 VESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIK 903
E L + + L + +Q + LE ++++ R+ Q A Q +H H IK
Sbjct: 868 KEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHSGHPSEKEIK 927
Query: 904 KKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGST-NVGRD 1080
+Q ++ R+S+ +E ++++K+ L A + ++ + ++ + WI EK + ST ++G D
Sbjct: 928 AQQDKLNTRWSQFRELVDRKKDALLSALSIQNYHLECNETKSWIREKTKVIESTQDLGND 987
Query: 1081 LIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDL 1260
L GV L +K ++ ++ E ++ ++ E +K+ + + I ++ ++ ++W ++
Sbjct: 988 LAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRLAEISDVWEEM 1047
Query: 1261 KNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDAL 1440
K R L ++ + QQ+L D + +SW+ + + S + E LL +H+ +
Sbjct: 1048 KTTLKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENI 1107
Query: 1441 MADIEAYRSTIDSLRTQADACKMQEAPVSDSYGKETVMAL 1560
+I+ Y +R + + + ++ + AL
Sbjct: 1108 KNEIDNYEEDYQKMRDMGEMVTQGQTDAQYMFLRQRLQAL 1147
Score = 194 bits (493), Expect = 7e-49
Identities = 122/436 (27%), Positives = 223/436 (51%), Gaps = 8/436 (1%)
Frame = +1
Query: 259 ADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQL---FDRDADEIKAWIVEKLKTASD 429
+D+NK + L KA E + LR + QL FDR A + W+ E + S
Sbjct: 390 SDINKAWERL--EKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQ 447
Query: 430 ENYK-EPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNKSDDIQQRIEELD 606
+N+ + +++ +KH+ +IAA E R+ V + + L +++ I R + +
Sbjct: 448 DNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVARELEAENYHDIKRITARKDNVI 507
Query: 607 KLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQ 786
+LW+ L+ + + L G Q+ + + + W+ E++ + S D GK L V +L
Sbjct: 508 RLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDEMKVLVLSQDYGKHLLGVEDLL 567
Query: 787 KKHNLLESDISSHQDRIDSFLQQADQFVHDNH----FDADAIKKKQIEVCNRYSKLQEPL 954
+KH L+E+DI +R+ A +F D D I+ + + Y +L +
Sbjct: 568 QKHTLVEADIGIQAERVRGVNASAQKFATDGEGYKPCDPQVIRDRVAHMEFCYQELCQLA 627
Query: 955 EKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKHQAIQAEV 1134
+R+ +L ++ +L +F+ + +EE WI EKE I S + G+DL V L+ KH+A + E+
Sbjct: 628 AERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEM 687
Query: 1135 TGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLLDDSLEAQ 1314
+G + EG+ MI H+ + I ++I ++ W++L+ + R++ L+++
Sbjct: 688 SGRSGHFEQAIKEGEDMIAEEHFGSEKIRERIIYIREQWANLEQLSAIRKKRLEEASLLH 747
Query: 1315 QYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRSTIDSLRTQA 1494
Q+ ADA + ++WM + +V S++ G DE ST++L+KKH + +I YR T+D+L QA
Sbjct: 748 QFQADADDIDAWMLDILKIVSSSDVGHDEYSTQSLVKKHKDVAEEIANYRPTLDTLHEQA 807
Query: 1495 DACKMQEAPVSDSYGK 1542
A + A D G+
Sbjct: 808 SALPQEHAESPDVRGR 823
Score = 190 bits (482), Expect = 1e-47
Identities = 116/480 (24%), Positives = 231/480 (48%), Gaps = 5/480 (1%)
Frame = +1
Query: 49 FYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQRLDDIAN 228
F R E W+++ + + ++ G L +VEA +KHE E +AA EE+ Q + +A
Sbjct: 427 FDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVAR 486
Query: 229 KLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWIVE 408
+L ++ + ++D+++ L E + R+ LE + Q ++ I W+ E
Sbjct: 487 ELEAENYHDIKRITARKDNVIRLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDE 546
Query: 409 -KLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSL-LDSDHNKSDD- 579
K+ S + K ++ +QKH A+I R+ V + Q D + K D
Sbjct: 547 MKVLVLSQDYGKHLLGVEDLLQKHTLVEADIGIQAERVRGVNASAQKFATDGEGYKPCDP 606
Query: 580 --IQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDC 753
I+ R+ ++ +++L + + L ++ +F + + E W+ E E L SDD
Sbjct: 607 QVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDY 666
Query: 754 GKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNRY 933
GKDL SV L KH E ++S + +++ + + + HF ++ I+++ I + ++
Sbjct: 667 GKDLTSVMRLLSKHRAFEDEMSGRSGHFEQAIKEGEDMIAEEHFGSEKIRERIIYIREQW 726
Query: 934 SKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKH 1113
+ L++ RK +L +A LHQF DADD + W+ + I S++VG D Q+L+KKH
Sbjct: 727 ANLEQLSAIRKKRLEEASLLHQFQADADDIDAWMLDILKIVSSSDVGHDEYSTQSLVKKH 786
Query: 1114 QAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLL 1293
+ + E+ + P L+ +E + H + D+ ++ ++ + ++ R+Q L
Sbjct: 787 KDVAEEIANYRP-TLDTLHEQASALPQEHAESPDVRGRLSGIEERYKEVAELTRLRKQAL 845
Query: 1294 DDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRSTI 1473
D+L + ++A E W+ EKE + + + + + E + + ++L ++ S +
Sbjct: 846 QDTLALYKMFSEADACELWIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRV 905
Score = 179 bits (453), Expect = 3e-44
Identities = 114/470 (24%), Positives = 229/470 (48%), Gaps = 5/470 (1%)
Frame = +1
Query: 43 QLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQRLDDI 222
Q +Y D +AEAW+++QE ++ + + S ++++KH+ E+++ E +L
Sbjct: 1595 QQYYFDAAEAEAWMSEQELYMMSEEKAKDEQSAVSMLKKHQILEQAVEDYAETVHQLSKT 1654
Query: 223 ANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWI 402
+ LV + H + ++ ++ + A L++ A+ R+G L++ H +R+ D+++ WI
Sbjct: 1655 SRALVADSHPESERISMRQSKVDKLYAGLKDLAEERRGKLDERHRLFQLNREVDDLEQWI 1714
Query: 403 VEKLKTASD----ENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNK 570
E+ A ++Y+ T LQ + ++ I + R+D V L++S H+
Sbjct: 1715 AEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIG--QERVDTVNHLADELINSGHSD 1772
Query: 571 SDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDD 750
+ I + + L++ W DL+ + L + +F + +++ + + +L ++
Sbjct: 1773 AATIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKEIFGRIQDKHKKL-PEE 1831
Query: 751 CGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFD-ADAIKKKQIEVCN 927
G+D N+V LQ+ H E DI + ++ + A + D AD I+K++ EV
Sbjct: 1832 LGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADDIQKRENEVLE 1891
Query: 928 RYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIK 1107
+ L + E R+ +L D +F+ D W+ + + RD+ V+ L+
Sbjct: 1892 AWKSLLDACESRRVRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPRDVSSVELLMN 1951
Query: 1108 KHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQ 1287
HQ I+AE+ G+ ++ HYA+ +I++K+ + ++ +K + R +
Sbjct: 1952 NHQGIKAEIDARNDSFTTCIELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWE 2011
Query: 1288 LLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDA 1437
L LE Q+ DAS AE+W+ +EP + S E G+ D E L+K+H+A
Sbjct: 2012 WLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIGQSVDEVEKLIKRHEA 2061
Score = 165 bits (418), Expect = 4e-40
Identities = 145/658 (22%), Positives = 307/658 (46%), Gaps = 44/658 (6%)
Frame = +1
Query: 40 LQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQRLDD 219
LQ F RD + ++W+++ + + + D+ ++L E L+ +HE+ + + EE Q++ D
Sbjct: 1064 LQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENIKNEIDNYEEDYQKMRD 1123
Query: 220 IANKLVENGHYAAADVNKKRDDLLIRKAN-LEEKAKLRKGSLEDSHNYQLFDRDADEIKA 396
+ + + A ++R L N L + + R+ L SH YQ F RD + +A
Sbjct: 1124 MGEMVTQGQTDAQYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQQFLRDTKQAEA 1183
Query: 397 WIVEKLKTASDENYKEPTNLQ---SKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHN 567
++ + + + + PT L+ + ++K ++F+ + ANE +I+ V G+ L+ +
Sbjct: 1184 FLNNQEYVLA--HTEMPTTLEGAEAAIKKQEDFMTTMDANEEKINAVVETGRRLVSDGNI 1241
Query: 568 KSDDIQQRIEELD-KLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGS 744
SD IQ++++ +D + K+ +AS++ L Q+F+++ +++ +W+ E L +
Sbjct: 1242 NSDRIQEKVDSIDDRHRKNRETASELL-MRLKDNRDLQKFLQDCQELSLWINE--KMLTA 1298
Query: 745 DDCGKDLNSVTNLQKK---HNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQI 915
D D NL K H ++++S+++ +D ++ Q + + +K+K
Sbjct: 1299 QDMSYD--EARNLHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISEKPETEAVVKEKLT 1356
Query: 916 EVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQ 1095
+ + L+ + + +L DA K F + D + W+H E S + G+ L V
Sbjct: 1357 GLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYGKHLTSVN 1416
Query: 1096 NLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKAD 1275
L+KK Q ++ ++ + I E+ ++ Q + + +++ K ++ + +L +
Sbjct: 1417 ILLKKQQMLENQMEVRKKEIEELQSQAQALSQEGKSTD-EVDSKRLTVQTKFMELLEPLN 1475
Query: 1276 KRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIE 1455
+R+ L S E Q+ D + W+ E+ PL ST+ G + + + L+KK+ L +I+
Sbjct: 1476 ERKHNLLASKEIHQFNRDVEDEILWVGERMPLATSTDHGHNLQTVQLLIKKNQTLQKEIQ 1535
Query: 1456 AYRSTIDSL--RTQ----------ADACKMQEAPVSDSYG-------------KETVMAL 1560
++ ID + R+Q A+A + + A + +G +E A
Sbjct: 1536 GHQPRIDDIFERSQNIVTDSSSLSAEAIRQRLADLKQLWGLLIEETEKRHRRLEEAHRAQ 1595
Query: 1561 YDYQEKNpreVSMRKGDVLTLLNSNHKDWW-------KVEINDRQGHVPAAYVKKVD--- 1710
Y + E M + ++ + KD K +I ++ A V ++
Sbjct: 1596 QYYFDAAEAEAWMSEQELYMMSEEKAKDEQSAVSMLKKHQILEQAVEDYAETVHQLSKTS 1655
Query: 1711 -AMMSDIDPNAPEQITVASQQKNLENQYENLLSLGKDRRDRLKDSVQAYQLVREANDL 1881
A+++D + PE ++ +Q ++ Y L L ++RR +L + + +QL RE +DL
Sbjct: 1656 RALVAD---SHPESERISMRQSKVDKLYAGLKDLAEERRGKLDERHRLFQLNREVDDL 1710
Score = 163 bits (413), Expect = 1e-39
Identities = 140/650 (21%), Positives = 288/650 (44%), Gaps = 24/650 (3%)
Frame = +1
Query: 1 WNERRFLYEQNMD-------LQLFYRDTEQAEAWIAKQEAFLENN-DVGDSLDSVEALIR 156
W++ R L ++ D +Q ++ + + ++WI ++ +E+ D+G+ L V AL R
Sbjct: 937 WSQFRELVDRKKDALLSALSIQNYHLECNETKSWIREKTKVIESTQDLGNDLAGVMALQR 996
Query: 157 KHEDFEKSLAAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKG 336
K E+ L A E K L A KL A + + ++ ++ K R+
Sbjct: 997 KLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRLAEISDVWEEMKTTLKNREA 1056
Query: 337 SLEDSHNYQLFDRDADEIKAWIVE-KLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEG 513
SL ++ Q F RD D+ ++W+ + AS++ T + + +H+N EI E
Sbjct: 1057 SLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENIKNEIDNYEE 1116
Query: 514 RIDDVKSRGQSLLDSDHNKSDD-IQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIR 690
++ G+ + + ++QR++ LD W +L + ++ L+Q+ QQF+R
Sbjct: 1117 DYQKMRDMGEMVTQGQTDAQYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQQFLR 1176
Query: 691 NVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFV 870
+ + E +L E L + L KK + + +++++I++ ++ + V
Sbjct: 1177 DTKQAEAFLNNQEYVLAHTEMPTTLEGAEAAIKKQEDFMTTMDANEEKINAVVETGRRLV 1236
Query: 871 HDNHFDADAIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEP 1050
D + ++D I++K + +R+ K +E + +L D L +F +D + WI+EK
Sbjct: 1237 SDGNINSDRIQEKVDSIDDRHRKNRETASELLMRLKDNRDLQKFLQDCQELSLWINEKML 1296
Query: 1051 IAGSTNVGRDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKI 1230
A + + + + KHQA AE+ ++ + ++ EG ++I +++K+
Sbjct: 1297 TAQDMSYD-EARNLHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISEKPETEAVVKEKL 1355
Query: 1231 DDMKNLWSDLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDST 1410
+ +W L++ + Q L D+ +A+ + ++ + W+ E + S ++GK S
Sbjct: 1356 TGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYGKHLTSV 1415
Query: 1411 EALLKKHDALMADIEAYRSTIDSLRTQADACKMQEAPVSDSYGKETVMALYDYQE----K 1578
LLKK L +E + I+ L++QA A QE +D + + + E
Sbjct: 1416 NILLKKQQMLENQMEVRKKEIEELQSQAQALS-QEGKSTDEVDSKRLTVQTKFMELLEPL 1474
Query: 1579 NpreVSMRKGDVLTLLNSNHKD---W----WKVEINDRQGH---VPAAYVKKVDAMMSDI 1728
N R+ ++ + N + +D W + + GH +KK + +I
Sbjct: 1475 NERKHNLLASKEIHQFNRDVEDEILWVGERMPLATSTDHGHNLQTVQLLIKKNQTLQKEI 1534
Query: 1729 DPNAPEQITVASQQKNLENQYENLLSLGKDRRDRLKDSVQAYQLVREAND 1878
+ P + + +N+ +L + + R RL D Q + L+ E +
Sbjct: 1535 QGHQPRIDDIFERSQNIVTDSSSLSA--EAIRQRLADLKQLWGLLIEETE 1582
Score = 149 bits (376), Expect = 3e-35
Identities = 96/386 (24%), Positives = 190/386 (49%), Gaps = 4/386 (1%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
ERR ++ L R+ + E WIA++E ++++G + V L + +F +
Sbjct: 1689 ERRGKLDERHRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTG 1748
Query: 187 -AQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQ 363
+E+ ++ +A++L+ +GH AA + + +D L A+L E R L S+
Sbjct: 1749 NIGQERVDTVNHLADELINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELH 1808
Query: 364 LFDRDADEIKAWIVEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVK---S 534
F DA EI I +K K +E ++ +++ + H F +I A ++ ++ +
Sbjct: 1809 KFYHDAKEIFGRIQDKHKKLPEELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAA 1868
Query: 535 RGQSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIW 714
R Q+ D K+DDIQ+R E+ + WK L+ A + + L + +F V D+ +W
Sbjct: 1869 RLQAAYAGD--KADDIQKRENEVLEAWKSLLDACESRRVRLVDTGDKFRFFSMVRDLMLW 1926
Query: 715 LAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDAD 894
+ +V Q+ + + +D++SV L H ++++I + D + ++ + H+ ++
Sbjct: 1927 MEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTTCIELGKSLLARKHYASE 1986
Query: 895 AIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVG 1074
IK+K +++ + ++ + E R L ++HQF RDA E W+ +EP S +G
Sbjct: 1987 EIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIG 2046
Query: 1075 RDLIGVQNLIKKHQAIQAEVTGHEPR 1152
+ + V+ LIK+H+A + + R
Sbjct: 2047 QSVDEVEKLIKRHEAFEKSAATWDER 2072
Score = 79.0 bits (193), Expect = 5e-14
Identities = 63/273 (23%), Positives = 126/273 (46%), Gaps = 4/273 (1%)
Frame = +1
Query: 37 DLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQRLD 216
+L FY D ++ I + L ++G ++VE L R H FE + A + ++L
Sbjct: 1806 ELHKFYHDAKEIFGRIQDKHKKLPE-ELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQ 1864
Query: 217 DIANKLVENGHYA---AADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADE 387
+ A +L YA A D+ K+ +++L +L + + R+ L D+ + F +
Sbjct: 1865 EDAARL--QAAYAGDKADDIQKRENEVLEAWKSLLDACESRRVRLVDTGDKFRFFSMVRD 1922
Query: 388 IKAWIVEKLKTA-SDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDH 564
+ W+ + ++ + E ++ ++++ + HQ AEI A G+SLL H
Sbjct: 1923 LMLWMEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTTCIELGKSLLARKH 1982
Query: 565 NKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGS 744
S++I++++ +L + K+++ + + L QF R+ E WL E L S
Sbjct: 1983 YASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSS 2042
Query: 745 DDCGKDLNSVTNLQKKHNLLESDISSHQDRIDS 843
+ G+ ++ V L K+H E ++ +R +
Sbjct: 2043 REIGQSVDEVEKLIKRHEAFEKSAATWDERFSA 2075
Score = 61.6 bits (148), Expect = 7e-09
Identities = 32/94 (34%), Positives = 52/94 (55%), Gaps = 1/94 (1%)
Frame = +1
Query: 1 WNERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKS 180
W +R +++ F RD AEAW+ QE +L + ++G S+D VE LI++HE FEKS
Sbjct: 2006 WEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIGQSVDEVEKLIKRHEAFEKS 2065
Query: 181 LAAQEEKTQRLDDIAN-KLVENGHYAAADVNKKR 279
A +E+ L+ + +L+E + K+R
Sbjct: 2066 AATWDERFSALERLTTLELLEVRRQQEEEERKRR 2099
Score = 58.5 bits (140), Expect = 6e-08
Identities = 65/264 (24%), Positives = 106/264 (40%), Gaps = 22/264 (8%)
Frame = +1
Query: 757 KDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNRYS 936
K N+ NLQ NL E + + L D V +H D +I + + +S
Sbjct: 226 KKSNAHYNLQNAFNLAEQHLG-----LTKLLDPEDISV--DHPDEKSIITYVVTYYHYFS 278
Query: 937 KLQEPLEKRK-------NKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQ 1095
K++ + K N + + ++ A D +WI + I + L+GVQ
Sbjct: 279 KMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQ 338
Query: 1096 NLIK---KHQAIQAEVTGHEPRILEVC--NEGQKMIDGNH--YANRDIEKKIDDMKNLWS 1254
++ ++ ++ E LEV KM N Y R+ K I D+ W
Sbjct: 339 QQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMpre-GKLISDINKAWE 397
Query: 1255 DLKNKADKRRQLLDDSLEAQQYLAD--------ASEAESWMREKEPLVGSTEFGKDEDST 1410
L+ +R L + L Q+ L A+ E+W+ E + LV FG D +
Sbjct: 398 RLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAV 457
Query: 1411 EALLKKHDALMADIEAYRSTIDSL 1482
EA KKH+A+ DI AY + ++
Sbjct: 458 EAATKKHEAIETDIAAYEERVQAV 481
>sp|Q00963|SPTCB_DROME Spectrin beta chain Length = 2291 Score = 292 bits (748), Expect = 2e-78 Identities = 164/497 (32%), Positives = 271/497 (54%), Gaps = 3/497 (0%) Frame = +1 Query: 1 WNERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKS 180 W R+ L Q++D QLF RD Q E +++QE FL +D +L+ E +++HE F + Sbjct: 1158 WENRQVLLSQSLDQQLFNRDARQTEVLLSQQEHFLSKDDTPVNLEQAENQLKRHEAFLTT 1217 Query: 181 LAAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNY 360 + A ++K L +A+ LVE H+ A + K+ +++ R+ + ++A + L++ Sbjct: 1218 MEANDDKINTLLQVADTLVEKDHFDADKIGKRAENITGRRDDNRQRALDQHEKLKNQVKL 1277 Query: 361 QLFDRDADEIKAWIVEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRG 540 F +D +E+ W+ EK T+ DE+Y+ + SK +HQ F AEIAAN+ R+ + + Sbjct: 1278 HEFLQDLEELAEWVQEKYATSQDESYRSAKTIHSKWTRHQAFEAEIAANKERLFEAEKSA 1337 Query: 541 QSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLA 720 Q L D I+ +++EL K + DL +K K L A+ + + +D++ ++ Sbjct: 1338 QELSKEKPEFKDVIEPKLKELAKQFDDLEVHTKEKGAMLFDANREVLVQQTCDDIDSYIT 1397 Query: 721 EVESQLGSDDCGKDLNSVTNLQKKHNLLESDIS---SHQDRIDSFLQQADQFVHDNHFDA 891 ++E Q+ S D DL SV L +K ++++ ++ + ID + + V + + Sbjct: 1398 DLEKQIVSGDTANDLTSVNILMQKQQVIQTQMAVKARQVEEIDKQTEYLQKTVPEEKIEP 1457 Query: 892 DAIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNV 1071 +KK V R+ K++ PL +R+ L + QF RD +DE+ WI EK P+A S + Sbjct: 1458 IVVKKTA--VLERFEKIKAPLLERQKALEKKKEAFQFCRDVEDEKLWIDEKLPVANSPDY 1515 Query: 1072 GRDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLW 1251 G L V L KK+Q++ E+ HEPRI +CN G+K+ID H + E I D+ W Sbjct: 1516 GNSLFNVHVLKKKNQSLATEIDNHEPRINAICNNGRKLIDEGHEDAKKFEALISDLTQKW 1575 Query: 1252 SDLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKH 1431 +LK+ + RR+ L +S + QQY DA EAESWM E+E + + GKDE S + L+KKH Sbjct: 1576 QELKDAIENRRKHLLESEKVQQYFFDAQEAESWMSEQELYMMVEDRGKDEISAQNLMKKH 1635 Query: 1432 DALMADIEAYRSTIDSL 1482 + L +E Y +TI L Sbjct: 1636 ENLEQSVEDYANTIRQL 1652
Score = 205 bits (521), Expect = 4e-52
Identities = 128/433 (29%), Positives = 236/433 (54%), Gaps = 13/433 (3%)
Frame = +1
Query: 259 ADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQL---FDRDADEIKAWIVEKLKTASD 429
+D+NK + L KA E + LR+ + QL FDR A + W+ E + S
Sbjct: 386 SDINKAWERL--EKAEHERELALREELIRQEKLEQLAARFDRKASMRETWLSENQRLVSQ 443
Query: 430 ENYK-EPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHNKSDDIQQRIEELD 606
+N+ + +++ +KH+ +I A E R+ V + L ++ I R + +
Sbjct: 444 DNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERYHDVKRILLRKDNVM 503
Query: 607 KLWK---DLVSASKIK-ETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDCGKDLNSV 774
+LW +L+ A +++ E +L Q+ + +++ME E++ L +DD GK L V
Sbjct: 504 RLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNME----EIKQLLMTDDYGKHLMGV 559
Query: 775 TNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNH-----FDADAIKKKQIEVCNRYSK 939
+L +KH+L+E+DI+ +R+ +Q + +F+ D+ D + I + ++ + Y++
Sbjct: 560 EDLLQKHSLVEADINILGERVKVVVQNSQKFLSDDPESYKPCDPEIIVSRVQQLEDAYAE 619
Query: 940 LQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKHQA 1119
L +R+++L ++ KL QFY D DEE+WI EKE I + VG DL V ++ KH+A
Sbjct: 620 LVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVNLMLSKHKA 679
Query: 1120 IQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLLDD 1299
+++E+T H+P++ V G ++I H+ I+ ++ ++ N W L + RRQ L++
Sbjct: 680 LESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDLTKYRRQRLEN 739
Query: 1300 SLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRSTIDS 1479
++E Q ADA + ++WM + +V S + G+DE + ++LLKKH + +++ Y ID+
Sbjct: 740 AVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADELKNYAEVIDA 799
Query: 1480 LRTQADACKMQEA 1518
L QA++ K+ EA
Sbjct: 800 LHKQAESLKLNEA 812
Score = 194 bits (494), Expect = 6e-49
Identities = 112/487 (22%), Positives = 245/487 (50%), Gaps = 2/487 (0%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
ERR E++ L FY DT E WI ++E + ++VG L +V ++ KH+ E +
Sbjct: 626 ERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVNLMLSKHKALESEIT 685
Query: 187 AQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQL 366
+ + + Q + + ++L+ GH+ A + + ++L + +L + K R+ LE++ Y
Sbjct: 686 SHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDLTKYRRQRLENAVEYFQ 745
Query: 367 FDRDADEIKAWIVEKLKTASDENY-KEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQ 543
DAD++ W+++ L+ S E+ ++ N+QS ++KH++ E+ ID + + +
Sbjct: 746 LFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADELKNYAEVIDALHKQAE 805
Query: 544 SLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAE 723
SL ++ K+ ++ +R+E +D +K+L +K+++ L A + + + +E W+ E
Sbjct: 806 SLKLNEAEKA-NVDKRLEAIDNRYKELTELAKLRKQRLLDALSLYKLMSEADGVEQWIKE 864
Query: 724 VESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIK 903
L + GKD+ V ++ + + +++++ R+ Q A Q +H H ++D I
Sbjct: 865 KTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMNANASRVAVVNQLARQLLHVEHPNSDEIL 924
Query: 904 KKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGST-NVGRD 1080
++Q + +S L+E E + + L A+ + FY + + WI +K+ I T ++ D
Sbjct: 925 ERQNHLNQEWSTLREKAEAKMDDLKSAHGVQTFYIECRETISWIEDKKRILTETDSLEMD 984
Query: 1081 LIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDL 1260
L GV L ++ + ++ + ++ + E + D + + I ++I ++ +W L
Sbjct: 985 LTGVMTLQRRLSGMDRDLAAIQAKLSSLEREANSIEDEHPEEAKIIRERIAQIELIWEQL 1044
Query: 1261 KNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDAL 1440
+R L+++ + ++L D ++W+ + + V S + E LL +H ++
Sbjct: 1045 TQMLKERDSKLEEAGDLHRFLRDLDHFQTWLTKTQTDVASEDTPTSLPEAEKLLNQHQSI 1104
Query: 1441 MADIEAY 1461
+I+ Y
Sbjct: 1105 REEIDNY 1111
Score = 194 bits (492), Expect = 1e-48
Identities = 127/506 (25%), Positives = 249/506 (49%), Gaps = 12/506 (2%)
Frame = +1
Query: 49 FYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQRLDDIAN 228
F R E W+++ + + ++ G L +VEA +KHE E + A EE+ Q + + +
Sbjct: 423 FDRKASMRETWLSENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCD 482
Query: 229 KLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDS----HNYQ--LFDRD-ADE 387
+L ++ + ++D+++ L E + R+ LE S N+Q L+ D +E
Sbjct: 483 ELESERYHDVKRILLRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEE 542
Query: 388 IKAWIVEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDHN 567
IK ++ +D+ K ++ +QKH A+I R+ V Q L D
Sbjct: 543 IKQLLM------TDDYGKHLMGVEDLLQKHSLVEADINILGERVKVVVQNSQKFLSDDPE 596
Query: 568 K-----SDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVES 732
+ I R+++L+ + +LV + + + L ++ QF + D E W+ E E
Sbjct: 597 SYKPCDPEIIVSRVQQLEDAYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQ 656
Query: 733 QLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQ 912
+ +D+ G DL +V + KH LES+I+SH ++ + + + + + HF AD IK +
Sbjct: 657 IVSTDEVGHDLTTVNLMLSKHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRL 716
Query: 913 IEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGV 1092
E+ N++ L + + R+ +L +A + Q + DADD ++W+ + I S +VGRD V
Sbjct: 717 KEILNKWDHLLDLTKYRRQRLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANV 776
Query: 1093 QNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKA 1272
Q+L+KKH+ + E+ + +++ ++ + + N +++K+++ + N + +L A
Sbjct: 777 QSLLKKHKDVADELKNYA-EVIDALHKQAESLKLNEAEKANVDKRLEAIDNRYKELTELA 835
Query: 1273 DKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADI 1452
R+Q L D+L + +++A E W++EK ++ + GKD + E + + + ++
Sbjct: 836 KLRKQRLLDALSLYKLMSEADGVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEM 895
Query: 1453 EAYRSTIDSLRTQADACKMQEAPVSD 1530
A S + + A E P SD
Sbjct: 896 NANASRVAVVNQLARQLLHVEHPNSD 921
Score = 192 bits (487), Expect = 4e-48
Identities = 134/508 (26%), Positives = 245/508 (48%), Gaps = 4/508 (0%)
Frame = +1
Query: 19 LYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEE 198
L++ N ++ L + + +++I E + + D + L SV L++K + + +A +
Sbjct: 1376 LFDANREV-LVQQTCDDIDSYITDLEKQIVSGDTANDLTSVNILMQKQQVIQTQMAVKAR 1434
Query: 199 KTQRLDDIANKLVENGHYAAAD-VNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDR 375
+ + +D L + + + K+ +L R ++ R+ +LE F R
Sbjct: 1435 QVEEIDKQTEYLQKTVPEEKIEPIVVKKTAVLERFEKIKAPLLERQKALEKKKEAFQFCR 1494
Query: 376 DADEIKAWIVEKLKTASDENYKEPT-NLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLL 552
D ++ K WI EKL A+ +Y N+ +K+Q+ EI +E RI+ + + G+ L+
Sbjct: 1495 DVEDEKLWIDEKLPVANSPDYGNSLFNVHVLKKKNQSLATEIDNHEPRINAICNNGRKLI 1554
Query: 553 DSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVES 732
D H + + I +L + W++L A + + +L ++ QQ+ + ++ E W++E E
Sbjct: 1555 DEGHEDAKKFEALISDLTQKWQELKDAIENRRKHLLESEKVQQYFFDAQEAESWMSEQEL 1614
Query: 733 QLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQ 912
+ +D GKD S NL KKH LE + + + I + A QF D+ DA+ KQ
Sbjct: 1615 YMMVEDRGKDEISAQNLMKKHENLEQSVEDYANTIRQLGEVARQFSGDDISSGDAVAVKQ 1674
Query: 913 IEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGV 1092
++ Y+ L++ +R+ +LN+A +L R+ DD E WI ++E +AGS +G+D V
Sbjct: 1675 SQLDKLYAGLKDLAGERRARLNEALQLFMLSREVDDLEQWITDREVVAGSQELGQDFDHV 1734
Query: 1093 QNLIKKHQ--AIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKN 1266
L ++ A E G E R+ +V +I H + I + D++ W DL
Sbjct: 1735 TLLSERFNEFARDTEAVGGE-RVAKVNGIADNLIQAGHSDSATIAEWKDNLNESWQDLLE 1793
Query: 1267 KADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMA 1446
+ R Q+L S E ++ D + + EK+ V S E G+D S L +KH +
Sbjct: 1794 LIETRTQMLAASRELHKFFHDCKDVLGRILEKQHGV-SDELGRDAGSVSTLQRKHYNFLQ 1852
Query: 1447 DIEAYRSTIDSLRTQADACKMQEAPVSD 1530
D+ S + + Q ++ K+Q+A D
Sbjct: 1853 DLITLYSQVQQI--QEESAKLQDAYAGD 1878
Score = 178 bits (451), Expect = 5e-44
Identities = 123/499 (24%), Positives = 241/499 (48%), Gaps = 6/499 (1%)
Frame = +1
Query: 4 NERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSL 183
N R+ L E Q F+ D ++AE+W+++QE ++ D G S + L++KHE+ E+S+
Sbjct: 1584 NRRKHLLESEKVQQYFF-DAQEAESWMSEQELYMMVEDRGKDEISAQNLMKKHENLEQSV 1642
Query: 184 AAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQ 363
++L ++A + + + V K+ L A L++ A R+ L ++
Sbjct: 1643 EDYANTIRQLGEVARQFSGDDISSGDAVAVKQSQLDKLYAGLKDLAGERRARLNEALQLF 1702
Query: 364 LFDRDADEIKAWIVEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEG--RIDDVKSR 537
+ R+ D+++ WI ++ A + + + + + + N A G R+ V
Sbjct: 1703 MLSREVDDLEQWITDREVVAGSQELGQDFDHVTLLSERFNEFARDTEAVGGERVAKVNGI 1762
Query: 538 GQSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWL 717
+L+ + H+ S I + + L++ W+DL+ + + L + +F + +D+ +
Sbjct: 1763 ADNLIQAGHSDSATIAEWKDNLNESWQDLLELIETRTQMLAASRELHKFFHDCKDVLGRI 1822
Query: 718 AEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQA----DQFVHDNHF 885
E + + SD+ G+D SV+ LQ+KH D+ + ++ +++ D + D
Sbjct: 1823 LEKQHGV-SDELGRDAGSVSTLQRKHYNFLQDLITLYSQVQQIQEESAKLQDAYAGDK-- 1879
Query: 886 DADAIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGST 1065
A I ++ EV + + LQ + RK KL D L +F+ W+ + ++
Sbjct: 1880 -AKEITNREQEVLHAWDNLQAMCDARKQKLADTGDLFRFFNMVRILMIWMEDLVRQMNTS 1938
Query: 1066 NVGRDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKN 1245
RD+ GV+ L+ HQ+++AE+ E + G++++ NHYA+ DI+ ++ + N
Sbjct: 1939 EKPRDVSGVELLMNNHQSLKAEIDTREDNFGACISLGKELLTRNHYASADIKDRLMTLSN 1998
Query: 1246 LWSDLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLK 1425
+ L + ++R + L LE Q+ DA+ AE+W+ +EP + S+E G D E L+K
Sbjct: 1999 SRNALLRRWEERWENLQLILEVYQFARDAAVAEAWLIAQEPYLLSSELGHTIDEVENLIK 2058
Query: 1426 KHDALMADIEAYRSTIDSL 1482
KH+A A +L
Sbjct: 2059 KHEAFEKSAAAQEERFSAL 2077
Score = 160 bits (405), Expect = 1e-38
Identities = 115/486 (23%), Positives = 234/486 (48%), Gaps = 8/486 (1%)
Frame = +1
Query: 25 EQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVG-DSLDSVEALIRKHEDFEKSLAAQEEK 201
+ + L F +D E+ W+ QE + + D S ++ + +H+ FE +AA +E+
Sbjct: 1272 KNQVKLHEFLQDLEELAEWV--QEKYATSQDESYRSAKTIHSKWTRHQAFEAEIAANKER 1329
Query: 202 TQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDA 381
+ A +L + + K +L + +LE K + L D++ L +
Sbjct: 1330 LFEAEKSAQELSKEKPEFKDVIEPKLKELAKQFDDLEVHTKEKGAMLFDANREVLVQQTC 1389
Query: 382 DEIKAWIVEKLKT-ASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDS 558
D+I ++I + K S + + T++ +QK Q ++A +++++ + + L +
Sbjct: 1390 DDIDSYITDLEKQIVSGDTANDLTSVNILMQKQQVIQTQMAVKARQVEEIDKQTEYLQKT 1449
Query: 559 -DHNKSDDIQQR----IEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAE 723
K + I + +E +K+ L+ K E + QF R+VED ++W+ E
Sbjct: 1450 VPEEKIEPIVVKKTAVLERFEKIKAPLLERQKALE----KKKEAFQFCRDVEDEKLWIDE 1505
Query: 724 VESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIK 903
S D G L +V L+KK+ L ++I +H+ RI++ + + + H DA +
Sbjct: 1506 KLPVANSPDYGNSLFNVHVLKKKNQSLATEIDNHEPRINAICNNGRKLIDEGHEDAKKFE 1565
Query: 904 KKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDL 1083
++ ++ +L++ +E R+ L ++ K+ Q++ DA + E W+ E+E + G+D
Sbjct: 1566 ALISDLTQKWQELKDAIENRRKHLLESEKVQQYFFDAQEAESWMSEQELYMMVEDRGKDE 1625
Query: 1084 IGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRD-IEKKIDDMKNLWSDL 1260
I QNL+KKH+ ++ V + I ++ E + G+ ++ D + K + L++ L
Sbjct: 1626 ISAQNLMKKHENLEQSVEDYANTIRQL-GEVARQFSGDDISSGDAVAVKQSQLDKLYAGL 1684
Query: 1261 KNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDAL 1440
K+ A +RR L+++L+ + + E W+ ++E + GS E G+D D L ++ +
Sbjct: 1685 KDLAGERRARLNEALQLFMLSREVDDLEQWITDREVVAGSQELGQDFDHVTLLSERFNEF 1744
Query: 1441 MADIEA 1458
D EA
Sbjct: 1745 ARDTEA 1750
Score = 155 bits (391), Expect = 5e-37
Identities = 117/515 (22%), Positives = 230/515 (44%), Gaps = 16/515 (3%)
Frame = +1
Query: 1 WNERRFLYEQNMD-------LQLFYRDTEQAEAWIAKQEAFL-ENNDVGDSLDSVEALIR 156
W+ R E MD +Q FY + + +WI ++ L E + + L V L R
Sbjct: 934 WSTLREKAEAKMDDLKSAHGVQTFYIECRETISWIEDKKRILTETDSLEMDLTGVMTLQR 993
Query: 157 KHEDFEKSLAAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKG 336
+ ++ LAA + K L+ AN + + A + ++ + + L + K R
Sbjct: 994 RLSGMDRDLAAIQAKLSSLEREANSIEDEHPEEAKIIRERIAQIELIWEQLTQMLKERDS 1053
Query: 337 SLEDSHNYQLFDRDADEIKAWIVEKLKTASDENYKEPTNL---QSKVQKHQNFLAEIAAN 507
LE++ + F RD D + W+ + + E+ PT+L + + +HQ+ EI
Sbjct: 1054 KLEEAGDLHRFLRDLDHFQTWLTKTQTDVASED--TPTSLPEAEKLLNQHQSIREEIDNY 1111
Query: 508 EGRIDDVKSRGQSLLDSDHNKSDD-----IQQRIEELDKLWKDLVSASKIKETNLTQASG 672
++ G+ L S+ + SDD +++R+ L W++L + ++ L+Q+
Sbjct: 1112 TEDYKNMMEYGERLT-SEGSTSDDPQYMFLRERLNALKDGWEELHQMWENRQVLLSQSLD 1170
Query: 673 QQQFIRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQ 852
QQ F R+ E+ L++ E L DD +L N K+H + + ++ D+I++ LQ
Sbjct: 1171 QQLFNRDARQTEVLLSQQEHFLSKDDTPVNLEQAENQLKRHEAFLTTMEANDDKINTLLQ 1230
Query: 853 QADQFVHDNHFDADAIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDW 1032
AD V +HFDAD I K+ + R ++ + KL + KLH+F +D ++ +W
Sbjct: 1231 VADTLVEKDHFDADKIGKRAENITGRRDDNRQRALDQHEKLKNQVKLHEFLQDLEELAEW 1290
Query: 1033 IHEKEPIAGSTNVGRDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANR 1212
+ EK + + R + + +HQA +AE+ ++ R+ E Q++
Sbjct: 1291 VQEKYATSQDESY-RSAKTIHSKWTRHQAFEAEIAANKERLFEAEKSAQELSKEKPEFKD 1349
Query: 1213 DIEKKIDDMKNLWSDLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFG 1392
IE K+ ++ + DL+ ++ +L D+ + +S++ + E + S +
Sbjct: 1350 VIEPKLKELAKQFDDLEVHTKEKGAMLFDANREVLVQQTCDDIDSYITDLEKQIVSGDTA 1409
Query: 1393 KDEDSTEALLKKHDALMADIEAYRSTIDSLRTQAD 1497
D S L++K + + ++ + Q +
Sbjct: 1410 NDLTSVNILMQKQQVIQTQMAVKARQVEEIDKQTE 1444
Score = 150 bits (378), Expect = 2e-35
Identities = 109/490 (22%), Positives = 222/490 (45%), Gaps = 2/490 (0%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSL- 183
ERR + + L + R+ + E WI +E + ++G D V L + +F +
Sbjct: 1690 ERRARLNEALQLFMLSREVDDLEQWITDREVVAGSQELGQDFDHVTLLSERFNEFARDTE 1749
Query: 184 AAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQ 363
A E+ +++ IA+ L++ GH +A + + +D+L +L E + R L S
Sbjct: 1750 AVGGERVAKVNGIADNLIQAGHSDSATIAEWKDNLNESWQDLLELIETRTQMLAASRELH 1809
Query: 364 LFDRDADEIKAWIVEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQ 543
F D ++ I+EK SDE ++ ++ + +KH NFL ++ ++ ++
Sbjct: 1810 KFFHDCKDVLGRILEKQHGVSDELGRDAGSVSTLQRKHYNFLQDLITLYSQVQQIQEESA 1869
Query: 544 SLLDS-DHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLA 720
L D+ +K+ +I R +E+ W +L + ++ L +F V + IW+
Sbjct: 1870 KLQDAYAGDKAKEITNREQEVLHAWDNLQAMCDARKQKLADTGDLFRFFNMVRILMIWME 1929
Query: 721 EVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAI 900
++ Q+ + + +D++ V L H L+++I + +D + + + + NH+ + I
Sbjct: 1930 DLVRQMNTSEKPRDVSGVELLMNNHQSLKAEIDTREDNFGACISLGKELLTRNHYASADI 1989
Query: 901 KKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRD 1080
K + + + N + L E+R L +++QF RDA E W+ +EP S+ +G
Sbjct: 1990 KDRLMTLSNSRNALLRRWEERWENLQLILEVYQFARDAAVAEAWLIAQEPYLLSSELGHT 2049
Query: 1081 LIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDL 1260
+ V+NLIKKH+A + E R + R ++ +MK +L
Sbjct: 2050 IDEVENLIKKHEAFEKSAAAQEERFSAL--------------ERLTTFELKEMKRR-QEL 2094
Query: 1261 KNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDAL 1440
+A+++R + +A A+ ++ E+ R+ + VG++ + T + H+
Sbjct: 2095 AEEAERQRIKEEQEAKAASEAAEQAKREAERRD-DVDVGASHDDSERGGTPGAGEGHEGY 2153
Query: 1441 MADIEAYRST 1470
+ + ST
Sbjct: 2154 VTRKHEWDST 2163
Score = 139 bits (349), Expect = 4e-32
Identities = 123/561 (21%), Positives = 260/561 (46%), Gaps = 53/561 (9%)
Frame = +1
Query: 352 HNYQLFDRDADEIKAWIVEKLKTASDENYKEP-TNLQSKVQKHQNFLA----EIAANEGR 516
H+Y+ F D + WI +++ + ++ +Q ++ + N+ +G
Sbjct: 301 HDYENFTSD---LLKWIETTIQSLGEREFENSLAGVQGQLAQFSNYRTIEKPPKFVEKGN 357
Query: 517 IDDVKSRGQSLLDSDHNKSDDIQQ--RIEELDKLWKDLVSASKIKETNLTQASGQQQ--- 681
++ + QS + +++ K ++ I +++K W+ L A +E L + +Q+
Sbjct: 358 LEVLLFTLQSKMRANNQKPYTPKEGKMISDINKAWERLEKAEHERELALREELIRQEKLE 417
Query: 682 -----FIRNVEDMEIWLAEVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSF 846
F R E WL+E + + D+ G DL +V KKH +E+DI ++++R+ +
Sbjct: 418 QLAARFDRKASMRETWLSENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAV 477
Query: 847 LQQADQFVHDNHFDADAIKKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEE 1026
+ D+ + + D I ++ V ++ L E L R+ +L + +L Q +++
Sbjct: 478 VAVCDELESERYHDVKRILLRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYIL 537
Query: 1027 DWIHEKEPIAGSTNVGRDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMI--DGNH 1200
D + E + + + + G+ L+GV++L++KH ++A++ R+ V QK + D
Sbjct: 538 DNMEEIKQLLMTDDYGKHLMGVEDLLQKHSLVEADINILGERVKVVVQNSQKFLSDDPES 597
Query: 1201 YANRDIE---KKIDDMKNLWSDLKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPL 1371
Y D E ++ +++ +++L A +RR L++S + Q+ D ++ E+W++EKE +
Sbjct: 598 YKPCDPEIIVSRVQQLEDAYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQI 657
Query: 1372 VGSTEFGKDEDSTEALLKKHDALMADIEAYRSTIDSLRTQ-----------ADACKMQEA 1518
V + E G D + +L KH AL ++I ++ + ++ AD K +
Sbjct: 658 VSTDEVGHDLTTVNLMLSKHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLK 717
Query: 1519 PVSDSYGKETVMALYDYQE-----------KNpreVSMRKGDVLTLLNSNHKDWWKVEIN 1665
+ + + + Y Q + +V D L +++S +D + E N
Sbjct: 718 EILNKWDHLLDLTKYRRQRLENAVEYFQLFADADDVDNWMLDTLRIVSS--EDVGRDEAN 775
Query: 1666 DR---QGHVPAA-----YVKKVDAMMSDIDP---NAPEQITVASQQKNLENQYENLLSLG 1812
+ + H A Y + +DA+ + N E+ V + + ++N+Y+ L L
Sbjct: 776 VQSLLKKHKDVADELKNYAEVIDALHKQAESLKLNEAEKANVDKRLEAIDNRYKELTELA 835
Query: 1813 KDRRDRLKDSVQAYQLVREAN 1875
K R+ RL D++ Y+L+ EA+
Sbjct: 836 KLRKQRLLDALSLYKLMSEAD 856
Score = 65.5 bits (158), Expect = 5e-10
Identities = 32/72 (44%), Positives = 47/72 (65%)
Frame = +1
Query: 1 WNERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKS 180
W ER + +++ F RD AEAW+ QE +L ++++G ++D VE LI+KHE FEKS
Sbjct: 2007 WEERWENLQLILEVYQFARDAAVAEAWLIAQEPYLLSSELGHTIDEVENLIKKHEAFEKS 2066
Query: 181 LAAQEEKTQRLD 216
AAQEE+ L+
Sbjct: 2067 AAAQEERFSALE 2078
>sp|Q9QWN8|SPTN2_RAT Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin) (SPNB-3) (Beta SpIII sigma 1) (Spectrin-like protein GTRAP41) Length = 2388 Score = 286 bits (733), Expect = 1e-76 Identities = 168/509 (33%), Positives = 277/509 (54%) Frame = +1 Query: 1 WNERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKS 180 W R+ Q Q F RD QAE ++ QE FL + ++ +L + +A I+K EDF + Sbjct: 1161 WESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYFLSHTEMPGTLQAADAAIKKLEDFMST 1220 Query: 181 LAAQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNY 360 + A E+ + L + +LV G+ A + +K D + R +E + G L D+ Sbjct: 1221 MDANGERIRGLLEAGRQLVSKGNIHAEKIQEKADSIEKRHRKNQEAVQQLLGRLRDNREQ 1280 Query: 361 QLFDRDADEIKAWIVEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRG 540 Q F +D E+K WI EK+ TA D +Y E NL +K QKHQ F+AE+AAN+ +D V G Sbjct: 1281 QHFLQDCQELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQAFMAELAANKDWLDKVDKEG 1340 Query: 541 QSLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLA 720 + L + +++E+L + W +L + ++ K +L A+ + F ++ +E WL Sbjct: 1341 RELTLEKPELKVLVSEKLEDLHRRWDELETTTQAKARSLFDANRAELFAQSCSALESWLE 1400 Query: 721 EVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAI 900 +++QL SDD GKDL SV L KK +LE +++ + +++ QA ++ A + Sbjct: 1401 SLQAQLHSDDYGKDLTSVNILLKKQQMLEREMAVREKEVEAIQAQAKALAQEDQ-SAGEV 1459 Query: 901 KKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRD 1080 ++ V ++ L +P++ R +L + + HQF+RD +DE W+ E+ P+A S G+D Sbjct: 1460 ERTSRAVEEKFRALCQPMKDRCRRLQASREQHQFHRDVEDEILWVTERLPMASSLEHGKD 1519 Query: 1081 LIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDL 1260 L VQ L+KK+Q +Q E+ GHEPRI ++ E Q+ + G A ++ +++ +W L Sbjct: 1520 LPSVQLLMKKNQTLQKEIQGHEPRIADL-KERQRTL-GTAAAGPELA----ELQEMWKRL 1573 Query: 1261 KNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDAL 1440 ++ + R + L+++L AQQ+ DA+EAE+WM E+E + E KDE S +A +KKH L Sbjct: 1574 SHELELRGKRLEEALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDELSAQAEVKKHQVL 1633 Query: 1441 MADIEAYRSTIDSLRTQADACKMQEAPVS 1527 + Y TI L + E P S Sbjct: 1634 EQALADYAQTIKQLAASSQDMIDHEHPES 1662
Score = 185 bits (469), Expect = 4e-46
Identities = 134/508 (26%), Positives = 243/508 (47%), Gaps = 2/508 (0%)
Frame = +1
Query: 13 RFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQ 192
R L++ N +LF + E+W+ +A L ++D G L SV L++K + E+ +A +
Sbjct: 1377 RSLFDANR-AELFAQSCSALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEREMAVR 1435
Query: 193 EEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFD 372
E++ + + A L + +A +V + + + L + K R L+ S F
Sbjct: 1436 EKEVEAIQAQAKALAQEDQ-SAGEVERTSRAVEEKFRALCQPMKDRCRRLQASREQHQFH 1494
Query: 373 RDADEIKAWIVEKLKTASD-ENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSL 549
RD ++ W+ E+L AS E+ K+ ++Q ++K+Q EI +E RI D+K R ++L
Sbjct: 1495 RDVEDEILWVTERLPMASSLEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLKERQRTL 1554
Query: 550 LDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVE 729
+ + EL ++WK L +++ L +A QQF R+ + E W+ E E
Sbjct: 1555 GTAAAGPE------LAELQEMWKRLSHELELRGKRLEEALRAQQFYRDAAEAEAWMGEQE 1608
Query: 730 SQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKK 909
+ + KD S KKH +LE ++ + I + + H ++ + +
Sbjct: 1609 LHMMGQEKAKDELSAQAEVKKHQVLEQALADYAQTIKQLAASSQDMIDHEHPESTRLTIR 1668
Query: 910 QIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIG 1089
Q +V Y+ L+E +R+ +L + +L Q R+ DD E WI E+E +A S +G+D
Sbjct: 1669 QAQVDKLYAGLKELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEH 1728
Query: 1090 VQNLIKKHQAIQAEV-TGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKN 1266
V L K + + T + R+ +I G H A + + D + W+DL
Sbjct: 1729 VTMLRDKFREFSRDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLE 1788
Query: 1267 KADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMA 1446
D R Q+L + E Q++L A +A + ++ K+ + G+D ++ EAL ++H A
Sbjct: 1789 LLDTRGQVLAAAYELQRFLHGARQALARVQHKQQQLPDGT-GRDLNAAEALQRRHCAYEH 1847
Query: 1447 DIEAYRSTIDSLRTQADACKMQEAPVSD 1530
DI+A + + + Q D ++Q+A D
Sbjct: 1848 DIQALSTQVQ--QVQDDGLRLQKAYAGD 1873
Score = 178 bits (451), Expect = 5e-44
Identities = 130/496 (26%), Positives = 233/496 (46%), Gaps = 22/496 (4%)
Frame = +1
Query: 79 WIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQR------LDDIANKLVE 240
WI + L + + +SL V+ ++ + +++ + T++ L I +KL
Sbjct: 320 WIEQTIVTLNDRQLANSLSGVQNQLQSFNSY-RTVEKPPKFTEKGNLEVLLFTIQSKLRA 378
Query: 241 NGHYA--------AADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQL---FDRDADE 387
N +D+NK + L KA E + LR + QL FDR A
Sbjct: 379 NNQKVYTpreGRLISDINKAWERL--EKAEHERELALRTELIRQEKLEQLAARFDRKAAM 436
Query: 388 IKAWIVEKLKTASDENYK-EPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLDSDH 564
+ W+ E + S +N+ E +++ V+KH+ +I A GR+ V + L +
Sbjct: 437 RETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGRVQAVDAVAAELAAEHY 496
Query: 565 NKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGS 744
+ I R + +LW L + L Q+ +++ + W+AE++ +L S
Sbjct: 497 HDIKRIAARQNNVARLWDFLREMVAARRERLLLNLELQKVFQDLLYLMDWMAEMKGRLQS 556
Query: 745 DDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNH----FDADAIKKKQ 912
D GK L V +L + H L+E+DI+ +R+ + A +F D + ++
Sbjct: 557 QDLGKHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCDPGKEYRPCDPQLVSERV 616
Query: 913 IEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGV 1092
+ Y L E R+ +L ++ +L +F + + E W+ E++ + S GRDL GV
Sbjct: 617 ATLEQSYEALCELAATRRARLEESRRLWRFLWEVGEAEAWVREQQHLLASAETGRDLTGV 676
Query: 1093 QNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKA 1272
L+ KH A++ E++G + +GQ+++ H + +++ W L+ A
Sbjct: 677 LRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGANQASTRAAELQAQWERLEALA 736
Query: 1273 DKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADI 1452
++R Q L + Q+ ADA++ E+W+ + LV S E G DE ST+AL ++H AL +I
Sbjct: 737 EERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPEVGHDEFSTQALARQHRALEEEI 796
Query: 1453 EAYRSTIDSLRTQADA 1500
A+R T+D+LR QA A
Sbjct: 797 RAHRPTLDALREQAAA 812
Score = 161 bits (407), Expect = 7e-39
Identities = 117/494 (23%), Positives = 223/494 (45%), Gaps = 8/494 (1%)
Frame = +1
Query: 25 EQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKT 204
E+ + Q FYRD +AEAW+ +QE + + S +A ++KH+ E++LA +
Sbjct: 1585 EEALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDELSAQAEVKKHQVLEQALADYAQTI 1644
Query: 205 QRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDAD 384
++L + ++++ H + + ++ + A L+E A R+ L++ R+ D
Sbjct: 1645 KQLAASSQDMIDHEHPESTRLTIRQAQVDKLYAGLKELAGERRERLQEHLRLCQLRRELD 1704
Query: 385 EIKAWIVEKLKTASD----ENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLL 552
+++ WI E+ A+ ++Y+ T L+ K ++ + I + R+D + L+
Sbjct: 1705 DLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFSRDTSTIG--QERVDSANALANGLI 1762
Query: 553 DSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVES 732
H + + + L++ W DL+ + L A Q+F+ + +
Sbjct: 1763 AGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAAYELQRFLHGARQALARVQHKQQ 1822
Query: 733 QLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRI----DSFLQQADQFVHDNHFDADAI 900
QL D G+DLN+ LQ++H E DI + ++ D L+ + D A+ I
Sbjct: 1823 QL-PDGTGRDLNAAEALQRRHCAYEHDIQALSTQVQQVQDDGLRLQKAYAGDK---AEEI 1878
Query: 901 KKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRD 1080
+ V +++LQ R+ L D +F++ + W+ + RD
Sbjct: 1879 GRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELMLWMDGINLQMDAQERPRD 1938
Query: 1081 LIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDL 1260
+ +IK Q I+AE+ R + GQ+++ NHYA +I +K+ +++ +
Sbjct: 1939 VSSADLVIKNQQGIKAEIEARADRFSACIDMGQELLARNHYAAEEISEKLSQLQSRRQET 1998
Query: 1261 KNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDAL 1440
K ++ L LE + DA AE+W+ +EPLV S E G D E+L+K+H+A
Sbjct: 1999 AEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAELGCTVDEVESLIKRHEAF 2058
Query: 1441 MADIEAYRSTIDSL 1482
A+ +L
Sbjct: 2059 QKSAVAWEERFSAL 2072
Score = 158 bits (400), Expect = 4e-38
Identities = 109/499 (21%), Positives = 224/499 (44%), Gaps = 5/499 (1%)
Frame = +1
Query: 49 FYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQRLDDIAN 228
F R E W+++ + + ++ G L +VEA +RKHE E + A + Q +D +A
Sbjct: 430 FDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGRVQAVDAVAA 489
Query: 229 KLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEIKAWIVE 408
+L ++ + +++++ L E R+ L + Q +D + W+ E
Sbjct: 490 ELAAEHYHDIKRIAARQNNVARLWDFLREMVAARRERLLLNLELQKVFQDLLYLMDWMAE 549
Query: 409 -KLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLD--SDHNKSDD 579
K + S + K ++ +Q H+ A+IA R+ V + D ++ D
Sbjct: 550 MKGRLQSQDLGKHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCDPGKEYRPCDP 609
Query: 580 --IQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGSDDC 753
+ +R+ L++ ++ L + + L ++ +F+ V + E W+ E + L S +
Sbjct: 610 QLVSERVATLEQSYEALCELAATRRARLEESRRLWRFLWEVGEAEAWVREQQHLLASAET 669
Query: 754 GKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVCNRY 933
G+DL V L KH L ++S + L+Q Q V + H A+ + E+ ++
Sbjct: 670 GRDLTGVLRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGANQASTRAAELQAQW 729
Query: 934 SKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKH 1113
+L+ E+R +L A L+QF DA+D E W+ + + S VG D Q L ++H
Sbjct: 730 ERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPEVGHDEFSTQALARQH 789
Query: 1114 QAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLL 1293
+A++ E+ H P L+ E + +++ ++ ++ + +L+ +A +R + L
Sbjct: 790 RALEEEIRAHRP-TLDALREQAAALPPALSHTPEVQGRVPTLEQHYEELQARAGERARAL 848
Query: 1294 DDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRSTI 1473
+ +L L++A W+ EKE + + + E + ++ + L ++ A + +
Sbjct: 849 EAALAFYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPEMNALAARV 908
Query: 1474 DSLRTQADACKMQEAPVSD 1530
++ A+ P D
Sbjct: 909 TAVSDIAEQLLKASPPGKD 927
Score = 158 bits (399), Expect = 6e-38
Identities = 117/496 (23%), Positives = 221/496 (44%), Gaps = 6/496 (1%)
Frame = +1
Query: 31 NMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQR 210
N++LQ ++D W+A+ + L++ D+G L VE L++ HE E +A Q E+ +
Sbjct: 530 NLELQKVFQDLLYLMDWMAEMKGRLQSQDLGKHLAGVEDLLQLHELVEADIAVQAERVRA 589
Query: 211 LDDIANKLVENG-HYAAADVNKKRDDLLIRKANLE---EKAKLRKGSLEDSHNYQLFDRD 378
+ A + + G Y D + + + + E E A R+ LE+S F +
Sbjct: 590 VSASALRFCDPGKEYRPCDPQLVSERVATLEQSYEALCELAATRRARLEESRRLWRFLWE 649
Query: 379 ADEIKAWIVEKLK-TASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLLD 555
E +AW+ E+ AS E ++ T + + KH E++ G + +GQ L+
Sbjct: 650 VGEAEAWVREQQHLLASAETGRDLTGVLRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVA 709
Query: 556 SDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQ 735
H ++ R EL W+ L + ++ + L QA+ QF + DME WL +
Sbjct: 710 EGHPGANQASTRAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRL 769
Query: 736 LGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQI 915
+ S + G D S L ++H LE +I +H+ +D+ +QA + ++ +
Sbjct: 770 VSSPEVGHDEFSTQALARQHRALEEEIRAHRPTLDALREQAAALPPALSHTPE-VQGRVP 828
Query: 916 EVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQ 1095
+ Y +LQ +R L A + +A W+ EKE + L ++
Sbjct: 829 TLEQHYEELQARAGERARALEAALAFYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLE 888
Query: 1096 NLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKAD 1275
+ ++ + ++ E+ R+ V + ++++ + I + + W ++ AD
Sbjct: 889 VVQQRFETLEPEMNALAARVTAVSDIAEQLLKASPPGKDRIIGTQEQLNQRWQQFRSLAD 948
Query: 1276 KRRQLLDDSLEAQQYLADASEAESWMREKEPLVGST-EFGKDEDSTEALLKKHDALMADI 1452
++ L +L Q Y + +E ++WMREK ++ ST + G D AL +K D+
Sbjct: 949 GKKAALTSALSIQNYHLECTETQAWMREKTKVIESTQDLGNDLAGVLALQRKLAGTERDL 1008
Query: 1453 EAYRSTIDSLRTQADA 1500
EA + + L +A+A
Sbjct: 1009 EAISARVGELTQEANA 1024
Score = 150 bits (380), Expect = 9e-36
Identities = 113/497 (22%), Positives = 225/497 (45%), Gaps = 3/497 (0%)
Frame = +1
Query: 34 MDLQLFYRDTEQAEAWIAKQEAFLENN-DVGDSLDSVEALIRKHEDFEKSLAAQEEKTQR 210
+ +Q ++ + + +AW+ ++ +E+ D+G+ L V AL RK E+ L A +
Sbjct: 958 LSIQNYHLECTETQAWMREKTKVIESTQDLGNDLAGVLALQRKLAGTERDLEAISARVGE 1017
Query: 211 LDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLFDRDADEI 390
L AN L A +N + ++ +L + R+ SL ++ Q F R D+
Sbjct: 1018 LTQEANALAAGHPAQAPAINTRLGEVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDF 1077
Query: 391 KAWIVE-KLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQSLL-DSDH 564
+AW+ + AS+E ++ + +H E+ + +++ G+ + D
Sbjct: 1078 QAWLGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRTLGEEVTRDQAD 1137
Query: 565 NKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLGS 744
+ ++QR+E L W++L + ++ L QA G Q F+R+ E L+ E L
Sbjct: 1138 PQCLFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYFLSH 1197
Query: 745 DDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIEVC 924
+ L + KK S + ++ +RI L+ Q V + A+ I++K +
Sbjct: 1198 TEMPGTLQAADAAIKKLEDFMSTMDANGERIRGLLEAGRQLVSKGNIHAEKIQEKADSIE 1257
Query: 925 NRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLI 1104
R+ K QE +++ +L D + F +D + + WI EK A + + +
Sbjct: 1258 KRHRKNQEAVQQLLGRLRDNREQQHFLQDCQELKLWIDEKMLTAQDVSYD-EARNLHTKW 1316
Query: 1105 KKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRR 1284
+KHQA AE+ ++ + +V EG+++ + +K++D+ W +L+ +
Sbjct: 1317 QKHQAFMAELAANKDWLDKVDKEGRELTLEKPELKVLVSEKLEDLHRRWDELETTTQAKA 1376
Query: 1285 QLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYR 1464
+ L D+ A+ + S ESW+ + + S ++GKD S LLKK L ++
Sbjct: 1377 RSLFDANRAELFAQSCSALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEREMAVRE 1436
Query: 1465 STIDSLRTQADACKMQE 1515
+++++ QA A ++
Sbjct: 1437 KEVEAIQAQAKALAQED 1453
Score = 150 bits (379), Expect = 1e-35
Identities = 115/535 (21%), Positives = 242/535 (45%), Gaps = 2/535 (0%)
Frame = +1
Query: 10 RRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAA 189
RR E++ L F + +AEAW+ +Q+ L + + G L V L+ KH ++
Sbjct: 633 RRARLEESRRLWRFLWEVGEAEAWVREQQHLLASAETGRDLTGVLRLLNKHTALRGEMSG 692
Query: 190 QEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQLF 369
+ + + +LV GH A + + +L + LE A+ R L + + F
Sbjct: 693 RLGPLKLTLEQGQQLVAEGHPGANQASTRAAELQAQWERLEALAEERAQRLAQAASLYQF 752
Query: 370 DRDADEIKAWIVEKLK-TASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQS 546
DA++++AW+V+ L+ +S E + + Q+ ++H+ EI A+ +D ++ + +
Sbjct: 753 QADANDMEAWLVDALRLVSSPEVGHDEFSTQALARQHRALEEEIRAHRPTLDALREQAAA 812
Query: 547 LLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEV 726
L + + + ++Q R+ L++ +++L + + + L A + +W+ E
Sbjct: 813 LPPA-LSHTPEVQGRVPTLEQHYEELQARAGERARALEAALAFYTMLSEAGACGLWVEEK 871
Query: 727 ESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKK 906
E L + L + +Q++ LE ++++ R+ + A+Q + + D I
Sbjct: 872 EQWLNGLALPERLEDLEVVQQRFETLEPEMNALAARVTAVSDIAEQLLKASPPGKDRIIG 931
Query: 907 KQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGST-NVGRDL 1083
Q ++ R+ + + + +K L A + ++ + + + W+ EK + ST ++G DL
Sbjct: 932 TQEQLNQRWQQFRSLADGKKAALTSALSIQNYHLECTETQAWMREKTKVIESTQDLGNDL 991
Query: 1084 IGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLK 1263
GV L +K + ++ R+ E+ E + G+ I ++ +++ W DL+
Sbjct: 992 AGVLALQRKLAGTERDLEAISARVGELTQEANALAAGHPAQAPAINTRLGEVQTGWEDLR 1051
Query: 1264 NKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDALM 1443
+R + L ++ Q +L + ++W+ + V S E EALL +H AL
Sbjct: 1052 ATMRRREESLGEARRLQDFLRSLDDFQAWLGRTQTAVASEEGPATLPEAEALLAQHAALR 1111
Query: 1444 ADIEAYRSTIDSLRTQADACKMQEAPVSDSYGKETVMALYDYQEKNpreVSMRKG 1608
++E +S LRT + +A + ++ + AL E+ R R+G
Sbjct: 1112 GEVERAQSEYSRLRTLGEEVTRDQADPQCLFLRQRLEALGTGWEELGRMWESRQG 1166
Score = 145 bits (365), Expect = 5e-34
Identities = 135/647 (20%), Positives = 287/647 (44%), Gaps = 33/647 (5%)
Frame = +1
Query: 40 LQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLAAQEEKTQRLDD 219
LQ F R + +AW+ + + + + + +L EAL+ +H + + + RL
Sbjct: 1067 LQDFLRSLDDFQAWLGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRT 1126
Query: 220 IANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKL---RKGSLEDSHNYQLFDRDADEI 390
+ ++ + ++R + L EE ++ R+G L +H +Q F RDA +
Sbjct: 1127 LGEEVTRDQADPQCLFLRQRLEAL--GTGWEELGRMWESRQGRLAQAHGFQGFLRDARQA 1184
Query: 391 KAWIVEKLKTASDENYKEPTNLQSK---VQKHQNFLAEIAANEGRIDDVKSRGQSLLDSD 561
+ + + S + + P LQ+ ++K ++F++ + AN RI + G+ L+
Sbjct: 1185 EGVLSSQEYFLS--HTEMPGTLQAADAAIKKLEDFMSTMDANGERIRGLLEAGRQLVSKG 1242
Query: 562 HNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAEVESQLG 741
+ ++ IQ++ + ++K + A + L QQ F+++ +++++W+ E L
Sbjct: 1243 NIHAEKIQEKADSIEKRHRKNQEAVQQLLGRLRDNREQQHFLQDCQELKLWIDE--KMLT 1300
Query: 742 SDDCGKD-LNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAIKKKQIE 918
+ D D ++ +KH +++++++D +D ++ + + + +K +
Sbjct: 1301 AQDVSYDEARNLHTKWQKHQAFMAELAANKDWLDKVDKEGRELTLEKPELKVLVSEKLED 1360
Query: 919 VCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQN 1098
+ R+ +L+ + + L DA + F + E W+ + S + G+DL V
Sbjct: 1361 LHRRWDELETTTQAKARSLFDANRAELFAQSCSALESWLESLQAQLHSDDYGKDLTSVNI 1420
Query: 1099 LIKKHQAIQAEVTGHEPRILEVCNEGQKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADK 1278
L+KK Q ++ E+ E + + + + + + A ++E+ ++ + L
Sbjct: 1421 LLKKQQMLEREMAVREKEVEAIQAQAKALAQEDQSAG-EVERTSRAVEEKFRALCQPMKD 1479
Query: 1279 RRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKK---------- 1428
R + L S E Q+ D + W+ E+ P+ S E GKD S + L+KK
Sbjct: 1480 RCRRLQASREQHQFHRDVEDEILWVTERLPMASSLEHGKDLPSVQLLMKKNQTLQKEIQG 1539
Query: 1429 HDALMADIEAYRSTIDSLRTQADACKMQEAPVSDSY-----GK---ETVMALYDYQEKNP 1584
H+ +AD++ + T+ + + ++QE S+ GK E + A Y++
Sbjct: 1540 HEPRIADLKERQRTLGTAAAGPELAELQEMWKRLSHELELRGKRLEEALRAQQFYRDAAE 1599
Query: 1585 REVSMRKGDVLTLLNSNHKDWWKVEINDRQGHVP-------AAYVKKVDAMMSD-IDPNA 1740
E M + ++ + KD + ++ V A +K++ A D ID
Sbjct: 1600 AEAWMGEQELHMMGQEKAKDELSAQAEVKKHQVLEQALADYAQTIKQLAASSQDMIDHEH 1659
Query: 1741 PEQITVASQQKNLENQYENLLSLGKDRRDRLKDSVQAYQLVREANDL 1881
PE + +Q ++ Y L L +RR+RL++ ++ QL RE +DL
Sbjct: 1660 PESTRLTIRQAQVDKLYAGLKELAGERRERLQEHLRLCQLRRELDDL 1706
Score = 127 bits (318), Expect = 1e-28
Identities = 85/384 (22%), Positives = 184/384 (47%), Gaps = 2/384 (0%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
ERR ++++ L R+ + E WI ++E ++++G + V L K +F + +
Sbjct: 1685 ERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFSRDTS 1744
Query: 187 A-QEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQ 363
+E+ + +AN L+ GH A A V + +D L A+L E R L ++ Q
Sbjct: 1745 TIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAAYELQ 1804
Query: 364 LFDRDADEIKAWIVEKLKTASDENYKEPTNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQ 543
F A + A + K + D ++ ++ ++H + +I A ++ V+ G
Sbjct: 1805 RFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSTQVQQVQDDGL 1864
Query: 544 SLLDS-DHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLA 720
L + +K+++I + ++ + + W L +S + L + + +F + V ++ +W+
Sbjct: 1865 RLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELMLWMD 1924
Query: 721 EVESQLGSDDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAI 900
+ Q+ + + +D++S + K ++++I + DR + + + + NH+ A+ I
Sbjct: 1925 GINLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSACIDMGQELLARNHYAAEEI 1984
Query: 901 KKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRD 1080
+K ++ +R + E +++ + L ++ F RDA E W+ +EP+ S +G
Sbjct: 1985 SEKLSQLQSRRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAELGCT 2044
Query: 1081 LIGVQNLIKKHQAIQAEVTGHEPR 1152
+ V++LIK+H+A Q E R
Sbjct: 2045 VDEVESLIKRHEAFQKSAVAWEER 2068
Score = 118 bits (295), Expect = 7e-26
Identities = 112/495 (22%), Positives = 202/495 (40%), Gaps = 3/495 (0%)
Frame = +1
Query: 7 ERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKSLA 186
ER Q L F D EAW+ + + +VG S +AL R+H E+ +
Sbjct: 738 ERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPEVGHDEFSTQALARQHRALEEEIR 797
Query: 187 AQEEKTQRLDDIANKLVENGHYAAADVNKKRDDLLIRKANLEEKAKLRKGSLEDSHNYQL 366
A L + A L + +V + L L+ +A R +LE + +
Sbjct: 798 AHRPTLDALREQAAALPPALSH-TPEVQGRVPTLEQHYEELQARAGERARALEAALAFYT 856
Query: 367 FDRDADEIKAWIVEKLKTASDENYKEP-TNLQSKVQKHQNFLAEIAANEGRIDDVKSRGQ 543
+A W+ EK + + E +L+ Q+ + E+ A R+ V +
Sbjct: 857 MLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPEMNALAARVTAVSDIAE 916
Query: 544 SLLDSDHNKSDDIQQRIEELDKLWKDLVSASKIKETNLTQASGQQQFIRNVEDMEIWLAE 723
LL + D I E+L++ W+ S + K+ LT A Q + + + W+ E
Sbjct: 917 QLLKASPPGKDRIIGTQEQLNQRWQQFRSLADGKKAALTSALSIQNYHLECTETQAWMRE 976
Query: 724 VESQLGS-DDCGKDLNSVTNLQKKHNLLESDISSHQDRIDSFLQQADQFVHDNHFDADAI 900
+ S D G DL V LQ+K E D+ + R+ Q+A+ + A AI
Sbjct: 977 KTKVIESTQDLGNDLAGVLALQRKLAGTERDLEAISARVGELTQEANALAAGHPAQAPAI 1036
Query: 901 KKKQIEVCNRYSKLQEPLEKRKNKLNDAYKLHQFYRDADDEEDWIHEKEPIAGSTNVGRD 1080
+ EV + L+ + +R+ L +A +L F R DD + W+ + S
Sbjct: 1037 NTRLGEVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAWLGRTQTAVASEEGPAT 1096
Query: 1081 LIGVQNLIKKHQAIQAEVTGHEPRILEVCNEGQKMI-DGNHYANRDIEKKIDDMKNLWSD 1257
L + L+ +H A++ EV + + G+++ D + ++++ + W +
Sbjct: 1097 LPEAEALLAQHAALRGEVERAQSEYSRLRTLGEEVTRDQADPQCLFLRQRLEALGTGWEE 1156
Query: 1258 LKNKADKRRQLLDDSLEAQQYLADASEAESWMREKEPLVGSTEFGKDEDSTEALLKKHDA 1437
L + R+ L + Q +L DA +AE + +E + TE + +A +KK +
Sbjct: 1157 LGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYFLSHTEMPGTLQAADAAIKKLED 1216
Query: 1438 LMADIEAYRSTIDSL 1482
M+ ++A I L
Sbjct: 1217 FMSTMDANGERIRGL 1231
Score = 74.7 bits (182), Expect = 9e-13
Identities = 74/338 (21%), Positives = 137/338 (40%), Gaps = 43/338 (12%)
Frame = +1
Query: 997 QFYRDADDEEDWIHEKEPIAGSTNVGRDLIGVQNLIKKHQAIQAEVTGHEPRILEVCNEG 1176
+F R A E W+ E + + N G +L V+ ++KH+AI+ ++ + R+ V
Sbjct: 429 RFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGRVQAVDAVA 488
Query: 1177 QKMIDGNHYANRDIEKKIDDMKNLWSDLKNKADKRRQLLDDSLEAQQYLADASEAESWMR 1356
++ +++ + I + +++ LW L+ RR+ L +LE Q+ D WM
Sbjct: 489 AELAAEHYHDIKRIAARQNNVARLWDFLREMVAARRERLLLNLELQKVFQDLLYLMDWMA 548
Query: 1357 EKEPLVGSTEFGKDEDSTEALLKKHDALMADIEAYRSTIDSLRTQA----DACKMQEAPV 1524
E + + S + GK E LL+ H+ + ADI + ++ A D K + P
Sbjct: 549 EMKGRLQSQDLGKHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCDPGK-EYRPC 607
Query: 1525 SDSYGKETVMALYDYQEKNpreVSMRKG-------------------------------- 1608
E V L E + R+
Sbjct: 608 DPQLVSERVATLEQSYEALCELAATRRARLEESRRLWRFLWEVGEAEAWVREQQHLLASA 667
Query: 1609 -------DVLTLLNSNHKDWWKVEINDRQGHVPAAYVKKVDAMMSDIDPNAPEQITVASQ 1767
VL LLN + + E++ R G + +++ ++++ P A + T A++
Sbjct: 668 ETGRDLTGVLRLLNKHTA--LRGEMSGRLGPLKLT-LEQGQQLVAEGHPGANQASTRAAE 724
Query: 1768 QKNLENQYENLLSLGKDRRDRLKDSVQAYQLVREANDL 1881
L+ Q+E L +L ++R RL + YQ +AND+
Sbjct: 725 ---LQAQWERLEALAEERAQRLAQAASLYQFQADANDM 759
Score = 58.9 bits (141), Expect = 5e-08
Identities = 39/119 (32%), Positives = 65/119 (54%), Gaps = 3/119 (2%)
Frame = +1
Query: 1 WNERRFLYEQNMDLQLFYRDTEQAEAWIAKQEAFLENNDVGDSLDSVEALIRKHEDFEKS 180
W E+ + +++ +F RD AEAW+ QE + + ++G ++D VE+LI++HE F+KS
Sbjct: 2002 WQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAELGCTVDEVESLIKRHEAFQKS 2061
Query: 181 LAAQEEKTQRLDDI-ANKLVENGHYAAADVNKKRDDLLIRK--ANLEEKAKLRKGSLED 348
A EE+ L+ + A + EN + +KR++ RK E A +GSL D
Sbjct: 2062 AVAWEERFSALEKLTALEEREN------EQKRKREEEERRKQPPTSEPMASQPEGSLVD 2114
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.311 0.128 0.360
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 185,683,841
Number of Sequences: 369166
Number of extensions: 3627775
Number of successful extensions: 12385
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 10031
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 11466
length of database: 68,354,980
effective HSP length: 117
effective length of database: 46,740,985
effective search space used: 23837902350
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
Cluster detail
