Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00246 (826 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9VWA1|CLC_DROME Clathrin light chain (dClc) 79 2e-14 sp|O08585|CLCA_MOUSE Clathrin light chain A (Lca) 79 2e-14 sp|P08081|CLCA_RAT Clathrin light chain A (Lca) 75 2e-13 sp|P08082|CLCB_RAT Clathrin light chain B (Lcb) 75 2e-13 sp|Q6IRU5|CLCB_MOUSE Clathrin light chain B (Lcb) 75 2e-13 sp|P09497|CLCB_HUMAN Clathrin light chain B (Lcb) 75 3e-13 sp|P04973|CLCA_BOVIN Clathrin light chain A (Lca) 75 3e-13 sp|P04975|CLCB_BOVIN Clathrin light chain B (Lcb) 75 3e-13 sp|P09496|CLCA_HUMAN Clathrin light chain A (Lca) 73 8e-13 sp|Q9USP6|CLC1_SCHPO Clathrin light chain (CLC) 45 2e-04
>sp|Q9VWA1|CLC_DROME Clathrin light chain (dClc) Length = 219 Score = 79.0 bits (193), Expect = 2e-14 Identities = 52/131 (39%), Positives = 71/131 (54%), Gaps = 3/131 (2%) Frame = +3 Query: 279 RIEPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKL--- 449 R EPEKI WR E ++R+ +KD EE + L + +KKELDDW E ++K KL Sbjct: 100 REEPEKIRKWREEQKQRLEEKDIEEERKKEELRQQSKKELDDWLRQIGES-ISKTKLASR 158 Query: 450 NRETQGVFVKERDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDTSRMK 629 N E Q + E PG+EW+R+ K+C+FN + V G KD SRM+ Sbjct: 159 NAEKQAATL-ENGTIEPGTEWERIAKLCDFNPK-------VNKAG--------KDVSRMR 202 Query: 630 SILLSLKTDPL 662 SI L LK +P+ Sbjct: 203 SIYLHLKQNPI 213
>sp|O08585|CLCA_MOUSE Clathrin light chain A (Lca) Length = 235 Score = 78.6 bits (192), Expect = 2e-14 Identities = 55/184 (29%), Positives = 85/184 (46%), Gaps = 18/184 (9%) Frame = +3 Query: 168 PDSNDYASNDFTSNEFQENSSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDE 347 PD+ D N +QE++ P+ ++ + EV + EPE I WR E ER+ D Sbjct: 71 PDAVDGVMN---GEYYQESNG--PTDSYAAISEVDRLQSEPESIRKWREEQTERLEALDA 125 Query: 348 EELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRETQGVFVKER-------------- 485 ++ ++ A KEL++W + +EQL + NR + F K+ Sbjct: 126 NSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRAAEEAFYKQPFADVIGYVAAEEAF 185 Query: 486 ----DQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDTSRMKSILLSLKT 653 D+ PG+EW+RV +C+FN +S KD SRM+S+L+SLK Sbjct: 186 VNDIDESSPGTEWERVAPLCDFNPKSSKQA---------------KDVSRMRSVLISLKQ 230 Query: 654 DPLV 665 PLV Sbjct: 231 APLV 234
>sp|P08081|CLCA_RAT Clathrin light chain A (Lca) Length = 248 Score = 75.5 bits (184), Expect = 2e-13 Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 30/196 (15%) Frame = +3 Query: 168 PDSNDYASNDFTSNEFQENSSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDE 347 PD+ D N +QE++ P+ ++ + EV + EPE I WR E ER+ D Sbjct: 72 PDAVDGVMN---GEYYQESNG--PTDSYAAISEVDRLQSEPESIRKWREEQTERLEALDA 126 Query: 348 EELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNR------------------------ 455 ++ ++ A KEL++W + +EQL + NR Sbjct: 127 NSRKQEAEWKEKAVKELEEWYARQDEQLQKTKASNRVADEAFYKQPFADVIGYVTNINHP 186 Query: 456 ------ETQGVFVKERDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDT 617 + FV + D+ PG+EW+RV ++C+FN +S KD Sbjct: 187 CYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQA---------------KDV 231 Query: 618 SRMKSILLSLKTDPLV 665 SRM+S+L+SLK PLV Sbjct: 232 SRMRSVLISLKQAPLV 247
>sp|P08082|CLCB_RAT Clathrin light chain B (Lcb) Length = 229 Score = 75.1 bits (183), Expect = 2e-13 Identities = 45/147 (30%), Positives = 71/147 (48%), Gaps = 19/147 (12%) Frame = +3 Query: 285 EPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRE-- 458 EPE I WR E ++R+ + D + + AKK+L++WN +EQ + K K+N Sbjct: 99 EPESIRKWREEQKKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQ-VEKNKINNRIA 157 Query: 459 -----------------TQGVFVKERDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGE 587 ++ FVKE + PG+EW++V ++C+FN +S Sbjct: 158 DKAFYQQPDADTIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQC-------- 209 Query: 588 GIPVYTPKDTSRMKSILLSLKTDPLVR 668 KD SR++S+L+SLK PL R Sbjct: 210 -------KDVSRLRSVLMSLKQTPLSR 229
>sp|Q6IRU5|CLCB_MOUSE Clathrin light chain B (Lcb) Length = 229 Score = 75.1 bits (183), Expect = 2e-13 Identities = 45/147 (30%), Positives = 71/147 (48%), Gaps = 19/147 (12%) Frame = +3 Query: 285 EPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRE-- 458 EPE I WR E ++R+ + D + + AKK+L++WN +EQ + K K+N Sbjct: 99 EPESIRKWREEQKKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQ-VEKNKINNRIA 157 Query: 459 -----------------TQGVFVKERDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGE 587 ++ FVKE + PG+EW++V ++C+FN +S Sbjct: 158 DKAFYQQPDADTIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQC-------- 209 Query: 588 GIPVYTPKDTSRMKSILLSLKTDPLVR 668 KD SR++S+L+SLK PL R Sbjct: 210 -------KDVSRLRSVLMSLKQTPLSR 229
>sp|P09497|CLCB_HUMAN Clathrin light chain B (Lcb) Length = 229 Score = 74.7 bits (182), Expect = 3e-13 Identities = 45/147 (30%), Positives = 70/147 (47%), Gaps = 19/147 (12%) Frame = +3 Query: 285 EPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRE-- 458 EPE I WR E +R+ + D + + AKK+L++WN +EQ + K K+N Sbjct: 99 EPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQ-VEKNKINNRIA 157 Query: 459 -----------------TQGVFVKERDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGE 587 ++ FVKE + PG+EW++V ++C+FN +S Sbjct: 158 DKAFYQQPDADIIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQC-------- 209 Query: 588 GIPVYTPKDTSRMKSILLSLKTDPLVR 668 KD SR++S+L+SLK PL R Sbjct: 210 -------KDVSRLRSVLMSLKQTPLSR 229
>sp|P04973|CLCA_BOVIN Clathrin light chain A (Lca) Length = 243 Score = 74.7 bits (182), Expect = 3e-13 Identities = 54/196 (27%), Positives = 88/196 (44%), Gaps = 30/196 (15%) Frame = +3 Query: 168 PDSNDYASNDFTSNEFQENSSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDE 347 PD+ D +N + +QE++ P+ ++ + +V + EPE I WR E ER+ D Sbjct: 67 PDAVDGVTN---GDYYQESNG--PTDSYAAISQVDRLQSEPESIRKWREEQTERLEALDA 121 Query: 348 EELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNR------------------------ 455 ++ ++ A KELD+W + +EQL + NR Sbjct: 122 NSRKQEAEWKEKAIKELDEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYVTNINHP 181 Query: 456 ------ETQGVFVKERDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDT 617 + FV + ++ PG+EW+RV ++C+FN +S KD Sbjct: 182 CYSLEQAAEEAFVNDIEESSPGTEWERVARLCDFNPKSSKQA---------------KDV 226 Query: 618 SRMKSILLSLKTDPLV 665 SRM+S+L+SLK PLV Sbjct: 227 SRMRSVLISLKQAPLV 242
>sp|P04975|CLCB_BOVIN Clathrin light chain B (Lcb) Length = 228 Score = 74.7 bits (182), Expect = 3e-13 Identities = 45/147 (30%), Positives = 70/147 (47%), Gaps = 19/147 (12%) Frame = +3 Query: 285 EPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRE-- 458 EPE I WR E +R+ + D + + AKK+L++WN +EQ + K K+N Sbjct: 98 EPESIRKWREEQRKRLQELDAASKVMEQEWREKAKKDLEEWNQRQSEQ-VEKNKINNRIA 156 Query: 459 -----------------TQGVFVKERDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGE 587 ++ FVKE + PG+EW++V ++C+FN +S Sbjct: 157 DKAFYQQPDADIIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQC-------- 208 Query: 588 GIPVYTPKDTSRMKSILLSLKTDPLVR 668 KD SR++S+L+SLK PL R Sbjct: 209 -------KDVSRLRSVLMSLKQTPLSR 228
>sp|P09496|CLCA_HUMAN Clathrin light chain A (Lca) Length = 248 Score = 73.2 bits (178), Expect = 8e-13 Identities = 54/196 (27%), Positives = 86/196 (43%), Gaps = 30/196 (15%) Frame = +3 Query: 168 PDSNDYASNDFTSNEFQENSSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDE 347 PD+ D N +QE++ P+ ++ + +V + EPE I WR E ER+ D Sbjct: 72 PDAVDGVMN---GEYYQESNG--PTDSYAAISQVDRLQSEPESIRKWREEQMERLEALDA 126 Query: 348 EELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNR------------------------ 455 ++ ++ A KEL++W + +EQL + NR Sbjct: 127 NSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYVTNINHP 186 Query: 456 ------ETQGVFVKERDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDT 617 + FV + D+ PG+EW+RV ++C+FN +S KD Sbjct: 187 CYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQA---------------KDV 231 Query: 618 SRMKSILLSLKTDPLV 665 SRM+S+L+SLK PLV Sbjct: 232 SRMRSVLISLKQAPLV 247
>sp|Q9USP6|CLC1_SCHPO Clathrin light chain (CLC) Length = 229 Score = 45.1 bits (105), Expect = 2e-04 Identities = 40/180 (22%), Positives = 77/180 (42%), Gaps = 11/180 (6%) Frame = +3 Query: 150 DGFETFPDSNDYASNDFTSN------EFQENSSY-LPSTNFDSRPEVSIPRIE---PEKI 299 D F + ++ F N E Q + ++ P + + EV P E PE + Sbjct: 50 DALLNFENDSEAEQTRFEQNFPPIDAEMQASGTFSAPKAPYMGQAEVHPPEDESGDPEPV 109 Query: 300 LVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRETQGVFVK 479 W+ + +RI ++DE + + A+K +DD+ + N++ +R+ Q ++ Sbjct: 110 RKWKEDQMKRIQERDESSKKLRESNIEKARKAIDDFYENFNDKRDKVIAKSRKEQEKLLE 169 Query: 480 ERDQPIPG-SEWQRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDTSRMKSILLSLKTD 656 E + G + W+R+ K+ + + KP A G + T R + +L+SL D Sbjct: 170 ENESKSTGTTSWERILKLIDLSD------KPEAHG---------RSTERFRELLISLAKD 214
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 80,147,143 Number of Sequences: 369166 Number of extensions: 1553375 Number of successful extensions: 5682 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5172 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5627 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 7956112725 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)