Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_P15
(561 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9VWA1|CLC_DROME Clathrin light chain (dClc) 79 6e-15
sp|O08585|CLCA_MOUSE Clathrin light chain A (Lca) 78 1e-14
sp|P08082|CLCB_RAT Clathrin light chain B (Lcb) 77 2e-14
sp|Q6IRU5|CLCB_MOUSE Clathrin light chain B (Lcb) 77 2e-14
sp|P09497|CLCB_HUMAN Clathrin light chain B (Lcb) 77 3e-14
sp|P04975|CLCB_BOVIN Clathrin light chain B (Lcb) 77 3e-14
sp|P08081|CLCA_RAT Clathrin light chain A (Lca) 75 1e-13
sp|P04973|CLCA_BOVIN Clathrin light chain A (Lca) 73 4e-13
sp|P09496|CLCA_HUMAN Clathrin light chain A (Lca) 73 5e-13
sp|Q9USP6|CLC1_SCHPO Clathrin light chain (CLC) 45 9e-05
>sp|Q9VWA1|CLC_DROME Clathrin light chain (dClc)
Length = 219
Score = 79.3 bits (194), Expect = 6e-15
Identities = 52/131 (39%), Positives = 71/131 (54%), Gaps = 3/131 (2%)
Frame = +1
Query: 70 RIEPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKL--- 240
R EPEKI WR E ++R+ +KD EE + L + +KKELDDW E ++K KL
Sbjct: 100 REEPEKIRKWREEQKQRLEEKDIEEERKKEELRQQSKKELDDWLRQIGES-ISKTKLASR 158
Query: 241 NRETQGVFVKERDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDTSRMR 420
N E Q + E PG+EW+R+ K+C+FN + V G KD SRMR
Sbjct: 159 NAEKQAATL-ENGTIEPGTEWERIAKLCDFNPK-------VNKAG--------KDVSRMR 202
Query: 421 SILMSLKTDPL 453
SI + LK +P+
Sbjct: 203 SIYLHLKQNPI 213
>sp|O08585|CLCA_MOUSE Clathrin light chain A (Lca)
Length = 235
Score = 78.2 bits (191), Expect = 1e-14
Identities = 52/169 (30%), Positives = 80/169 (47%), Gaps = 18/169 (10%)
Frame = +1
Query: 4 FQENSSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDEEELERMRILEKDAKK 183
+QE++ P+ ++ + EV + EPE I WR E ER+ D ++ ++ A K
Sbjct: 83 YQESNG--PTDSYAAISEVDRLQSEPESIRKWREEQTERLEALDANSRKQEAEWKEKAIK 140
Query: 184 ELDDWNSHHNEQLLNKRKLNRETQGVFVKER------------------DQPIPGSEWQR 309
EL++W + +EQL + NR + F K+ D+ PG+EW+R
Sbjct: 141 ELEEWYARQDEQLQKTKANNRAAEEAFYKQPFADVIGYVAAEEAFVNDIDESSPGTEWER 200
Query: 310 VCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDTSRMRSILMSLKTDPLV 456
V +C+FN +S KD SRMRS+L+SLK PLV
Sbjct: 201 VAPLCDFNPKSSKQA---------------KDVSRMRSVLISLKQAPLV 234
>sp|P08082|CLCB_RAT Clathrin light chain B (Lcb)
Length = 229
Score = 77.4 bits (189), Expect = 2e-14
Identities = 47/147 (31%), Positives = 71/147 (48%), Gaps = 19/147 (12%)
Frame = +1
Query: 76 EPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRE-- 249
EPE I WR E ++R+ + D + + AKK+L++WN +EQ + K K+N
Sbjct: 99 EPESIRKWREEQKKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQ-VEKNKINNRIA 157
Query: 250 -----------------TQGVFVKERDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGE 378
++ FVKE + PG+EW++V ++C+FN +S
Sbjct: 158 DKAFYQQPDADTIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQC-------- 209
Query: 379 GIPVYTPKDTSRMRSILMSLKTDPLVR 459
KD SR+RS+LMSLK PL R
Sbjct: 210 -------KDVSRLRSVLMSLKQTPLSR 229
>sp|Q6IRU5|CLCB_MOUSE Clathrin light chain B (Lcb)
Length = 229
Score = 77.4 bits (189), Expect = 2e-14
Identities = 47/147 (31%), Positives = 71/147 (48%), Gaps = 19/147 (12%)
Frame = +1
Query: 76 EPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRE-- 249
EPE I WR E ++R+ + D + + AKK+L++WN +EQ + K K+N
Sbjct: 99 EPESIRKWREEQKKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQ-VEKNKINNRIA 157
Query: 250 -----------------TQGVFVKERDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGE 378
++ FVKE + PG+EW++V ++C+FN +S
Sbjct: 158 DKAFYQQPDADTIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQC-------- 209
Query: 379 GIPVYTPKDTSRMRSILMSLKTDPLVR 459
KD SR+RS+LMSLK PL R
Sbjct: 210 -------KDVSRLRSVLMSLKQTPLSR 229
>sp|P09497|CLCB_HUMAN Clathrin light chain B (Lcb)
Length = 229
Score = 77.0 bits (188), Expect = 3e-14
Identities = 47/147 (31%), Positives = 70/147 (47%), Gaps = 19/147 (12%)
Frame = +1
Query: 76 EPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRE-- 249
EPE I WR E +R+ + D + + AKK+L++WN +EQ + K K+N
Sbjct: 99 EPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQ-VEKNKINNRIA 157
Query: 250 -----------------TQGVFVKERDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGE 378
++ FVKE + PG+EW++V ++C+FN +S
Sbjct: 158 DKAFYQQPDADIIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQC-------- 209
Query: 379 GIPVYTPKDTSRMRSILMSLKTDPLVR 459
KD SR+RS+LMSLK PL R
Sbjct: 210 -------KDVSRLRSVLMSLKQTPLSR 229
>sp|P04975|CLCB_BOVIN Clathrin light chain B (Lcb)
Length = 228
Score = 77.0 bits (188), Expect = 3e-14
Identities = 47/147 (31%), Positives = 70/147 (47%), Gaps = 19/147 (12%)
Frame = +1
Query: 76 EPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRE-- 249
EPE I WR E +R+ + D + + AKK+L++WN +EQ + K K+N
Sbjct: 98 EPESIRKWREEQRKRLQELDAASKVMEQEWREKAKKDLEEWNQRQSEQ-VEKNKINNRIA 156
Query: 250 -----------------TQGVFVKERDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGE 378
++ FVKE + PG+EW++V ++C+FN +S
Sbjct: 157 DKAFYQQPDADIIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQC-------- 208
Query: 379 GIPVYTPKDTSRMRSILMSLKTDPLVR 459
KD SR+RS+LMSLK PL R
Sbjct: 209 -------KDVSRLRSVLMSLKQTPLSR 228
>sp|P08081|CLCA_RAT Clathrin light chain A (Lca)
Length = 248
Score = 75.1 bits (183), Expect = 1e-13
Identities = 52/181 (28%), Positives = 81/181 (44%), Gaps = 30/181 (16%)
Frame = +1
Query: 4 FQENSSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDEEELERMRILEKDAKK 183
+QE++ P+ ++ + EV + EPE I WR E ER+ D ++ ++ A K
Sbjct: 84 YQESNG--PTDSYAAISEVDRLQSEPESIRKWREEQTERLEALDANSRKQEAEWKEKAVK 141
Query: 184 ELDDWNSHHNEQLLNKRKLNR------------------------------ETQGVFVKE 273
EL++W + +EQL + NR + FV +
Sbjct: 142 ELEEWYARQDEQLQKTKASNRVADEAFYKQPFADVIGYVTNINHPCYSLEQAAEEAFVND 201
Query: 274 RDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDTSRMRSILMSLKTDPL 453
D+ PG+EW+RV ++C+FN +S KD SRMRS+L+SLK PL
Sbjct: 202 IDESSPGTEWERVARLCDFNPKSSKQA---------------KDVSRMRSVLISLKQAPL 246
Query: 454 V 456
V
Sbjct: 247 V 247
>sp|P04973|CLCA_BOVIN Clathrin light chain A (Lca)
Length = 243
Score = 73.2 bits (178), Expect = 4e-13
Identities = 51/181 (28%), Positives = 81/181 (44%), Gaps = 30/181 (16%)
Frame = +1
Query: 4 FQENSSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDEEELERMRILEKDAKK 183
+QE++ P+ ++ + +V + EPE I WR E ER+ D ++ ++ A K
Sbjct: 79 YQESNG--PTDSYAAISQVDRLQSEPESIRKWREEQTERLEALDANSRKQEAEWKEKAIK 136
Query: 184 ELDDWNSHHNEQLLNKRKLNR------------------------------ETQGVFVKE 273
ELD+W + +EQL + NR + FV +
Sbjct: 137 ELDEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYVTNINHPCYSLEQAAEEAFVND 196
Query: 274 RDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDTSRMRSILMSLKTDPL 453
++ PG+EW+RV ++C+FN +S KD SRMRS+L+SLK PL
Sbjct: 197 IEESSPGTEWERVARLCDFNPKSSKQA---------------KDVSRMRSVLISLKQAPL 241
Query: 454 V 456
V
Sbjct: 242 V 242
>sp|P09496|CLCA_HUMAN Clathrin light chain A (Lca)
Length = 248
Score = 72.8 bits (177), Expect = 5e-13
Identities = 51/181 (28%), Positives = 81/181 (44%), Gaps = 30/181 (16%)
Frame = +1
Query: 4 FQENSSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDEEELERMRILEKDAKK 183
+QE++ P+ ++ + +V + EPE I WR E ER+ D ++ ++ A K
Sbjct: 84 YQESNG--PTDSYAAISQVDRLQSEPESIRKWREEQMERLEALDANSRKQEAEWKEKAIK 141
Query: 184 ELDDWNSHHNEQLLNKRKLNR------------------------------ETQGVFVKE 273
EL++W + +EQL + NR + FV +
Sbjct: 142 ELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYVTNINHPCYSLEQAAEEAFVND 201
Query: 274 RDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDTSRMRSILMSLKTDPL 453
D+ PG+EW+RV ++C+FN +S KD SRMRS+L+SLK PL
Sbjct: 202 IDESSPGTEWERVARLCDFNPKSSKQA---------------KDVSRMRSVLISLKQAPL 246
Query: 454 V 456
V
Sbjct: 247 V 247
>sp|Q9USP6|CLC1_SCHPO Clathrin light chain (CLC)
Length = 229
Score = 45.4 bits (106), Expect = 9e-05
Identities = 37/154 (24%), Positives = 70/154 (45%), Gaps = 5/154 (3%)
Frame = +1
Query: 1 EFQENSSY-LPSTNFDSRPEVSIPRIE---PEKILVWRREFEERILKKDEEELERMRILE 168
E Q + ++ P + + EV P E PE + W+ + +RI ++DE +
Sbjct: 76 EMQASGTFSAPKAPYMGQAEVHPPEDESGDPEPVRKWKEDQMKRIQERDESSKKLRESNI 135
Query: 169 KDAKKELDDWNSHHNEQLLNKRKLNRETQGVFVKERDQPIPG-SEWQRVCKMCEFNTRSG 345
+ A+K +DD+ + N++ +R+ Q ++E + G + W+R+ K+ + +
Sbjct: 136 EKARKAIDDFYENFNDKRDKVIAKSRKEQEKLLEENESKSTGTTSWERILKLIDLSD--- 192
Query: 346 VTVKPVAPGGEGIPVYTPKDTSRMRSILMSLKTD 447
KP A G + T R R +L+SL D
Sbjct: 193 ---KPEAHG---------RSTERFRELLISLAKD 214
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,308,787
Number of Sequences: 369166
Number of extensions: 1210263
Number of successful extensions: 4956
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4486
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4901
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4029688280
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)