Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_O17
(638 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9VWA1|CLC_DROME Clathrin light chain (dClc) 64 4e-10
sp|O08585|CLCA_MOUSE Clathrin light chain A (Lca) 57 3e-08
sp|P08082|CLCB_RAT Clathrin light chain B (Lcb) 55 1e-07
sp|Q6IRU5|CLCB_MOUSE Clathrin light chain B (Lcb) 55 1e-07
sp|P09497|CLCB_HUMAN Clathrin light chain B (Lcb) 55 2e-07
sp|P04975|CLCB_BOVIN Clathrin light chain B (Lcb) 55 2e-07
sp|P08081|CLCA_RAT Clathrin light chain A (Lca) 54 3e-07
sp|P04973|CLCA_BOVIN Clathrin light chain A (Lca) 54 4e-07
sp|P09496|CLCA_HUMAN Clathrin light chain A (Lca) 52 1e-06
sp|Q9USP6|CLC1_SCHPO Clathrin light chain (CLC) 39 0.011
>sp|Q9VWA1|CLC_DROME Clathrin light chain (dClc)
Length = 219
Score = 63.5 bits (153), Expect = 4e-10
Identities = 37/88 (42%), Positives = 51/88 (57%), Gaps = 3/88 (3%)
Frame = +2
Query: 152 RIEPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKL--- 322
R EPEKI WR E ++R+ +KD EE + L + +KKELDDW E ++K KL
Sbjct: 100 REEPEKIRKWREEQKQRLEEKDIEEERKKEELRQQSKKELDDWLRQIGES-ISKTKLASR 158
Query: 323 NRETQGVFVKERDQPIPGSEWQRVCKMC 406
N E Q + E PG+EW+R+ K+C
Sbjct: 159 NAEKQAATL-ENGTIEPGTEWERIAKLC 185
>sp|O08585|CLCA_MOUSE Clathrin light chain A (Lca)
Length = 235
Score = 57.4 bits (137), Expect = 3e-08
Identities = 39/140 (27%), Positives = 64/140 (45%), Gaps = 18/140 (12%)
Frame = +2
Query: 41 PDSNDYASNDFTSNEFQENSSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDE 220
PD+ D N +QE++ P+ ++ + EV + EPE I WR E ER+ D
Sbjct: 71 PDAVDGVMN---GEYYQESNG--PTDSYAAISEVDRLQSEPESIRKWREEQTERLEALDA 125
Query: 221 EELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRETQGVFVKER-------------- 358
++ ++ A KEL++W + +EQL + NR + F K+
Sbjct: 126 NSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRAAEEAFYKQPFADVIGYVAAEEAF 185
Query: 359 ----DQPIPGSEWQRVCKMC 406
D+ PG+EW+RV +C
Sbjct: 186 VNDIDESSPGTEWERVAPLC 205
Score = 29.6 bits (65), Expect = 6.8
Identities = 13/19 (68%), Positives = 16/19 (84%)
Frame = +3
Query: 483 KDTSRMKSILLSLKTDPLV 539
KD SRM+S+L+SLK PLV
Sbjct: 216 KDVSRMRSVLISLKQAPLV 234
>sp|P08082|CLCB_RAT Clathrin light chain B (Lcb)
Length = 229
Score = 55.5 bits (132), Expect = 1e-07
Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 19/102 (18%)
Frame = +2
Query: 158 EPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRE-- 331
EPE I WR E ++R+ + D + + AKK+L++WN +EQ + K K+N
Sbjct: 99 EPESIRKWREEQKKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQ-VEKNKINNRIA 157
Query: 332 -----------------TQGVFVKERDQPIPGSEWQRVCKMC 406
++ FVKE + PG+EW++V ++C
Sbjct: 158 DKAFYQQPDADTIGYVASEEAFVKESKEETPGTEWEKVAQLC 199
>sp|Q6IRU5|CLCB_MOUSE Clathrin light chain B (Lcb)
Length = 229
Score = 55.5 bits (132), Expect = 1e-07
Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 19/102 (18%)
Frame = +2
Query: 158 EPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRE-- 331
EPE I WR E ++R+ + D + + AKK+L++WN +EQ + K K+N
Sbjct: 99 EPESIRKWREEQKKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQ-VEKNKINNRIA 157
Query: 332 -----------------TQGVFVKERDQPIPGSEWQRVCKMC 406
++ FVKE + PG+EW++V ++C
Sbjct: 158 DKAFYQQPDADTIGYVASEEAFVKESKEETPGTEWEKVAQLC 199
>sp|P09497|CLCB_HUMAN Clathrin light chain B (Lcb)
Length = 229
Score = 55.1 bits (131), Expect = 2e-07
Identities = 30/102 (29%), Positives = 49/102 (48%), Gaps = 19/102 (18%)
Frame = +2
Query: 158 EPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRE-- 331
EPE I WR E +R+ + D + + AKK+L++WN +EQ + K K+N
Sbjct: 99 EPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQ-VEKNKINNRIA 157
Query: 332 -----------------TQGVFVKERDQPIPGSEWQRVCKMC 406
++ FVKE + PG+EW++V ++C
Sbjct: 158 DKAFYQQPDADIIGYVASEEAFVKESKEETPGTEWEKVAQLC 199
>sp|P04975|CLCB_BOVIN Clathrin light chain B (Lcb)
Length = 228
Score = 55.1 bits (131), Expect = 2e-07
Identities = 30/102 (29%), Positives = 49/102 (48%), Gaps = 19/102 (18%)
Frame = +2
Query: 158 EPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRE-- 331
EPE I WR E +R+ + D + + AKK+L++WN +EQ + K K+N
Sbjct: 98 EPESIRKWREEQRKRLQELDAASKVMEQEWREKAKKDLEEWNQRQSEQ-VEKNKINNRIA 156
Query: 332 -----------------TQGVFVKERDQPIPGSEWQRVCKMC 406
++ FVKE + PG+EW++V ++C
Sbjct: 157 DKAFYQQPDADIIGYVASEEAFVKESKEETPGTEWEKVAQLC 198
>sp|P08081|CLCA_RAT Clathrin light chain A (Lca)
Length = 248
Score = 54.3 bits (129), Expect = 3e-07
Identities = 39/152 (25%), Positives = 65/152 (42%), Gaps = 30/152 (19%)
Frame = +2
Query: 41 PDSNDYASNDFTSNEFQENSSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDE 220
PD+ D N +QE++ P+ ++ + EV + EPE I WR E ER+ D
Sbjct: 72 PDAVDGVMN---GEYYQESNG--PTDSYAAISEVDRLQSEPESIRKWREEQTERLEALDA 126
Query: 221 EELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNR------------------------ 328
++ ++ A KEL++W + +EQL + NR
Sbjct: 127 NSRKQEAEWKEKAVKELEEWYARQDEQLQKTKASNRVADEAFYKQPFADVIGYVTNINHP 186
Query: 329 ------ETQGVFVKERDQPIPGSEWQRVCKMC 406
+ FV + D+ PG+EW+RV ++C
Sbjct: 187 CYSLEQAAEEAFVNDIDESSPGTEWERVARLC 218
Score = 29.6 bits (65), Expect = 6.8
Identities = 13/19 (68%), Positives = 16/19 (84%)
Frame = +3
Query: 483 KDTSRMKSILLSLKTDPLV 539
KD SRM+S+L+SLK PLV
Sbjct: 229 KDVSRMRSVLISLKQAPLV 247
>sp|P04973|CLCA_BOVIN Clathrin light chain A (Lca)
Length = 243
Score = 53.5 bits (127), Expect = 4e-07
Identities = 38/152 (25%), Positives = 67/152 (44%), Gaps = 30/152 (19%)
Frame = +2
Query: 41 PDSNDYASNDFTSNEFQENSSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDE 220
PD+ D +N + +QE++ P+ ++ + +V + EPE I WR E ER+ D
Sbjct: 67 PDAVDGVTN---GDYYQESNG--PTDSYAAISQVDRLQSEPESIRKWREEQTERLEALDA 121
Query: 221 EELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNR------------------------ 328
++ ++ A KELD+W + +EQL + NR
Sbjct: 122 NSRKQEAEWKEKAIKELDEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYVTNINHP 181
Query: 329 ------ETQGVFVKERDQPIPGSEWQRVCKMC 406
+ FV + ++ PG+EW+RV ++C
Sbjct: 182 CYSLEQAAEEAFVNDIEESSPGTEWERVARLC 213
Score = 29.6 bits (65), Expect = 6.8
Identities = 13/19 (68%), Positives = 16/19 (84%)
Frame = +3
Query: 483 KDTSRMKSILLSLKTDPLV 539
KD SRM+S+L+SLK PLV
Sbjct: 224 KDVSRMRSVLISLKQAPLV 242
>sp|P09496|CLCA_HUMAN Clathrin light chain A (Lca)
Length = 248
Score = 52.0 bits (123), Expect = 1e-06
Identities = 38/152 (25%), Positives = 65/152 (42%), Gaps = 30/152 (19%)
Frame = +2
Query: 41 PDSNDYASNDFTSNEFQENSSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDE 220
PD+ D N +QE++ P+ ++ + +V + EPE I WR E ER+ D
Sbjct: 72 PDAVDGVMN---GEYYQESNG--PTDSYAAISQVDRLQSEPESIRKWREEQMERLEALDA 126
Query: 221 EELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNR------------------------ 328
++ ++ A KEL++W + +EQL + NR
Sbjct: 127 NSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYVTNINHP 186
Query: 329 ------ETQGVFVKERDQPIPGSEWQRVCKMC 406
+ FV + D+ PG+EW+RV ++C
Sbjct: 187 CYSLEQAAEEAFVNDIDESSPGTEWERVARLC 218
Score = 29.6 bits (65), Expect = 6.8
Identities = 13/19 (68%), Positives = 16/19 (84%)
Frame = +3
Query: 483 KDTSRMKSILLSLKTDPLV 539
KD SRM+S+L+SLK PLV
Sbjct: 229 KDVSRMRSVLISLKQAPLV 247
>sp|Q9USP6|CLC1_SCHPO Clathrin light chain (CLC)
Length = 229
Score = 38.9 bits (89), Expect = 0.011
Identities = 30/138 (21%), Positives = 61/138 (44%), Gaps = 11/138 (7%)
Frame = +2
Query: 23 DGFETFPDSNDYASNDFTSN------EFQENSSY-LPSTNFDSRPEVSIPRIE---PEKI 172
D F + ++ F N E Q + ++ P + + EV P E PE +
Sbjct: 50 DALLNFENDSEAEQTRFEQNFPPIDAEMQASGTFSAPKAPYMGQAEVHPPEDESGDPEPV 109
Query: 173 LVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRETQGVFVK 352
W+ + +RI ++DE + + A+K +DD+ + N++ +R+ Q ++
Sbjct: 110 RKWKEDQMKRIQERDESSKKLRESNIEKARKAIDDFYENFNDKRDKVIAKSRKEQEKLLE 169
Query: 353 ERDQPIPG-SEWQRVCKM 403
E + G + W+R+ K+
Sbjct: 170 ENESKSTGTTSWERILKL 187
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,099,950
Number of Sequences: 369166
Number of extensions: 1289610
Number of successful extensions: 5161
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4697
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5114
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5169945420
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)