Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_C04
(784 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9VWA1|CLC_DROME Clathrin light chain (dClc) 82 2e-15
sp|O08585|CLCA_MOUSE Clathrin light chain A (Lca) 81 3e-15
sp|Q6IRU5|CLCB_MOUSE Clathrin light chain B (Lcb) 81 4e-15
sp|P04973|CLCA_BOVIN Clathrin light chain A (Lca) 80 5e-15
sp|P08082|CLCB_RAT Clathrin light chain B (Lcb) 80 5e-15
sp|P08081|CLCA_RAT Clathrin light chain A (Lca) 80 6e-15
sp|P04975|CLCB_BOVIN Clathrin light chain B (Lcb) 79 1e-14
sp|P09497|CLCB_HUMAN Clathrin light chain B (Lcb) 78 2e-14
sp|P09496|CLCA_HUMAN Clathrin light chain A (Lca) 77 5e-14
sp|Q9USP6|CLC1_SCHPO Clathrin light chain (CLC) 51 4e-06
>sp|Q9VWA1|CLC_DROME Clathrin light chain (dClc)
Length = 219
Score = 82.0 bits (201), Expect = 2e-15
Identities = 72/217 (33%), Positives = 100/217 (46%), Gaps = 12/217 (5%)
Frame = +3
Query: 24 DLIADFLAREQEQLGDID-DFKFDEINHDSFNSQVDGFETF----PDSNDYASNDFTSNE 188
D A+FLAREQ LGD++ + + S +G D S T
Sbjct: 14 DPAAEFLAREQSALGDLEAEITGGSASAPPAASTDEGLGELLGGTASEGDLLSAGGTGGL 73
Query: 189 FQENSSYLPSTNFDSRPE-VSIP---RIEPEKILVWRREFEERILKKDEEELERMRILEK 356
S+ + P +S P R EPEKI WR E ++R+ +KD EE + L +
Sbjct: 74 ESSTGSFEVIGGESNEPVGISGPPPSREEPEKIRKWREEQKQRLEEKDIEEERKKEELRQ 133
Query: 357 DAKKELDDWNSHHNEQLLNKRKL---NRETQGVFVKERDQPIPGSEWQRVCKMCEFNTRS 527
+KKELDDW E ++K KL N E Q + E PG+EW+R+ K+C+FN +
Sbjct: 134 QSKKELDDWLRQIGES-ISKTKLASRNAEKQAATL-ENGTIEPGTEWERIAKLCDFNPK- 190
Query: 528 GVTVKPVAPGGEGIPVYTPKDTSRMKSILLSLKTDPL 638
V G KD SRM+SI L LK +P+
Sbjct: 191 ------VNKAG--------KDVSRMRSIYLHLKQNPI 213
>sp|O08585|CLCA_MOUSE Clathrin light chain A (Lca)
Length = 235
Score = 81.3 bits (199), Expect = 3e-15
Identities = 64/225 (28%), Positives = 101/225 (44%), Gaps = 19/225 (8%)
Frame = +3
Query: 24 DLIADFLAREQEQLGDID-DFKFDEINHDSFNSQVDGFETFPDSNDYASNDFTSNEFQEN 200
D A FLA E+ ++ I+ D F ++ + PD+ D N +QE+
Sbjct: 30 DPAAAFLAHEESEIAGIENDEAFAILDGGAPGRATRRAGGGPDAVDGVMN---GEYYQES 86
Query: 201 SSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDD 380
+ P+ ++ + EV + EPE I WR E ER+ D ++ ++ A KEL++
Sbjct: 87 NG--PTDSYAAISEVDRLQSEPESIRKWREEQTERLEALDANSRKQEAEWKEKAIKELEE 144
Query: 381 WNSHHNEQLLNKRKLNRETQGVFVKER------------------DQPIPGSEWQRVCKM 506
W + +EQL + NR + F K+ D+ PG+EW+RV +
Sbjct: 145 WYARQDEQLQKTKANNRAAEEAFYKQPFADVIGYVAAEEAFVNDIDESSPGTEWERVAPL 204
Query: 507 CEFNTRSGVTVKPVAPGGEGIPVYTPKDTSRMKSILLSLKTDPLV 641
C+FN +S KD SRM+S+L+SLK PLV
Sbjct: 205 CDFNPKSSKQA---------------KDVSRMRSVLISLKQAPLV 234
>sp|Q6IRU5|CLCB_MOUSE Clathrin light chain B (Lcb)
Length = 229
Score = 80.9 bits (198), Expect = 4e-15
Identities = 63/232 (27%), Positives = 103/232 (44%), Gaps = 20/232 (8%)
Frame = +3
Query: 9 QAIMSDLIADFLAREQEQLGDID-DFKFDEINHDSFNSQVDGFETFPDSNDYASNDFTSN 185
+A D A FLA+++ ++ I+ D F S G + S D S +
Sbjct: 17 EAAEEDPAAAFLAQQESEIAGIENDPGFGAPAASQVASAQPGLASGAGSEDM-STTVNGD 75
Query: 186 EFQENSSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDEEELERMRILEKDAK 365
FQE + P+ + + + EPE I WR E ++R+ + D + + AK
Sbjct: 76 VFQEANG--PADGYAAIAQADRLTQEPESIRKWREEQKKRLQELDAASKVTEQEWREKAK 133
Query: 366 KELDDWNSHHNEQLLNKRKLNRE-------------------TQGVFVKERDQPIPGSEW 488
K+L++WN +EQ + K K+N ++ FVKE + PG+EW
Sbjct: 134 KDLEEWNQRQSEQ-VEKNKINNRIADKAFYQQPDADTIGYVASEEAFVKESKEETPGTEW 192
Query: 489 QRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDTSRMKSILLSLKTDPLVR 644
++V ++C+FN +S KD SR++S+L+SLK PL R
Sbjct: 193 EKVAQLCDFNPKSSKQC---------------KDVSRLRSVLMSLKQTPLSR 229
>sp|P04973|CLCA_BOVIN Clathrin light chain A (Lca)
Length = 243
Score = 80.5 bits (197), Expect = 5e-15
Identities = 65/238 (27%), Positives = 108/238 (45%), Gaps = 32/238 (13%)
Frame = +3
Query: 24 DLIADFLAREQEQLGDID-DFKFDEINHDSFNSQVDGFET-FPDSNDYASNDFTSNEFQE 197
D A FLA+++ ++ I+ D F ++ + SQ G PD+ D +N + +QE
Sbjct: 25 DPAAAFLAQQESEIAGIENDEAFAILDGGAPGSQPHGEPPGIPDAVDGVTN---GDYYQE 81
Query: 198 NSSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDEEELERMRILEKDAKKELD 377
++ P+ ++ + +V + EPE I WR E ER+ D ++ ++ A KELD
Sbjct: 82 SNG--PTDSYAAISQVDRLQSEPESIRKWREEQTERLEALDANSRKQEAEWKEKAIKELD 139
Query: 378 DWNSHHNEQLLNKRKLNR------------------------------ETQGVFVKERDQ 467
+W + +EQL + NR + FV + ++
Sbjct: 140 EWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYVTNINHPCYSLEQAAEEAFVNDIEE 199
Query: 468 PIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDTSRMKSILLSLKTDPLV 641
PG+EW+RV ++C+FN +S KD SRM+S+L+SLK PLV
Sbjct: 200 SSPGTEWERVARLCDFNPKSSKQA---------------KDVSRMRSVLISLKQAPLV 242
>sp|P08082|CLCB_RAT Clathrin light chain B (Lcb)
Length = 229
Score = 80.5 bits (197), Expect = 5e-15
Identities = 62/232 (26%), Positives = 103/232 (44%), Gaps = 20/232 (8%)
Frame = +3
Query: 9 QAIMSDLIADFLAREQEQLGDID-DFKFDEINHDSFNSQVDGFETFPDSNDYASNDFTSN 185
+A D A FLA+++ ++ I+ D F S G + S D + +
Sbjct: 17 EAAEEDPAAAFLAQQESEIAGIENDSGFGAPAASQVASAQPGLASGGGSEDMGTT-VNGD 75
Query: 186 EFQENSSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDEEELERMRILEKDAK 365
FQE + P+ + + + EPE I WR E ++R+ + D + + AK
Sbjct: 76 VFQEANG--PADGYAAIAQADRLTQEPESIRKWREEQKKRLQELDAASKVTEQEWREKAK 133
Query: 366 KELDDWNSHHNEQLLNKRKLNRE-------------------TQGVFVKERDQPIPGSEW 488
K+L++WN +EQ + K K+N ++ FVKE + PG+EW
Sbjct: 134 KDLEEWNQRQSEQ-VEKNKINNRIADKAFYQQPDADTIGYVASEEAFVKESKEETPGTEW 192
Query: 489 QRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDTSRMKSILLSLKTDPLVR 644
++V ++C+FN +S KD SR++S+L+SLK PL R
Sbjct: 193 EKVAQLCDFNPKSSKQC---------------KDVSRLRSVLMSLKQTPLSR 229
>sp|P08081|CLCA_RAT Clathrin light chain A (Lca)
Length = 248
Score = 80.1 bits (196), Expect = 6e-15
Identities = 63/237 (26%), Positives = 102/237 (43%), Gaps = 31/237 (13%)
Frame = +3
Query: 24 DLIADFLAREQEQLGDID-DFKFDEINHDSFNSQVDGFETFPDSNDYASNDFTSNEFQEN 200
D A FLA+++ ++ I+ D F ++ + Q G P D +QE+
Sbjct: 30 DPAAAFLAQQESEIAGIENDEAFAILDGGAPGPQAHGEP--PGGPDAVDGVMNGEYYQES 87
Query: 201 SSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDD 380
+ P+ ++ + EV + EPE I WR E ER+ D ++ ++ A KEL++
Sbjct: 88 NG--PTDSYAAISEVDRLQSEPESIRKWREEQTERLEALDANSRKQEAEWKEKAVKELEE 145
Query: 381 WNSHHNEQLLNKRKLNR------------------------------ETQGVFVKERDQP 470
W + +EQL + NR + FV + D+
Sbjct: 146 WYARQDEQLQKTKASNRVADEAFYKQPFADVIGYVTNINHPCYSLEQAAEEAFVNDIDES 205
Query: 471 IPGSEWQRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDTSRMKSILLSLKTDPLV 641
PG+EW+RV ++C+FN +S KD SRM+S+L+SLK PLV
Sbjct: 206 SPGTEWERVARLCDFNPKSSKQA---------------KDVSRMRSVLISLKQAPLV 247
>sp|P04975|CLCB_BOVIN Clathrin light chain B (Lcb)
Length = 228
Score = 79.0 bits (193), Expect = 1e-14
Identities = 63/237 (26%), Positives = 103/237 (43%), Gaps = 25/237 (10%)
Frame = +3
Query: 9 QAIMSDLIADFLAREQEQLGDIDDFKFDEINHDSFNSQV--DGFETFPDSNDYASNDF-- 176
+A D A FLA+++ ++ I+ N + F + G P AS D
Sbjct: 17 EAAEEDPAAAFLAQQESEIAGIE-------NDEGFGAPAGSQGGLAQPGPASGASEDMGA 69
Query: 177 --TSNEFQENSSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDEEELERMRIL 350
+ FQE + P+ + + + EPE I WR E +R+ + D +
Sbjct: 70 TVNGDVFQEANG--PADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAASKVMEQEW 127
Query: 351 EKDAKKELDDWNSHHNEQLLNKRKLNRE-------------------TQGVFVKERDQPI 473
+ AKK+L++WN +EQ + K K+N ++ FVKE +
Sbjct: 128 REKAKKDLEEWNQRQSEQ-VEKNKINNRIADKAFYQQPDADIIGYVASEEAFVKESKEET 186
Query: 474 PGSEWQRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDTSRMKSILLSLKTDPLVR 644
PG+EW++V ++C+FN +S KD SR++S+L+SLK PL R
Sbjct: 187 PGTEWEKVAQLCDFNPKSSKQC---------------KDVSRLRSVLMSLKQTPLSR 228
>sp|P09497|CLCB_HUMAN Clathrin light chain B (Lcb)
Length = 229
Score = 78.2 bits (191), Expect = 2e-14
Identities = 58/231 (25%), Positives = 101/231 (43%), Gaps = 19/231 (8%)
Frame = +3
Query: 9 QAIMSDLIADFLAREQEQLGDIDDFKFDEINHDSFNSQVDGFETFPDSNDYASNDFTSNE 188
+A D A FLA+++ ++ I++ + S + T ++ +
Sbjct: 17 EAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHAAPAQPGPTSGAGSEDMGTTVNGDV 76
Query: 189 FQENSSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDEEELERMRILEKDAKK 368
FQE + P+ + + + EPE I WR E +R+ + D + + AKK
Sbjct: 77 FQEANG--PADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKK 134
Query: 369 ELDDWNSHHNEQLLNKRKLNRE-------------------TQGVFVKERDQPIPGSEWQ 491
+L++WN +EQ + K K+N ++ FVKE + PG+EW+
Sbjct: 135 DLEEWNQRQSEQ-VEKNKINNRIADKAFYQQPDADIIGYVASEEAFVKESKEETPGTEWE 193
Query: 492 RVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDTSRMKSILLSLKTDPLVR 644
+V ++C+FN +S KD SR++S+L+SLK PL R
Sbjct: 194 KVAQLCDFNPKSSKQC---------------KDVSRLRSVLMSLKQTPLSR 229
>sp|P09496|CLCA_HUMAN Clathrin light chain A (Lca)
Length = 248
Score = 77.0 bits (188), Expect = 5e-14
Identities = 62/237 (26%), Positives = 102/237 (43%), Gaps = 31/237 (13%)
Frame = +3
Query: 24 DLIADFLAREQEQLGDID-DFKFDEINHDSFNSQVDGFETFPDSNDYASNDFTSNEFQEN 200
D A FLA+++ ++ I+ D F ++ + Q G P D +QE+
Sbjct: 30 DPAAAFLAQQESEIAGIENDEAFAILDGGAPGPQPHGEP--PGGPDAVDGVMNGEYYQES 87
Query: 201 SSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDD 380
+ P+ ++ + +V + EPE I WR E ER+ D ++ ++ A KEL++
Sbjct: 88 NG--PTDSYAAISQVDRLQSEPESIRKWREEQMERLEALDANSRKQEAEWKEKAIKELEE 145
Query: 381 WNSHHNEQLLNKRKLNR------------------------------ETQGVFVKERDQP 470
W + +EQL + NR + FV + D+
Sbjct: 146 WYARQDEQLQKTKANNRVADEAFYKQPFADVIGYVTNINHPCYSLEQAAEEAFVNDIDES 205
Query: 471 IPGSEWQRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDTSRMKSILLSLKTDPLV 641
PG+EW+RV ++C+FN +S KD SRM+S+L+SLK PLV
Sbjct: 206 SPGTEWERVARLCDFNPKSSKQA---------------KDVSRMRSVLISLKQAPLV 247
>sp|Q9USP6|CLC1_SCHPO Clathrin light chain (CLC)
Length = 229
Score = 50.8 bits (120), Expect = 4e-06
Identities = 53/213 (24%), Positives = 91/213 (42%), Gaps = 14/213 (6%)
Frame = +3
Query: 36 DFLAREQEQLG-DIDDFKFDE-------INHDSFNSQVDGFETFP--DSNDYASNDFTSN 185
DFL RE+ LG D F+ E +DS Q + FP D+ AS F++
Sbjct: 27 DFLEREKLALGEDAGQFETPEDKDALLNFENDSEAEQTRFEQNFPPIDAEMQASGTFSA- 85
Query: 186 EFQENSSYLPSTNFDSRPEVSIPRIE---PEKILVWRREFEERILKKDEEELERMRILEK 356
P + + EV P E PE + W+ + +RI ++DE + +
Sbjct: 86 ---------PKAPYMGQAEVHPPEDESGDPEPVRKWKEDQMKRIQERDESSKKLRESNIE 136
Query: 357 DAKKELDDWNSHHNEQLLNKRKLNRETQGVFVKERDQPIPG-SEWQRVCKMCEFNTRSGV 533
A+K +DD+ + N++ +R+ Q ++E + G + W+R+ K+ + +
Sbjct: 137 KARKAIDDFYENFNDKRDKVIAKSRKEQEKLLEENESKSTGTTSWERILKLIDLSD---- 192
Query: 534 TVKPVAPGGEGIPVYTPKDTSRMKSILLSLKTD 632
KP A G + T R + +L+SL D
Sbjct: 193 --KPEAHG---------RSTERFRELLISLAKD 214
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,416,766
Number of Sequences: 369166
Number of extensions: 1519254
Number of successful extensions: 5801
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5288
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5744
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7357347200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)