Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_006_P07
(827 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O08585|CLCA_MOUSE Clathrin light chain A (Lca) 74 5e-13
sp|Q9VWA1|CLC_DROME Clathrin light chain (dClc) 74 5e-13
sp|P08082|CLCB_RAT Clathrin light chain B (Lcb) 71 4e-12
sp|P08081|CLCA_RAT Clathrin light chain A (Lca) 71 4e-12
sp|Q6IRU5|CLCB_MOUSE Clathrin light chain B (Lcb) 71 4e-12
sp|P09497|CLCB_HUMAN Clathrin light chain B (Lcb) 70 5e-12
sp|P04975|CLCB_BOVIN Clathrin light chain B (Lcb) 70 5e-12
sp|P04973|CLCA_BOVIN Clathrin light chain A (Lca) 70 7e-12
sp|P09496|CLCA_HUMAN Clathrin light chain A (Lca) 69 2e-11
sp|Q9USP6|CLC1_SCHPO Clathrin light chain (CLC) 44 4e-04
>sp|O08585|CLCA_MOUSE Clathrin light chain A (Lca)
Length = 235
Score = 73.9 bits (180), Expect = 5e-13
Identities = 55/184 (29%), Positives = 83/184 (45%), Gaps = 18/184 (9%)
Frame = +3
Query: 168 PDSNDYASNDFTSNEFQENSSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDE 347
PD+ D N +QE++ P+ ++ + EV + EPE I WR E ER+ D
Sbjct: 71 PDAVDGVMN---GEYYQESNG--PTDSYAAISEVDRLQSEPESIRKWREEQTERLEALDA 125
Query: 348 EELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRETQGVFVKER-------------- 485
++ ++ A KEL++W + +EQL + NR + F K+
Sbjct: 126 NSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRAAEEAFYKQPFADVIGYVAAEEAF 185
Query: 486 ----DQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDTSRMRSILHSLKT 653
D+ PG+EW+RV +C+FN +S KD SRMRS+L SLK
Sbjct: 186 VNDIDESSPGTEWERVAPLCDFNPKSSKQA---------------KDVSRMRSVLISLKQ 230
Query: 654 DLLV 665
LV
Sbjct: 231 APLV 234
>sp|Q9VWA1|CLC_DROME Clathrin light chain (dClc)
Length = 219
Score = 73.9 bits (180), Expect = 5e-13
Identities = 51/127 (40%), Positives = 67/127 (52%), Gaps = 3/127 (2%)
Frame = +3
Query: 279 RIEPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKL--- 449
R EPEKI WR E ++R+ +KD EE + L + +KKELDDW E ++K KL
Sbjct: 100 REEPEKIRKWREEQKQRLEEKDIEEERKKEELRQQSKKELDDWLRQIGES-ISKTKLASR 158
Query: 450 NRETQGVFVKERDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDTSRMR 629
N E Q + E PG+EW+R+ K+C+FN + V G KD SRMR
Sbjct: 159 NAEKQAATL-ENGTIEPGTEWERIAKLCDFNPK-------VNKAG--------KDVSRMR 202
Query: 630 SILHSLK 650
SI LK
Sbjct: 203 SIYLHLK 209
>sp|P08082|CLCB_RAT Clathrin light chain B (Lcb)
Length = 229
Score = 70.9 bits (172), Expect = 4e-12
Identities = 45/147 (30%), Positives = 69/147 (46%), Gaps = 19/147 (12%)
Frame = +3
Query: 285 EPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRE-- 458
EPE I WR E ++R+ + D + + AKK+L++WN +EQ + K K+N
Sbjct: 99 EPESIRKWREEQKKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQ-VEKNKINNRIA 157
Query: 459 -----------------TQGVFVKERDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGE 587
++ FVKE + PG+EW++V ++C+FN +S
Sbjct: 158 DKAFYQQPDADTIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQC-------- 209
Query: 588 GIPVYTPKDTSRMRSILHSLKTDLLVR 668
KD SR+RS+L SLK L R
Sbjct: 210 -------KDVSRLRSVLMSLKQTPLSR 229
>sp|P08081|CLCA_RAT Clathrin light chain A (Lca)
Length = 248
Score = 70.9 bits (172), Expect = 4e-12
Identities = 55/196 (28%), Positives = 84/196 (42%), Gaps = 30/196 (15%)
Frame = +3
Query: 168 PDSNDYASNDFTSNEFQENSSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDE 347
PD+ D N +QE++ P+ ++ + EV + EPE I WR E ER+ D
Sbjct: 72 PDAVDGVMN---GEYYQESNG--PTDSYAAISEVDRLQSEPESIRKWREEQTERLEALDA 126
Query: 348 EELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNR------------------------ 455
++ ++ A KEL++W + +EQL + NR
Sbjct: 127 NSRKQEAEWKEKAVKELEEWYARQDEQLQKTKASNRVADEAFYKQPFADVIGYVTNINHP 186
Query: 456 ------ETQGVFVKERDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDT 617
+ FV + D+ PG+EW+RV ++C+FN +S KD
Sbjct: 187 CYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQA---------------KDV 231
Query: 618 SRMRSILHSLKTDLLV 665
SRMRS+L SLK LV
Sbjct: 232 SRMRSVLISLKQAPLV 247
>sp|Q6IRU5|CLCB_MOUSE Clathrin light chain B (Lcb)
Length = 229
Score = 70.9 bits (172), Expect = 4e-12
Identities = 45/147 (30%), Positives = 69/147 (46%), Gaps = 19/147 (12%)
Frame = +3
Query: 285 EPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRE-- 458
EPE I WR E ++R+ + D + + AKK+L++WN +EQ + K K+N
Sbjct: 99 EPESIRKWREEQKKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQ-VEKNKINNRIA 157
Query: 459 -----------------TQGVFVKERDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGE 587
++ FVKE + PG+EW++V ++C+FN +S
Sbjct: 158 DKAFYQQPDADTIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQC-------- 209
Query: 588 GIPVYTPKDTSRMRSILHSLKTDLLVR 668
KD SR+RS+L SLK L R
Sbjct: 210 -------KDVSRLRSVLMSLKQTPLSR 229
>sp|P09497|CLCB_HUMAN Clathrin light chain B (Lcb)
Length = 229
Score = 70.5 bits (171), Expect = 5e-12
Identities = 45/147 (30%), Positives = 68/147 (46%), Gaps = 19/147 (12%)
Frame = +3
Query: 285 EPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRE-- 458
EPE I WR E +R+ + D + + AKK+L++WN +EQ + K K+N
Sbjct: 99 EPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQ-VEKNKINNRIA 157
Query: 459 -----------------TQGVFVKERDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGE 587
++ FVKE + PG+EW++V ++C+FN +S
Sbjct: 158 DKAFYQQPDADIIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQC-------- 209
Query: 588 GIPVYTPKDTSRMRSILHSLKTDLLVR 668
KD SR+RS+L SLK L R
Sbjct: 210 -------KDVSRLRSVLMSLKQTPLSR 229
>sp|P04975|CLCB_BOVIN Clathrin light chain B (Lcb)
Length = 228
Score = 70.5 bits (171), Expect = 5e-12
Identities = 45/147 (30%), Positives = 68/147 (46%), Gaps = 19/147 (12%)
Frame = +3
Query: 285 EPEKILVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRE-- 458
EPE I WR E +R+ + D + + AKK+L++WN +EQ + K K+N
Sbjct: 98 EPESIRKWREEQRKRLQELDAASKVMEQEWREKAKKDLEEWNQRQSEQ-VEKNKINNRIA 156
Query: 459 -----------------TQGVFVKERDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGE 587
++ FVKE + PG+EW++V ++C+FN +S
Sbjct: 157 DKAFYQQPDADIIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQC-------- 208
Query: 588 GIPVYTPKDTSRMRSILHSLKTDLLVR 668
KD SR+RS+L SLK L R
Sbjct: 209 -------KDVSRLRSVLMSLKQTPLSR 228
>sp|P04973|CLCA_BOVIN Clathrin light chain A (Lca)
Length = 243
Score = 70.1 bits (170), Expect = 7e-12
Identities = 54/196 (27%), Positives = 86/196 (43%), Gaps = 30/196 (15%)
Frame = +3
Query: 168 PDSNDYASNDFTSNEFQENSSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDE 347
PD+ D +N + +QE++ P+ ++ + +V + EPE I WR E ER+ D
Sbjct: 67 PDAVDGVTN---GDYYQESNG--PTDSYAAISQVDRLQSEPESIRKWREEQTERLEALDA 121
Query: 348 EELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNR------------------------ 455
++ ++ A KELD+W + +EQL + NR
Sbjct: 122 NSRKQEAEWKEKAIKELDEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYVTNINHP 181
Query: 456 ------ETQGVFVKERDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDT 617
+ FV + ++ PG+EW+RV ++C+FN +S KD
Sbjct: 182 CYSLEQAAEEAFVNDIEESSPGTEWERVARLCDFNPKSSKQA---------------KDV 226
Query: 618 SRMRSILHSLKTDLLV 665
SRMRS+L SLK LV
Sbjct: 227 SRMRSVLISLKQAPLV 242
>sp|P09496|CLCA_HUMAN Clathrin light chain A (Lca)
Length = 248
Score = 68.6 bits (166), Expect = 2e-11
Identities = 54/196 (27%), Positives = 84/196 (42%), Gaps = 30/196 (15%)
Frame = +3
Query: 168 PDSNDYASNDFTSNEFQENSSYLPSTNFDSRPEVSIPRIEPEKILVWRREFEERILKKDE 347
PD+ D N +QE++ P+ ++ + +V + EPE I WR E ER+ D
Sbjct: 72 PDAVDGVMN---GEYYQESNG--PTDSYAAISQVDRLQSEPESIRKWREEQMERLEALDA 126
Query: 348 EELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNR------------------------ 455
++ ++ A KEL++W + +EQL + NR
Sbjct: 127 NSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGYVTNINHP 186
Query: 456 ------ETQGVFVKERDQPIPGSEWQRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDT 617
+ FV + D+ PG+EW+RV ++C+FN +S KD
Sbjct: 187 CYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQA---------------KDV 231
Query: 618 SRMRSILHSLKTDLLV 665
SRMRS+L SLK LV
Sbjct: 232 SRMRSVLISLKQAPLV 247
>sp|Q9USP6|CLC1_SCHPO Clathrin light chain (CLC)
Length = 229
Score = 44.3 bits (103), Expect = 4e-04
Identities = 41/180 (22%), Positives = 76/180 (42%), Gaps = 11/180 (6%)
Frame = +3
Query: 150 DGFETFPDSNDYASNDFTSN------EFQENSSY-LPSTNFDSRPEVSIPRIE---PEKI 299
D F + ++ F N E Q + ++ P + + EV P E PE +
Sbjct: 50 DALLNFENDSEAEQTRFEQNFPPIDAEMQASGTFSAPKAPYMGQAEVHPPEDESGDPEPV 109
Query: 300 LVWRREFEERILKKDEEELERMRILEKDAKKELDDWNSHHNEQLLNKRKLNRETQGVFVK 479
W+ + +RI ++DE + + A+K +DD+ + N++ +R+ Q ++
Sbjct: 110 RKWKEDQMKRIQERDESSKKLRESNIEKARKAIDDFYENFNDKRDKVIAKSRKEQEKLLE 169
Query: 480 ERDQPIPG-SEWQRVCKMCEFNTRSGVTVKPVAPGGEGIPVYTPKDTSRMRSILHSLKTD 656
E + G + W+R+ K+ + + KP A G + T R R +L SL D
Sbjct: 170 ENESKSTGTTSWERILKLIDLSD------KPEAHG---------RSTERFRELLISLAKD 214
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,667,410
Number of Sequences: 369166
Number of extensions: 1575639
Number of successful extensions: 5829
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5307
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5768
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8004331590
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)