Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00190 (1822 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q7PLI2|NIPB_DROME Nipped-B protein (SCC2 homolog) 121 8e-27 sp|Q6KC79|NIPBL_HUMAN Nipped-B-like protein (Delangin) (SCC... 117 1e-25 sp|Q6KCD5|NPBL_MOUSE Nipped-B-like protein (Delangin homolo... 117 1e-25 sp|Q95XZ5|NPBL_CAEEL Nipped-B-like protein pqn-85 (Prion-li... 89 3e-17 sp|Q00333|NPBL_COPCI Rad9 protein (SCC2 homolog) 74 1e-12 sp|Q09725|MIS4_SCHPO Sister chromatid cohesion protein mis4... 63 2e-09 sp|P24408|RAB9A_CANFA Ras-related protein Rab-9A (Rab-9) 43 0.003 sp|P51151|RAB9A_HUMAN Ras-related protein Rab-9A (Rab-9) 43 0.003 sp|Q9R0M6|RAB9A_MOUSE Ras-related protein Rab-9A (Rab-9) (S... 43 0.003 sp|Q99P75|RAB9A_RAT Ras-related protein Rab-9A (Rab-9) 43 0.003
>sp|Q7PLI2|NIPB_DROME Nipped-B protein (SCC2 homolog) Length = 2077 Score = 121 bits (303), Expect = 8e-27 Identities = 56/115 (48%), Positives = 83/115 (72%) Frame = +3 Query: 1425 LTVREATVDLIGKFLIQKPELLNQYYHVLVNRIVDTGTSVRKRVIKALWDICSSQNDFTN 1604 ++VREA VDL+GKF++ +L++QYY +L RI+DTG SVRKRVIK L DIC DF+ Sbjct: 1182 ISVREAAVDLVGKFVLSNQDLIDQYYDMLSTRILDTGVSVRKRVIKILRDICLEYPDFSK 1241 Query: 1605 CAEVYAKIMKRMYDEESIKKLVNEVFNSIWFSPINDKDPVKLQQRIFSIADVIHS 1769 E+ K+++R++DEE I+KLV EVF +WF+P D + +Q++I I DV+++ Sbjct: 1242 IPEICVKMIRRVHDEEGIQKLVTEVFMKMWFTPCTKNDKIGIQRKINHIIDVVNT 1296
>sp|Q6KC79|NIPBL_HUMAN Nipped-B-like protein (Delangin) (SCC2 homolog) Length = 2804 Score = 117 bits (293), Expect = 1e-25 Identities = 55/112 (49%), Positives = 78/112 (69%) Frame = +3 Query: 1428 TVREATVDLIGKFLIQKPELLNQYYHVLVNRIVDTGTSVRKRVIKALWDICSSQNDFTNC 1607 +VREA V+L+G+F++ +P+L QYY +L+ RI+DTG SVRKRVIK L DIC Q F Sbjct: 1826 SVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKI 1885 Query: 1608 AEVYAKIMKRMYDEESIKKLVNEVFNSIWFSPINDKDPVKLQQRIFSIADVI 1763 E+ K+++R+ DEE IKKLVNE F +WF+P D + ++I +I DV+ Sbjct: 1886 TEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVV 1937
>sp|Q6KCD5|NPBL_MOUSE Nipped-B-like protein (Delangin homolog) (SCC2 homolog) Length = 2798 Score = 117 bits (293), Expect = 1e-25 Identities = 55/112 (49%), Positives = 78/112 (69%) Frame = +3 Query: 1428 TVREATVDLIGKFLIQKPELLNQYYHVLVNRIVDTGTSVRKRVIKALWDICSSQNDFTNC 1607 +VREA V+L+G+F++ +P+L QYY +L+ RI+DTG SVRKRVIK L DIC Q F Sbjct: 1820 SVREAAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKI 1879 Query: 1608 AEVYAKIMKRMYDEESIKKLVNEVFNSIWFSPINDKDPVKLQQRIFSIADVI 1763 E+ K+++R+ DEE IKKLVNE F +WF+P D + ++I +I DV+ Sbjct: 1880 TEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVV 1931
>sp|Q95XZ5|NPBL_CAEEL Nipped-B-like protein pqn-85 (Prion-like-(Q/n-rich)-domain-bearing protein 85) (SCC2 homolog) Length = 2203 Score = 89.4 bits (220), Expect = 3e-17 Identities = 39/95 (41%), Positives = 65/95 (68%) Frame = +3 Query: 1431 VREATVDLIGKFLIQKPELLNQYYHVLVNRIVDTGTSVRKRVIKALWDICSSQNDFTNCA 1610 VRE+ V+LIG+F++ E + +YY + RI+DTG +VRKRVI+ + +IC F Sbjct: 1364 VRESAVELIGRFVLYDEEYVRKYYSQIAERILDTGVAVRKRVIRIMREICEKFPTFEMIP 1423 Query: 1611 EVYAKIMKRMYDEESIKKLVNEVFNSIWFSPINDK 1715 ++ A++++R+ DEE +KKLV E F ++WF P++ + Sbjct: 1424 DMLARMIRRVTDEEGVKKLVFETFTTLWFQPVDTR 1458
>sp|Q00333|NPBL_COPCI Rad9 protein (SCC2 homolog) Length = 2157 Score = 74.3 bits (181), Expect = 1e-12 Identities = 37/102 (36%), Positives = 59/102 (57%), Gaps = 1/102 (0%) Frame = +3 Query: 1431 VREATVDLIGKFLIQKPELLNQYYHVLVNRIVDTGTSVRKRVIKALWDICSSQNDFTNCA 1610 VR+A V+LIGK++I PE+ YY + R+ DTG +VRKRVIK L +D Sbjct: 1264 VRDAAVELIGKYMIDSPEVAGNYYQKIAERMADTGLAVRKRVIKLLKSYYGVIDDAQRKI 1323 Query: 1611 EVYAKIMKRMYDE-ESIKKLVNEVFNSIWFSPINDKDPVKLQ 1733 ++ A+++ RM DE + +K L + +WF P+ +K++ Sbjct: 1324 DISARLVLRMVDEDDGVKDLAMKTLEELWFPPLPPPSGMKVK 1365
>sp|Q09725|MIS4_SCHPO Sister chromatid cohesion protein mis4 (SCC2 homolog) Length = 1583 Score = 63.2 bits (152), Expect = 2e-09 Identities = 32/96 (33%), Positives = 56/96 (58%), Gaps = 1/96 (1%) Frame = +3 Query: 1431 VREATVDLIGKFLIQKPELLNQYYHVLVNRIVDTGTSVRKRVIKALWDICSSQNDFTNCA 1610 VR+ +DL+G +++ E + Q Y +++ I D T VRKR IK L ++ + D Sbjct: 830 VRDTVLDLLGTYIMAYRETIPQIYGCIISGISDPSTIVRKRAIKQLCEVYEATEDLNIRV 889 Query: 1611 EVYAKIMKRMYD-EESIKKLVNEVFNSIWFSPINDK 1715 ++ +K++ R D EE+I +L EV +WFSP +++ Sbjct: 890 DIASKLLTRSNDEEETISELSLEVLEKLWFSPASNE 925
>sp|P24408|RAB9A_CANFA Ras-related protein Rab-9A (Rab-9) Length = 201 Score = 42.7 bits (99), Expect = 0.003 Identities = 18/44 (40%), Positives = 26/44 (59%) Frame = +2 Query: 1349 IRAYFVALQLWDTAGQERFRSTAVSAYSSRGYC*FNWKIFDSKT 1480 + +FV +Q+WDTAGQERFRS Y C + + DS++ Sbjct: 51 VDGHFVTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQS 94
>sp|P51151|RAB9A_HUMAN Ras-related protein Rab-9A (Rab-9) Length = 201 Score = 42.7 bits (99), Expect = 0.003 Identities = 18/44 (40%), Positives = 26/44 (59%) Frame = +2 Query: 1349 IRAYFVALQLWDTAGQERFRSTAVSAYSSRGYC*FNWKIFDSKT 1480 + +FV +Q+WDTAGQERFRS Y C + + DS++ Sbjct: 51 VDGHFVTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQS 94
>sp|Q9R0M6|RAB9A_MOUSE Ras-related protein Rab-9A (Rab-9) (Sid 99) Length = 201 Score = 42.7 bits (99), Expect = 0.003 Identities = 18/44 (40%), Positives = 26/44 (59%) Frame = +2 Query: 1349 IRAYFVALQLWDTAGQERFRSTAVSAYSSRGYC*FNWKIFDSKT 1480 + +FV +Q+WDTAGQERFRS Y C + + DS++ Sbjct: 51 VDGHFVTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQS 94
>sp|Q99P75|RAB9A_RAT Ras-related protein Rab-9A (Rab-9) Length = 201 Score = 42.7 bits (99), Expect = 0.003 Identities = 18/44 (40%), Positives = 26/44 (59%) Frame = +2 Query: 1349 IRAYFVALQLWDTAGQERFRSTAVSAYSSRGYC*FNWKIFDSKT 1480 + +FV +Q+WDTAGQERFRS Y C + + DS++ Sbjct: 51 VDGHFVTMQIWDTAGQERFRSLRTPFYRGSDCCLLTFSVDDSQS 94
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 199,254,686 Number of Sequences: 369166 Number of extensions: 4080728 Number of successful extensions: 10944 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 9955 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 10931 length of database: 68,354,980 effective HSP length: 117 effective length of database: 46,740,985 effective search space used: 22856341665 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)