Planaria EST Database

DrC_00027

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00027
         (1792 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q29099|PTBP1_PIG  Polypyrimidine tract-binding protein 1 ...   229   2e-59
sp|Q00438|PTBP1_RAT  Polypyrimidine tract-binding protein 1 ...   229   3e-59
sp|Q8BHD7|ROD1_MOUSE  Regulator of differentiation 1 (Rod1)       224   6e-58
sp|P26599|PTBP1_HUMAN  Polypyrimidine tract-binding protein ...   146   2e-34
sp|Q9Z118|ROD1_RAT  Regulator of differentiation 1 (Rod1)         131   6e-30
sp|O95758|ROD1_HUMAN  Regulator of differentiation 1 (Rod1)       131   6e-30
sp|P17225|PTBP1_MOUSE  Polypyrimidine tract-binding protein ...   119   2e-26
sp|Q8WVV9|HNRLL_HUMAN  Heterogeneous nuclear ribonucleoprote...   107   9e-23
sp|Q921F4|HNRLL_MOUSE  Heterogeneous nuclear ribonucleoprote...   107   1e-22
sp|P14866|HNRPL_HUMAN  Heterogeneous nuclear ribonucleoprote...    71   1e-11

>sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
            ribonucleoprotein I) (hnRNP I)
          Length = 557

 Score =  229 bits (584), Expect = 2e-59
 Identities = 173/546 (31%), Positives = 260/546 (47%), Gaps = 26/546 (4%)
 Frame = +2

Query: 83   SDNEDSKKIRRE-----IPASKVLHIRSLPDDVTELEIASVATPFGHISYMVLTRKTGQA 247
            ++  DSKK + +     +P S+V+HIR LP DVTE E+ S+  PFG ++ +++ +   QA
Sbjct: 39   ANGNDSKKFKGDNRSAGVP-SRVIHIRKLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQA 97

Query: 248  LLEMETKDIAETMFEYYQRHAPHLRNKRCFVQYXXXXXXXXXXXXXXPEAENAVTTANQI 427
             +EM T++ A TM  YY    P LR +  ++Q+                A+ A+   N +
Sbjct: 98   FIEMNTEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSV 157

Query: 428  CD--------------SMAKESSGPVLRLVVDNWNHEKITNLHLFKIFQHYGILERIVIY 565
                             MA     PVLR++V+N  +  +T   L +IF  +G + +I+ +
Sbjct: 158  QSGNLALAASAAAVDAGMAMAGQSPVLRIIVENLFY-PVTLDVLHQIFSKFGTVLKIITF 216

Query: 566  VSKGVVQGFIQYSDPFSAKVAKALTNELCIFPRSCIMRVNFSNRQSLDISREDDLVRDFV 745
                  Q  +QY+DP SA+ AK   +   I+   C +R++FS   SL++   +D  RD+ 
Sbjct: 217  TKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYT 276

Query: 746  RHPVSPQELKNVHVNIGGGVMKDVEXXXXXXXXXXXXXTXXXXXXXXXXXXNHPDDAMPL 925
            R P  P                D +                            P  A+P 
Sbjct: 277  R-PDLPS--------------GDNQPSLDQTMAAAFGAPGIMSASPYAGAGFPPTFAIPQ 321

Query: 926  LRSIA-PAIRGFLDNQDILSRDFSRNDRNDAYGRTHF----GEKTSPLLIVSNLNEAKIH 1090
              +++ P + G L    I     S   R  A GR       G   S LL VSNLN  ++ 
Sbjct: 322  AATVSVPNVHGALAPLAIP----SAAARAAAAGRIAIPGLAGAGNSVLL-VSNLNPERVT 376

Query: 1091 PDALFKLFGCYGDVTRVKIMYNRKNTALVQFANEEFAQRALQYLNGVNLYGKPLHVNFSK 1270
            P +LF LFG Y DV RVKI++N+K  ALVQ A+   AQ A+ +LNG  L+GKP+ +  SK
Sbjct: 377  PQSLFILFGVYCDVQRVKILFNKKENALVQMADGSQAQLAMSHLNGHKLHGKPVRITLSK 436

Query: 1271 HDRISHRAPIAGSEEEASGDRLHKEYVDSKLHRFKRSQSRNHANIYEPSKVLHIAGLVDD 1450
            H  +  + P  G E++     L K+Y +S LHRFK+  S+N  NI+ PS  LH++ +   
Sbjct: 437  HQNV--QLpreGQEDQG----LTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPS 490

Query: 1451 VSEEDIEALFQDNKFRVRKIRMFNSNGKKMXXXXXXXXXXXXXXXXXLHDYDLCGSN--L 1624
            +SEED++ LF  N   V+  + F  + +KM                 LH++DL G N  L
Sbjct: 491  ISEEDLKILFSSNGGIVKGFKFFQKD-RKMALIQMGSVEEAIQALIDLHNHDL-GENHHL 548

Query: 1625 RVSFSK 1642
            RVSFSK
Sbjct: 549  RVSFSK 554

>sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
            ribonucleoprotein I) (hnRNP I) (Pyrimidine-binding
            protein) (PYBP)
          Length = 555

 Score =  229 bits (583), Expect = 3e-59
 Identities = 172/554 (31%), Positives = 261/554 (47%), Gaps = 25/554 (4%)
 Frame = +2

Query: 56   FDAKEEETRSDNEDSKKIRRE-----IPASKVLHIRSLPDDVTELEIASVATPFGHISYM 220
            F      + ++  DSKK + +     +P S+V+H+R LP DVTE E+ S+  PFG ++ +
Sbjct: 29   FIMSSSASAANGNDSKKFKGDNRSTGVP-SRVIHVRKLPSDVTEGEVISLGLPFGKVTNL 87

Query: 221  VLTRKTGQALLEMETKDIAETMFEYYQRHAPHLRNKRCFVQYXXXXXXXXXXXXXXPEAE 400
            ++ +   QA +EM T++ A TM  YY   AP LR +  ++Q+                A+
Sbjct: 88   LMLKGKNQAFIEMSTEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKELKTDSSPNQARAQ 147

Query: 401  NAVTTANQICD--------------SMAKESSGPVLRLVVDNWNHEKITNLHLFKIFQHY 538
             A+   N +                 MA     PVLR++V+N  +  +T   L +IF  +
Sbjct: 148  AALQAVNSVQSGNLALAASAAAVDAGMAMAGQSPVLRIIVENLFY-PVTLDVLHQIFSKF 206

Query: 539  GILERIVIYVSKGVVQGFIQYSDPFSAKVAKALTNELCIFPRSCIMRVNFSNRQSLDISR 718
            G + +I+ +      Q  +QY+DP SA+ AK   +   I+   C +R++FS   SL++  
Sbjct: 207  GTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKY 266

Query: 719  EDDLVRDFVRHPVSPQELKNVHVNIGGGVMKDVEXXXXXXXXXXXXXTXXXXXXXXXXXX 898
             +D  RD+ R P  P           G     ++             +            
Sbjct: 267  NNDKSRDYTR-PDLP----------SGDSQPSLDQTMAAAFGAPGIMSASPYAGAVPSHL 315

Query: 899  NHPDDAMPLLRSIAPAIRGFLDNQDILSRDFSRNDRNDAYGRTHF----GEKTSPLLIVS 1066
             HP  A        P + G L    I S   +      A GR       G   S LL VS
Sbjct: 316  CHPSRA----GLSVPNVHGALAPLAIPSAAAAA----AAAGRIAIPGLAGAGNSVLL-VS 366

Query: 1067 NLNEAKIHPDALFKLFGCYGDVTRVKIMYNRKNTALVQFANEEFAQRALQYLNGVNLYGK 1246
            NLN  ++ P +LF LFG YGDV RVKI++N+K  ALV+ A+   AQ A+ +LNG  L+GK
Sbjct: 367  NLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVEMADGSQAQLAMSHLNGHKLHGK 426

Query: 1247 PLHVNFSKHDRISHRAPIAGSEEEASGDRLHKEYVDSKLHRFKRSQSRNHANIYEPSKVL 1426
             + +  SKH  +  + P  G E++     L K+Y  S LHRFK+  S+N  NI+ PS  L
Sbjct: 427  SVRITLSKHQSV--QLpreGQEDQG----LTKDYGSSPLHRFKKPGSKNFQNIFPPSATL 480

Query: 1427 HIAGLVDDVSEEDIEALFQDNKFRVRKIRMFNSNGKKMXXXXXXXXXXXXXXXXXLHDYD 1606
            H++ +   VSE+D+++LF  N   V+  + F  + +KM                 LH++D
Sbjct: 481  HLSNIPPSVSEDDLKSLFSSNGGVVKGFKFFQKD-RKMALIQMGSVEEAVQALIELHNHD 539

Query: 1607 LCGSN--LRVSFSK 1642
            L G N  LRVSFSK
Sbjct: 540  L-GENHHLRVSFSK 552

>sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1)
          Length = 523

 Score =  224 bits (571), Expect = 6e-58
 Identities = 166/535 (31%), Positives = 259/535 (48%), Gaps = 15/535 (2%)
 Frame = +2

Query: 83   SDNEDSKKIRREIPASKVLHIRSLPDDVTELEIASVATPFGHISYMVLTRKTGQALLEME 262
            +DN+  K  R     S+VLH+R +P DVTE E+ S+  PFG ++ +++ +   QA LEM 
Sbjct: 14   NDNKKFKGDRPPCSPSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMA 73

Query: 263  TKDIAETMFEYYQRHAPHLRNKRCFVQYXXXXXXXXXXXXXXPEAENAVTTANQICD--- 433
            +++ A TM  YY    PHLR++  ++QY                A+ A+   + +     
Sbjct: 74   SEEAAVTMINYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNL 133

Query: 434  ----SMAKESS-----GPVLRLVVDNWNHEKITNLHLFKIFQHYGILERIVIYVSKGVVQ 586
                + A E +      PVLR++++N  +  +T   L +IF  +G + +I+ +      Q
Sbjct: 134  SLPGATANEGTLLPGQSPVLRIIIENLFYP-VTLEVLHQIFSKFGTVLKIITFTKNNQFQ 192

Query: 587  GFIQYSDPFSAKVAKALTNELCIFPRSCIMRVNFSNRQSLDISREDDLVRDFVRHPVSPQ 766
              +QY+DP +A+ AK   +   I+   C +R++FS   SL++   +D  RDF R      
Sbjct: 193  ALLQYADPVNAQYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTR------ 246

Query: 767  ELKNVHVNIGGGVMKDVEXXXXXXXXXXXXXTXXXXXXXXXXXXNHPDDAMPLLRSIA-P 943
                + +  G G    +E             +              P  A P    ++ P
Sbjct: 247  ----LDLPTGDG-QPSLEPPMAAAFGAPGIMSSPYAGAAGFA----PAIAFPQAAGLSVP 297

Query: 944  AIRGFLDNQDILSRDFSRNDRNDAYGRTHFGEKTSPLLIVSNLNEAKIHPDALFKLFGCY 1123
            A+ G L    + S   S   R    G +  G   + +L+V+NLN   I P  LF LFG Y
Sbjct: 298  AVPGALGPLTLTSSAVS--GRMAIPGAS--GMPGNSVLLVTNLNPDFITPHGLFILFGVY 353

Query: 1124 GDVTRVKIMYNRKNTALVQFANEEFAQRALQYLNGVNLYGKPLHVNFSKHDRISHRAPIA 1303
            GDV RVKIM+N+K  ALVQ A+   AQ A+ +L+G  LYGK L    SKH  +  + P  
Sbjct: 354  GDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAV--QLpre 411

Query: 1304 GSEEEASGDRLHKEYVDSKLHRFKRSQSRNHANIYEPSKVLHIAGLVDDVSEEDIEALFQ 1483
            G E++     L K++ +S LHRFK+  S+N  NI+ PS  LH++ +   V+ +D++ LF 
Sbjct: 412  GQEDQG----LTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFT 467

Query: 1484 DNKFRVRKIRMFNSNGKKMXXXXXXXXXXXXXXXXXLHDYDLCGSN--LRVSFSK 1642
            +    V+  + F  + +KM                 LH++DL G N  LRVSFSK
Sbjct: 468  EAGCSVKAFKFFQKD-RKMALIQLGSVEEAIQALIELHNHDL-GENHHLRVSFSK 520

>sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
            ribonucleoprotein I) (hnRNP I) (57 kDa RNA-binding
            protein PPTB-1)
          Length = 531

 Score =  146 bits (369), Expect = 2e-34
 Identities = 85/199 (42%), Positives = 119/199 (59%), Gaps = 2/199 (1%)
 Frame = +2

Query: 1052 LLIVSNLNEAKIHPDALFKLFGCYGDVTRVKIMYNRKNTALVQFANEEFAQRALQYLNGV 1231
            +L+VSNLN  ++ P +LF LFG YGDV RVKI++N+K  ALVQ A+   AQ A+ +LNG 
Sbjct: 338  VLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGNQAQLAMSHLNGH 397

Query: 1232 NLYGKPLHVNFSKHDRISHRAPIAGSEEEASGDRLHKEYVDSKLHRFKRSQSRNHANIYE 1411
             L+GKP+ +  SKH  +  + P  G E++     L K+Y +S LHRFK+  S+N  NI+ 
Sbjct: 398  KLHGKPIRITLSKHQNV--QLpreGQEDQG----LTKDYGNSPLHRFKKPGSKNFQNIFP 451

Query: 1412 PSKVLHIAGLVDDVSEEDIEALFQDNKFRVRKIRMFNSNGKKMXXXXXXXXXXXXXXXXX 1591
            PS  LH++ +   VSEED++ LF  N   V+  + F  + +KM                 
Sbjct: 452  PSATLHLSNIPPSVSEEDLKVLFSSNGGVVKGFKFFQKD-RKMALIQMGSVEEAVQALID 510

Query: 1592 LHDYDLCGSN--LRVSFSK 1642
            LH++DL G N  LRVSFSK
Sbjct: 511  LHNHDL-GENHHLRVSFSK 528


 Score =  117 bits (293), Expect = 1e-25
 Identities = 71/240 (29%), Positives = 119/240 (49%), Gaps = 18/240 (7%)
 Frame = +2

Query: 83  SDNEDSKKIRREIPA----SKVLHIRSLPDDVTELEIASVATPFGHISYMVLTRKTGQAL 250
           ++  DSKK + +  +    S+V+HIR LP DVTE E+ S+  PFG ++ +++ +   QA 
Sbjct: 39  ANGNDSKKFKGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAF 98

Query: 251 LEMETKDIAETMFEYYQRHAPHLRNKRCFVQYXXXXXXXXXXXXXXPEAENAVTTANQIC 430
           +EM T++ A TM  YY    P LR +  ++Q+                A+ A+   N + 
Sbjct: 99  IEMNTEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQ 158

Query: 431 D--------------SMAKESSGPVLRLVVDNWNHEKITNLHLFKIFQHYGILERIVIYV 568
                           MA     PVLR++V+N  +  +T   L +IF  +G + +I+ + 
Sbjct: 159 SGNLALAASAAAVDAGMAMAGQSPVLRIIVENLFY-PVTLDVLHQIFSKFGTVLKIITFT 217

Query: 569 SKGVVQGFIQYSDPFSAKVAKALTNELCIFPRSCIMRVNFSNRQSLDISREDDLVRDFVR 748
                Q  +QY+DP SA+ AK   +   I+   C +R++FS   SL++   +D  RD+ R
Sbjct: 218 KNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTR 277


 Score = 34.3 bits (77), Expect = 1.2
 Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
 Frame = +2

Query: 1121 YGDVTRVKIMYNRKNTALVQFANEEFAQRALQYLNGVN--LYGKPLHVNFSKHDRI 1282
            +G VT + +M   KN A ++   EE A   + Y   V   L G+P+++ FS H  +
Sbjct: 82   FGKVTNL-LMLKGKNQAFIEMNTEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKEL 136


 Score = 33.9 bits (76), Expect = 1.6
 Identities = 29/81 (35%), Positives = 45/81 (55%), Gaps = 6/81 (7%)
 Frame = +2

Query: 1046 SPLL--IVSNLNEAKIHPDALFKLFGCYGDVTRVKIMYNRKNT--ALVQFANEEFAQRAL 1213
            SP+L  IV NL    +  D L ++F  +G V ++ I + + N   AL+Q+A+   AQ A 
Sbjct: 181  SPVLRIIVENLFYP-VTLDVLHQIFSKFGTVLKI-ITFTKNNQFQALLQYADPVSAQHAK 238

Query: 1214 QYLNGVNLYGK--PLHVNFSK 1270
              L+G N+Y     L ++FSK
Sbjct: 239  LSLDGQNIYNACCTLRIDFSK 259

>sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1)
          Length = 523

 Score =  131 bits (330), Expect = 6e-30
 Identities = 81/199 (40%), Positives = 114/199 (57%), Gaps = 2/199 (1%)
 Frame = +2

Query: 1052 LLIVSNLNEAKIHPDALFKLFGCYGDVTRVKIMYNRKNTALVQFANEEFAQRALQYLNGV 1231
            +L+V+NLN   I P  LF LFG YGDV RVKIM+N+K  ALVQ A+   AQ A+ +L+G 
Sbjct: 330  VLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQIAMNHLSGQ 389

Query: 1232 NLYGKPLHVNFSKHDRISHRAPIAGSEEEASGDRLHKEYVDSKLHRFKRSQSRNHANIYE 1411
             LYGK L    SKH  +  + P  G E++     L K++ +S LHRFK+  S+N  NI+ 
Sbjct: 390  RLYGKVLRATLSKHQAV--QLpreGQEDQG----LTKDFSNSPLHRFKKPGSKNFQNIFP 443

Query: 1412 PSKVLHIAGLVDDVSEEDIEALFQDNKFRVRKIRMFNSNGKKMXXXXXXXXXXXXXXXXX 1591
            PS  LH++ +   V+ +D++ LF +    V+  + F  + +KM                 
Sbjct: 444  PSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKD-RKMALIQLGSVEEAIQALIE 502

Query: 1592 LHDYDLCGSN--LRVSFSK 1642
            LH++DL G N  LRVSFSK
Sbjct: 503  LHNHDL-GENHHLRVSFSK 520


 Score =  119 bits (298), Expect = 3e-26
 Identities = 68/234 (29%), Positives = 117/234 (50%), Gaps = 12/234 (5%)
 Frame = +2

Query: 83  SDNEDSKKIRREIPASKVLHIRSLPDDVTELEIASVATPFGHISYMVLTRKTGQALLEME 262
           +DN+  K  R     S+VLH+R +P DVTE E+ S+  PFG ++ +++ +   QA LEM 
Sbjct: 14  NDNKKFKGDRPPCSPSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMA 73

Query: 263 TKDIAETMFEYYQRHAPHLRNKRCFVQYXXXXXXXXXXXXXXPEAENAVTTANQI----- 427
           +++ A TM  YY    PHLR++  ++QY                A+ A+   + +     
Sbjct: 74  SEEAAVTMINYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNL 133

Query: 428 -------CDSMAKESSGPVLRLVVDNWNHEKITNLHLFKIFQHYGILERIVIYVSKGVVQ 586
                   +        PVLR++++N  +  +T   L +IF  +G + +I+ +      Q
Sbjct: 134 SLPGATSNEGTLLPGQSPVLRIIIENLFY-PVTLEVLHQIFSKFGTVLKIITFTKNNQFQ 192

Query: 587 GFIQYSDPFSAKVAKALTNELCIFPRSCIMRVNFSNRQSLDISREDDLVRDFVR 748
             +QY+DP +A+ AK   +   I+   C +R++FS   SL++   +D  RDF R
Sbjct: 193 ALLQYADPVNAQYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTR 246


 Score = 31.6 bits (70), Expect = 7.8
 Identities = 21/63 (33%), Positives = 36/63 (57%), Gaps = 4/63 (6%)
 Frame = +2

Query: 1094 DALFKLFGCYGDVTRVKIMYNRKNT--ALVQFANEEFAQRALQYLNGVNLYGK--PLHVN 1261
            + L ++F  +G V ++ I + + N   AL+Q+A+   AQ A   L+G N+Y     L ++
Sbjct: 167  EVLHQIFSKFGTVLKI-ITFTKNNQFQALLQYADPVNAQYAKMALDGQNIYNACCTLRID 225

Query: 1262 FSK 1270
            FSK
Sbjct: 226  FSK 228

>sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1)
          Length = 521

 Score =  131 bits (330), Expect = 6e-30
 Identities = 81/199 (40%), Positives = 114/199 (57%), Gaps = 2/199 (1%)
 Frame = +2

Query: 1052 LLIVSNLNEAKIHPDALFKLFGCYGDVTRVKIMYNRKNTALVQFANEEFAQRALQYLNGV 1231
            +L+V+NLN   I P  LF LFG YGDV RVKIM+N+K  ALVQ A+   AQ A+ +L+G 
Sbjct: 328  VLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQ 387

Query: 1232 NLYGKPLHVNFSKHDRISHRAPIAGSEEEASGDRLHKEYVDSKLHRFKRSQSRNHANIYE 1411
             LYGK L    SKH  +  + P  G E++     L K++ +S LHRFK+  S+N  NI+ 
Sbjct: 388  RLYGKVLRATLSKHQAV--QLpreGQEDQG----LTKDFSNSPLHRFKKPGSKNFQNIFP 441

Query: 1412 PSKVLHIAGLVDDVSEEDIEALFQDNKFRVRKIRMFNSNGKKMXXXXXXXXXXXXXXXXX 1591
            PS  LH++ +   V+ +D++ LF +    V+  + F  + +KM                 
Sbjct: 442  PSATLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKD-RKMALIQLGSVEEAIQALIE 500

Query: 1592 LHDYDLCGSN--LRVSFSK 1642
            LH++DL G N  LRVSFSK
Sbjct: 501  LHNHDL-GENHHLRVSFSK 518


 Score =  125 bits (313), Expect = 5e-28
 Identities = 73/237 (30%), Positives = 121/237 (51%), Gaps = 15/237 (6%)
 Frame = +2

Query: 83  SDNEDSKKIRREIPA---SKVLHIRSLPDDVTELEIASVATPFGHISYMVLTRKTGQALL 253
           ++  DSKK +R+ P    S+VLH+R +P DVTE EI S+  PFG ++ +++ +   QA L
Sbjct: 9   ANGNDSKKFKRDRPPCSPSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFL 68

Query: 254 EMETKDIAETMFEYYQRHAPHLRNKRCFVQYXXXXXXXXXXXXXXPEAENAVTTANQICD 433
           EM +++ A TM  YY    PHLR++  ++QY                A+ A+   + +  
Sbjct: 69  EMASEEAAVTMVNYYTPITPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQS 128

Query: 434 SMAKESSG------------PVLRLVVDNWNHEKITNLHLFKIFQHYGILERIVIYVSKG 577
                S G            PVLR++++N  +  +T   L +IF  +G + +I+ +    
Sbjct: 129 GSLALSGGPSNEGTVLPGQSPVLRIIIENLFY-PVTLEVLHQIFSKFGTVLKIITFTKNN 187

Query: 578 VVQGFIQYSDPFSAKVAKALTNELCIFPRSCIMRVNFSNRQSLDISREDDLVRDFVR 748
             Q  +QY+DP +A  AK   +   I+   C +R++FS   SL++   +D  RDF R
Sbjct: 188 QFQALLQYADPVNAHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTR 244

>sp|P17225|PTBP1_MOUSE Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
           ribonucleoprotein I) (hnRNP I)
          Length = 527

 Score =  119 bits (299), Expect = 2e-26
 Identities = 73/250 (29%), Positives = 123/250 (49%), Gaps = 19/250 (7%)
 Frame = +2

Query: 56  FDAKEEETRSDNEDSKKIRRE-----IPASKVLHIRSLPDDVTELEIASVATPFGHISYM 220
           F      + ++  DSKK + +     +P S+V+H+R LP DVTE E+ S+  PFG ++ +
Sbjct: 29  FIMSSSASAANGNDSKKFKGDNRSAGVP-SRVIHVRKLPSDVTEGEVISLGLPFGKVTNL 87

Query: 221 VLTRKTGQALLEMETKDIAETMFEYYQRHAPHLRNKRCFVQYXXXXXXXXXXXXXXPEAE 400
           ++ +   QA +EM T++ A TM  YY   AP LR +  ++Q+                A+
Sbjct: 88  LMLKGKNQAFIEMNTEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKELKTDSSPNQVRAQ 147

Query: 401 NAVTTANQICD--------------SMAKESSGPVLRLVVDNWNHEKITNLHLFKIFQHY 538
            A+   N +                 MA     PVLR++V+N  +  +T   L +IF  +
Sbjct: 148 AALQAVNSVQSGNLALAASAAAVDAGMAMAGQSPVLRIIVENLFY-PVTLDVLHQIFSKF 206

Query: 539 GILERIVIYVSKGVVQGFIQYSDPFSAKVAKALTNELCIFPRSCIMRVNFSNRQSLDISR 718
           G + +I+ +      Q  +QY+DP SA+ AK   +   I+   C +R++FS   SL++  
Sbjct: 207 GTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKY 266

Query: 719 EDDLVRDFVR 748
            +D  RD+ R
Sbjct: 267 NNDKSRDYTR 276


 Score =  105 bits (261), Expect = 6e-22
 Identities = 74/203 (36%), Positives = 106/203 (52%), Gaps = 6/203 (2%)
 Frame = +2

Query: 1052 LLIVSNLNEAKIHPDALFKLFGCYGDVTRVKIMYNRKNTALVQFANEEFAQRALQYLNGV 1231
            +L+VSNLN  ++ P +LF LFG YGDV RVKI++N+K  ALVQ A+   AQ         
Sbjct: 336  VLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQ--------- 386

Query: 1232 NLYGKPLHVNFSKHDRISH----RAPIAGSEEEASGDRLHKEYVDSKLHRFKRSQSRNHA 1399
               G+P     +  +  +H     +  A + E      L K+Y  S L RFK+  S+N  
Sbjct: 387  --LGEPPERAQAAREVSAHYTVQASECAAAREGQEDQGLTKDYGSSPL-RFKKPGSKNFQ 443

Query: 1400 NIYEPSKVLHIAGLVDDVSEEDIEALFQDNKFRVRKIRMFNSNGKKMXXXXXXXXXXXXX 1579
            NI+ PS  LH++ +   VSE+D+++LF  N   V+  + F  + +KM             
Sbjct: 444  NIFPPSATLHLSNIPPSVSEDDLKSLFSSNGGVVKGFKFFQKD-RKMALIQMGSVEEAVQ 502

Query: 1580 XXXXLHDYDLCGSN--LRVSFSK 1642
                LH++DL G N  LRVSFSK
Sbjct: 503  ALIELHNHDL-GENHHLRVSFSK 524


 Score = 33.9 bits (76), Expect = 1.6
 Identities = 29/81 (35%), Positives = 45/81 (55%), Gaps = 6/81 (7%)
 Frame = +2

Query: 1046 SPLL--IVSNLNEAKIHPDALFKLFGCYGDVTRVKIMYNRKNT--ALVQFANEEFAQRAL 1213
            SP+L  IV NL    +  D L ++F  +G V ++ I + + N   AL+Q+A+   AQ A 
Sbjct: 180  SPVLRIIVENLFYP-VTLDVLHQIFSKFGTVLKI-ITFTKNNQFQALLQYADPVSAQHAK 237

Query: 1214 QYLNGVNLYGK--PLHVNFSK 1270
              L+G N+Y     L ++FSK
Sbjct: 238  LSLDGQNIYNACCTLRIDFSK 258


 Score = 33.5 bits (75), Expect = 2.1
 Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
 Frame = +2

Query: 1121 YGDVTRVKIMYNRKNTALVQFANEEFAQRALQYLNGVN--LYGKPLHVNFSKHDRI 1282
            +G VT + +M   KN A ++   EE A   + Y   V   L G+P+++ FS H  +
Sbjct: 81   FGKVTNL-LMLKGKNQAFIEMNTEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKEL 135

>sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprotein L-like (Stromal
            RNA-regulating factor) (BLOCK24 protein)
          Length = 542

 Score =  107 bits (268), Expect = 9e-23
 Identities = 104/467 (22%), Positives = 187/467 (40%), Gaps = 8/467 (1%)
 Frame = +2

Query: 116  EIPASKVLHIRSLPDDVTELEIASVATPFGHISYMVLTRKTGQALLEMETKDIAETMFEY 295
            ++  S V+H+R L + V E ++      FG I Y+++     QAL+E E  D A+    +
Sbjct: 71   KVSVSPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTF 130

Query: 296  YQRHAPHLRNKRCFVQYXXXXXXXXXXXXXXPEAENAVTTANQICDSMAKESSGPVLRLV 475
                  ++  ++ F  Y              P   N V         +      P+  + 
Sbjct: 131  AADEPVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKV---------LLLSIQNPLYPIT 181

Query: 476  VDNWNHEKITNLHLFKIFQHYGILERIVIYVSKGVVQGFIQYSDPFSAKVAKALTNELCI 655
            VD           L+ +    G ++RIVI+   G +Q  +++     A+ AKA  N   I
Sbjct: 182  VD----------VLYTVCNPVGKVQRIVIFKRNG-IQAMVEFESVLCAQKAKAALNGADI 230

Query: 656  FPRSCIMRVNFSNRQSLDISREDDLVRDFVRHPVSPQELKNVHVNIGGGVMKDVEXXXXX 835
            +   C +++ ++    L++ R D+   D+ +  +  ++        G G  +        
Sbjct: 231  YAGCCTLKIEYARPTRLNVIRNDNDSWDYTKPYLGRRDR-------GKGRQRQA------ 277

Query: 836  XXXXXXXXTXXXXXXXXXXXXNHPDDAM--------PLLRSIAPAIRGFLDNQDILSRDF 991
                                  HP            PLL   +    G  D  ++++   
Sbjct: 278  ------------------ILGEHPSSFRHDGYGSHGPLLPLPSRYRMGSRDTPELVAYPL 319

Query: 992  SRNDRNDAYGRTHFGEKTSPLLIVSNLNEAKIHPDALFKLFGCYGDVTRVKIMYNRKNTA 1171
             +   +  +G    G  +  +++VS L++ K++   +F LF  YG++ +VK M     TA
Sbjct: 320  PQASSSYMHG----GNPSGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTA 375

Query: 1172 LVQFANEEFAQRALQYLNGVNLYGKPLHVNFSKHDRISHRAPIAGSEEEASGDRLHKEYV 1351
            LV+  +E   +RA+ +LN V L+GK L+V  SK     H    +   E   G   +K++ 
Sbjct: 376  LVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSK----QHSVVPSQIFELEDGTSSYKDFA 431

Query: 1352 DSKLHRFKRSQSRNHANIYEPSKVLHIAGLVDDVSEEDIEALFQDNK 1492
             SK +RF  +   +   I  PS VLH   +   V+EE    L  D++
Sbjct: 432  MSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDHE 478

>sp|Q921F4|HNRLL_MOUSE Heterogeneous nuclear ribonucleoprotein L-like
          Length = 591

 Score =  107 bits (266), Expect = 1e-22
 Identities = 104/467 (22%), Positives = 188/467 (40%), Gaps = 8/467 (1%)
 Frame = +2

Query: 116  EIPASKVLHIRSLPDDVTELEIASVATPFGHISYMVLTRKTGQALLEMETKDIAETMFEY 295
            ++  S V+H+R L + V E ++      FG I Y+++     QAL+E E  D A+    +
Sbjct: 120  KVSVSPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTF 179

Query: 296  YQRHAPHLRNKRCFVQYXXXXXXXXXXXXXXPEAENAVTTANQICDSMAKESSGPVLRLV 475
                  ++  ++ F  Y              P   N V         +      P+  + 
Sbjct: 180  AADVPVYIAGQQAFFNYSTSKRITRPGNTDDPSGGNKV---------LLLSIQNPLYPIT 230

Query: 476  VDNWNHEKITNLHLFKIFQHYGILERIVIYVSKGVVQGFIQYSDPFSAKVAKALTNELCI 655
            VD           L+ +    G ++RIVI+   G +Q  +++     A+ AKA  N   I
Sbjct: 231  VD----------VLYTVCNPVGKVQRIVIFKRNG-IQAMVEFESVLCAQKAKAALNGADI 279

Query: 656  FPRSCIMRVNFSNRQSLDISREDDLVRDFVRHPVSPQELKNVHVNIGGGVMKDVEXXXXX 835
            +   C +++ ++    L++ R D+   D+ +  +  ++        G G  +        
Sbjct: 280  YAGCCTLKIEYARPTRLNVIRNDNDSWDYTKPYLGRRDR-------GKGRQRQA------ 326

Query: 836  XXXXXXXXTXXXXXXXXXXXXNHPDDAM--------PLLRSIAPAIRGFLDNQDILSRDF 991
                                 +HP            PLL   +    G  D  ++++   
Sbjct: 327  ------------------ILGDHPSSFRHDGYGSHGPLLPLPSRYRMGSRDTPELVAYPL 368

Query: 992  SRNDRNDAYGRTHFGEKTSPLLIVSNLNEAKIHPDALFKLFGCYGDVTRVKIMYNRKNTA 1171
             +   +  +G    G  +  +++VS L++ K++   +F LF  YG++ +VK M     TA
Sbjct: 369  PQASSSYMHG----GSPSGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTA 424

Query: 1172 LVQFANEEFAQRALQYLNGVNLYGKPLHVNFSKHDRISHRAPIAGSEEEASGDRLHKEYV 1351
            LV+  +E   +RA+ +LN V L+GK L+V  SK     H    +   E   G   +K++ 
Sbjct: 425  LVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSK----QHSVVPSQIFELEDGTSSYKDFA 480

Query: 1352 DSKLHRFKRSQSRNHANIYEPSKVLHIAGLVDDVSEEDIEALFQDNK 1492
             SK +RF  +   +   I  PS VLH   +   V+EE    L  D++
Sbjct: 481  MSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDHE 527

>sp|P14866|HNRPL_HUMAN Heterogeneous nuclear ribonucleoprotein L (hnRNP L)
          Length = 558

 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 44/140 (31%), Positives = 77/140 (55%)
 Frame = +2

Query: 1046 SPLLIVSNLNEAKIHPDALFKLFGCYGDVTRVKIMYNRKNTALVQFANEEFAQRALQYLN 1225
            SP+L+V  L+++K++ D +F +F  YG+V +VK M ++   A+V+ A+     RA+ +LN
Sbjct: 350  SPVLMVYGLDQSKMNGDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLN 409

Query: 1226 GVNLYGKPLHVNFSKHDRISHRAPIAGSEEEASGDRLHKEYVDSKLHRFKRSQSRNHANI 1405
               ++G+ L+V  SK   I       G E+   G   +K++ +S+ +RF   +      I
Sbjct: 410  NNFMFGQKLNVCVSKQPAIM-PGQSYGLED---GSCSYKDFSESRNNRFSTPEQAAKNRI 465

Query: 1406 YEPSKVLHIAGLVDDVSEED 1465
              PS VLH      +V+EE+
Sbjct: 466  QHPSNVLHFFNAPLEVTEEN 485


 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 60/218 (27%), Positives = 95/218 (43%), Gaps = 3/218 (1%)
 Frame = +2

Query: 122 PASKVLHIRSLPDDVTELEIASVATPFGHISYMVLTRKTGQALLEMETKDIAETMFEYYQ 301
           PAS V+HIR L D V E ++      FG ISY+V+  K  QAL+E E    A     Y  
Sbjct: 68  PASPVVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAA 127

Query: 302 RHAPHLRNKRCFVQYXXXXXXXXXXXXXXPEAENAVTTANQIC---DSMAKESSGPVLRL 472
            +  ++     FV Y                     +T+ +I    DS    S   VL  
Sbjct: 128 DNQIYIAGHPAFVNY---------------------STSQKISRPGDSDDSRSVNSVLLF 166

Query: 473 VVDNWNHEKITNLHLFKIFQHYGILERIVIYVSKGVVQGFIQYSDPFSAKVAKALTNELC 652
            + N  +   T++ L+ I    G ++RIVI+   G VQ  +++    SA+ AKA  N   
Sbjct: 167 TILNPIYSITTDV-LYTICNPCGPVQRIVIFRKNG-VQAMVEFDSVQSAQRAKASLNGAD 224

Query: 653 IFPRSCIMRVNFSNRQSLDISREDDLVRDFVRHPVSPQ 766
           I+   C +++ ++    L++ + D    D+    +S Q
Sbjct: 225 IYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQ 262


 Score = 36.6 bits (83), Expect = 0.24
 Identities = 28/109 (25%), Positives = 49/109 (44%), Gaps = 11/109 (10%)
 Frame = +2

Query: 986  DFSRNDRNDAYGRTHFGEKTSPLLIVSNLNEA-KIHPDALFKLFGCYGDVTRVKIMYNRK 1162
            ++S + +    G +      + +L+ + LN    I  D L+ +    G V R+ I     
Sbjct: 141  NYSTSQKISRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNG 200

Query: 1163 NTALVQFANEEFAQRALQYLNGVNL----------YGKPLHVNFSKHDR 1279
              A+V+F + + AQRA   LNG ++          Y KP  +N  K+D+
Sbjct: 201  VQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQ 249

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 195,125,817
Number of Sequences: 369166
Number of extensions: 3914569
Number of successful extensions: 10204
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 9492
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10178
length of database: 68,354,980
effective HSP length: 116
effective length of database: 46,925,720
effective search space used: 22524345600
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00027

  1. Dr_sW_001_K22
  2. Dr_sW_023_B16
  3. Dr_sW_025_N12
  4. Dr_sW_003_M19