Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_N12
(622 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein ... 86 6e-17
sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 ... 82 8e-16
sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 ... 81 2e-15
sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1) 80 4e-15
sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1) 80 4e-15
sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1) 79 7e-15
sp|Q921F4|HNRLL_MOUSE Heterogeneous nuclear ribonucleoprote... 61 3e-09
sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprote... 61 3e-09
sp|P17225|PTBP1_MOUSE Polypyrimidine tract-binding protein ... 61 3e-09
sp|P14866|HNRPL_HUMAN Heterogeneous nuclear ribonucleoprote... 59 1e-08
>sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I) (57 kDa RNA-binding
protein PPTB-1)
Length = 531
Score = 86.3 bits (212), Expect = 6e-17
Identities = 40/77 (51%), Positives = 55/77 (71%)
Frame = +2
Query: 371 LLIVSNLNEAKIHPDALFKLFGCYGDVTRVKIMYNRKNTALVQFANEEFAQRALQYLNGV 550
+L+VSNLN ++ P +LF LFG YGDV RVKI++N+K ALVQ A+ AQ A+ +LNG
Sbjct: 338 VLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGNQAQLAMSHLNGH 397
Query: 551 YLYGKPLHVNFSKHDRI 601
L+GKP+ + SKH +
Sbjct: 398 KLHGKPIRITLSKHQNV 414
Score = 33.9 bits (76), Expect = 0.34
Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Frame = +2
Query: 440 YGDVTRVKIMYNRKNTALVQFANEEFAQRALQYLNGV--YLYGKPLHVNFSKHDRI 601
+G VT + +M KN A ++ EE A + Y V L G+P+++ FS H +
Sbjct: 82 FGKVTNL-LMLKGKNQAFIEMNTEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKEL 136
>sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I)
Length = 557
Score = 82.4 bits (202), Expect = 8e-16
Identities = 39/77 (50%), Positives = 54/77 (70%)
Frame = +2
Query: 371 LLIVSNLNEAKIHPDALFKLFGCYGDVTRVKIMYNRKNTALVQFANEEFAQRALQYLNGV 550
+L+VSNLN ++ P +LF LFG Y DV RVKI++N+K ALVQ A+ AQ A+ +LNG
Sbjct: 364 VLLVSNLNPERVTPQSLFILFGVYCDVQRVKILFNKKENALVQMADGSQAQLAMSHLNGH 423
Query: 551 YLYGKPLHVNFSKHDRI 601
L+GKP+ + SKH +
Sbjct: 424 KLHGKPVRITLSKHQNV 440
Score = 33.9 bits (76), Expect = 0.34
Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Frame = +2
Query: 440 YGDVTRVKIMYNRKNTALVQFANEEFAQRALQYLNGV--YLYGKPLHVNFSKHDRI 601
+G VT + +M KN A ++ EE A + Y V L G+P+++ FS H +
Sbjct: 82 FGKVTNL-LMLKGKNQAFIEMNTEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKEL 136
>sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I) (Pyrimidine-binding
protein) (PYBP)
Length = 555
Score = 81.3 bits (199), Expect = 2e-15
Identities = 38/77 (49%), Positives = 54/77 (70%)
Frame = +2
Query: 371 LLIVSNLNEAKIHPDALFKLFGCYGDVTRVKIMYNRKNTALVQFANEEFAQRALQYLNGV 550
+L+VSNLN ++ P +LF LFG YGDV RVKI++N+K ALV+ A+ AQ A+ +LNG
Sbjct: 362 VLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVEMADGSQAQLAMSHLNGH 421
Query: 551 YLYGKPLHVNFSKHDRI 601
L+GK + + SKH +
Sbjct: 422 KLHGKSVRITLSKHQSV 438
Score = 35.0 bits (79), Expect = 0.15
Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
Frame = +2
Query: 440 YGDVTRVKIMYNRKNTALVQFANEEFAQRALQYLNGV--YLYGKPLHVNFSKHDRI 601
+G VT + +M KN A ++ + EE A + Y V L G+P+++ FS H +
Sbjct: 81 FGKVTNL-LMLKGKNQAFIEMSTEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKEL 135
>sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1)
Length = 523
Score = 80.1 bits (196), Expect = 4e-15
Identities = 42/83 (50%), Positives = 53/83 (63%)
Frame = +2
Query: 353 GEKTSPLLIVSNLNEAKIHPDALFKLFGCYGDVTRVKIMYNRKNTALVQFANEEFAQRAL 532
G + +L+V+NLN I P LF LFG YGDV RVKIM+N+K ALVQ A+ AQ A+
Sbjct: 324 GMPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQLAM 383
Query: 533 QYLNGVYLYGKPLHVNFSKHDRI 601
+L+G LYGK L SKH +
Sbjct: 384 NHLSGQRLYGKVLRATLSKHQAV 406
>sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1)
Length = 521
Score = 80.1 bits (196), Expect = 4e-15
Identities = 41/77 (53%), Positives = 51/77 (66%)
Frame = +2
Query: 371 LLIVSNLNEAKIHPDALFKLFGCYGDVTRVKIMYNRKNTALVQFANEEFAQRALQYLNGV 550
+L+V+NLN I P LF LFG YGDV RVKIM+N+K ALVQ A+ AQ A+ +L+G
Sbjct: 328 VLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQ 387
Query: 551 YLYGKPLHVNFSKHDRI 601
LYGK L SKH +
Sbjct: 388 RLYGKVLRATLSKHQAV 404
>sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1)
Length = 523
Score = 79.3 bits (194), Expect = 7e-15
Identities = 41/77 (53%), Positives = 51/77 (66%)
Frame = +2
Query: 371 LLIVSNLNEAKIHPDALFKLFGCYGDVTRVKIMYNRKNTALVQFANEEFAQRALQYLNGV 550
+L+V+NLN I P LF LFG YGDV RVKIM+N+K ALVQ A+ AQ A+ +L+G
Sbjct: 330 VLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQIAMNHLSGQ 389
Query: 551 YLYGKPLHVNFSKHDRI 601
LYGK L SKH +
Sbjct: 390 RLYGKVLRATLSKHQAV 406
>sp|Q921F4|HNRLL_MOUSE Heterogeneous nuclear ribonucleoprotein L-like
Length = 591
Score = 60.8 bits (146), Expect = 3e-09
Identities = 31/85 (36%), Positives = 51/85 (60%)
Frame = +2
Query: 347 HFGEKTSPLLIVSNLNEAKIHPDALFKLFGCYGDVTRVKIMYNRKNTALVQFANEEFAQR 526
H G + +++VS L++ K++ +F LF YG++ +VK M TALV+ +E +R
Sbjct: 377 HGGSPSGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVER 436
Query: 527 ALQYLNGVYLYGKPLHVNFSKHDRI 601
A+ +LN V L+GK L+V SK +
Sbjct: 437 AVTHLNNVKLFGKRLNVCVSKQHSV 461
Score = 29.3 bits (64), Expect = 8.4
Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 3/103 (2%)
Frame = +2
Query: 305 DFSRNDRNDAYGRTHFGEKTSPLLIVSNLNEA-KIHPDALFKLFGCYGDVTRVKIMYNRK 481
++S + R G T + +L++S N I D L+ + G V R+ I
Sbjct: 195 NYSTSKRITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGKVQRIVIFKRNG 254
Query: 482 NTALVQFANEEFAQRALQYLNGVYLYGK--PLHVNFSKHDRIS 604
A+V+F + AQ+A LNG +Y L + +++ R++
Sbjct: 255 IQAMVEFESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLN 297
>sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprotein L-like (Stromal
RNA-regulating factor) (BLOCK24 protein)
Length = 542
Score = 60.8 bits (146), Expect = 3e-09
Identities = 31/85 (36%), Positives = 51/85 (60%)
Frame = +2
Query: 347 HFGEKTSPLLIVSNLNEAKIHPDALFKLFGCYGDVTRVKIMYNRKNTALVQFANEEFAQR 526
H G + +++VS L++ K++ +F LF YG++ +VK M TALV+ +E +R
Sbjct: 328 HGGNPSGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVER 387
Query: 527 ALQYLNGVYLYGKPLHVNFSKHDRI 601
A+ +LN V L+GK L+V SK +
Sbjct: 388 AVTHLNNVKLFGKRLNVCVSKQHSV 412
Score = 29.3 bits (64), Expect = 8.4
Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 3/103 (2%)
Frame = +2
Query: 305 DFSRNDRNDAYGRTHFGEKTSPLLIVSNLNEA-KIHPDALFKLFGCYGDVTRVKIMYNRK 481
++S + R G T + +L++S N I D L+ + G V R+ I
Sbjct: 146 NYSTSKRITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGKVQRIVIFKRNG 205
Query: 482 NTALVQFANEEFAQRALQYLNGVYLYGK--PLHVNFSKHDRIS 604
A+V+F + AQ+A LNG +Y L + +++ R++
Sbjct: 206 IQAMVEFESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLN 248
>sp|P17225|PTBP1_MOUSE Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I)
Length = 527
Score = 60.8 bits (146), Expect = 3e-09
Identities = 29/51 (56%), Positives = 38/51 (74%)
Frame = +2
Query: 371 LLIVSNLNEAKIHPDALFKLFGCYGDVTRVKIMYNRKNTALVQFANEEFAQ 523
+L+VSNLN ++ P +LF LFG YGDV RVKI++N+K ALVQ A+ AQ
Sbjct: 336 VLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQ 386
Score = 33.9 bits (76), Expect = 0.34
Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Frame = +2
Query: 440 YGDVTRVKIMYNRKNTALVQFANEEFAQRALQYLNGV--YLYGKPLHVNFSKHDRI 601
+G VT + +M KN A ++ EE A + Y V L G+P+++ FS H +
Sbjct: 81 FGKVTNL-LMLKGKNQAFIEMNTEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKEL 135
>sp|P14866|HNRPL_HUMAN Heterogeneous nuclear ribonucleoprotein L (hnRNP L)
Length = 558
Score = 58.5 bits (140), Expect = 1e-08
Identities = 28/79 (35%), Positives = 51/79 (64%)
Frame = +2
Query: 365 SPLLIVSNLNEAKIHPDALFKLFGCYGDVTRVKIMYNRKNTALVQFANEEFAQRALQYLN 544
SP+L+V L+++K++ D +F +F YG+V +VK M ++ A+V+ A+ RA+ +LN
Sbjct: 350 SPVLMVYGLDQSKMNGDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLN 409
Query: 545 GVYLYGKPLHVNFSKHDRI 601
+++G+ L+V SK I
Sbjct: 410 NNFMFGQKLNVCVSKQPAI 428
Score = 35.0 bits (79), Expect = 0.15
Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 11/109 (10%)
Frame = +2
Query: 305 DFSRNDRNDAYGRTHFGEKTSPLLIVSNLNEA-KIHPDALFKLFGCYGDVTRVKIMYNRK 481
++S + + G + + +L+ + LN I D L+ + G V R+ I
Sbjct: 141 NYSTSQKISRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNG 200
Query: 482 NTALVQFANEEFAQRALQYLNGVYL----------YGKPLHVNFSKHDR 598
A+V+F + + AQRA LNG + Y KP +N K+D+
Sbjct: 201 VQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQ 249
Score = 34.7 bits (78), Expect = 0.20
Identities = 25/82 (30%), Positives = 43/82 (52%), Gaps = 2/82 (2%)
Frame = +2
Query: 365 SPLLIVSNLNEAKIHPDALFKLFGCYGDVTRVKIMYNRKNTALVQFANEEFAQRALQYL- 541
SP++ + L + + D L + +G ++ V +M +K ALV+F + A A+ Y
Sbjct: 70 SPVVHIRGLIDGVVEAD-LVEALQEFGPISYVVVM-PKKRQALVEFEDVLGACNAVNYAA 127
Query: 542 -NGVYLYGKPLHVNFSKHDRIS 604
N +Y+ G P VN+S +IS
Sbjct: 128 DNQIYIAGHPAFVNYSTSQKIS 149
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,328,423
Number of Sequences: 369166
Number of extensions: 1340665
Number of successful extensions: 3783
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3609
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3779
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 4877307000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)