Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_B16
(736 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1) 115 1e-25
sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 ... 115 1e-25
sp|P17225|PTBP1_MOUSE Polypyrimidine tract-binding protein ... 115 2e-25
sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1) 114 3e-25
sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 ... 114 3e-25
sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1) 113 5e-25
sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein ... 113 6e-25
sp|Q8R081|HNRPL_MOUSE Heterogeneous nuclear ribonucleoprote... 62 2e-09
sp|P14866|HNRPL_HUMAN Heterogeneous nuclear ribonucleoprote... 62 2e-09
sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprote... 59 1e-08
>sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1)
Length = 521
Score = 115 bits (288), Expect = 1e-25
Identities = 66/218 (30%), Positives = 110/218 (50%), Gaps = 12/218 (5%)
Frame = +3
Query: 3 QVLHIRSLPDDVTELEIASVATPFGHISYMVLTRKTGQALLEMETKDIAETMFEYYQRHA 182
+VLH+R +P DVTE EI S+ PFG ++ +++ + QA LEM +++ A TM YY
Sbjct: 28 RVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYYTPIT 87
Query: 183 PHLRNKRCFVQYXXXXXXXXXXXXXXPEAENAVTTANQICDSMAKESSG----------- 329
PHLR++ ++QY A+ A+ + + S G
Sbjct: 88 PHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTVLPGQ 147
Query: 330 -PVLRLVVDNWNHEKITNLHLFKIFQHYGILERIVIYVSKGVVQGFIQYSDPFSAKVAKA 506
PVLR++++N + +T L +IF +G + +I+ + Q +QY+DP +A AK
Sbjct: 148 SPVLRIIIENLFY-PVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYAKM 206
Query: 507 LTNELCIFPRSCIMRVNFSNRQSLDISREDDLVRDFVR 620
+ I+ C +R++FS SL++ +D RDF R
Sbjct: 207 ALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTR 244
>sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I) (Pyrimidine-binding
protein) (PYBP)
Length = 555
Score = 115 bits (288), Expect = 1e-25
Identities = 66/220 (30%), Positives = 110/220 (50%), Gaps = 14/220 (6%)
Frame = +3
Query: 3 QVLHIRSLPDDVTELEIASVATPFGHISYMVLTRKTGQALLEMETKDIAETMFEYYQRHA 182
+V+H+R LP DVTE E+ S+ PFG ++ +++ + QA +EM T++ A TM YY A
Sbjct: 58 RVIHVRKLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMSTEEAANTMVNYYTSVA 117
Query: 183 PHLRNKRCFVQYXXXXXXXXXXXXXXPEAENAVTTANQICD--------------SMAKE 320
P LR + ++Q+ A+ A+ N + MA
Sbjct: 118 PVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASAAAVDAGMAMA 177
Query: 321 SSGPVLRLVVDNWNHEKITNLHLFKIFQHYGILERIVIYVSKGVVQGFIQYSDPFSAKVA 500
PVLR++V+N + +T L +IF +G + +I+ + Q +QY+DP SA+ A
Sbjct: 178 GQSPVLRIIVENLFY-PVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHA 236
Query: 501 KALTNELCIFPRSCIMRVNFSNRQSLDISREDDLVRDFVR 620
K + I+ C +R++FS SL++ +D RD+ R
Sbjct: 237 KLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTR 276
>sp|P17225|PTBP1_MOUSE Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I)
Length = 527
Score = 115 bits (287), Expect = 2e-25
Identities = 66/220 (30%), Positives = 110/220 (50%), Gaps = 14/220 (6%)
Frame = +3
Query: 3 QVLHIRSLPDDVTELEIASVATPFGHISYMVLTRKTGQALLEMETKDIAETMFEYYQRHA 182
+V+H+R LP DVTE E+ S+ PFG ++ +++ + QA +EM T++ A TM YY A
Sbjct: 58 RVIHVRKLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVA 117
Query: 183 PHLRNKRCFVQYXXXXXXXXXXXXXXPEAENAVTTANQICD--------------SMAKE 320
P LR + ++Q+ A+ A+ N + MA
Sbjct: 118 PVLRGQPIYIQFSNHKELKTDSSPNQVRAQAALQAVNSVQSGNLALAASAAAVDAGMAMA 177
Query: 321 SSGPVLRLVVDNWNHEKITNLHLFKIFQHYGILERIVIYVSKGVVQGFIQYSDPFSAKVA 500
PVLR++V+N + +T L +IF +G + +I+ + Q +QY+DP SA+ A
Sbjct: 178 GQSPVLRIIVENLFY-PVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHA 236
Query: 501 KALTNELCIFPRSCIMRVNFSNRQSLDISREDDLVRDFVR 620
K + I+ C +R++FS SL++ +D RD+ R
Sbjct: 237 KLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTR 276
>sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1)
Length = 523
Score = 114 bits (285), Expect = 3e-25
Identities = 67/218 (30%), Positives = 115/218 (52%), Gaps = 12/218 (5%)
Frame = +3
Query: 3 QVLHIRSLPDDVTELEIASVATPFGHISYMVLTRKTGQALLEMETKDIAETMFEYYQRHA 182
+VLH+R +P DVTE E+ S+ PFG ++ +++ + QA LEM +++ A TM YY
Sbjct: 30 RVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMINYYTPVT 89
Query: 183 PHLRNKRCFVQYXXXXXXXXXXXXXXPEAE------NAVTTAN-QICDSMAKESS----- 326
PHLR++ ++QY A+ +AV + N + + A E +
Sbjct: 90 PHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGATANEGTLLPGQ 149
Query: 327 GPVLRLVVDNWNHEKITNLHLFKIFQHYGILERIVIYVSKGVVQGFIQYSDPFSAKVAKA 506
PVLR++++N + +T L +IF +G + +I+ + Q +QY+DP +A+ AK
Sbjct: 150 SPVLRIIIENLFY-PVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAQYAKM 208
Query: 507 LTNELCIFPRSCIMRVNFSNRQSLDISREDDLVRDFVR 620
+ I+ C +R++FS SL++ +D RDF R
Sbjct: 209 ALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTR 246
>sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I)
Length = 557
Score = 114 bits (285), Expect = 3e-25
Identities = 66/220 (30%), Positives = 109/220 (49%), Gaps = 14/220 (6%)
Frame = +3
Query: 3 QVLHIRSLPDDVTELEIASVATPFGHISYMVLTRKTGQALLEMETKDIAETMFEYYQRHA 182
+V+HIR LP DVTE E+ S+ PFG ++ +++ + QA +EM T++ A TM YY
Sbjct: 59 RVIHIRKLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVT 118
Query: 183 PHLRNKRCFVQYXXXXXXXXXXXXXXPEAENAVTTANQICD--------------SMAKE 320
P LR + ++Q+ A+ A+ N + MA
Sbjct: 119 PVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASAAAVDAGMAMA 178
Query: 321 SSGPVLRLVVDNWNHEKITNLHLFKIFQHYGILERIVIYVSKGVVQGFIQYSDPFSAKVA 500
PVLR++V+N + +T L +IF +G + +I+ + Q +QY+DP SA+ A
Sbjct: 179 GQSPVLRIIVENLFY-PVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHA 237
Query: 501 KALTNELCIFPRSCIMRVNFSNRQSLDISREDDLVRDFVR 620
K + I+ C +R++FS SL++ +D RD+ R
Sbjct: 238 KLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTR 277
>sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1)
Length = 523
Score = 113 bits (283), Expect = 5e-25
Identities = 63/218 (28%), Positives = 110/218 (50%), Gaps = 12/218 (5%)
Frame = +3
Query: 3 QVLHIRSLPDDVTELEIASVATPFGHISYMVLTRKTGQALLEMETKDIAETMFEYYQRHA 182
+VLH+R +P DVTE E+ S+ PFG ++ +++ + QA LEM +++ A TM YY
Sbjct: 30 RVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMINYYTPVT 89
Query: 183 PHLRNKRCFVQYXXXXXXXXXXXXXXPEAENAVTTANQI------------CDSMAKESS 326
PHLR++ ++QY A+ A+ + + +
Sbjct: 90 PHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGATSNEGTLLPGQ 149
Query: 327 GPVLRLVVDNWNHEKITNLHLFKIFQHYGILERIVIYVSKGVVQGFIQYSDPFSAKVAKA 506
PVLR++++N + +T L +IF +G + +I+ + Q +QY+DP +A+ AK
Sbjct: 150 SPVLRIIIENLFY-PVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAQYAKM 208
Query: 507 LTNELCIFPRSCIMRVNFSNRQSLDISREDDLVRDFVR 620
+ I+ C +R++FS SL++ +D RDF R
Sbjct: 209 ALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTR 246
>sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I) (57 kDa RNA-binding
protein PPTB-1)
Length = 531
Score = 113 bits (282), Expect = 6e-25
Identities = 66/220 (30%), Positives = 109/220 (49%), Gaps = 14/220 (6%)
Frame = +3
Query: 3 QVLHIRSLPDDVTELEIASVATPFGHISYMVLTRKTGQALLEMETKDIAETMFEYYQRHA 182
+V+HIR LP DVTE E+ S+ PFG ++ +++ + QA +EM T++ A TM YY
Sbjct: 59 RVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVT 118
Query: 183 PHLRNKRCFVQYXXXXXXXXXXXXXXPEAENAVTTANQICD--------------SMAKE 320
P LR + ++Q+ A+ A+ N + MA
Sbjct: 119 PVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASAAAVDAGMAMA 178
Query: 321 SSGPVLRLVVDNWNHEKITNLHLFKIFQHYGILERIVIYVSKGVVQGFIQYSDPFSAKVA 500
PVLR++V+N + +T L +IF +G + +I+ + Q +QY+DP SA+ A
Sbjct: 179 GQSPVLRIIVENLFY-PVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHA 237
Query: 501 KALTNELCIFPRSCIMRVNFSNRQSLDISREDDLVRDFVR 620
K + I+ C +R++FS SL++ +D RD+ R
Sbjct: 238 KLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTR 277
>sp|Q8R081|HNRPL_MOUSE Heterogeneous nuclear ribonucleoprotein L (hnRNP L)
Length = 555
Score = 62.0 bits (149), Expect = 2e-09
Identities = 57/214 (26%), Positives = 92/214 (42%), Gaps = 3/214 (1%)
Frame = +3
Query: 6 VLHIRSLPDDVTELEIASVATPFGHISYMVLTRKTGQALLEMETKDIAETMFEYYQRHAP 185
V+HIR L D V E ++ FG ISY+V+ K QAL+E E A Y +
Sbjct: 69 VVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQI 128
Query: 186 HLRNKRCFVQYXXXXXXXXXXXXXXPEAENAVTTANQIC---DSMAKESSGPVLRLVVDN 356
++ FV Y +T+ +I DS S VL + N
Sbjct: 129 YIAGHPAFVNY---------------------STSQKISRPGDSDDSRSVNSVLLFTILN 167
Query: 357 WNHEKITNLHLFKIFQHYGILERIVIYVSKGVVQGFIQYSDPFSAKVAKALTNELCIFPR 536
+ T++ L+ I G ++RIVI+ G VQ +++ SA+ AKA N I+
Sbjct: 168 PIYSITTDV-LYTICNPCGPVQRIVIFRKNG-VQAMVEFDSVQSAQRAKASLNGADIYSG 225
Query: 537 SCIMRVNFSNRQSLDISREDDLVRDFVRHPVSPQ 638
C +++ ++ L++ + D D+ +S Q
Sbjct: 226 CCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQ 259
>sp|P14866|HNRPL_HUMAN Heterogeneous nuclear ribonucleoprotein L (hnRNP L)
Length = 558
Score = 62.0 bits (149), Expect = 2e-09
Identities = 57/214 (26%), Positives = 92/214 (42%), Gaps = 3/214 (1%)
Frame = +3
Query: 6 VLHIRSLPDDVTELEIASVATPFGHISYMVLTRKTGQALLEMETKDIAETMFEYYQRHAP 185
V+HIR L D V E ++ FG ISY+V+ K QAL+E E A Y +
Sbjct: 72 VVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQI 131
Query: 186 HLRNKRCFVQYXXXXXXXXXXXXXXPEAENAVTTANQIC---DSMAKESSGPVLRLVVDN 356
++ FV Y +T+ +I DS S VL + N
Sbjct: 132 YIAGHPAFVNY---------------------STSQKISRPGDSDDSRSVNSVLLFTILN 170
Query: 357 WNHEKITNLHLFKIFQHYGILERIVIYVSKGVVQGFIQYSDPFSAKVAKALTNELCIFPR 536
+ T++ L+ I G ++RIVI+ G VQ +++ SA+ AKA N I+
Sbjct: 171 PIYSITTDV-LYTICNPCGPVQRIVIFRKNG-VQAMVEFDSVQSAQRAKASLNGADIYSG 228
Query: 537 SCIMRVNFSNRQSLDISREDDLVRDFVRHPVSPQ 638
C +++ ++ L++ + D D+ +S Q
Sbjct: 229 CCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQ 262
>sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprotein L-like (Stromal
RNA-regulating factor) (BLOCK24 protein)
Length = 542
Score = 59.3 bits (142), Expect = 1e-08
Identities = 44/205 (21%), Positives = 83/205 (40%)
Frame = +3
Query: 6 VLHIRSLPDDVTELEIASVATPFGHISYMVLTRKTGQALLEMETKDIAETMFEYYQRHAP 185
V+H+R L + V E ++ FG I Y+++ QAL+E E D A+ +
Sbjct: 77 VVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFENIDSAKECVTFAADEPV 136
Query: 186 HLRNKRCFVQYXXXXXXXXXXXXXXPEAENAVTTANQICDSMAKESSGPVLRLVVDNWNH 365
++ ++ F Y P N V + P+ + VD
Sbjct: 137 YIAGQQAFFNYSTSKRITRPGNTDDPSGGNKV---------LLLSIQNPLYPITVD---- 183
Query: 366 EKITNLHLFKIFQHYGILERIVIYVSKGVVQGFIQYSDPFSAKVAKALTNELCIFPRSCI 545
L+ + G ++RIVI+ G +Q +++ A+ AKA N I+ C
Sbjct: 184 ------VLYTVCNPVGKVQRIVIFKRNG-IQAMVEFESVLCAQKAKAALNGADIYAGCCT 236
Query: 546 MRVNFSNRQSLDISREDDLVRDFVR 620
+++ ++ L++ R D+ D+ +
Sbjct: 237 LKIEYARPTRLNVIRNDNDSWDYTK 261
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,152,504
Number of Sequences: 369166
Number of extensions: 1374386
Number of successful extensions: 3390
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3315
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3379
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6582889600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)