DrC_01116
- Cluster detail
- GO Category : Not Available
- Consensus Sequence :
BLASTX 2.2.13 [Nov-27-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01116 (846 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q8WMQ3|CD9_PIG CD9 antigen 82 2e-15 sp|Q922J6|TSN2_MOUSE Tetraspanin-2 (Tspan-2) 78 3e-14 sp|Q9JJW1|TSN2_RAT Tetraspanin-2 (Tspan-2) 77 5e-14 sp|O60636|TSN2_HUMAN Tetraspanin-2 (Tspan-2) 76 1e-13 sp|P40239|CD9_FELCA CD9 antigen 75 2e-13 sp|P30409|CD9_CERAE CD9 antigen (27 kDa diphtheria toxin re... 75 3e-13 sp|P21926|CD9_HUMAN CD9 antigen (p24) (Leukocyte antigen MI... 75 3e-13 sp|P30932|CD9_BOVIN CD9 antigen 74 7e-13 sp|P40240|CD9_MOUSE CD9 antigen 73 9e-13 sp|O97703|CD81_CERAE CD81 antigen 72 1e-12
>sp|Q8WMQ3|CD9_PIG CD9 antigen Length = 226 Score = 81.6 bits (200), Expect = 2e-15 Identities = 59/220 (26%), Positives = 89/220 (40%), Gaps = 8/220 (3%) Frame = +3 Query: 129 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNMGA---DGSAVVIAFYVTMGVGAFT 299 CI+ L+ FNFIF L K++ + S+ Y+ +G GA Sbjct: 9 CIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQENNNSSFYTGVYILIGAGALM 68 Query: 300 LIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKGKN 479 ++VG GCCGA ES C+LG + + + +KD V V++ + N Sbjct: 69 MVVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDQVIKEVQDFYRDTYN 128 Query: 480 EISGDNKNNNGHWMHEAHKYLQCCGNKGPSDYSSPPKSCCLADNCENVN-----SMKGCG 644 ++ G + + + H L CCG G + LAD C + MK C Sbjct: 129 KLKGKD-DPQRETLKAIHYALDCCGLMGEVEQ-------LLADICPQRDVLSSLPMKPCP 180 Query: 645 ETWKELIQNRWILFASVXXXXXXXXXXXXXFSMCLCCTAR 764 E KE+ QN++ + +V FSM LCC R Sbjct: 181 EAIKEVFQNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIR 220
>sp|Q922J6|TSN2_MOUSE Tetraspanin-2 (Tspan-2) Length = 221 Score = 78.2 bits (191), Expect = 3e-14 Identities = 56/216 (25%), Positives = 89/216 (41%), Gaps = 3/216 (1%) Frame = +3 Query: 129 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNMGADGSA---VVIAFYVTMGVGAFT 299 CI+ L++ FN +F L K++ ++ + + YV +G GA Sbjct: 10 CIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGTMKDLSSEDKSPEYFYVGLYVLVGAGALM 69 Query: 300 LIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKGKN 479 + VG GCCGA ES C+LG++ GV F+ KD +V++ +E+ + Sbjct: 70 MTVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKDVAIRHVQSMYEEAYS 129 Query: 480 EISGDNKNNNGHWMHEAHKYLQCCGNKGPSDYSSPPKSCCLADNCENVNSMKGCGETWKE 659 + D NG + H QCCG K S+ P +C + + K C + + Sbjct: 130 DYLKDRARGNG-TLITFHSAFQCCG-KESSEQVQP--TC-----PKELPGHKNCIDKIET 180 Query: 660 LIQNRWILFASVXXXXXXXXXXXXXFSMCLCCTARS 767 +I + L V FSM LCC R+ Sbjct: 181 VISAKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRN 216
>sp|Q9JJW1|TSN2_RAT Tetraspanin-2 (Tspan-2) Length = 221 Score = 77.4 bits (189), Expect = 5e-14 Identities = 56/216 (25%), Positives = 89/216 (41%), Gaps = 3/216 (1%) Frame = +3 Query: 129 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNMGADGSA---VVIAFYVTMGVGAFT 299 CI+ L++ FN +F L K++ ++ + + YV +G GA Sbjct: 10 CIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGTIKDLSSEEKSPEYFYVGLYVLVGAGALM 69 Query: 300 LIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKGKN 479 + VG GCCGA ES C+LG++ GV F+ KD +V++ +E+ + Sbjct: 70 MAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKDVAIRHVQSMYEEAYS 129 Query: 480 EISGDNKNNNGHWMHEAHKYLQCCGNKGPSDYSSPPKSCCLADNCENVNSMKGCGETWKE 659 + D NG + H QCCG K S+ P +C + + K C + + Sbjct: 130 DYVRDRGRGNG-TLITFHSAFQCCG-KESSEQVQP--TC-----PKELPGHKNCIDKIET 180 Query: 660 LIQNRWILFASVXXXXXXXXXXXXXFSMCLCCTARS 767 +I + L V FSM LCC R+ Sbjct: 181 IISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRN 216
>sp|O60636|TSN2_HUMAN Tetraspanin-2 (Tspan-2) Length = 221 Score = 75.9 bits (185), Expect = 1e-13 Identities = 56/216 (25%), Positives = 86/216 (39%), Gaps = 3/216 (1%) Frame = +3 Query: 129 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNMGADGSA---VVIAFYVTMGVGAFT 299 CI+ L++ FN +F L K + ++ + + YV +G GA Sbjct: 10 CIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLYVLVGAGALM 69 Query: 300 LIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKGKN 479 + VG GCCGA ES C+LG++ GV F+ K +V+ +E+ N Sbjct: 70 MAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAYN 129 Query: 480 EISGDNKNNNGHWMHEAHKYLQCCGNKGPSDYSSPPKSCCLADNCENVNSMKGCGETWKE 659 + D NG + H QCCG K S+ P +C + + K C + + Sbjct: 130 DYLKDRGKGNG-TLITFHSTFQCCG-KESSEQVQP--TC-----PKELLGHKNCIDEIET 180 Query: 660 LIQNRWILFASVXXXXXXXXXXXXXFSMCLCCTARS 767 +I + L V FSM LCC R+ Sbjct: 181 IISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRN 216
>sp|P40239|CD9_FELCA CD9 antigen Length = 226 Score = 75.5 bits (184), Expect = 2e-13 Identities = 53/215 (24%), Positives = 86/215 (40%), Gaps = 3/215 (1%) Frame = +3 Query: 129 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNM---GADGSAVVIAFYVTMGVGAFT 299 CI+ L+ FNFIF L K++ + S+ Y+ +G GA Sbjct: 9 CIKYLLFGFNFIFWLAGIAVLAVGLWLRFDSQTKSIFEQDSQPSSFYTGVYILIGAGALM 68 Query: 300 LIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKGKN 479 ++VG GCCGA ES C+LG + + + +KD V V+ ++ N Sbjct: 69 MLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDEVIQEVQEFYKDTYN 128 Query: 480 EISGDNKNNNGHWMHEAHKYLQCCGNKGPSDYSSPPKSCCLADNCENVNSMKGCGETWKE 659 ++ ++ + H L CCG G + C + + ++K C E KE Sbjct: 129 KLKSKDEPQR-DTLKAIHYALDCCGLAGGVEQFI--SDICPQKDILSSITVKPCPEAIKE 185 Query: 660 LIQNRWILFASVXXXXXXXXXXXXXFSMCLCCTAR 764 + N++ + +V FSM LCC R Sbjct: 186 VFHNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIR 220
>sp|P30409|CD9_CERAE CD9 antigen (27 kDa diphtheria toxin receptor-associated protein) (DRAP27) Length = 228 Score = 74.7 bits (182), Expect = 3e-13 Identities = 52/217 (23%), Positives = 85/217 (39%), Gaps = 5/217 (2%) Frame = +3 Query: 129 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNM-----GADGSAVVIAFYVTMGVGA 293 CI+ L+ FNFIF L K++ + S+ Y+ +G GA Sbjct: 9 CIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQETNNNNSSFYTGVYILIGAGA 68 Query: 294 FTLIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKG 473 ++VG GCCGA ES C+LG + + + +KD V V+ ++ Sbjct: 69 LMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDEVIKEVQEFYKDT 128 Query: 474 KNEISGDNKNNNGHWMHEAHKYLQCCGNKGPSDYSSPPKSCCLADNCENVNSMKGCGETW 653 N++ ++ + H L CCG G + C + ++K C + Sbjct: 129 YNKLKTKDEPQR-ETLKAIHYALDCCGLAGGVEQFI--SDICPKKDVLETFTIKSCPDAI 185 Query: 654 KELIQNRWILFASVXXXXXXXXXXXXXFSMCLCCTAR 764 KE+ N++ + +V FSM LCC R Sbjct: 186 KEVFDNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIR 222
>sp|P21926|CD9_HUMAN CD9 antigen (p24) (Leukocyte antigen MIC3) (Motility-related protein) (MRP-1) (Tetraspanin-29) (Tspan-29) Length = 228 Score = 74.7 bits (182), Expect = 3e-13 Identities = 52/217 (23%), Positives = 85/217 (39%), Gaps = 5/217 (2%) Frame = +3 Query: 129 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNM-----GADGSAVVIAFYVTMGVGA 293 CI+ L+ FNFIF L K++ + S+ Y+ +G GA Sbjct: 9 CIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQETNNNNSSFYTGVYILIGAGA 68 Query: 294 FTLIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKG 473 ++VG GCCGA ES C+LG + + + +KD V V+ ++ Sbjct: 69 LMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDEVIKEVQEFYKDT 128 Query: 474 KNEISGDNKNNNGHWMHEAHKYLQCCGNKGPSDYSSPPKSCCLADNCENVNSMKGCGETW 653 N++ ++ + H L CCG G + C + ++K C + Sbjct: 129 YNKLKTKDEPQR-ETLKAIHYALNCCGLAGGVEQFI--SDICPKKDVLETFTVKSCPDAI 185 Query: 654 KELIQNRWILFASVXXXXXXXXXXXXXFSMCLCCTAR 764 KE+ N++ + +V FSM LCC R Sbjct: 186 KEVFDNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIR 222
>sp|P30932|CD9_BOVIN CD9 antigen Length = 226 Score = 73.6 bits (179), Expect = 7e-13 Identities = 58/226 (25%), Positives = 95/226 (42%), Gaps = 7/226 (3%) Frame = +3 Query: 129 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNMGA---DGSAVVIAFYVTMGVGAFT 299 CI+ L+ FNFIF L K++ + S+ Y+ +G GA Sbjct: 9 CIKYLLFGFNFIFWLAGIAVLSVGLWLRFDSQTKSIFEQENNDSSFYTGVYILIGAGALM 68 Query: 300 LIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKGKN 479 ++VG GCCGA ES C+LG + + + +K+ V V+ +E N Sbjct: 69 MLVGFLGCCGAVQESQCMLGLFFSFLLVIFAIEVAAAIWGYSHKEEVIKEVQKFYEDTYN 128 Query: 480 EISGDNKNNNGHWMHEAHKYLQCCGNKG-PSDY---SSPPKSCCLADNCENVNSMKGCGE 647 ++ ++ + H L CCG G P + + PPK+ L D+ + + C E Sbjct: 129 KLKNKDEPQR-ETLKAIHIALDCCGLTGVPEQFLTDTCPPKN--LIDSLKT----RPCPE 181 Query: 648 TWKELIQNRWILFASVXXXXXXXXXXXXXFSMCLCCTARSIDYDMV 785 E+ ++++ + +V FSM LCC R + DMV Sbjct: 182 AIDEIFRSKFHIIGAVGIGIAVVMIFGMVFSMILCCAIRR-NRDMV 226
>sp|P40240|CD9_MOUSE CD9 antigen Length = 226 Score = 73.2 bits (178), Expect = 9e-13 Identities = 53/220 (24%), Positives = 85/220 (38%), Gaps = 8/220 (3%) Frame = +3 Query: 129 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNMGA---DGSAVVIAFYVTMGVGAFT 299 CI+ L+ FNFIF L K++ + S+ Y+ +G GA Sbjct: 9 CIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQENNHSSFYTGVYILIGAGALM 68 Query: 300 LIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKGKN 479 ++VG GCCGA ES C+LG + V + +KD V ++ ++ Sbjct: 69 MLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAVWGYTHKDEVIKELQEFYKDTYQ 128 Query: 480 EISGDNKNNNGHWMHEAHKYLQCCGNKGPSDYSSPPKSCCLADNCENVN-----SMKGCG 644 ++ ++ + H L CCG GP + ++D C +K C Sbjct: 129 KLRSKDEPQR-ETLKAIHMALDCCGIAGPLEQ-------FISDTCPKKQLLESFQVKPCP 180 Query: 645 ETWKELIQNRWILFASVXXXXXXXXXXXXXFSMCLCCTAR 764 E E+ N++ + +V FSM LCC R Sbjct: 181 EAISEVFNNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIR 220
>sp|O97703|CD81_CERAE CD81 antigen Length = 236 Score = 72.4 bits (176), Expect = 1e-12 Identities = 54/227 (23%), Positives = 86/227 (37%), Gaps = 11/227 (4%) Frame = +3 Query: 120 CHSCIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNM-------GADGSAVVIAFYVT 278 C CI+ L+ +FNF+F L N+ + + Y+ Sbjct: 6 CTKCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTNLLYLELGDKPAPNTFYVGIYIL 65 Query: 279 MGVGAFTLIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVEN 458 + VGA + VG GC GA ES CLLGT+ G+ F+ KD + V+ Sbjct: 66 IAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQ 125 Query: 459 KFEKG-KNEISGDNKNNNGHWMHEAHKYLQCCGNKGPSDYSSPPKSCCLADNCENVNS-- 629 +++ + + D+ NN + H+ L CCG+ + ++ L + N+ S Sbjct: 126 FYDQALQQAVVDDDANNAKAVVKTFHETLDCCGSSTLAALTTSVLKNNLCPSGSNIISNL 185 Query: 630 -MKGCGETWKELIQNRWILFASVXXXXXXXXXXXXXFSMCLCCTARS 767 K C + EL + L SM LCC R+ Sbjct: 186 LKKDCHQKIDELFSGKLYLIGIAAIVVAVIMIFEMILSMVLCCGIRN 232
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,916,184
Number of Sequences: 369166
Number of extensions: 1603777
Number of successful extensions: 4234
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4032
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4170
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8293644780
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Cluster detail
