Planaria EST Database


DrC_01116

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01116
         (846 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q8WMQ3|CD9_PIG  CD9 antigen                                     82   2e-15
sp|Q922J6|TSN2_MOUSE  Tetraspanin-2 (Tspan-2)                      78   3e-14
sp|Q9JJW1|TSN2_RAT  Tetraspanin-2 (Tspan-2)                        77   5e-14
sp|O60636|TSN2_HUMAN  Tetraspanin-2 (Tspan-2)                      76   1e-13
sp|P40239|CD9_FELCA  CD9 antigen                                   75   2e-13
sp|P30409|CD9_CERAE  CD9 antigen (27 kDa diphtheria toxin re...    75   3e-13
sp|P21926|CD9_HUMAN  CD9 antigen (p24) (Leukocyte antigen MI...    75   3e-13
sp|P30932|CD9_BOVIN  CD9 antigen                                   74   7e-13
sp|P40240|CD9_MOUSE  CD9 antigen                                   73   9e-13
sp|O97703|CD81_CERAE  CD81 antigen                                 72   1e-12
>sp|Q8WMQ3|CD9_PIG CD9 antigen
          Length = 226

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 59/220 (26%), Positives = 89/220 (40%), Gaps = 8/220 (3%)
 Frame = +3

Query: 129 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNMGA---DGSAVVIAFYVTMGVGAFT 299
           CI+ L+  FNFIF L                  K++     + S+     Y+ +G GA  
Sbjct: 9   CIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQENNNSSFYTGVYILIGAGALM 68

Query: 300 LIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKGKN 479
           ++VG  GCCGA  ES C+LG +               +  + +KD V   V++ +    N
Sbjct: 69  MVVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDQVIKEVQDFYRDTYN 128

Query: 480 EISGDNKNNNGHWMHEAHKYLQCCGNKGPSDYSSPPKSCCLADNCENVN-----SMKGCG 644
           ++ G + +     +   H  L CCG  G  +         LAD C   +      MK C 
Sbjct: 129 KLKGKD-DPQRETLKAIHYALDCCGLMGEVEQ-------LLADICPQRDVLSSLPMKPCP 180

Query: 645 ETWKELIQNRWILFASVXXXXXXXXXXXXXFSMCLCCTAR 764
           E  KE+ QN++ +  +V             FSM LCC  R
Sbjct: 181 EAIKEVFQNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIR 220
>sp|Q922J6|TSN2_MOUSE Tetraspanin-2 (Tspan-2)
          Length = 221

 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 56/216 (25%), Positives = 89/216 (41%), Gaps = 3/216 (1%)
 Frame = +3

Query: 129 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNMGADGSA---VVIAFYVTMGVGAFT 299
           CI+ L++ FN +F L                  K++ ++  +     +  YV +G GA  
Sbjct: 10  CIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGTMKDLSSEDKSPEYFYVGLYVLVGAGALM 69

Query: 300 LIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKGKN 479
           + VG  GCCGA  ES C+LG++              GV  F+ KD    +V++ +E+  +
Sbjct: 70  MTVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKDVAIRHVQSMYEEAYS 129

Query: 480 EISGDNKNNNGHWMHEAHKYLQCCGNKGPSDYSSPPKSCCLADNCENVNSMKGCGETWKE 659
           +   D    NG  +   H   QCCG K  S+   P  +C      + +   K C +  + 
Sbjct: 130 DYLKDRARGNG-TLITFHSAFQCCG-KESSEQVQP--TC-----PKELPGHKNCIDKIET 180

Query: 660 LIQNRWILFASVXXXXXXXXXXXXXFSMCLCCTARS 767
           +I  +  L   V             FSM LCC  R+
Sbjct: 181 VISAKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRN 216
>sp|Q9JJW1|TSN2_RAT Tetraspanin-2 (Tspan-2)
          Length = 221

 Score = 77.4 bits (189), Expect = 5e-14
 Identities = 56/216 (25%), Positives = 89/216 (41%), Gaps = 3/216 (1%)
 Frame = +3

Query: 129 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNMGADGSA---VVIAFYVTMGVGAFT 299
           CI+ L++ FN +F L                  K++ ++  +     +  YV +G GA  
Sbjct: 10  CIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGTIKDLSSEEKSPEYFYVGLYVLVGAGALM 69

Query: 300 LIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKGKN 479
           + VG  GCCGA  ES C+LG++              GV  F+ KD    +V++ +E+  +
Sbjct: 70  MAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKDVAIRHVQSMYEEAYS 129

Query: 480 EISGDNKNNNGHWMHEAHKYLQCCGNKGPSDYSSPPKSCCLADNCENVNSMKGCGETWKE 659
           +   D    NG  +   H   QCCG K  S+   P  +C      + +   K C +  + 
Sbjct: 130 DYVRDRGRGNG-TLITFHSAFQCCG-KESSEQVQP--TC-----PKELPGHKNCIDKIET 180

Query: 660 LIQNRWILFASVXXXXXXXXXXXXXFSMCLCCTARS 767
           +I  +  L   V             FSM LCC  R+
Sbjct: 181 IISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRN 216
>sp|O60636|TSN2_HUMAN Tetraspanin-2 (Tspan-2)
          Length = 221

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 56/216 (25%), Positives = 86/216 (39%), Gaps = 3/216 (1%)
 Frame = +3

Query: 129 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNMGADGSA---VVIAFYVTMGVGAFT 299
           CI+ L++ FN +F L                  K + ++  +     +  YV +G GA  
Sbjct: 10  CIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLYVLVGAGALM 69

Query: 300 LIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKGKN 479
           + VG  GCCGA  ES C+LG++              GV  F+ K     +V+  +E+  N
Sbjct: 70  MAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAYN 129

Query: 480 EISGDNKNNNGHWMHEAHKYLQCCGNKGPSDYSSPPKSCCLADNCENVNSMKGCGETWKE 659
           +   D    NG  +   H   QCCG K  S+   P  +C      + +   K C +  + 
Sbjct: 130 DYLKDRGKGNG-TLITFHSTFQCCG-KESSEQVQP--TC-----PKELLGHKNCIDEIET 180

Query: 660 LIQNRWILFASVXXXXXXXXXXXXXFSMCLCCTARS 767
           +I  +  L   V             FSM LCC  R+
Sbjct: 181 IISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRN 216
>sp|P40239|CD9_FELCA CD9 antigen
          Length = 226

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 53/215 (24%), Positives = 86/215 (40%), Gaps = 3/215 (1%)
 Frame = +3

Query: 129 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNM---GADGSAVVIAFYVTMGVGAFT 299
           CI+ L+  FNFIF L                  K++    +  S+     Y+ +G GA  
Sbjct: 9   CIKYLLFGFNFIFWLAGIAVLAVGLWLRFDSQTKSIFEQDSQPSSFYTGVYILIGAGALM 68

Query: 300 LIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKGKN 479
           ++VG  GCCGA  ES C+LG +               +  + +KD V   V+  ++   N
Sbjct: 69  MLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDEVIQEVQEFYKDTYN 128

Query: 480 EISGDNKNNNGHWMHEAHKYLQCCGNKGPSDYSSPPKSCCLADNCENVNSMKGCGETWKE 659
           ++   ++      +   H  L CCG  G  +        C   +  +  ++K C E  KE
Sbjct: 129 KLKSKDEPQR-DTLKAIHYALDCCGLAGGVEQFI--SDICPQKDILSSITVKPCPEAIKE 185

Query: 660 LIQNRWILFASVXXXXXXXXXXXXXFSMCLCCTAR 764
           +  N++ +  +V             FSM LCC  R
Sbjct: 186 VFHNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIR 220
>sp|P30409|CD9_CERAE CD9 antigen (27 kDa diphtheria toxin receptor-associated protein)
           (DRAP27)
          Length = 228

 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 52/217 (23%), Positives = 85/217 (39%), Gaps = 5/217 (2%)
 Frame = +3

Query: 129 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNM-----GADGSAVVIAFYVTMGVGA 293
           CI+ L+  FNFIF L                  K++       + S+     Y+ +G GA
Sbjct: 9   CIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQETNNNNSSFYTGVYILIGAGA 68

Query: 294 FTLIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKG 473
             ++VG  GCCGA  ES C+LG +               +  + +KD V   V+  ++  
Sbjct: 69  LMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDEVIKEVQEFYKDT 128

Query: 474 KNEISGDNKNNNGHWMHEAHKYLQCCGNKGPSDYSSPPKSCCLADNCENVNSMKGCGETW 653
            N++   ++      +   H  L CCG  G  +        C   +     ++K C +  
Sbjct: 129 YNKLKTKDEPQR-ETLKAIHYALDCCGLAGGVEQFI--SDICPKKDVLETFTIKSCPDAI 185

Query: 654 KELIQNRWILFASVXXXXXXXXXXXXXFSMCLCCTAR 764
           KE+  N++ +  +V             FSM LCC  R
Sbjct: 186 KEVFDNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIR 222
>sp|P21926|CD9_HUMAN CD9 antigen (p24) (Leukocyte antigen MIC3) (Motility-related
           protein) (MRP-1) (Tetraspanin-29) (Tspan-29)
          Length = 228

 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 52/217 (23%), Positives = 85/217 (39%), Gaps = 5/217 (2%)
 Frame = +3

Query: 129 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNM-----GADGSAVVIAFYVTMGVGA 293
           CI+ L+  FNFIF L                  K++       + S+     Y+ +G GA
Sbjct: 9   CIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQETNNNNSSFYTGVYILIGAGA 68

Query: 294 FTLIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKG 473
             ++VG  GCCGA  ES C+LG +               +  + +KD V   V+  ++  
Sbjct: 69  LMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDEVIKEVQEFYKDT 128

Query: 474 KNEISGDNKNNNGHWMHEAHKYLQCCGNKGPSDYSSPPKSCCLADNCENVNSMKGCGETW 653
            N++   ++      +   H  L CCG  G  +        C   +     ++K C +  
Sbjct: 129 YNKLKTKDEPQR-ETLKAIHYALNCCGLAGGVEQFI--SDICPKKDVLETFTVKSCPDAI 185

Query: 654 KELIQNRWILFASVXXXXXXXXXXXXXFSMCLCCTAR 764
           KE+  N++ +  +V             FSM LCC  R
Sbjct: 186 KEVFDNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIR 222
>sp|P30932|CD9_BOVIN CD9 antigen
          Length = 226

 Score = 73.6 bits (179), Expect = 7e-13
 Identities = 58/226 (25%), Positives = 95/226 (42%), Gaps = 7/226 (3%)
 Frame = +3

Query: 129 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNMGA---DGSAVVIAFYVTMGVGAFT 299
           CI+ L+  FNFIF L                  K++     + S+     Y+ +G GA  
Sbjct: 9   CIKYLLFGFNFIFWLAGIAVLSVGLWLRFDSQTKSIFEQENNDSSFYTGVYILIGAGALM 68

Query: 300 LIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKGKN 479
           ++VG  GCCGA  ES C+LG +               +  + +K+ V   V+  +E   N
Sbjct: 69  MLVGFLGCCGAVQESQCMLGLFFSFLLVIFAIEVAAAIWGYSHKEEVIKEVQKFYEDTYN 128

Query: 480 EISGDNKNNNGHWMHEAHKYLQCCGNKG-PSDY---SSPPKSCCLADNCENVNSMKGCGE 647
           ++   ++      +   H  L CCG  G P  +   + PPK+  L D+ +     + C E
Sbjct: 129 KLKNKDEPQR-ETLKAIHIALDCCGLTGVPEQFLTDTCPPKN--LIDSLKT----RPCPE 181

Query: 648 TWKELIQNRWILFASVXXXXXXXXXXXXXFSMCLCCTARSIDYDMV 785
              E+ ++++ +  +V             FSM LCC  R  + DMV
Sbjct: 182 AIDEIFRSKFHIIGAVGIGIAVVMIFGMVFSMILCCAIRR-NRDMV 226
>sp|P40240|CD9_MOUSE CD9 antigen
          Length = 226

 Score = 73.2 bits (178), Expect = 9e-13
 Identities = 53/220 (24%), Positives = 85/220 (38%), Gaps = 8/220 (3%)
 Frame = +3

Query: 129 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNMGA---DGSAVVIAFYVTMGVGAFT 299
           CI+ L+  FNFIF L                  K++     + S+     Y+ +G GA  
Sbjct: 9   CIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQENNHSSFYTGVYILIGAGALM 68

Query: 300 LIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKGKN 479
           ++VG  GCCGA  ES C+LG +               V  + +KD V   ++  ++    
Sbjct: 69  MLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAVWGYTHKDEVIKELQEFYKDTYQ 128

Query: 480 EISGDNKNNNGHWMHEAHKYLQCCGNKGPSDYSSPPKSCCLADNCENVN-----SMKGCG 644
           ++   ++      +   H  L CCG  GP +         ++D C          +K C 
Sbjct: 129 KLRSKDEPQR-ETLKAIHMALDCCGIAGPLEQ-------FISDTCPKKQLLESFQVKPCP 180

Query: 645 ETWKELIQNRWILFASVXXXXXXXXXXXXXFSMCLCCTAR 764
           E   E+  N++ +  +V             FSM LCC  R
Sbjct: 181 EAISEVFNNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIR 220
>sp|O97703|CD81_CERAE CD81 antigen
          Length = 236

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 54/227 (23%), Positives = 86/227 (37%), Gaps = 11/227 (4%)
 Frame = +3

Query: 120 CHSCIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNM-------GADGSAVVIAFYVT 278
           C  CI+ L+ +FNF+F L                   N+           +   +  Y+ 
Sbjct: 6   CTKCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTNLLYLELGDKPAPNTFYVGIYIL 65

Query: 279 MGVGAFTLIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVEN 458
           + VGA  + VG  GC GA  ES CLLGT+              G+  F+ KD +   V+ 
Sbjct: 66  IAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQ 125

Query: 459 KFEKG-KNEISGDNKNNNGHWMHEAHKYLQCCGNKGPSDYSSPPKSCCLADNCENVNS-- 629
            +++  +  +  D+ NN    +   H+ L CCG+   +  ++      L  +  N+ S  
Sbjct: 126 FYDQALQQAVVDDDANNAKAVVKTFHETLDCCGSSTLAALTTSVLKNNLCPSGSNIISNL 185

Query: 630 -MKGCGETWKELIQNRWILFASVXXXXXXXXXXXXXFSMCLCCTARS 767
             K C +   EL   +  L                  SM LCC  R+
Sbjct: 186 LKKDCHQKIDELFSGKLYLIGIAAIVVAVIMIFEMILSMVLCCGIRN 232
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,916,184
Number of Sequences: 369166
Number of extensions: 1603777
Number of successful extensions: 4234
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4032
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4170
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8293644780
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_01116

  1. Dr_sW_028_G18
  2. Dr_sW_022_O11
  3. Dr_sW_013_F08
  4. Dr_sW_028_C09