Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_O11
(508 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q922J6|TSN2_MOUSE Tetraspanin-2 (Tspan-2) 65 1e-10
sp|Q9JJW1|TSN2_RAT Tetraspanin-2 (Tspan-2) 64 2e-10
sp|O60636|TSN2_HUMAN Tetraspanin-2 (Tspan-2) 63 5e-10
sp|P60033|CD81_HUMAN CD81 antigen (26 kDa cell surface prot... 58 1e-08
sp|Q9N0J9|CD81_SAGOE CD81 protein 58 1e-08
sp|O97703|CD81_CERAE CD81 antigen 58 1e-08
sp|Q62745|CD81_RAT CD81 antigen (26 kDa cell surface protei... 57 3e-08
sp|P35762|CD81_MOUSE CD81 antigen (26 kDa cell surface prot... 56 6e-08
sp|Q8WMQ3|CD9_PIG CD9 antigen 55 7e-08
sp|P40239|CD9_FELCA CD9 antigen 54 3e-07
>sp|Q922J6|TSN2_MOUSE Tetraspanin-2 (Tspan-2)
Length = 221
Score = 64.7 bits (156), Expect = 1e-10
Identities = 35/131 (26%), Positives = 58/131 (44%), Gaps = 3/131 (2%)
Frame = +3
Query: 96 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNMGADGSA---VVIAFYVTMGVGAFT 266
CI+ L++ FN +F L K++ ++ + + YV +G GA
Sbjct: 10 CIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGTMKDLSSEDKSPEYFYVGLYVLVGAGALM 69
Query: 267 LIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKGKN 446
+ VG GCCGA ES C+LG++ GV F+ KD +V++ +E+ +
Sbjct: 70 MTVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKDVAIRHVQSMYEEAYS 129
Query: 447 EISGDNKNNNG 479
+ D NG
Sbjct: 130 DYLKDRARGNG 140
>sp|Q9JJW1|TSN2_RAT Tetraspanin-2 (Tspan-2)
Length = 221
Score = 63.9 bits (154), Expect = 2e-10
Identities = 35/131 (26%), Positives = 58/131 (44%), Gaps = 3/131 (2%)
Frame = +3
Query: 96 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNMGADGSA---VVIAFYVTMGVGAFT 266
CI+ L++ FN +F L K++ ++ + + YV +G GA
Sbjct: 10 CIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGTIKDLSSEEKSPEYFYVGLYVLVGAGALM 69
Query: 267 LIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKGKN 446
+ VG GCCGA ES C+LG++ GV F+ KD +V++ +E+ +
Sbjct: 70 MAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKDVAIRHVQSMYEEAYS 129
Query: 447 EISGDNKNNNG 479
+ D NG
Sbjct: 130 DYVRDRGRGNG 140
>sp|O60636|TSN2_HUMAN Tetraspanin-2 (Tspan-2)
Length = 221
Score = 62.8 bits (151), Expect = 5e-10
Identities = 35/131 (26%), Positives = 55/131 (41%), Gaps = 3/131 (2%)
Frame = +3
Query: 96 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNMGADGSA---VVIAFYVTMGVGAFT 266
CI+ L++ FN +F L K + ++ + + YV +G GA
Sbjct: 10 CIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLYVLVGAGALM 69
Query: 267 LIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKGKN 446
+ VG GCCGA ES C+LG++ GV F+ K +V+ +E+ N
Sbjct: 70 MAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAYN 129
Query: 447 EISGDNKNNNG 479
+ D NG
Sbjct: 130 DYLKDRGKGNG 140
>sp|P60033|CD81_HUMAN CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the
antiproliferative antibody 1) (Tetraspanin-28)
(Tspan-28)
sp|P60034|CD81_PANTR CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the
antiproliferative antibody 1)
Length = 236
Score = 57.8 bits (138), Expect = 1e-08
Identities = 35/137 (25%), Positives = 55/137 (40%), Gaps = 7/137 (5%)
Frame = +3
Query: 87 CHSCIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNM-------GADGSAVVIAFYVT 245
C CI+ L+ +FNF+F L N+ + + Y+
Sbjct: 6 CTKCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTNLLYLELGDKPAPNTFYVGIYIL 65
Query: 246 MGVGAFTLIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVEN 425
+ VGA + VG GC GA ES CLLGT+ G+ F+ KD + V+
Sbjct: 66 IAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQ 125
Query: 426 KFEKGKNEISGDNKNNN 476
+++ + D+ NN
Sbjct: 126 FYDQALQQAVVDDDANN 142
>sp|Q9N0J9|CD81_SAGOE CD81 protein
Length = 236
Score = 57.8 bits (138), Expect = 1e-08
Identities = 35/137 (25%), Positives = 55/137 (40%), Gaps = 7/137 (5%)
Frame = +3
Query: 87 CHSCIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNM-------GADGSAVVIAFYVT 245
C CI+ L+ +FNF+F L N+ + + Y+
Sbjct: 6 CTKCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTNLLYLELGDKPAPNTFYVGIYIL 65
Query: 246 MGVGAFTLIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVEN 425
+ VGA + VG GC GA ES CLLGT+ G+ F+ KD + V+
Sbjct: 66 IAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQ 125
Query: 426 KFEKGKNEISGDNKNNN 476
+++ + D+ NN
Sbjct: 126 FYDQALQQAVVDDDANN 142
>sp|O97703|CD81_CERAE CD81 antigen
Length = 236
Score = 57.8 bits (138), Expect = 1e-08
Identities = 35/137 (25%), Positives = 55/137 (40%), Gaps = 7/137 (5%)
Frame = +3
Query: 87 CHSCIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNM-------GADGSAVVIAFYVT 245
C CI+ L+ +FNF+F L N+ + + Y+
Sbjct: 6 CTKCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTNLLYLELGDKPAPNTFYVGIYIL 65
Query: 246 MGVGAFTLIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVEN 425
+ VGA + VG GC GA ES CLLGT+ G+ F+ KD + V+
Sbjct: 66 IAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQ 125
Query: 426 KFEKGKNEISGDNKNNN 476
+++ + D+ NN
Sbjct: 126 FYDQALQQAVVDDDANN 142
>sp|Q62745|CD81_RAT CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the
antiproliferative antibody 1)
Length = 236
Score = 56.6 bits (135), Expect = 3e-08
Identities = 35/137 (25%), Positives = 54/137 (39%), Gaps = 7/137 (5%)
Frame = +3
Query: 87 CHSCIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNM-------GADGSAVVIAFYVT 245
C CI+ L+ +FNF+F L + S + Y+
Sbjct: 6 CTKCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTTLLYLELGDKPAPSTFYVGIYIL 65
Query: 246 MGVGAFTLIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVEN 425
+ VGA + VG GC GA ES CLLGT+ G+ F+ KD + V+
Sbjct: 66 IAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQ 125
Query: 426 KFEKGKNEISGDNKNNN 476
+++ + D+ NN
Sbjct: 126 FYDQALQQAVMDDDANN 142
>sp|P35762|CD81_MOUSE CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the
antiproliferative antibody 1)
Length = 236
Score = 55.8 bits (133), Expect = 6e-08
Identities = 34/137 (24%), Positives = 55/137 (40%), Gaps = 7/137 (5%)
Frame = +3
Query: 87 CHSCIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNM-------GADGSAVVIAFYVT 245
C CI+ L+ +FNF+F L ++ + + Y+
Sbjct: 6 CTKCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTSLLYLELGNKPAPNTFYVGIYIL 65
Query: 246 MGVGAFTLIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVEN 425
+ VGA + VG GC GA ES CLLGT+ G+ F+ KD + V+
Sbjct: 66 IAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQ 125
Query: 426 KFEKGKNEISGDNKNNN 476
+++ + D+ NN
Sbjct: 126 FYDQALQQAVMDDDANN 142
>sp|Q8WMQ3|CD9_PIG CD9 antigen
Length = 226
Score = 55.5 bits (132), Expect = 7e-08
Identities = 33/124 (26%), Positives = 53/124 (42%), Gaps = 3/124 (2%)
Frame = +3
Query: 96 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNMGA---DGSAVVIAFYVTMGVGAFT 266
CI+ L+ FNFIF L K++ + S+ Y+ +G GA
Sbjct: 9 CIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQENNNSSFYTGVYILIGAGALM 68
Query: 267 LIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKGKN 446
++VG GCCGA ES C+LG + + + +KD V V++ + N
Sbjct: 69 MVVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDQVIKEVQDFYRDTYN 128
Query: 447 EISG 458
++ G
Sbjct: 129 KLKG 132
>sp|P40239|CD9_FELCA CD9 antigen
Length = 226
Score = 53.5 bits (127), Expect = 3e-07
Identities = 32/127 (25%), Positives = 54/127 (42%), Gaps = 3/127 (2%)
Frame = +3
Query: 96 CIRILMMIFNFIFVLCXXXXXXXXXXXXXXXXXKNM---GADGSAVVIAFYVTMGVGAFT 266
CI+ L+ FNFIF L K++ + S+ Y+ +G GA
Sbjct: 9 CIKYLLFGFNFIFWLAGIAVLAVGLWLRFDSQTKSIFEQDSQPSSFYTGVYILIGAGALM 68
Query: 267 LIVGACGCCGAYHESPCLLGTYXXXXXXXXXXXXXXGVLVFLYKDTVKAYVENKFEKGKN 446
++VG GCCGA ES C+LG + + + +KD V V+ ++ N
Sbjct: 69 MLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDEVIQEVQEFYKDTYN 128
Query: 447 EISGDNK 467
++ ++
Sbjct: 129 KLKSKDE 135
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,837,524
Number of Sequences: 369166
Number of extensions: 762384
Number of successful extensions: 2371
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2291
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2352
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3206272875
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)