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Planaria EST Database

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01061
         (590 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P31226|SAX_RANCA  Saxiphilin precursor (SAX)                    58   2e-08
sp|P06882|THYG_RAT  Thyroglobulin precursor                        58   2e-08
sp|O08710|THYG_MOUSE  Thyroglobulin precursor                      58   2e-08
sp|P01267|THYG_BOVIN  Thyroglobulin precursor                      55   1e-07
sp|P01266|THYG_HUMAN  Thyroglobulin precursor                      55   1e-07
sp|O88322|NID2_MOUSE  Nidogen-2 precursor (NID-2) (Entactin-2)     52   8e-07
sp|Q14112|NID2_HUMAN  Nidogen-2 precursor (NID-2) (Osteonido...    49   7e-06
sp|P81439|EQST_ACTEQ  Equistatin                                   49   7e-06
sp|Q9BQ16|TICN3_HUMAN  Testican-3 precursor (SPARC/osteonect...    43   5e-04
sp|Q8BKV0|TICN3_MOUSE  Testican-3 precursor (SPARC/osteonect...    43   5e-04

>sp|P31226|SAX_RANCA Saxiphilin precursor (SAX)
          Length = 844

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 44/148 (29%), Positives = 65/148 (43%), Gaps = 13/148 (8%)
 Frame = +2

Query: 77  NNDQCNVGLICDEVCKEDNNAPNCFKRHLDARRLIKSGAVDVTFPFCEDTGMYKPVQCVG 256
           + D  N+  I  E    + +   C K    A   +    +    P C++ G Y+P QC G
Sbjct: 87  SKDPYNLKPIIAEPYSSNRDLQKCLKERQQA---LAKKMIGHYIPQCDEKGNYQPQQCHG 143

Query: 257 AA--CWCVEESGDEIEGYITGIEESYGKTCN------CAKDKLEY--SQRKIVGRTF-RC 403
           +   CWCV   G++I G  T   ++   TC       C K++        K++GR   +C
Sbjct: 144 STGHCWCVNAMGEKISGTNTPPGQTRA-TCERHELPKCLKERQVALGGDEKVLGRFVPQC 202

Query: 404 DHLGNYEKVQCHGSICY--CADLSGNKI 481
           D  GNYE  Q HGS  Y  C +  G +I
Sbjct: 203 DEKGNYEPQQFHGSTGYSWCVNAIGEEI 230

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 5/64 (7%)
 Frame = +2

Query: 125 EDNNAPNCFKRHLDARRLIKSGAVDVT---FPFCEDTGMYKPVQCVGAA--CWCVEESGD 289
           E +  P C K     R++   G   V     P C++ G Y+P Q  G+    WCV   G+
Sbjct: 173 ERHELPKCLKE----RQVALGGDEKVLGRFVPQCDEKGNYEPQQFHGSTGYSWCVNAIGE 228

Query: 290 EIEG 301
           EI G
Sbjct: 229 EIAG 232

>sp|P06882|THYG_RAT Thyroglobulin precursor
          Length = 2768

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 5/97 (5%)
 Frame = +2

Query: 209 PFCEDTGMYKPVQCVGAACWCVEESGDEIEG-YITGIEESYGKTCNCAKDKLE-YSQRKI 382
           P C   G Y+ +QC    CWCV   G E+EG  ++G        C   + +++  +  + 
Sbjct: 618 PSCTAEGSYEDIQCYAGECWCVNSQGKEVEGSRVSGGHPRCPTKCEKQRAQMQNLAGAQP 677

Query: 383 VGRTF---RCDHLGNYEKVQCHGSICYCADLSGNKIP 484
            G +F    C   G +  VQC  S CYC D  G  IP
Sbjct: 678 AGSSFFVPTCTSEGYFLPVQCFNSECYCVDAEGQVIP 714

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 13/108 (12%)
 Frame = +2

Query: 197 DVTFPFCEDTGMYKPVQCV--GAACWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEYS 370
           D   P C + G ++ VQC   G +CWCV+  G E+ G         G+   C      + 
Sbjct: 47  DEYVPQCSEDGSFQTVQCQNDGQSCWCVDSDGTEVPG-----SRQLGRPTACLSFCQLHK 101

Query: 371 QRKIVGRTF---------RCDHLGNYEKVQC--HGSICYCADLSGNKI 481
           QR ++             +C   GNY  VQC      C+C D  G ++
Sbjct: 102 QRILLSSYINSTDALYLPQCQDSGNYAPVQCDLQQVQCWCVDTEGMEV 149

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 31/102 (30%), Positives = 46/102 (45%), Gaps = 10/102 (9%)
 Frame = +2

Query: 161 LDARRLIKSGAVDVT----FPFCEDTGMYKPVQC--VGAACWCVEESGDEIEGYITGIEE 322
           L  +R++ S  ++ T     P C+D+G Y PVQC      CWCV+  G E+ G       
Sbjct: 99  LHKQRILLSSYINSTDALYLPQCQDSGNYAPVQCDLQQVQCWCVDTEGMEVYG-----TR 153

Query: 323 SYGKTCNCAKDKLEYSQRKIVG----RTFRCDHLGNYEKVQC 436
             G+   C +     S+R + G       +CD  G +  VQC
Sbjct: 154 QQGRPTRCPRSCEIRSRRLLHGVGDKSPPQCDADGEFMPVQC 195

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 33/103 (32%), Positives = 46/103 (44%), Gaps = 4/103 (3%)
 Frame = +2

Query: 188  GAVDVTFPFCEDTGMYKPVQCVGAACWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEY 367
            G  D+  P C  TG Y   Q  G   WCV+ S  E     T         C+  K ++  
Sbjct: 1100 GPGDLFTPVCLQTGEYVRQQTSGTGAWCVDPSSGEGVPTNTNSSAQCPGLCDALKSRV-L 1158

Query: 368  SQRKIVGRTFRCDHL-GNYEKVQC---HGSICYCADLSGNKIP 484
            S++  +G T  C+ L G +  VQC    GS C+C   SG ++P
Sbjct: 1159 SRKVGLGYTPVCEALDGGFSPVQCDLAQGS-CWCVLASGEEVP 1200

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
 Frame = +2

Query: 209 PFCEDTGMYKPVQC-VGAACWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEYSQRK 379
           P C   G Y+ VQC +   CWCV+  G EI G         G+   CAKD+   S+R+
Sbjct: 318 PSCHRDGHYQTVQCQMERMCWCVDAQGIEIPG-----TRQQGQPLFCAKDQSCASERQ 370

 Score = 37.0 bits (84), Expect = 0.037
 Identities = 31/110 (28%), Positives = 44/110 (40%), Gaps = 16/110 (14%)
 Frame = +2

Query: 209  PFCEDTGMYKPVQCVGAA--CWCVEESGDEIEGYI-----------TGIEESYGKTCNCA 349
            P C   G ++PVQC      CWCV+  G+ I G +           T  E S       A
Sbjct: 1030 PQCNTIGGWEPVQCHPGTGQCWCVDGWGELIPGSLMARSSQMPQCPTSCELSRANGLISA 1089

Query: 350  KDKLEYSQRKIVGRTFR--CDHLGNYEKVQCHGSICYCAD-LSGNKIPTS 490
              +  + +    G  F   C   G Y + Q  G+  +C D  SG  +PT+
Sbjct: 1090 WKQAGHQRNPGPGDLFTPVCLQTGEYVRQQTSGTGAWCVDPSSGEGVPTN 1139

 Score = 36.2 bits (82), Expect = 0.063
 Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
 Frame = +2

Query: 146 CFKRHLDARRLIKSGAVDVTF--PFCEDTGMYKPVQCVGAACWCVEESGDEIEGYITGIE 319
           C K+    + L  +     +F  P C   G + PVQC  + C+CV+  G  I G  + I 
Sbjct: 662 CEKQRAQMQNLAGAQPAGSSFFVPTCTSEGYFLPVQCFNSECYCVDAEGQVIPGTQSTIG 721

Query: 320 E 322
           E
Sbjct: 722 E 722

 Score = 33.9 bits (76), Expect = 0.31
 Identities = 16/34 (47%), Positives = 20/34 (58%), Gaps = 3/34 (8%)
 Frame = +2

Query: 209  PFCEDT-GMYKPVQC--VGAACWCVEESGDEIEG 301
            P CE   G + PVQC     +CWCV  SG+E+ G
Sbjct: 1168 PVCEALDGGFSPVQCDLAQGSCWCVLASGEEVPG 1201

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 13/37 (35%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
 Frame = +2

Query: 386 GRTF--RCDHLGNYEKVQCHGSICYCADLSGNKIPTS 490
           GR F   C   G+YE +QC+   C+C +  G ++  S
Sbjct: 613 GRFFVPSCTAEGSYEDIQCYAGECWCVNSQGKEVEGS 649

>sp|O08710|THYG_MOUSE Thyroglobulin precursor
          Length = 2766

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 42/137 (30%), Positives = 58/137 (42%), Gaps = 10/137 (7%)
 Frame = +2

Query: 209  PFCEDTGMYKPVQCVGAACWCVEESGDEIEG-YITGIEESYGKTCNCAKDKLE-YSQRKI 382
            P C   G Y+ +QC    CWCV+  G E++G  + G        C   + +++  +  + 
Sbjct: 618  PSCTAGGSYEDIQCYAGECWCVDSRGKELDGSRVRGGRPRCPTKCEKQRAQMQSLASAQP 677

Query: 383  VGRTF---RCDHLGNYEKVQCHGSICYCADLSGNKIP-TSPYVDIANFNSLKCD*RKYKY 550
             G +F    C   G +  VQC  S CYC D  G  IP T   V  A      C  +  + 
Sbjct: 678  AGSSFFVPTCTREGYFLPVQCFNSECYCVDTEGQVIPGTQSTVGEAKQCPSVCQLQAEQA 737

Query: 551  LL----VTRQNSSAVPS 589
             L    V   NSS VPS
Sbjct: 738  FLGVVGVLLSNSSMVPS 754

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 30/104 (28%), Positives = 44/104 (42%), Gaps = 13/104 (12%)
 Frame = +2

Query: 209 PFCEDTGMYKPVQCV--GAACWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEYSQRKI 382
           P C + G ++ VQC   G +CWCV+  G E+ G         G+   C      + QR +
Sbjct: 51  PQCSEDGSFQTVQCQNDGQSCWCVDSDGREVPG-----SRQLGRPTVCLSFCQLHKQRIL 105

Query: 383 VGRTF---------RCDHLGNYEKVQC--HGSICYCADLSGNKI 481
           +G            +C   GNY  VQC      C+C D  G ++
Sbjct: 106 LGSYINSTDALYLPQCQDSGNYAPVQCDLQRVQCWCVDTEGMEV 149

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 6/82 (7%)
 Frame = +2

Query: 209 PFCEDTGMYKPVQC--VGAACWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEYSQRKI 382
           P C+D+G Y PVQC      CWCV+  G E+ G         G+   C +     ++R +
Sbjct: 119 PQCQDSGNYAPVQCDLQRVQCWCVDTEGMEVYG-----TRQQGRPTRCPRSCEIRNRRLL 173

Query: 383 VGRTFR----CDHLGNYEKVQC 436
            G   R    C   G +  VQC
Sbjct: 174 HGVGDRSPPQCTADGEFMPVQC 195

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 4/103 (3%)
 Frame = +2

Query: 188  GAVDVTFPFCEDTGMYKPVQCVGAACWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEY 367
            G  D+  P C  TG Y   Q  G   WCV+ +  E     T         C+  K +   
Sbjct: 1100 GPGDLFIPVCLQTGEYVRKQTSGTGTWCVDPASGEGMPVNTNGSAQCPGLCDVLKSR-AL 1158

Query: 368  SQRKIVGRTFRCDHL-GNYEKVQC---HGSICYCADLSGNKIP 484
            S++  +G +  C+ L G +  VQC    GS C+C   SG ++P
Sbjct: 1159 SRKVGLGYSPVCEALDGAFSPVQCDLAQGS-CWCVLGSGEEVP 1200

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 18/51 (35%), Positives = 24/51 (47%), Gaps = 1/51 (1%)
 Frame = +2

Query: 209 PFCEDTGMYKPVQC-VGAACWCVEESGDEIEGYITGIEESYGKTCNCAKDK 358
           P C   G Y+ VQC     CWCV+  G E+ G         G+  +CA D+
Sbjct: 318 PRCHRDGHYQTVQCQTEGMCWCVDAQGREVPG-----TRQQGQPPSCAADQ 363

 Score = 34.3 bits (77), Expect = 0.24
 Identities = 16/34 (47%), Positives = 20/34 (58%), Gaps = 3/34 (8%)
 Frame = +2

Query: 209  PFCEDT-GMYKPVQC--VGAACWCVEESGDEIEG 301
            P CE   G + PVQC     +CWCV  SG+E+ G
Sbjct: 1168 PVCEALDGAFSPVQCDLAQGSCWCVLGSGEEVPG 1201

 Score = 32.7 bits (73), Expect = 0.70
 Identities = 28/110 (25%), Positives = 41/110 (37%), Gaps = 16/110 (14%)
 Frame = +2

Query: 209  PFCEDTGMYKPVQCVGAA--CWCVEESGDEIEGYITGIEESYGK---TCNCAKDKLEYSQ 373
            P C   G ++PVQC      CWCV+  G+ I G +        +    C  ++     S 
Sbjct: 1030 PQCNMIGGWEPVQCHAGTGQCWCVDGRGEFIPGSLMSRSSQMPQCPTNCELSRASGLISA 1089

Query: 374  RKIVGRTFR----------CDHLGNYEKVQCHGSICYCAD-LSGNKIPTS 490
             K  G              C   G Y + Q  G+  +C D  SG  +P +
Sbjct: 1090 WKQAGPQRNPGPGDLFIPVCLQTGEYVRKQTSGTGTWCVDPASGEGMPVN 1139

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 12/30 (40%), Positives = 18/30 (60%), Gaps = 1/30 (3%)
 Frame = +2

Query: 398 RCDHLGNYEKVQCHGS-ICYCADLSGNKIP 484
           RC   G+Y+ VQC    +C+C D  G ++P
Sbjct: 319 RCHRDGHYQTVQCQTEGMCWCVDAQGREVP 348

>sp|P01267|THYG_BOVIN Thyroglobulin precursor
          Length = 2769

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 31/97 (31%), Positives = 41/97 (42%), Gaps = 5/97 (5%)
 Frame = +2

Query: 209 PFCEDTGMYKPVQCVGAACWCVEESGDEIEG-YITGIEESYGKTCNCAKDKLE--YSQRK 379
           P C   G Y+ VQC    CWCV+  G E+ G  + G        C   + +++     + 
Sbjct: 617 PACTAEGSYEEVQCFAGDCWCVDAQGRELAGSRVRGGRPRCPTECEKQRARMQSLLGSQP 676

Query: 380 IVGRTF--RCDHLGNYEKVQCHGSICYCADLSGNKIP 484
                F   C   GN+  VQC  S CYC D  G  IP
Sbjct: 677 AGSSLFVPACTSKGNFLPVQCFNSECYCVDTEGQPIP 713

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 8/99 (8%)
 Frame = +2

Query: 209 PFCEDTGMYKPVQCV--GAACWCVEESGDEIEG-YITGIEESYGKTCNCAKDKL---EYS 370
           P C + G ++ VQC   GA+CWCV+  G E+ G    G   +    C   K ++    Y 
Sbjct: 50  PQCAEDGSFQTVQCGKDGASCWCVDADGREVPGSRQPGRPAACLSFCQLQKQQILLSSYI 109

Query: 371 QRKIVGRTFRCDHLGNYEKVQC--HGSICYCADLSGNKI 481
                    +C   G+Y  VQC      C+C D  G ++
Sbjct: 110 NSTATSYLPQCQDSGDYSPVQCDLRRRQCWCVDAEGMEV 148

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 10/102 (9%)
 Frame = +2

Query: 161 LDARRLIKSGAVDVT----FPFCEDTGMYKPVQCV--GAACWCVEESGDEIEGYITGIEE 322
           L  ++++ S  ++ T     P C+D+G Y PVQC      CWCV+  G E+ G       
Sbjct: 98  LQKQQILLSSYINSTATSYLPQCQDSGDYSPVQCDLRRRQCWCVDAEGMEVYG-----TR 152

Query: 323 SYGKTCNCAKDKLEYSQRKIVGRTFR----CDHLGNYEKVQC 436
             G+   C +     ++R + G   R    C   G +  VQC
Sbjct: 153 QQGRPARCPRSCEIRNRRLLHGVGDRSPPQCSPDGAFRPVQC 194

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 21/58 (36%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
 Frame = +2

Query: 209 PFCEDTGMYKPVQCV-GAACWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEYSQRK 379
           P C   G Y+  QC  G  CWCV+  G EI G         G+  +CA+D+   S+R+
Sbjct: 317 PSCHPDGEYQAAQCQQGGPCWCVDSRGQEIPG-----TRQRGEPPSCAEDQSCPSERR 369

 Score = 37.4 bits (85), Expect = 0.028
 Identities = 25/96 (26%), Positives = 36/96 (37%), Gaps = 18/96 (18%)
 Frame = +2

Query: 209 PFCEDTGMYKPVQCVGAACWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEYSQRKIVG 388
           P C   G + PVQC  + C+CV+  G      I G   + G+   C       ++R  +G
Sbjct: 684 PACTSKGNFLPVQCFNSECYCVDTEGQP----IPGTRSALGEPKKCPSPCQLQAERAFLG 739

Query: 389 --RTF----------------RCDHLGNYEKVQCHG 442
             RT                 +C   G +  VQC G
Sbjct: 740 TVRTLVSNPSTLPALSSIYIPQCSASGQWSPVQCDG 775

 Score = 37.0 bits (84), Expect = 0.037
 Identities = 15/33 (45%), Positives = 20/33 (60%), Gaps = 2/33 (6%)
 Frame = +2

Query: 398  RCDHLGNYEKVQCHGSI--CYCADLSGNKIPTS 490
            +CD  G +E VQCH +   C+C D  G  +PTS
Sbjct: 1030 QCDAFGGWEPVQCHAATGHCWCVDGKGEYVPTS 1062

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
 Frame = +2

Query: 209  PFCE-DTGMYKPVQCVGA--ACWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEYSQRK 379
            P C  + G + PVQC  A  +CWCV  SG+E+ G  T +  S    C   +  L +S   
Sbjct: 1167 PACRAEDGGFSPVQCDPAQGSCWCVLGSGEEVPG--TRVAGSQ-PACESPQCPLPFSVAD 1223

Query: 380  IVGRTFRCD 406
            + G    C+
Sbjct: 1224 VAGGAILCE 1232

 Score = 34.3 bits (77), Expect = 0.24
 Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 4/100 (4%)
 Frame = +2

Query: 197  DVTFPFCEDTGMYKPVQCVGAACWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEYSQR 376
            D+  P C +TG +  +Q   A  WCV+ +  E     T         C   +  +  S+R
Sbjct: 1102 DLFIPTCLETGEFARLQASEAGTWCVDPASGEGVPPGTNSSAQCPSLCEVLQSGVP-SRR 1160

Query: 377  KIVGRTFRC-DHLGNYEKVQC---HGSICYCADLSGNKIP 484
               G +  C    G +  VQC    GS C+C   SG ++P
Sbjct: 1161 TSPGYSPACRAEDGGFSPVQCDPAQGS-CWCVLGSGEEVP 1199

 Score = 33.1 bits (74), Expect = 0.53
 Identities = 14/36 (38%), Positives = 21/36 (58%), Gaps = 2/36 (5%)
 Frame = +2

Query: 209  PFCEDTGMYKPVQCVGAA--CWCVEESGDEIEGYIT 310
            P C+  G ++PVQC  A   CWCV+  G+ +   +T
Sbjct: 1029 PQCDAFGGWEPVQCHAATGHCWCVDGKGEYVPTSLT 1064

 Score = 32.3 bits (72), Expect = 0.91
 Identities = 12/30 (40%), Positives = 17/30 (56%)
 Frame = +2

Query: 401 CDHLGNYEKVQCHGSICYCADLSGNKIPTS 490
           C   G+YE+VQC    C+C D  G ++  S
Sbjct: 619 CTAEGSYEEVQCFAGDCWCVDAQGRELAGS 648

>sp|P01266|THYG_HUMAN Thyroglobulin precursor
          Length = 2768

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 5/97 (5%)
 Frame = +2

Query: 209 PFCEDTGMYKPVQCVGAACWCVEESGDEIEG-YITGIEESYGKTCNCAKDKLE-YSQRKI 382
           P C   G Y+ VQC    CWCV   G E+ G  + G +      C   + +++     + 
Sbjct: 618 PSCTTEGSYEDVQCFSGECWCVNSWGKELPGSRVRGGQPRCPTDCEKQRARMQSLMGSQP 677

Query: 383 VGRTF---RCDHLGNYEKVQCHGSICYCADLSGNKIP 484
            G T     C   G++  VQC  S CYC D  G  IP
Sbjct: 678 AGSTLFVPACTSEGHFLPVQCFNSECYCVDAEGQAIP 714

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 4/101 (3%)
 Frame = +2

Query: 209  PFCE-DTGMYKPVQCVGA--ACWCVEESGDEIEG-YITGIEESYGKTCNCAKDKLEYSQR 376
            P C  + G + PVQC  A  +CWCV +SG+E+ G  +TG + +    C   +  L ++  
Sbjct: 1167 PACRAEDGGFSPVQCDQAQGSCWCVMDSGEEVPGTRVTGGQPA----CESPRCPLPFNAS 1222

Query: 377  KIVGRTFRCDHLGNYEKVQCHGSICYCADLSGNKIPTSPYV 499
            ++VG T  C+ +              C   S +  P  P +
Sbjct: 1223 EVVGGTILCETISGPTGSAMQQCQLLCRQGSWSVFPPGPLI 1263

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 10/102 (9%)
 Frame = +2

Query: 161 LDARRLIKSGAVDVT----FPFCEDTGMYKPVQC--VGAACWCVEESGDEIEGYITGIEE 322
           L  ++++ SG ++ T     P C+D+G Y PVQC      CWCV+  G E+ G       
Sbjct: 98  LQKQQILLSGYINSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYG-----TR 152

Query: 323 SYGKTCNCAKDKLEYSQRKIVG----RTFRCDHLGNYEKVQC 436
             G+   C +     ++R + G       +C   G +  VQC
Sbjct: 153 QLGRPKRCPRSCEIRNRRLLHGVGDKSPPQCSAEGEFMPVQC 194

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 38/131 (29%), Positives = 53/131 (40%), Gaps = 5/131 (3%)
 Frame = +2

Query: 107  CDEVCKEDNNAPNCFKRHLDARRLIKSGAVDVTFPFCEDTGMYKPVQCVGAACWCVE-ES 283
            C   C E +           AR        D+  P C +TG Y  +Q  GA  WCV+  S
Sbjct: 1073 CPTTC-EKSRTSGLLSSWKQARSQENPSPKDLFVPACLETGEYARLQASGAGTWCVDPAS 1131

Query: 284  GDEIEGYITGIEESYGKTCNCAKDKLEYSQRKIVGRTFRC-DHLGNYEKVQC---HGSIC 451
            G+E+    +   +     CN  K  +  S+R   G    C    G +  VQC    GS C
Sbjct: 1132 GEELRPGSSSSAQC-PSLCNVLKSGV-LSRRVSPGYVPACRAEDGGFSPVQCDQAQGS-C 1188

Query: 452  YCADLSGNKIP 484
            +C   SG ++P
Sbjct: 1189 WCVMDSGEEVP 1199

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 32/114 (28%), Positives = 47/114 (41%), Gaps = 15/114 (13%)
 Frame = +2

Query: 167  ARRLIKSGAVDVTFPFCEDTGMYKPVQCVGAA--CWCVEESGDEIEGYITGIEESYGK-- 334
            A  L++SG      P C+  G ++PVQC      CWCV+E G  I G +T       +  
Sbjct: 1018 ASALLRSGPY---MPQCDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGSLTARSLQIPQCP 1074

Query: 335  -TCNCAKD-------KLEYSQRKIVGRTF---RCDHLGNYEKVQCHGSICYCAD 463
             TC  ++        K   SQ     +      C   G Y ++Q  G+  +C D
Sbjct: 1075 TTCEKSRTSGLLSSWKQARSQENPSPKDLFVPACLETGEYARLQASGAGTWCVD 1128

 Score = 37.0 bits (84), Expect = 0.037
 Identities = 29/118 (24%), Positives = 48/118 (40%), Gaps = 18/118 (15%)
 Frame = +2

Query: 143  NCFKRHLDARRLIKSGAVDVTF--PFCEDTGMYKPVQCVGAACWCVEESGDEIEGYITGI 316
            +C K+    + L+ S     T   P C   G + PVQC  + C+CV+  G  I G  + I
Sbjct: 661  DCEKQRARMQSLMGSQPAGSTLFVPACTSEGHFLPVQCFNSECYCVDAEGQAIPGTRSAI 720

Query: 317  --------------EESYGKTCNCAKDKLEYSQRKIVGRTF--RCDHLGNYEKVQCHG 442
                          E+++ +T          S    +  T+  +C   G + +VQC+G
Sbjct: 721  GKPKKCPTPCQLQSEQAFLRTVQALLS--NSSMLPTLSDTYIPQCSTDGQWRQVQCNG 776

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
 Frame = +2

Query: 209 PFCEDTGMYKPVQC-VGAACWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEYSQRK 379
           P C   G Y+ VQC     CWCV+  G E+ G         G+  +CA+ +   S+R+
Sbjct: 317 PSCRRNGDYQAVQCQTEGPCWCVDAQGKEMHG-----TRQQGEPPSCAEGQSCASERQ 369

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 15/33 (45%), Positives = 19/33 (57%), Gaps = 2/33 (6%)
 Frame = +2

Query: 398  RCDHLGNYEKVQCHGSI--CYCADLSGNKIPTS 490
            +CD  G++E VQCH     C+C D  G  IP S
Sbjct: 1030 QCDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGS 1062

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
 Frame = +2

Query: 263  CWCVEESGDEIEGYITGIEESYGKTC--NCAKDKLEYSQ 373
            CWCV+E+G E+EG  +  E S   TC  +C + KL   Q
Sbjct: 898  CWCVDEAGQELEGMRS--EPSKLPTCPGSCEEAKLRVLQ 934

 Score = 31.2 bits (69), Expect = 2.0
 Identities = 12/30 (40%), Positives = 17/30 (56%)
 Frame = +2

Query: 401 CDHLGNYEKVQCHGSICYCADLSGNKIPTS 490
           C   G+YE VQC    C+C +  G ++P S
Sbjct: 620 CTTEGSYEDVQCFSGECWCVNSWGKELPGS 649

>sp|O88322|NID2_MOUSE Nidogen-2 precursor (NID-2) (Entactin-2)
          Length = 1403

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 33/114 (28%), Positives = 51/114 (44%), Gaps = 20/114 (17%)
 Frame = +2

Query: 200  VTFPFCEDTGMYKPVQCVGAA--CWCVEESGDEIEGYIT---------GIEESYGKTCNC 346
            +  P C+D G + P+QC G+   CWCV+ +G E+ G  T         G      +    
Sbjct: 986  IHIPQCDDQGNFVPLQCHGSTGFCWCVDRNGHEVPGTQTPPGSTPPHCGPPPEPTQRPRT 1045

Query: 347  AKDKLEYSQRKIVGRTFR-------CDHLGNYEKVQCHG--SICYCADLSGNKI 481
              ++   S  +  G T R       CD LG++  +QCHG    C+C D  G ++
Sbjct: 1046 VCERWRESLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREL 1099

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 2/37 (5%)
 Frame = +2

Query: 197  DVTFPFCEDTGMYKPVQCVGAA--CWCVEESGDEIEG 301
            D   P C+D G + P+QC G +  CWCV++ G E++G
Sbjct: 1065 DQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGRELQG 1101

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 14/31 (45%), Positives = 22/31 (70%), Gaps = 2/31 (6%)
 Frame = +2

Query: 398  RCDHLGNYEKVQCHGS--ICYCADLSGNKIP 484
            +CD  GN+  +QCHGS   C+C D +G+++P
Sbjct: 990  QCDDQGNFVPLQCHGSTGFCWCVDRNGHEVP 1020

>sp|Q14112|NID2_HUMAN Nidogen-2 precursor (NID-2) (Osteonidogen)
          Length = 1375

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 35/115 (30%), Positives = 50/115 (43%), Gaps = 24/115 (20%)
 Frame = +2

Query: 209  PFCEDTGMYKPVQCVGAA--CWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEYSQR-- 376
            P C++ G + P+QC G+   CWCV+  G E+ G  T      G T        E +QR  
Sbjct: 961  PQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQT----PPGSTPPHCGPSPEPTQRPP 1016

Query: 377  -----------KIVGRTFR-------CDHLGNYEKVQCHG--SICYCADLSGNKI 481
                       +  G T R       CD LG++  +QCHG    C+C D  G ++
Sbjct: 1017 TICERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREV 1071

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 2/37 (5%)
 Frame = +2

Query: 197  DVTFPFCEDTGMYKPVQCVGAA--CWCVEESGDEIEG 301
            D   P C+D G + P+QC G +  CWCV++ G E++G
Sbjct: 1037 DQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQG 1073

 Score = 37.7 bits (86), Expect = 0.022
 Identities = 14/31 (45%), Positives = 21/31 (67%), Gaps = 2/31 (6%)
 Frame = +2

Query: 398  RCDHLGNYEKVQCHGS--ICYCADLSGNKIP 484
            +CD  GN+  +QCHGS   C+C D  G+++P
Sbjct: 962  QCDEQGNFLPLQCHGSTGFCWCVDPDGHEVP 992

>sp|P81439|EQST_ACTEQ Equistatin
          Length = 199

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 38/111 (34%), Positives = 53/111 (47%), Gaps = 12/111 (10%)
 Frame = +2

Query: 185 SGAVDVTFPFCEDTGMYKPVQCVGAA--CWCVEESGDEIEGYITGIEESYGKTCNCAKDK 358
           SG +    P C++TG ++  QC G+   CWCV+E G EI G  T I  S    C+  K  
Sbjct: 14  SGLIGAYVPQCKETGEFEEKQCWGSTGYCWCVDEDGKEILG--TKIRGS--PDCSRRKAA 69

Query: 359 L---EYSQRKIVG-----RTFRCDHLGNYEKVQCHGS--ICYCADLSGNKI 481
           L   +  Q  IV          C   G++++VQC  S   CYC D  G ++
Sbjct: 70  LTLCQMMQAIIVNVPGWCGPPSCKADGSFDEVQCCASNGECYCVDKKGKEL 120

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 7/101 (6%)
 Frame = +2

Query: 209 PFCEDTGMYKPVQCVGA--ACWCVEESGDEIEGYITGIEESYGKTCN-CAKDKLEYSQRK 379
           P C+  G +  VQC  +   C+CV++ G E+EG       S  +  + C + +L+     
Sbjct: 90  PSCKADGSFDEVQCCASNGECYCVDKKGKELEGTRQKGRPSCERHLSPCEEARLQAHSNS 149

Query: 380 IVGRTF--RCDHLGNYEKVQCHGS--ICYCADLSGNKIPTS 490
           +    F  +C   G+Y  VQC  S   C+C D  G K+P S
Sbjct: 150 LRVGMFVPQCLEDGSYNPVQCWPSTGYCWCVDEGGVKVPGS 190

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 13/103 (12%)
 Frame = +2

Query: 32  TCIFSSKLEEFDVCGNNDQCNVGLICDEVCKE-----DNNAPNCFKRHL----DARRLIK 184
           +C      +E   C +N +C      D+  KE         P+C +RHL    +AR    
Sbjct: 91  SCKADGSFDEVQCCASNGEC---YCVDKKGKELEGTRQKGRPSC-ERHLSPCEEARLQAH 146

Query: 185 SGAVDVTF--PFCEDTGMYKPVQCVGAA--CWCVEESGDEIEG 301
           S ++ V    P C + G Y PVQC  +   CWCV+E G ++ G
Sbjct: 147 SNSLRVGMFVPQCLEDGSYNPVQCWPSTGYCWCVDEGGVKVPG 189

>sp|Q9BQ16|TICN3_HUMAN Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like
           domains proteoglycan 3)
          Length = 436

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 16/33 (48%), Positives = 22/33 (66%), Gaps = 2/33 (6%)
 Frame = +2

Query: 209 PFCEDTGMYKPVQCVGAA--CWCVEESGDEIEG 301
           P C++ G YKP QC G+   CWCV+  G+E+ G
Sbjct: 339 PLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMG 371

 Score = 37.0 bits (84), Expect = 0.037
 Identities = 18/49 (36%), Positives = 29/49 (59%), Gaps = 3/49 (6%)
 Frame = +2

Query: 374 RKIVGRTFR-CDHLGNYEKVQCHGSI--CYCADLSGNKIPTSPYVDIAN 511
           +K++G+    CD  G Y+  QCHGS+  C+C D  GN++  S    +A+
Sbjct: 331 KKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMGSRINGVAD 379

>sp|Q8BKV0|TICN3_MOUSE Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like
           domains proteoglycan 3)
          Length = 436

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 16/33 (48%), Positives = 22/33 (66%), Gaps = 2/33 (6%)
 Frame = +2

Query: 209 PFCEDTGMYKPVQCVGAA--CWCVEESGDEIEG 301
           P C++ G YKP QC G+   CWCV+  G+E+ G
Sbjct: 339 PLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVVG 371

 Score = 37.0 bits (84), Expect = 0.037
 Identities = 18/49 (36%), Positives = 29/49 (59%), Gaps = 3/49 (6%)
 Frame = +2

Query: 374 RKIVGRTFR-CDHLGNYEKVQCHGSI--CYCADLSGNKIPTSPYVDIAN 511
           +K++G+    CD  G Y+  QCHGS+  C+C D  GN++  S    +A+
Sbjct: 331 KKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVVGSRINGVAD 379

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,334,839
Number of Sequences: 369166
Number of extensions: 1405467
Number of successful extensions: 3785
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3480
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3714
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4455160255
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

1. Dr_sW_026_A20
2. Dr_sW_026_K20
3. Dr_sW_024_M11
4. Dr_sW_012_O19
5. Dr_sW_018_C13
6. Dr_sW_001_H01
7. Dr_sW_028_H06
8. Dr_sW_004_C09
9. Dr_sW_003_A17
10. Dr_sW_001_L15
11. Dr_sW_004_F05
12. Dr_sW_023_L23
13. Dr_sW_008_A16