Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_M11
(569 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P31226|SAX_RANCA Saxiphilin precursor (SAX) 58 2e-08
sp|P06882|THYG_RAT Thyroglobulin precursor 54 2e-07
sp|O08710|THYG_MOUSE Thyroglobulin precursor 53 5e-07
sp|P01267|THYG_BOVIN Thyroglobulin precursor 52 1e-06
sp|O88322|NID2_MOUSE Nidogen-2 precursor (NID-2) (Entactin-2) 51 2e-06
sp|P01266|THYG_HUMAN Thyroglobulin precursor 51 2e-06
sp|P81439|EQST_ACTEQ Equistatin 48 2e-05
sp|Q14112|NID2_HUMAN Nidogen-2 precursor (NID-2) (Osteonido... 48 2e-05
sp|Q9BQ16|TICN3_HUMAN Testican-3 precursor (SPARC/osteonect... 43 5e-04
sp|Q8BKV0|TICN3_MOUSE Testican-3 precursor (SPARC/osteonect... 43 5e-04
>sp|P31226|SAX_RANCA Saxiphilin precursor (SAX)
Length = 844
Score = 57.8 bits (138), Expect = 2e-08
Identities = 43/148 (29%), Positives = 65/148 (43%), Gaps = 11/148 (7%)
Frame = +1
Query: 64 NNDQCNVGLICDEVCKEDNNAPNCFKRHLDARRLIKSGAVDVTFPFCEDTGMYKPVQCVG 243
+ D N+ I E + + C K A + + P C++ G Y+P QC G
Sbjct: 87 SKDPYNLKPIIAEPYSSNRDLQKCLKERQQA---LAKKMIGHYIPQCDEKGNYQPQQCHG 143
Query: 244 AA--CWCVEESGDEIEGYITGIEESYGKTCN------CAKDKLEY--SQRKIVGRTF-RC 390
+ CWCV G++I G T ++ TC C K++ K++GR +C
Sbjct: 144 STGHCWCVNAMGEKISGTNTPPGQTRA-TCERHELPKCLKERQVALGGDEKVLGRFVPQC 202
Query: 391 DHLGNYEKVQCHGSICYCADLSGINTDI 474
D GNYE Q HGS Y ++ I +I
Sbjct: 203 DEKGNYEPQQFHGSTGYSWCVNAIGEEI 230
Score = 32.0 bits (71), Expect = 1.1
Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 5/64 (7%)
Frame = +1
Query: 112 EDNNAPNCFKRHLDARRLIKSGAVDVT---FPFCEDTGMYKPVQCVGAA--CWCVEESGD 276
E + P C K R++ G V P C++ G Y+P Q G+ WCV G+
Sbjct: 173 ERHELPKCLKE----RQVALGGDEKVLGRFVPQCDEKGNYEPQQFHGSTGYSWCVNAIGE 228
Query: 277 EIEG 288
EI G
Sbjct: 229 EIAG 232
>sp|P06882|THYG_RAT Thyroglobulin precursor
Length = 2768
Score = 54.3 bits (129), Expect = 2e-07
Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Frame = +1
Query: 196 PFCEDTGMYKPVQCVGAACWCVEESGDEIEG-YITGIEESYGKTCNCAKDKLE-YSQRKI 369
P C G Y+ +QC CWCV G E+EG ++G C + +++ + +
Sbjct: 618 PSCTAEGSYEDIQCYAGECWCVNSQGKEVEGSRVSGGHPRCPTKCEKQRAQMQNLAGAQP 677
Query: 370 VGRTF---RCDHLGNYEKVQCHGSICYCADLSG 459
G +F C G + VQC S CYC D G
Sbjct: 678 AGSSFFVPTCTSEGYFLPVQCFNSECYCVDAEG 710
Score = 47.8 bits (112), Expect = 2e-05
Identities = 30/106 (28%), Positives = 43/106 (40%), Gaps = 13/106 (12%)
Frame = +1
Query: 184 DVTFPFCEDTGMYKPVQCV--GAACWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEYS 357
D P C + G ++ VQC G +CWCV+ G E+ G G+ C +
Sbjct: 47 DEYVPQCSEDGSFQTVQCQNDGQSCWCVDSDGTEVPG-----SRQLGRPTACLSFCQLHK 101
Query: 358 QRKIVGRTF---------RCDHLGNYEKVQC--HGSICYCADLSGI 462
QR ++ +C GNY VQC C+C D G+
Sbjct: 102 QRILLSSYINSTDALYLPQCQDSGNYAPVQCDLQQVQCWCVDTEGM 147
Score = 45.1 bits (105), Expect = 1e-04
Identities = 31/102 (30%), Positives = 46/102 (45%), Gaps = 10/102 (9%)
Frame = +1
Query: 148 LDARRLIKSGAVDVT----FPFCEDTGMYKPVQC--VGAACWCVEESGDEIEGYITGIEE 309
L +R++ S ++ T P C+D+G Y PVQC CWCV+ G E+ G
Sbjct: 99 LHKQRILLSSYINSTDALYLPQCQDSGNYAPVQCDLQQVQCWCVDTEGMEVYG-----TR 153
Query: 310 SYGKTCNCAKDKLEYSQRKIVG----RTFRCDHLGNYEKVQC 423
G+ C + S+R + G +CD G + VQC
Sbjct: 154 QQGRPTRCPRSCEIRSRRLLHGVGDKSPPQCDADGEFMPVQC 195
Score = 40.8 bits (94), Expect = 0.002
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 4/99 (4%)
Frame = +1
Query: 175 GAVDVTFPFCEDTGMYKPVQCVGAACWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEY 354
G D+ P C TG Y Q G WCV+ S E T C+ K ++
Sbjct: 1100 GPGDLFTPVCLQTGEYVRQQTSGTGAWCVDPSSGEGVPTNTNSSAQCPGLCDALKSRV-L 1158
Query: 355 SQRKIVGRTFRCDHL-GNYEKVQC---HGSICYCADLSG 459
S++ +G T C+ L G + VQC GS C+C SG
Sbjct: 1159 SRKVGLGYTPVCEALDGGFSPVQCDLAQGS-CWCVLASG 1196
Score = 38.9 bits (89), Expect = 0.009
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Frame = +1
Query: 196 PFCEDTGMYKPVQC-VGAACWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEYSQRK 366
P C G Y+ VQC + CWCV+ G EI G G+ CAKD+ S+R+
Sbjct: 318 PSCHRDGHYQTVQCQMERMCWCVDAQGIEIPG-----TRQQGQPLFCAKDQSCASERQ 370
Score = 36.2 bits (82), Expect = 0.059
Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Frame = +1
Query: 133 CFKRHLDARRLIKSGAVDVTF--PFCEDTGMYKPVQCVGAACWCVEESGDEIEGYITGIE 306
C K+ + L + +F P C G + PVQC + C+CV+ G I G + I
Sbjct: 662 CEKQRAQMQNLAGAQPAGSSFFVPTCTSEGYFLPVQCFNSECYCVDAEGQVIPGTQSTIG 721
Query: 307 E 309
E
Sbjct: 722 E 722
Score = 33.9 bits (76), Expect = 0.29
Identities = 16/34 (47%), Positives = 20/34 (58%), Gaps = 3/34 (8%)
Frame = +1
Query: 196 PFCEDT-GMYKPVQC--VGAACWCVEESGDEIEG 288
P CE G + PVQC +CWCV SG+E+ G
Sbjct: 1168 PVCEALDGGFSPVQCDLAQGSCWCVLASGEEVPG 1201
Score = 33.5 bits (75), Expect = 0.38
Identities = 28/102 (27%), Positives = 39/102 (38%), Gaps = 15/102 (14%)
Frame = +1
Query: 196 PFCEDTGMYKPVQCVGAA--CWCVEESGDEIEGYI-----------TGIEESYGKTCNCA 336
P C G ++PVQC CWCV+ G+ I G + T E S A
Sbjct: 1030 PQCNTIGGWEPVQCHPGTGQCWCVDGWGELIPGSLMARSSQMPQCPTSCELSRANGLISA 1089
Query: 337 KDKLEYSQRKIVGRTFR--CDHLGNYEKVQCHGSICYCADLS 456
+ + + G F C G Y + Q G+ +C D S
Sbjct: 1090 WKQAGHQRNPGPGDLFTPVCLQTGEYVRQQTSGTGAWCVDPS 1131
Score = 29.3 bits (64), Expect = 7.2
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Frame = +1
Query: 319 KTCNCAKDKLEYSQRKIVGRTFRCDHLGNYEKVQCH--GSICYCADLSGINTDIPVCR 486
+ C ++K Q + V + C G+++ VQC G C+C D G T++P R
Sbjct: 33 RPCELQREKAFLKQDEYVPQ---CSEDGSFQTVQCQNDGQSCWCVDSDG--TEVPGSR 85
Score = 28.9 bits (63), Expect = 9.4
Identities = 8/14 (57%), Positives = 13/14 (92%)
Frame = +1
Query: 247 ACWCVEESGDEIEG 288
+CWCV+E+G E++G
Sbjct: 898 SCWCVDEAGQELDG 911
>sp|O08710|THYG_MOUSE Thyroglobulin precursor
Length = 2766
Score = 53.1 bits (126), Expect = 5e-07
Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Frame = +1
Query: 196 PFCEDTGMYKPVQCVGAACWCVEESGDEIEG-YITGIEESYGKTCNCAKDKLE-YSQRKI 369
P C G Y+ +QC CWCV+ G E++G + G C + +++ + +
Sbjct: 618 PSCTAGGSYEDIQCYAGECWCVDSRGKELDGSRVRGGRPRCPTKCEKQRAQMQSLASAQP 677
Query: 370 VGRTF---RCDHLGNYEKVQCHGSICYCADLSG 459
G +F C G + VQC S CYC D G
Sbjct: 678 AGSSFFVPTCTREGYFLPVQCFNSECYCVDTEG 710
Score = 48.9 bits (115), Expect = 9e-06
Identities = 30/102 (29%), Positives = 43/102 (42%), Gaps = 13/102 (12%)
Frame = +1
Query: 196 PFCEDTGMYKPVQCV--GAACWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEYSQRKI 369
P C + G ++ VQC G +CWCV+ G E+ G G+ C + QR +
Sbjct: 51 PQCSEDGSFQTVQCQNDGQSCWCVDSDGREVPG-----SRQLGRPTVCLSFCQLHKQRIL 105
Query: 370 VGRTF---------RCDHLGNYEKVQC--HGSICYCADLSGI 462
+G +C GNY VQC C+C D G+
Sbjct: 106 LGSYINSTDALYLPQCQDSGNYAPVQCDLQRVQCWCVDTEGM 147
Score = 40.4 bits (93), Expect = 0.003
Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 6/82 (7%)
Frame = +1
Query: 196 PFCEDTGMYKPVQC--VGAACWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEYSQRKI 369
P C+D+G Y PVQC CWCV+ G E+ G G+ C + ++R +
Sbjct: 119 PQCQDSGNYAPVQCDLQRVQCWCVDTEGMEVYG-----TRQQGRPTRCPRSCEIRNRRLL 173
Query: 370 VGRTFR----CDHLGNYEKVQC 423
G R C G + VQC
Sbjct: 174 HGVGDRSPPQCTADGEFMPVQC 195
Score = 36.6 bits (83), Expect = 0.045
Identities = 29/117 (24%), Positives = 47/117 (40%), Gaps = 18/117 (15%)
Frame = +1
Query: 133 CFKRHLDARRLIKSGAVDVTF--PFCEDTGMYKPVQCVGAACWCVEESGDEIEGYITGIE 306
C K+ + L + +F P C G + PVQC + C+CV+ G I G + +
Sbjct: 662 CEKQRAQMQSLASAQPAGSSFFVPTCTREGYFLPVQCFNSECYCVDTEGQVIPGTQSTVG 721
Query: 307 ESYGKTC-NCAKDKLEYSQRKIVGRTF---------------RCDHLGNYEKVQCHG 429
E+ K C + + + E + +VG +C G + VQC G
Sbjct: 722 EA--KQCPSVCQLQAEQAFLGVVGVLLSNSSMVPSISNVYIPQCSASGQWRHVQCDG 776
Score = 35.4 bits (80), Expect = 0.10
Identities = 18/51 (35%), Positives = 24/51 (47%), Gaps = 1/51 (1%)
Frame = +1
Query: 196 PFCEDTGMYKPVQC-VGAACWCVEESGDEIEGYITGIEESYGKTCNCAKDK 345
P C G Y+ VQC CWCV+ G E+ G G+ +CA D+
Sbjct: 318 PRCHRDGHYQTVQCQTEGMCWCVDAQGREVPG-----TRQQGQPPSCAADQ 363
Score = 35.0 bits (79), Expect = 0.13
Identities = 30/99 (30%), Positives = 42/99 (42%), Gaps = 4/99 (4%)
Frame = +1
Query: 175 GAVDVTFPFCEDTGMYKPVQCVGAACWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEY 354
G D+ P C TG Y Q G WCV+ + E T C+ K +
Sbjct: 1100 GPGDLFIPVCLQTGEYVRKQTSGTGTWCVDPASGEGMPVNTNGSAQCPGLCDVLKSR-AL 1158
Query: 355 SQRKIVGRTFRCDHL-GNYEKVQC---HGSICYCADLSG 459
S++ +G + C+ L G + VQC GS C+C SG
Sbjct: 1159 SRKVGLGYSPVCEALDGAFSPVQCDLAQGS-CWCVLGSG 1196
Score = 34.3 bits (77), Expect = 0.22
Identities = 16/34 (47%), Positives = 20/34 (58%), Gaps = 3/34 (8%)
Frame = +1
Query: 196 PFCEDT-GMYKPVQC--VGAACWCVEESGDEIEG 288
P CE G + PVQC +CWCV SG+E+ G
Sbjct: 1168 PVCEALDGAFSPVQCDLAQGSCWCVLGSGEEVPG 1201
Score = 31.6 bits (70), Expect = 1.5
Identities = 14/33 (42%), Positives = 18/33 (54%), Gaps = 2/33 (6%)
Frame = +1
Query: 196 PFCEDTGMYKPVQCVGAA--CWCVEESGDEIEG 288
P C G ++PVQC CWCV+ G+ I G
Sbjct: 1030 PQCNMIGGWEPVQCHAGTGQCWCVDGRGEFIPG 1062
Score = 30.4 bits (67), Expect = 3.2
Identities = 11/28 (39%), Positives = 15/28 (53%)
Frame = +1
Query: 388 CDHLGNYEKVQCHGSICYCADLSGINTD 471
C G+YE +QC+ C+C D G D
Sbjct: 620 CTAGGSYEDIQCYAGECWCVDSRGKELD 647
>sp|P01267|THYG_BOVIN Thyroglobulin precursor
Length = 2769
Score = 51.6 bits (122), Expect = 1e-06
Identities = 29/93 (31%), Positives = 39/93 (41%), Gaps = 5/93 (5%)
Frame = +1
Query: 196 PFCEDTGMYKPVQCVGAACWCVEESGDEIEG-YITGIEESYGKTCNCAKDKLE--YSQRK 366
P C G Y+ VQC CWCV+ G E+ G + G C + +++ +
Sbjct: 617 PACTAEGSYEEVQCFAGDCWCVDAQGRELAGSRVRGGRPRCPTECEKQRARMQSLLGSQP 676
Query: 367 IVGRTF--RCDHLGNYEKVQCHGSICYCADLSG 459
F C GN+ VQC S CYC D G
Sbjct: 677 AGSSLFVPACTSKGNFLPVQCFNSECYCVDTEG 709
Score = 46.2 bits (108), Expect = 6e-05
Identities = 29/97 (29%), Positives = 42/97 (43%), Gaps = 8/97 (8%)
Frame = +1
Query: 196 PFCEDTGMYKPVQCV--GAACWCVEESGDEIEG-YITGIEESYGKTCNCAKDKL---EYS 357
P C + G ++ VQC GA+CWCV+ G E+ G G + C K ++ Y
Sbjct: 50 PQCAEDGSFQTVQCGKDGASCWCVDADGREVPGSRQPGRPAACLSFCQLQKQQILLSSYI 109
Query: 358 QRKIVGRTFRCDHLGNYEKVQC--HGSICYCADLSGI 462
+C G+Y VQC C+C D G+
Sbjct: 110 NSTATSYLPQCQDSGDYSPVQCDLRRRQCWCVDAEGM 146
Score = 40.8 bits (94), Expect = 0.002
Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 10/102 (9%)
Frame = +1
Query: 148 LDARRLIKSGAVDVT----FPFCEDTGMYKPVQCV--GAACWCVEESGDEIEGYITGIEE 309
L ++++ S ++ T P C+D+G Y PVQC CWCV+ G E+ G
Sbjct: 98 LQKQQILLSSYINSTATSYLPQCQDSGDYSPVQCDLRRRQCWCVDAEGMEVYG-----TR 152
Query: 310 SYGKTCNCAKDKLEYSQRKIVGRTFR----CDHLGNYEKVQC 423
G+ C + ++R + G R C G + VQC
Sbjct: 153 QQGRPARCPRSCEIRNRRLLHGVGDRSPPQCSPDGAFRPVQC 194
Score = 40.0 bits (92), Expect = 0.004
Identities = 21/58 (36%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Frame = +1
Query: 196 PFCEDTGMYKPVQCV-GAACWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEYSQRK 366
P C G Y+ QC G CWCV+ G EI G G+ +CA+D+ S+R+
Sbjct: 317 PSCHPDGEYQAAQCQQGGPCWCVDSRGQEIPG-----TRQRGEPPSCAEDQSCPSERR 369
Score = 37.4 bits (85), Expect = 0.026
Identities = 25/96 (26%), Positives = 36/96 (37%), Gaps = 18/96 (18%)
Frame = +1
Query: 196 PFCEDTGMYKPVQCVGAACWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEYSQRKIVG 375
P C G + PVQC + C+CV+ G I G + G+ C ++R +G
Sbjct: 684 PACTSKGNFLPVQCFNSECYCVDTEGQP----IPGTRSALGEPKKCPSPCQLQAERAFLG 739
Query: 376 --RTF----------------RCDHLGNYEKVQCHG 429
RT +C G + VQC G
Sbjct: 740 TVRTLVSNPSTLPALSSIYIPQCSASGQWSPVQCDG 775
Score = 33.1 bits (74), Expect = 0.50
Identities = 14/36 (38%), Positives = 21/36 (58%), Gaps = 2/36 (5%)
Frame = +1
Query: 196 PFCEDTGMYKPVQCVGAA--CWCVEESGDEIEGYIT 297
P C+ G ++PVQC A CWCV+ G+ + +T
Sbjct: 1029 PQCDAFGGWEPVQCHAATGHCWCVDGKGEYVPTSLT 1064
Score = 30.8 bits (68), Expect = 2.5
Identities = 25/102 (24%), Positives = 40/102 (39%), Gaps = 1/102 (0%)
Frame = +1
Query: 184 DVTFPFCEDTGMYKPVQCVGAACWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEYSQR 363
D+ P C +TG + +Q A WCV+ + E T C + + S+R
Sbjct: 1102 DLFIPTCLETGEFARLQASEAGTWCVDPASGEGVPPGTNSSAQCPSLCEVLQSGVP-SRR 1160
Query: 364 KIVGRTFRC-DHLGNYEKVQCHGSICYCADLSGINTDIPVCR 486
G + C G + VQC + C + G ++P R
Sbjct: 1161 TSPGYSPACRAEDGGFSPVQCDPAQGSCWCVLGSGEEVPGTR 1202
Score = 30.4 bits (67), Expect = 3.2
Identities = 12/27 (44%), Positives = 16/27 (59%), Gaps = 2/27 (7%)
Frame = +1
Query: 385 RCDHLGNYEKVQCHGSI--CYCADLSG 459
+CD G +E VQCH + C+C D G
Sbjct: 1030 QCDAFGGWEPVQCHAATGHCWCVDGKG 1056
>sp|O88322|NID2_MOUSE Nidogen-2 precursor (NID-2) (Entactin-2)
Length = 1403
Score = 51.2 bits (121), Expect = 2e-06
Identities = 33/111 (29%), Positives = 49/111 (44%), Gaps = 20/111 (18%)
Frame = +1
Query: 187 VTFPFCEDTGMYKPVQCVGAA--CWCVEESGDEIEGYIT---------GIEESYGKTCNC 333
+ P C+D G + P+QC G+ CWCV+ +G E+ G T G +
Sbjct: 986 IHIPQCDDQGNFVPLQCHGSTGFCWCVDRNGHEVPGTQTPPGSTPPHCGPPPEPTQRPRT 1045
Query: 334 AKDKLEYSQRKIVGRTFR-------CDHLGNYEKVQCHG--SICYCADLSG 459
++ S + G T R CD LG++ +QCHG C+C D G
Sbjct: 1046 VCERWRESLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDG 1096
Score = 40.0 bits (92), Expect = 0.004
Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 2/37 (5%)
Frame = +1
Query: 184 DVTFPFCEDTGMYKPVQCVGAA--CWCVEESGDEIEG 288
D P C+D G + P+QC G + CWCV++ G E++G
Sbjct: 1065 DQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGRELQG 1101
>sp|P01266|THYG_HUMAN Thyroglobulin precursor
Length = 2768
Score = 51.2 bits (121), Expect = 2e-06
Identities = 29/93 (31%), Positives = 40/93 (43%), Gaps = 5/93 (5%)
Frame = +1
Query: 196 PFCEDTGMYKPVQCVGAACWCVEESGDEIEG-YITGIEESYGKTCNCAKDKLE-YSQRKI 369
P C G Y+ VQC CWCV G E+ G + G + C + +++ +
Sbjct: 618 PSCTTEGSYEDVQCFSGECWCVNSWGKELPGSRVRGGQPRCPTDCEKQRARMQSLMGSQP 677
Query: 370 VGRTF---RCDHLGNYEKVQCHGSICYCADLSG 459
G T C G++ VQC S CYC D G
Sbjct: 678 AGSTLFVPACTSEGHFLPVQCFNSECYCVDAEG 710
Score = 42.4 bits (98), Expect = 8e-04
Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 4/70 (5%)
Frame = +1
Query: 196 PFCE-DTGMYKPVQCVGA--ACWCVEESGDEIEG-YITGIEESYGKTCNCAKDKLEYSQR 363
P C + G + PVQC A +CWCV +SG+E+ G +TG + + C + L ++
Sbjct: 1167 PACRAEDGGFSPVQCDQAQGSCWCVMDSGEEVPGTRVTGGQPA----CESPRCPLPFNAS 1222
Query: 364 KIVGRTFRCD 393
++VG T C+
Sbjct: 1223 EVVGGTILCE 1232
Score = 42.0 bits (97), Expect = 0.001
Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 10/102 (9%)
Frame = +1
Query: 148 LDARRLIKSGAVDVT----FPFCEDTGMYKPVQC--VGAACWCVEESGDEIEGYITGIEE 309
L ++++ SG ++ T P C+D+G Y PVQC CWCV+ G E+ G
Sbjct: 98 LQKQQILLSGYINSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYG-----TR 152
Query: 310 SYGKTCNCAKDKLEYSQRKIVG----RTFRCDHLGNYEKVQC 423
G+ C + ++R + G +C G + VQC
Sbjct: 153 QLGRPKRCPRSCEIRNRRLLHGVGDKSPPQCSAEGEFMPVQC 194
Score = 39.7 bits (91), Expect = 0.005
Identities = 32/114 (28%), Positives = 47/114 (41%), Gaps = 15/114 (13%)
Frame = +1
Query: 154 ARRLIKSGAVDVTFPFCEDTGMYKPVQCVGAA--CWCVEESGDEIEGYITGIEESYGK-- 321
A L++SG P C+ G ++PVQC CWCV+E G I G +T +
Sbjct: 1018 ASALLRSGPY---MPQCDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGSLTARSLQIPQCP 1074
Query: 322 -TCNCAKD-------KLEYSQRKIVGRTF---RCDHLGNYEKVQCHGSICYCAD 450
TC ++ K SQ + C G Y ++Q G+ +C D
Sbjct: 1075 TTCEKSRTSGLLSSWKQARSQENPSPKDLFVPACLETGEYARLQASGAGTWCVD 1128
Score = 37.0 bits (84), Expect = 0.035
Identities = 29/118 (24%), Positives = 48/118 (40%), Gaps = 18/118 (15%)
Frame = +1
Query: 130 NCFKRHLDARRLIKSGAVDVTF--PFCEDTGMYKPVQCVGAACWCVEESGDEIEGYITGI 303
+C K+ + L+ S T P C G + PVQC + C+CV+ G I G + I
Sbjct: 661 DCEKQRARMQSLMGSQPAGSTLFVPACTSEGHFLPVQCFNSECYCVDAEGQAIPGTRSAI 720
Query: 304 --------------EESYGKTCNCAKDKLEYSQRKIVGRTF--RCDHLGNYEKVQCHG 429
E+++ +T S + T+ +C G + +VQC+G
Sbjct: 721 GKPKKCPTPCQLQSEQAFLRTVQALLS--NSSMLPTLSDTYIPQCSTDGQWRQVQCNG 776
Score = 37.0 bits (84), Expect = 0.035
Identities = 37/127 (29%), Positives = 50/127 (39%), Gaps = 5/127 (3%)
Frame = +1
Query: 94 CDEVCKEDNNAPNCFKRHLDARRLIKSGAVDVTFPFCEDTGMYKPVQCVGAACWCVE-ES 270
C C E + AR D+ P C +TG Y +Q GA WCV+ S
Sbjct: 1073 CPTTC-EKSRTSGLLSSWKQARSQENPSPKDLFVPACLETGEYARLQASGAGTWCVDPAS 1131
Query: 271 GDEIEGYITGIEESYGKTCNCAKDKLEYSQRKIVGRTFRC-DHLGNYEKVQC---HGSIC 438
G+E+ + + CN K + S+R G C G + VQC GS C
Sbjct: 1132 GEELRPGSSSSAQC-PSLCNVLKSGV-LSRRVSPGYVPACRAEDGGFSPVQCDQAQGS-C 1188
Query: 439 YCADLSG 459
+C SG
Sbjct: 1189 WCVMDSG 1195
Score = 35.4 bits (80), Expect = 0.10
Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Frame = +1
Query: 196 PFCEDTGMYKPVQC-VGAACWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEYSQRK 366
P C G Y+ VQC CWCV+ G E+ G G+ +CA+ + S+R+
Sbjct: 317 PSCRRNGDYQAVQCQTEGPCWCVDAQGKEMHG-----TRQQGEPPSCAEGQSCASERQ 369
Score = 31.6 bits (70), Expect = 1.5
Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
Frame = +1
Query: 250 CWCVEESGDEIEGYITGIEESYGKTC--NCAKDKLEYSQ 360
CWCV+E+G E+EG + E S TC +C + KL Q
Sbjct: 898 CWCVDEAGQELEGMRS--EPSKLPTCPGSCEEAKLRVLQ 934
Score = 30.8 bits (68), Expect = 2.5
Identities = 12/27 (44%), Positives = 16/27 (59%), Gaps = 2/27 (7%)
Frame = +1
Query: 385 RCDHLGNYEKVQCHGSI--CYCADLSG 459
+CD G++E VQCH C+C D G
Sbjct: 1030 QCDAFGSWEPVQCHAGTGHCWCVDEKG 1056
>sp|P81439|EQST_ACTEQ Equistatin
Length = 199
Score = 48.1 bits (113), Expect = 2e-05
Identities = 38/108 (35%), Positives = 51/108 (47%), Gaps = 12/108 (11%)
Frame = +1
Query: 172 SGAVDVTFPFCEDTGMYKPVQCVGAA--CWCVEESGDEIEGYITGIEESYGKTCNCAKDK 345
SG + P C++TG ++ QC G+ CWCV+E G EI G T I S C+ K
Sbjct: 14 SGLIGAYVPQCKETGEFEEKQCWGSTGYCWCVDEDGKEILG--TKIRGS--PDCSRRKAA 69
Query: 346 L---EYSQRKIVG-----RTFRCDHLGNYEKVQCHGS--ICYCADLSG 459
L + Q IV C G++++VQC S CYC D G
Sbjct: 70 LTLCQMMQAIIVNVPGWCGPPSCKADGSFDEVQCCASNGECYCVDKKG 117
Score = 44.3 bits (103), Expect = 2e-04
Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 13/103 (12%)
Frame = +1
Query: 19 TCIFSSKLEEFDVCGNNDQCNVGLICDEVCKE-----DNNAPNCFKRHL----DARRLIK 171
+C +E C +N +C D+ KE P+C +RHL +AR
Sbjct: 91 SCKADGSFDEVQCCASNGEC---YCVDKKGKELEGTRQKGRPSC-ERHLSPCEEARLQAH 146
Query: 172 SGAVDVTF--PFCEDTGMYKPVQCVGAA--CWCVEESGDEIEG 288
S ++ V P C + G Y PVQC + CWCV+E G ++ G
Sbjct: 147 SNSLRVGMFVPQCLEDGSYNPVQCWPSTGYCWCVDEGGVKVPG 189
Score = 41.6 bits (96), Expect = 0.001
Identities = 28/96 (29%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Frame = +1
Query: 196 PFCEDTGMYKPVQCVGA--ACWCVEESGDEIEGYITGIEESYGKTCN-CAKDKLEYSQRK 366
P C+ G + VQC + C+CV++ G E+EG S + + C + +L+
Sbjct: 90 PSCKADGSFDEVQCCASNGECYCVDKKGKELEGTRQKGRPSCERHLSPCEEARLQAHSNS 149
Query: 367 IVGRTF--RCDHLGNYEKVQCHGS--ICYCADLSGI 462
+ F +C G+Y VQC S C+C D G+
Sbjct: 150 LRVGMFVPQCLEDGSYNPVQCWPSTGYCWCVDEGGV 185
>sp|Q14112|NID2_HUMAN Nidogen-2 precursor (NID-2) (Osteonidogen)
Length = 1375
Score = 47.8 bits (112), Expect = 2e-05
Identities = 35/112 (31%), Positives = 48/112 (42%), Gaps = 24/112 (21%)
Frame = +1
Query: 196 PFCEDTGMYKPVQCVGAA--CWCVEESGDEIEGYITGIEESYGKTCNCAKDKLEYSQR-- 363
P C++ G + P+QC G+ CWCV+ G E+ G T G T E +QR
Sbjct: 961 PQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQT----PPGSTPPHCGPSPEPTQRPP 1016
Query: 364 -----------KIVGRTFR-------CDHLGNYEKVQCHG--SICYCADLSG 459
+ G T R CD LG++ +QCHG C+C D G
Sbjct: 1017 TICERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDG 1068
Score = 40.4 bits (93), Expect = 0.003
Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 2/37 (5%)
Frame = +1
Query: 184 DVTFPFCEDTGMYKPVQCVGAA--CWCVEESGDEIEG 288
D P C+D G + P+QC G + CWCV++ G E++G
Sbjct: 1037 DQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQG 1073
>sp|Q9BQ16|TICN3_HUMAN Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like
domains proteoglycan 3)
Length = 436
Score = 43.1 bits (100), Expect = 5e-04
Identities = 16/33 (48%), Positives = 22/33 (66%), Gaps = 2/33 (6%)
Frame = +1
Query: 196 PFCEDTGMYKPVQCVGAA--CWCVEESGDEIEG 288
P C++ G YKP QC G+ CWCV+ G+E+ G
Sbjct: 339 PLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMG 371
Score = 32.7 bits (73), Expect = 0.65
Identities = 15/36 (41%), Positives = 22/36 (61%), Gaps = 3/36 (8%)
Frame = +1
Query: 361 RKIVGRTFR-CDHLGNYEKVQCHGSI--CYCADLSG 459
+K++G+ CD G Y+ QCHGS+ C+C D G
Sbjct: 331 KKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYG 366
>sp|Q8BKV0|TICN3_MOUSE Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like
domains proteoglycan 3)
Length = 436
Score = 43.1 bits (100), Expect = 5e-04
Identities = 16/33 (48%), Positives = 22/33 (66%), Gaps = 2/33 (6%)
Frame = +1
Query: 196 PFCEDTGMYKPVQCVGAA--CWCVEESGDEIEG 288
P C++ G YKP QC G+ CWCV+ G+E+ G
Sbjct: 339 PLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVVG 371
Score = 32.7 bits (73), Expect = 0.65
Identities = 15/36 (41%), Positives = 22/36 (61%), Gaps = 3/36 (8%)
Frame = +1
Query: 361 RKIVGRTFR-CDHLGNYEKVQCHGSI--CYCADLSG 459
+K++G+ CD G Y+ QCHGS+ C+C D G
Sbjct: 331 KKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYG 366
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,312,004
Number of Sequences: 369166
Number of extensions: 1322770
Number of successful extensions: 3725
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3438
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3656
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4177115900
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)