Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01059 (862 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9QZC7|PLEB2_MOUSE Pleckstrin homology domain-containing... 69 2e-11 sp|Q96CS7|PLEB2_HUMAN Pleckstrin homology domain-containing... 69 2e-11 sp|Q9QYE9|PLEB1_MOUSE Pleckstrin homology domain-containing... 63 1e-09 sp|Q9WU68|PLEB1_RAT Pleckstrin homology domain-containing p... 63 1e-09 sp|Q9UF11|PLEB1_HUMAN Pleckstrin homology domain-containing... 61 4e-09 sp|Q9ST43|PH1_ARATH Pleckstrin homology domain-containing p... 38 0.041 sp|P47197|AKT2_RAT RAC-beta serine/threonine-protein kinase... 35 0.27 sp|P31751|AKT2_HUMAN RAC-beta serine/threonine-protein kina... 35 0.27 sp|Q60823|AKT2_MOUSE RAC-beta serine/threonine-protein kina... 35 0.27 sp|P97694|CYH1_RAT Cytohesin-1 (SEC7 homolog A) (msec7-1) 34 0.46
>sp|Q9QZC7|PLEB2_MOUSE Pleckstrin homology domain-containing protein family B member 2 (Evectin-2) Length = 221 Score = 68.9 bits (167), Expect = 2e-11 Identities = 33/102 (32%), Positives = 56/102 (54%), Gaps = 2/102 (1%) Frame = +3 Query: 36 VKAGWLYRLSDVLKVWKREWTIIYVDGSMSFLKSQDKMSPDKKINLILECKEMKSYDEF- 212 VK+GWL R S +LK WK+ W ++ DG + + Q + S + K+++ ++C +++ E Sbjct: 4 VKSGWLLRQSTILKRWKKNWFDLWSDGHLIYYDDQTRQSIEDKVHMPVDCINIRTGHECR 63 Query: 213 ESKIPDGKTRPCLFGF-SNSESSYWFCAEDEDDAMVWRLVLE 335 + + PDGK R CL + CAE DD + W+ L+ Sbjct: 64 DIQPPDGKPRDCLLQIVCRDGKTISLCAESTDDCLAWKFTLQ 105
>sp|Q96CS7|PLEB2_HUMAN Pleckstrin homology domain-containing protein family B member 2 (Evectin-2) Length = 222 Score = 68.6 bits (166), Expect = 2e-11 Identities = 30/102 (29%), Positives = 58/102 (56%), Gaps = 2/102 (1%) Frame = +3 Query: 36 VKAGWLYRLSDVLKVWKREWTIIYVDGSMSFLKSQDKMSPDKKINLILECKEMKSYDEF- 212 VK+GWL R S +LK WK+ W ++ DG + + Q + + + K+++ ++C +++ E Sbjct: 4 VKSGWLLRQSTILKRWKKNWFDLWSDGHLIYYDDQTRQNIEDKVHMPMDCINIRTGQECR 63 Query: 213 ESKIPDGKTRPCLFGF-SNSESSYWFCAEDEDDAMVWRLVLE 335 +++ PDGK++ C+ + CAE DD + W+ L+ Sbjct: 64 DTQPPDGKSKDCMLQIVCRDGKTISLCAESTDDCLAWKFTLQ 105
>sp|Q9QYE9|PLEB1_MOUSE Pleckstrin homology domain-containing protein family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain containing protein in retina 1) (PHRET1) Length = 243 Score = 62.8 bits (151), Expect = 1e-09 Identities = 29/102 (28%), Positives = 56/102 (54%), Gaps = 2/102 (1%) Frame = +3 Query: 33 IVKAGWLYRLSDVLKVWKREWTIIYVDGSMSFLKSQDKMSPDKKINLILECKEMKSYDEF 212 +V+ GWL+R S +L+ WKR W +++DG++ + + + ++ + +++K E Sbjct: 22 LVRGGWLWRQSSILRRWKRNWFALWLDGTLGYYHDETAQDEEDRVVIHFNVRDIKVGQEC 81 Query: 213 ES-KIPDGKTRPCLFGFSNSESS-YWFCAEDEDDAMVWRLVL 332 + + P+G++R L + E S CAE DDA+ W+ L Sbjct: 82 QDVQPPEGRSRDGLLTVNLREGSRLHLCAETRDDAIAWKTAL 123
>sp|Q9WU68|PLEB1_RAT Pleckstrin homology domain-containing protein family B member 1 (Evectin-1) Length = 223 Score = 62.8 bits (151), Expect = 1e-09 Identities = 29/102 (28%), Positives = 56/102 (54%), Gaps = 2/102 (1%) Frame = +3 Query: 33 IVKAGWLYRLSDVLKVWKREWTIIYVDGSMSFLKSQDKMSPDKKINLILECKEMKSYDEF 212 +V+ GWL+R S +L+ WKR W +++DG++ + + + ++ + +++K E Sbjct: 3 LVRGGWLWRQSSILRRWKRNWFALWLDGTLGYYHDETAQDEEDRVVIHFNVRDIKVGQEC 62 Query: 213 ES-KIPDGKTRPCLFGFSNSESS-YWFCAEDEDDAMVWRLVL 332 + + P+G++R L + E S CAE DDA+ W+ L Sbjct: 63 QDVQPPEGRSRDGLLTVNLREGSRLHLCAETRDDAIAWKTAL 104
>sp|Q9UF11|PLEB1_HUMAN Pleckstrin homology domain-containing protein family B member 1 (Pleckstrin homology domain retinal protein 1) (PH domain containing protein in retina 1) (PHRET1) Length = 243 Score = 61.2 bits (147), Expect = 4e-09 Identities = 28/102 (27%), Positives = 56/102 (54%), Gaps = 2/102 (1%) Frame = +3 Query: 33 IVKAGWLYRLSDVLKVWKREWTIIYVDGSMSFLKSQDKMSPDKKINLILECKEMKSYDE- 209 +V+ GWL+R S +L+ WKR W +++DG++ + + + ++ + +++K E Sbjct: 22 LVRGGWLWRQSSILRRWKRNWFALWLDGTLGYYHDETAQDEEDRVLIHFNVRDIKIGPEC 81 Query: 210 FESKIPDGKTRPCLFGFSNSESS-YWFCAEDEDDAMVWRLVL 332 + + P+G++R L + E CAE +DDA+ W+ L Sbjct: 82 HDVQPPEGRSRDGLLTVNLREGGRLHLCAETKDDALAWKTAL 123
>sp|Q9ST43|PH1_ARATH Pleckstrin homology domain-containing protein 1 (AtPH1) Length = 145 Score = 37.7 bits (86), Expect = 0.041 Identities = 23/101 (22%), Positives = 47/101 (46%), Gaps = 4/101 (3%) Frame = +3 Query: 30 NIVKAGWLYRLSDVLKVWKREWTIIYVDGSMSFLKSQD----KMSPDKKINLILECKEMK 197 N ++GWL + D +K W+R W ++ G + + K Q + S + + + +C +K Sbjct: 26 NPERSGWLTKQGDYIKTWRRRWFVL-KRGKLLWFKDQAAAGIRGSTPRGVISVGDCLTVK 84 Query: 198 SYDEFESKIPDGKTRPCLFGFSNSESSYWFCAEDEDDAMVW 320 ++ +K P F S+ + +F A++E + W Sbjct: 85 GAEDVVNK-------PFAFELSSGSYTMFFIADNEKEKEEW 118
>sp|P47197|AKT2_RAT RAC-beta serine/threonine-protein kinase (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 35.0 bits (79), Expect = 0.27 Identities = 16/61 (26%), Positives = 32/61 (52%), Gaps = 4/61 (6%) Frame = +3 Query: 30 NIVKAGWLYRLSDVLKVWKREWTIIYVDGSMSFLKSQ----DKMSPDKKINLILECKEMK 197 +++K GWL++ + +K W+ + ++ DGS K + D+ P + EC+ MK Sbjct: 5 SVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAECQLMK 64 Query: 198 S 200 + Sbjct: 65 T 65
>sp|P31751|AKT2_HUMAN RAC-beta serine/threonine-protein kinase (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 35.0 bits (79), Expect = 0.27 Identities = 16/61 (26%), Positives = 32/61 (52%), Gaps = 4/61 (6%) Frame = +3 Query: 30 NIVKAGWLYRLSDVLKVWKREWTIIYVDGSMSFLKSQ----DKMSPDKKINLILECKEMK 197 +++K GWL++ + +K W+ + ++ DGS K + D+ P + EC+ MK Sbjct: 5 SVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAECQLMK 64 Query: 198 S 200 + Sbjct: 65 T 65
>sp|Q60823|AKT2_MOUSE RAC-beta serine/threonine-protein kinase (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta) Length = 481 Score = 35.0 bits (79), Expect = 0.27 Identities = 16/61 (26%), Positives = 32/61 (52%), Gaps = 4/61 (6%) Frame = +3 Query: 30 NIVKAGWLYRLSDVLKVWKREWTIIYVDGSMSFLKSQ----DKMSPDKKINLILECKEMK 197 +++K GWL++ + +K W+ + ++ DGS K + D+ P + EC+ MK Sbjct: 5 SVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAECQLMK 64 Query: 198 S 200 + Sbjct: 65 T 65
>sp|P97694|CYH1_RAT Cytohesin-1 (SEC7 homolog A) (msec7-1) Length = 398 Score = 34.3 bits (77), Expect = 0.46 Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 5/75 (6%) Frame = +3 Query: 27 FNIVKAGWLYRLSDV-LKVWKREWTIIYVDGSMSFLKSQDKMSPDKKINL----ILECKE 191 FN + GWL +L +K WKR W I+ D + + + P I L I E ++ Sbjct: 259 FNPDREGWLLKLGGGRVKTWKRRWFIL-TDNCLYYFEYTTDKEPRGIIPLENLSIREVED 317 Query: 192 MKSYDEFESKIPDGK 236 K + FE IPD K Sbjct: 318 SKKPNCFELYIPDNK 332
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 89,201,528 Number of Sequences: 369166 Number of extensions: 1621233 Number of successful extensions: 3461 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3388 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3455 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 8534739105 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)