DrC_00979
- Cluster detail
- GO Category :
- Consensus Sequence :
BLASTX 2.2.13 [Nov-27-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00979 (1423 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P55795|HNRH2_HUMAN Heterogeneous nuclear ribonucleoprote... 148 3e-35 sp|P70333|HNRH2_MOUSE Heterogeneous nuclear ribonucleoprote... 145 2e-34 sp|O35737|HNRH1_MOUSE Heterogeneous nuclear ribonucleoprote... 145 3e-34 sp|P31943|HNRH1_HUMAN Heterogeneous nuclear ribonucleoprote... 145 3e-34 sp|Q12849|GRSF1_HUMAN G-rich sequence factor 1 (GRSF-1) 145 3e-34 sp|Q8C5Q4|GRSF1_MOUSE G-rich sequence factor 1 (GRSF-1) 140 7e-33 sp|P52597|HNRPF_HUMAN Heterogeneous nuclear ribonucleoprote... 132 3e-30 sp|Q60HC3|HNRPF_MACFA Heterogeneous nuclear ribonucleoprote... 132 3e-30 sp|Q9NTZ6|RBM12_HUMAN RNA-binding protein 12 (RNA-binding m... 80 2e-14 sp|Q8SQ27|RBM12_MACMU RNA-binding protein 12 (RNA-binding m... 80 2e-14
>sp|P55795|HNRH2_HUMAN Heterogeneous nuclear ribonucleoprotein H' (hnRNP H') (FTP-3) Length = 449 Score = 148 bits (374), Expect = 3e-35 Identities = 101/358 (28%), Positives = 164/358 (45%), Gaps = 50/358 (13%) Frame = +2 Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196 VK+RG+P+ + D+++ F I+ G GI F ++ GEAF+ELE+EE++ A Sbjct: 13 VKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLALK 72 Query: 197 RHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXINENYVLR 376 + + MG RY+EVF K + V +M V+ G N+ +V R Sbjct: 73 KDRETMGHRYVEVF---KSNSV----EMDWVLKHTGPNSPDTA----------NDGFV-R 114 Query: 377 LKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKELNGN 556 L+GLP+ SK +I +FF GL+I+P+GM++ VD G++ G+AFVQFA+ A+ A + + Sbjct: 115 LRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKE 174 Query: 557 KIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPPQSRGPRSMDDGMAYQESQR- 733 +I HRYIE+F S+ E T + M P RG S+ G ++ +R Sbjct: 175 RIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRG 234 Query: 734 ------------------------------------------------FYTRNPVIINMK 769 F + ++M+ Sbjct: 235 AYGGGYGGYDDYGGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSSFQSTTGHCVHMR 294 Query: 770 GVSISTRPDDVFRFFRPLVPLNITMRF-MSGAAEGEVDAEFANEDEAYNAMSKNRERL 940 G+ +D++ FF PL P+ + + G GE D EFA ++A AM+K++ + Sbjct: 295 GLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKDKANM 352
Score = 77.8 bits (190), Expect = 7e-14
Identities = 52/200 (26%), Positives = 94/200 (47%), Gaps = 5/200 (2%)
Frame = +2
Query: 359 ENYVLRLKGLPYNASKADIKEFFQGLKIL--PDGMSILVDHNGKALGDAFVQFATYHDAK 532
E +V++++GLP++ S ++ FF KI G+ + G+ G+AFV+ + + K
Sbjct: 9 EGFVVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVK 68
Query: 533 LAKELNGNKIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPPQSRGPRSMDDGM 712
LA + + + HRY+EVF SN E + ++ GP S D
Sbjct: 69 LALKKDRETMGHRYVEVFKSNSVEMDWVLKH-------------------TGPNSPD--- 106
Query: 713 AYQESQRFYTRNPVIINMKGVSISTRPDDVFRFFRPL--VPLNITMRF-MSGAAEGEVDA 883
T N + ++G+ +++ +FF L VP +T+ G + GE
Sbjct: 107 ---------TANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFV 157
Query: 884 EFANEDEAYNAMSKNRERLG 943
+FA+++ A A+ K++ER+G
Sbjct: 158 QFASQEIAEKALKKHKERIG 177
Score = 58.9 bits (141), Expect = 3e-08
Identities = 25/82 (30%), Positives = 50/82 (60%)
Frame = +2
Query: 14 WVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAK 193
+V+LRG+P+ + ++I++F G+ I G+ P+ + GEAF++ ++E KA
Sbjct: 112 FVRLRGLPFGCSKEEIVQFFSGLEIV--PNGMTLPVDFQGRSTGEAFVQFASQEIAEKAL 169
Query: 194 DRHNQHMGRRYIEVFSCTKGDM 259
+H + +G RYIE+F ++ ++
Sbjct: 170 KKHKERIGHRYIEIFKSSRAEV 191
Score = 52.8 bits (125), Expect = 2e-06
Identities = 27/74 (36%), Positives = 44/74 (59%)
Frame = +2
Query: 365 YVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKE 544
+ + ++GLPY A++ DI FF L P + I + +G+ G+A V+FAT+ DA A
Sbjct: 289 HCVHMRGLPYRATENDIYNFFSPLN--PMRVHIEIGPDGRVTGEADVEFATHEDAVAAMA 346
Query: 545 LNGNKIAHRYIEVF 586
+ + HRY+E+F
Sbjct: 347 KDKANMQHRYVELF 360
Score = 43.9 bits (102), Expect = 0.001
Identities = 25/74 (33%), Positives = 35/74 (47%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196
V +RG+PYR T +DI F + +H I GEA +E T ED A
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLN----PMRVHIEIGPDGRVTGEADVEFATHEDAVAAMA 346
Query: 197 RHNQHMGRRYIEVF 238
+ +M RY+E+F
Sbjct: 347 KDKANMQHRYVELF 360
Score = 35.8 bits (81), Expect = 0.31
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 5/76 (6%)
Frame = +2
Query: 743 RNPVIINMKGVSISTRPDDVFRFFRPLVPLNIT--MRFM---SGAAEGEVDAEFANEDEA 907
R ++ ++G+ S D+V RFF N T +RF+ G GE E +E+E
Sbjct: 8 REGFVVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEV 67
Query: 908 YNAMSKNRERLGSHSV 955
A+ K+RE +G V
Sbjct: 68 KLALKKDRETMGHRYV 83
>sp|P70333|HNRH2_MOUSE Heterogeneous nuclear ribonucleoprotein H' (hnRNP H') Length = 449 Score = 145 bits (367), Expect = 2e-34 Identities = 98/358 (27%), Positives = 164/358 (45%), Gaps = 50/358 (13%) Frame = +2 Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196 VK+RG+P+ + ++++ F I+ G G+ F ++ GEAF+ELE+E+++ A Sbjct: 13 VKVRGLPWSCSAEEVMRFFSDCKIQNGTSGVRFIYTREGRPSGEAFVELESEDEVKLALK 72 Query: 197 RHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXINENYVLR 376 + + MG RY+EVF K + V +M V+ G N+ +V R Sbjct: 73 KDRETMGHRYVEVF---KSNSV----EMDWVLKHTGPNSPDTA----------NDGFV-R 114 Query: 377 LKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKELNGN 556 L+GLP+ SK +I +FF GL+I+P+GM++ VD G++ G+AFVQFA+ A+ A + + Sbjct: 115 LRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKE 174 Query: 557 KIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPPQSRGPRSMDDGMAYQESQR- 733 +I HRYIE+F S+ E T + M P RG S+ G ++ +R Sbjct: 175 RIGHRYIEIFKSSRAEVRTHYDPPRKLMTMQRPGPYDRPGAGRGYNSIGRGAGFERMRRG 234 Query: 734 ------------------------------------------------FYTRNPVIINMK 769 F + ++M+ Sbjct: 235 AYGGGYGGYDDYGGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSSFQSTTGHCVHMR 294 Query: 770 GVSISTRPDDVFRFFRPLVPLNITMRF-MSGAAEGEVDAEFANEDEAYNAMSKNRERL 940 G+ +D++ FF PL P+ + + G GE D EFA ++A AM+K++ + Sbjct: 295 GLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKDKANM 352
Score = 77.8 bits (190), Expect = 7e-14
Identities = 52/200 (26%), Positives = 94/200 (47%), Gaps = 5/200 (2%)
Frame = +2
Query: 359 ENYVLRLKGLPYNASKADIKEFFQGLKIL--PDGMSILVDHNGKALGDAFVQFATYHDAK 532
E +V++++GLP++ S ++ FF KI G+ + G+ G+AFV+ + + K
Sbjct: 9 EGFVVKVRGLPWSCSAEEVMRFFSDCKIQNGTSGVRFIYTREGRPSGEAFVELESEDEVK 68
Query: 533 LAKELNGNKIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPPQSRGPRSMDDGM 712
LA + + + HRY+EVF SN E + ++ GP S D
Sbjct: 69 LALKKDRETMGHRYVEVFKSNSVEMDWVLKH-------------------TGPNSPD--- 106
Query: 713 AYQESQRFYTRNPVIINMKGVSISTRPDDVFRFFRPL--VPLNITMRF-MSGAAEGEVDA 883
T N + ++G+ +++ +FF L VP +T+ G + GE
Sbjct: 107 ---------TANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFV 157
Query: 884 EFANEDEAYNAMSKNRERLG 943
+FA+++ A A+ K++ER+G
Sbjct: 158 QFASQEIAEKALKKHKERIG 177
Score = 58.9 bits (141), Expect = 3e-08
Identities = 25/82 (30%), Positives = 50/82 (60%)
Frame = +2
Query: 14 WVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAK 193
+V+LRG+P+ + ++I++F G+ I G+ P+ + GEAF++ ++E KA
Sbjct: 112 FVRLRGLPFGCSKEEIVQFFSGLEIV--PNGMTLPVDFQGRSTGEAFVQFASQEIAEKAL 169
Query: 194 DRHNQHMGRRYIEVFSCTKGDM 259
+H + +G RYIE+F ++ ++
Sbjct: 170 KKHKERIGHRYIEIFKSSRAEV 191
Score = 52.8 bits (125), Expect = 2e-06
Identities = 27/74 (36%), Positives = 44/74 (59%)
Frame = +2
Query: 365 YVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKE 544
+ + ++GLPY A++ DI FF L P + I + +G+ G+A V+FAT+ DA A
Sbjct: 289 HCVHMRGLPYRATENDIYNFFSPLN--PMRVHIEIGPDGRVTGEADVEFATHEDAVAAMA 346
Query: 545 LNGNKIAHRYIEVF 586
+ + HRY+E+F
Sbjct: 347 KDKANMQHRYVELF 360
Score = 43.9 bits (102), Expect = 0.001
Identities = 25/74 (33%), Positives = 35/74 (47%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196
V +RG+PYR T +DI F + +H I GEA +E T ED A
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLN----PMRVHIEIGPDGRVTGEADVEFATHEDAVAAMA 346
Query: 197 RHNQHMGRRYIEVF 238
+ +M RY+E+F
Sbjct: 347 KDKANMQHRYVELF 360
>sp|O35737|HNRH1_MOUSE Heterogeneous nuclear ribonucleoprotein H (hnRNP H) Length = 449 Score = 145 bits (366), Expect = 3e-34 Identities = 98/358 (27%), Positives = 161/358 (44%), Gaps = 50/358 (13%) Frame = +2 Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196 VK+RG+P+ + D++ F I+ G +GI F ++ GEAF+ELE+E+++ A Sbjct: 13 VKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALK 72 Query: 197 RHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXINENYVLR 376 + + MG RY+EVF +M V+ G N+ +V R Sbjct: 73 KDRETMGHRYVEVFKSNN-------VEMDWVLKHTGPNSPDTA----------NDGFV-R 114 Query: 377 LKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKELNGN 556 L+GLP+ SK +I +FF GL+I+P+G+++ VD G++ G+AFVQFA+ A+ A + + Sbjct: 115 LRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKE 174 Query: 557 KIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPPQSRGPRSMDDGMAYQESQR- 733 +I HRYIE+F S+ E T + M P RG S+ G ++ +R Sbjct: 175 RIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRG 234 Query: 734 ------------------------------------------------FYTRNPVIINMK 769 F + ++M+ Sbjct: 235 AYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMR 294 Query: 770 GVSISTRPDDVFRFFRPLVPLNITMRF-MSGAAEGEVDAEFANEDEAYNAMSKNRERL 940 G+ +D++ FF PL P+ + + G GE D EFA ++A AMSK++ + Sbjct: 295 GLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANM 352
Score = 79.0 bits (193), Expect = 3e-14
Identities = 53/200 (26%), Positives = 95/200 (47%), Gaps = 5/200 (2%)
Frame = +2
Query: 359 ENYVLRLKGLPYNASKADIKEFFQGLKIL--PDGMSILVDHNGKALGDAFVQFATYHDAK 532
E +V++++GLP++ S +++ FF KI G+ + G+ G+AFV+ + + K
Sbjct: 9 EGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVK 68
Query: 533 LAKELNGNKIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPPQSRGPRSMDDGM 712
LA + + + HRY+EVF SN E + ++ GP S D
Sbjct: 69 LALKKDRETMGHRYVEVFKSNNVEMDWVLKH-------------------TGPNSPD--- 106
Query: 713 AYQESQRFYTRNPVIINMKGVSISTRPDDVFRFFRPL--VPLNITMRF-MSGAAEGEVDA 883
T N + ++G+ +++ +FF L VP IT+ G + GE
Sbjct: 107 ---------TANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFV 157
Query: 884 EFANEDEAYNAMSKNRERLG 943
+FA+++ A A+ K++ER+G
Sbjct: 158 QFASQEIAEKALKKHKERIG 177
Score = 60.1 bits (144), Expect = 2e-08
Identities = 26/82 (31%), Positives = 50/82 (60%)
Frame = +2
Query: 14 WVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAK 193
+V+LRG+P+ + ++I++F G+ I GI P+ + GEAF++ ++E KA
Sbjct: 112 FVRLRGLPFGCSKEEIVQFFSGLEIV--PNGITLPVDFQGRSTGEAFVQFASQEIAEKAL 169
Query: 194 DRHNQHMGRRYIEVFSCTKGDM 259
+H + +G RYIE+F ++ ++
Sbjct: 170 KKHKERIGHRYIEIFKSSRAEV 191
Score = 53.1 bits (126), Expect = 2e-06
Identities = 27/74 (36%), Positives = 44/74 (59%)
Frame = +2
Query: 365 YVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKE 544
+ + ++GLPY A++ DI FF L P + I + +G+ G+A V+FAT+ DA A
Sbjct: 289 HCVHMRGLPYRATENDIYNFFSPLN--PVRVHIEIGPDGRVTGEADVEFATHEDAVAAMS 346
Query: 545 LNGNKIAHRYIEVF 586
+ + HRY+E+F
Sbjct: 347 KDKANMQHRYVELF 360
Score = 43.9 bits (102), Expect = 0.001
Identities = 25/74 (33%), Positives = 35/74 (47%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196
V +RG+PYR T +DI F + +H I GEA +E T ED A
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLN----PVRVHIEIGPDGRVTGEADVEFATHEDAVAAMS 346
Query: 197 RHNQHMGRRYIEVF 238
+ +M RY+E+F
Sbjct: 347 KDKANMQHRYVELF 360
>sp|P31943|HNRH1_HUMAN Heterogeneous nuclear ribonucleoprotein H (hnRNP H) Length = 449 Score = 145 bits (366), Expect = 3e-34 Identities = 98/358 (27%), Positives = 161/358 (44%), Gaps = 50/358 (13%) Frame = +2 Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196 VK+RG+P+ + D++ F I+ G +GI F ++ GEAF+ELE+E+++ A Sbjct: 13 VKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALK 72 Query: 197 RHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXINENYVLR 376 + + MG RY+EVF +M V+ G N+ +V R Sbjct: 73 KDRETMGHRYVEVFKSNN-------VEMDWVLKHTGPNSPDTA----------NDGFV-R 114 Query: 377 LKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKELNGN 556 L+GLP+ SK +I +FF GL+I+P+G+++ VD G++ G+AFVQFA+ A+ A + + Sbjct: 115 LRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKE 174 Query: 557 KIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPPQSRGPRSMDDGMAYQESQR- 733 +I HRYIE+F S+ E T + M P RG S+ G ++ +R Sbjct: 175 RIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRG 234 Query: 734 ------------------------------------------------FYTRNPVIINMK 769 F + ++M+ Sbjct: 235 AYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMR 294 Query: 770 GVSISTRPDDVFRFFRPLVPLNITMRF-MSGAAEGEVDAEFANEDEAYNAMSKNRERL 940 G+ +D++ FF PL P+ + + G GE D EFA ++A AMSK++ + Sbjct: 295 GLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANM 352
Score = 79.0 bits (193), Expect = 3e-14
Identities = 53/200 (26%), Positives = 95/200 (47%), Gaps = 5/200 (2%)
Frame = +2
Query: 359 ENYVLRLKGLPYNASKADIKEFFQGLKIL--PDGMSILVDHNGKALGDAFVQFATYHDAK 532
E +V++++GLP++ S +++ FF KI G+ + G+ G+AFV+ + + K
Sbjct: 9 EGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVK 68
Query: 533 LAKELNGNKIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPPQSRGPRSMDDGM 712
LA + + + HRY+EVF SN E + ++ GP S D
Sbjct: 69 LALKKDRETMGHRYVEVFKSNNVEMDWVLKH-------------------TGPNSPD--- 106
Query: 713 AYQESQRFYTRNPVIINMKGVSISTRPDDVFRFFRPL--VPLNITMRF-MSGAAEGEVDA 883
T N + ++G+ +++ +FF L VP IT+ G + GE
Sbjct: 107 ---------TANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFV 157
Query: 884 EFANEDEAYNAMSKNRERLG 943
+FA+++ A A+ K++ER+G
Sbjct: 158 QFASQEIAEKALKKHKERIG 177
Score = 60.1 bits (144), Expect = 2e-08
Identities = 26/82 (31%), Positives = 50/82 (60%)
Frame = +2
Query: 14 WVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAK 193
+V+LRG+P+ + ++I++F G+ I GI P+ + GEAF++ ++E KA
Sbjct: 112 FVRLRGLPFGCSKEEIVQFFSGLEIV--PNGITLPVDFQGRSTGEAFVQFASQEIAEKAL 169
Query: 194 DRHNQHMGRRYIEVFSCTKGDM 259
+H + +G RYIE+F ++ ++
Sbjct: 170 KKHKERIGHRYIEIFKSSRAEV 191
Score = 53.1 bits (126), Expect = 2e-06
Identities = 27/74 (36%), Positives = 44/74 (59%)
Frame = +2
Query: 365 YVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKE 544
+ + ++GLPY A++ DI FF L P + I + +G+ G+A V+FAT+ DA A
Sbjct: 289 HCVHMRGLPYRATENDIYNFFSPLN--PVRVHIEIGPDGRVTGEADVEFATHEDAVAAMS 346
Query: 545 LNGNKIAHRYIEVF 586
+ + HRY+E+F
Sbjct: 347 KDKANMQHRYVELF 360
Score = 43.9 bits (102), Expect = 0.001
Identities = 25/74 (33%), Positives = 35/74 (47%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196
V +RG+PYR T +DI F + +H I GEA +E T ED A
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLN----PVRVHIEIGPDGRVTGEADVEFATHEDAVAAMS 346
Query: 197 RHNQHMGRRYIEVF 238
+ +M RY+E+F
Sbjct: 347 KDKANMQHRYVELF 360
>sp|Q12849|GRSF1_HUMAN G-rich sequence factor 1 (GRSF-1) Length = 447 Score = 145 bits (366), Expect = 3e-34 Identities = 97/341 (28%), Positives = 167/341 (48%), Gaps = 31/341 (9%) Frame = +2 Query: 11 YWVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKA 190 + ++ +G+P+ TM+D++ F I+ G+ GIHF +++ G+A IE+E+E+D+ KA Sbjct: 117 FLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKA 176 Query: 191 KDRHNQHMGRRYIEVFSCTKGDMVKACKDMPV----VVNENGXXXXXXXXXXXXXXXXIN 358 ++H +MG+RY+EV+ D+ K + V VVN+ Sbjct: 177 LEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKSSPVVNDG------------------- 217 Query: 359 ENYVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNG-KALGDAFVQFATYHDAKL 535 V+RL+GLPY+ ++ DI +FF GL I+ ++ ++D+ G + G+A+VQF A Sbjct: 218 ---VVRLRGLPYSCNEKDIVDFFAGLNIV--DITFVMDYRGRRKTGEAYVQFEEPEMANQ 272 Query: 536 AKELNGNKIAHRYIEVFDSNIEEANTEI------------------RRQMEFNDMHVKR- 658 A + +I +RYIE+F S E T + +M F + V Sbjct: 273 ALLKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEHEVNED 332 Query: 659 -----YEKSPPQSRGPRSMDDGMAYQESQRFYTRNPV-IINMKGVSISTRPDDVFRFFRP 820 +S + P+ + + + E+ F T + + ++M+G+ D+ FF P Sbjct: 333 IQPMTAFESEKEIELPKEVPEKL--PEAADFGTTSSLHFVHMRGLPFQANAQDIINFFAP 390 Query: 821 LVPLNITMRF-MSGAAEGEVDAEFANEDEAYNAMSKNRERL 940 L P+ ITM + SG A GE D F ++A AM K+R + Sbjct: 391 LKPVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHV 431
Score = 74.7 bits (182), Expect = 6e-13
Identities = 60/227 (26%), Positives = 98/227 (43%), Gaps = 37/227 (16%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNI-EWGEAFIELETEEDLNKAK 193
V+LRG+PY DI++F G+ I I F + R + GEA+++ E E N+A
Sbjct: 219 VRLRGLPYSCNEKDIVDFFAGLNIVD----ITFVMDYRGRRKTGEAYVQFEEPEMANQAL 274
Query: 194 DRHNQHMGRRYIEVFSCTKGDM-----------------VKACKDMPVVVNENGXXXXXX 322
+H + +G RYIE+F + ++ K + +V E+
Sbjct: 275 LKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEHEVNEDIQ 334
Query: 323 XXXXXXXXXXI-------------------NENYVLRLKGLPYNASKADIKEFFQGLKIL 445
I + + + ++GLP+ A+ DI FF LK
Sbjct: 335 PMTAFESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINFFAPLK-- 392
Query: 446 PDGMSILVDHNGKALGDAFVQFATYHDAKLAKELNGNKIAHRYIEVF 586
P +++ +GKA G+A V F T+ DA A + + + HRYIE+F
Sbjct: 393 PVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIELF 439
Score = 65.5 bits (158), Expect = 4e-10
Identities = 47/211 (22%), Positives = 96/211 (45%), Gaps = 4/211 (1%)
Frame = +2
Query: 353 INENYVLRLKGLPYNASKADIKEFFQGLKIL--PDGMSILVDHNGKALGDAFVQFATYHD 526
+++ +++R +GLP++ + D+ FF +I +G+ L++ +GK GDA ++ + D
Sbjct: 113 VDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQD 172
Query: 527 AKLAKELNGNKIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPPQSRGPRSMDD 706
+ A E + + RY+EV++ N E+ + ++ + VK SP + G
Sbjct: 173 VQKALEKHRMYMGQRYVEVYEINNEDVDALMK------SLQVK---SSPVVNDG------ 217
Query: 707 GMAYQESQRFYTRNPVIINMKGVSISTRPDDVFRFFRPL--VPLNITMRFMSGAAEGEVD 880
++ ++G+ S D+ FF L V + M + GE
Sbjct: 218 ----------------VVRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAY 261
Query: 881 AEFANEDEAYNAMSKNRERLGSHSVFLSVIP 973
+F + A A+ K+RE +G+ ++ + P
Sbjct: 262 VQFEEPEMANQALLKHREEIGNR--YIEIFP 290
Score = 43.9 bits (102), Expect = 0.001
Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
Frame = +2
Query: 5 SEYWVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLN 184
S ++V +RG+P++ DII F + I S GEA + ET ED
Sbjct: 366 SLHFVHMRGLPFQANAQDIINFFAPLK----PVRITMEYSSSGKATGEADVHFETHEDAV 421
Query: 185 KAKDRHNQHMGRRYIEVF--SCTKG 253
A + H+ RYIE+F SC KG
Sbjct: 422 AAMLKDRSHVHHRYIELFLNSCPKG 446
>sp|Q8C5Q4|GRSF1_MOUSE G-rich sequence factor 1 (GRSF-1) Length = 479 Score = 140 bits (354), Expect = 7e-33 Identities = 94/337 (27%), Positives = 163/337 (48%), Gaps = 27/337 (8%) Frame = +2 Query: 11 YWVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKA 190 Y ++ +G+P+ T++D++ F I+ + GIHF +++ G+A IE+E+E+D+ KA Sbjct: 149 YLIRAQGLPWSCTVEDVLNFFSDCRIRNSENGIHFLLNRDGKRRGDALIEMESEQDVQKA 208 Query: 191 KDRHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXINENYV 370 ++H +MG+RY+EV+ D+ K + V + + V Sbjct: 209 LEKHRMYMGQRYVEVYEINNEDVDALMKSLQV------------------KPSPVLSDGV 250 Query: 371 LRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNG-KALGDAFVQFATYHDAKLAKEL 547 +RL+GLPY+ ++ DI +FF GL I+ ++ ++D+ G + G+A+VQF A A Sbjct: 251 VRLRGLPYSCNEKDIVDFFAGLNIV--DITFVMDYRGRRKTGEAYVQFEEPEMANQALLK 308 Query: 548 NGNKIAHRYIEVFDSNIEEANTEIR-----------------------RQMEFN-DMHVK 655 + +I +RYIE+F S E T + + E N D+ Sbjct: 309 HREEIGNRYIEIFPSRRNEVRTHVGSHKGKKMTSSPPTKYITEPEVVFEEHEVNEDIRPM 368 Query: 656 RYEKSPPQSRGPRSMDDGMAYQESQRFYTRNPV-IINMKGVSISTRPDDVFRFFRPLVPL 832 +S + P+ M + + E+ F T + ++M+G+ D+ FF PL P+ Sbjct: 369 TAFESDKEIELPKEMSEKL--PEAVDFGTLPSLHFVHMRGLPFQANAQDIINFFAPLKPV 426 Query: 833 NITMRF-MSGAAEGEVDAEFANEDEAYNAMSKNRERL 940 ITM + SG A GE D F ++A AM K+R + Sbjct: 427 RITMEYSSSGKATGEADVHFDTHEDAVAAMLKDRSHV 463
Score = 76.3 bits (186), Expect = 2e-13
Identities = 62/232 (26%), Positives = 100/232 (43%), Gaps = 37/232 (15%)
Frame = +2
Query: 2 MSEYWVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQR-NIEWGEAFIELETEED 178
+S+ V+LRG+PY DI++F G+ I I F + R + GEA+++ E E
Sbjct: 246 LSDGVVRLRGLPYSCNEKDIVDFFAGLNIV----DITFVMDYRGRRKTGEAYVQFEEPEM 301
Query: 179 LNKAKDRHNQHMGRRYIEVFSCTKGDM-----------------VKACKDMPVVVNENGX 307
N+A +H + +G RYIE+F + ++ K + VV E+
Sbjct: 302 ANQALLKHREEIGNRYIEIFPSRRNEVRTHVGSHKGKKMTSSPPTKYITEPEVVFEEHEV 361
Query: 308 XXXXXXXXXXXXXXXIN-------------------ENYVLRLKGLPYNASKADIKEFFQ 430
I + + ++GLP+ A+ DI FF
Sbjct: 362 NEDIRPMTAFESDKEIELPKEMSEKLPEAVDFGTLPSLHFVHMRGLPFQANAQDIINFFA 421
Query: 431 GLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKELNGNKIAHRYIEVF 586
LK P +++ +GKA G+A V F T+ DA A + + + HRYIE+F
Sbjct: 422 PLK--PVRITMEYSSSGKATGEADVHFDTHEDAVAAMLKDRSHVQHRYIELF 471
Score = 67.4 bits (163), Expect = 1e-10
Identities = 49/211 (23%), Positives = 96/211 (45%), Gaps = 4/211 (1%)
Frame = +2
Query: 353 INENYVLRLKGLPYNASKADIKEFFQGLKI--LPDGMSILVDHNGKALGDAFVQFATYHD 526
+++ Y++R +GLP++ + D+ FF +I +G+ L++ +GK GDA ++ + D
Sbjct: 145 VDDVYLIRAQGLPWSCTVEDVLNFFSDCRIRNSENGIHFLLNRDGKRRGDALIEMESEQD 204
Query: 527 AKLAKELNGNKIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPPQSRGPRSMDD 706
+ A E + + RY+EV++ N E+ + ++ + VK SP S G
Sbjct: 205 VQKALEKHRMYMGQRYVEVYEINNEDVDALMK------SLQVK---PSPVLSDG------ 249
Query: 707 GMAYQESQRFYTRNPVIINMKGVSISTRPDDVFRFFRPL--VPLNITMRFMSGAAEGEVD 880
++ ++G+ S D+ FF L V + M + GE
Sbjct: 250 ----------------VVRLRGLPYSCNEKDIVDFFAGLNIVDITFVMDYRGRRKTGEAY 293
Query: 881 AEFANEDEAYNAMSKNRERLGSHSVFLSVIP 973
+F + A A+ K+RE +G+ ++ + P
Sbjct: 294 VQFEEPEMANQALLKHREEIGNR--YIEIFP 322
Score = 42.7 bits (99), Expect = 0.003
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
Frame = +2
Query: 5 SEYWVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLN 184
S ++V +RG+P++ DII F + I S GEA + +T ED
Sbjct: 398 SLHFVHMRGLPFQANAQDIINFFAPLK----PVRITMEYSSSGKATGEADVHFDTHEDAV 453
Query: 185 KAKDRHNQHMGRRYIEVF--SCTKG 253
A + H+ RYIE+F SC KG
Sbjct: 454 AAMLKDRSHVQHRYIELFLNSCPKG 478
>sp|P52597|HNRPF_HUMAN Heterogeneous nuclear ribonucleoprotein F (hnRNP F) (Nucleolin-like protein mcs94-1) Length = 415 Score = 132 bits (331), Expect = 3e-30 Identities = 79/214 (36%), Positives = 122/214 (57%) Frame = +2 Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196 VKLRG+P+ +++D+ FL TI G G+HF ++ + GEAF+EL +E+D+ A Sbjct: 13 VKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALK 72 Query: 197 RHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXINENYVLR 376 + + MG RYIEVF + +M V+ +G N+ +V R Sbjct: 73 KDRESMGHRYIEVFKSHR-------TEMDWVLKHSGPNSADSA----------NDGFV-R 114 Query: 377 LKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKELNGN 556 L+GLP+ +K +I +FF GL+I+P+G+++ VD GK G+AFVQFA+ A+ A + Sbjct: 115 LRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKE 174 Query: 557 KIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKR 658 +I HRYIEVF S+ EE + ++F M V+R Sbjct: 175 RIGHRYIEVFKSSQEEVRSYSDPPLKF--MSVQR 206
Score = 74.7 bits (182), Expect = 6e-13
Identities = 54/200 (27%), Positives = 94/200 (47%), Gaps = 5/200 (2%)
Frame = +2
Query: 359 ENYVLRLKGLPYNASKADIKEFFQGLKILPD--GMSILVDHNGKALGDAFVQFATYHDAK 532
E +V++L+GLP++ S D++ F I G+ + G+ G+AFV+ + D K
Sbjct: 9 EGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVK 68
Query: 533 LAKELNGNKIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPPQSRGPRSMDDGM 712
+A + + + HRYIEVF S+ R +M++ H GP S D
Sbjct: 69 MALKKDRESMGHRYIEVFKSH--------RTEMDWVLKH-----------SGPNSAD--- 106
Query: 713 AYQESQRFYTRNPVIINMKGVSISTRPDDVFRFFRPL--VPLNITMRF-MSGAAEGEVDA 883
+ N + ++G+ +++ +FF L VP IT+ G GE
Sbjct: 107 ---------SANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFV 157
Query: 884 EFANEDEAYNAMSKNRERLG 943
+FA+++ A A+ K++ER+G
Sbjct: 158 QFASQELAEKALGKHKERIG 177
Score = 61.2 bits (147), Expect = 7e-09
Identities = 31/91 (34%), Positives = 54/91 (59%)
Frame = +2
Query: 14 WVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAK 193
+V+LRG+P+ T ++I++F G+ I GI P+ GEAF++ ++E KA
Sbjct: 112 FVRLRGLPFGCTKEEIVQFFSGLEIV--PNGITLPVDPEGKITGEAFVQFASQELAEKAL 169
Query: 194 DRHNQHMGRRYIEVFSCTKGDMVKACKDMPV 286
+H + +G RYIEVF ++ + V++ D P+
Sbjct: 170 GKHKERIGHRYIEVFKSSQ-EEVRSYSDPPL 199
Score = 52.0 bits (123), Expect = 4e-06
Identities = 27/74 (36%), Positives = 44/74 (59%)
Frame = +2
Query: 365 YVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKE 544
+ + ++GLPY A++ DI FF L P + I + +G+ G+A V+FAT+ +A A
Sbjct: 289 HCVHMRGLPYKATENDIYNFFSPLN--PVRVHIEIGPDGRVTGEADVEFATHEEAVAAMS 346
Query: 545 LNGNKIAHRYIEVF 586
+ + HRYIE+F
Sbjct: 347 KDRANMQHRYIELF 360
Score = 47.4 bits (111), Expect = 1e-04
Identities = 22/62 (35%), Positives = 35/62 (56%), Gaps = 1/62 (1%)
Frame = +2
Query: 758 INMKGVSISTRPDDVFRFFRPLVPLNITMRF-MSGAAEGEVDAEFANEDEAYNAMSKNRE 934
++M+G+ +D++ FF PL P+ + + G GE D EFA +EA AMSK+R
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRA 350
Query: 935 RL 940
+
Sbjct: 351 NM 352
Score = 41.6 bits (96), Expect = 0.006
Identities = 24/74 (32%), Positives = 35/74 (47%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196
V +RG+PY+ T +DI F + +H I GEA +E T E+ A
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLN----PVRVHIEIGPDGRVTGEADVEFATHEEAVAAMS 346
Query: 197 RHNQHMGRRYIEVF 238
+ +M RYIE+F
Sbjct: 347 KDRANMQHRYIELF 360
>sp|Q60HC3|HNRPF_MACFA Heterogeneous nuclear ribonucleoprotein F (hnRNP F) Length = 415 Score = 132 bits (331), Expect = 3e-30 Identities = 79/214 (36%), Positives = 122/214 (57%) Frame = +2 Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196 VKLRG+P+ +++D+ FL TI G G+HF ++ + GEAF+EL +E+D+ A Sbjct: 13 VKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALK 72 Query: 197 RHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXINENYVLR 376 + + MG RYIEVF + +M V+ +G N+ +V R Sbjct: 73 KDRESMGHRYIEVFKSHR-------TEMDWVLKHSGPNSADSA----------NDGFV-R 114 Query: 377 LKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKELNGN 556 L+GLP+ +K +I +FF GL+I+P+G+++ VD GK G+AFVQFA+ A+ A + Sbjct: 115 LRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKE 174 Query: 557 KIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKR 658 +I HRYIEVF S+ EE + ++F M V+R Sbjct: 175 RIGHRYIEVFKSSQEEVRSYSDPPLKF--MSVQR 206
Score = 74.7 bits (182), Expect = 6e-13
Identities = 54/200 (27%), Positives = 94/200 (47%), Gaps = 5/200 (2%)
Frame = +2
Query: 359 ENYVLRLKGLPYNASKADIKEFFQGLKILPD--GMSILVDHNGKALGDAFVQFATYHDAK 532
E +V++L+GLP++ S D++ F I G+ + G+ G+AFV+ + D K
Sbjct: 9 EGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVK 68
Query: 533 LAKELNGNKIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPPQSRGPRSMDDGM 712
+A + + + HRYIEVF S+ R +M++ H GP S D
Sbjct: 69 MALKKDRESMGHRYIEVFKSH--------RTEMDWVLKH-----------SGPNSAD--- 106
Query: 713 AYQESQRFYTRNPVIINMKGVSISTRPDDVFRFFRPL--VPLNITMRF-MSGAAEGEVDA 883
+ N + ++G+ +++ +FF L VP IT+ G GE
Sbjct: 107 ---------SANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFV 157
Query: 884 EFANEDEAYNAMSKNRERLG 943
+FA+++ A A+ K++ER+G
Sbjct: 158 QFASQELAEKALGKHKERIG 177
Score = 61.2 bits (147), Expect = 7e-09
Identities = 31/91 (34%), Positives = 54/91 (59%)
Frame = +2
Query: 14 WVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAK 193
+V+LRG+P+ T ++I++F G+ I GI P+ GEAF++ ++E KA
Sbjct: 112 FVRLRGLPFGCTKEEIVQFFSGLEIV--PNGITLPVDPEGKITGEAFVQFASQELAEKAL 169
Query: 194 DRHNQHMGRRYIEVFSCTKGDMVKACKDMPV 286
+H + +G RYIEVF ++ + V++ D P+
Sbjct: 170 GKHKERIGHRYIEVFKSSQ-EEVRSYSDPPL 199
Score = 52.0 bits (123), Expect = 4e-06
Identities = 27/74 (36%), Positives = 44/74 (59%)
Frame = +2
Query: 365 YVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKE 544
+ + ++GLPY A++ DI FF L P + I + +G+ G+A V+FAT+ +A A
Sbjct: 289 HCVHMRGLPYKATENDIYNFFSPLN--PVRVHIEIGPDGRVTGEADVEFATHEEAVAAMS 346
Query: 545 LNGNKIAHRYIEVF 586
+ + HRYIE+F
Sbjct: 347 KDRANMQHRYIELF 360
Score = 47.4 bits (111), Expect = 1e-04
Identities = 22/62 (35%), Positives = 35/62 (56%), Gaps = 1/62 (1%)
Frame = +2
Query: 758 INMKGVSISTRPDDVFRFFRPLVPLNITMRF-MSGAAEGEVDAEFANEDEAYNAMSKNRE 934
++M+G+ +D++ FF PL P+ + + G GE D EFA +EA AMSK+R
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVAAMSKDRA 350
Query: 935 RL 940
+
Sbjct: 351 NM 352
Score = 41.6 bits (96), Expect = 0.006
Identities = 24/74 (32%), Positives = 35/74 (47%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196
V +RG+PY+ T +DI F + +H I GEA +E T E+ A
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLN----PVRVHIEIGPDGRVTGEADVEFATHEEAVAAMS 346
Query: 197 RHNQHMGRRYIEVF 238
+ +M RYIE+F
Sbjct: 347 KDRANMQHRYIELF 360
>sp|Q9NTZ6|RBM12_HUMAN RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN) Length = 932 Score = 79.7 bits (195), Expect = 2e-14 Identities = 55/223 (24%), Positives = 99/223 (44%), Gaps = 1/223 (0%) Frame = +2 Query: 11 YWVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKA 190 + V L+G+P+ +I+F + I + I+ GE F+E E D A Sbjct: 430 FCVYLKGLPFEAENKHVIDFFKKLDIV--EDSIYIAYGPNGKATGEGFVEFRNEADYKAA 487 Query: 191 KDRHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXINENYV 370 RH Q+MG R+I+V TK M++ + ++ +N V Sbjct: 488 LCRHKQYMGNRFIQVHPITKKGMLEK---IDMIRKRLQNFSYDQREMILNPEGDVNSAKV 544 Query: 371 L-RLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKEL 547 + +P++ +K D+ +F +G+ + + + +LVD+NG+ LG A VQF DA+ ++ L Sbjct: 545 CAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERL 604 Query: 548 NGNKIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPP 676 + K+ R V +E+ ++ EK+PP Sbjct: 605 HRKKLNGREAFVHVVTLED---------------MREIEKNPP 632
Score = 66.6 bits (161), Expect = 2e-10
Identities = 70/338 (20%), Positives = 128/338 (37%), Gaps = 15/338 (4%)
Frame = +2
Query: 8 EYWVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNK 187
+ +V + GMP+ +D+ +F G+ + +H G ++ + +D +
Sbjct: 303 DLYVSVHGMPFSAMENDVRDFFHGLRVDA----VHLLKDHVGRNNGNGLVKFLSPQDTFE 358
Query: 188 AKDRHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXIN--- 358
A R+ M +RY+EV T+ V A + N +
Sbjct: 359 ALKRNRMLMIQRYVEVSPATERQWVAAGGHITFKQNMGPSGQTHPPPQTLPRSKSPSGQK 418
Query: 359 ---------ENYVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQF 511
+ + LKGLP+ A + +FF+ L I+ D + I NGKA G+ FV+F
Sbjct: 419 RSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEF 478
Query: 512 ATYHDAKLAKELNGNKIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPPQSRGP 691
D K A + + +R+I+V + +E DM KR +
Sbjct: 479 RNEADYKAALCRHKQYMGNRFIQVHP-------ITKKGMLEKIDMIRKRLQNF------- 524
Query: 692 RSMDDGMAYQESQRFYTRNPVIINMKGVSISTRPDDVFRFFRPLVPLNITMRFM---SGA 862
S D + V ++ + S DV +F + + + +G
Sbjct: 525 -SYDQREMILNPEGDVNSAKVCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQ 583
Query: 863 AEGEVDAEFANEDEAYNAMSKNRERLGSHSVFLSVIPI 976
G+ +F NED+A + +R++L F+ V+ +
Sbjct: 584 GLGQALVQFKNEDDARKSERLHRKKLNGREAFVHVVTL 621
Score = 65.9 bits (159), Expect = 3e-10
Identities = 53/211 (25%), Positives = 97/211 (45%), Gaps = 3/211 (1%)
Frame = +2
Query: 359 ENYVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLA 538
++ + + G+P++A + D+++FF GL++ D + +L DH G+ G+ V+F + D A
Sbjct: 302 DDLYVSVHGMPFSAMENDVRDFFHGLRV--DAVHLLKDHVGRNNGNGLVKFLSPQDTFEA 359
Query: 539 KELNGNKIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPPQSRGPRSMDDGMAY 718
+ N + RY+EV + E + F + PP PRS
Sbjct: 360 LKRNRMLMIQRYVEVSPAT-ERQWVAAGGHITFKQNMGPSGQTHPPPQTLPRSKSPSGQK 418
Query: 719 QESQRFYTRNPVIINMKGVSISTRPDDVFRFFRPL--VPLNITMRF-MSGAAEGEVDAEF 889
+ R + +KG+ V FF+ L V +I + + +G A GE EF
Sbjct: 419 RSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEF 478
Query: 890 ANEDEAYNAMSKNRERLGSHSVFLSVIPIVR 982
NE + A+ ++++ +G+ F+ V PI +
Sbjct: 479 RNEADYKAALCRHKQYMGNR--FIQVHPITK 507
Score = 53.5 bits (127), Expect = 1e-06
Identities = 41/116 (35%), Positives = 56/116 (48%), Gaps = 6/116 (5%)
Frame = +2
Query: 368 VLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKEL 547
V+RL+GLP A DI+ FF GL I G+ I+ G LG+AF+ FAT DA+L
Sbjct: 4 VIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIV----GGELGEAFIVFATDEDARLGMMR 59
Query: 548 NGNKIAHRYIEVFDSNIEEANTEI---RRQMEFNDMHVKRYEKS---PPQSRGPRS 697
G I + + S+ E I RR+ E ++ + S PP S G S
Sbjct: 60 TGGTIKGSKVTLLLSSKTEMQNMIELSRRRFETANLDIPPANASRSGPPPSSGMSS 115
Score = 39.7 bits (91), Expect = 0.022
Identities = 19/73 (26%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
Frame = +2
Query: 368 VLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAK-E 544
V++++ +P+ S +I +FF G +++P + + + G G+A V F + +A A +
Sbjct: 857 VIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVID 916
Query: 545 LNGNKIAHRYIEV 583
LN I R +++
Sbjct: 917 LNDRPIGSRKVKL 929
Score = 33.5 bits (75), Expect = 1.6
Identities = 16/74 (21%), Positives = 42/74 (56%), Gaps = 1/74 (1%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAK- 193
+K++ MP+ ++D+I++F G + G + +++ + GEA + E+ ++ A
Sbjct: 858 IKVQNMPFTVSIDEILDFFYGYQVIPG--SVCLKYNEKGMPTGEAMVAFESRDEATAAVI 915
Query: 194 DRHNQHMGRRYIEV 235
D +++ +G R +++
Sbjct: 916 DLNDRPIGSRKVKL 929
Score = 33.1 bits (74), Expect = 2.0
Identities = 21/54 (38%), Positives = 28/54 (51%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEED 178
++L+G+P DI F G+TI G G+H E GEAFI T+ED
Sbjct: 5 IRLQGLPIVAGTMDIRHFFSGLTIPDG--GVHIV----GGELGEAFIVFATDED 52
>sp|Q8SQ27|RBM12_MACMU RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN) Length = 932 Score = 79.7 bits (195), Expect = 2e-14 Identities = 55/223 (24%), Positives = 99/223 (44%), Gaps = 1/223 (0%) Frame = +2 Query: 11 YWVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKA 190 + V L+G+P+ +I+F + I + I+ GE F+E E D A Sbjct: 430 FCVYLKGLPFEAENKHVIDFFKKLDIV--EDSIYIAYGPNGKATGEGFVEFRNEADYKAA 487 Query: 191 KDRHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXINENYV 370 RH Q+MG R+I+V TK M++ + ++ +N V Sbjct: 488 LCRHKQYMGNRFIQVHPITKKGMLEK---IDMIRKRLQNFSYDQREMMLNPEGDVNSAKV 544 Query: 371 L-RLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKEL 547 + +P++ +K D+ +F +G+ + + + +LVD+NG+ LG A VQF DA+ ++ L Sbjct: 545 CAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERL 604 Query: 548 NGNKIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPP 676 + K+ R V +E+ ++ EK+PP Sbjct: 605 HRKKLNGREAFVHVVTLED---------------MREIEKNPP 632
Score = 67.0 bits (162), Expect = 1e-10
Identities = 70/338 (20%), Positives = 128/338 (37%), Gaps = 15/338 (4%)
Frame = +2
Query: 8 EYWVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNK 187
+ +V + GMP+ +D+ +F G+ + +H G ++ + +D +
Sbjct: 303 DLYVSVHGMPFSAMENDVRDFFHGLRVDA----VHLLKDHVGRNNGNGLVKFLSPQDTFE 358
Query: 188 AKDRHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXIN--- 358
A R+ M +RY+EV T+ V A + N +
Sbjct: 359 ALKRNRMLMIQRYVEVSPATERQWVAAGGHITFKQNMGPSGQSHPPPQTLPRSKSPSGQK 418
Query: 359 ---------ENYVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQF 511
+ + LKGLP+ A + +FF+ L I+ D + I NGKA G+ FV+F
Sbjct: 419 RSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEF 478
Query: 512 ATYHDAKLAKELNGNKIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPPQSRGP 691
D K A + + +R+I+V + +E DM KR + R
Sbjct: 479 RNEADYKAALCRHKQYMGNRFIQVHP-------ITKKGMLEKIDMIRKRLQNFSYDQREM 531
Query: 692 RSMDDGMAYQESQRFYTRNPVIINMKGVSISTRPDDVFRFFRPLVPLNITMRFM---SGA 862
+G V ++ + S DV +F + + + +G
Sbjct: 532 MLNPEGDVNSAK--------VCAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQ 583
Query: 863 AEGEVDAEFANEDEAYNAMSKNRERLGSHSVFLSVIPI 976
G+ +F NED+A + +R++L F+ V+ +
Sbjct: 584 GLGQALVQFKNEDDARKSERLHRKKLNGREAFVHVVTL 621
Score = 66.2 bits (160), Expect = 2e-10
Identities = 53/211 (25%), Positives = 97/211 (45%), Gaps = 3/211 (1%)
Frame = +2
Query: 359 ENYVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLA 538
++ + + G+P++A + D+++FF GL++ D + +L DH G+ G+ V+F + D A
Sbjct: 302 DDLYVSVHGMPFSAMENDVRDFFHGLRV--DAVHLLKDHVGRNNGNGLVKFLSPQDTFEA 359
Query: 539 KELNGNKIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPPQSRGPRSMDDGMAY 718
+ N + RY+EV + E + F + PP PRS
Sbjct: 360 LKRNRMLMIQRYVEVSPAT-ERQWVAAGGHITFKQNMGPSGQSHPPPQTLPRSKSPSGQK 418
Query: 719 QESQRFYTRNPVIINMKGVSISTRPDDVFRFFRPL--VPLNITMRF-MSGAAEGEVDAEF 889
+ R + +KG+ V FF+ L V +I + + +G A GE EF
Sbjct: 419 RSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEF 478
Query: 890 ANEDEAYNAMSKNRERLGSHSVFLSVIPIVR 982
NE + A+ ++++ +G+ F+ V PI +
Sbjct: 479 RNEADYKAALCRHKQYMGNR--FIQVHPITK 507
Score = 53.1 bits (126), Expect = 2e-06
Identities = 40/113 (35%), Positives = 55/113 (48%), Gaps = 6/113 (5%)
Frame = +2
Query: 368 VLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKEL 547
V+RL+GLP A DI+ FF GL I G+ I+ G LG+AF+ FAT DA+L
Sbjct: 4 VIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIV----GGELGEAFIVFATDEDARLGMMR 59
Query: 548 NGNKIAHRYIEVFDSNIEEANTEI---RRQMEFNDMHVKRYEKS---PPQSRG 688
G I + + S+ E I RR+ E ++ + S PP S G
Sbjct: 60 TGGTIKGSKVTLLLSSKTEMQNMIELSRRRFETANLDIPPANASRSGPPPSSG 112
Score = 39.7 bits (91), Expect = 0.022
Identities = 19/73 (26%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
Frame = +2
Query: 368 VLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAK-E 544
V++++ +P+ S +I +FF G +++P + + + G G+A V F + +A A +
Sbjct: 857 VIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVID 916
Query: 545 LNGNKIAHRYIEV 583
LN I R +++
Sbjct: 917 LNDRPIGSRKVKL 929
Score = 33.5 bits (75), Expect = 1.6
Identities = 16/74 (21%), Positives = 42/74 (56%), Gaps = 1/74 (1%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAK- 193
+K++ MP+ ++D+I++F G + G + +++ + GEA + E+ ++ A
Sbjct: 858 IKVQNMPFTVSIDEILDFFYGYQVIPG--SVCLKYNEKGMPTGEAMVAFESRDEATAAVI 915
Query: 194 DRHNQHMGRRYIEV 235
D +++ +G R +++
Sbjct: 916 DLNDRPIGSRKVKL 929
Score = 33.1 bits (74), Expect = 2.0
Identities = 21/54 (38%), Positives = 28/54 (51%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEED 178
++L+G+P DI F G+TI G G+H E GEAFI T+ED
Sbjct: 5 IRLQGLPIVAGTMDIRHFFSGLTIPDG--GVHIV----GGELGEAFIVFATDED 52
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 144,377,507
Number of Sequences: 369166
Number of extensions: 2757233
Number of successful extensions: 7538
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6907
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7451
length of database: 68,354,980
effective HSP length: 114
effective length of database: 47,295,190
effective search space used: 16978973210
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Cluster detail
