Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_L15
(805 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P55795|HNRH2_HUMAN Heterogeneous nuclear ribonucleoprote... 132 8e-31
sp|P52597|HNRPF_HUMAN Heterogeneous nuclear ribonucleoprote... 132 1e-30
sp|Q60HC3|HNRPF_MACFA Heterogeneous nuclear ribonucleoprote... 132 1e-30
sp|P70333|HNRH2_MOUSE Heterogeneous nuclear ribonucleoprote... 130 5e-30
sp|O35737|HNRH1_MOUSE Heterogeneous nuclear ribonucleoprote... 129 1e-29
sp|P31943|HNRH1_HUMAN Heterogeneous nuclear ribonucleoprote... 129 1e-29
sp|Q12849|GRSF1_HUMAN G-rich sequence factor 1 (GRSF-1) 117 3e-26
sp|Q8C5Q4|GRSF1_MOUSE G-rich sequence factor 1 (GRSF-1) 114 3e-25
sp|Q9NTZ6|RBM12_HUMAN RNA-binding protein 12 (RNA-binding m... 80 8e-15
sp|Q8SQ27|RBM12_MACMU RNA-binding protein 12 (RNA-binding m... 80 8e-15
>sp|P55795|HNRH2_HUMAN Heterogeneous nuclear ribonucleoprotein H' (hnRNP H') (FTP-3)
Length = 449
Score = 132 bits (333), Expect = 8e-31
Identities = 81/239 (33%), Positives = 127/239 (53%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196
VK+RG+P+ + D+++ F I+ G GI F ++ GEAF+ELE+EE++ A
Sbjct: 13 VKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLALK 72
Query: 197 RHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXINENYVLR 376
+ + MG RY+EVF K + V +M V+ G N+ +V R
Sbjct: 73 KDRETMGHRYVEVF---KSNSV----EMDWVLKHTGPNSPDTA----------NDGFV-R 114
Query: 377 LKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKELNGN 556
L+GLP+ SK +I +FF GL+I+P+GM++ VD G++ G+AFVQFA+ A+ A + +
Sbjct: 115 LRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKE 174
Query: 557 KIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPPQSRGPRSMDDGMAYQESQR 733
+I HRYIE+F S+ E T + M P RG S+ G ++ +R
Sbjct: 175 RIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRR 233
Score = 58.9 bits (141), Expect = 2e-08
Identities = 25/82 (30%), Positives = 50/82 (60%)
Frame = +2
Query: 14 WVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAK 193
+V+LRG+P+ + ++I++F G+ I G+ P+ + GEAF++ ++E KA
Sbjct: 112 FVRLRGLPFGCSKEEIVQFFSGLEIV--PNGMTLPVDFQGRSTGEAFVQFASQEIAEKAL 169
Query: 194 DRHNQHMGRRYIEVFSCTKGDM 259
+H + +G RYIE+F ++ ++
Sbjct: 170 KKHKERIGHRYIEIFKSSRAEV 191
Score = 57.8 bits (138), Expect = 3e-08
Identities = 28/84 (33%), Positives = 48/84 (57%), Gaps = 2/84 (2%)
Frame = +2
Query: 359 ENYVLRLKGLPYNASKADIKEFFQGLKIL--PDGMSILVDHNGKALGDAFVQFATYHDAK 532
E +V++++GLP++ S ++ FF KI G+ + G+ G+AFV+ + + K
Sbjct: 9 EGFVVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVK 68
Query: 533 LAKELNGNKIAHRYIEVFDSNIEE 604
LA + + + HRY+EVF SN E
Sbjct: 69 LALKKDRETMGHRYVEVFKSNSVE 92
Score = 52.8 bits (125), Expect = 1e-06
Identities = 27/74 (36%), Positives = 44/74 (59%)
Frame = +2
Query: 365 YVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKE 544
+ + ++GLPY A++ DI FF L P + I + +G+ G+A V+FAT+ DA A
Sbjct: 289 HCVHMRGLPYRATENDIYNFFSPLN--PMRVHIEIGPDGRVTGEADVEFATHEDAVAAMA 346
Query: 545 LNGNKIAHRYIEVF 586
+ + HRY+E+F
Sbjct: 347 KDKANMQHRYVELF 360
Score = 43.9 bits (102), Expect = 5e-04
Identities = 25/74 (33%), Positives = 35/74 (47%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196
V +RG+PYR T +DI F + +H I GEA +E T ED A
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLN----PMRVHIEIGPDGRVTGEADVEFATHEDAVAAMA 346
Query: 197 RHNQHMGRRYIEVF 238
+ +M RY+E+F
Sbjct: 347 KDKANMQHRYVELF 360
>sp|P52597|HNRPF_HUMAN Heterogeneous nuclear ribonucleoprotein F (hnRNP F) (Nucleolin-like
protein mcs94-1)
Length = 415
Score = 132 bits (331), Expect = 1e-30
Identities = 79/214 (36%), Positives = 122/214 (57%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196
VKLRG+P+ +++D+ FL TI G G+HF ++ + GEAF+EL +E+D+ A
Sbjct: 13 VKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALK 72
Query: 197 RHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXINENYVLR 376
+ + MG RYIEVF + +M V+ +G N+ +V R
Sbjct: 73 KDRESMGHRYIEVFKSHR-------TEMDWVLKHSGPNSADSA----------NDGFV-R 114
Query: 377 LKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKELNGN 556
L+GLP+ +K +I +FF GL+I+P+G+++ VD GK G+AFVQFA+ A+ A +
Sbjct: 115 LRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKE 174
Query: 557 KIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKR 658
+I HRYIEVF S+ EE + ++F M V+R
Sbjct: 175 RIGHRYIEVFKSSQEEVRSYSDPPLKF--MSVQR 206
Score = 61.2 bits (147), Expect = 3e-09
Identities = 31/91 (34%), Positives = 54/91 (59%)
Frame = +2
Query: 14 WVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAK 193
+V+LRG+P+ T ++I++F G+ I GI P+ GEAF++ ++E KA
Sbjct: 112 FVRLRGLPFGCTKEEIVQFFSGLEIV--PNGITLPVDPEGKITGEAFVQFASQELAEKAL 169
Query: 194 DRHNQHMGRRYIEVFSCTKGDMVKACKDMPV 286
+H + +G RYIEVF ++ + V++ D P+
Sbjct: 170 GKHKERIGHRYIEVFKSSQ-EEVRSYSDPPL 199
Score = 55.5 bits (132), Expect = 2e-07
Identities = 28/84 (33%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
Frame = +2
Query: 359 ENYVLRLKGLPYNASKADIKEFFQGLKILPD--GMSILVDHNGKALGDAFVQFATYHDAK 532
E +V++L+GLP++ S D++ F I G+ + G+ G+AFV+ + D K
Sbjct: 9 EGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVK 68
Query: 533 LAKELNGNKIAHRYIEVFDSNIEE 604
+A + + + HRYIEVF S+ E
Sbjct: 69 MALKKDRESMGHRYIEVFKSHRTE 92
Score = 52.0 bits (123), Expect = 2e-06
Identities = 27/74 (36%), Positives = 44/74 (59%)
Frame = +2
Query: 365 YVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKE 544
+ + ++GLPY A++ DI FF L P + I + +G+ G+A V+FAT+ +A A
Sbjct: 289 HCVHMRGLPYKATENDIYNFFSPLN--PVRVHIEIGPDGRVTGEADVEFATHEEAVAAMS 346
Query: 545 LNGNKIAHRYIEVF 586
+ + HRYIE+F
Sbjct: 347 KDRANMQHRYIELF 360
Score = 41.6 bits (96), Expect = 0.003
Identities = 24/74 (32%), Positives = 35/74 (47%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196
V +RG+PY+ T +DI F + +H I GEA +E T E+ A
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLN----PVRVHIEIGPDGRVTGEADVEFATHEEAVAAMS 346
Query: 197 RHNQHMGRRYIEVF 238
+ +M RYIE+F
Sbjct: 347 KDRANMQHRYIELF 360
>sp|Q60HC3|HNRPF_MACFA Heterogeneous nuclear ribonucleoprotein F (hnRNP F)
Length = 415
Score = 132 bits (331), Expect = 1e-30
Identities = 79/214 (36%), Positives = 122/214 (57%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196
VKLRG+P+ +++D+ FL TI G G+HF ++ + GEAF+EL +E+D+ A
Sbjct: 13 VKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALK 72
Query: 197 RHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXINENYVLR 376
+ + MG RYIEVF + +M V+ +G N+ +V R
Sbjct: 73 KDRESMGHRYIEVFKSHR-------TEMDWVLKHSGPNSADSA----------NDGFV-R 114
Query: 377 LKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKELNGN 556
L+GLP+ +K +I +FF GL+I+P+G+++ VD GK G+AFVQFA+ A+ A +
Sbjct: 115 LRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKE 174
Query: 557 KIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKR 658
+I HRYIEVF S+ EE + ++F M V+R
Sbjct: 175 RIGHRYIEVFKSSQEEVRSYSDPPLKF--MSVQR 206
Score = 61.2 bits (147), Expect = 3e-09
Identities = 31/91 (34%), Positives = 54/91 (59%)
Frame = +2
Query: 14 WVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAK 193
+V+LRG+P+ T ++I++F G+ I GI P+ GEAF++ ++E KA
Sbjct: 112 FVRLRGLPFGCTKEEIVQFFSGLEIV--PNGITLPVDPEGKITGEAFVQFASQELAEKAL 169
Query: 194 DRHNQHMGRRYIEVFSCTKGDMVKACKDMPV 286
+H + +G RYIEVF ++ + V++ D P+
Sbjct: 170 GKHKERIGHRYIEVFKSSQ-EEVRSYSDPPL 199
Score = 55.5 bits (132), Expect = 2e-07
Identities = 28/84 (33%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
Frame = +2
Query: 359 ENYVLRLKGLPYNASKADIKEFFQGLKILPD--GMSILVDHNGKALGDAFVQFATYHDAK 532
E +V++L+GLP++ S D++ F I G+ + G+ G+AFV+ + D K
Sbjct: 9 EGFVVKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVK 68
Query: 533 LAKELNGNKIAHRYIEVFDSNIEE 604
+A + + + HRYIEVF S+ E
Sbjct: 69 MALKKDRESMGHRYIEVFKSHRTE 92
Score = 52.0 bits (123), Expect = 2e-06
Identities = 27/74 (36%), Positives = 44/74 (59%)
Frame = +2
Query: 365 YVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKE 544
+ + ++GLPY A++ DI FF L P + I + +G+ G+A V+FAT+ +A A
Sbjct: 289 HCVHMRGLPYKATENDIYNFFSPLN--PVRVHIEIGPDGRVTGEADVEFATHEEAVAAMS 346
Query: 545 LNGNKIAHRYIEVF 586
+ + HRYIE+F
Sbjct: 347 KDRANMQHRYIELF 360
Score = 41.6 bits (96), Expect = 0.003
Identities = 24/74 (32%), Positives = 35/74 (47%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196
V +RG+PY+ T +DI F + +H I GEA +E T E+ A
Sbjct: 291 VHMRGLPYKATENDIYNFFSPLN----PVRVHIEIGPDGRVTGEADVEFATHEEAVAAMS 346
Query: 197 RHNQHMGRRYIEVF 238
+ +M RYIE+F
Sbjct: 347 KDRANMQHRYIELF 360
>sp|P70333|HNRH2_MOUSE Heterogeneous nuclear ribonucleoprotein H' (hnRNP H')
Length = 449
Score = 130 bits (326), Expect = 5e-30
Identities = 78/239 (32%), Positives = 127/239 (53%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196
VK+RG+P+ + ++++ F I+ G G+ F ++ GEAF+ELE+E+++ A
Sbjct: 13 VKVRGLPWSCSAEEVMRFFSDCKIQNGTSGVRFIYTREGRPSGEAFVELESEDEVKLALK 72
Query: 197 RHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXINENYVLR 376
+ + MG RY+EVF K + V +M V+ G N+ +V R
Sbjct: 73 KDRETMGHRYVEVF---KSNSV----EMDWVLKHTGPNSPDTA----------NDGFV-R 114
Query: 377 LKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKELNGN 556
L+GLP+ SK +I +FF GL+I+P+GM++ VD G++ G+AFVQFA+ A+ A + +
Sbjct: 115 LRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKE 174
Query: 557 KIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPPQSRGPRSMDDGMAYQESQR 733
+I HRYIE+F S+ E T + M P RG S+ G ++ +R
Sbjct: 175 RIGHRYIEIFKSSRAEVRTHYDPPRKLMTMQRPGPYDRPGAGRGYNSIGRGAGFERMRR 233
Score = 58.9 bits (141), Expect = 2e-08
Identities = 25/82 (30%), Positives = 50/82 (60%)
Frame = +2
Query: 14 WVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAK 193
+V+LRG+P+ + ++I++F G+ I G+ P+ + GEAF++ ++E KA
Sbjct: 112 FVRLRGLPFGCSKEEIVQFFSGLEIV--PNGMTLPVDFQGRSTGEAFVQFASQEIAEKAL 169
Query: 194 DRHNQHMGRRYIEVFSCTKGDM 259
+H + +G RYIE+F ++ ++
Sbjct: 170 KKHKERIGHRYIEIFKSSRAEV 191
Score = 57.8 bits (138), Expect = 3e-08
Identities = 28/84 (33%), Positives = 48/84 (57%), Gaps = 2/84 (2%)
Frame = +2
Query: 359 ENYVLRLKGLPYNASKADIKEFFQGLKIL--PDGMSILVDHNGKALGDAFVQFATYHDAK 532
E +V++++GLP++ S ++ FF KI G+ + G+ G+AFV+ + + K
Sbjct: 9 EGFVVKVRGLPWSCSAEEVMRFFSDCKIQNGTSGVRFIYTREGRPSGEAFVELESEDEVK 68
Query: 533 LAKELNGNKIAHRYIEVFDSNIEE 604
LA + + + HRY+EVF SN E
Sbjct: 69 LALKKDRETMGHRYVEVFKSNSVE 92
Score = 52.8 bits (125), Expect = 1e-06
Identities = 27/74 (36%), Positives = 44/74 (59%)
Frame = +2
Query: 365 YVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKE 544
+ + ++GLPY A++ DI FF L P + I + +G+ G+A V+FAT+ DA A
Sbjct: 289 HCVHMRGLPYRATENDIYNFFSPLN--PMRVHIEIGPDGRVTGEADVEFATHEDAVAAMA 346
Query: 545 LNGNKIAHRYIEVF 586
+ + HRY+E+F
Sbjct: 347 KDKANMQHRYVELF 360
Score = 43.9 bits (102), Expect = 5e-04
Identities = 25/74 (33%), Positives = 35/74 (47%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196
V +RG+PYR T +DI F + +H I GEA +E T ED A
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLN----PMRVHIEIGPDGRVTGEADVEFATHEDAVAAMA 346
Query: 197 RHNQHMGRRYIEVF 238
+ +M RY+E+F
Sbjct: 347 KDKANMQHRYVELF 360
>sp|O35737|HNRH1_MOUSE Heterogeneous nuclear ribonucleoprotein H (hnRNP H)
Length = 449
Score = 129 bits (323), Expect = 1e-29
Identities = 77/239 (32%), Positives = 124/239 (51%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196
VK+RG+P+ + D++ F I+ G +GI F ++ GEAF+ELE+E+++ A
Sbjct: 13 VKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALK 72
Query: 197 RHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXINENYVLR 376
+ + MG RY+EVF +M V+ G N+ +V R
Sbjct: 73 KDRETMGHRYVEVFKSNN-------VEMDWVLKHTGPNSPDTA----------NDGFV-R 114
Query: 377 LKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKELNGN 556
L+GLP+ SK +I +FF GL+I+P+G+++ VD G++ G+AFVQFA+ A+ A + +
Sbjct: 115 LRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKE 174
Query: 557 KIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPPQSRGPRSMDDGMAYQESQR 733
+I HRYIE+F S+ E T + M P RG S+ G ++ +R
Sbjct: 175 RIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRR 233
Score = 60.1 bits (144), Expect = 7e-09
Identities = 26/82 (31%), Positives = 50/82 (60%)
Frame = +2
Query: 14 WVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAK 193
+V+LRG+P+ + ++I++F G+ I GI P+ + GEAF++ ++E KA
Sbjct: 112 FVRLRGLPFGCSKEEIVQFFSGLEIV--PNGITLPVDFQGRSTGEAFVQFASQEIAEKAL 169
Query: 194 DRHNQHMGRRYIEVFSCTKGDM 259
+H + +G RYIE+F ++ ++
Sbjct: 170 KKHKERIGHRYIEIFKSSRAEV 191
Score = 57.8 bits (138), Expect = 3e-08
Identities = 27/81 (33%), Positives = 48/81 (59%), Gaps = 2/81 (2%)
Frame = +2
Query: 359 ENYVLRLKGLPYNASKADIKEFFQGLKIL--PDGMSILVDHNGKALGDAFVQFATYHDAK 532
E +V++++GLP++ S +++ FF KI G+ + G+ G+AFV+ + + K
Sbjct: 9 EGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVK 68
Query: 533 LAKELNGNKIAHRYIEVFDSN 595
LA + + + HRY+EVF SN
Sbjct: 69 LALKKDRETMGHRYVEVFKSN 89
Score = 53.1 bits (126), Expect = 9e-07
Identities = 27/74 (36%), Positives = 44/74 (59%)
Frame = +2
Query: 365 YVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKE 544
+ + ++GLPY A++ DI FF L P + I + +G+ G+A V+FAT+ DA A
Sbjct: 289 HCVHMRGLPYRATENDIYNFFSPLN--PVRVHIEIGPDGRVTGEADVEFATHEDAVAAMS 346
Query: 545 LNGNKIAHRYIEVF 586
+ + HRY+E+F
Sbjct: 347 KDKANMQHRYVELF 360
Score = 43.9 bits (102), Expect = 5e-04
Identities = 25/74 (33%), Positives = 35/74 (47%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196
V +RG+PYR T +DI F + +H I GEA +E T ED A
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLN----PVRVHIEIGPDGRVTGEADVEFATHEDAVAAMS 346
Query: 197 RHNQHMGRRYIEVF 238
+ +M RY+E+F
Sbjct: 347 KDKANMQHRYVELF 360
>sp|P31943|HNRH1_HUMAN Heterogeneous nuclear ribonucleoprotein H (hnRNP H)
Length = 449
Score = 129 bits (323), Expect = 1e-29
Identities = 77/239 (32%), Positives = 124/239 (51%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196
VK+RG+P+ + D++ F I+ G +GI F ++ GEAF+ELE+E+++ A
Sbjct: 13 VKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALK 72
Query: 197 RHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXINENYVLR 376
+ + MG RY+EVF +M V+ G N+ +V R
Sbjct: 73 KDRETMGHRYVEVFKSNN-------VEMDWVLKHTGPNSPDTA----------NDGFV-R 114
Query: 377 LKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKELNGN 556
L+GLP+ SK +I +FF GL+I+P+G+++ VD G++ G+AFVQFA+ A+ A + +
Sbjct: 115 LRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKE 174
Query: 557 KIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPPQSRGPRSMDDGMAYQESQR 733
+I HRYIE+F S+ E T + M P RG S+ G ++ +R
Sbjct: 175 RIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRR 233
Score = 60.1 bits (144), Expect = 7e-09
Identities = 26/82 (31%), Positives = 50/82 (60%)
Frame = +2
Query: 14 WVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAK 193
+V+LRG+P+ + ++I++F G+ I GI P+ + GEAF++ ++E KA
Sbjct: 112 FVRLRGLPFGCSKEEIVQFFSGLEIV--PNGITLPVDFQGRSTGEAFVQFASQEIAEKAL 169
Query: 194 DRHNQHMGRRYIEVFSCTKGDM 259
+H + +G RYIE+F ++ ++
Sbjct: 170 KKHKERIGHRYIEIFKSSRAEV 191
Score = 57.8 bits (138), Expect = 3e-08
Identities = 27/81 (33%), Positives = 48/81 (59%), Gaps = 2/81 (2%)
Frame = +2
Query: 359 ENYVLRLKGLPYNASKADIKEFFQGLKIL--PDGMSILVDHNGKALGDAFVQFATYHDAK 532
E +V++++GLP++ S +++ FF KI G+ + G+ G+AFV+ + + K
Sbjct: 9 EGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVK 68
Query: 533 LAKELNGNKIAHRYIEVFDSN 595
LA + + + HRY+EVF SN
Sbjct: 69 LALKKDRETMGHRYVEVFKSN 89
Score = 53.1 bits (126), Expect = 9e-07
Identities = 27/74 (36%), Positives = 44/74 (59%)
Frame = +2
Query: 365 YVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKE 544
+ + ++GLPY A++ DI FF L P + I + +G+ G+A V+FAT+ DA A
Sbjct: 289 HCVHMRGLPYRATENDIYNFFSPLN--PVRVHIEIGPDGRVTGEADVEFATHEDAVAAMS 346
Query: 545 LNGNKIAHRYIEVF 586
+ + HRY+E+F
Sbjct: 347 KDKANMQHRYVELF 360
Score = 43.9 bits (102), Expect = 5e-04
Identities = 25/74 (33%), Positives = 35/74 (47%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAKD 196
V +RG+PYR T +DI F + +H I GEA +E T ED A
Sbjct: 291 VHMRGLPYRATENDIYNFFSPLN----PVRVHIEIGPDGRVTGEADVEFATHEDAVAAMS 346
Query: 197 RHNQHMGRRYIEVF 238
+ +M RY+E+F
Sbjct: 347 KDKANMQHRYVELF 360
>sp|Q12849|GRSF1_HUMAN G-rich sequence factor 1 (GRSF-1)
Length = 447
Score = 117 bits (294), Expect = 3e-26
Identities = 66/208 (31%), Positives = 114/208 (54%), Gaps = 5/208 (2%)
Frame = +2
Query: 11 YWVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKA 190
+ ++ +G+P+ TM+D++ F I+ G+ GIHF +++ G+A IE+E+E+D+ KA
Sbjct: 117 FLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQDVQKA 176
Query: 191 KDRHNQHMGRRYIEVFSCTKGDMVKACKDMPV----VVNENGXXXXXXXXXXXXXXXXIN 358
++H +MG+RY+EV+ D+ K + V VVN+
Sbjct: 177 LEKHRMYMGQRYVEVYEINNEDVDALMKSLQVKSSPVVNDG------------------- 217
Query: 359 ENYVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNG-KALGDAFVQFATYHDAKL 535
V+RL+GLPY+ ++ DI +FF GL I+ ++ ++D+ G + G+A+VQF A
Sbjct: 218 ---VVRLRGLPYSCNEKDIVDFFAGLNIV--DITFVMDYRGRRKTGEAYVQFEEPEMANQ 272
Query: 536 AKELNGNKIAHRYIEVFDSNIEEANTEI 619
A + +I +RYIE+F S E T +
Sbjct: 273 ALLKHREEIGNRYIEIFPSRRNEVRTHV 300
Score = 74.7 bits (182), Expect = 3e-13
Identities = 60/227 (26%), Positives = 98/227 (43%), Gaps = 37/227 (16%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNI-EWGEAFIELETEEDLNKAK 193
V+LRG+PY DI++F G+ I I F + R + GEA+++ E E N+A
Sbjct: 219 VRLRGLPYSCNEKDIVDFFAGLNIVD----ITFVMDYRGRRKTGEAYVQFEEPEMANQAL 274
Query: 194 DRHNQHMGRRYIEVFSCTKGDM-----------------VKACKDMPVVVNENGXXXXXX 322
+H + +G RYIE+F + ++ K + +V E+
Sbjct: 275 LKHREEIGNRYIEIFPSRRNEVRTHVGSYKGKKIASFPTAKYITEPEMVFEEHEVNEDIQ 334
Query: 323 XXXXXXXXXXI-------------------NENYVLRLKGLPYNASKADIKEFFQGLKIL 445
I + + + ++GLP+ A+ DI FF LK
Sbjct: 335 PMTAFESEKEIELPKEVPEKLPEAADFGTTSSLHFVHMRGLPFQANAQDIINFFAPLK-- 392
Query: 446 PDGMSILVDHNGKALGDAFVQFATYHDAKLAKELNGNKIAHRYIEVF 586
P +++ +GKA G+A V F T+ DA A + + + HRYIE+F
Sbjct: 393 PVRITMEYSSSGKATGEADVHFETHEDAVAAMLKDRSHVHHRYIELF 439
Score = 52.8 bits (125), Expect = 1e-06
Identities = 24/88 (27%), Positives = 52/88 (59%), Gaps = 2/88 (2%)
Frame = +2
Query: 353 INENYVLRLKGLPYNASKADIKEFFQGLKIL--PDGMSILVDHNGKALGDAFVQFATYHD 526
+++ +++R +GLP++ + D+ FF +I +G+ L++ +GK GDA ++ + D
Sbjct: 113 VDDVFLIRAQGLPWSCTMEDVLNFFSDCRIRNGENGIHFLLNRDGKRRGDALIEMESEQD 172
Query: 527 AKLAKELNGNKIAHRYIEVFDSNIEEAN 610
+ A E + + RY+EV++ N E+ +
Sbjct: 173 VQKALEKHRMYMGQRYVEVYEINNEDVD 200
Score = 43.9 bits (102), Expect = 5e-04
Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
Frame = +2
Query: 5 SEYWVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLN 184
S ++V +RG+P++ DII F + I S GEA + ET ED
Sbjct: 366 SLHFVHMRGLPFQANAQDIINFFAPLK----PVRITMEYSSSGKATGEADVHFETHEDAV 421
Query: 185 KAKDRHNQHMGRRYIEVF--SCTKG 253
A + H+ RYIE+F SC KG
Sbjct: 422 AAMLKDRSHVHHRYIELFLNSCPKG 446
>sp|Q8C5Q4|GRSF1_MOUSE G-rich sequence factor 1 (GRSF-1)
Length = 479
Score = 114 bits (285), Expect = 3e-25
Identities = 62/204 (30%), Positives = 111/204 (54%), Gaps = 1/204 (0%)
Frame = +2
Query: 11 YWVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKA 190
Y ++ +G+P+ T++D++ F I+ + GIHF +++ G+A IE+E+E+D+ KA
Sbjct: 149 YLIRAQGLPWSCTVEDVLNFFSDCRIRNSENGIHFLLNRDGKRRGDALIEMESEQDVQKA 208
Query: 191 KDRHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXINENYV 370
++H +MG+RY+EV+ D+ K + V + + V
Sbjct: 209 LEKHRMYMGQRYVEVYEINNEDVDALMKSLQV------------------KPSPVLSDGV 250
Query: 371 LRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNG-KALGDAFVQFATYHDAKLAKEL 547
+RL+GLPY+ ++ DI +FF GL I+ ++ ++D+ G + G+A+VQF A A
Sbjct: 251 VRLRGLPYSCNEKDIVDFFAGLNIV--DITFVMDYRGRRKTGEAYVQFEEPEMANQALLK 308
Query: 548 NGNKIAHRYIEVFDSNIEEANTEI 619
+ +I +RYIE+F S E T +
Sbjct: 309 HREEIGNRYIEIFPSRRNEVRTHV 332
Score = 76.3 bits (186), Expect = 9e-14
Identities = 62/232 (26%), Positives = 100/232 (43%), Gaps = 37/232 (15%)
Frame = +2
Query: 2 MSEYWVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQR-NIEWGEAFIELETEED 178
+S+ V+LRG+PY DI++F G+ I I F + R + GEA+++ E E
Sbjct: 246 LSDGVVRLRGLPYSCNEKDIVDFFAGLNIV----DITFVMDYRGRRKTGEAYVQFEEPEM 301
Query: 179 LNKAKDRHNQHMGRRYIEVFSCTKGDM-----------------VKACKDMPVVVNENGX 307
N+A +H + +G RYIE+F + ++ K + VV E+
Sbjct: 302 ANQALLKHREEIGNRYIEIFPSRRNEVRTHVGSHKGKKMTSSPPTKYITEPEVVFEEHEV 361
Query: 308 XXXXXXXXXXXXXXXIN-------------------ENYVLRLKGLPYNASKADIKEFFQ 430
I + + ++GLP+ A+ DI FF
Sbjct: 362 NEDIRPMTAFESDKEIELPKEMSEKLPEAVDFGTLPSLHFVHMRGLPFQANAQDIINFFA 421
Query: 431 GLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKELNGNKIAHRYIEVF 586
LK P +++ +GKA G+A V F T+ DA A + + + HRYIE+F
Sbjct: 422 PLK--PVRITMEYSSSGKATGEADVHFDTHEDAVAAMLKDRSHVQHRYIELF 471
Score = 53.9 bits (128), Expect = 5e-07
Identities = 25/88 (28%), Positives = 52/88 (59%), Gaps = 2/88 (2%)
Frame = +2
Query: 353 INENYVLRLKGLPYNASKADIKEFFQGLKI--LPDGMSILVDHNGKALGDAFVQFATYHD 526
+++ Y++R +GLP++ + D+ FF +I +G+ L++ +GK GDA ++ + D
Sbjct: 145 VDDVYLIRAQGLPWSCTVEDVLNFFSDCRIRNSENGIHFLLNRDGKRRGDALIEMESEQD 204
Query: 527 AKLAKELNGNKIAHRYIEVFDSNIEEAN 610
+ A E + + RY+EV++ N E+ +
Sbjct: 205 VQKALEKHRMYMGQRYVEVYEINNEDVD 232
Score = 42.7 bits (99), Expect = 0.001
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
Frame = +2
Query: 5 SEYWVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLN 184
S ++V +RG+P++ DII F + I S GEA + +T ED
Sbjct: 398 SLHFVHMRGLPFQANAQDIINFFAPLK----PVRITMEYSSSGKATGEADVHFDTHEDAV 453
Query: 185 KAKDRHNQHMGRRYIEVF--SCTKG 253
A + H+ RYIE+F SC KG
Sbjct: 454 AAMLKDRSHVQHRYIELFLNSCPKG 478
>sp|Q9NTZ6|RBM12_HUMAN RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain
anchor protein in the nucleus) (SWAN)
Length = 932
Score = 79.7 bits (195), Expect = 8e-15
Identities = 55/223 (24%), Positives = 99/223 (44%), Gaps = 1/223 (0%)
Frame = +2
Query: 11 YWVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKA 190
+ V L+G+P+ +I+F + I + I+ GE F+E E D A
Sbjct: 430 FCVYLKGLPFEAENKHVIDFFKKLDIV--EDSIYIAYGPNGKATGEGFVEFRNEADYKAA 487
Query: 191 KDRHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXINENYV 370
RH Q+MG R+I+V TK M++ + ++ +N V
Sbjct: 488 LCRHKQYMGNRFIQVHPITKKGMLEK---IDMIRKRLQNFSYDQREMILNPEGDVNSAKV 544
Query: 371 L-RLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKEL 547
+ +P++ +K D+ +F +G+ + + + +LVD+NG+ LG A VQF DA+ ++ L
Sbjct: 545 CAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERL 604
Query: 548 NGNKIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPP 676
+ K+ R V +E+ ++ EK+PP
Sbjct: 605 HRKKLNGREAFVHVVTLED---------------MREIEKNPP 632
Score = 59.7 bits (143), Expect = 9e-09
Identities = 47/204 (23%), Positives = 83/204 (40%), Gaps = 12/204 (5%)
Frame = +2
Query: 8 EYWVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNK 187
+ +V + GMP+ +D+ +F G+ + +H G ++ + +D +
Sbjct: 303 DLYVSVHGMPFSAMENDVRDFFHGLRVDA----VHLLKDHVGRNNGNGLVKFLSPQDTFE 358
Query: 188 AKDRHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXIN--- 358
A R+ M +RY+EV T+ V A + N +
Sbjct: 359 ALKRNRMLMIQRYVEVSPATERQWVAAGGHITFKQNMGPSGQTHPPPQTLPRSKSPSGQK 418
Query: 359 ---------ENYVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQF 511
+ + LKGLP+ A + +FF+ L I+ D + I NGKA G+ FV+F
Sbjct: 419 RSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEF 478
Query: 512 ATYHDAKLAKELNGNKIAHRYIEV 583
D K A + + +R+I+V
Sbjct: 479 RNEADYKAALCRHKQYMGNRFIQV 502
Score = 53.5 bits (127), Expect = 7e-07
Identities = 41/116 (35%), Positives = 56/116 (48%), Gaps = 6/116 (5%)
Frame = +2
Query: 368 VLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKEL 547
V+RL+GLP A DI+ FF GL I G+ I+ G LG+AF+ FAT DA+L
Sbjct: 4 VIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIV----GGELGEAFIVFATDEDARLGMMR 59
Query: 548 NGNKIAHRYIEVFDSNIEEANTEI---RRQMEFNDMHVKRYEKS---PPQSRGPRS 697
G I + + S+ E I RR+ E ++ + S PP S G S
Sbjct: 60 TGGTIKGSKVTLLLSSKTEMQNMIELSRRRFETANLDIPPANASRSGPPPSSGMSS 115
Score = 48.1 bits (113), Expect = 3e-05
Identities = 23/75 (30%), Positives = 45/75 (60%)
Frame = +2
Query: 359 ENYVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLA 538
++ + + G+P++A + D+++FF GL++ D + +L DH G+ G+ V+F + D A
Sbjct: 302 DDLYVSVHGMPFSAMENDVRDFFHGLRV--DAVHLLKDHVGRNNGNGLVKFLSPQDTFEA 359
Query: 539 KELNGNKIAHRYIEV 583
+ N + RY+EV
Sbjct: 360 LKRNRMLMIQRYVEV 374
Score = 39.7 bits (91), Expect = 0.010
Identities = 19/73 (26%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
Frame = +2
Query: 368 VLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAK-E 544
V++++ +P+ S +I +FF G +++P + + + G G+A V F + +A A +
Sbjct: 857 VIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVID 916
Query: 545 LNGNKIAHRYIEV 583
LN I R +++
Sbjct: 917 LNDRPIGSRKVKL 929
Score = 33.5 bits (75), Expect = 0.70
Identities = 16/74 (21%), Positives = 42/74 (56%), Gaps = 1/74 (1%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAK- 193
+K++ MP+ ++D+I++F G + G + +++ + GEA + E+ ++ A
Sbjct: 858 IKVQNMPFTVSIDEILDFFYGYQVIPG--SVCLKYNEKGMPTGEAMVAFESRDEATAAVI 915
Query: 194 DRHNQHMGRRYIEV 235
D +++ +G R +++
Sbjct: 916 DLNDRPIGSRKVKL 929
Score = 33.1 bits (74), Expect = 0.91
Identities = 21/54 (38%), Positives = 28/54 (51%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEED 178
++L+G+P DI F G+TI G G+H E GEAFI T+ED
Sbjct: 5 IRLQGLPIVAGTMDIRHFFSGLTIPDG--GVHIV----GGELGEAFIVFATDED 52
>sp|Q8SQ27|RBM12_MACMU RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain
anchor protein in the nucleus) (SWAN)
Length = 932
Score = 79.7 bits (195), Expect = 8e-15
Identities = 55/223 (24%), Positives = 99/223 (44%), Gaps = 1/223 (0%)
Frame = +2
Query: 11 YWVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKA 190
+ V L+G+P+ +I+F + I + I+ GE F+E E D A
Sbjct: 430 FCVYLKGLPFEAENKHVIDFFKKLDIV--EDSIYIAYGPNGKATGEGFVEFRNEADYKAA 487
Query: 191 KDRHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXINENYV 370
RH Q+MG R+I+V TK M++ + ++ +N V
Sbjct: 488 LCRHKQYMGNRFIQVHPITKKGMLEK---IDMIRKRLQNFSYDQREMMLNPEGDVNSAKV 544
Query: 371 L-RLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKEL 547
+ +P++ +K D+ +F +G+ + + + +LVD+NG+ LG A VQF DA+ ++ L
Sbjct: 545 CAHITNIPFSITKMDVLQFLEGIPVDENAVHVLVDNNGQGLGQALVQFKNEDDARKSERL 604
Query: 548 NGNKIAHRYIEVFDSNIEEANTEIRRQMEFNDMHVKRYEKSPP 676
+ K+ R V +E+ ++ EK+PP
Sbjct: 605 HRKKLNGREAFVHVVTLED---------------MREIEKNPP 632
Score = 59.7 bits (143), Expect = 9e-09
Identities = 47/204 (23%), Positives = 83/204 (40%), Gaps = 12/204 (5%)
Frame = +2
Query: 8 EYWVKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNK 187
+ +V + GMP+ +D+ +F G+ + +H G ++ + +D +
Sbjct: 303 DLYVSVHGMPFSAMENDVRDFFHGLRVDA----VHLLKDHVGRNNGNGLVKFLSPQDTFE 358
Query: 188 AKDRHNQHMGRRYIEVFSCTKGDMVKACKDMPVVVNENGXXXXXXXXXXXXXXXXIN--- 358
A R+ M +RY+EV T+ V A + N +
Sbjct: 359 ALKRNRMLMIQRYVEVSPATERQWVAAGGHITFKQNMGPSGQSHPPPQTLPRSKSPSGQK 418
Query: 359 ---------ENYVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQF 511
+ + LKGLP+ A + +FF+ L I+ D + I NGKA G+ FV+F
Sbjct: 419 RSRSRSPHEAGFCVYLKGLPFEAENKHVIDFFKKLDIVEDSIYIAYGPNGKATGEGFVEF 478
Query: 512 ATYHDAKLAKELNGNKIAHRYIEV 583
D K A + + +R+I+V
Sbjct: 479 RNEADYKAALCRHKQYMGNRFIQV 502
Score = 53.1 bits (126), Expect = 9e-07
Identities = 40/113 (35%), Positives = 55/113 (48%), Gaps = 6/113 (5%)
Frame = +2
Query: 368 VLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAKEL 547
V+RL+GLP A DI+ FF GL I G+ I+ G LG+AF+ FAT DA+L
Sbjct: 4 VIRLQGLPIVAGTMDIRHFFSGLTIPDGGVHIV----GGELGEAFIVFATDEDARLGMMR 59
Query: 548 NGNKIAHRYIEVFDSNIEEANTEI---RRQMEFNDMHVKRYEKS---PPQSRG 688
G I + + S+ E I RR+ E ++ + S PP S G
Sbjct: 60 TGGTIKGSKVTLLLSSKTEMQNMIELSRRRFETANLDIPPANASRSGPPPSSG 112
Score = 48.1 bits (113), Expect = 3e-05
Identities = 23/75 (30%), Positives = 45/75 (60%)
Frame = +2
Query: 359 ENYVLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLA 538
++ + + G+P++A + D+++FF GL++ D + +L DH G+ G+ V+F + D A
Sbjct: 302 DDLYVSVHGMPFSAMENDVRDFFHGLRV--DAVHLLKDHVGRNNGNGLVKFLSPQDTFEA 359
Query: 539 KELNGNKIAHRYIEV 583
+ N + RY+EV
Sbjct: 360 LKRNRMLMIQRYVEV 374
Score = 39.7 bits (91), Expect = 0.010
Identities = 19/73 (26%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
Frame = +2
Query: 368 VLRLKGLPYNASKADIKEFFQGLKILPDGMSILVDHNGKALGDAFVQFATYHDAKLAK-E 544
V++++ +P+ S +I +FF G +++P + + + G G+A V F + +A A +
Sbjct: 857 VIKVQNMPFTVSIDEILDFFYGYQVIPGSVCLKYNEKGMPTGEAMVAFESRDEATAAVID 916
Query: 545 LNGNKIAHRYIEV 583
LN I R +++
Sbjct: 917 LNDRPIGSRKVKL 929
Score = 33.5 bits (75), Expect = 0.70
Identities = 16/74 (21%), Positives = 42/74 (56%), Gaps = 1/74 (1%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEEDLNKAK- 193
+K++ MP+ ++D+I++F G + G + +++ + GEA + E+ ++ A
Sbjct: 858 IKVQNMPFTVSIDEILDFFYGYQVIPG--SVCLKYNEKGMPTGEAMVAFESRDEATAAVI 915
Query: 194 DRHNQHMGRRYIEV 235
D +++ +G R +++
Sbjct: 916 DLNDRPIGSRKVKL 929
Score = 33.1 bits (74), Expect = 0.91
Identities = 21/54 (38%), Positives = 28/54 (51%)
Frame = +2
Query: 17 VKLRGMPYRTTMDDIIEFLPGITIKGGKRGIHFPISQRNIEWGEAFIELETEED 178
++L+G+P DI F G+TI G G+H E GEAFI T+ED
Sbjct: 5 IRLQGLPIVAGTMDIRHFFSGLTIPDG--GVHIV----GGELGEAFIVFATDED 52
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,733,157
Number of Sequences: 369166
Number of extensions: 1570002
Number of successful extensions: 4472
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4233
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4399
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7618580670
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)