Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00930 (493 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P35479|CPI1_PIG Leukocyte cysteine proteinase inhibitor ... 79 6e-15 sp|P01040|CYTA_HUMAN Cystatin A (Stefin A) (Cystatin AS) 76 5e-14 sp|Q28988|CYTA1_PIG Cystatin A1 (Stefin A1) 73 4e-13 sp|Q8I030|CYTB_PANTR Cystatin B (Stefin B) 72 9e-13 sp|Q28986|CYTA5_PIG Cystatin A5 (Stefin A5) 72 9e-13 sp|Q862Z5|CYTB_MACFU Cystatin B (Stefin B) 71 1e-12 sp|Q28987|CYTA8_PIG Cystatin A8 (Stefin A8) 71 1e-12 sp|P60576|CYTB_PONPY Cystatin B (Stefin B) >gi|45476793|sp|... 71 2e-12 sp|P01041|CYTB_RAT Cystatin B (Liver thiol proteinase inhib... 70 3e-12 sp|P80416|CYTA_BOVIN Cystatin A (Stefin A) (Cystatin AS) 69 8e-12
>sp|P35479|CPI1_PIG Leukocyte cysteine proteinase inhibitor 1 (PLCPI) (Stefin D1) Length = 103 Score = 79.0 bits (193), Expect = 6e-15 Identities = 45/98 (45%), Positives = 60/98 (61%), Gaps = 2/98 (2%) Frame = +1 Query: 61 MLCGGTGNVRTPSEEEKTILLTVKPQIEDQIGHSCSAFDILQLRSQVVAGTNYFAKVHIG 240 ML GG R + E + I VKPQ+E++ + F+ + RSQVVAGTNY+ KVH+G Sbjct: 6 MLAGGLTEPRPATPEIQEIANKVKPQLEEKTNKTYEKFEAIIYRSQVVAGTNYYIKVHVG 65 Query: 241 DGKHIHIRVYQPLPGQGD-LALHGLQ-EKLKEDVLEYF 348 ++HIRV+Q LP Q D L L G Q +K K+D L F Sbjct: 66 GNNYVHIRVFQSLPHQEDPLKLIGYQVDKTKDDELTGF 103
>sp|P01040|CYTA_HUMAN Cystatin A (Stefin A) (Cystatin AS) Length = 98 Score = 75.9 bits (185), Expect = 5e-14 Identities = 40/98 (40%), Positives = 62/98 (63%), Gaps = 2/98 (2%) Frame = +1 Query: 61 MLCGGTGNVRTPSEEEKTILLTVKPQIEDQIGHSCSAFDILQLRSQVVAGTNYFAKVHIG 240 M+ GG + + E + I+ VKPQ+E++ + + +Q ++QVVAGTNY+ KV G Sbjct: 1 MIPGGLSEAKPATPEIQEIVDKVKPQLEEKTNETYGKLEAVQYKTQVVAGTNYYIKVRAG 60 Query: 241 DGKHIHIRVYQPLPGQG-DLALHGLQ-EKLKEDVLEYF 348 D K++H++V++ LPGQ DL L G Q +K K+D L F Sbjct: 61 DNKYMHLKVFKSLPGQNEDLVLTGYQVDKNKDDELTGF 98
>sp|Q28988|CYTA1_PIG Cystatin A1 (Stefin A1) Length = 103 Score = 72.8 bits (177), Expect = 4e-13 Identities = 39/100 (39%), Positives = 61/100 (61%), Gaps = 2/100 (2%) Frame = +1 Query: 55 NRMLCGGTGNVRTPSEEEKTILLTVKPQIEDQIGHSCSAFDILQLRSQVVAGTNYFAKVH 234 ++M+ GG R + E + I TVK Q+E++ + F+ ++ +SQVVAG NY+ KVH Sbjct: 4 DKMMPGGLTEARPATPEIQEIATTVKSQLEEKTNKTYEKFEAVEYKSQVVAGINYYIKVH 63 Query: 235 IGDGKHIHIRVYQPLPGQG-DLALHGLQ-EKLKEDVLEYF 348 +G ++HI+V++ LP Q L L G Q +K K+D L F Sbjct: 64 VGGNSYVHIKVFKSLPYQNKPLELSGYQVDKTKDDELTGF 103
>sp|Q8I030|CYTB_PANTR Cystatin B (Stefin B) Length = 98 Score = 71.6 bits (174), Expect = 9e-13 Identities = 39/98 (39%), Positives = 55/98 (56%), Gaps = 2/98 (2%) Frame = +1 Query: 61 MLCGGTGNVRTPSEEEKTILLTVKPQIEDQIGHSCSAFDILQLRSQVVAGTNYFAKVHIG 240 M+CG + + E + I V+ Q+E++ F + +SQVVAGTNYF KVH+G Sbjct: 1 MMCGAPSATQPATAETQHIADQVRSQLEEKENKKFPVFKAVSFKSQVVAGTNYFIKVHVG 60 Query: 241 DGKHIHIRVYQPLPGQG-DLALHGLQ-EKLKEDVLEYF 348 D + +H+RV+Q LP + L L Q K K D L YF Sbjct: 61 DEEFVHLRVFQSLPHENKPLTLSNYQTNKAKHDELTYF 98
>sp|Q28986|CYTA5_PIG Cystatin A5 (Stefin A5) Length = 103 Score = 71.6 bits (174), Expect = 9e-13 Identities = 42/98 (42%), Positives = 58/98 (59%), Gaps = 2/98 (2%) Frame = +1 Query: 61 MLCGGTGNVRTPSEEEKTILLTVKPQIEDQIGHSCSAFDILQLRSQVVAGTNYFAKVHIG 240 ML GG R + E + I VKPQ+E++ + F+ + RSQVVAGTNY+ KVH+G Sbjct: 6 MLAGGLTEPRPATPEIQEIANKVKPQLEEKTKKTYEKFEAIIYRSQVVAGTNYYIKVHVG 65 Query: 241 DGKHIHIRVYQPLPGQGD-LALHGLQ-EKLKEDVLEYF 348 ++HI V+Q LP + L L G Q +K K+D L F Sbjct: 66 GNSYVHIIVFQNLPQLNEPLKLIGYQVDKTKDDELTSF 103
>sp|Q862Z5|CYTB_MACFU Cystatin B (Stefin B) Length = 98 Score = 71.2 bits (173), Expect = 1e-12 Identities = 39/98 (39%), Positives = 55/98 (56%), Gaps = 2/98 (2%) Frame = +1 Query: 61 MLCGGTGNVRTPSEEEKTILLTVKPQIEDQIGHSCSAFDILQLRSQVVAGTNYFAKVHIG 240 M+CG V+ + E + I V+ Q+E++ F + +SQVVAGTNYF KVH+G Sbjct: 1 MMCGAPSAVQPATAETQDIADQVRSQLEEKENKKFPVFKAVSFKSQVVAGTNYFIKVHVG 60 Query: 241 DGKHIHIRVYQPLPGQG-DLALHGLQ-EKLKEDVLEYF 348 D +H+RV++ LP + L L Q K K D L YF Sbjct: 61 DEDFVHLRVFKSLPHENKPLTLSDYQTNKAKHDELSYF 98
>sp|Q28987|CYTA8_PIG Cystatin A8 (Stefin A8) Length = 103 Score = 71.2 bits (173), Expect = 1e-12 Identities = 42/98 (42%), Positives = 58/98 (59%), Gaps = 2/98 (2%) Frame = +1 Query: 61 MLCGGTGNVRTPSEEEKTILLTVKPQIEDQIGHSCSAFDILQLRSQVVAGTNYFAKVHIG 240 ML GG R + E + I VKPQ+E++ + F+ + RSQVVAGTNY+ KVH+G Sbjct: 6 MLAGGLTEPRPATPEIQEIANKVKPQLEEKTKKTYEKFEAIIYRSQVVAGTNYYIKVHVG 65 Query: 241 DGKHIHIRVYQPLPGQGD-LALHGLQ-EKLKEDVLEYF 348 ++HI V+Q LP + L L G Q +K K+D L F Sbjct: 66 GNSYVHIIVFQNLPQLNEPLKLIGYQVDKTKDDELTGF 103
>sp|P60576|CYTB_PONPY Cystatin B (Stefin B) sp|P60575|CYTB_PANPA Cystatin B (Stefin B) sp|Q76LA0|CYTB_GORGO Cystatin B (Stefin B) sp|P04080|CYTB_HUMAN Cystatin B (Liver thiol proteinase inhibitor) (CPI-B) (Stefin B) Length = 98 Score = 70.9 bits (172), Expect = 2e-12 Identities = 39/98 (39%), Positives = 54/98 (55%), Gaps = 2/98 (2%) Frame = +1 Query: 61 MLCGGTGNVRTPSEEEKTILLTVKPQIEDQIGHSCSAFDILQLRSQVVAGTNYFAKVHIG 240 M+CG + + E + I V+ Q+E++ F + +SQVVAGTNYF KVH+G Sbjct: 1 MMCGAPSATQPATAETQHIADQVRSQLEEKENKKFPVFKAVSFKSQVVAGTNYFIKVHVG 60 Query: 241 DGKHIHIRVYQPLPGQG-DLALHGLQ-EKLKEDVLEYF 348 D +H+RV+Q LP + L L Q K K D L YF Sbjct: 61 DEDFVHLRVFQSLPHENKPLTLSNYQTNKAKHDELTYF 98
>sp|P01041|CYTB_RAT Cystatin B (Liver thiol proteinase inhibitor) (Stefin B) (Cystatin beta) Length = 98 Score = 69.7 bits (169), Expect = 3e-12 Identities = 38/98 (38%), Positives = 54/98 (55%), Gaps = 2/98 (2%) Frame = +1 Query: 61 MLCGGTGNVRTPSEEEKTILLTVKPQIEDQIGHSCSAFDILQLRSQVVAGTNYFAKVHIG 240 M+CG + E + I VK Q+E++ F + R QVVAGTN+F KV +G Sbjct: 1 MMCGAPSATMPATTETQEIADKVKSQLEEKANQKFDVFKAISFRRQVVAGTNFFIKVDVG 60 Query: 241 DGKHIHIRVYQPLPGQG-DLALHGLQ-EKLKEDVLEYF 348 + K +H+RV++PLP + L L Q +K K D L YF Sbjct: 61 EEKCVHLRVFEPLPHENKPLTLSSYQTDKEKHDELTYF 98
>sp|P80416|CYTA_BOVIN Cystatin A (Stefin A) (Cystatin AS) Length = 98 Score = 68.6 bits (166), Expect = 8e-12 Identities = 38/98 (38%), Positives = 58/98 (59%), Gaps = 2/98 (2%) Frame = +1 Query: 61 MLCGGTGNVRTPSEEEKTILLTVKPQIEDQIGHSCSAFDILQLRSQVVAGTNYFAKVHIG 240 M+ GG + + E + I VKPQ+E++ + F ++ +SQVVAG NY+ K+ G Sbjct: 1 MIPGGLTEAKPATIEIQEIANMVKPQLEEKTNETYEEFTAIEYKSQVVAGINYYIKIQTG 60 Query: 241 DGKHIHIRVYQPLPGQG-DLALHGLQ-EKLKEDVLEYF 348 D ++IHI+V++ LP Q L L G Q +K K+D L F Sbjct: 61 DNRYIHIKVFKSLPQQSHSLILTGYQVDKTKDDELAGF 98
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 54,019,141 Number of Sequences: 369166 Number of extensions: 1037086 Number of successful extensions: 2358 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2317 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2355 length of database: 68,354,980 effective HSP length: 102 effective length of database: 49,512,010 effective search space used: 3020232610 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)