Planaria EST Database

DrC_00924

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00924
         (1255 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|O62806|MMP13_RABIT  Collagenase 3 precursor (Matrix metal...   142   3e-33
sp|P22757|HE_PARLI  Hatching enzyme precursor (HE) (HEZ) (En...   141   3e-33
sp|P45452|MMP13_HUMAN  Collagenase 3 precursor (Matrix metal...   140   6e-33
sp|Q9Y5R2|MMP24_HUMAN  Matrix metalloproteinase-24 precursor...   136   1e-31
sp|Q9R0S2|MMP24_MOUSE  Matrix metalloproteinase-24 precursor...   135   2e-31
sp|Q99PW6|MMP24_RAT  Matrix metalloproteinase-24 precursor (...   135   2e-31
sp|P91953|HE_HEMPU  50 kDa hatching enzyme precursor (HE) (H...   135   2e-31
sp|P33435|MMP13_MOUSE  Collagenase 3 precursor (Matrix metal...   135   2e-31
sp|P23097|MMP13_RAT  Collagenase 3 precursor (Matrix metallo...   134   6e-31
sp|O77656|MMP13_BOVIN  Collagenase 3 precursor (Matrix metal...   134   7e-31

>sp|O62806|MMP13_RABIT Collagenase 3 precursor (Matrix metalloproteinase-13) (MMP-13)
          Length = 471

 Score =  142 bits (357), Expect = 3e-33
 Identities = 117/380 (30%), Positives = 177/380 (46%), Gaps = 21/380 (5%)
 Frame = +1

Query: 1    ILLSVLFIYSVQSFKSSEEKD--------AEKYLTDFYD--------YDESSGNFEDSIK 132
            +LLS    +S+    S+E+ D        AE YL  +Y            ++G+  D ++
Sbjct: 10   LLLSWTHCWSLPLLNSNEDDDLSEEDFQFAESYLRSYYHPLNPAGILKKNAAGSMVDRLR 69

Query: 133  ELQKMAGIEQDGELSDEVLSHMNKGRCGGKDREKKNKRYVASGAKWDRGVTYKYYLHLDW 312
            E+Q   G+E  G+L D  L+ M + RCG  D  + N        KW +  T   Y  +++
Sbjct: 70   EMQSFFGLEVTGKLDDNTLAIMKQPRCGVPDVGEYN--VFPRTLKWSQ--TNLTYRIVNY 125

Query: 313  MPRTMSEAEVRRAFKVALDYWVRVSNLGFSESRDKVGCKFSISFSGKDHLMYNVDNNFQS 492
             P  ++ +EV +AFK A   W  V+ L F+   +       ISF  K+H           
Sbjct: 126  TP-DLTHSEVEKAFKKAFKVWSDVTPLNFTRIHNGTA-DIMISFGTKEH----------- 172

Query: 493  QRDPSPLDNVPGGVLAHAYFPR---NGNLHCDNAETWTEGKDSGINLRIVAAHEMGHAIG 663
              D  P D  P G+LAHA+ P     G+ H D+ ETWT     G NL +VAAHE GH++G
Sbjct: 173  -GDFYPFDG-PSGLLAHAFPPGPNYGGDAHFDDDETWTSSS-KGYNLFLVAAHEFGHSLG 229

Query: 664  LHHSQDPSALMAPWYGGYISEAEYRLPNDDTLGAQSIYGARGKRALPSKKRELGKIQSRL 843
            L HS+DP ALM P Y  Y  ++ + LP+DD  G QS+YG   +   P   +   K     
Sbjct: 230  LDHSKDPGALMFPIY-TYTGKSHFMLPDDDVQGIQSLYGPGDEDPNPKHPKTPDK----- 283

Query: 844  CNVKSFEDVFTFSDGKVYVLADGGNLFRMNDDKVD-ETFEPVKINEALMN-VDSTFYDNV 1017
            C+     D  T   G+  +  D    +R++  +VD E F        L N +D+ +    
Sbjct: 284  CDPSLSLDAITSLRGETMIFKD-RFFWRLHPQQVDAELFLTKSFWPELPNRIDAAYEHPA 342

Query: 1018 KKRLIAFKGEKAFSVTGSDI 1077
            +  +  F+G+K ++  G DI
Sbjct: 343  RDLIFIFRGKKFWAPNGYDI 362

>sp|P22757|HE_PARLI Hatching enzyme precursor (HE) (HEZ) (Envelysin)
           (Sea-urchin-hatching proteinase) [Contains: Hatching
           enzyme 18 kDa form]
          Length = 587

 Score =  141 bits (356), Expect = 3e-33
 Identities = 90/232 (38%), Positives = 120/232 (51%), Gaps = 2/232 (0%)
 Frame = +1

Query: 94  YDESSGNFEDSIKELQKMAGIEQDGELSDEVLSHMNKGRCGGKDREKKNKRYVASGAKWD 273
           + E++ N+  +I + Q+  GI Q G L  +    ++  RCG  D       +V S   W 
Sbjct: 120 FGEANLNYTSAILDFQEHGGINQTGILDADTAELLSTPRCGVPDVLP----FVTSSITWS 175

Query: 274 RG--VTYKYYLHLDWMPRTMSEAEVRRAFKVALDYWVRVSNLGFSESRDKVGCKFSISFS 447
           R   VTY +      + +   + E+RRAF+V    W  VS L F E  D       I F 
Sbjct: 176 RNQPVTYSFGALTSDLNQNDVKDEIRRAFRV----WDDVSGLSFREVPDTTSVDIRIKFG 231

Query: 448 GKDHLMYNVDNNFQSQRDPSPLDNVPGGVLAHAYFPRNGNLHCDNAETWTEGKDSGINLR 627
             DH             D    D   GGVLAHA+ PRNG+ H D++ETWTEG  SG NL 
Sbjct: 232 SYDH------------GDGISFDG-RGGVLAHAFLPRNGDAHFDDSETWTEGTRSGTNLF 278

Query: 628 IVAAHEMGHAIGLHHSQDPSALMAPWYGGYISEAEYRLPNDDTLGAQSIYGA 783
            VAAHE GH++GL+HS   SALM P+Y GY+    +RL NDD  G +S+YG+
Sbjct: 279 QVAAHEFGHSLGLYHSTVRSALMYPYYQGYV--PNFRLDNDDIAGIRSLYGS 328

>sp|P45452|MMP13_HUMAN Collagenase 3 precursor (Matrix metalloproteinase-13) (MMP-13)
          Length = 471

 Score =  140 bits (354), Expect = 6e-33
 Identities = 113/352 (32%), Positives = 167/352 (47%), Gaps = 14/352 (3%)
 Frame = +1

Query: 64   AEKYLTDFYD--------YDESSGNFEDSIKELQKMAGIEQDGELSDEVLSHMNKGRCGG 219
            AE+YL  +Y          + ++ +  + ++E+Q   G+E  G+L D  L  M K RCG 
Sbjct: 39   AERYLRSYYHPTNLAGILKENAASSMTERLREMQSFFGLEVTGKLDDNTLDVMKKPRCGV 98

Query: 220  KDREKKNKRYVASGAKWDR-GVTYKYYLHLDWMPRTMSEAEVRRAFKVALDYWVRVSNLG 396
             D  + N        KW +  +TY+    +++ P  M+ +EV +AFK A   W  V+ L 
Sbjct: 99   PDVGEYN--VFPRTLKWSKMNLTYRI---VNYTP-DMTHSEVEKAFKKAFKVWSDVTPLN 152

Query: 397  FSESRDKVGCKFSISFSGKDHLMYNVDNNFQSQRDPSPLDNVPGGVLAHAYFPR---NGN 567
            F+   D +     ISF  K+H             D  P D  P G+LAHA+ P     G+
Sbjct: 153  FTRLHDGIA-DIMISFGIKEH------------GDFYPFDG-PSGLLAHAFPPGPNYGGD 198

Query: 568  LHCDNAETWTEGKDSGINLRIVAAHEMGHAIGLHHSQDPSALMAPWYGGYISEAEYRLPN 747
             H D+ ETWT     G NL +VAAHE GH++GL HS+DP ALM P Y  Y  ++ + LP+
Sbjct: 199  AHFDDDETWTSSS-KGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIY-TYTGKSHFMLPD 256

Query: 748  DDTLGAQSIYGARGKRALPSKKRELGKIQSRLCNVKSFEDVFTFSDGKVYVLADGGNLFR 927
            DD  G QS+YG   +   P   +   K     C+     D  T   G+  +  D    +R
Sbjct: 257  DDVQGIQSLYGPGDEDPNPKHPKTPDK-----CDPSLSLDAITSLRGETMIFKD-RFFWR 310

Query: 928  MNDDKVD-ETFEPVKINEALMNVDSTFYDNVKKRLI-AFKGEKAFSVTGSDI 1077
            ++  +VD E F        L N     Y++    LI  F+G K +++ G DI
Sbjct: 311  LHPQQVDAELFLTKSFWPELPNRIDAAYEHPSHDLIFIFRGRKFWALNGYDI 362

>sp|Q9Y5R2|MMP24_HUMAN Matrix metalloproteinase-24 precursor (MMP-24) (Membrane-type matrix
            metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix
            metalloproteinase) (MT5-MMP)
          Length = 645

 Score =  136 bits (342), Expect = 1e-31
 Identities = 114/367 (31%), Positives = 173/367 (47%), Gaps = 51/367 (13%)
 Frame = +1

Query: 103  SSGNFEDSIKELQKMAGIEQDGELSDEVLSHMNKGRCGGKD-----REKKNKRYVASGAK 267
            S+   + ++  +Q+  GI   G L    +  M K RCG  D     R ++NKRY  +G K
Sbjct: 103  SAKALQSAVSTMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDHPHLSRRRRNKRYALTGQK 162

Query: 268  W-DRGVTYKYYLHLDWMPRTMSEAEVRRAFKVALDYWVRVSNLGFSE------SRDKVGC 426
            W  + +TY  +   ++ P+ + E + R+A + A D W +V+ L F E        D+   
Sbjct: 163  WRQKHITYSIH---NYTPK-VGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIKSDRKEA 218

Query: 427  KFSISFSGKDHLMYNVDNNFQSQRDPSPLDNVPGGVLAHAYFPR---NGNLHCDNAETWT 597
               I F+   H             D SP D   GG LAHAYFP     G+ H D+ E WT
Sbjct: 219  DIMIFFASGFH------------GDSSPFDG-EGGFLAHAYFPGPGIGGDTHFDSDEPWT 265

Query: 598  EGKDS--GINLRIVAAHEMGHAIGLHHSQDPSALMAPWYGGYISEAEYRLPNDDTLGAQS 771
             G  +  G +L +VA HE+GHA+GL HS DPSA+MAP+Y  Y+    ++LP DD  G Q 
Sbjct: 266  LGNANHDGNDLFLVAVHELGHALGLEHSSDPSAIMAPFY-QYMETHNFKLPQDDLQGIQK 324

Query: 772  IYGARGK-----RALPS-----------KKRE---------LGKIQS------RLCNVKS 858
            IYG   +     R LP+           +K E         LG   S       +C+  +
Sbjct: 325  IYGPPAEPLEPTRPLPTLPVRRIHSPSERKHERQPRPPRPPLGDRPSTPGTKPNICD-GN 383

Query: 859  FEDVFTFSDGKVYVLADGGNLFRMNDDKVDETFEPVKINEALMNVDSTF---YDNVKKRL 1029
            F  V  F  G+++V  D    +R+ +++V E + P++I +    + +     Y+    R 
Sbjct: 384  FNTVALFR-GEMFVFKDRW-FWRLRNNRVQEGY-PMQIEQFWKGLPARIDAAYERADGRF 440

Query: 1030 IAFKGEK 1050
            + FKG+K
Sbjct: 441  VFFKGDK 447

>sp|Q9R0S2|MMP24_MOUSE Matrix metalloproteinase-24 precursor (MMP-24) (Membrane-type matrix
            metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix
            metalloproteinase) (MT5-MMP) (MMP-21)
          Length = 618

 Score =  135 bits (341), Expect = 2e-31
 Identities = 113/362 (31%), Positives = 171/362 (47%), Gaps = 51/362 (14%)
 Frame = +1

Query: 118  EDSIKELQKMAGIEQDGELSDEVLSHMNKGRCGGKD-----REKKNKRYVASGAKW-DRG 279
            + ++  +Q+  GI   G L    +  M K RCG  D     R ++NKRY  +G KW  + 
Sbjct: 81   QSAVSTMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDHPHLSRRRRNKRYALTGQKWRQKH 140

Query: 280  VTYKYYLHLDWMPRTMSEAEVRRAFKVALDYWVRVSNLGFSE------SRDKVGCKFSIS 441
            +TY  +   ++ P+ + E + R+A + A D W +V+ L F E        D+      I 
Sbjct: 141  ITYSIH---NYTPK-VGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIKSDRKEADIMIF 196

Query: 442  FSGKDHLMYNVDNNFQSQRDPSPLDNVPGGVLAHAYFPR---NGNLHCDNAETWTEGKDS 612
            F+   H             D SP D   GG LAHAYFP     G+ H D+ E WT G  +
Sbjct: 197  FASGFH------------GDSSPFDG-EGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNAN 243

Query: 613  --GINLRIVAAHEMGHAIGLHHSQDPSALMAPWYGGYISEAEYRLPNDDTLGAQSIYGAR 786
              G +L +VA HE+GHA+GL HS DPSA+MAP+Y  Y+    ++LP DD  G Q IYG  
Sbjct: 244  HDGNDLFLVAVHELGHALGLEHSNDPSAIMAPFY-QYMETHNFKLPQDDLQGIQKIYGPP 302

Query: 787  GK-----RALPS-----------KKRE---------LGKIQS------RLCNVKSFEDVF 873
             +     R LP+           +K E         LG   S       +C+  +F  V 
Sbjct: 303  AEPLEPTRPLPTLPVRRIHSPSERKHERHPRPPRPPLGDRPSTPGAKPNICD-GNFNTVA 361

Query: 874  TFSDGKVYVLADGGNLFRMNDDKVDETFEPVKINEALMNVDSTF---YDNVKKRLIAFKG 1044
             F  G+++V  D    +R+ +++V E + P++I +    + +     Y+    R + FKG
Sbjct: 362  LFR-GEMFVFKDRW-FWRLRNNRVQEGY-PMQIEQFWKGLPARIDAAYERADGRFVFFKG 418

Query: 1045 EK 1050
            +K
Sbjct: 419  DK 420

>sp|Q99PW6|MMP24_RAT Matrix metalloproteinase-24 precursor (MMP-24) (Membrane-type matrix
            metalloproteinase 5) (MT-MMP 5) (Membrane-type-5 matrix
            metalloproteinase) (MT5-MMP)
          Length = 618

 Score =  135 bits (341), Expect = 2e-31
 Identities = 113/362 (31%), Positives = 171/362 (47%), Gaps = 51/362 (14%)
 Frame = +1

Query: 118  EDSIKELQKMAGIEQDGELSDEVLSHMNKGRCGGKD-----REKKNKRYVASGAKW-DRG 279
            + ++  +Q+  GI   G L    +  M K RCG  D     R ++NKRY  +G KW  + 
Sbjct: 81   QSAVSTMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDHPHLSRRRRNKRYALTGQKWRQKH 140

Query: 280  VTYKYYLHLDWMPRTMSEAEVRRAFKVALDYWVRVSNLGFSE------SRDKVGCKFSIS 441
            +TY  +   ++ P+ + E + R+A + A D W +V+ L F E        D+      I 
Sbjct: 141  ITYSIH---NYTPK-VGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIKSDRKEADIMIF 196

Query: 442  FSGKDHLMYNVDNNFQSQRDPSPLDNVPGGVLAHAYFPR---NGNLHCDNAETWTEGKDS 612
            F+   H             D SP D   GG LAHAYFP     G+ H D+ E WT G  +
Sbjct: 197  FASGFH------------GDSSPFDG-EGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNAN 243

Query: 613  --GINLRIVAAHEMGHAIGLHHSQDPSALMAPWYGGYISEAEYRLPNDDTLGAQSIYGAR 786
              G +L +VA HE+GHA+GL HS DPSA+MAP+Y  Y+    ++LP DD  G Q IYG  
Sbjct: 244  HDGNDLFLVAVHELGHALGLEHSNDPSAIMAPFY-QYMETHNFKLPQDDLQGIQKIYGPP 302

Query: 787  GK-----RALPS-----------KKRE---------LGKIQS------RLCNVKSFEDVF 873
             +     R LP+           +K E         LG   S       +C+  +F  V 
Sbjct: 303  AEPLEPTRPLPTLPVRRIHSPSERKHERQPRPPRPPLGDRPSTPGAKPNICD-GNFNTVA 361

Query: 874  TFSDGKVYVLADGGNLFRMNDDKVDETFEPVKINEALMNVDSTF---YDNVKKRLIAFKG 1044
             F  G+++V  D    +R+ +++V E + P++I +    + +     Y+    R + FKG
Sbjct: 362  LFR-GEMFVFKDRW-FWRLRNNRVQEGY-PMQIEQFWKGLPARIDAAYERADGRFVFFKG 418

Query: 1045 EK 1050
            +K
Sbjct: 419  DK 420

>sp|P91953|HE_HEMPU 50 kDa hatching enzyme precursor (HE) (HEZ) (Envelysin)
           (Sea-urchin-hatching proteinase) [Contains: 38 kDa
           hatching enzyme; 32 kDa hatching enzyme non-specific; 15
           kDa peptide]
          Length = 591

 Score =  135 bits (341), Expect = 2e-31
 Identities = 89/231 (38%), Positives = 119/231 (51%), Gaps = 2/231 (0%)
 Frame = +1

Query: 94  YDESSGNFEDSIKELQKMAGIEQDGELSDEVLSHMNKGRCGGKDREKKNKRYVASGAKWD 273
           + E++ N+  +I E Q+  GI Q G L  E  + ++  RCG  D       YV  G  W 
Sbjct: 123 FGEANINYTSAILEYQQNGGINQTGILDAETAALLDTPRCGVPDILP----YVTGGIAWP 178

Query: 274 RGV--TYKYYLHLDWMPRTMSEAEVRRAFKVALDYWVRVSNLGFSESRDKVGCKFSISFS 447
           R V  TY +    + + +T  + E+RRAF+V    W  VS+L F E  D       I F 
Sbjct: 179 RNVAVTYSFGTLSNDLSQTAIKNELRRAFQV----WDDVSSLTFREVVDSSSVDIRIKFG 234

Query: 448 GKDHLMYNVDNNFQSQRDPSPLDNVPGGVLAHAYFPRNGNLHCDNAETWTEGKDSGINLR 627
             +H       +F  Q          GGVLAHA+ PRNG+ H D++E WT G +SG NL 
Sbjct: 235 SYEH---GDGISFDGQ----------GGVLAHAFLPRNGDAHFDDSERWTIGTNSGTNLF 281

Query: 628 IVAAHEMGHAIGLHHSQDPSALMAPWYGGYISEAEYRLPNDDTLGAQSIYG 780
            VAAHE GH++GL+HS   SALM P+Y GY     + L  DD  G  S+YG
Sbjct: 282 QVAAHEFGHSLGLYHSDVQSALMYPYYRGY--NPNFNLDRDDIAGITSLYG 330

>sp|P33435|MMP13_MOUSE Collagenase 3 precursor (Matrix metalloproteinase-13) (MMP-13)
          Length = 472

 Score =  135 bits (340), Expect = 2e-31
 Identities = 113/351 (32%), Positives = 163/351 (46%), Gaps = 13/351 (3%)
 Frame = +1

Query: 64   AEKYLTDFYDYDESSGNFE--------DSIKELQKMAGIEQDGELSDEVLSHMNKGRCGG 219
            AE YL  +Y     +G  +        D ++E+Q   G+E  G+L D  L  M K RCG 
Sbjct: 40   AEHYLKSYYHPATLAGILKKSTVTSTVDRLREMQSFFGLEVTGKLDDPTLDIMRKPRCGV 99

Query: 220  KDREKKNKRYVASGAKWDRGVTYKYYLHLDWMPRTMSEAEVRRAFKVALDYWVRVSNLGF 399
             D  + N        KW +  T   Y  +++ P  MS +EV +AF+ A   W  V+ L F
Sbjct: 100  PDVGEYN--VFPRTLKWSQ--TNLTYRIVNYTP-DMSHSEVEKAFRKAFKVWSDVTPLNF 154

Query: 400  SESRDKVGCKFSISFSGKDHLMYNVDNNFQSQRDPSPLDNVPGGVLAHAYFPR---NGNL 570
            +   D       ISF  K+H             D  P D  P G+LAHA+ P     G+ 
Sbjct: 155  TRIYDGTA-DIMISFGTKEH------------GDFYPFDG-PSGLLAHAFPPGPNYGGDA 200

Query: 571  HCDNAETWTEGKDSGINLRIVAAHEMGHAIGLHHSQDPSALMAPWYGGYISEAEYRLPND 750
            H D+ ETWT     G NL IVAAHE+GH++GL HS+DP ALM P Y  Y  ++ + LP+D
Sbjct: 201  HFDDDETWTSSS-KGYNLFIVAAHELGHSLGLDHSKDPGALMFPIY-TYTGKSHFMLPDD 258

Query: 751  DTLGAQSIYGARGKRALPSKKRELGKIQSRLCNVKSFEDVFTFSDGKVYVLADGGNLFRM 930
            D  G Q +YG   +   P   +   K     C+     D  T   G+  +  D    +R+
Sbjct: 259  DVQGIQFLYGPGDEDPNPKHPKTPEK-----CDPALSLDAITSLRGETMIFKD-RFFWRL 312

Query: 931  NDDKVD-ETFEPVKINEALMN-VDSTFYDNVKKRLIAFKGEKAFSVTGSDI 1077
            +  +V+ E F        L N VD+ +    +  +  F+G K +++ G DI
Sbjct: 313  HPQQVEAELFLTKSFWPELPNHVDAAYEHPSRDLMFIFRGRKFWALNGYDI 363

>sp|P23097|MMP13_RAT Collagenase 3 precursor (Matrix metalloproteinase-13) (MMP-13)
            (UMRCASE)
          Length = 466

 Score =  134 bits (337), Expect = 6e-31
 Identities = 112/351 (31%), Positives = 163/351 (46%), Gaps = 13/351 (3%)
 Frame = +1

Query: 64   AEKYLTDFYDYDESSGNFE--------DSIKELQKMAGIEQDGELSDEVLSHMNKGRCGG 219
            AE YL  +Y     +G  +        D ++E+Q   G++  G+L D  L  M K RCG 
Sbjct: 34   AEHYLKSYYHPVTLAGILKKSTVTSTVDRLREMQSFFGLDVTGKLDDPTLDIMRKPRCGV 93

Query: 220  KDREKKNKRYVASGAKWDRGVTYKYYLHLDWMPRTMSEAEVRRAFKVALDYWVRVSNLGF 399
             D    N        KW +  T   Y  +++ P  +S +EV +AF+ A   W  V+ L F
Sbjct: 94   PDVGVYN--VFPRTLKWSQ--TNLTYRIVNYTP-DISHSEVEKAFRKAFKVWSDVTPLNF 148

Query: 400  SESRDKVGCKFSISFSGKDHLMYNVDNNFQSQRDPSPLDNVPGGVLAHAYFPR---NGNL 570
            +   D       ISF  K+H             D  P D  P G+LAHA+ P     G+ 
Sbjct: 149  TRIHDGTA-DIMISFGTKEH------------GDFYPFDG-PSGLLAHAFPPGPNLGGDA 194

Query: 571  HCDNAETWTEGKDSGINLRIVAAHEMGHAIGLHHSQDPSALMAPWYGGYISEAEYRLPND 750
            H D+ ETWT     G NL IVAAHE+GH++GL HS+DP ALM P Y  Y  ++ + LP+D
Sbjct: 195  HFDDDETWTSSS-KGYNLFIVAAHELGHSLGLDHSKDPGALMFPIY-TYTGKSHFMLPDD 252

Query: 751  DTLGAQSIYGARGKRALPSKKRELGKIQSRLCNVKSFEDVFTFSDGKVYVLADGGNLFRM 930
            D  G QS+YG   +   P   +   K     C+     D  T   G+  +  D    +R+
Sbjct: 253  DVQGIQSLYGPGDEDPNPKHPKTPEK-----CDPALSLDAITSLRGETMIFKD-RFFWRL 306

Query: 931  NDDKVD-ETFEPVKINEALMN-VDSTFYDNVKKRLIAFKGEKAFSVTGSDI 1077
            +  +V+ E F        L N VD+ +    +  +  F+G K +++ G DI
Sbjct: 307  HPQQVEPELFLTKSFWPELPNHVDAAYEHPSRDLMFIFRGRKFWALNGYDI 357

>sp|O77656|MMP13_BOVIN Collagenase 3 precursor (Matrix metalloproteinase-13) (MMP-13)
          Length = 471

 Score =  134 bits (336), Expect = 7e-31
 Identities = 114/368 (30%), Positives = 168/368 (45%), Gaps = 17/368 (4%)
 Frame = +1

Query: 64   AEKYLTDFYDYDESSGNFE--------DSIKELQKMAGIEQDGELSDEVLSHMNKGRCGG 219
            AE YL  +Y     +G  +        D ++E+Q   G+E  G L D  L  M K RCG 
Sbjct: 39   AESYLKSYYYPQNPAGILKKTAASSVIDRLREMQSFFGLEVTGRLDDNTLDIMKKPRCGV 98

Query: 220  KDREKKNKRYVASGAKWDR-GVTYKYYLHLDWMPRTMSEAEVRRAFKVALDYWVRVSNLG 396
             D  + N        KW +  +TY+    +++ P  ++ +EV +AF+ A   W  V+ L 
Sbjct: 99   PDVGEYN--VFPRTLKWSKMNLTYRI---VNYTP-DLTHSEVEKAFRKAFKVWSDVTPLN 152

Query: 397  FSESRDKVGCKFSISFSGKDHLMYNVDNNFQSQRDPSPLDNVPGGVLAHAYFPR---NGN 567
            F+   +       ISF  K+H             D  P D  P G+LAHA+ P     G+
Sbjct: 153  FTRIHNGTA-DIMISFGTKEH------------GDFYPFDG-PSGLLAHAFPPGPNYGGD 198

Query: 568  LHCDNAETWTEGKDSGINLRIVAAHEMGHAIGLHHSQDPSALMAPWYGGYISEAEYRLPN 747
             H D+ ETWT     G NL +VAAHE GH++GL HS+DP ALM P Y  Y  ++ + LP+
Sbjct: 199  AHFDDDETWTSSS-KGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIY-TYTGKSHFMLPD 256

Query: 748  DDTLGAQSIYGARGKRALPSKKRELGKIQSRLCNVKSFEDVFTFSDGKVYVLADGGNLFR 927
            DD  G QS+YG   +       +   K     C+     D  T   G+  +  D    +R
Sbjct: 257  DDVQGIQSLYGPGDEDPYSKHPKTPDK-----CDPSLSLDAITSLRGETLIFKD-RFFWR 310

Query: 928  MNDDKVD-ETFEPVKINEALMNVDSTFYDNVKKRLI-AFKGEKAFSVTGSDIEN---LKV 1092
            ++  +V+ E F        L N     Y++    LI  F+G K ++++G DI      K+
Sbjct: 311  LHPQQVEAELFLTKSFGPELPNRIDAAYEHPSHDLIFIFRGRKFWALSGYDILEDYPKKI 370

Query: 1093 EELVISDH 1116
             EL    H
Sbjct: 371  SELGFPKH 378

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.317    0.135    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 148,694,957
Number of Sequences: 369166
Number of extensions: 3248828
Number of successful extensions: 10149
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 9396
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9930
length of database: 68,354,980
effective HSP length: 113
effective length of database: 47,479,925
effective search space used: 14433897200
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)

Cluster detail

DrC_00924

  1. Dr_sW_015_H04
  2. Dr_sW_023_E24
  3. Dr_sW_018_P19
  4. Dr_sW_011_J20
  5. Dr_sW_013_F19
  6. Dr_sW_009_E08