Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00920 (994 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q01241|NF70_LOLPE 70 kDa neurofilament protein (NF70) 170 7e-42 sp|Q01240|NF60_LOLPE 60 kDa neurofilament protein (NF60) 170 7e-42 sp|P90901|IFA1_CAEEL Intermediate filament protein ifa-1 (I... 138 3e-32 sp|O02365|IFA2_CAEEL Intermediate filament protein ifa-2 (I... 120 5e-27 sp|P90900|IFA4_CAEEL Intermediate filament protein ifa-4 (I... 119 1e-26 sp|P23730|IFEA_ASCSU Intermediate filament protein A (IF-A) 114 3e-25 sp|Q21065|IFA3_CAEEL Intermediate filament protein ifa-3 (I... 113 1e-24 sp|P22488|IFEA_HELAS Non-neuronal cytoplasmic intermediate ... 110 5e-24 sp|P16275|IFEB_HELPO Non-neuronal cytoplasmic intermediate ... 108 2e-23 sp|P23731|IFEB_ASCSU Intermediate filament protein B (IF-B) 108 2e-23
>sp|Q01241|NF70_LOLPE 70 kDa neurofilament protein (NF70) Length = 615 Score = 170 bits (430), Expect = 7e-42 Identities = 84/219 (38%), Positives = 137/219 (62%) Frame = +3 Query: 336 TGVNSIKKGREQEKKNLQGLNERFASYIEKARYLEEQNKQLVGEIETLKGGNIDDTSKIK 515 TGVN +K RE+EK++++ LNERFA+YIEK R+LE QNK+L GE+E LK +TS IK Sbjct: 84 TGVNHVKANREREKQDMRDLNERFANYIEKVRFLEAQNKKLAGELEELKSKWGKETSAIK 143 Query: 516 EIYEVEINQLRSLLNESEKSRAPLEIQINSLEYEIDEMQKRLMLLEDINSQYRGTIEKQR 695 E+YE E+ + R L++ + K + L++++ L +++ QK L + + I +Q Sbjct: 144 EMYETELEEARKLIDATNKEKITLDVRVTELIDQLERQQKDLEESRTYHQIDQEQIARQN 203 Query: 696 RELETFEGDLVELRRFKGTREVDSDKEKQETSVLRDEIKKLRQDYEREALAHITLEHDLQ 875 ++L EG++ LRR + E + ++ + + DE++K+R D E + H+ E+ Q Sbjct: 204 QQLADLEGEISMLRRSIESLEKEKMRQSNILAKMNDEMEKMRMDLNNETINHLDAENRRQ 263 Query: 876 TLRETIEFEKQIHTTEMKELTTVAYRDPSKENLVYWQSE 992 TL E +EF+K +H E+KEL +AYRD + EN +W++E Sbjct: 264 TLEEELEFQKDVHAQELKELAALAYRDTTAENREFWRNE 302
>sp|Q01240|NF60_LOLPE 60 kDa neurofilament protein (NF60) Length = 511 Score = 170 bits (430), Expect = 7e-42 Identities = 84/219 (38%), Positives = 137/219 (62%) Frame = +3 Query: 336 TGVNSIKKGREQEKKNLQGLNERFASYIEKARYLEEQNKQLVGEIETLKGGNIDDTSKIK 515 TGVN +K RE+EK++++ LNERFA+YIEK R+LE QNK+L GE+E LK +TS IK Sbjct: 84 TGVNHVKANREREKQDMRDLNERFANYIEKVRFLEAQNKKLAGELEELKSKWGKETSAIK 143 Query: 516 EIYEVEINQLRSLLNESEKSRAPLEIQINSLEYEIDEMQKRLMLLEDINSQYRGTIEKQR 695 E+YE E+ + R L++ + K + L++++ L +++ QK L + + I +Q Sbjct: 144 EMYETELEEARKLIDATNKEKITLDVRVTELIDQLERQQKDLEESRTYHQIDQEQIARQN 203 Query: 696 RELETFEGDLVELRRFKGTREVDSDKEKQETSVLRDEIKKLRQDYEREALAHITLEHDLQ 875 ++L EG++ LRR + E + ++ + + DE++K+R D E + H+ E+ Q Sbjct: 204 QQLADLEGEISMLRRSIESLEKEKMRQSNILAKMNDEMEKMRMDLNNETINHLDAENRRQ 263 Query: 876 TLRETIEFEKQIHTTEMKELTTVAYRDPSKENLVYWQSE 992 TL E +EF+K +H E+KEL +AYRD + EN +W++E Sbjct: 264 TLEEELEFQKDVHAQELKELAALAYRDTTAENREFWRNE 302
>sp|P90901|IFA1_CAEEL Intermediate filament protein ifa-1 (Intermediate filament protein A1) (IF-A1) (Cel IF A1) Length = 575 Score = 138 bits (347), Expect = 3e-32 Identities = 75/220 (34%), Positives = 128/220 (58%) Frame = +3 Query: 333 QTGVNSIKKGREQEKKNLQGLNERFASYIEKARYLEEQNKQLVGEIETLKGGNIDDTSKI 512 Q ++I+ RE+EKK + LN+R ASYIEK R+LE QN++L +++ L+ DT I Sbjct: 56 QNAASTIRDSREREKKEMSDLNDRLASYIEKVRFLEAQNRKLAADLDALRSKWGKDTHNI 115 Query: 513 KEIYEVEINQLRSLLNESEKSRAPLEIQINSLEYEIDEMQKRLMLLEDINSQYRGTIEKQ 692 + +YE E+ + L++E+ K R +E Q+ ++ E+ EM+++L Q R I+ Sbjct: 116 RNMYEGELVDAQKLIDETNKQRKDMEGQLKKMQDELAEMRRKLEDATKGREQDRAKIDAL 175 Query: 693 RRELETFEGDLVELRRFKGTREVDSDKEKQETSVLRDEIKKLRQDYEREALAHITLEHDL 872 L E ++ L+R E + + KQE L E+++ R D ++E L I ++ + Sbjct: 176 LVTLSNLEAEISLLKRRIAQLEDEVKRIKQENQRLLSELQRARTDLDQETLNRIDYQNQV 235 Query: 873 QTLRETIEFEKQIHTTEMKELTTVAYRDPSKENLVYWQSE 992 QTL E I+F +++H E+KEL T+A RD + EN ++++E Sbjct: 236 QTLLEEIDFLRRVHDNEIKELQTLASRDTTPENREFFKNE 275
>sp|O02365|IFA2_CAEEL Intermediate filament protein ifa-2 (Intermediate filament protein A2) (IF-A2) (Cel IF A2) Length = 581 Score = 120 bits (302), Expect = 5e-27 Identities = 68/220 (30%), Positives = 126/220 (57%) Frame = +3 Query: 333 QTGVNSIKKGREQEKKNLQGLNERFASYIEKARYLEEQNKQLVGEIETLKGGNIDDTSKI 512 Q ++I+ RE+EKK + LN+R ASYIEK R+L+ QN++L +++ L+G T + Sbjct: 58 QNAASTIRDNREREKKEIMELNDRLASYIEKVRFLDAQNRKLDADLKMLQGRFGKSTGSV 117 Query: 513 KEIYEVEINQLRSLLNESEKSRAPLEIQINSLEYEIDEMQKRLMLLEDINSQYRGTIEKQ 692 K +YE+EI +++ ++ K E +I L+ ++DE++K+ + ++ R I+ Sbjct: 118 KVMYEMEITTATNVVKQTGKDHGETEKEIRKLQDQLDELRKKFEEAQRGRAEDRLKIDDL 177 Query: 693 RRELETFEGDLVELRRFKGTREVDSDKEKQETSVLRDEIKKLRQDYEREALAHITLEHDL 872 L E ++ L+R E + + K+E L E++++R + ++E L I ++ + Sbjct: 178 LVTLSNLEAEINLLKRRIALLEEEVARLKKENFRLTSELQRVRIELDQETLLRIDNQNKV 237 Query: 873 QTLRETIEFEKQIHTTEMKELTTVAYRDPSKENLVYWQSE 992 +T+ E I+F K+ TE+KEL A RD + EN Y+++E Sbjct: 238 KTILEEIDFMKRGFETELKELQAQAARDTTSENREYFKNE 277
Score = 41.2 bits (95), Expect = 0.005 Identities = 37/190 (19%), Positives = 88/190 (46%), Gaps = 10/190 (5%) Frame = +3 Query: 393 LNERFASYIEKARYLEEQNKQLVGEIETLKGG-------NIDDTSKIKEIYEVEINQLRS 551 L R A E+ L+++N +L E++ ++ ID+ +K+K I E R Sbjct: 191 LKRRIALLEEEVARLKKENFRLTSELQRVRIELDQETLLRIDNQNKVKTILEEIDFMKRG 250 Query: 552 LLNESEK--SRAPLEIQINSLEYEIDEMQKRLMLLEDINSQYRGTIEKQRRELET-FEGD 722 E ++ ++A + + EY +E+ + DI ++Y + R ++E+ ++ Sbjct: 251 FETELKELQAQAARDTTSENREYFKNELANAM---RDIRAEYDQIMNGNRNDMESWYQLR 307 Query: 723 LVELRRFKGTREVDSDKEKQETSVLRDEIKKLRQDYEREALAHITLEHDLQTLRETIEFE 902 + E+ + +++ +K+E LR++ +LRQ ++ LE ++ L +E + Sbjct: 308 VQEINTQSNRQNAENNYQKEEVKRLRNQTSELRQKLSDLESRNLLLEKQIEDLNYQLEDD 367 Query: 903 KQIHTTEMKE 932 ++ + + + Sbjct: 368 QRSYEAALND 377
>sp|P90900|IFA4_CAEEL Intermediate filament protein ifa-4 (Intermediate filament protein A4) (IF-A4) (Cel IF A4) Length = 575 Score = 119 bits (299), Expect = 1e-26 Identities = 69/216 (31%), Positives = 119/216 (55%) Frame = +3 Query: 345 NSIKKGREQEKKNLQGLNERFASYIEKARYLEEQNKQLVGEIETLKGGNIDDTSKIKEIY 524 ++I++ R +EKK + LN+R ASYIEK R+LE QN+++ ++ L+G D++ +K +Y Sbjct: 61 SAIRESRTREKKEMSELNDRLASYIEKVRFLEAQNRKMEKDLNLLRGKWGHDSTSVKVMY 120 Query: 525 EVEINQLRSLLNESEKSRAPLEIQINSLEYEIDEMQKRLMLLEDINSQYRGTIEKQRREL 704 E E+ + L+ +S+K RA LE QI L E++ + +L E R ++ L Sbjct: 121 ETELRSAKDLIADSDKERAQLEDQIKKLVEELNNYRNKLHEAERGADVTRKELDNVLGRL 180 Query: 705 ETFEGDLVELRRFKGTREVDSDKEKQETSVLRDEIKKLRQDYEREALAHITLEHDLQTLR 884 E ++ L+R E K+E + D + R E+E L I ++ +QTL Sbjct: 181 GALEAEIELLKRRISLMEESIGHLKRENHRMIDSLHHARNAVEQETLNRIDYQNQVQTLL 240 Query: 885 ETIEFEKQIHTTEMKELTTVAYRDPSKENLVYWQSE 992 E +F ++IH +E+ +L +A RD + EN Y+++E Sbjct: 241 EECDFIRRIHDSEIHDLLAMASRDTTVENREYFKNE 276
>sp|P23730|IFEA_ASCSU Intermediate filament protein A (IF-A) Length = 497 Score = 114 bits (286), Expect = 3e-25 Identities = 65/203 (32%), Positives = 114/203 (56%) Frame = +3 Query: 384 LQGLNERFASYIEKARYLEEQNKQLVGEIETLKGGNIDDTSKIKEIYEVEINQLRSLLNE 563 + LN+R ASYIEK R+LE QN++L +++ L+G DT ++ +YE E+ + R L+N+ Sbjct: 1 MSDLNDRLASYIEKVRFLEAQNRKLAADLDLLRGRWGKDTLSVRAMYEGELQEARKLVND 60 Query: 564 SEKSRAPLEIQINSLEYEIDEMQKRLMLLEDINSQYRGTIEKQRRELETFEGDLVELRRF 743 + + R LE +I L E+ E +++ + R I++ +L E ++ LRR Sbjct: 61 TNRQREELEKEIRKLLDELSEYRRKYEDALRGHQIDRDRIDELLNQLSGLEAEINLLRRR 120 Query: 744 KGTREVDSDKEKQETSVLRDEIKKLRQDYEREALAHITLEHDLQTLRETIEFEKQIHTTE 923 + + K+E +E+ K R D ++E L I ++ +QTL E I+F +++H E Sbjct: 121 IANIIEEIARIKKENLQFANELTKARSDLDQETLNRIDFQNQVQTLLEEIDFMRRVHDQE 180 Query: 924 MKELTTVAYRDPSKENLVYWQSE 992 + EL +A RD + EN Y+++E Sbjct: 181 IAELQAMASRDTTPENREYFKNE 203
>sp|Q21065|IFA3_CAEEL Intermediate filament protein ifa-3 (Intermediate filament protein A3) (IF-A3) (Cel IF A3) Length = 581 Score = 113 bits (282), Expect = 1e-24 Identities = 65/220 (29%), Positives = 122/220 (55%) Frame = +3 Query: 333 QTGVNSIKKGREQEKKNLQGLNERFASYIEKARYLEEQNKQLVGEIETLKGGNIDDTSKI 512 Q ++I+ RE+EKK + LN+R ASYI K R+L QN++L ++ L+ T + Sbjct: 58 QGAASTIRDDREREKKEITELNDRLASYIGKVRFLAAQNRKLEADLNVLQSRFGKSTGSV 117 Query: 513 KEIYEVEINQLRSLLNESEKSRAPLEIQINSLEYEIDEMQKRLMLLEDINSQYRGTIEKQ 692 K +YE+EI +++ E+ K E +I ++ ++DE++K+ + ++ R I++ Sbjct: 118 KIMYEMEITTATNVVKETGKDHEEAEKEIGKIKDQLDELRKKFEEAQKGRAEDRLKIDEL 177 Query: 693 RRELETFEGDLVELRRFKGTREVDSDKEKQETSVLRDEIKKLRQDYEREALAHITLEHDL 872 L E ++ L+R E + + K+E L E++++R + ++E L I ++ + Sbjct: 178 LVTLSNLEAEINLLKRRIALLEEEVARLKKENFRLTSELQRVRSELDQETLLRIDNQNKV 237 Query: 873 QTLRETIEFEKQIHTTEMKELTTVAYRDPSKENLVYWQSE 992 T+ E I+F K+ TE+K+L A RD + EN Y+++E Sbjct: 238 TTILEEIDFMKRGFETELKDLQAQAARDTTSENREYFKNE 277
>sp|P22488|IFEA_HELAS Non-neuronal cytoplasmic intermediate filament protein (IF) Length = 576 Score = 110 bits (276), Expect = 5e-24 Identities = 64/219 (29%), Positives = 118/219 (53%) Frame = +3 Query: 336 TGVNSIKKGREQEKKNLQGLNERFASYIEKARYLEEQNKQLVGEIETLKGGNIDDTSKIK 515 +G+ + RE+EK+ +Q LNER ASYIEK +L+ Q K+L E E L+ + I+ Sbjct: 61 SGITDFRGTREKEKREMQNLNERLASYIEKVHFLDAQVKKLEAENEALRNRKSESLQPIR 120 Query: 516 EIYEVEINQLRSLLNESEKSRAPLEIQINSLEYEIDEMQKRLMLLEDINSQYRGTIEKQR 695 + YE E+ Q R +++E ++ E ++ L+ EI +++ ++ E+ + YR IE Sbjct: 121 DAYENELAQARKVIDELSSTKGVSEAKVAGLQDEIASLRELIVTYENQSKDYRKKIESLG 180 Query: 696 RELETFEGDLVELRRFKGTREVDSDKEKQETSVLRDEIKKLRQDYEREALAHITLEHDLQ 875 ++ +EG+L LR G+ E ++ K ++ ++++ ++LR D + E AHI + Q Sbjct: 181 NQIGEYEGELHTLRIRCGSLEDENAKVRELLDKIQEQNRRLRADLDTETAAHIEADCLAQ 240 Query: 876 TLRETIEFEKQIHTTEMKELTTVAYRDPSKENLVYWQSE 992 T E EF K + +++ L + + +W+SE Sbjct: 241 TKTEEAEFYKDL-LDQLELLKPEPIQIKGMDYAEFWKSE 278
>sp|P16275|IFEB_HELPO Non-neuronal cytoplasmic intermediate filament protein B (IFB) Length = 450 Score = 108 bits (271), Expect = 2e-23 Identities = 64/219 (29%), Positives = 116/219 (52%) Frame = +3 Query: 336 TGVNSIKKGREQEKKNLQGLNERFASYIEKARYLEEQNKQLVGEIETLKGGNIDDTSKIK 515 +G+ + RE+EK+ +Q LNER A YIEK +L+ Q K+L E E L+ + I+ Sbjct: 59 SGITDFRGTREKEKREMQNLNERLAGYIEKVHFLDAQVKKLEAENEALRNRKSESLQPIR 118 Query: 516 EIYEVEINQLRSLLNESEKSRAPLEIQINSLEYEIDEMQKRLMLLEDINSQYRGTIEKQR 695 + YE E+ Q R +++E ++ E ++ L+ EI +++ + E+ + YR IE Sbjct: 119 DAYENELAQARKVIDELSSTKGVSEAKVAGLQDEIASLRELIGTYENQSKDYRKKIESLG 178 Query: 696 RELETFEGDLVELRRFKGTREVDSDKEKQETSVLRDEIKKLRQDYEREALAHITLEHDLQ 875 ++ +EG+L LR G+ E ++ K ++ ++D+ ++LR D + E AHI + Q Sbjct: 179 NQIGEYEGELHTLRIRCGSLEDENAKVRELLDKIQDQNRRLRADLDTETSAHIEADCLAQ 238 Query: 876 TLRETIEFEKQIHTTEMKELTTVAYRDPSKENLVYWQSE 992 T E EF K + +++ L + + +W+SE Sbjct: 239 TKTEECEFYKDL-LDQLELLKPEPMQIKGMDYAEFWKSE 276
>sp|P23731|IFEB_ASCSU Intermediate filament protein B (IF-B) Length = 589 Score = 108 bits (270), Expect = 2e-23 Identities = 64/222 (28%), Positives = 121/222 (54%), Gaps = 4/222 (1%) Frame = +3 Query: 309 IRGDSVALQTGV-NSIKKGREQEKKNLQGLNERFASYIEKARYLEEQNKQLVGEIETLKG 485 I G S AL S + ++EKK +QGLN+R +YI++ + LEEQN++LV +++ L+G Sbjct: 59 IGGISPALSANAAKSFLEATDKEKKEMQGLNDRLGNYIDRVKKLEEQNRKLVADLDELRG 118 Query: 486 GNIDDTSKIKEIYEVEINQLRSLLNESEKSRAPLEIQINSLEYEIDEMQKRLMLLEDINS 665 DTS+IK Y + R +++ + +A +++++ L ++ E++ R ED+ Sbjct: 119 RWGKDTSEIKIQYSDSLRDARKEIDDGARRKAEIDVKVARLRDDLAELRNR---YEDVQH 175 Query: 666 QYRGTIEKQRRELETFEGDLVELRRFKGTREVDSDKEKQ---ETSVLRDEIKKLRQDYER 836 + EK + E EL + +++EK+ + + + +E++K R D + Sbjct: 176 RRESDREKINQWQHAIEDAQSELEMLRARWRQLTEEEKRLNGDNARIWEELQKARNDLDE 235 Query: 837 EALAHITLEHDLQTLRETIEFEKQIHTTEMKELTTVAYRDPS 962 E L I ++ +QTL E +EF +++H E+KEL + + P+ Sbjct: 236 ETLGRIDFQNQVQTLMEELEFLRRVHEQEVKELQALLAQAPA 277
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 80,285,561 Number of Sequences: 369166 Number of extensions: 1314040 Number of successful extensions: 6998 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5800 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6718 length of database: 68,354,980 effective HSP length: 111 effective length of database: 47,849,395 effective search space used: 10479017505 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)