Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00874 (869 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q24537|HMG2_DROME High mobility group protein DSP1 (Dors... 125 1e-28 sp|P10103|HMG1_BOVIN High mobility group protein 1 (HMG-1) ... 125 2e-28 sp|P09429|HMG1_HUMAN High mobility group protein 1 (HMG-1) ... 125 2e-28 sp|P63159|HMG1_RAT High mobility group protein 1 (HMG-1) (H... 125 2e-28 sp|P12682|HMG1_PIG High mobility group protein 1 (HMG-1) (H... 125 2e-28 sp|P52925|HMG2_RAT High mobility group protein 2 (HMG-2) 124 4e-28 sp|P26583|HMG2_HUMAN High mobility group protein 2 (HMG-2) 123 6e-28 sp|P30681|HMG2_MOUSE High mobility group protein 2 (HMG-2) 123 8e-28 sp|P17741|HMG2_PIG High mobility group protein 2 (HMG-2) 123 8e-28 sp|P26584|HMG2_CHICK High mobility group protein 2 (HMG-2) 122 1e-27
>sp|Q24537|HMG2_DROME High mobility group protein DSP1 (Dorsal switch protein 1) Length = 393 Score = 125 bits (315), Expect = 1e-28 Identities = 63/163 (38%), Positives = 92/163 (56%), Gaps = 13/163 (7%) Frame = +1 Query: 85 MAAYTYFVKLIRDEHRKKHPEEQFDFTEFSAKCAEKWKSMKPEERKRFEELASEEND--- 255 M AY YFV+ R+EH+KKHP+E F EFS KCAE+WK+M +E+KRF E+A ++ Sbjct: 183 MTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYE 242 Query: 256 --------XXXXXXXXXXXXXXXXXXGQPKRAWSAFFYFCDERRPKVRKEHPDWRVAEVA 411 PKR+ SAFF+FC++ R KV+ +P++ V ++A Sbjct: 243 AEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIA 302 Query: 412 RELGRLWEACSD--RDRYEKMATLDKERYEKEMEQFRAGNFVA 534 +ELGR W + +YE MA DK RYE+EM +++ +A Sbjct: 303 KELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYKTSGKIA 345
Score = 48.9 bits (115), Expect = 2e-05 Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 4/71 (5%) Frame = +1 Query: 313 QPKRAWSAFFYFCDERRPKVRKEHPDWRV--AEVARELGRLWEACSDRD--RYEKMATLD 480 +P+ +A+ YF R + +K+HPD V AE +R+ W+ D++ R+ +MA D Sbjct: 178 KPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKD 237 Query: 481 KERYEKEMEQF 513 K+RYE EM+ + Sbjct: 238 KQRYEAEMQNY 248
>sp|P10103|HMG1_BOVIN High mobility group protein 1 (HMG-1) (High mobility group protein B1) Length = 215 Score = 125 bits (314), Expect = 2e-28 Identities = 62/164 (37%), Positives = 93/164 (56%), Gaps = 7/164 (4%) Frame = +1 Query: 49 MDSSTGKSNKLTMAAYTYFVKLIRDEHRKKHPEEQFDFTEFSAKCAEKWKSMKPEERKRF 228 M K + M++Y +FV+ R+EH+KKHP+ +F+EFS KC+E+WK+M +E+ +F Sbjct: 1 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF 60 Query: 229 EELASE-----ENDXXXXXXXXXXXXXXXXXXGQPKRAWSAFFYFCDERRPKVRKEHPDW 393 E++A E + PKR SAFF FC E RPK++ EHP Sbjct: 61 EDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGL 120 Query: 394 RVAEVARELGRLWE--ACSDRDRYEKMATLDKERYEKEMEQFRA 519 + +VA++LG +W A D+ YEK A KE+YEK++ +RA Sbjct: 121 SIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRA 164
>sp|P09429|HMG1_HUMAN High mobility group protein 1 (HMG-1) (High mobility group protein B1) sp|Q6YKA4|HMG1_CANFA High mobility group protein 1 (HMG-1) (High mobility group protein B1) Length = 215 Score = 125 bits (314), Expect = 2e-28 Identities = 62/164 (37%), Positives = 93/164 (56%), Gaps = 7/164 (4%) Frame = +1 Query: 49 MDSSTGKSNKLTMAAYTYFVKLIRDEHRKKHPEEQFDFTEFSAKCAEKWKSMKPEERKRF 228 M K + M++Y +FV+ R+EH+KKHP+ +F+EFS KC+E+WK+M +E+ +F Sbjct: 1 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF 60 Query: 229 EELASE-----ENDXXXXXXXXXXXXXXXXXXGQPKRAWSAFFYFCDERRPKVRKEHPDW 393 E++A E + PKR SAFF FC E RPK++ EHP Sbjct: 61 EDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGL 120 Query: 394 RVAEVARELGRLWE--ACSDRDRYEKMATLDKERYEKEMEQFRA 519 + +VA++LG +W A D+ YEK A KE+YEK++ +RA Sbjct: 121 SIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRA 164
>sp|P63159|HMG1_RAT High mobility group protein 1 (HMG-1) (High mobility group protein B1) (Amphoterin) (Heparin-binding protein p30) sp|P63158|HMG1_MOUSE High mobility group protein 1 (HMG-1) (High mobility group protein B1) Length = 215 Score = 125 bits (314), Expect = 2e-28 Identities = 62/164 (37%), Positives = 93/164 (56%), Gaps = 7/164 (4%) Frame = +1 Query: 49 MDSSTGKSNKLTMAAYTYFVKLIRDEHRKKHPEEQFDFTEFSAKCAEKWKSMKPEERKRF 228 M K + M++Y +FV+ R+EH+KKHP+ +F+EFS KC+E+WK+M +E+ +F Sbjct: 1 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF 60 Query: 229 EELASE-----ENDXXXXXXXXXXXXXXXXXXGQPKRAWSAFFYFCDERRPKVRKEHPDW 393 E++A E + PKR SAFF FC E RPK++ EHP Sbjct: 61 EDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGL 120 Query: 394 RVAEVARELGRLWE--ACSDRDRYEKMATLDKERYEKEMEQFRA 519 + +VA++LG +W A D+ YEK A KE+YEK++ +RA Sbjct: 121 SIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRA 164
>sp|P12682|HMG1_PIG High mobility group protein 1 (HMG-1) (High mobility group protein B1) Length = 215 Score = 125 bits (313), Expect = 2e-28 Identities = 62/164 (37%), Positives = 93/164 (56%), Gaps = 7/164 (4%) Frame = +1 Query: 49 MDSSTGKSNKLTMAAYTYFVKLIRDEHRKKHPEEQFDFTEFSAKCAEKWKSMKPEERKRF 228 M K + M++Y +FV+ R+EH+KKHP+ +F+EFS KC+E+WK+M +E+ +F Sbjct: 1 MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKF 60 Query: 229 EELASE-----ENDXXXXXXXXXXXXXXXXXXGQPKRAWSAFFYFCDERRPKVRKEHPDW 393 E++A E + PKR SAFF FC E RPK++ EHP Sbjct: 61 EDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGL 120 Query: 394 RVAEVARELGRLWE--ACSDRDRYEKMATLDKERYEKEMEQFRA 519 + +VA++LG +W A D+ YEK A KE+YEK++ +RA Sbjct: 121 SIGDVAKKLGEMWNNTAADDKHPYEKKAAKLKEKYEKDIAAYRA 164
>sp|P52925|HMG2_RAT High mobility group protein 2 (HMG-2) Length = 210 Score = 124 bits (310), Expect = 4e-28 Identities = 57/152 (37%), Positives = 89/152 (58%), Gaps = 7/152 (4%) Frame = +1 Query: 85 MAAYTYFVKLIRDEHRKKHPEEQFDFTEFSAKCAEKWKSMKPEERKRFEELASE-----E 249 M++Y +FV+ R+EH+KKHP+ +F EFS KC+E+WK+M +E+ +FE+LA + Sbjct: 13 MSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDLAKSDKARYD 72 Query: 250 NDXXXXXXXXXXXXXXXXXXGQPKRAWSAFFYFCDERRPKVRKEHPDWRVAEVARELGRL 429 + PKR SAFF FC E RPK++ EHP + + A++LG + Sbjct: 73 REMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEM 132 Query: 430 W--EACSDRDRYEKMATLDKERYEKEMEQFRA 519 W ++ D+ YE+ A KE+YEK++ +RA Sbjct: 133 WSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRA 164
>sp|P26583|HMG2_HUMAN High mobility group protein 2 (HMG-2) Length = 209 Score = 123 bits (309), Expect = 6e-28 Identities = 59/160 (36%), Positives = 93/160 (58%), Gaps = 8/160 (5%) Frame = +1 Query: 85 MAAYTYFVKLIRDEHRKKHPEEQFDFTEFSAKCAEKWKSMKPEERKRFEELASE-----E 249 M++Y +FV+ R+EH+KKHP+ +F EFS KC+E+WK+M +E+ +FE++A + Sbjct: 13 MSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDMAKSDKARYD 72 Query: 250 NDXXXXXXXXXXXXXXXXXXGQPKRAWSAFFYFCDERRPKVRKEHPDWRVAEVARELGRL 429 + PKR SAFF FC E RPK++ EHP + + A++LG + Sbjct: 73 REMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEM 132 Query: 430 W--EACSDRDRYEKMATLDKERYEKEMEQFRA-GNFVAGE 540 W ++ D+ YE+ A KE+YEK++ +RA G AG+ Sbjct: 133 WSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGK 172
>sp|P30681|HMG2_MOUSE High mobility group protein 2 (HMG-2) Length = 210 Score = 123 bits (308), Expect = 8e-28 Identities = 60/160 (37%), Positives = 93/160 (58%), Gaps = 8/160 (5%) Frame = +1 Query: 85 MAAYTYFVKLIRDEHRKKHPEEQFDFTEFSAKCAEKWKSMKPEERKRFEELASE-----E 249 M++Y +FV+ R+EH+KKHP+ +F EFS KC+E+WK+M +E+ +FE+LA + Sbjct: 13 MSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDLAKSDKARYD 72 Query: 250 NDXXXXXXXXXXXXXXXXXXGQPKRAWSAFFYFCDERRPKVRKEHPDWRVAEVARELGRL 429 + PKR SAFF FC E RPK++ EHP + + A++LG + Sbjct: 73 REMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSENRPKIKIEHPGLSIGDTAKKLGEM 132 Query: 430 W--EACSDRDRYEKMATLDKERYEKEMEQFRA-GNFVAGE 540 W ++ D+ YE+ A KE+YEK++ +RA G AG+ Sbjct: 133 WSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGK 172
>sp|P17741|HMG2_PIG High mobility group protein 2 (HMG-2) Length = 210 Score = 123 bits (308), Expect = 8e-28 Identities = 56/152 (36%), Positives = 89/152 (58%), Gaps = 7/152 (4%) Frame = +1 Query: 85 MAAYTYFVKLIRDEHRKKHPEEQFDFTEFSAKCAEKWKSMKPEERKRFEELASE-----E 249 M++Y +FV+ R+EH+KKHP+ +F EFS KC+E+WK+M +E+ +FE++A + Sbjct: 13 MSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDMAKSDKARYD 72 Query: 250 NDXXXXXXXXXXXXXXXXXXGQPKRAWSAFFYFCDERRPKVRKEHPDWRVAEVARELGRL 429 + PKR SAFF FC E RPK++ EHP + + A++LG + Sbjct: 73 REMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEM 132 Query: 430 W--EACSDRDRYEKMATLDKERYEKEMEQFRA 519 W ++ D+ YE+ A KE+YEK++ +RA Sbjct: 133 WSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRA 164
>sp|P26584|HMG2_CHICK High mobility group protein 2 (HMG-2) Length = 207 Score = 122 bits (306), Expect = 1e-27 Identities = 57/152 (37%), Positives = 88/152 (57%), Gaps = 7/152 (4%) Frame = +1 Query: 85 MAAYTYFVKLIRDEHRKKHPEEQFDFTEFSAKCAEKWKSMKPEERKRFEELAS-----EE 249 M++Y YFV+ R+EH+KKHP+ +F EFS KC+E+WK+M +E+ +FEE+A + Sbjct: 13 MSSYAYFVQTCREEHKKKHPDSSVNFAEFSRKCSERWKTMSSKEKGKFEEMAKGDKARYD 72 Query: 250 NDXXXXXXXXXXXXXXXXXXGQPKRAWSAFFYFCDERRPKVRKEHPDWRVAEVARELGRL 429 + PKR SAFF FC E RPK++ +HP + + A++LG + Sbjct: 73 REMKNYVPPKGEKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKNDHPGLSIGDTAKKLGEM 132 Query: 430 W--EACSDRDRYEKMATLDKERYEKEMEQFRA 519 W + D+ YE+ A KE+YEK++ +RA Sbjct: 133 WSEQLAKDKQPYEQKAAKLKEKYEKDIAAYRA 164
Score = 47.4 bits (111), Expect = 5e-05 Identities = 24/71 (33%), Positives = 43/71 (60%), Gaps = 4/71 (5%) Frame = +1 Query: 313 QPKRAWSAFFYFCDERRPKVRKEHPDWRV--AEVARELGRLWEACSDRD--RYEKMATLD 480 +P+ S++ YF R + +K+HPD V AE +R+ W+ S ++ ++E+MA D Sbjct: 8 KPRGKMSSYAYFVQTCREEHKKKHPDSSVNFAEFSRKCSERWKTMSSKEKGKFEEMAKGD 67 Query: 481 KERYEKEMEQF 513 K RY++EM+ + Sbjct: 68 KARYDREMKNY 78
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 78,769,779 Number of Sequences: 369166 Number of extensions: 1368686 Number of successful extensions: 4807 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4530 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4719 length of database: 68,354,980 effective HSP length: 110 effective length of database: 48,034,130 effective search space used: 8598109270 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)