Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_O11
(537 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q09390|HG12_CAEEL High mobility group protein 1.2 69 1e-11
sp|P10103|HMG1_BOVIN High mobility group protein 1 (HMG-1) ... 67 4e-11
sp|P09429|HMG1_HUMAN High mobility group protein 1 (HMG-1) ... 67 4e-11
sp|P63159|HMG1_RAT High mobility group protein 1 (HMG-1) (H... 67 4e-11
sp|P07156|HMG1_CRIGR High mobility group protein 1 (HMG-1) ... 67 4e-11
sp|P12682|HMG1_PIG High mobility group protein 1 (HMG-1) (H... 66 5e-11
sp|P26583|HMG2_HUMAN High mobility group protein 2 (HMG-2) 65 1e-10
sp|P52925|HMG2_RAT High mobility group protein 2 (HMG-2) 65 1e-10
sp|P17741|HMG2_PIG High mobility group protein 2 (HMG-2) 65 1e-10
sp|Q9UGV6|HMG1X_HUMAN High mobility group protein 1-like 10... 64 2e-10
>sp|Q09390|HG12_CAEEL High mobility group protein 1.2
Length = 235
Score = 68.6 bits (166), Expect = 1e-11
Identities = 27/64 (42%), Positives = 45/64 (70%), Gaps = 2/64 (3%)
Frame = +2
Query: 2 AFFYFCDERRPKVRKEHPDWRVAEVARELGRLWEAC--SDRDRYEKMATLDKERYEKEME 175
AFF++ ++RP+++ HPDW+V +VA+ELG++W+ +D YE+ A DK+RY EM
Sbjct: 141 AFFFYSQDKRPEIQAGHPDWKVGQVAQELGKMWKLVPQETKDMYEQKAQADKDRYADEMR 200
Query: 176 QFRA 187
++A
Sbjct: 201 NYKA 204
>sp|P10103|HMG1_BOVIN High mobility group protein 1 (HMG-1) (High mobility group protein
B1)
Length = 215
Score = 66.6 bits (161), Expect = 4e-11
Identities = 30/64 (46%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
Frame = +2
Query: 2 AFFYFCDERRPKVRKEHPDWRVAEVARELGRLWE--ACSDRDRYEKMATLDKERYEKEME 175
AFF FC E RPK++ EHP + +VA++LG +W A D+ YEK A KE+YEK++
Sbjct: 101 AFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIA 160
Query: 176 QFRA 187
+RA
Sbjct: 161 AYRA 164
Score = 43.1 bits (100), Expect = 4e-04
Identities = 26/82 (31%), Positives = 45/82 (54%), Gaps = 4/82 (4%)
Frame = +2
Query: 2 AFFYFCDERRPKVRKEHPDWRV--AEVARELGRLWEACS--DRDRYEKMATLDKERYEKE 169
++ +F R + +K+HPD V +E +++ W+ S ++ ++E MA DK RYE+E
Sbjct: 15 SYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYERE 74
Query: 170 MEQFRAGNFVAGETKRPKLDVN 235
M+ + GETK+ D N
Sbjct: 75 MKTYIPPK---GETKKKFKDPN 93
>sp|P09429|HMG1_HUMAN High mobility group protein 1 (HMG-1) (High mobility group protein
B1)
sp|Q6YKA4|HMG1_CANFA High mobility group protein 1 (HMG-1) (High mobility group protein
B1)
Length = 215
Score = 66.6 bits (161), Expect = 4e-11
Identities = 30/64 (46%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
Frame = +2
Query: 2 AFFYFCDERRPKVRKEHPDWRVAEVARELGRLWE--ACSDRDRYEKMATLDKERYEKEME 175
AFF FC E RPK++ EHP + +VA++LG +W A D+ YEK A KE+YEK++
Sbjct: 101 AFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIA 160
Query: 176 QFRA 187
+RA
Sbjct: 161 AYRA 164
Score = 43.1 bits (100), Expect = 4e-04
Identities = 26/82 (31%), Positives = 45/82 (54%), Gaps = 4/82 (4%)
Frame = +2
Query: 2 AFFYFCDERRPKVRKEHPDWRV--AEVARELGRLWEACS--DRDRYEKMATLDKERYEKE 169
++ +F R + +K+HPD V +E +++ W+ S ++ ++E MA DK RYE+E
Sbjct: 15 SYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYERE 74
Query: 170 MEQFRAGNFVAGETKRPKLDVN 235
M+ + GETK+ D N
Sbjct: 75 MKTYIPPK---GETKKKFKDPN 93
>sp|P63159|HMG1_RAT High mobility group protein 1 (HMG-1) (High mobility group protein
B1) (Amphoterin) (Heparin-binding protein p30)
sp|P63158|HMG1_MOUSE High mobility group protein 1 (HMG-1) (High mobility group protein
B1)
Length = 215
Score = 66.6 bits (161), Expect = 4e-11
Identities = 30/64 (46%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
Frame = +2
Query: 2 AFFYFCDERRPKVRKEHPDWRVAEVARELGRLWE--ACSDRDRYEKMATLDKERYEKEME 175
AFF FC E RPK++ EHP + +VA++LG +W A D+ YEK A KE+YEK++
Sbjct: 101 AFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIA 160
Query: 176 QFRA 187
+RA
Sbjct: 161 AYRA 164
Score = 43.1 bits (100), Expect = 4e-04
Identities = 26/82 (31%), Positives = 45/82 (54%), Gaps = 4/82 (4%)
Frame = +2
Query: 2 AFFYFCDERRPKVRKEHPDWRV--AEVARELGRLWEACS--DRDRYEKMATLDKERYEKE 169
++ +F R + +K+HPD V +E +++ W+ S ++ ++E MA DK RYE+E
Sbjct: 15 SYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYERE 74
Query: 170 MEQFRAGNFVAGETKRPKLDVN 235
M+ + GETK+ D N
Sbjct: 75 MKTYIPPK---GETKKKFKDPN 93
>sp|P07156|HMG1_CRIGR High mobility group protein 1 (HMG-1) (High mobility group protein
B1)
Length = 180
Score = 66.6 bits (161), Expect = 4e-11
Identities = 30/64 (46%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
Frame = +2
Query: 2 AFFYFCDERRPKVRKEHPDWRVAEVARELGRLWE--ACSDRDRYEKMATLDKERYEKEME 175
AFF FC E RPK++ EHP + +VA++LG +W A D+ YEK A KE+YEK++
Sbjct: 66 AFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIA 125
Query: 176 QFRA 187
+RA
Sbjct: 126 AYRA 129
Score = 33.9 bits (76), Expect = 0.26
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 2/58 (3%)
Frame = +2
Query: 68 AEVARELGRLWEACS--DRDRYEKMATLDKERYEKEMEQFRAGNFVAGETKRPKLDVN 235
+E +++ W+ S ++ ++E MA DK RYE+EM+ + GETK+ D N
Sbjct: 4 SEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPK---GETKKKFKDPN 58
>sp|P12682|HMG1_PIG High mobility group protein 1 (HMG-1) (High mobility group protein
B1)
Length = 215
Score = 66.2 bits (160), Expect = 5e-11
Identities = 30/64 (46%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
Frame = +2
Query: 2 AFFYFCDERRPKVRKEHPDWRVAEVARELGRLWE--ACSDRDRYEKMATLDKERYEKEME 175
AFF FC E RPK++ EHP + +VA++LG +W A D+ YEK A KE+YEK++
Sbjct: 101 AFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKHPYEKKAAKLKEKYEKDIA 160
Query: 176 QFRA 187
+RA
Sbjct: 161 AYRA 164
Score = 43.1 bits (100), Expect = 4e-04
Identities = 26/82 (31%), Positives = 45/82 (54%), Gaps = 4/82 (4%)
Frame = +2
Query: 2 AFFYFCDERRPKVRKEHPDWRV--AEVARELGRLWEACS--DRDRYEKMATLDKERYEKE 169
++ +F R + +K+HPD V +E +++ W+ S ++ ++E MA DK RYE+E
Sbjct: 15 SYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYERE 74
Query: 170 MEQFRAGNFVAGETKRPKLDVN 235
M+ + GETK+ D N
Sbjct: 75 MKTYIPPK---GETKKKFKDPN 93
>sp|P26583|HMG2_HUMAN High mobility group protein 2 (HMG-2)
Length = 209
Score = 65.1 bits (157), Expect = 1e-10
Identities = 30/72 (41%), Positives = 46/72 (63%), Gaps = 3/72 (4%)
Frame = +2
Query: 2 AFFYFCDERRPKVRKEHPDWRVAEVARELGRLW--EACSDRDRYEKMATLDKERYEKEME 175
AFF FC E RPK++ EHP + + A++LG +W ++ D+ YE+ A KE+YEK++
Sbjct: 101 AFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIA 160
Query: 176 QFRA-GNFVAGE 208
+RA G AG+
Sbjct: 161 AYRAKGKSEAGK 172
Score = 41.6 bits (96), Expect = 0.001
Identities = 27/84 (32%), Positives = 46/84 (54%), Gaps = 6/84 (7%)
Frame = +2
Query: 2 AFFYFCDERRPKVRKEHPDWRV--AEVARELGRLWEACS--DRDRYEKMATLDKERYEKE 169
++ +F R + +K+HPD V AE +++ W+ S ++ ++E MA DK RY++E
Sbjct: 15 SYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDMAKSDKARYDRE 74
Query: 170 MEQFRAGNFV--AGETKRPKLDVN 235
M+ N+V G+ K K D N
Sbjct: 75 MK-----NYVPPKGDKKGKKKDPN 93
>sp|P52925|HMG2_RAT High mobility group protein 2 (HMG-2)
Length = 210
Score = 64.7 bits (156), Expect = 1e-10
Identities = 27/64 (42%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
Frame = +2
Query: 2 AFFYFCDERRPKVRKEHPDWRVAEVARELGRLW--EACSDRDRYEKMATLDKERYEKEME 175
AFF FC E RPK++ EHP + + A++LG +W ++ D+ YE+ A KE+YEK++
Sbjct: 101 AFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIA 160
Query: 176 QFRA 187
+RA
Sbjct: 161 AYRA 164
Score = 40.4 bits (93), Expect = 0.003
Identities = 26/84 (30%), Positives = 46/84 (54%), Gaps = 6/84 (7%)
Frame = +2
Query: 2 AFFYFCDERRPKVRKEHPDWRV--AEVARELGRLWEACS--DRDRYEKMATLDKERYEKE 169
++ +F R + +K+HPD V AE +++ W+ S ++ ++E +A DK RY++E
Sbjct: 15 SYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDLAKSDKARYDRE 74
Query: 170 MEQFRAGNFV--AGETKRPKLDVN 235
M+ N+V G+ K K D N
Sbjct: 75 MK-----NYVPPKGDKKGKKKDPN 93
>sp|P17741|HMG2_PIG High mobility group protein 2 (HMG-2)
Length = 210
Score = 64.7 bits (156), Expect = 1e-10
Identities = 27/64 (42%), Positives = 42/64 (65%), Gaps = 2/64 (3%)
Frame = +2
Query: 2 AFFYFCDERRPKVRKEHPDWRVAEVARELGRLW--EACSDRDRYEKMATLDKERYEKEME 175
AFF FC E RPK++ EHP + + A++LG +W ++ D+ YE+ A KE+YEK++
Sbjct: 101 AFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIA 160
Query: 176 QFRA 187
+RA
Sbjct: 161 AYRA 164
Score = 41.6 bits (96), Expect = 0.001
Identities = 27/84 (32%), Positives = 46/84 (54%), Gaps = 6/84 (7%)
Frame = +2
Query: 2 AFFYFCDERRPKVRKEHPDWRV--AEVARELGRLWEACS--DRDRYEKMATLDKERYEKE 169
++ +F R + +K+HPD V AE +++ W+ S ++ ++E MA DK RY++E
Sbjct: 15 SYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDMAKSDKARYDRE 74
Query: 170 MEQFRAGNFV--AGETKRPKLDVN 235
M+ N+V G+ K K D N
Sbjct: 75 MK-----NYVPPKGDKKGKKKDPN 93
>sp|Q9UGV6|HMG1X_HUMAN High mobility group protein 1-like 10 (HMG-1L10)
Length = 211
Score = 64.3 bits (155), Expect = 2e-10
Identities = 29/64 (45%), Positives = 41/64 (64%), Gaps = 2/64 (3%)
Frame = +2
Query: 2 AFFYFCDERRPKVRKEHPDWRVAEVARELGRLWE--ACSDRDRYEKMATLDKERYEKEME 175
AFF FC RPK++ EHP + +VA++LG +W A D+ YEK A KE+YEK++
Sbjct: 101 AFFLFCSAYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIA 160
Query: 176 QFRA 187
+RA
Sbjct: 161 AYRA 164
Score = 38.9 bits (89), Expect = 0.008
Identities = 25/79 (31%), Positives = 41/79 (51%), Gaps = 4/79 (5%)
Frame = +2
Query: 11 YFCDERRPKVRKEHPDWRV--AEVARELGRLWEACS--DRDRYEKMATLDKERYEKEMEQ 178
+F R +K+HPD V +E +++ W+ S ++ ++E MA DK YE+EM+
Sbjct: 18 FFGQTCREAHKKKHPDASVNLSEFSKKCSERWKTMSAKEKGKFEDMAKADKAHYEREMKT 77
Query: 179 FRAGNFVAGETKRPKLDVN 235
+ GETK+ D N
Sbjct: 78 YIPPK---GETKKKFKDPN 93
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,012,619
Number of Sequences: 369166
Number of extensions: 809376
Number of successful extensions: 2681
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2582
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2646
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3699545625
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)