Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_H01
(754 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q24537|HMG2_DROME High mobility group protein DSP1 (Dors... 125 9e-29
sp|P10103|HMG1_BOVIN High mobility group protein 1 (HMG-1) ... 125 2e-28
sp|P09429|HMG1_HUMAN High mobility group protein 1 (HMG-1) ... 125 2e-28
sp|P63159|HMG1_RAT High mobility group protein 1 (HMG-1) (H... 125 2e-28
sp|P12682|HMG1_PIG High mobility group protein 1 (HMG-1) (H... 124 2e-28
sp|P52925|HMG2_RAT High mobility group protein 2 (HMG-2) 124 4e-28
sp|P26583|HMG2_HUMAN High mobility group protein 2 (HMG-2) 123 5e-28
sp|P30681|HMG2_MOUSE High mobility group protein 2 (HMG-2) 123 6e-28
sp|P17741|HMG2_PIG High mobility group protein 2 (HMG-2) 123 6e-28
sp|P26584|HMG2_CHICK High mobility group protein 2 (HMG-2) 122 1e-27
>sp|Q24537|HMG2_DROME High mobility group protein DSP1 (Dorsal switch protein 1)
Length = 393
Score = 125 bits (315), Expect = 9e-29
Identities = 63/163 (38%), Positives = 92/163 (56%), Gaps = 13/163 (7%)
Frame = +1
Query: 10 MAAYTYFVKLIRDEHRKKHPEEQFDFTEFSAKCAEKWKSMKPEERKRFEELASEEND--- 180
M AY YFV+ R+EH+KKHP+E F EFS KCAE+WK+M +E+KRF E+A ++
Sbjct: 183 MTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYE 242
Query: 181 --------XXXXXXXXXXXXXXXXXXGQPKRAWSAFFYFCDERRPKVRKEHPDWRVAEVA 336
PKR+ SAFF+FC++ R KV+ +P++ V ++A
Sbjct: 243 AEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIA 302
Query: 337 RELGRLWEACSD--RDRYEKMATLDKERYEKEMEQFRAGNFVA 459
+ELGR W + +YE MA DK RYE+EM +++ +A
Sbjct: 303 KELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYKTSGKIA 345
Score = 48.9 bits (115), Expect = 1e-05
Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 4/71 (5%)
Frame = +1
Query: 238 QPKRAWSAFFYFCDERRPKVRKEHPDWRV--AEVARELGRLWEACSDRD--RYEKMATLD 405
+P+ +A+ YF R + +K+HPD V AE +R+ W+ D++ R+ +MA D
Sbjct: 178 KPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKD 237
Query: 406 KERYEKEMEQF 438
K+RYE EM+ +
Sbjct: 238 KQRYEAEMQNY 248
>sp|P10103|HMG1_BOVIN High mobility group protein 1 (HMG-1) (High mobility group protein
B1)
Length = 215
Score = 125 bits (313), Expect = 2e-28
Identities = 60/152 (39%), Positives = 90/152 (59%), Gaps = 7/152 (4%)
Frame = +1
Query: 10 MAAYTYFVKLIRDEHRKKHPEEQFDFTEFSAKCAEKWKSMKPEERKRFEELASE-----E 174
M++Y +FV+ R+EH+KKHP+ +F+EFS KC+E+WK+M +E+ +FE++A E
Sbjct: 13 MSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYE 72
Query: 175 NDXXXXXXXXXXXXXXXXXXGQPKRAWSAFFYFCDERRPKVRKEHPDWRVAEVARELGRL 354
+ PKR SAFF FC E RPK++ EHP + +VA++LG +
Sbjct: 73 REMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEM 132
Query: 355 WE--ACSDRDRYEKMATLDKERYEKEMEQFRA 444
W A D+ YEK A KE+YEK++ +RA
Sbjct: 133 WNNTAADDKQPYEKKAAKLKEKYEKDIAAYRA 164
>sp|P09429|HMG1_HUMAN High mobility group protein 1 (HMG-1) (High mobility group protein
B1)
sp|Q6YKA4|HMG1_CANFA High mobility group protein 1 (HMG-1) (High mobility group protein
B1)
Length = 215
Score = 125 bits (313), Expect = 2e-28
Identities = 60/152 (39%), Positives = 90/152 (59%), Gaps = 7/152 (4%)
Frame = +1
Query: 10 MAAYTYFVKLIRDEHRKKHPEEQFDFTEFSAKCAEKWKSMKPEERKRFEELASE-----E 174
M++Y +FV+ R+EH+KKHP+ +F+EFS KC+E+WK+M +E+ +FE++A E
Sbjct: 13 MSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYE 72
Query: 175 NDXXXXXXXXXXXXXXXXXXGQPKRAWSAFFYFCDERRPKVRKEHPDWRVAEVARELGRL 354
+ PKR SAFF FC E RPK++ EHP + +VA++LG +
Sbjct: 73 REMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEM 132
Query: 355 WE--ACSDRDRYEKMATLDKERYEKEMEQFRA 444
W A D+ YEK A KE+YEK++ +RA
Sbjct: 133 WNNTAADDKQPYEKKAAKLKEKYEKDIAAYRA 164
>sp|P63159|HMG1_RAT High mobility group protein 1 (HMG-1) (High mobility group protein
B1) (Amphoterin) (Heparin-binding protein p30)
sp|P63158|HMG1_MOUSE High mobility group protein 1 (HMG-1) (High mobility group protein
B1)
Length = 215
Score = 125 bits (313), Expect = 2e-28
Identities = 60/152 (39%), Positives = 90/152 (59%), Gaps = 7/152 (4%)
Frame = +1
Query: 10 MAAYTYFVKLIRDEHRKKHPEEQFDFTEFSAKCAEKWKSMKPEERKRFEELASE-----E 174
M++Y +FV+ R+EH+KKHP+ +F+EFS KC+E+WK+M +E+ +FE++A E
Sbjct: 13 MSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYE 72
Query: 175 NDXXXXXXXXXXXXXXXXXXGQPKRAWSAFFYFCDERRPKVRKEHPDWRVAEVARELGRL 354
+ PKR SAFF FC E RPK++ EHP + +VA++LG +
Sbjct: 73 REMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEM 132
Query: 355 WE--ACSDRDRYEKMATLDKERYEKEMEQFRA 444
W A D+ YEK A KE+YEK++ +RA
Sbjct: 133 WNNTAADDKQPYEKKAAKLKEKYEKDIAAYRA 164
>sp|P12682|HMG1_PIG High mobility group protein 1 (HMG-1) (High mobility group protein
B1)
Length = 215
Score = 124 bits (312), Expect = 2e-28
Identities = 60/152 (39%), Positives = 90/152 (59%), Gaps = 7/152 (4%)
Frame = +1
Query: 10 MAAYTYFVKLIRDEHRKKHPEEQFDFTEFSAKCAEKWKSMKPEERKRFEELASE-----E 174
M++Y +FV+ R+EH+KKHP+ +F+EFS KC+E+WK+M +E+ +FE++A E
Sbjct: 13 MSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYE 72
Query: 175 NDXXXXXXXXXXXXXXXXXXGQPKRAWSAFFYFCDERRPKVRKEHPDWRVAEVARELGRL 354
+ PKR SAFF FC E RPK++ EHP + +VA++LG +
Sbjct: 73 REMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEM 132
Query: 355 WE--ACSDRDRYEKMATLDKERYEKEMEQFRA 444
W A D+ YEK A KE+YEK++ +RA
Sbjct: 133 WNNTAADDKHPYEKKAAKLKEKYEKDIAAYRA 164
>sp|P52925|HMG2_RAT High mobility group protein 2 (HMG-2)
Length = 210
Score = 124 bits (310), Expect = 4e-28
Identities = 57/152 (37%), Positives = 89/152 (58%), Gaps = 7/152 (4%)
Frame = +1
Query: 10 MAAYTYFVKLIRDEHRKKHPEEQFDFTEFSAKCAEKWKSMKPEERKRFEELASE-----E 174
M++Y +FV+ R+EH+KKHP+ +F EFS KC+E+WK+M +E+ +FE+LA +
Sbjct: 13 MSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDLAKSDKARYD 72
Query: 175 NDXXXXXXXXXXXXXXXXXXGQPKRAWSAFFYFCDERRPKVRKEHPDWRVAEVARELGRL 354
+ PKR SAFF FC E RPK++ EHP + + A++LG +
Sbjct: 73 REMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEM 132
Query: 355 W--EACSDRDRYEKMATLDKERYEKEMEQFRA 444
W ++ D+ YE+ A KE+YEK++ +RA
Sbjct: 133 WSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRA 164
>sp|P26583|HMG2_HUMAN High mobility group protein 2 (HMG-2)
Length = 209
Score = 123 bits (309), Expect = 5e-28
Identities = 59/160 (36%), Positives = 93/160 (58%), Gaps = 8/160 (5%)
Frame = +1
Query: 10 MAAYTYFVKLIRDEHRKKHPEEQFDFTEFSAKCAEKWKSMKPEERKRFEELASE-----E 174
M++Y +FV+ R+EH+KKHP+ +F EFS KC+E+WK+M +E+ +FE++A +
Sbjct: 13 MSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDMAKSDKARYD 72
Query: 175 NDXXXXXXXXXXXXXXXXXXGQPKRAWSAFFYFCDERRPKVRKEHPDWRVAEVARELGRL 354
+ PKR SAFF FC E RPK++ EHP + + A++LG +
Sbjct: 73 REMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEM 132
Query: 355 W--EACSDRDRYEKMATLDKERYEKEMEQFRA-GNFVAGE 465
W ++ D+ YE+ A KE+YEK++ +RA G AG+
Sbjct: 133 WSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGK 172
>sp|P30681|HMG2_MOUSE High mobility group protein 2 (HMG-2)
Length = 210
Score = 123 bits (308), Expect = 6e-28
Identities = 60/160 (37%), Positives = 93/160 (58%), Gaps = 8/160 (5%)
Frame = +1
Query: 10 MAAYTYFVKLIRDEHRKKHPEEQFDFTEFSAKCAEKWKSMKPEERKRFEELASE-----E 174
M++Y +FV+ R+EH+KKHP+ +F EFS KC+E+WK+M +E+ +FE+LA +
Sbjct: 13 MSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDLAKSDKARYD 72
Query: 175 NDXXXXXXXXXXXXXXXXXXGQPKRAWSAFFYFCDERRPKVRKEHPDWRVAEVARELGRL 354
+ PKR SAFF FC E RPK++ EHP + + A++LG +
Sbjct: 73 REMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSENRPKIKIEHPGLSIGDTAKKLGEM 132
Query: 355 W--EACSDRDRYEKMATLDKERYEKEMEQFRA-GNFVAGE 465
W ++ D+ YE+ A KE+YEK++ +RA G AG+
Sbjct: 133 WSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGK 172
>sp|P17741|HMG2_PIG High mobility group protein 2 (HMG-2)
Length = 210
Score = 123 bits (308), Expect = 6e-28
Identities = 56/152 (36%), Positives = 89/152 (58%), Gaps = 7/152 (4%)
Frame = +1
Query: 10 MAAYTYFVKLIRDEHRKKHPEEQFDFTEFSAKCAEKWKSMKPEERKRFEELASE-----E 174
M++Y +FV+ R+EH+KKHP+ +F EFS KC+E+WK+M +E+ +FE++A +
Sbjct: 13 MSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDMAKSDKARYD 72
Query: 175 NDXXXXXXXXXXXXXXXXXXGQPKRAWSAFFYFCDERRPKVRKEHPDWRVAEVARELGRL 354
+ PKR SAFF FC E RPK++ EHP + + A++LG +
Sbjct: 73 REMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEM 132
Query: 355 W--EACSDRDRYEKMATLDKERYEKEMEQFRA 444
W ++ D+ YE+ A KE+YEK++ +RA
Sbjct: 133 WSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRA 164
>sp|P26584|HMG2_CHICK High mobility group protein 2 (HMG-2)
Length = 207
Score = 122 bits (306), Expect = 1e-27
Identities = 57/152 (37%), Positives = 88/152 (57%), Gaps = 7/152 (4%)
Frame = +1
Query: 10 MAAYTYFVKLIRDEHRKKHPEEQFDFTEFSAKCAEKWKSMKPEERKRFEELAS-----EE 174
M++Y YFV+ R+EH+KKHP+ +F EFS KC+E+WK+M +E+ +FEE+A +
Sbjct: 13 MSSYAYFVQTCREEHKKKHPDSSVNFAEFSRKCSERWKTMSSKEKGKFEEMAKGDKARYD 72
Query: 175 NDXXXXXXXXXXXXXXXXXXGQPKRAWSAFFYFCDERRPKVRKEHPDWRVAEVARELGRL 354
+ PKR SAFF FC E RPK++ +HP + + A++LG +
Sbjct: 73 REMKNYVPPKGEKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKNDHPGLSIGDTAKKLGEM 132
Query: 355 W--EACSDRDRYEKMATLDKERYEKEMEQFRA 444
W + D+ YE+ A KE+YEK++ +RA
Sbjct: 133 WSEQLAKDKQPYEQKAAKLKEKYEKDIAAYRA 164
Score = 47.4 bits (111), Expect = 4e-05
Identities = 24/71 (33%), Positives = 43/71 (60%), Gaps = 4/71 (5%)
Frame = +1
Query: 238 QPKRAWSAFFYFCDERRPKVRKEHPDWRV--AEVARELGRLWEACSDRD--RYEKMATLD 405
+P+ S++ YF R + +K+HPD V AE +R+ W+ S ++ ++E+MA D
Sbjct: 8 KPRGKMSSYAYFVQTCREEHKKKHPDSSVNFAEFSRKCSERWKTMSSKEKGKFEEMAKGD 67
Query: 406 KERYEKEMEQF 438
K RY++EM+ +
Sbjct: 68 KARYDREMKNY 78
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,061,864
Number of Sequences: 369166
Number of extensions: 1171936
Number of successful extensions: 4314
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4061
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4227
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6873311200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)