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Planaria EST Database

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00858
         (1305 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q05793|PGBM_MOUSE  Basement membrane-specific heparan sul...    60   1e-08
sp|Q06561|UNC52_CAEEL  Basement membrane proteoglycan precur...    57   2e-07
sp|P98160|PGBM_HUMAN  Basement membrane-specific heparan sul...    56   3e-07
sp|P98163|YL_DROME  Putative vitellogenin receptor precursor...    51   8e-06
sp|Q9NZR2|LRP1B_HUMAN  Low-density lipoprotein receptor-rela...    50   2e-05
sp|P98156|VLDLR_MOUSE  Very low-density lipoprotein receptor...    49   2e-05
sp|P98155|VLDLR_HUMAN  Very low-density lipoprotein receptor...    49   2e-05
sp|P98158|LRP2_RAT  Low-density lipoprotein receptor-related...    49   2e-05
sp|Q92673|SORL_HUMAN  Sortilin-related receptor precursor (S...    49   2e-05
sp|Q04833|LRP_CAEEL  Low-density lipoprotein receptor-relate...    49   4e-05

>sp|Q05793|PGBM_MOUSE Basement membrane-specific heparan sulfate proteoglycan core protein
            precursor (HSPG) (Perlecan) (PLC)
          Length = 3707

 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 65/264 (24%), Positives = 102/264 (38%), Gaps = 7/264 (2%)
 Frame = +2

Query: 17   GIYQCIISGRDPSTGQ--TVDLRATFTIQPEFKIGSKIELTEPPGPQIFVR-AGDKRELH 187
            G Y+C +S R  S      V ++ + +  P+  I      T    PQ+  R  G   E H
Sbjct: 2682 GRYRCQVSNRVGSAEAFAQVLVQGSSSNLPDTSIPGGSTPTVQVTPQLETRNIGASVEFH 2741

Query: 188  CEIGVNTGLQGRNAEWYFNGRLMSPNDYSQYNMRILPRLYVSIMILQNIQQMNEGKYECK 367
            C +      +G +  W   G  + P    Q            ++ +QN+ Q  +G Y C+
Sbjct: 2742 CAV---PNERGTHLRWLKEGGQLPPGHSVQDG----------VLRIQNLDQNCQGTYVCQ 2788

Query: 368  VKGETKEAYI---IVMAKSRTIEVNPNEETRRVGDGRPVEFHCRIGGYRTKNRDVVWTFM 538
              G   +A     +++    ++ +N       V  G  VEF C   G       V W   
Sbjct: 2789 AHGPWGQAQATAQLIVQALPSVLINVRTSVHSVVVGHSVEFECLALG--DPKPQVTW--- 2843

Query: 539  SKETGQITPLESRWSRSDDPTADETSFIILQQAELSDAGTYICTEPDTRDTARS-ILNVI 715
            SK  G + P                + I +   EL+DAG Y C   +   T +S +L ++
Sbjct: 2844 SKVGGHLRP----------GIVQSGTIIRIAHVELADAGQYRCAATNAAGTTQSHVLLLV 2893

Query: 716  SDLRIVVTPPIIKLRAGQTATFQC 787
              L  + TPP I++ AG  A F C
Sbjct: 2894 QALPQISTPPEIRVPAGSAAVFPC 2917

 Score = 37.7 bits (86), Expect = 0.073
 Identities = 15/32 (46%), Positives = 17/32 (53%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 1099
            C      C +G CI     CDG+ DC DGSDE
Sbjct: 285  CGPQEASCHSGHCIPRDYLCDGQEDCRDGSDE 316

 Score = 37.4 bits (85), Expect = 0.096
 Identities = 64/282 (22%), Positives = 101/282 (35%), Gaps = 25/282 (8%)
 Frame = +2

Query: 17   GIYQCIISGRD-PSTGQTVDLRATFTIQPEFKIGSKIELTEPPGPQIFVRAGDKRELHCE 193
            G Y C ++G   P    +  L    +    F++ S +   EPP     V+ G      C 
Sbjct: 2309 GEYVCQVAGSSHPEHEASFKLTVPSSQNSSFRLRSPVISIEPPSST--VQQGQDASFKCL 2366

Query: 194  IGVNTGLQGRNAEWYFNGRLMSPNDYSQYNMRILP-------RLYVSIMILQNIQQMNEG 352
            I  + G      EW    + +  N +   N  I+         +  +  +  N+  M + 
Sbjct: 2367 I--HEGAMPIKVEWKIRDQELEDNVHISPNGSIITIVAPGPATMEPTACVASNVYGMAQS 2424

Query: 353  KYECKVKGETKEAYIIVMAKSRTIEVNPNEETRRVGDGRPVEFHCRIGGYRTKNRDVVWT 532
                 V G              T+ V P           PV  H ++G      +D+   
Sbjct: 2425 VVNLSVHGPP------------TVSVLPEG---------PV--HVKMG------KDITLE 2455

Query: 533  FMSKETGQITPLESRWSRSDDPTADE-------TSFIILQQAEL--SDAGTYICTEPDTR 685
             +S    + +P   RW+R   P   E        S  +L+ A +  SDAGTY+C   +  
Sbjct: 2456 CISSGEPRSSP---RWTRLGIPVKLEPRMFGLMNSHAMLKIASVKPSDAGTYVCQAQNAL 2512

Query: 686  DTARSILNVISDLRIVV--TPPI------IKLRAGQTATFQC 787
             TA+  + +I D   V   TP +      + L AG TAT  C
Sbjct: 2513 GTAQKQVELIVDTGTVAPGTPQVQVEESELTLEAGHTATLHC 2554

 Score = 37.4 bits (85), Expect = 0.096
 Identities = 31/122 (25%), Positives = 55/122 (45%), Gaps = 2/122 (1%)
 Frame = +2

Query: 311  SIMILQNIQQMNEGKYECKVKGE--TKEAYIIVMAKSRTIEVNPNEETRRVGDGRPVEFH 484
            +I+ + +++  + G+Y C       T +++++++ ++      P E   RV  G    F 
Sbjct: 2859 TIIRIAHVELADAGQYRCAATNAAGTTQSHVLLLVQALPQISTPPEI--RVPAGSAAVFP 2916

Query: 485  CRIGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDDPTADETSFIILQQAELSDAGTYI 664
            C   GY T    + W   SK  G + P +SR          E + ++L      DAGTY+
Sbjct: 2917 CMASGYPTPA--ITW---SKVDGDLPP-DSRL---------ENNMLMLPSVRPEDAGTYV 2961

Query: 665  CT 670
            CT
Sbjct: 2962 CT 2963

 Score = 37.0 bits (84), Expect = 0.13
 Identities = 40/166 (24%), Positives = 70/166 (42%), Gaps = 13/166 (7%)
 Frame = +2

Query: 329  NIQQMNEGKYECKVKG-----ETKEAYIIVMAKSRTIEVNPNEE-TRRVGDGRPVEFHCR 490
            ++Q  + G Y C  +       ++   ++  A S+ I V   E+ ++ V  G  V F C 
Sbjct: 1734 SVQPSDAGVYICTCRNLIHTSNSRAELLVAEAPSKPIMVTVEEQRSQSVRPGADVTFICT 1793

Query: 491  IGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDDPTADETSFIILQQAELSDAGTYICT 670
                ++    +VWT +         L SR         D    + ++  + SDAGTY+CT
Sbjct: 1794 AKS-KSPAYTLVWTRLHNGK-----LPSR-------AMDFNGILTIRNVQPSDAGTYVCT 1840

Query: 671  EPD--TRDTARSILNV-ISDLRIV----VTPPIIKLRAGQTATFQC 787
              +    D   + L+V +S         + PP + ++ GQ A F+C
Sbjct: 1841 GSNMFAMDQGTATLHVQVSGTSTAPVASIHPPQLTVQPGQQAEFRC 1886

 Score = 36.6 bits (83), Expect = 0.16
 Identities = 46/180 (25%), Positives = 73/180 (40%), Gaps = 20/180 (11%)
 Frame = +2

Query: 323  LQNIQQMNEGKYECKVKGE--TKEAYIIVMAKSRTIEVNPNEETRRVGDGRPVEFHCRIG 496
            L  +   + G+Y C+V G   T EA ++V     TIE +        G  +PV       
Sbjct: 2202 LNRVSPADSGEYSCQVTGSSGTLEASVLV-----TIEASEPSPIPAPGLAQPVYIESS-S 2255

Query: 497  GYRTKNR--DVVWTFMSKETGQITPLESRWSR--SDDPTADET--SFIILQQAELSDAGT 658
             + T+ +  D+      +   Q+T     W +  S  P   +T  S + L Q   +D+G 
Sbjct: 2256 SHLTEGQTVDLKCVVPGQAHAQVT-----WHKRGSSLPARHQTHGSLLRLYQLSPADSGE 2310

Query: 659  YICT---------EPDTRDTARSILNVISDLR---IVVTPPIIKLRAGQTATFQCYVLNG 802
            Y+C          E   + T  S  N    LR   I + PP   ++ GQ A+F+C +  G
Sbjct: 2311 YVCQVAGSSHPEHEASFKLTVPSSQNSSFRLRSPVISIEPPSSTVQQGQDASFKCLIHEG 2370

 Score = 34.7 bits (78), Expect = 0.62
 Identities = 22/72 (30%), Positives = 30/72 (41%), Gaps = 4/72 (5%)
 Frame = +2

Query: 953  CRKGRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDED----QEFCRL 1120
            CR G  S ++     P C      C NG C      CDG  DC D +DE     ++   +
Sbjct: 310  CRDG--SDELGCASPPPCEPNEFACENGHCALKLWRCDGDFDCEDRTDEANCSVKQPGEV 367

Query: 1121 CDPLSKRCETHN 1156
            C P   +C + N
Sbjct: 368  CGPTHFQCVSTN 379

 Score = 34.3 bits (77), Expect = 0.81
 Identities = 41/194 (21%), Positives = 72/194 (37%), Gaps = 5/194 (2%)
 Frame = +2

Query: 146  PQIFVRAGDKRELHCEIGVNTGLQGRNAEWYFNGRLMSPNDYSQYNMRILPRLYVSIMIL 325
            PQ+ V+ G + E  C     TG      EW        P     +N          I+ L
Sbjct: 1872 PQLTVQPGQQAEFRCSA---TGNPTPMLEWIGGPSGQLPAKAQIHN---------GILRL 1919

Query: 326  QNIQQMNEGKYECKVKGETKEAYIIVMAKSR-----TIEVNPNEETRRVGDGRPVEFHCR 490
              I+  ++G+Y C+      +     M +        ++V+P  E  +V +GR V  +CR
Sbjct: 1920 PAIEPSDQGQYLCRALSSAGQHVARAMLQVHGGSGPRVQVSP--ERTQVHEGRTVRLYCR 1977

Query: 491  IGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDDPTADETSFIILQQAELSDAGTYICT 670
              G    +  + W    KE G + P   +            S + L    ++D+G Y+C 
Sbjct: 1978 AAG--VPSASITW---RKEGGSL-PFRHQ---------AHGSRLRLHHMSVADSGEYVCR 2022

Query: 671  EPDTRDTARSILNV 712
              +  D   + + +
Sbjct: 2023 ANNNIDAQETSIMI 2036

>sp|Q06561|UNC52_CAEEL Basement membrane proteoglycan precursor (Perlecan homolog)
            (Uncoordinated protein 52)
          Length = 3375

 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 48/190 (25%), Positives = 69/190 (36%), Gaps = 10/190 (5%)
 Frame = +2

Query: 656  TYICTEPDTRDTARSILNVISDLRIVVTPPIIKLRAGQTATFQCYVLNGGRSADHPDFFM 835
            TY   + D  DT        SD++I V P   ++R G+  +F+C       S      + 
Sbjct: 31   TYQDIDSDDDDT--------SDVQITVFPSEKEVRDGRDVSFECRARTSDNSVYPTVRWA 82

Query: 836  ANGGRASDSQRTTVEKLEAGKVQLT----------YRAVTTNDNGTRFTCRKGRSSADVI 985
              GG    S   +  +L    VQL+          Y   T     T      G       
Sbjct: 83   RVGGPLPSSAHDSGGRLTINPVQLSDAGTYICVSDYNGNTVEARATLSVVSYGPQEVSNG 142

Query: 986  VLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETHNGQN 1165
            +     C A  + C N EC+ +   CDG+ DC D SDE       C  +S+ CE +  + 
Sbjct: 143  LRQAGQCMADEKACGNNECVKNDYVCDGEPDCRDRSDEAN-----CPAISRTCEPNEFKC 197

Query: 1166 PTNNIYQAHW 1195
              N   Q  W
Sbjct: 198  NNNKCVQKMW 207

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 71/252 (28%), Positives = 95/252 (37%), Gaps = 26/252 (10%)
 Frame = +2

Query: 422  IEVNPNEETRRVGDGRPVEFHCRIGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDDP- 598
            I V P+E  + V DGR V F CR    RT +  V  T              RW+R   P 
Sbjct: 47   ITVFPSE--KEVRDGRDVSFECRA---RTSDNSVYPTV-------------RWARVGGPL 88

Query: 599  ---TADETSFIILQQAELSDAGTYICTEPDTRDT--ARSILNVISDLRIVVTPPIIKLRA 763
                 D    + +   +LSDAGTYIC      +T  AR+ L+V+S     V+  +   +A
Sbjct: 89   PSSAHDSGGRLTINPVQLSDAGTYICVSDYNGNTVEARATLSVVSYGPQEVSNGL--RQA 146

Query: 764  GQ-------TATFQC----YVLNGGRSADHPDFFMANGGRASDSQRTTVEKLE------- 889
            GQ           +C    YV +G      PD    +      +   T E  E       
Sbjct: 147  GQCMADEKACGNNECVKNDYVCDG-----EPDCRDRSDEANCPAISRTCEPNEFKCNNNK 201

Query: 890  -AGKVQLTYRAVTTNDNGTRFTCRKGRSSADVIVLVDPICTAGSRLCRN-GECINSAKFC 1063
               K+ L        DN     C    SS+D        C      C +  +C+ S+  C
Sbjct: 202  CVQKMWLCDGDDDCGDNSDELNCNAKPSSSD--------CKPTEFQCHDRRQCVPSSFHC 253

Query: 1064 DGKRDCADGSDE 1099
            DG  DC DGSDE
Sbjct: 254  DGTNDCHDGSDE 265

 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 78/306 (25%), Positives = 124/306 (40%), Gaps = 30/306 (9%)
 Frame = +2

Query: 17   GIYQCIISGRDPSTGQTVDLRATFT----IQPEFKIGSKIELTEPPGPQIFVRAGDKREL 184
            G Y+C  +  D ST  +   R        IQP+          +PP     V  G+   +
Sbjct: 1477 GEYECTSTEPDGSTQLSPPARLNVNQPQAIQPQ---------VDPPVQT--VNEGEPSRI 1525

Query: 185  HCEIGVNTGLQGRNAEWYFNGRLMSPND--YSQYNMRILPRLYVSIMILQNIQQMNEGKY 358
             C +  +  +Q    ++   GR   P    +SQ N+ I PR   S          +E +Y
Sbjct: 1526 RCWVPGHPNIQ---LQFVKRGRRPLPAHARFSQGNLEI-PRTLKS----------DEDEY 1571

Query: 359  ECKVKG-------ETKEAYIIVMAKSRTIEVNPNEETRRVGDGRPVEFHCRIGGYRTKNR 517
             C           E+  A +IV +  R I ++P E+T  V +G P +  C + G+ +   
Sbjct: 1572 ICIATDPTTNRPVESNPARVIVKSPIRPI-IDPAEQT--VPEGSPFKIRCYVPGHPS--- 1625

Query: 518  DVVWTFMSKETGQITPLESRWSRSDDPTADETSFII-LQQAELSDAGTYICT--EPDTRD 688
             V  TF  + +GQ+           +  ADE + ++ +Q+AEL+D G YICT  +PDT  
Sbjct: 1626 -VQLTFR-RVSGQL-----------NEDADENNGLLAVQRAELTDEGDYICTARDPDTGA 1672

Query: 689  TARS------ILNVISDLRI--------VVTPPIIKLRAGQTATFQCYVLNGGRSADHPD 826
               S      + N  +  ++        V+TP    +  G  A  QC V     +A H  
Sbjct: 1673 PIDSTPATVHVTNAAAPPQVEARPPQHPVITPQTQTIPEGDPARIQCTVPGNPSAAQHLS 1732

Query: 827  FFMANG 844
            F   +G
Sbjct: 1733 FERVDG 1738

 Score = 40.8 bits (94), Expect = 0.009
 Identities = 54/255 (21%), Positives = 100/255 (39%), Gaps = 10/255 (3%)
 Frame = +2

Query: 59   GQTVDLRATFTIQPEFKIGSKIELTEPPGPQIFVRAGDKRELHCEIGVNTGLQGRNAEWY 238
            GQ  +   TF  +P   +  ++ + EP   +     GD+    C++   T  +  + EW 
Sbjct: 1113 GQVTNEDITFVQKPHEVL--RVRIMEPK--RQIALPGDRVHWICQVTGYT-TEKIHVEWT 1167

Query: 239  FNGRLMSPNDYSQYNMRILPRLYVSIMILQNIQQMNEGKYECKVKGETKEAYI-IVMAKS 415
              G +  P +   Y+           ++L+ ++  N G+Y C     T+ A    ++  S
Sbjct: 1168 KVGEMSLPPNAKAYD---------GYLVLKGVEAENAGQYRCTATTITQYATDDALLTIS 1218

Query: 416  RTIEVNPNEETRR-----VGDGRPVEFHCRIGGYRTKNRDVVWTFMSKETGQITPLESRW 580
            + I   P +         V +G P  F C + G      D   T+  ++ G   P     
Sbjct: 1219 KRISGRPPQPVIDPPHLVVNEGEPAAFRCWVPGIP----DCQITWHREQLGGPLP----- 1269

Query: 581  SRSDDPTADETSFIILQQAELSDAGTYICTEPDTRDTARSILNVISDLRIVVTPPIIKLR 760
                       + + + Q++L  AG YIC+  +   T +S   V+   + V+ P +  +R
Sbjct: 1270 ----HGVYQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPAVLEVKKPVIPPKVDPIR 1325

Query: 761  ----AGQTATFQCYV 793
                  Q A F+C+V
Sbjct: 1326 QTVDRDQPARFKCWV 1340

 Score = 40.8 bits (94), Expect = 0.009
 Identities = 38/180 (21%), Positives = 71/180 (39%), Gaps = 22/180 (12%)
 Frame = +2

Query: 314  IMILQNIQQMNEGKYECKVKGETKEA---------YIIVMAKSRTIEVNPNE------ET 448
            ++ +Q  +  +EG Y C  +     A         ++   A    +E  P +      +T
Sbjct: 1647 LLAVQRAELTDEGDYICTARDPDTGAPIDSTPATVHVTNAAAPPQVEARPPQHPVITPQT 1706

Query: 449  RRVGDGRPVEFHCRIGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDDPTADETSFIIL 628
            + + +G P    C + G  +  + + +    +  G+  P  S         +D+   + +
Sbjct: 1707 QTIPEGDPARIQCTVPGNPSAAQHLSF---ERVDGKGLPFGS---------SDDRGVLTI 1754

Query: 629  QQAELSDAGTYICT-EPDTRDTAR---SILNVISD---LRIVVTPPIIKLRAGQTATFQC 787
               +L DAG Y+C   P+     +   S LNV  +    R V TPP++ +  G  A F C
Sbjct: 1755 PSTQLQDAGEYVCLYSPENSPPVKTNPSTLNVTPEGTPPRPVATPPLLSVAPGSPARFNC 1814

 Score = 38.9 bits (89), Expect = 0.033
 Identities = 32/134 (23%), Positives = 56/134 (41%), Gaps = 11/134 (8%)
 Frame = +2

Query: 425  EVNPNEETRRVGDGRPVEFHCRIGGYRTKNRDVVWTFMSKETGQITPLESRWSRSD---- 592
            +++P  +T  V D  P +F C + G                       + +WSR D    
Sbjct: 1417 QIDPPNQTVNVND--PAQFRCWVPGQPRA-------------------QLKWSRKDGRPL 1455

Query: 593  -DPTADETSFIILQQAELSDAGTYIC--TEPD----TRDTARSILNVISDLRIVVTPPII 751
             +   +   F+ + +++L DAG Y C  TEPD        AR  +N    ++  V PP+ 
Sbjct: 1456 PNGILERDGFLRIDKSQLHDAGEYECTSTEPDGSTQLSPPARLNVNQPQAIQPQVDPPVQ 1515

Query: 752  KLRAGQTATFQCYV 793
             +  G+ +  +C+V
Sbjct: 1516 TVNEGEPSRIRCWV 1529

 Score = 35.8 bits (81), Expect = 0.28
 Identities = 56/261 (21%), Positives = 89/261 (34%), Gaps = 22/261 (8%)
 Frame = +2

Query: 131  TEPPGPQIFVRAGDKRELHCEIGVNTGLQGRNAEWYFN---GRLMSPNDYSQYNMRILPR 301
            T PPGP++ V  G+  ++ CE     G      EW  +    R   P+D+          
Sbjct: 1979 TNPPGPKLIVTVGEPLQVKCEAFGAPGDPEPEVEWLHDPGPERGDLPDDFKPVT------ 2032

Query: 302  LYVSIMILQNIQQMNEGKYECKVKG----ETKEAYIIVMAKSRTIEVN-PNEETRRVGDG 466
            +    +   N+   N G Y CK        TK  YI V+  SR   V+     ++    G
Sbjct: 2033 ISEQFIRHPNVGLGNAGVYTCKGSSAHATATKNIYIEVVEPSRIATVSILGGSSQWFDQG 2092

Query: 467  RPVEFHCRIGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDD--PT----ADETSFIIL 628
               E  C   G    +R                    W + DD  PT     +E   +  
Sbjct: 2093 EKGELICTATGSSLVDR------------------LEWEKVDDQLPTDVEEHNEPGLLHF 2134

Query: 629  QQAELSDAGTYICTEPDTRDT-------ARSILNVISDLRIVVTPPIIK-LRAGQTATFQ 784
               + S AG Y C      +          S  N   + ++ + PP ++ +  G     +
Sbjct: 2135 PSFKNSYAGEYRCNGYRNNEIIASAAVHVHSSANADDEPKVEIEPPRVRVVSQGDNIVLK 2194

Query: 785  CYVLNGGRSADHPDFFMANGG 847
            C V  G  + +H  + +  GG
Sbjct: 2195 CSV-QGAENGEHFKWALLRGG 2214

 Score = 35.4 bits (80), Expect = 0.36
 Identities = 14/34 (41%), Positives = 20/34 (58%), Gaps = 2/34 (5%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSG--NVRECGGLTYQCSD 1295
            CDG+DDCG+  DE  C+   +  +C    +QC D
Sbjct: 209  CDGDDDCGDNSDELNCNAKPSSSDCKPTEFQCHD 242

 Score = 33.5 bits (75), Expect = 1.4
 Identities = 13/38 (34%), Positives = 21/38 (55%)
 Frame = +3

Query: 1182 IKHTGACDGEDDCGNGFDESRCSGNVRECGGLTYQCSD 1295
            +K+   CDGE DC +  DE+ C    R C    ++C++
Sbjct: 162  VKNDYVCDGEPDCRDRSDEANCPAISRTCEPNEFKCNN 199

 Score = 31.6 bits (70), Expect = 5.3
 Identities = 45/206 (21%), Positives = 65/206 (31%), Gaps = 14/206 (6%)
 Frame = +2

Query: 119  KIELTEPPGPQIFV--------RAGDKRELHCEIGVNTGLQGRNAEWYFNGRLMSPNDYS 274
            ++E+TE   P   V        + G++ +  C   + TG       W        P+D +
Sbjct: 1876 RLEVTEDQEPPTAVVEPRTWNGKPGERHQFRC---ITTGSPTPKITWTGPNGSPLPHDVT 1932

Query: 275  QYNMRILPRLYVSIMILQNIQQMNEGKYECKVK---GETKEAYIIVMAKSRTIEVNPNEE 445
                 IL           N +    G Y C      GE  +   + +  S T++ NP   
Sbjct: 1933 PLEPNILD--------FSNGRSELNGDYTCTASNPIGEASDHGNVNIGPSLTVKTNPPGP 1984

Query: 446  TRRVGDGRPVEFHCR-IGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDD--PTADETS 616
               V  G P++  C   G       +V W           P   R    DD  P      
Sbjct: 1985 KLIVTVGEPLQVKCEAFGAPGDPEPEVEWLH--------DPGPERGDLPDDFKPVTISEQ 2036

Query: 617  FIILQQAELSDAGTYICTEPDTRDTA 694
            FI      L +AG Y C       TA
Sbjct: 2037 FIRHPNVGLGNAGVYTCKGSSAHATA 2062

>sp|P98160|PGBM_HUMAN Basement membrane-specific heparan sulfate proteoglycan core protein
            precursor (HSPG) (Perlecan) (PLC)
          Length = 4391

 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 54/219 (24%), Positives = 87/219 (39%), Gaps = 5/219 (2%)
 Frame = +2

Query: 146  PQIFVRA-GDKRELHCEIGVNTGLQGRNAEWYFNGRLMSPNDYSQYNMRILPRLYVSIMI 322
            PQ+  ++ G   E HC +  + G Q R   W+  G  + P    Q            ++ 
Sbjct: 3406 PQLETKSIGASVEFHCAVPSDRGTQLR---WFKEGGQLPPGHSVQDG----------VLR 3452

Query: 323  LQNIQQMNEGKYECKVKGETKEAYI---IVMAKSRTIEVNPNEETRRVGDGRPVEFHCRI 493
            +QN+ Q  +G Y C+  G   +A     +V+    ++ +N     + V  G  VEF C  
Sbjct: 3453 IQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVEFECLA 3512

Query: 494  GGYRTKNRDVVWTFMSKETGQITPLESRWSRSDDPTADETSFIILQQAELSDAGTYICTE 673
             G       V W   SK  G + P                  + +   EL+DAG Y CT 
Sbjct: 3513 LG--DPKPQVTW---SKVGGHLRP----------GIVQSGGVVRIAHVELADAGQYRCTA 3557

Query: 674  PDTRDTARS-ILNVISDLRIVVTPPIIKLRAGQTATFQC 787
             +   T +S +L ++  L  +  P  +++ AG  A F C
Sbjct: 3558 TNAAGTTQSHVLLLVQALPQISMPQEVRVPAGSAAVFPC 3596

 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 54/248 (21%), Positives = 96/248 (38%), Gaps = 10/248 (4%)
 Frame = +2

Query: 80   ATFTIQPEFKIGSKIELTEPPGPQIFVRAGDKRELHCEIGVNTGLQGRNAEWYFNGRLMS 259
            AT  +Q    + + +    PP  Q+ V+ G   E  C     TG      EW        
Sbjct: 1853 ATLHVQASGTLSAPVVSIHPP--QLTVQPGQLAEFRCSA---TGSPTPTLEWTGGPGGQL 1907

Query: 260  PNDYSQYNMRILPRLYVSIMILQNIQQMNEGKYECKVK---GETKEAYIIVMAKSRTIEV 430
            P            +++  I+ L  ++  ++ +Y C+     G+     ++ +       V
Sbjct: 1908 PAK---------AQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRV 1958

Query: 431  NPNEETRRVGDGRPVEFHCRIGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDDPTADE 610
              + E  +V  GR V  +CR  G    +  + W    KE G + P ++R  R+D  T   
Sbjct: 1959 QVSPERTQVHAGRTVRLYCRAAG--VPSATITWR---KEGGSLPP-QARSERTDIAT--- 2009

Query: 611  TSFIILQQAELSDAGTYICTEPDTRDTARSILNVISDLRIVVTPPIIKLRA-------GQ 769
               +++     +DAG Y+C       TA++ + V+       +PP +K+ +       GQ
Sbjct: 2010 ---LLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQ 2066

Query: 770  TATFQCYV 793
            T    C V
Sbjct: 2067 TLDLNCVV 2074

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 65/261 (24%), Positives = 98/261 (37%), Gaps = 16/261 (6%)
 Frame = +2

Query: 53   STGQTVDLRATFTIQPEFKIGSKIELTEP----PGPQIFVRAGDKRELHCEIGVNTGLQG 220
            ++G   +  A+FT+      GS   L  P      P   V+ G      C I  + G   
Sbjct: 2994 ASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLI--HDGAAP 3051

Query: 221  RNAEWYFNGRLMSPNDYSQYNMRILPRLYVSIMILQNIQQMNEGKYECKVKGETKEAYII 400
             + EW       + N   + N+ I P    SI+ +   +  N G Y C        A  +
Sbjct: 3052 ISLEW------KTRNQELEDNVHISPN--GSIITIVGTRPSNHGTYRCVASNAYGVAQSV 3103

Query: 401  VMAKSR---TIEVNPNEETRRVGDGRPVEFHCRIGGY-RTKNRDVVWTFMSKETGQITPL 568
            V        T+ V P E    V  G+ V   C   G  R+  R   WT +S    +   L
Sbjct: 3104 VNLSVHGPPTVSVLP-EGPVWVKVGKAVTLECVSAGEPRSSAR---WTRISSTPAK---L 3156

Query: 569  ESRWSRSDDPTADETSFIILQQAELSDAGTYICTEPDTRDTARSILNVISDL-------- 724
            E R         D  + + +  A+ SDAGTY+C   +   TA+  + VI D         
Sbjct: 3157 EQRTYG----LMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAP 3212

Query: 725  RIVVTPPIIKLRAGQTATFQC 787
            ++      + + AG TAT +C
Sbjct: 3213 QVQAEEAELTVEAGHTATLRC 3233

 Score = 42.0 bits (97), Expect = 0.004
 Identities = 17/32 (53%), Positives = 18/32 (56%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 1099
            C      CRNG CI     CDG+ DC DGSDE
Sbjct: 285  CGPQEAACRNGHCIPRDYLCDGQEDCEDGSDE 316

 Score = 42.0 bits (97), Expect = 0.004
 Identities = 41/166 (24%), Positives = 71/166 (42%), Gaps = 13/166 (7%)
 Frame = +2

Query: 329  NIQQMNEGKYECKVKG----ETKEAYIIVM-AKSRTIEVNPNEE-TRRVGDGRPVEFHCR 490
            ++Q  + G Y C  +      T  A ++V  A S+ I V   E+ ++ V  G  V F C 
Sbjct: 1735 SVQPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICT 1794

Query: 491  IGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDDPTADETSFIILQQAELSDAGTYICT 670
                ++    +VWT +               +      D    + ++  +LSDAGTY+CT
Sbjct: 1795 AKS-KSPAYTLVWTRLHN------------GKLPTRAMDFNGILTIRNVQLSDAGTYVCT 1841

Query: 671  EPD--TRDTARSILNV-----ISDLRIVVTPPIIKLRAGQTATFQC 787
              +    D   + L+V     +S   + + PP + ++ GQ A F+C
Sbjct: 1842 GSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRC 1887

 Score = 39.7 bits (91), Expect = 0.019
 Identities = 33/142 (23%), Positives = 64/142 (45%), Gaps = 2/142 (1%)
 Frame = +2

Query: 314  IMILQNIQQMNEGKYECKVKGE--TKEAYIIVMAKSRTIEVNPNEETRRVGDGRPVEFHC 487
            ++ + +++  + G+Y C       T +++++++ ++      P E   RV  G    F C
Sbjct: 3539 VVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEV--RVPAGSAAVFPC 3596

Query: 488  RIGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDDPTADETSFIILQQAELSDAGTYIC 667
               GY T   D+ W   SK  G + P +SR          E + ++L      DAGTY+C
Sbjct: 3597 IASGYPTP--DISW---SKLDGSLPP-DSRL---------ENNMLMLPSVRPQDAGTYVC 3641

Query: 668  TEPDTRDTARSILNVISDLRIV 733
            T  + +   ++  ++    R+V
Sbjct: 3642 TATNRQGKVKAFAHLQVPERVV 3663

 Score = 33.5 bits (75), Expect = 1.4
 Identities = 19/57 (33%), Positives = 23/57 (40%), Gaps = 4/57 (7%)
 Frame = +2

Query: 998  PICTAGSRLCRNGECINSAKFCDGKRDCADGSDE----DQEFCRLCDPLSKRCETHN 1156
            P C      C NG C      CDG  DC D +DE     +    +C P   RC + N
Sbjct: 323  PPCEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGPTQFRCVSTN 379

 Score = 32.7 bits (73), Expect = 2.4
 Identities = 27/92 (29%), Positives = 36/92 (39%), Gaps = 6/92 (6%)
 Frame = +2

Query: 530  TFMSKETGQITPLESRWSRSDDPTAD----ETSFIILQQAELSDAGTYIC--TEPDTRDT 691
            T     TG   P    WS+   P       E   +I+ +    D+G YIC  T P     
Sbjct: 3230 TLRCSATGSPAPT-IHWSKLRSPLPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAGHAE 3288

Query: 692  ARSILNVISDLRIVVTPPIIKLRAGQTATFQC 787
            A  IL+V S       P    ++AG+T   QC
Sbjct: 3289 ATIILHVESPPYATTVPEHASVQAGETVQLQC 3320

 Score = 31.6 bits (70), Expect = 5.3
 Identities = 60/296 (20%), Positives = 108/296 (36%), Gaps = 34/296 (11%)
 Frame = +2

Query: 17   GIYQCIISGRDPSTGQTVDLRATFTIQPEFKIGSKIELTEPPG-PQIFVRAGDKR----- 178
            G Y C + G   S+G    L A+  +  E    S + +  P G P I +     R     
Sbjct: 2789 GEYVCRVMG---SSGP---LEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQ 2842

Query: 179  --ELHCEIGVNTGLQGRNAEWYFNGRLMSPNDYSQYNMRILPRLYVSIMILQNIQQMNEG 352
              +L C +    G       W+  G           N+    +++  ++ L  +   + G
Sbjct: 2843 TLDLKCVV---PGQAHAQVTWHKRGG----------NLPARHQVHGPLLRLNQVSPADSG 2889

Query: 353  KYECKVKGE--TKEAYIIVMAKSRTIEVNP----------NEETRRVGDGRPVEFHCRIG 496
            +Y C+V G   T EA ++V  +  +    P             +  V +G+ ++ +C + 
Sbjct: 2890 EYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVP 2949

Query: 497  GYRTKNRDVVWTFMSKETGQITPLESRWSRSDDPTADET--SFIILQQAELSDAGTYIC- 667
            G    +  V W    K  G +            P   +T  S + L     +D+G Y+C 
Sbjct: 2950 GQA--HAQVTWY---KRGGSL------------PARHQTHGSQLRLHLVSPADSGEYVCR 2992

Query: 668  --TEPDTRDTARSILNV---------ISDLRIVVTPPIIKLRAGQTATFQCYVLNG 802
              + P     A   + V         +    I + PP   ++ GQ A+F+C + +G
Sbjct: 2993 AASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDG 3048

>sp|P98163|YL_DROME Putative vitellogenin receptor precursor (Yolkless protein) (YL)
          Length = 1984

 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 26/56 (46%), Positives = 30/56 (53%)
 Frame = +2

Query: 962  GRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDP 1129
            G ++A      D  C AG   CR+G CI  AK CDG+ DC D SDE     RLC P
Sbjct: 76   GGTAAGTPGSADTRCDAGQFQCRDGGCILQAKMCDGRGDCKDSSDELDCDYRLCRP 131

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 24/62 (38%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
 Frame = +2

Query: 962  GRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDE-DQEFCRLCDPLSK 1138
            G +S +++      C  G   C +G CI  +  CDG+ DC+DGSDE D+   R C P  +
Sbjct: 1144 GDNSDELLCEATSRCEPGMFQCGSGSCIAGSWECDGRIDCSDGSDEHDKCVHRSCPPDMQ 1203

Query: 1139 RC 1144
            RC
Sbjct: 1204 RC 1205

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 25/60 (41%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
 Frame = +2

Query: 923  TTNDNGTRFTCRKGRSSADVIVLVDPICTAGSRLCRNG-ECINSAKFCDGKRDCADGSDE 1099
            T   NGT   C +G   AD       +C+     CR+G ECI     CDG++DC DGSDE
Sbjct: 1261 TVRCNGTT-ECPRGEDEADC----GDVCSIYEFKCRSGRECIRREFRCDGQKDCGDGSDE 1315

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 23/64 (35%), Positives = 30/64 (46%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETHNGQNPTNNIY 1183
            C      C NG+C++S+  CDG  DC D SDE      LC+  S RCE    Q  + +  
Sbjct: 1118 CHVHQHGCDNGKCVDSSLVCDGTNDCGDNSDE-----LLCEATS-RCEPGMFQCGSGSCI 1171

Query: 1184 QAHW 1195
               W
Sbjct: 1172 AGSW 1175

 Score = 41.2 bits (95), Expect = 0.007
 Identities = 24/65 (36%), Positives = 32/65 (49%), Gaps = 1/65 (1%)
 Frame = +2

Query: 953  CRKGRSSADVIVLVDPICTAGSRLCRNGE-CINSAKFCDGKRDCADGSDEDQEFCRLCDP 1129
            C  G      + L +P    G  LCRN E C+  ++ CDG  DC+DGSDE        D 
Sbjct: 253  CGDGSDERGCLNLCEP--QKGKFLCRNRETCLTLSEVCDGHSDCSDGSDETDLCHSKPDC 310

Query: 1130 LSKRC 1144
             +K+C
Sbjct: 311  DAKKC 315

 Score = 41.2 bits (95), Expect = 0.007
 Identities = 22/53 (41%), Positives = 29/53 (54%), Gaps = 7/53 (13%)
 Frame = +2

Query: 1025 CRNGECINSAKFCDGKRDCADGSDE---DQEFCR----LCDPLSKRCETHNGQ 1162
            C +GEC+     C+G+RDC D SDE   D+E  R    LC P    C  H+G+
Sbjct: 1035 CHSGECLTMNHRCNGRRDCVDNSDEMNCDEEHRRKPKVLCSPNQFAC--HSGE 1085

 Score = 40.8 bits (94), Expect = 0.009
 Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKF-CDGKRDCADGSDEDQEFCRLCDP 1129
            C     LC NG C+   ++ CDG  DC DGSDE +    LC+P
Sbjct: 227  CPGEGHLCANGRCLRRKQWVCDGVDDCGDGSDE-RGCLNLCEP 268

 Score = 40.0 bits (92), Expect = 0.015
 Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
 Frame = +2

Query: 1001 ICTAGSRLCRNGE-CINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETH 1153
            +C+     C +GE C++  + CD ++DC D SDE  + C   D  SK+C  H
Sbjct: 1073 LCSPNQFACHSGEQCVDKERRCDNRKDCHDHSDE--QHCEKFDK-SKKCHVH 1121

 Score = 36.2 bits (82), Expect = 0.21
 Identities = 18/52 (34%), Positives = 23/52 (44%)
 Frame = +2

Query: 944  RFTCRKGRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDE 1099
            R  C  G    D  V     C    + C  G+C++ +  CDG  DC D SDE
Sbjct: 1180 RIDCSDGSDEHDKCV--HRSCPPDMQRCLLGQCLDRSLVCDGHNDCGDKSDE 1229

 Score = 35.0 bits (79), Expect = 0.48
 Identities = 13/39 (33%), Positives = 22/39 (56%)
 Frame = +2

Query: 1025 CRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKR 1141
            C++GEC++ ++ C+   DC +G DE  +    C   S R
Sbjct: 1347 CQDGECVDLSRVCNNFPDCTNGHDEGPKCATACRSASGR 1385

 Score = 32.3 bits (72), Expect = 3.1
 Identities = 14/34 (41%), Positives = 18/34 (52%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCSDGT 1301
            CDG +DCG+  DE  C    R C    +QC  G+
Sbjct: 1137 CDGTNDCGDNSDELLCEATSR-CEPGMFQCGSGS 1169

 Score = 32.0 bits (71), Expect = 4.0
 Identities = 17/54 (31%), Positives = 22/54 (40%), Gaps = 15/54 (27%)
 Frame = +3

Query: 1182 IKHTGACDGEDDCGNGFDESRC---------------SGNVRECGGLTYQCSDG 1298
            I+    CDG+ DCG+G DE  C               S + R C    + C DG
Sbjct: 1297 IRREFRCDGQKDCGDGSDELSCELEKGHHNQSQIQPWSTSSRSCRPHLFDCQDG 1350

 Score = 30.8 bits (68), Expect = 9.0
 Identities = 11/16 (68%), Positives = 12/16 (75%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRC 1247
            CDG DDCG+G DE  C
Sbjct: 247  CDGVDDCGDGSDERGC 262

>sp|Q9NZR2|LRP1B_HUMAN Low-density lipoprotein receptor-related protein 1B precursor
            (Low-density lipoprotein receptor-related protein-deleted
            in tumor) (LRP-DIT)
          Length = 4599

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 26/61 (42%), Positives = 32/61 (52%), Gaps = 11/61 (18%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDE---------DQEFCR--LCDPLSKRCET 1150
            CT    LC NG+C++S  +CDG  DCADGSDE         DQ  C    C P   +C+ 
Sbjct: 3515 CTLKDFLCANGDCVSSRFWCDGDFDCADGSDERNCETSCSKDQFRCSNGQCIPAKWKCDG 3574

Query: 1151 H 1153
            H
Sbjct: 3575 H 3575

 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 25/62 (40%), Positives = 31/62 (50%)
 Frame = +2

Query: 929  NDNGTRFTCRKGRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQE 1108
            ++NGT  T   G +       +  IC AG   C+N  CI +   CDG  DC DGSDED  
Sbjct: 827  DENGTTCTFNPGEA-------LPHICKAGEFRCKNRHCIQARWKCDGDDDCLDGSDEDSV 879

Query: 1109 FC 1114
             C
Sbjct: 880  NC 881

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 21/46 (45%), Positives = 27/46 (58%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKR 1141
            C +   +C+NG CI S   CD K DC DGSDE    C + + LSK+
Sbjct: 2891 CNSSFFMCKNGRCIPSGGLCDNKDDCGDGSDERN--CHINECLSKK 2934

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 21/62 (33%), Positives = 28/62 (45%)
 Frame = +2

Query: 959  KGRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSK 1138
            K +S   ++   +  C  G + C N  CI   K CDG+ DC D SDE       C  +  
Sbjct: 2537 KDKSDEKLLYCENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDCKVSTCATVEF 2596

Query: 1139 RC 1144
            RC
Sbjct: 2597 RC 2598

 Score = 41.6 bits (96), Expect = 0.005
 Identities = 18/40 (45%), Positives = 24/40 (60%)
 Frame = +3

Query: 1182 IKHTGACDGEDDCGNGFDESRCSGNVRECGGLTYQCSDGT 1301
            I H   CDGE+DCG+  DE  C   V  C  + ++C+DGT
Sbjct: 2565 IPHGKLCDGENDCGDNSDELDC--KVSTCATVEFRCADGT 2602

 Score = 40.8 bits (94), Expect = 0.009
 Identities = 23/56 (41%), Positives = 24/56 (42%), Gaps = 9/56 (16%)
 Frame = +2

Query: 1004 CTAGSRLCRN---------GECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRC 1144
            C    RLC +         G CIN A  CDG  DC D SDED     LC P    C
Sbjct: 1088 CNGTIRLCDHKTKFSCWSTGRCINKAWVCDGDIDCEDQSDEDDCDSFLCGPPKHPC 1143

 Score = 40.4 bits (93), Expect = 0.011
 Identities = 15/34 (44%), Positives = 24/34 (70%)
 Frame = +2

Query: 998  PICTAGSRLCRNGECINSAKFCDGKRDCADGSDE 1099
            P C++   +C +  CI+++  C+G+ DCADGSDE
Sbjct: 3592 PTCSSREYICASDGCISASLKCNGEYDCADGSDE 3625

 Score = 39.7 bits (91), Expect = 0.019
 Identities = 18/49 (36%), Positives = 24/49 (48%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCET 1150
            C+     C NG+CI +   CDG  DC  G DE     + C+P S  C +
Sbjct: 3553 CSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDE-----KSCEPASPTCSS 3596

 Score = 39.3 bits (90), Expect = 0.025
 Identities = 17/33 (51%), Positives = 22/33 (66%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCSDG 1298
            CD +DDCG+G DES   G  R+CG   + C+DG
Sbjct: 2824 CDHDDDCGDGSDESPQCG-YRQCGTEEFSCADG 2855

 Score = 38.5 bits (88), Expect = 0.043
 Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 2/55 (3%)
 Frame = +2

Query: 1001 ICTAGSRLCRNGE--CINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETHNG 1159
            +C      C N    C+   K C+GK+DC DGSDE      LCD     C  +NG
Sbjct: 1135 LCGPPKHPCANDTSVCLQPEKLCNGKKDCPDGSDEGY----LCD----ECSLNNG 1181

 Score = 38.5 bits (88), Expect = 0.043
 Identities = 24/67 (35%), Positives = 29/67 (43%), Gaps = 13/67 (19%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDE---DQEFC----------RLCDPLSKRC 1144
            C  G   C  G C   A  CDG+ DC D SDE   D   C          + C P++ RC
Sbjct: 3357 CQPGRFQCGTGLCALPAFICDGENDCGDNSDELNCDTHVCLSGQFKCTKNQKCIPVNLRC 3416

Query: 1145 ETHNGQN 1165
               NGQ+
Sbjct: 3417 ---NGQD 3420

 Score = 38.5 bits (88), Expect = 0.043
 Identities = 17/38 (44%), Positives = 19/38 (50%)
 Frame = +2

Query: 1001 ICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFC 1114
            IC A   LC N  C      CDG+ DC D SDE  + C
Sbjct: 3673 ICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMC 3710

 Score = 38.1 bits (87), Expect = 0.056
 Identities = 24/66 (36%), Positives = 27/66 (40%), Gaps = 15/66 (22%)
 Frame = +2

Query: 1004 CTAGSRL-CRNGECINSAKFCDGKRDCADGSDEDQEFC--------------RLCDPLSK 1138
            C A S   C NGECI+    CDG   C D SDE   +C              R C P  K
Sbjct: 2510 CNAYSEFECGNGECIDYQLTCDGIPHCKDKSDEKLLYCENRSCRRGFKPCYNRRCIPHGK 2569

Query: 1139 RCETHN 1156
             C+  N
Sbjct: 2570 LCDGEN 2575

 Score = 37.7 bits (86), Expect = 0.073
 Identities = 14/26 (53%), Positives = 18/26 (69%)
 Frame = +2

Query: 1022 LCRNGECINSAKFCDGKRDCADGSDE 1099
            +C++G CI+S   CD   DC DGSDE
Sbjct: 974  VCKSGRCISSKWHCDSDDDCGDGSDE 999

 Score = 37.4 bits (85), Expect = 0.096
 Identities = 28/99 (28%), Positives = 36/99 (36%), Gaps = 15/99 (15%)
 Frame = +2

Query: 941  TRFTCRKGR---------------SSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKR 1075
            T+F C+ GR                 +D +  V   C      C +G CI     CDG  
Sbjct: 971  TQFVCKSGRCISSKWHCDSDDDCGDGSDEVGCVHS-CFDNQFRCSSGRCIPGHWACDGDN 1029

Query: 1076 DCADGSDEDQEFCRLCDPLSKRCETHNGQNPTNNIYQAH 1192
            DC D SDE Q  C        + E H+      N +Q H
Sbjct: 1030 DCGDFSDEAQINC-------TKEEIHSPAGCNGNEFQCH 1061

 Score = 37.4 bits (85), Expect = 0.096
 Identities = 15/40 (37%), Positives = 19/40 (47%)
 Frame = +2

Query: 995  DPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFC 1114
            D  C+     C   +CI+    CDG+ DC DG DE    C
Sbjct: 2717 DSSCSWNQFACSAQKCISKHWICDGEDDCGDGLDESDSIC 2756

 Score = 37.4 bits (85), Expect = 0.096
 Identities = 21/52 (40%), Positives = 22/52 (42%)
 Frame = +2

Query: 1040 CINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETHNGQNPTNNIYQAHW 1195
            CI+    CD   DCAD SDE       CD   K C  H  Q   NN    HW
Sbjct: 3449 CISKLWVCDEDPDCADASDEAN-----CD--KKTCGPHEFQCKNNNCIPDHW 3493

 Score = 36.6 bits (83), Expect = 0.16
 Identities = 19/48 (39%), Positives = 24/48 (50%), Gaps = 3/48 (6%)
 Frame = +2

Query: 1004 CTAGSRLCR-NGECINSAKFCDGKRDCADGSDED--QEFCRLCDPLSK 1138
            C      C  +G C+     CDG++DC DGSDE       RLCD  +K
Sbjct: 1053 CNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKGCNGTIRLCDHKTK 1100

 Score = 36.2 bits (82), Expect = 0.21
 Identities = 13/23 (56%), Positives = 16/23 (69%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVREC 1268
            CDGE DC +G DE  C+G +R C
Sbjct: 1073 CDGEKDCEDGSDEKGCNGTIRLC 1095

 Score = 36.2 bits (82), Expect = 0.21
 Identities = 13/25 (52%), Positives = 17/25 (68%)
 Frame = +2

Query: 1025 CRNGECINSAKFCDGKRDCADGSDE 1099
            C +G CI +   CDG++DC DG DE
Sbjct: 2689 CPSGRCILNTWICDGQKDCEDGRDE 2713

 Score = 35.8 bits (81), Expect = 0.28
 Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
 Frame = +2

Query: 1001 ICTAGSRLCRNG-ECINSAKFCDGKRDCADGSDEDQEFC 1114
            +C  G  LC +   C++ +  CDG  DC D SDE  + C
Sbjct: 31   LCDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTC 69

 Score = 35.8 bits (81), Expect = 0.28
 Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 5/39 (12%)
 Frame = +3

Query: 1194 GACDGEDDCGNGFDESRCSGNVREC-----GGLTYQCSD 1295
            G CD +DDCG+G DE  C  ++ EC      G +  C D
Sbjct: 2908 GLCDNKDDCGDGSDERNC--HINECLSKKVSGCSQDCQD 2944

 Score = 35.4 bits (80), Expect = 0.36
 Identities = 15/49 (30%), Positives = 19/49 (38%)
 Frame = +2

Query: 968  SSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFC 1114
            S  D +   +  C      C+N  CI     CDG  DC    DE  + C
Sbjct: 874  SDEDSVNCFNHSCPDDQFKCQNNRCIPKRWLCDGANDCGSNEDESNQTC 922

 Score = 35.4 bits (80), Expect = 0.36
 Identities = 18/47 (38%), Positives = 23/47 (48%), Gaps = 2/47 (4%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRL--CDPLSK 1138
            C      C NG CI  A  CD + DC D +DE    C    C+PL++
Sbjct: 927  CQVDQFSCGNGRCIPRAWLCDREDDCGDQTDE-MASCEFPTCEPLTQ 972

 Score = 35.4 bits (80), Expect = 0.36
 Identities = 19/50 (38%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRL-CDPLSKRCET 1150
            CTA    C+  +CI     CD   DC DGSDE  +     C P   +C T
Sbjct: 3317 CTASQFRCKTDKCIPFWWKCDTVDDCGDGSDEPDDCPEFRCQPGRFQCGT 3366

 Score = 35.0 bits (79), Expect = 0.48
 Identities = 15/33 (45%), Positives = 19/33 (57%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCSDG 1298
            CD +DDCG+G DE  C   V  C    ++CS G
Sbjct: 987  CDSDDDCGDGSDEVGC---VHSCFDNQFRCSSG 1016

 Score = 35.0 bits (79), Expect = 0.48
 Identities = 14/30 (46%), Positives = 16/30 (53%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQC 1289
            CDGEDDCG+G DES        C    + C
Sbjct: 2739 CDGEDDCGDGLDESDSICGAITCAADMFSC 2768

 Score = 34.3 bits (77), Expect = 0.81
 Identities = 14/35 (40%), Positives = 17/35 (48%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQE 1108
            C   + +C N  CI     CD   DC DGSDE  +
Sbjct: 2805 CDENAFMCHNKVCIPKQFVCDHDDDCGDGSDESPQ 2839

 Score = 33.9 bits (76), Expect = 1.1
 Identities = 15/33 (45%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
 Frame = +2

Query: 1004 CTAGSRLCRNGE-CINSAKFCDGKRDCADGSDE 1099
            C A    C+    C+     CDG+RDC DGSDE
Sbjct: 2761 CAADMFSCQGSRACVPRHWLCDGERDCPDGSDE 2793

 Score = 33.9 bits (76), Expect = 1.1
 Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 3/37 (8%)
 Frame = +2

Query: 1025 CRNGECINSAKFCDGKRDCADGSDEDQ---EFCRLCD 1126
            C+N  CI     CD + DC+D SDE+    + C L D
Sbjct: 3483 CKNNNCIPDHWRCDSQNDCSDNSDEENCKPQTCTLKD 3519

 Score = 33.9 bits (76), Expect = 1.1
 Identities = 18/53 (33%), Positives = 22/53 (41%), Gaps = 1/53 (1%)
 Frame = +2

Query: 947  FTCRKGRSSADVIVLVDPICTAGSRLCRN-GECINSAKFCDGKRDCADGSDED 1102
            + C  G    D +      C      C+N   CI     CDG  DC DGSDE+
Sbjct: 3617 YDCADGSDEMDCVTE----CKEDQFRCKNKAHCIPIRWLCDGIHDCVDGSDEE 3665

 Score = 33.9 bits (76), Expect = 1.1
 Identities = 19/48 (39%), Positives = 22/48 (45%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCE 1147
            C      C N +CI     CD   DC DGSDE  + CR+  P    CE
Sbjct: 3762 CKKDEFACSNKKCIPMDLQCDRLDDCGDGSDE--QGCRIA-PTEYTCE 3806

 Score = 32.3 bits (72), Expect = 3.1
 Identities = 13/33 (39%), Positives = 18/33 (54%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCSDG 1298
            CDG +DCG+  DES  +   R C    + C +G
Sbjct: 905  CDGANDCGSNEDESNQTCTARTCQVDQFSCGNG 937

 Score = 32.3 bits (72), Expect = 3.1
 Identities = 14/35 (40%), Positives = 20/35 (57%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCSDGTK 1304
            CDGE+DCG+  DE  C  +V  C    ++C+   K
Sbjct: 3376 CDGENDCGDNSDELNCDTHV--CLSGQFKCTKNQK 3408

 Score = 32.3 bits (72), Expect = 3.1
 Identities = 13/27 (48%), Positives = 17/27 (62%), Gaps = 1/27 (3%)
 Frame = +2

Query: 1025 CRNGE-CINSAKFCDGKRDCADGSDED 1102
            CRN   C+ S + C+G  +C D SDED
Sbjct: 3723 CRNNRICLQSEQMCNGIDECGDNSDED 3749

 Score = 32.0 bits (71), Expect = 4.0
 Identities = 17/51 (33%), Positives = 25/51 (49%), Gaps = 1/51 (1%)
 Frame = +2

Query: 1001 ICTAGSRLC-RNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCET 1150
            +C +G   C +N +CI     C+G+ DC D  DE       C P   +C+T
Sbjct: 3395 VCLSGQFKCTKNQKCIPVNLRCNGQDDCGDEEDERDCPENSCSPDYFQCKT 3445

 Score = 31.6 bits (70), Expect = 5.3
 Identities = 13/33 (39%), Positives = 18/33 (54%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCSDG 1298
            CDG+ DC +G DE  C      C    ++CS+G
Sbjct: 3534 CDGDFDCADGSDERNCE---TSCSKDQFRCSNG 3563

 Score = 31.6 bits (70), Expect = 5.3
 Identities = 15/34 (44%), Positives = 16/34 (47%), Gaps = 1/34 (2%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQC-SDG 1298
            CDG +DC  G DE  C      C    Y C SDG
Sbjct: 3572 CDGHEDCKYGEDEKSCEPASPTCSSREYICASDG 3605

 Score = 31.2 bits (69), Expect = 6.9
 Identities = 14/37 (37%), Positives = 21/37 (56%), Gaps = 6/37 (16%)
 Frame = +3

Query: 1197 ACDGEDDCGNGFDESRCSGNVRE------CGGLTYQC 1289
            ACDG++DCG+  DE++ +    E      C G  +QC
Sbjct: 1024 ACDGDNDCGDFSDEAQINCTKEEIHSPAGCNGNEFQC 1060

 Score = 30.8 bits (68), Expect = 9.0
 Identities = 14/42 (33%), Positives = 21/42 (50%)
 Frame = +2

Query: 1037 ECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETHNGQ 1162
            +C++ ++ C+G  DC DG DE       C  L   C+  N Q
Sbjct: 89   KCVHLSQLCNGVLDCPDGYDEGVH----CQELLSNCQQLNCQ 126

 Score = 30.8 bits (68), Expect = 9.0
 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 1/37 (2%)
 Frame = +3

Query: 1191 TGACDGEDDCGNGFDESRCS-GNVRECGGLTYQCSDG 1298
            T  CDG +DCG+  DE +C   N  +C    + C  G
Sbjct: 2656 TWICDGSNDCGDYSDELKCPVQNKHKCEENYFSCPSG 2692

 Score = 30.8 bits (68), Expect = 9.0
 Identities = 11/18 (61%), Positives = 13/18 (72%)
 Frame = +3

Query: 1188 HTGACDGEDDCGNGFDES 1241
            H   CDGEDDCG+  DE+
Sbjct: 3689 HFWVCDGEDDCGDNSDEA 3706

>sp|P98156|VLDLR_MOUSE Very low-density lipoprotein receptor precursor (VLDL receptor)
          Length = 873

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 16/78 (20%)
 Frame = +2

Query: 992  VDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRL----------------C 1123
            V   C     +C+NG+C+ +   CDG  DC DGSDE  E C +                C
Sbjct: 68   VKKTCAESDFVCKNGQCVPNRWQCDGDPDCEDGSDESPEQCHMRTCRINEISCGARSTQC 127

Query: 1124 DPLSKRCETHNGQNPTNN 1177
             P+S RC+   G+N  +N
Sbjct: 128  IPVSWRCD---GENDCDN 142

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 20/49 (40%), Positives = 28/49 (57%)
 Frame = +2

Query: 1013 GSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETHNG 1159
            G   CR+GECI+ +K CD ++DC D SDE  + C +       C  +NG
Sbjct: 322  GKFKCRSGECIDMSKVCDQEQDCRDWSDEPLKECHI-----NECLVNNG 365

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 21/48 (43%), Positives = 23/48 (47%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCE 1147
            C      C +GECI+    CDG  DC DGSDE     R C P    CE
Sbjct: 239  CPTSEIQCGSGECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECE 286

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 22/53 (41%), Positives = 25/53 (47%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETHNGQ 1162
            C +    C NG CI     CDG  DCADGSDE     + C      C+  NGQ
Sbjct: 33   CDSSQFQCTNGRCITLLWKCDGDEDCADGSDEKNCVKKTCAESDFVCK--NGQ 83

 Score = 40.8 bits (94), Expect = 0.009
 Identities = 26/98 (26%), Positives = 33/98 (33%), Gaps = 15/98 (15%)
 Frame = +2

Query: 947  FTCRKGR---------------SSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDC 1081
            FTC  GR                 +D +    P C A    C    CI  +  CD   DC
Sbjct: 159  FTCSSGRCVSRNFVCNGQDDCDDGSDELDCAPPTCGAHEFQCSTSSCIPLSWVCDDDADC 218

Query: 1082 ADGSDEDQEFCRLCDPLSKRCETHNGQNPTNNIYQAHW 1195
            +D SDE  E C     +  +C T   Q  +       W
Sbjct: 219  SDQSDESLEQCGRQPVIHTKCPTSEIQCGSGECIHKKW 256

 Score = 39.7 bits (91), Expect = 0.019
 Identities = 20/64 (31%), Positives = 28/64 (43%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETHNGQNPTNNIY 1183
            C+A    C +G C++    C+G+ DC DGSDE        D     C  H  Q  T++  
Sbjct: 154  CSADEFTCSSGRCVSRNFVCNGQDDCDDGSDE-------LDCAPPTCGAHEFQCSTSSCI 206

Query: 1184 QAHW 1195
               W
Sbjct: 207  PLSW 210

 Score = 39.7 bits (91), Expect = 0.019
 Identities = 16/45 (35%), Positives = 24/45 (53%)
 Frame = +2

Query: 965  RSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDE 1099
            +  +D +      C      C +G CI+ ++ C+G RDC DGSDE
Sbjct: 265  KDGSDEVNCPSRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDE 309

 Score = 37.4 bits (85), Expect = 0.096
 Identities = 17/33 (51%), Positives = 20/33 (60%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCSDG 1298
            CDGE+DC NG DE  C GN+  C    + CS G
Sbjct: 134  CDGENDCDNGEDEENC-GNI-TCSADEFTCSSG 164

 Score = 33.5 bits (75), Expect = 1.4
 Identities = 14/31 (45%), Positives = 19/31 (61%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCS 1292
            C+G+DDC +G DE  C+     CG   +QCS
Sbjct: 173  CNGQDDCDDGSDELDCAPPT--CGAHEFQCS 201

 Score = 33.5 bits (75), Expect = 1.4
 Identities = 14/34 (41%), Positives = 19/34 (55%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCSDGT 1301
            CDG+ DC +G DE  C    R C    ++C DG+
Sbjct: 258  CDGDPDCKDGSDEVNCPS--RTCRPDQFECEDGS 289

 Score = 31.6 bits (70), Expect = 5.3
 Identities = 12/33 (36%), Positives = 18/33 (54%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCSDG 1298
            CDG++DC +G DE  C    + C    + C +G
Sbjct: 52   CDGDEDCADGSDEKNCV--KKTCAESDFVCKNG 82

>sp|P98155|VLDLR_HUMAN Very low-density lipoprotein receptor precursor (VLDL receptor)
          Length = 873

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 25/71 (35%), Positives = 31/71 (43%), Gaps = 16/71 (22%)
 Frame = +2

Query: 992  VDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRL----------------C 1123
            V   C     +C NG+C+ S   CDG  DC DGSDE  E C +                C
Sbjct: 68   VKKTCAESDFVCNNGQCVPSRWKCDGDPDCEDGSDESPEQCHMRTCRIHEISCGAHSTQC 127

Query: 1124 DPLSKRCETHN 1156
             P+S RC+  N
Sbjct: 128  IPVSWRCDGEN 138

 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 22/48 (45%), Positives = 24/48 (50%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCE 1147
            C A    C +GECI+    CDG  DC DGSDE     R C P    CE
Sbjct: 239  CPASEIQCGSGECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECE 286

 Score = 41.6 bits (96), Expect = 0.005
 Identities = 19/49 (38%), Positives = 28/49 (57%)
 Frame = +2

Query: 1013 GSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETHNG 1159
            G   CR+GECI+ +K C+ ++DC D SDE  + C +       C  +NG
Sbjct: 322  GKFKCRSGECIDISKVCNQEQDCRDWSDEPLKECHI-----NECLVNNG 365

 Score = 40.0 bits (92), Expect = 0.015
 Identities = 21/53 (39%), Positives = 23/53 (43%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETHNGQ 1162
            C      C NG CI     CDG  DC DGSDE     + C      C  +NGQ
Sbjct: 33   CEPSQFQCTNGRCITLLWKCDGDEDCVDGSDEKNCVKKTCAESDFVC--NNGQ 83

 Score = 39.7 bits (91), Expect = 0.019
 Identities = 16/45 (35%), Positives = 24/45 (53%)
 Frame = +2

Query: 965  RSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDE 1099
            +  +D +      C      C +G CI+ ++ C+G RDC DGSDE
Sbjct: 265  KDGSDEVNCPSRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDE 309

 Score = 39.3 bits (90), Expect = 0.025
 Identities = 20/64 (31%), Positives = 28/64 (43%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETHNGQNPTNNIY 1183
            C+     C +G CI+    C+G+ DC+DGSDE        D     C  H  Q  T++  
Sbjct: 154  CSPDEFTCSSGRCISRNFVCNGQDDCSDGSDE-------LDCAPPTCGAHEFQCSTSSCI 206

Query: 1184 QAHW 1195
               W
Sbjct: 207  PISW 210

 Score = 38.9 bits (89), Expect = 0.033
 Identities = 25/98 (25%), Positives = 32/98 (32%), Gaps = 15/98 (15%)
 Frame = +2

Query: 947  FTCRKGR---------------SSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDC 1081
            FTC  GR                 +D +    P C A    C    CI  +  CD   DC
Sbjct: 159  FTCSSGRCISRNFVCNGQDDCSDGSDELDCAPPTCGAHEFQCSTSSCIPISWVCDDDADC 218

Query: 1082 ADGSDEDQEFCRLCDPLSKRCETHNGQNPTNNIYQAHW 1195
            +D SDE  E C     +  +C     Q  +       W
Sbjct: 219  SDQSDESLEQCGRQPVIHTKCPASEIQCGSGECIHKKW 256

 Score = 34.7 bits (78), Expect = 0.62
 Identities = 16/33 (48%), Positives = 20/33 (60%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCSDG 1298
            CDGE+DC +G DE  C GN+  C    + CS G
Sbjct: 134  CDGENDCDSGEDEENC-GNI-TCSPDEFTCSSG 164

 Score = 34.3 bits (77), Expect = 0.81
 Identities = 15/37 (40%), Positives = 20/37 (54%)
 Frame = +3

Query: 1182 IKHTGACDGEDDCGNGFDESRCSGNVRECGGLTYQCS 1292
            I     C+G+DDC +G DE  C+     CG   +QCS
Sbjct: 167  ISRNFVCNGQDDCSDGSDELDCAPPT--CGAHEFQCS 201

 Score = 33.5 bits (75), Expect = 1.4
 Identities = 14/34 (41%), Positives = 19/34 (55%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCSDGT 1301
            CDG+ DC +G DE  C    R C    ++C DG+
Sbjct: 258  CDGDPDCKDGSDEVNCPS--RTCRPDQFECEDGS 289

 Score = 30.8 bits (68), Expect = 9.0
 Identities = 12/33 (36%), Positives = 19/33 (57%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCSDG 1298
            CDG++DC +G DE  C    + C    + C++G
Sbjct: 52   CDGDEDCVDGSDEKNCV--KKTCAESDFVCNNG 82

>sp|P98158|LRP2_RAT Low-density lipoprotein receptor-related protein 2 precursor
            (Megalin) (Glycoprotein 330) (gp330)
          Length = 4660

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 22/64 (34%), Positives = 30/64 (46%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETHNGQNPTNNIY 1183
            C  G   CR+G C +    C+ ++DCADGSDED+  C        RCE++  Q       
Sbjct: 3555 CRLGQFQCRDGNCTSPQALCNARQDCADGSDEDRVLCE-----HHRCESNEWQCANKRCI 3609

Query: 1184 QAHW 1195
               W
Sbjct: 3610 PQSW 3613

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 27/82 (32%), Positives = 32/82 (39%), Gaps = 1/82 (1%)
 Frame = +2

Query: 953  CRKGRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQ-EFCRLCDP 1129
            C  G    D        C A    C NG CI+    CDG  DC D SDEDQ   C L + 
Sbjct: 2891 CADGSDEPDTCGHSVNTCRASQFQCDNGRCISGNWVCDGDNDCGDMSDEDQRHHCELQNC 2950

Query: 1130 LSKRCETHNGQNPTNNIYQAHW 1195
             S +    N + P       +W
Sbjct: 2951 SSTQFTCVNSRPPNRRCIPQYW 2972

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 19/44 (43%), Positives = 22/44 (50%)
 Frame = +2

Query: 998  PICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDP 1129
            P C A    C+NG CI     CD   DC DGSDE +  C   +P
Sbjct: 3032 PPCHANQFTCQNGRCIPRFFVCDEDNDCGDGSDEQEHLCHTPEP 3075

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 18/37 (48%), Positives = 21/37 (56%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFC 1114
            C A    C+N  CI S   CDG+ DC DGSDE+   C
Sbjct: 3844 CPAAMFECKNHVCIQSFWICDGENDCVDGSDEEIHLC 3880

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 20/57 (35%), Positives = 26/57 (45%)
 Frame = +2

Query: 1025 CRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETHNGQNPTNNIYQAHW 1195
            C N  C+   + C+G  DC DGSDE +E CR   P  K C     +    N    H+
Sbjct: 3893 CDNSRCVYGHQLCNGVDDCGDGSDEKEEHCR--KPTHKPCTDTEYKCSNGNCISQHY 3947

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 20/44 (45%), Positives = 23/44 (52%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLS 1135
            C+A    C NG+CI S   CD   DC DGSDE       CD L+
Sbjct: 108  CSAQQMTCSNGQCIPSEYRCDHVSDCPDGSDERNCHYPTCDQLT 151

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 22/46 (47%), Positives = 28/46 (60%), Gaps = 5/46 (10%)
 Frame = +2

Query: 998  PICTAGSRLCRNGE-CINSAKFCDGKRDCADGSDE----DQEFCRL 1120
            P+C++   LC N E CI     CDG++DC+DGSDE       FCRL
Sbjct: 3512 PMCSSTQFLCGNNEKCIPIWWKCDGQKDCSDGSDEPDLCPHRFCRL 3557

 Score = 41.6 bits (96), Expect = 0.005
 Identities = 26/75 (34%), Positives = 33/75 (44%), Gaps = 2/75 (2%)
 Frame = +2

Query: 944  RFTCRKGRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFC--R 1117
            R  C  G S  D ++     C +    C N  CI  +  CD   DC D SDED   C  R
Sbjct: 3577 RQDCADG-SDEDRVLCEHHRCESNEWQCANKRCIPQSWQCDSVNDCLDNSDEDTSHCASR 3635

Query: 1118 LCDPLSKRCETHNGQ 1162
             C P   +C  +NG+
Sbjct: 3636 TCRPGQFKC--NNGR 3648

 Score = 40.4 bits (93), Expect = 0.011
 Identities = 21/56 (37%), Positives = 25/56 (44%), Gaps = 1/56 (1%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQ-EFCRLCDPLSKRCETHNGQNP 1168
            C + S  C N  CI     CD   DC+DGSDE   +    C P   RC  H   +P
Sbjct: 1110 CPSTSFTCDNHVCIPKDWVCDTDNDCSDGSDEKNCQASGTCQPTQFRCPDHRCISP 1165

 Score = 40.4 bits (93), Expect = 0.011
 Identities = 21/58 (36%), Positives = 23/58 (39%), Gaps = 14/58 (24%)
 Frame = +2

Query: 1025 CRNGECINSAKFCDGKRDCADGSDEDQEFCRL--------------CDPLSKRCETHN 1156
            C NG CIN    CD   DC DGSDE    C                C P   RC+ +N
Sbjct: 2708 CLNGHCINQDWKCDNDNDCGDGSDELPTVCAFHTCRSTAFTCGNGRCVPYHYRCDYYN 2765

 Score = 40.0 bits (92), Expect = 0.015
 Identities = 21/49 (42%), Positives = 25/49 (51%), Gaps = 2/49 (4%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQ--EFCRLCDPLSKRC 1144
            C + S  C NG+C+ S   CDG  DC D SDE Q   F   C P +  C
Sbjct: 1025 CGSLSFPCNNGKCVPSFFRCDGVDDCHDNSDEHQCGVFNNTCSPSAFAC 1073

 Score = 39.7 bits (91), Expect = 0.019
 Identities = 16/33 (48%), Positives = 17/33 (51%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDED 1102
            C      C NG+CIN    CDG  DC D  DED
Sbjct: 222  CGGHQFTCSNGQCINQNWVCDGDDDCQDSGDED 254

 Score = 39.7 bits (91), Expect = 0.019
 Identities = 18/36 (50%), Positives = 19/36 (52%)
 Frame = +2

Query: 992  VDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDE 1099
            V   C+    LC NG CI  A  CDG  DC D SDE
Sbjct: 1268 VPKTCSPTHFLCDNGNCIYKAWICDGDNDCRDMSDE 1303

 Score = 39.3 bits (90), Expect = 0.025
 Identities = 16/32 (50%), Positives = 21/32 (65%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 1099
            C +G+  C NG CI ++  CDG RDC D +DE
Sbjct: 28   CGSGNFRCDNGYCIPASWRCDGTRDCLDDTDE 59

 Score = 39.3 bits (90), Expect = 0.025
 Identities = 15/32 (46%), Positives = 19/32 (59%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 1099
            C+AG   C NG C+  +  CD + DC D SDE
Sbjct: 2995 CSAGEFSCANGRCVRQSFRCDRRNDCGDYSDE 3026

 Score = 38.5 bits (88), Expect = 0.043
 Identities = 22/43 (51%), Positives = 25/43 (58%), Gaps = 8/43 (18%)
 Frame = +2

Query: 995  DPICTAGSRLCRNGE--------CINSAKFCDGKRDCADGSDE 1099
            +PI  A S  CR+ E        CI S  FCDG+ DCADGSDE
Sbjct: 2856 NPIYCA-SHTCRSNEFQCLSPQRCIPSYWFCDGEADCADGSDE 2897

 Score = 38.1 bits (87), Expect = 0.056
 Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
 Frame = +2

Query: 1004 CTAGSRLC-RNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETHNGQ 1162
            C +G  LC   G CI S+  CD  +DC+DG+DE Q  C      +++    NGQ
Sbjct: 67   CESGLFLCPAEGTCIPSSWVCDEDKDCSDGADEQQN-CAGTTCSAQQMTCSNGQ 119

 Score = 37.7 bits (86), Expect = 0.073
 Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 1/64 (1%)
 Frame = +2

Query: 995  DPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLC-DPLSKRCETHNGQNPT 1171
            +P C      C NG CI   + C+   DC+D SDE       C D    RC+ HN  +  
Sbjct: 3074 EPTCPLHQFRCDNGHCIEMGRVCNHVDDCSDNSDEKGCGINECLDSSISRCD-HNCTDTI 3132

Query: 1172 NNIY 1183
             + Y
Sbjct: 3133 TSFY 3136

 Score = 37.4 bits (85), Expect = 0.096
 Identities = 18/50 (36%), Positives = 22/50 (44%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETH 1153
            C  G   C NG CI  +  CD   DC D SDE  + C      +  C+ H
Sbjct: 3637 CRPGQFKCNNGRCIPQSWKCDVDNDCGDYSDEPIDECTTA---AYNCDNH 3683

 Score = 37.4 bits (85), Expect = 0.096
 Identities = 19/49 (38%), Positives = 21/49 (42%)
 Frame = +2

Query: 998  PICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRC 1144
            P   +G   C N  CI     CDG  DC D SDE+    R C     RC
Sbjct: 3720 PCHPSGDFRCANHHCIPLRWKCDGTDDCGDNSDEENCVpreCSESEFRC 3768

 Score = 37.0 bits (84), Expect = 0.13
 Identities = 15/31 (48%), Positives = 18/31 (58%)
 Frame = +2

Query: 1007 TAGSRLCRNGECINSAKFCDGKRDCADGSDE 1099
            T     C NG C N+++ CD K DC D SDE
Sbjct: 146  TCDQLTCANGACYNTSQRCDQKVDCRDSSDE 176

 Score = 37.0 bits (84), Expect = 0.13
 Identities = 16/46 (34%), Positives = 23/46 (50%), Gaps = 2/46 (4%)
 Frame = +2

Query: 1025 CRNGECINSAKFCDGKRDCADGSDEDQEFC--RLCDPLSKRCETHN 1156
            C NG CI  +  C+G  +C D    D++ C    C P   +C+T N
Sbjct: 2789 CSNGRCIPLSYVCNGINNCHDNDTSDEKNCPPHTCPPDFTKCQTTN 2834

 Score = 36.6 bits (83), Expect = 0.16
 Identities = 14/25 (56%), Positives = 17/25 (68%)
 Frame = +2

Query: 1025 CRNGECINSAKFCDGKRDCADGSDE 1099
            C +  CI+    CDG +DCADGSDE
Sbjct: 1157 CPDHRCISPLYVCDGDKDCADGSDE 1181

 Score = 36.6 bits (83), Expect = 0.16
 Identities = 15/32 (46%), Positives = 19/32 (59%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCSD 1295
            CDG DDCG+  DE  C    REC    ++C+D
Sbjct: 3741 CDGTDDCGDNSDEENCV--preCSESEFRCAD 3770

 Score = 36.2 bits (82), Expect = 0.21
 Identities = 17/33 (51%), Positives = 19/33 (57%), Gaps = 1/33 (3%)
 Frame = +2

Query: 1004 CTAGSRLCRNGE-CINSAKFCDGKRDCADGSDE 1099
            CT+    C +G  CINS   CDG  DC D SDE
Sbjct: 1188 CTSAQFKCADGSSCINSRYRCDGVYDCRDNSDE 1220

 Score = 36.2 bits (82), Expect = 0.21
 Identities = 16/47 (34%), Positives = 22/47 (46%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRC 1144
            C+     C + +CI S   CD + DC D SDE     + C P   +C
Sbjct: 3761 CSESEFRCADQQCIPSRWVCDQENDCGDNSDERDCEMKTCHPEHFQC 3807

 Score = 36.2 bits (82), Expect = 0.21
 Identities = 13/25 (52%), Positives = 16/25 (64%)
 Frame = +2

Query: 1025 CRNGECINSAKFCDGKRDCADGSDE 1099
            C +G C+  A  CDG+ DC D SDE
Sbjct: 3807 CTSGHCVPKALACDGRADCLDASDE 3831

 Score = 35.8 bits (81), Expect = 0.28
 Identities = 19/49 (38%), Positives = 22/49 (44%)
 Frame = +2

Query: 953  CRKGRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDE 1099
            CR     A+   L    C+     C +GECI  A  CD   DC D SDE
Sbjct: 170  CRDSSDEANCTTL----CSQKEFECGSGECILRAYVCDHDNDCEDNSDE 214

 Score = 35.8 bits (81), Expect = 0.28
 Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 5/55 (9%)
 Frame = +2

Query: 1004 CTAGSRLC-RNGECINSAKFCDGKRDCADGSDED----QEFCRLCDPLSKRCETH 1153
            C+  +  C R G+CI     CD + DC DGSDE           C   S  C+ H
Sbjct: 1066 CSPSAFACVRGGQCIPGQWHCDRQNDCLDGSDEQNCPTHATSSTCPSTSFTCDNH 1120

 Score = 35.8 bits (81), Expect = 0.28
 Identities = 14/34 (41%), Positives = 21/34 (61%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCSDGT 1301
            CDG+ DC +G DE+ C   V  C    ++C+DG+
Sbjct: 1169 CDGDKDCADGSDEAGC---VLNCTSAQFKCADGS 1199

 Score = 35.8 bits (81), Expect = 0.28
 Identities = 13/25 (52%), Positives = 16/25 (64%)
 Frame = +2

Query: 1040 CINSAKFCDGKRDCADGSDEDQEFC 1114
            C+  A  CDG  DC DGSDE+  +C
Sbjct: 2836 CVPRAFLCDGDNDCGDGSDENPIYC 2860

 Score = 35.8 bits (81), Expect = 0.28
 Identities = 15/34 (44%), Positives = 19/34 (55%), Gaps = 1/34 (2%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDE-SRCSGNVRECGGLTYQCSDG 1298
            CDGE DC +G DE   C  +V  C    +QC +G
Sbjct: 2885 CDGEADCADGSDEPDTCGHSVNTCRASQFQCDNG 2918

 Score = 35.4 bits (80), Expect = 0.36
 Identities = 15/32 (46%), Positives = 16/32 (50%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 1099
            CT     C NG CI+    CD   DC D SDE
Sbjct: 3930 CTDTEYKCSNGNCISQHYVCDNVNDCGDLSDE 3961

 Score = 33.5 bits (75), Expect = 1.4
 Identities = 14/33 (42%), Positives = 19/33 (57%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCSDG 1298
            CD ++DC +  DE  C  N   CGG  + CS+G
Sbjct: 202  CDHDNDCEDNSDERNC--NYDTCGGHQFTCSNG 232

 Score = 33.5 bits (75), Expect = 1.4
 Identities = 21/72 (29%), Positives = 28/72 (38%), Gaps = 2/72 (2%)
 Frame = +2

Query: 947  FTCRKGRSSADVIVLVDPICTAGSRLCR-NGECINSAKFCDGKRDCADGSDEDQEFC-RL 1120
            + CR     A        +C      C+ +G CI +   CDG  DC  GSDE      + 
Sbjct: 1212 YDCRDNSDEAGCPTRPPGMCHPDEFQCQGDGTCIPNTWECDGHPDCIHGSDEHTGCVPKT 1271

Query: 1121 CDPLSKRCETHN 1156
            C P    C+  N
Sbjct: 1272 CSPTHFLCDNGN 1283

 Score = 33.5 bits (75), Expect = 1.4
 Identities = 20/45 (44%), Positives = 22/45 (48%), Gaps = 4/45 (8%)
 Frame = +3

Query: 1176 TFIKHTGACDGEDDCGNGFDESRCSGNVREC----GGLTYQCSDG 1298
            T I  +  CDG  DC NG DES    N   C    GG T+QC  G
Sbjct: 1325 TCINLSALCDGVFDCPNGTDESPLC-NQDSCSHFNGGCTHQCMQG 1368

 Score = 32.3 bits (72), Expect = 3.1
 Identities = 12/24 (50%), Positives = 16/24 (66%)
 Frame = +2

Query: 1031 NGECINSAKFCDGKRDCADGSDED 1102
            +G CI+  K CDG  DC +G DE+
Sbjct: 275  SGRCISIDKVCDGVPDCPEGDDEN 298

 Score = 32.3 bits (72), Expect = 3.1
 Identities = 15/41 (36%), Positives = 19/41 (46%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCD 1126
            C + +  C NG C+     CD   DC D SDE     R C+
Sbjct: 2742 CRSTAFTCGNGRCVPYHYRCDYYNDCGDNSDEAGCLFRNCN 2782

 Score = 31.2 bits (69), Expect = 6.9
 Identities = 12/30 (40%), Positives = 17/30 (56%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQC 1289
            CDG++DCG+G DE+        C    +QC
Sbjct: 2843 CDGDNDCGDGSDENPIYCASHTCRSNEFQC 2872

 Score = 31.2 bits (69), Expect = 6.9
 Identities = 13/33 (39%), Positives = 19/33 (57%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCSDG 1298
            CD E+DCG+  DE  C   ++ C    +QC+ G
Sbjct: 3780 CDQENDCGDNSDERDC--EMKTCHPEHFQCTSG 3810

 Score = 31.2 bits (69), Expect = 6.9
 Identities = 15/36 (41%), Positives = 20/36 (55%), Gaps = 3/36 (8%)
 Frame = +3

Query: 1200 CDGEDDCGNGFD--ESRC-SGNVRECGGLTYQCSDG 1298
            C+G DDCG+G D  E  C     + C    Y+CS+G
Sbjct: 3905 CNGVDDCGDGSDEKEEHCRKPTHKPCTDTEYKCSNG 3940

 Score = 30.8 bits (68), Expect = 9.0
 Identities = 17/40 (42%), Positives = 21/40 (52%)
 Frame = +2

Query: 1040 CINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETHNG 1159
            CIN +  CDG  DC +G+DE      LC+  S  C   NG
Sbjct: 1326 CINLSALCDGVFDCPNGTDESP----LCNQDS--CSHFNG 1359

>sp|Q92673|SORL_HUMAN Sortilin-related receptor precursor (Sorting protein-related receptor
            containing LDLR class A repeats) (SorLA) (SorLA-1)
            (Low-density lipoprotein receptor relative with 11
            ligand-binding repeats) (LDLR relative with 11
            ligand-binding repeats) (LR11)
          Length = 2214

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 25/59 (42%), Positives = 27/59 (45%), Gaps = 11/59 (18%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCR-----------LCDPLSKRCE 1147
            C A +  CRNG CI     CDG  DC DGSDED   C             C P SK C+
Sbjct: 1199 CEASNFQCRNGHCIPQRWACDGDTDCQDGSDEDPVNCEKKCNGFRCPNGTCIPSSKHCD 1257

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 21/36 (58%), Positives = 24/36 (66%)
 Frame = +2

Query: 1025 CRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPL 1132
            C NG CI S+K CDG RDC+DGSDE       C+PL
Sbjct: 1244 CPNGTCIPSSKHCDGLRDCSDGSDEQH-----CEPL 1274

 Score = 41.6 bits (96), Expect = 0.005
 Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 16/79 (20%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDE----------DQEF-CR---LCDPLSKR 1141
            C      C NG CINS  +CD   DC D SDE          D +F C+    C PLS +
Sbjct: 1078 CLRNQYRCSNGNCINSIWWCDFDNDCGDMSDERNCPTTICDLDTQFRCQESGTCIPLSYK 1137

Query: 1142 CETHN--GQNPTNNIYQAH 1192
            C+  +  G N   +  + H
Sbjct: 1138 CDLEDDCGDNSDESHCEMH 1156

 Score = 40.8 bits (94), Expect = 0.009
 Identities = 21/64 (32%), Positives = 26/64 (40%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETHNGQNPTNNIY 1183
            C +    C +G CI S+  CDG  DC D SDE       C  +   CE  N Q    +  
Sbjct: 1158 CRSDEYNCSSGMCIRSSWVCDGDNDCRDWSDEAN-----CTAIYHTCEASNFQCRNGHCI 1212

Query: 1184 QAHW 1195
               W
Sbjct: 1213 PQRW 1216

 Score = 40.4 bits (93), Expect = 0.011
 Identities = 16/33 (48%), Positives = 19/33 (57%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDED 1102
            C      C +G C+     CDG RDCADGSDE+
Sbjct: 1419 CLPNYYRCSSGTCVMDTWVCDGYRDCADGSDEE 1451

 Score = 38.1 bits (87), Expect = 0.056
 Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 1/45 (2%)
 Frame = +3

Query: 1167 QPITFIKHTGACDGEDDCGNGFDESRC-SGNVRECGGLTYQCSDG 1298
            QP T I +   CDG  DC +G DE+ C + +   C    +QC DG
Sbjct: 1480 QPKTCIPNWKRCDGHQDCQDGRDEANCPTHSTLTCMSREFQCEDG 1524

 Score = 37.7 bits (86), Expect = 0.073
 Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 11/62 (17%)
 Frame = +2

Query: 995  DPICTAGSR-LCRNGE-CINSAKFCDGKRDCADGSDE---------DQEFCRLCDPLSKR 1141
            +P+CT     +C+N + C+  +  CDG   C DGSDE         D EF ++CD    +
Sbjct: 1272 EPLCTHFMDFVCKNRQQCLFHSMVCDGIIQCRDGSDEDAAFAGCSQDPEFHKVCDEFGFQ 1331

Query: 1142 CE 1147
            C+
Sbjct: 1332 CQ 1333

 Score = 37.0 bits (84), Expect = 0.13
 Identities = 16/33 (48%), Positives = 19/33 (57%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCSDG 1298
            CD EDDCG+  DES C   + +C    Y CS G
Sbjct: 1138 CDLEDDCGDNSDESHC--EMHQCRSDEYNCSSG 1168

 Score = 36.6 bits (83), Expect = 0.16
 Identities = 13/39 (33%), Positives = 22/39 (56%)
 Frame = +3

Query: 1182 IKHTGACDGEDDCGNGFDESRCSGNVRECGGLTYQCSDG 1298
            I+ +  CDG++DC +  DE+ C+     C    +QC +G
Sbjct: 1171 IRSSWVCDGDNDCRDWSDEANCTAIYHTCEASNFQCRNG 1209

 Score = 35.4 bits (80), Expect = 0.36
 Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
 Frame = +2

Query: 953  CRKGRSSADVIVLVDPICTAGSRLCRNGE-CINSAKFCDGKRDCADGSDE 1099
            C+ GR  A+        C +    C +GE CI  ++ CDG  DC+D SDE
Sbjct: 1497 CQDGRDEANCPTHSTLTCMSREFQCEDGEACIVLSERCDGFLDCSDESDE 1546

 Score = 34.7 bits (78), Expect = 0.62
 Identities = 15/33 (45%), Positives = 18/33 (54%)
 Frame = +2

Query: 1001 ICTAGSRLCRNGECINSAKFCDGKRDCADGSDE 1099
            +C      C+NG CI+    CDG  DC D SDE
Sbjct: 1324 VCDEFGFQCQNGVCISLIWKCDGMDDCGDYSDE 1356

 Score = 33.1 bits (74), Expect = 1.8
 Identities = 13/25 (52%), Positives = 15/25 (60%)
 Frame = +2

Query: 1025 CRNGECINSAKFCDGKRDCADGSDE 1099
            C NG CI +   CD + DC D SDE
Sbjct: 1376 CENGHCIPNRWKCDRENDCGDWSDE 1400

 Score = 30.8 bits (68), Expect = 9.0
 Identities = 12/20 (60%), Positives = 14/20 (70%)
 Frame = +2

Query: 1040 CINSAKFCDGKRDCADGSDE 1099
            CI + K CDG +DC DG DE
Sbjct: 1484 CIPNWKRCDGHQDCQDGRDE 1503

>sp|Q04833|LRP_CAEEL Low-density lipoprotein receptor-related protein precursor (LRP)
          Length = 4753

 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 25/60 (41%), Positives = 27/60 (45%), Gaps = 2/60 (3%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCR--LCDPLSKRCETHNGQNPTNN 1177
            C A    C NG CI     CDG  DC DG+DED+E C    C  L  RC       P  N
Sbjct: 1187 CAANQFSCANGRCIPIYWLCDGDNDCYDGTDEDKERCPPVQCSALQFRCANGRQCVPLRN 1246

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 23/64 (35%), Positives = 27/64 (42%)
 Frame = +2

Query: 953  CRKGRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPL 1132
            CR G       +    IC  G   C N  C    + CDG  DC D SDE Q   + CDP 
Sbjct: 3654 CRDGSDEPGESICGQRICPVGEFQCTNHNCTRPFQICDGNDDCGDSSDE-QNCDKACDPW 3712

Query: 1133 SKRC 1144
              +C
Sbjct: 3713 MFKC 3716

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 19/48 (39%), Positives = 27/48 (56%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCE 1147
            C+     C +G+CI  +K CDG   C+DG DE Q   R C P  ++C+
Sbjct: 3878 CSESEFRCNDGKCIPGSKVCDGTIQCSDGLDESQCTLRRCLPGHRQCD 3925

 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 22/51 (43%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
 Frame = +2

Query: 1004 CTAGSRLCRN-GECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETH 1153
            C  G   C   G CI+  K CDG +DCADG+DE Q    LC  L  +   H
Sbjct: 262  CPPGKWNCPGTGHCIDQLKLCDGSKDCADGADEQQCSQNLCPSLGCQAGCH 312

 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 36/135 (26%), Positives = 51/135 (37%), Gaps = 27/135 (20%)
 Frame = +2

Query: 830  FMANGGRASDSQRTTVEKLEAGKVQLTYRAVTTNDNGTRFTCRKGR---------SSADV 982
            FM N       Q+   EK+E             + N T+F C+ GR            D 
Sbjct: 1032 FMINKENNHSCQKDPAEKIEQ----------LCSSNSTQFQCKNGRCIPKEWKCDGENDC 1081

Query: 983  IVLVDPI------------CTAGSRLCRNGE-CINSAKFCDGKRDCADGSDEDQEFCR-- 1117
            +   D I            C   +  CRN + CI +   CDG  DC D SDED ++C+  
Sbjct: 1082 LDESDEIDEKGDKCFHETECAENTIKCRNTKKCIPAQYGCDGDNDCGDYSDEDVKYCKDG 1141

Query: 1118 ---LCDPLSKRCETH 1153
               +C     +C+ H
Sbjct: 1142 QKPVCAAKKFQCDNH 1156

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 21/55 (38%), Positives = 26/55 (47%)
 Frame = +2

Query: 944  RFTCRKGRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQE 1108
            +F C  GR            C++    C NG CI +   CDG+ DC DGSDE  E
Sbjct: 1304 KFGCTSGRQ-----------CSSDQFKCGNGRCILNNWLCDGENDCGDGSDESSE 1347

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 31/88 (35%), Positives = 40/88 (45%), Gaps = 11/88 (12%)
 Frame = +2

Query: 938  GTRFTCRKGRSSADVIVLV------DPICTAGSRLCR--NGECINSAKFCDGKRDCADGS 1093
            G  +TC    S  D  VL+      +P CT     C   + +CI    +CDG+ DC DGS
Sbjct: 3603 GNGYTC----SCPDQFVLLSDQKTCEPNCTERQFACGGDDAKCIPKLWYCDGEPDCRDGS 3658

Query: 1094 DEDQE-FC--RLCDPLSKRCETHNGQNP 1168
            DE  E  C  R+C     +C  HN   P
Sbjct: 3659 DEPGESICGQRICPVGEFQCTNHNCTRP 3686

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 21/51 (41%), Positives = 29/51 (56%), Gaps = 2/51 (3%)
 Frame = +2

Query: 1004 CTAGSRLCRNG-ECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSK-RCET 1150
            C  G   C +   CI +  FC+G+ DC D SDED++ C  CD + + RC T
Sbjct: 3793 CKKGWTRCSSSYRCIPNWAFCNGQDDCRDNSDEDKQRCPTCDDVGEFRCAT 3843

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 22/59 (37%), Positives = 25/59 (42%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETHNGQNPTNNI 1180
            C  G+  C NG CIN  K CDG  DC D    D+     C  L   C     + P  NI
Sbjct: 2874 CAEGTFPCSNGHCINQTKVCDGHNDCHDEQVSDESLA-TCPGLPIDCRGVKVRCPNTNI 2931

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 25/70 (35%), Positives = 29/70 (41%), Gaps = 2/70 (2%)
 Frame = +2

Query: 950  TCRKGRS-SADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFC-RLC 1123
            TC  G   S ++       C  G   C N  CI+S   CDG  DC DGSDE        C
Sbjct: 3081 TCAGGEDESTELCKTEKKECNKGEFRCSNQHCIHSTWECDGDNDCLDGSDEHANCTYSSC 3140

Query: 1124 DPLSKRCETH 1153
             P   +C  H
Sbjct: 3141 QPDFFQCANH 3150

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 18/39 (46%), Positives = 19/39 (48%)
 Frame = +2

Query: 998  PICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFC 1114
            P+C A    C N  CI     CD   DC DGSDE  E C
Sbjct: 1144 PVCAAKKFQCDNHRCIPEQWKCDSDNDCGDGSDEKLEMC 1182

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 26/77 (33%), Positives = 32/77 (41%), Gaps = 8/77 (10%)
 Frame = +2

Query: 944  RFTCRKGRSSADVIVLVDPICTAGSR-------LCRNGECINSAKFCDGKRDCADGSDED 1102
            RFTC       D     D +C +  R        C N +CI  A  CD   DC DGSDE 
Sbjct: 3726 RFTCDGDDDCGDRSDEADTLCMSAERNCTAEEFRCNNNKCIAKAWRCDNDDDCGDGSDET 3785

Query: 1103 QEFCRL-CDPLSKRCET 1150
             E  ++ C     RC +
Sbjct: 3786 PECAQIECKKGWTRCSS 3802

 Score = 42.0 bits (97), Expect = 0.004
 Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 3/50 (6%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDE---DQEFCRLCDPLSKRC 1144
            C  G R C +G CI   K+CD K+DC + +DE   +    R C P    C
Sbjct: 3917 CLPGHRQCDDGTCIAEHKWCDRKKDCPNAADELHCEDVSRRTCSPFEFEC 3966

 Score = 41.2 bits (95), Expect = 0.007
 Identities = 17/32 (53%), Positives = 20/32 (62%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 1099
            C+ G   C +GECI+ AK CD   DC D SDE
Sbjct: 3187 CSNGQFQCTSGECIDDAKVCDRNFDCTDRSDE 3218

 Score = 40.4 bits (93), Expect = 0.011
 Identities = 24/64 (37%), Positives = 30/64 (46%), Gaps = 16/64 (25%)
 Frame = +2

Query: 1004 CTAGSRLCRNG-ECINSAKFCDGKRDCADGSDEDQ-----EFCR----------LCDPLS 1135
            C+A    C NG +C+     CDG+ DC DGSDED      E C           LC P S
Sbjct: 1228 CSALQFRCANGRQCVPLRNHCDGQSDCEDGSDEDSCAVTAESCTPDQFKCVSSGLCIPAS 1287

Query: 1136 KRCE 1147
             +C+
Sbjct: 1288 WKCD 1291

 Score = 40.4 bits (93), Expect = 0.011
 Identities = 21/43 (48%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
 Frame = +2

Query: 1025 CRNGECINSAKFCDGKRDCADGSDEDQEFCR--LCD-PLSKRC 1144
            C N  CI     CDG  DC D SDE    CR   CD PL  RC
Sbjct: 3966 CANSVCIPRKFMCDGDNDCGDNSDETSSECRSAQCDPPLRFRC 4008

 Score = 40.0 bits (92), Expect = 0.015
 Identities = 15/32 (46%), Positives = 19/32 (59%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 1099
            C++    C NG+C+N    CD K DC D SDE
Sbjct: 4049 CSSDQFKCANGKCVNGTVACDRKDDCGDASDE 4080

 Score = 39.7 bits (91), Expect = 0.019
 Identities = 18/52 (34%), Positives = 26/52 (50%)
 Frame = +2

Query: 1040 CINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETHNGQNPTNNIYQAHW 1195
            CI  A  CDG  DC D +DE+Q FC     ++++C  H  + P+       W
Sbjct: 2932 CIQPADLCDGYDDCGDKADENQLFC-----MNQQCAQHYVRCPSGRCIPETW 2978

 Score = 38.9 bits (89), Expect = 0.033
 Identities = 17/51 (33%), Positives = 25/51 (49%)
 Frame = +2

Query: 1001 ICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETH 1153
            +C      C +G+CI +   CDG  DC+DG DE       C     +C+T+
Sbjct: 52   VCNENDFRCNDGKCIRTEWKCDGSGDCSDGEDEKDCPHPGCKSDQWQCDTY 102

 Score = 38.9 bits (89), Expect = 0.033
 Identities = 15/30 (50%), Positives = 18/30 (60%)
 Frame = +2

Query: 1025 CRNGECINSAKFCDGKRDCADGSDEDQEFC 1114
            C +G CI     CD K DCAD SDE+  +C
Sbjct: 2800 CGDGSCILLGATCDSKPDCADASDENPNYC 2829

 Score = 38.9 bits (89), Expect = 0.033
 Identities = 17/32 (53%), Positives = 19/32 (59%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 1099
            C     LC N  CI+SAK C+   DC DGSDE
Sbjct: 2834 CPEDYNLCTNRRCIDSAKKCNHIDDCGDGSDE 2865

 Score = 38.5 bits (88), Expect = 0.043
 Identities = 28/79 (35%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
 Frame = +2

Query: 953  CRKGRSSADVIVLVDPICTAGSRLC-RNGECINSAKFCDGKRDCADGSDEDQEFC---RL 1120
            C  G S  D   +    CT     C  +G CI ++  CDG++DC DGSDE +  C   R 
Sbjct: 1254 CEDG-SDEDSCAVTAESCTPDQFKCVSSGLCIPASWKCDGQQDCDDGSDEPKFGCTSGRQ 1312

Query: 1121 CDPLSKRCETHNGQNPTNN 1177
            C     +C   NG+   NN
Sbjct: 1313 CSSDQFKC--GNGRCILNN 1329

 Score = 37.7 bits (86), Expect = 0.073
 Identities = 15/25 (60%), Positives = 18/25 (72%)
 Frame = +2

Query: 1025 CRNGECINSAKFCDGKRDCADGSDE 1099
            C N +CI+ A  CDG+ DC DGSDE
Sbjct: 3014 CDNLKCISRAFICDGEDDCGDGSDE 3038

 Score = 37.7 bits (86), Expect = 0.073
 Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
 Frame = +2

Query: 1004 CTAGSRLCR-NGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRCETHNGQNPTNNI 1180
            CT+ ++L +   ECI  A  CDG   CA G DE  E C+     +++ E + G+   +N 
Sbjct: 3056 CTSNAKLAQPKYECIPRAWLCDGDVTCAGGEDESTELCK-----TEKKECNKGEFRCSNQ 3110

Query: 1181 YQAH 1192
            +  H
Sbjct: 3111 HCIH 3114

 Score = 37.7 bits (86), Expect = 0.073
 Identities = 15/35 (42%), Positives = 21/35 (60%), Gaps = 2/35 (5%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDE--SRCSGNVRECGGLTYQCSDG 1298
            CD E+DCG+  DE  + C G  R C    ++C+DG
Sbjct: 3854 CDTENDCGDNSDELDASCGGTTRPCSESEFRCNDG 3888

 Score = 36.2 bits (82), Expect = 0.21
 Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 13/53 (24%)
 Frame = +2

Query: 1037 ECINSAKFCDGKRDCADGSDEDQ--EF--C---------RLCDPLSKRCETHN 1156
            +CI  +  CDG +DCADGSDE    EF  C         + C P   RC+ ++
Sbjct: 194  QCIQKSWVCDGSKDCADGSDEPDTCEFKKCTANEFQCKNKRCQPRKFRCDYYD 246

 Score = 36.2 bits (82), Expect = 0.21
 Identities = 17/36 (47%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDE-SRCSGNVRECGGLTYQCSDGTK 1304
            CDGEDDCG+G DE SR     R C    + C+   K
Sbjct: 3026 CDGEDDCGDGSDEHSRHGCGNRTCTDQEFHCTSNAK 3061

 Score = 35.0 bits (79), Expect = 0.48
 Identities = 14/30 (46%), Positives = 16/30 (53%)
 Frame = +2

Query: 1025 CRNGECINSAKFCDGKRDCADGSDEDQEFC 1114
            C +G CI     CDG  DC+DG DE    C
Sbjct: 2968 CPSGRCIPETWQCDGDNDCSDGWDETHTNC 2997

 Score = 35.0 bits (79), Expect = 0.48
 Identities = 13/25 (52%), Positives = 17/25 (68%)
 Frame = +2

Query: 1025 CRNGECINSAKFCDGKRDCADGSDE 1099
            C N +C+ ++  CDG  DC DGSDE
Sbjct: 3147 CANHKCVPNSWKCDGNDDCEDGSDE 3171

 Score = 34.7 bits (78), Expect = 0.62
 Identities = 18/47 (38%), Positives = 20/47 (42%)
 Frame = +2

Query: 1004 CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPLSKRC 1144
            CTA    C+N  C      CD   DC D SDED+     C P    C
Sbjct: 223  CTANEFQCKNKRCQPRKFRCDYYDDCGDNSDEDECGEYRCPPGKWNC 269

 Score = 34.7 bits (78), Expect = 0.62
 Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 6/45 (13%)
 Frame = +3

Query: 1182 IKHTGACDGEDDCGNGFDESRCSGN------VRECGGLTYQCSDG 1298
            + ++  CDG DDC +G DE  C  N        +C    +QC+ G
Sbjct: 3153 VPNSWKCDGNDDCEDGSDEKDCPKNSASAQKASKCSNGQFQCTSG 3197

 Score = 34.7 bits (78), Expect = 0.62
 Identities = 16/34 (47%), Positives = 20/34 (58%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCSDGT 1301
            CDG   C +G DES+C+  +R C     QC DGT
Sbjct: 3897 CDGTIQCSDGLDESQCT--LRRCLPGHRQCDDGT 3928

 Score = 33.5 bits (75), Expect = 1.4
 Identities = 15/28 (53%), Positives = 19/28 (67%), Gaps = 5/28 (17%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDES-----RCSGNVREC 1268
            CDGE+DCG+G DES     + S N R+C
Sbjct: 1332 CDGENDCGDGSDESSERGCKTSMNARKC 1359

 Score = 33.1 bits (74), Expect = 1.8
 Identities = 15/33 (45%), Positives = 20/33 (60%), Gaps = 1/33 (3%)
 Frame = +2

Query: 1022 LCRNG-ECINSAKFCDGKRDCADGSDEDQEFCR 1117
            +C +G +C + +K CDGK DC D SDE     R
Sbjct: 145  MCADGRQCFDVSKKCDGKYDCRDLSDEKDSCSR 177

 Score = 33.1 bits (74), Expect = 1.8
 Identities = 12/33 (36%), Positives = 21/33 (63%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCSDG 1298
            CDG++DC +G DE +      +C  L ++C++G
Sbjct: 1206 CDGDNDCYDGTDEDKERCPPVQCSALQFRCANG 1238

 Score = 33.1 bits (74), Expect = 1.8
 Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 8/46 (17%)
 Frame = +3

Query: 1182 IKHTGACDGEDDCGNGFDESRCS--GNVREC------GGLTYQCSD 1295
            +  T ACD +DDCG+  DE  CS  G    C      GG  + C+D
Sbjct: 4062 VNGTVACDRKDDCGDASDEIGCSKHGGKTSCEAFGNNGGCKHICTD 4107

 Score = 32.7 bits (73), Expect = 2.4
 Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 4/46 (8%)
 Frame = +2

Query: 1019 RLCRNGECINSAKFCDGKRDCADGSDEDQEFC----RLCDPLSKRC 1144
            R   +G+CI     CD + DC D SDE    C    R C     RC
Sbjct: 3840 RCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRPCSESEFRC 3885

 Score = 32.0 bits (71), Expect = 4.0
 Identities = 11/30 (36%), Positives = 16/30 (53%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQC 1289
            CDG+ DC +G DE  C+     C    ++C
Sbjct: 1248 CDGQSDCEDGSDEDSCAVTAESCTPDQFKC 1277

 Score = 32.0 bits (71), Expect = 4.0
 Identities = 15/33 (45%), Positives = 19/33 (57%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCSDG 1298
            C+  DDCG+G DE  C   V  C   T+ CS+G
Sbjct: 2853 CNHIDDCGDGSDELDCPSAV-ACAEGTFPCSNG 2884

 Score = 32.0 bits (71), Expect = 4.0
 Identities = 12/31 (38%), Positives = 17/31 (54%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGLTYQCS 1292
            CDG DDCG+  DE  C    + C    ++C+
Sbjct: 3690 CDGNDDCGDSSDEQNCD---KACDPWMFKCA 3717

 Score = 32.0 bits (71), Expect = 4.0
 Identities = 17/44 (38%), Positives = 18/44 (40%), Gaps = 4/44 (9%)
 Frame = +2

Query: 1034 GECINSAKFCDGKRDCADGSDEDQEFC----RLCDPLSKRCETH 1153
            G CI     CDG  DC D SDE    C    R C     RC  +
Sbjct: 3720 GRCIPRRFTCDGDDDCGDRSDEADTLCMSAERNCTAEEFRCNNN 3763

 Score = 32.0 bits (71), Expect = 4.0
 Identities = 13/34 (38%), Positives = 20/34 (58%), Gaps = 2/34 (5%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDE--SRCSGNVRECGGLTYQCSD 1295
            CDG+DDCG+  DE  + C    R C    ++C++
Sbjct: 3729 CDGDDDCGDRSDEADTLCMSAERNCTAEEFRCNN 3762

 Score = 31.6 bits (70), Expect = 5.3
 Identities = 11/20 (55%), Positives = 14/20 (70%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNV 1259
            CDG  DC +G DE +CS N+
Sbjct: 282  CDGSKDCADGADEQQCSQNL 301

 Score = 31.6 bits (70), Expect = 5.3
 Identities = 13/35 (37%), Positives = 21/35 (60%), Gaps = 2/35 (5%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESR--CSGNVRECGGLTYQCSDG 1298
            CDG+ DC +G DE +  C+   R+C    ++C +G
Sbjct: 1290 CDGQQDCDDGSDEPKFGCTSG-RQCSSDQFKCGNG 1323

 Score = 30.8 bits (68), Expect = 9.0
 Identities = 12/34 (35%), Positives = 17/34 (50%), Gaps = 1/34 (2%)
 Frame = +3

Query: 1200 CDGEDDCGNGFDESRCSGNVRECGGL-TYQCSDG 1298
            CD   DC +G DE  C  +  +C     + C+DG
Sbjct: 116  CDNITDCADGSDEKDCPASTVDCSSQNVFMCADG 149

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 152,573,131
Number of Sequences: 369166
Number of extensions: 3265410
Number of successful extensions: 10681
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 8519
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10590
length of database: 68,354,980
effective HSP length: 114
effective length of database: 47,295,190
effective search space used: 15134460800
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

1. Dr_sW_021_M21
2. Dr_sW_009_A05
3. Dr_sW_007_L08