Planarian EST Database


Dr_sW_009_A05

BLASTX 2.2.12 [Aug-07-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Dr_sW_009_A05
         (848 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q05793|PGBM_MOUSE  Basement membrane-specific heparan sul...    54   4e-07
sp|P98163|YL_DROME  Putative vitellogenin receptor precursor...    51   5e-06
sp|Q06561|UNC52_CAEEL  Basement membrane proteoglycan precur...    51   5e-06
sp|P98160|PGBM_HUMAN  Basement membrane-specific heparan sul...    49   1e-05
sp|Q9NZR2|LRP1B_HUMAN  Low-density lipoprotein receptor-rela...    49   2e-05
sp|Q9JI18|LRP1B_MOUSE  Low-density lipoprotein receptor-rela...    48   3e-05
sp|Q98930|SORL_CHICK  Sortilin-related receptor (Sorting pro...    48   4e-05
sp|Q92673|SORL_HUMAN  Sortilin-related receptor precursor (S...    47   5e-05
sp|Q95209|SORL_RABIT  Sortilin-related receptor precursor (S...    47   9e-05
sp|P35952|LDLR_RAT  Low-density lipoprotein receptor precurs...    46   1e-04
>sp|Q05793|PGBM_MOUSE Basement membrane-specific heparan sulfate proteoglycan core protein
            precursor (HSPG) (Perlecan) (PLC)
          Length = 3707

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 43/162 (26%), Positives = 68/162 (41%), Gaps = 4/162 (2%)
 Frame = +1

Query: 28   IMILQNIQQMNEGKYECKVKGETKEAYI---IVMAKSRTIEVNPNEETRRVGDGRPVEFH 198
            ++ +QN+ Q  +G Y C+  G   +A     +++    ++ +N       V  G  VEF 
Sbjct: 2771 VLRIQNLDQNCQGTYVCQAHGPWGQAQATAQLIVQALPSVLINVRTSVHSVVVGHSVEFE 2830

Query: 199  CRIGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDDPTADETSFIILQQAELSDAGTYI 378
            C   G       V W   SK  G + P                + I +   EL+DAG Y 
Sbjct: 2831 CLALG--DPKPQVTW---SKVGGHLRP----------GIVQSGTIIRIAHVELADAGQYR 2875

Query: 379  CTEPDTRDTARS-ILNVISDLRIVVTPPIIKLRAGQTATFQC 501
            C   +   T +S +L ++  L  + TPP I++ AG  A F C
Sbjct: 2876 CAATNAAGTTQSHVLLLVQALPQISTPPEIRVPAGSAAVFPC 2917

 Score = 37.7 bits (86), Expect = 0.041
 Identities = 15/32 (46%), Positives = 17/32 (53%)
 Frame = +1

Query: 718 CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
           C      C +G CI     CDG+ DC DGSDE
Sbjct: 285 CGPQEASCHSGHCIPRDYLCDGQEDCRDGSDE 316

 Score = 37.4 bits (85), Expect = 0.053
 Identities = 31/122 (25%), Positives = 55/122 (45%), Gaps = 2/122 (1%)
 Frame = +1

Query: 25   SIMILQNIQQMNEGKYECKVKGE--TKEAYIIVMAKSRTIEVNPNEETRRVGDGRPVEFH 198
            +I+ + +++  + G+Y C       T +++++++ ++      P E   RV  G    F 
Sbjct: 2859 TIIRIAHVELADAGQYRCAATNAAGTTQSHVLLLVQALPQISTPPEI--RVPAGSAAVFP 2916

Query: 199  CRIGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDDPTADETSFIILQQAELSDAGTYI 378
            C   GY T    + W   SK  G + P +SR          E + ++L      DAGTY+
Sbjct: 2917 CMASGYPTPA--ITW---SKVDGDLPP-DSRL---------ENNMLMLPSVRPEDAGTYV 2961

Query: 379  CT 384
            CT
Sbjct: 2962 CT 2963

 Score = 37.0 bits (84), Expect = 0.069
 Identities = 40/166 (24%), Positives = 70/166 (42%), Gaps = 13/166 (7%)
 Frame = +1

Query: 43   NIQQMNEGKYECKVKG-----ETKEAYIIVMAKSRTIEVNPNEE-TRRVGDGRPVEFHCR 204
            ++Q  + G Y C  +       ++   ++  A S+ I V   E+ ++ V  G  V F C 
Sbjct: 1734 SVQPSDAGVYICTCRNLIHTSNSRAELLVAEAPSKPIMVTVEEQRSQSVRPGADVTFICT 1793

Query: 205  IGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDDPTADETSFIILQQAELSDAGTYICT 384
                ++    +VWT +         L SR         D    + ++  + SDAGTY+CT
Sbjct: 1794 AKS-KSPAYTLVWTRLHNGK-----LPSR-------AMDFNGILTIRNVQPSDAGTYVCT 1840

Query: 385  EPD--TRDTARSILNV-ISDLRIV----VTPPIIKLRAGQTATFQC 501
              +    D   + L+V +S         + PP + ++ GQ A F+C
Sbjct: 1841 GSNMFAMDQGTATLHVQVSGTSTAPVASIHPPQLTVQPGQQAEFRC 1886

 Score = 36.6 bits (83), Expect = 0.090
 Identities = 46/180 (25%), Positives = 73/180 (40%), Gaps = 20/180 (11%)
 Frame = +1

Query: 37   LQNIQQMNEGKYECKVKGE--TKEAYIIVMAKSRTIEVNPNEETRRVGDGRPVEFHCRIG 210
            L  +   + G+Y C+V G   T EA ++V     TIE +        G  +PV       
Sbjct: 2202 LNRVSPADSGEYSCQVTGSSGTLEASVLV-----TIEASEPSPIPAPGLAQPVYIESS-S 2255

Query: 211  GYRTKNR--DVVWTFMSKETGQITPLESRWSR--SDDPTADET--SFIILQQAELSDAGT 372
             + T+ +  D+      +   Q+T     W +  S  P   +T  S + L Q   +D+G 
Sbjct: 2256 SHLTEGQTVDLKCVVPGQAHAQVT-----WHKRGSSLPARHQTHGSLLRLYQLSPADSGE 2310

Query: 373  YICT---------EPDTRDTARSILNVISDLR---IVVTPPIIKLRAGQTATFQCYVLNG 516
            Y+C          E   + T  S  N    LR   I + PP   ++ GQ A+F+C +  G
Sbjct: 2311 YVCQVAGSSHPEHEASFKLTVPSSQNSSFRLRSPVISIEPPSSTVQQGQDASFKCLIHEG 2370

 Score = 35.4 bits (80), Expect = 0.20
 Identities = 29/88 (32%), Positives = 40/88 (45%), Gaps = 17/88 (19%)
 Frame = +1

Query: 289  RWSRSDDPTADE-------TSFIILQQAEL--SDAGTYICTEPDTRDTARSILNVISDLR 441
            RW+R   P   E        S  +L+ A +  SDAGTY+C   +   TA+  + +I D  
Sbjct: 2467 RWTRLGIPVKLEPRMFGLMNSHAMLKIASVKPSDAGTYVCQAQNALGTAQKQVELIVDTG 2526

Query: 442  IVV--TPPI------IKLRAGQTATFQC 501
             V   TP +      + L AG TAT  C
Sbjct: 2527 TVAPGTPQVQVEESELTLEAGHTATLHC 2554

 Score = 33.5 bits (75), Expect = 0.76
 Identities = 18/49 (36%), Positives = 21/49 (42%)
 Frame = +1

Query: 667 CRKGRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
           CR G  S ++     P C      C NG C      CDG  DC D +DE
Sbjct: 310 CRDG--SDELGCASPPPCEPNEFACENGHCALKLWRCDGDFDCEDRTDE 356

 Score = 30.8 bits (68), Expect = 5.0
 Identities = 29/143 (20%), Positives = 59/143 (41%), Gaps = 5/143 (3%)
 Frame = +1

Query: 13   RLYVSIMILQNIQQMNEGKYECKVKGETKEAYIIVMAKSR-----TIEVNPNEETRRVGD 177
            +++  I+ L  I+  ++G+Y C+      +     M +        ++V+P  E  +V +
Sbjct: 1911 QIHNGILRLPAIEPSDQGQYLCRALSSAGQHVARAMLQVHGGSGPRVQVSP--ERTQVHE 1968

Query: 178  GRPVEFHCRIGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDDPTADETSFIILQQAEL 357
            GR V  +CR  G    +  + W    KE G + P   +            S + L    +
Sbjct: 1969 GRTVRLYCRAAG--VPSASITW---RKEGGSL-PFRHQ---------AHGSRLRLHHMSV 2013

Query: 358  SDAGTYICTEPDTRDTARSILNV 426
            +D+G Y+C   +  D   + + +
Sbjct: 2014 ADSGEYVCRANNNIDAQETSIMI 2036
>sp|P98163|YL_DROME Putative vitellogenin receptor precursor (Yolkless protein) (YL)
          Length = 1984

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 26/56 (46%), Positives = 30/56 (53%)
 Frame = +1

Query: 676 GRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDP 843
           G ++A      D  C AG   CR+G CI  AK CDG+ DC D SDE     RLC P
Sbjct: 76  GGTAAGTPGSADTRCDAGQFQCRDGGCILQAKMCDGRGDCKDSSDELDCDYRLCRP 131

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 25/60 (41%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
 Frame = +1

Query: 637  TTNDNGTRFTCRKGRSSADVIVLVDPICTAGSRLCRNG-ECINSAKFCDGKRDCADGSDE 813
            T   NGT   C +G   AD       +C+     CR+G ECI     CDG++DC DGSDE
Sbjct: 1261 TVRCNGTT-ECPRGEDEADC----GDVCSIYEFKCRSGRECIRREFRCDGQKDCGDGSDE 1315

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
 Frame = +1

Query: 676  GRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDE-DQEFCRLCDP 843
            G +S +++      C  G   C +G CI  +  CDG+ DC+DGSDE D+   R C P
Sbjct: 1144 GDNSDELLCEATSRCEPGMFQCGSGSCIAGSWECDGRIDCSDGSDEHDKCVHRSCPP 1200

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
 Frame = +1

Query: 718 CTAGSRLCRNGECINSAKF-CDGKRDCADGSDEDQEFCRLCDP 843
           C     LC NG C+   ++ CDG  DC DGSDE +    LC+P
Sbjct: 227 CPGEGHLCANGRCLRRKQWVCDGVDDCGDGSDE-RGCLNLCEP 268

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 21/50 (42%), Positives = 27/50 (54%), Gaps = 1/50 (2%)
 Frame = +1

Query: 667 CRKGRSSADVIVLVDPICTAGSRLCRNGE-CINSAKFCDGKRDCADGSDE 813
           C  G      + L +P    G  LCRN E C+  ++ CDG  DC+DGSDE
Sbjct: 253 CGDGSDERGCLNLCEP--QKGKFLCRNRETCLTLSEVCDGHSDCSDGSDE 300

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 15/32 (46%), Positives = 19/32 (59%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            C      C NG+C++S+  CDG  DC D SDE
Sbjct: 1118 CHVHQHGCDNGKCVDSSLVCDGTNDCGDNSDE 1149

 Score = 38.9 bits (89), Expect = 0.018
 Identities = 19/42 (45%), Positives = 24/42 (57%), Gaps = 7/42 (16%)
 Frame = +1

Query: 739  CRNGECINSAKFCDGKRDCADGSDE---DQEFCR----LCDP 843
            C +GEC+     C+G+RDC D SDE   D+E  R    LC P
Sbjct: 1035 CHSGECLTMNHRCNGRRDCVDNSDEMNCDEEHRRKPKVLCSP 1076

 Score = 36.2 bits (82), Expect = 0.12
 Identities = 18/52 (34%), Positives = 23/52 (44%)
 Frame = +1

Query: 658  RFTCRKGRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            R  C  G    D  V     C    + C  G+C++ +  CDG  DC D SDE
Sbjct: 1180 RIDCSDGSDEHDKCV--HRSCPPDMQRCLLGQCLDRSLVCDGHNDCGDKSDE 1229

 Score = 34.7 bits (78), Expect = 0.34
 Identities = 13/34 (38%), Positives = 21/34 (61%), Gaps = 1/34 (2%)
 Frame = +1

Query: 715  ICTAGSRLCRNGE-CINSAKFCDGKRDCADGSDE 813
            +C+     C +GE C++  + CD ++DC D SDE
Sbjct: 1073 LCSPNQFACHSGEQCVDKERRCDNRKDCHDHSDE 1106

 Score = 33.9 bits (76), Expect = 0.58
 Identities = 11/33 (33%), Positives = 20/33 (60%)
 Frame = +1

Query: 739  CRNGECINSAKFCDGKRDCADGSDEDQEFCRLC 837
            C++GEC++ ++ C+   DC +G DE  +    C
Sbjct: 1347 CQDGECVDLSRVCNNFPDCTNGHDEGPKCATAC 1379
>sp|Q06561|UNC52_CAEEL Basement membrane proteoglycan precursor (Perlecan homolog)
           (Uncoordinated protein 52)
          Length = 3375

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 44/170 (25%), Positives = 62/170 (36%), Gaps = 12/170 (7%)
 Frame = +1

Query: 370 TYICTEPDTRDTARSILNVISDLRIVVTPPIIKLRAGQTATFQCYVLNGGRSADHPDFFM 549
           TY   + D  DT        SD++I V P   ++R G+  +F+C       S      + 
Sbjct: 31  TYQDIDSDDDDT--------SDVQITVFPSEKEVRDGRDVSFECRARTSDNSVYPTVRWA 82

Query: 550 ANGGRASDSQRTTVEKLEAGKVQLT----------YRAVTTNDNGTRFTCRKGRSSADVI 699
             GG    S   +  +L    VQL+          Y   T     T      G       
Sbjct: 83  RVGGPLPSSAHDSGGRLTINPVQLSDAGTYICVSDYNGNTVEARATLSVVSYGPQEVSNG 142

Query: 700 VLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQ--EFCRLCDP 843
           +     C A  + C N EC+ +   CDG+ DC D SDE       R C+P
Sbjct: 143 LRQAGQCMADEKACGNNECVKNDYVCDGEPDCRDRSDEANCPAISRTCEP 192

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 71/252 (28%), Positives = 95/252 (37%), Gaps = 26/252 (10%)
 Frame = +1

Query: 136 IEVNPNEETRRVGDGRPVEFHCRIGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDDPT 315
           I V P+E  + V DGR V F CR    RT +  V  T              RW+R   P 
Sbjct: 47  ITVFPSE--KEVRDGRDVSFECRA---RTSDNSVYPTV-------------RWARVGGPL 88

Query: 316 A----DETSFIILQQAELSDAGTYICTEPDTRDT--ARSILNVISDLRIVVTPPIIKLRA 477
                D    + +   +LSDAGTYIC      +T  AR+ L+V+S     V+  +   +A
Sbjct: 89  PSSAHDSGGRLTINPVQLSDAGTYICVSDYNGNTVEARATLSVVSYGPQEVSNGL--RQA 146

Query: 478 GQ-------TATFQC----YVLNGGRSADHPDFFMANGGRASDSQRTTVEKLE------- 603
           GQ           +C    YV +G      PD    +      +   T E  E       
Sbjct: 147 GQCMADEKACGNNECVKNDYVCDG-----EPDCRDRSDEANCPAISRTCEPNEFKCNNNK 201

Query: 604 -AGKVQLTYRAVTTNDNGTRFTCRKGRSSADVIVLVDPICTAGSRLCRN-GECINSAKFC 777
              K+ L        DN     C    SS+D        C      C +  +C+ S+  C
Sbjct: 202 CVQKMWLCDGDDDCGDNSDELNCNAKPSSSD--------CKPTEFQCHDRRQCVPSSFHC 253

Query: 778 DGKRDCADGSDE 813
           DG  DC DGSDE
Sbjct: 254 DGTNDCHDGSDE 265

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 49/173 (28%), Positives = 79/173 (45%), Gaps = 17/173 (9%)
 Frame = +1

Query: 91   ETKEAYIIVMAKSRTIEVNPNEETRRVGDGRPVEFHCRIGGYRTKNRDVVWTFMSKETGQ 270
            E+  A +IV +  R I ++P E+T  V +G P +  C + G+ +    V  TF  + +GQ
Sbjct: 1585 ESNPARVIVKSPIRPI-IDPAEQT--VPEGSPFKIRCYVPGHPS----VQLTFR-RVSGQ 1636

Query: 271  ITPLESRWSRSDDPTADETSFII-LQQAELSDAGTYICT--EPDTRDTARS------ILN 423
            +           +  ADE + ++ +Q+AEL+D G YICT  +PDT     S      + N
Sbjct: 1637 L-----------NEDADENNGLLAVQRAELTDEGDYICTARDPDTGAPIDSTPATVHVTN 1685

Query: 424  VISDLRI--------VVTPPIIKLRAGQTATFQCYVLNGGRSADHPDFFMANG 558
              +  ++        V+TP    +  G  A  QC V     +A H  F   +G
Sbjct: 1686 AAAPPQVEARPPQHPVITPQTQTIPEGDPARIQCTVPGNPSAAQHLSFERVDG 1738

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 41/154 (26%), Positives = 67/154 (43%), Gaps = 10/154 (6%)
 Frame = +1

Query: 76   CKVKGE-TKEAYIIVMAKSRTIEVNPNEETRRVG-DGRPVEFHCRIGGYRTKNRDVVWTF 249
            C+  G+ T E    V      + V   E  R++   G  V + C++ GY T+   V WT 
Sbjct: 1109 CEPIGQVTNEDITFVQKPHEVLRVRIMEPKRQIALPGDRVHWICQVTGYTTEKIHVEWT- 1167

Query: 250  MSKETGQITPLESRWSRSDDPTADE-TSFIILQQAELSDAGTYIC-----TEPDTRDTAR 411
               + G++         S  P A     +++L+  E  +AG Y C     T+  T D   
Sbjct: 1168 ---KVGEM---------SLPPNAKAYDGYLVLKGVEAENAGQYRCTATTITQYATDDALL 1215

Query: 412  SILNVISDL--RIVVTPPIIKLRAGQTATFQCYV 507
            +I   IS    + V+ PP + +  G+ A F+C+V
Sbjct: 1216 TISKRISGRPPQPVIDPPHLVVNEGEPAAFRCWV 1249

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 38/180 (21%), Positives = 71/180 (39%), Gaps = 22/180 (12%)
 Frame = +1

Query: 28   IMILQNIQQMNEGKYECKVKGETKEA---------YIIVMAKSRTIEVNPNE------ET 162
            ++ +Q  +  +EG Y C  +     A         ++   A    +E  P +      +T
Sbjct: 1647 LLAVQRAELTDEGDYICTARDPDTGAPIDSTPATVHVTNAAAPPQVEARPPQHPVITPQT 1706

Query: 163  RRVGDGRPVEFHCRIGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDDPTADETSFIIL 342
            + + +G P    C + G  +  + + +    +  G+  P  S         +D+   + +
Sbjct: 1707 QTIPEGDPARIQCTVPGNPSAAQHLSF---ERVDGKGLPFGS---------SDDRGVLTI 1754

Query: 343  QQAELSDAGTYICT-EPDTRDTAR---SILNVISD---LRIVVTPPIIKLRAGQTATFQC 501
               +L DAG Y+C   P+     +   S LNV  +    R V TPP++ +  G  A F C
Sbjct: 1755 PSTQLQDAGEYVCLYSPENSPPVKTNPSTLNVTPEGTPPRPVATPPLLSVAPGSPARFNC 1814

 Score = 38.9 bits (89), Expect = 0.018
 Identities = 32/134 (23%), Positives = 56/134 (41%), Gaps = 11/134 (8%)
 Frame = +1

Query: 139  EVNPNEETRRVGDGRPVEFHCRIGGYRTKNRDVVWTFMSKETGQITPLESRWSRSD---- 306
            +++P  +T  V D  P +F C + G                       + +WSR D    
Sbjct: 1417 QIDPPNQTVNVND--PAQFRCWVPGQPRA-------------------QLKWSRKDGRPL 1455

Query: 307  -DPTADETSFIILQQAELSDAGTYIC--TEPD----TRDTARSILNVISDLRIVVTPPII 465
             +   +   F+ + +++L DAG Y C  TEPD        AR  +N    ++  V PP+ 
Sbjct: 1456 PNGILERDGFLRIDKSQLHDAGEYECTSTEPDGSTQLSPPARLNVNQPQAIQPQVDPPVQ 1515

Query: 466  KLRAGQTATFQCYV 507
             +  G+ +  +C+V
Sbjct: 1516 TVNEGEPSRIRCWV 1529

 Score = 38.1 bits (87), Expect = 0.031
 Identities = 39/175 (22%), Positives = 71/175 (40%), Gaps = 10/175 (5%)
 Frame = +1

Query: 13   RLYVSIMILQNIQQMNEGKYECKVKGETKEAYI-IVMAKSRTIEVNPNEETRR-----VG 174
            + Y   ++L+ ++  N G+Y C     T+ A    ++  S+ I   P +         V 
Sbjct: 1179 KAYDGYLVLKGVEAENAGQYRCTATTITQYATDDALLTISKRISGRPPQPVIDPPHLVVN 1238

Query: 175  DGRPVEFHCRIGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDDPTADETSFIILQQAE 354
            +G P  F C + G      D   T+  ++ G   P                + + + Q++
Sbjct: 1239 EGEPAAFRCWVPGIP----DCQITWHREQLGGPLP---------HGVYQTGNALKIPQSQ 1285

Query: 355  LSDAGTYICTEPDTRDTARSILNVISDLRIVVTPPIIKLR----AGQTATFQCYV 507
            L  AG YIC+  +   T +S   V+   + V+ P +  +R      Q A F+C+V
Sbjct: 1286 LHHAGRYICSAANQYGTGQSPPAVLEVKKPVIPPKVDPIRQTVDRDQPARFKCWV 1340
>sp|P98160|PGBM_HUMAN Basement membrane-specific heparan sulfate proteoglycan core protein
            precursor (HSPG) (Perlecan) (PLC)
          Length = 4391

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 41/162 (25%), Positives = 67/162 (41%), Gaps = 4/162 (2%)
 Frame = +1

Query: 28   IMILQNIQQMNEGKYECKVKGETKEAYI---IVMAKSRTIEVNPNEETRRVGDGRPVEFH 198
            ++ +QN+ Q  +G Y C+  G   +A     +V+    ++ +N     + V  G  VEF 
Sbjct: 3450 VLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVEFE 3509

Query: 199  CRIGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDDPTADETSFIILQQAELSDAGTYI 378
            C   G       V W   SK  G + P                  + +   EL+DAG Y 
Sbjct: 3510 CLALG--DPKPQVTW---SKVGGHLRP----------GIVQSGGVVRIAHVELADAGQYR 3554

Query: 379  CTEPDTRDTARS-ILNVISDLRIVVTPPIIKLRAGQTATFQC 501
            CT  +   T +S +L ++  L  +  P  +++ AG  A F C
Sbjct: 3555 CTATNAAGTTQSHVLLLVQALPQISMPQEVRVPAGSAAVFPC 3596

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 39/175 (22%), Positives = 75/175 (42%), Gaps = 10/175 (5%)
 Frame = +1

Query: 13   RLYVSIMILQNIQQMNEGKYECKVK---GETKEAYIIVMAKSRTIEVNPNEETRRVGDGR 183
            +++  I+ L  ++  ++ +Y C+     G+     ++ +       V  + E  +V  GR
Sbjct: 1912 QIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGR 1971

Query: 184  PVEFHCRIGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDDPTADETSFIILQQAELSD 363
             V  +CR  G    +  + W    KE G + P ++R  R+D  T      +++     +D
Sbjct: 1972 TVRLYCRAAG--VPSATITWR---KEGGSLPP-QARSERTDIAT------LLIPAITTAD 2019

Query: 364  AGTYICTEPDTRDTARSILNVISDLRIVVTPPIIKLRA-------GQTATFQCYV 507
            AG Y+C       TA++ + V+       +PP +K+ +       GQT    C V
Sbjct: 2020 AGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVV 2074

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 17/32 (53%), Positives = 18/32 (56%)
 Frame = +1

Query: 718 CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
           C      CRNG CI     CDG+ DC DGSDE
Sbjct: 285 CGPQEAACRNGHCIPRDYLCDGQEDCEDGSDE 316

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 41/166 (24%), Positives = 71/166 (42%), Gaps = 13/166 (7%)
 Frame = +1

Query: 43   NIQQMNEGKYECKVKG----ETKEAYIIVM-AKSRTIEVNPNEE-TRRVGDGRPVEFHCR 204
            ++Q  + G Y C  +      T  A ++V  A S+ I V   E+ ++ V  G  V F C 
Sbjct: 1735 SVQPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICT 1794

Query: 205  IGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDDPTADETSFIILQQAELSDAGTYICT 384
                ++    +VWT +               +      D    + ++  +LSDAGTY+CT
Sbjct: 1795 AKS-KSPAYTLVWTRLHN------------GKLPTRAMDFNGILTIRNVQLSDAGTYVCT 1841

Query: 385  EPD--TRDTARSILNV-----ISDLRIVVTPPIIKLRAGQTATFQC 501
              +    D   + L+V     +S   + + PP + ++ GQ A F+C
Sbjct: 1842 GSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRC 1887

 Score = 39.7 bits (91), Expect = 0.011
 Identities = 33/142 (23%), Positives = 64/142 (45%), Gaps = 2/142 (1%)
 Frame = +1

Query: 28   IMILQNIQQMNEGKYECKVKGE--TKEAYIIVMAKSRTIEVNPNEETRRVGDGRPVEFHC 201
            ++ + +++  + G+Y C       T +++++++ ++      P E   RV  G    F C
Sbjct: 3539 VVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEV--RVPAGSAAVFPC 3596

Query: 202  RIGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDDPTADETSFIILQQAELSDAGTYIC 381
               GY T   D+ W   SK  G + P +SR          E + ++L      DAGTY+C
Sbjct: 3597 IASGYPTP--DISW---SKLDGSLPP-DSRL---------ENNMLMLPSVRPQDAGTYVC 3641

Query: 382  TEPDTRDTARSILNVISDLRIV 447
            T  + +   ++  ++    R+V
Sbjct: 3642 TATNRQGKVKAFAHLQVPERVV 3663

 Score = 37.4 bits (85), Expect = 0.053
 Identities = 45/171 (26%), Positives = 67/171 (39%), Gaps = 12/171 (7%)
 Frame = +1

Query: 25   SIMILQNIQQMNEGKYECKVKGETKEAYIIVMAKSR---TIEVNPNEETRRVGDGRPVEF 195
            SI+ +   +  N G Y C        A  +V        T+ V P E    V  G+ V  
Sbjct: 3074 SIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLP-EGPVWVKVGKAVTL 3132

Query: 196  HCRIGGY-RTKNRDVVWTFMSKETGQITPLESRWSRSDDPTADETSFIILQQAELSDAGT 372
             C   G  R+  R   WT +S    +   LE R         D  + + +  A+ SDAGT
Sbjct: 3133 ECVSAGEPRSSAR---WTRISSTPAK---LEQRTYG----LMDSHAVLQISSAKPSDAGT 3182

Query: 373  YICTEPDTRDTARSILNVISDL--------RIVVTPPIIKLRAGQTATFQC 501
            Y+C   +   TA+  + VI D         ++      + + AG TAT +C
Sbjct: 3183 YVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRC 3233

 Score = 32.7 bits (73), Expect = 1.3
 Identities = 27/92 (29%), Positives = 36/92 (39%), Gaps = 6/92 (6%)
 Frame = +1

Query: 244  TFMSKETGQITPLESRWSRSDDPTAD----ETSFIILQQAELSDAGTYIC--TEPDTRDT 405
            T     TG   P    WS+   P       E   +I+ +    D+G YIC  T P     
Sbjct: 3230 TLRCSATGSPAPT-IHWSKLRSPLPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAGHAE 3288

Query: 406  ARSILNVISDLRIVVTPPIIKLRAGQTATFQC 501
            A  IL+V S       P    ++AG+T   QC
Sbjct: 3289 ATIILHVESPPYATTVPEHASVQAGETVQLQC 3320

 Score = 31.2 bits (69), Expect = 3.8
 Identities = 14/34 (41%), Positives = 15/34 (44%)
 Frame = +1

Query: 712 PICTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
           P C      C NG C      CDG  DC D +DE
Sbjct: 323 PPCEPNEFPCGNGHCALKLWRCDGDFDCEDRTDE 356

 Score = 30.8 bits (68), Expect = 5.0
 Identities = 39/189 (20%), Positives = 73/189 (38%), Gaps = 26/189 (13%)
 Frame = +1

Query: 28   IMILQNIQQMNEGKYECKVKGE--TKEAYIIVMAKSRTIEVNP----------NEETRRV 171
            ++ L  +   + G+Y C+V G   T EA ++V  +  +    P             +  V
Sbjct: 2877 LLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHV 2936

Query: 172  GDGRPVEFHCRIGGYRTKNRDVVWTFMSKETGQITPLESRWSRSDDPTADET--SFIILQ 345
             +G+ ++ +C + G    +  V W    K  G +            P   +T  S + L 
Sbjct: 2937 TEGQTLDLNCVVPGQA--HAQVTWY---KRGGSL------------PARHQTHGSQLRLH 2979

Query: 346  QAELSDAGTYIC---TEPDTRDTARSILNV---------ISDLRIVVTPPIIKLRAGQTA 489
                +D+G Y+C   + P     A   + V         +    I + PP   ++ GQ A
Sbjct: 2980 LVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDA 3039

Query: 490  TFQCYVLNG 516
            +F+C + +G
Sbjct: 3040 SFKCLIHDG 3048
>sp|Q9NZR2|LRP1B_HUMAN Low-density lipoprotein receptor-related protein 1B precursor
           (Low-density lipoprotein receptor-related
           protein-deleted in tumor) (LRP-DIT)
          Length = 4599

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 25/62 (40%), Positives = 31/62 (50%)
 Frame = +1

Query: 643 NDNGTRFTCRKGRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQE 822
           ++NGT  T   G +       +  IC AG   C+N  CI +   CDG  DC DGSDED  
Sbjct: 827 DENGTTCTFNPGEA-------LPHICKAGEFRCKNRHCIQARWKCDGDDDCLDGSDEDSV 879

Query: 823 FC 828
            C
Sbjct: 880 NC 881

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 19/32 (59%), Positives = 23/32 (71%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            CT    LC NG+C++S  +CDG  DCADGSDE
Sbjct: 3515 CTLKDFLCANGDCVSSRFWCDGDFDCADGSDE 3546

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 17/32 (53%), Positives = 20/32 (62%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            C +   +C+NG CI S   CD K DC DGSDE
Sbjct: 2891 CNSSFFMCKNGRCIPSGGLCDNKDDCGDGSDE 2922

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 18/47 (38%), Positives = 24/47 (51%)
 Frame = +1

Query: 673  KGRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            K +S   ++   +  C  G + C N  CI   K CDG+ DC D SDE
Sbjct: 2537 KDKSDEKLLYCENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDE 2583

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 15/34 (44%), Positives = 24/34 (70%)
 Frame = +1

Query: 712  PICTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            P C++   +C +  CI+++  C+G+ DCADGSDE
Sbjct: 3592 PTCSSREYICASDGCISASLKCNGEYDCADGSDE 3625

 Score = 39.7 bits (91), Expect = 0.011
 Identities = 22/51 (43%), Positives = 23/51 (45%), Gaps = 9/51 (17%)
 Frame = +1

Query: 718  CTAGSRLCRN---------GECINSAKFCDGKRDCADGSDEDQEFCRLCDP 843
            C    RLC +         G CIN A  CDG  DC D SDED     LC P
Sbjct: 1088 CNGTIRLCDHKTKFSCWSTGRCINKAWVCDGDIDCEDQSDEDDCDSFLCGP 1138

 Score = 38.5 bits (88), Expect = 0.024
 Identities = 17/38 (44%), Positives = 19/38 (50%)
 Frame = +1

Query: 715  ICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFC 828
            IC A   LC N  C      CDG+ DC D SDE  + C
Sbjct: 3673 ICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMC 3710

 Score = 37.7 bits (86), Expect = 0.041
 Identities = 14/26 (53%), Positives = 18/26 (69%)
 Frame = +1

Query: 736  LCRNGECINSAKFCDGKRDCADGSDE 813
            +C++G CI+S   CD   DC DGSDE
Sbjct: 974  VCKSGRCISSKWHCDSDDDCGDGSDE 999

 Score = 37.4 bits (85), Expect = 0.053
 Identities = 15/40 (37%), Positives = 19/40 (47%)
 Frame = +1

Query: 709  DPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFC 828
            D  C+     C   +CI+    CDG+ DC DG DE    C
Sbjct: 2717 DSSCSWNQFACSAQKCISKHWICDGEDDCGDGLDESDSIC 2756

 Score = 36.2 bits (82), Expect = 0.12
 Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 2/44 (4%)
 Frame = +1

Query: 715  ICTAGSRLCRNGE--CINSAKFCDGKRDCADGSDEDQEFCRLCD 840
            +C      C N    C+   K C+GK+DC DGSDE      LCD
Sbjct: 1135 LCGPPKHPCANDTSVCLQPEKLCNGKKDCPDGSDEGY----LCD 1174

 Score = 36.2 bits (82), Expect = 0.12
 Identities = 13/25 (52%), Positives = 17/25 (68%)
 Frame = +1

Query: 739  CRNGECINSAKFCDGKRDCADGSDE 813
            C +G CI +   CDG++DC DG DE
Sbjct: 2689 CPSGRCILNTWICDGQKDCEDGRDE 2713

 Score = 35.8 bits (81), Expect = 0.15
 Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
 Frame = +1

Query: 715 ICTAGSRLCRNG-ECINSAKFCDGKRDCADGSDEDQEFC 828
           +C  G  LC +   C++ +  CDG  DC D SDE  + C
Sbjct: 31  LCDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDESLDTC 69

 Score = 35.8 bits (81), Expect = 0.15
 Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 3/44 (6%)
 Frame = +1

Query: 718  CTAGSRLCR-NGECINSAKFCDGKRDCADGSDED--QEFCRLCD 840
            C      C  +G C+     CDG++DC DGSDE       RLCD
Sbjct: 1053 CNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKGCNGTIRLCD 1096

 Score = 35.8 bits (81), Expect = 0.15
 Identities = 18/38 (47%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
 Frame = +1

Query: 718  CTAGSRL-CRNGECINSAKFCDGKRDCADGSDEDQEFC 828
            C A S   C NGECI+    CDG   C D SDE   +C
Sbjct: 2510 CNAYSEFECGNGECIDYQLTCDGIPHCKDKSDEKLLYC 2547

 Score = 35.4 bits (80), Expect = 0.20
 Identities = 15/49 (30%), Positives = 19/49 (38%)
 Frame = +1

Query: 682  SSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFC 828
            S  D +   +  C      C+N  CI     CDG  DC    DE  + C
Sbjct: 874  SDEDSVNCFNHSCPDDQFKCQNNRCIPKRWLCDGANDCGSNEDESNQTC 922

 Score = 35.4 bits (80), Expect = 0.20
 Identities = 23/73 (31%), Positives = 28/73 (38%), Gaps = 15/73 (20%)
 Frame = +1

Query: 655  TRFTCRKGR---------------SSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKR 789
            T+F C+ GR                 +D +  V   C      C +G CI     CDG  
Sbjct: 971  TQFVCKSGRCISSKWHCDSDDDCGDGSDEVGCVHS-CFDNQFRCSSGRCIPGHWACDGDN 1029

Query: 790  DCADGSDEDQEFC 828
            DC D SDE Q  C
Sbjct: 1030 DCGDFSDEAQINC 1042

 Score = 35.4 bits (80), Expect = 0.20
 Identities = 15/32 (46%), Positives = 16/32 (50%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            C  G   C  G C   A  CDG+ DC D SDE
Sbjct: 3357 CQPGRFQCGTGLCALPAFICDGENDCGDNSDE 3388

 Score = 35.4 bits (80), Expect = 0.20
 Identities = 16/42 (38%), Positives = 21/42 (50%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDP 843
            C+     C NG+CI +   CDG  DC  G DE     + C+P
Sbjct: 3553 CSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDE-----KSCEP 3589

 Score = 34.7 bits (78), Expect = 0.34
 Identities = 18/45 (40%), Positives = 21/45 (46%), Gaps = 2/45 (4%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRL--CDPL 846
            C      C NG CI  A  CD + DC D +DE    C    C+PL
Sbjct: 927  CQVDQFSCGNGRCIPRAWLCDREDDCGDQTDE-MASCEFPTCEPL 970

 Score = 34.3 bits (77), Expect = 0.45
 Identities = 14/35 (40%), Positives = 17/35 (48%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQE 822
            C   + +C N  CI     CD   DC DGSDE  +
Sbjct: 2805 CDENAFMCHNKVCIPKQFVCDHDDDCGDGSDESPQ 2839

 Score = 33.9 bits (76), Expect = 0.58
 Identities = 15/33 (45%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
 Frame = +1

Query: 718  CTAGSRLCRNGE-CINSAKFCDGKRDCADGSDE 813
            C A    C+    C+     CDG+RDC DGSDE
Sbjct: 2761 CAADMFSCQGSRACVPRHWLCDGERDCPDGSDE 2793

 Score = 33.9 bits (76), Expect = 0.58
 Identities = 15/35 (42%), Positives = 18/35 (51%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQE 822
            CTA    C+  +CI     CD   DC DGSDE  +
Sbjct: 3317 CTASQFRCKTDKCIPFWWKCDTVDDCGDGSDEPDD 3351

 Score = 33.9 bits (76), Expect = 0.58
 Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 3/37 (8%)
 Frame = +1

Query: 739  CRNGECINSAKFCDGKRDCADGSDEDQ---EFCRLCD 840
            C+N  CI     CD + DC+D SDE+    + C L D
Sbjct: 3483 CKNNNCIPDHWRCDSQNDCSDNSDEENCKPQTCTLKD 3519

 Score = 33.9 bits (76), Expect = 0.58
 Identities = 18/53 (33%), Positives = 22/53 (41%), Gaps = 1/53 (1%)
 Frame = +1

Query: 661  FTCRKGRSSADVIVLVDPICTAGSRLCRN-GECINSAKFCDGKRDCADGSDED 816
            + C  G    D +      C      C+N   CI     CDG  DC DGSDE+
Sbjct: 3617 YDCADGSDEMDCVTE----CKEDQFRCKNKAHCIPIRWLCDGIHDCVDGSDEE 3665

 Score = 32.3 bits (72), Expect = 1.7
 Identities = 13/27 (48%), Positives = 17/27 (62%), Gaps = 1/27 (3%)
 Frame = +1

Query: 739  CRNGE-CINSAKFCDGKRDCADGSDED 816
            CRN   C+ S + C+G  +C D SDED
Sbjct: 3723 CRNNRICLQSEQMCNGIDECGDNSDED 3749

 Score = 32.0 bits (71), Expect = 2.2
 Identities = 16/39 (41%), Positives = 19/39 (48%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRL 834
            C      C N +CI     CD   DC DGSDE  + CR+
Sbjct: 3762 CKKDEFACSNKKCIPMDLQCDRLDDCGDGSDE--QGCRI 3798

 Score = 30.4 bits (67), Expect = 6.5
 Identities = 13/32 (40%), Positives = 16/32 (50%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            C      C +G CI  +  C+   DCAD SDE
Sbjct: 2591 CATVEFRCADGTCIPRSARCNQNIDCADASDE 2622
>sp|Q9JI18|LRP1B_MOUSE Low-density lipoprotein receptor-related protein 1B precursor
            (Low-density lipoprotein receptor-related protein-deleted
            in tumor) (LRP-DIT)
          Length = 4599

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 19/32 (59%), Positives = 24/32 (75%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            CT    LC NG+C++S  +CDG+ DCADGSDE
Sbjct: 3515 CTLKDFLCSNGDCVSSRFWCDGEFDCADGSDE 3546

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 19/38 (50%), Positives = 21/38 (55%)
 Frame = +1

Query: 715 ICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFC 828
           IC  G   C+N  CI +   CDG  DC DGSDED   C
Sbjct: 844 ICKPGEFRCKNKHCIQARWKCDGDDDCLDGSDEDSVTC 881

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 14/34 (41%), Positives = 25/34 (73%)
 Frame = +1

Query: 712  PICTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            P+C++   +C +G C++++  C+G+ DC DGSDE
Sbjct: 3592 PVCSSSEYMCASGGCLSASLKCNGEPDCVDGSDE 3625

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 17/47 (36%), Positives = 24/47 (51%)
 Frame = +1

Query: 673  KGRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            K +S   ++   +  C +G + C N  C+   K CDG  DC D SDE
Sbjct: 2537 KDKSDEKLLYCENRSCRSGFKPCYNRRCVPHGKLCDGTNDCGDSSDE 2583

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 16/32 (50%), Positives = 20/32 (62%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            C +   +C+NG CI S   CD + DC DGSDE
Sbjct: 2891 CNSSFFMCKNGRCIPSDGLCDIRDDCGDGSDE 2922

 Score = 38.9 bits (89), Expect = 0.018
 Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 1/36 (2%)
 Frame = +1

Query: 739  CRN-GECINSAKFCDGKRDCADGSDEDQEFCRLCDP 843
            CR+ G CIN+A  CDG  DC D SDE+     LC P
Sbjct: 1103 CRSTGRCINNAWVCDGDVDCEDQSDEEDCDSFLCGP 1138

 Score = 38.5 bits (88), Expect = 0.024
 Identities = 24/68 (35%), Positives = 27/68 (39%), Gaps = 2/68 (2%)
 Frame = +1

Query: 646  DNGTRFTCRKGRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEF 825
            D     TC +G S          IC     LC N  C      CDG+ DC D SDE  + 
Sbjct: 3660 DGSDEETCGRGGS----------ICRDDEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDM 3709

Query: 826  C--RLCDP 843
            C   LC P
Sbjct: 3710 CVKFLCPP 3717

 Score = 37.7 bits (86), Expect = 0.041
 Identities = 20/44 (45%), Positives = 23/44 (52%), Gaps = 3/44 (6%)
 Frame = +1

Query: 718  CTAGSRLCR-NGECINSAKFCDGKRDCADGSDED--QEFCRLCD 840
            C      CR +G CI     CDG++DC DGSDE       RLCD
Sbjct: 1053 CIGNEFQCRPDGNCIPDLWRCDGEKDCEDGSDEKGCNGTIRLCD 1096

 Score = 36.6 bits (83), Expect = 0.090
 Identities = 15/49 (30%), Positives = 19/49 (38%)
 Frame = +1

Query: 682  SSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFC 828
            S  D +   +  C      C+N  CI     CDG  DC    DE  + C
Sbjct: 874  SDEDSVTCFNHSCPDDQFKCQNNRCIPKRWLCDGANDCGSNEDESNQTC 922

 Score = 36.6 bits (83), Expect = 0.090
 Identities = 20/45 (44%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDE--DQEFCRLCDPL 846
            C A    C NG CI +A  CD + DC D +DE    EF   C+PL
Sbjct: 927  CQADQFSCGNGRCIPTAWLCDREDDCGDQTDEVASCEF-PTCEPL 970

 Score = 35.4 bits (80), Expect = 0.20
 Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
 Frame = +1

Query: 715 ICTAGSRLCRNG-ECINSAKFCDGKRDCADGSDEDQEFC 828
           +C  G  LC +   C++ +  CDG  DC D SDE  + C
Sbjct: 31  LCDPGEFLCHDHVTCVSQSWLCDGDPDCPDQSDESLDTC 69

 Score = 35.4 bits (80), Expect = 0.20
 Identities = 13/25 (52%), Positives = 17/25 (68%)
 Frame = +1

Query: 739  CRNGECINSAKFCDGKRDCADGSDE 813
            C +G CI +   CDG++DC DG DE
Sbjct: 2689 CPSGRCILNTWVCDGQKDCEDGLDE 2713

 Score = 35.4 bits (80), Expect = 0.20
 Identities = 15/32 (46%), Positives = 16/32 (50%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            C  G   C  G C   A  CDG+ DC D SDE
Sbjct: 3357 CQPGRFQCGTGLCALPAFICDGENDCGDNSDE 3388

 Score = 35.4 bits (80), Expect = 0.20
 Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 3/37 (8%)
 Frame = +1

Query: 739  CRNGECINSAKFCDGKRDCADGSDEDQ---EFCRLCD 840
            C+N  CI     CD + DC+D SDED    + C L D
Sbjct: 3483 CKNNNCIPDHWRCDNQNDCSDNSDEDNCKPQTCTLKD 3519

 Score = 35.4 bits (80), Expect = 0.20
 Identities = 15/42 (35%), Positives = 22/42 (52%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDP 843
            C+     C NG+C+++   CDG  DC  G DE     + C+P
Sbjct: 3553 CSKDQFQCSNGQCLSAKWKCDGHEDCKYGEDE-----KNCEP 3589

 Score = 34.7 bits (78), Expect = 0.34
 Identities = 14/29 (48%), Positives = 18/29 (62%)
 Frame = +1

Query: 754  CINSAKFCDGKRDCADGSDEDQEFCRLCD 840
            C+   K C+G++DC DGSDE      LCD
Sbjct: 1150 CLQPEKLCNGRKDCPDGSDEGD----LCD 1174

 Score = 34.7 bits (78), Expect = 0.34
 Identities = 14/40 (35%), Positives = 18/40 (45%)
 Frame = +1

Query: 709  DPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFC 828
            D  C+     C   +CI+    CDG+ DC D  DE    C
Sbjct: 2717 DSSCSWNQFACSVKKCISKHWICDGEDDCGDSLDESDSIC 2756

 Score = 34.3 bits (77), Expect = 0.45
 Identities = 15/33 (45%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
 Frame = +1

Query: 718  CTAGSRLCRNGE-CINSAKFCDGKRDCADGSDE 813
            C A    C+    C+     CDG+RDC DGSDE
Sbjct: 2761 CAADMFSCQGSHACVPQHWLCDGERDCPDGSDE 2793

 Score = 33.9 bits (76), Expect = 0.58
 Identities = 13/30 (43%), Positives = 17/30 (56%)
 Frame = +1

Query: 739  CRNGECINSAKFCDGKRDCADGSDEDQEFC 828
            C NG+C++    CDG   C D SDE   +C
Sbjct: 2518 CGNGDCVDYVLTCDGIPHCKDKSDEKLLYC 2547

 Score = 33.9 bits (76), Expect = 0.58
 Identities = 14/32 (43%), Positives = 16/32 (50%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            C   + +C N  CI     CD   DC DGSDE
Sbjct: 2805 CDENAFMCHNKVCIPKQFVCDHDDDCGDGSDE 2836

 Score = 33.9 bits (76), Expect = 0.58
 Identities = 15/35 (42%), Positives = 18/35 (51%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQE 822
            CTA    C+  +CI     CD   DC DGSDE  +
Sbjct: 3317 CTASQFRCKTDKCIPFWWKCDTVDDCGDGSDEPDD 3351

 Score = 33.1 bits (74), Expect = 1.00
 Identities = 12/26 (46%), Positives = 17/26 (65%)
 Frame = +1

Query: 736  LCRNGECINSAKFCDGKRDCADGSDE 813
            +C++G CI++   CD   DC D SDE
Sbjct: 974  ICKSGRCISNKWHCDTDDDCGDRSDE 999

 Score = 33.1 bits (74), Expect = 1.00
 Identities = 14/30 (46%), Positives = 15/30 (50%)
 Frame = +1

Query: 739  CRNGECINSAKFCDGKRDCADGSDEDQEFC 828
            C +G CI     CDG  DC D SDE    C
Sbjct: 1013 CSSGRCIPGHWACDGDNDCGDFSDETHINC 1042

 Score = 32.0 bits (71), Expect = 2.2
 Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 1/51 (1%)
 Frame = +1

Query: 667  CRKGRSSADVIVLVDPICTAGSRLCRN-GECINSAKFCDGKRDCADGSDED 816
            C  G    D ++     C      C+N   CI     CDG  DC DGSDE+
Sbjct: 3619 CVDGSDEMDCVIE----CKEDQFQCKNKAYCIPIRWLCDGIYDCVDGSDEE 3665

 Score = 32.0 bits (71), Expect = 2.2
 Identities = 13/27 (48%), Positives = 16/27 (59%), Gaps = 1/27 (3%)
 Frame = +1

Query: 739  CRNGE-CINSAKFCDGKRDCADGSDED 816
            CRN   C+   K C+G  DC D SDE+
Sbjct: 3723 CRNDRICLQLEKICNGINDCGDNSDEE 3749

 Score = 32.0 bits (71), Expect = 2.2
 Identities = 14/32 (43%), Positives = 14/32 (43%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            C      C N  CI     CD   DC DGSDE
Sbjct: 3762 CKKDEFTCSNRNCIPMELQCDSLDDCGDGSDE 3793

 Score = 30.8 bits (68), Expect = 5.0
 Identities = 16/44 (36%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
 Frame = +1

Query: 715  ICTAGSRLC-RNGECINSAKFCDGKRDCADGSDEDQEFCRLCDP 843
            +C AG   C +N +CI     C+G+ DC D  DE       C P
Sbjct: 3395 VCLAGQFKCTKNKKCIPVNLRCNGQDDCGDEEDEKDCPENSCSP 3438

 Score = 30.4 bits (67), Expect = 6.5
 Identities = 12/32 (37%), Positives = 17/32 (53%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            C+     C +G CI  +  C+   DC+D SDE
Sbjct: 2591 CSTVEFRCADGTCIPRSARCNQNMDCSDASDE 2622

 Score = 30.4 bits (67), Expect = 6.5
 Identities = 13/26 (50%), Positives = 16/26 (61%), Gaps = 1/26 (3%)
 Frame = +1

Query: 739  CRNGEC-INSAKFCDGKRDCADGSDE 813
            C +G C +N+   CDG  DC D SDE
Sbjct: 2852 CADGRCLVNTLWQCDGDFDCPDSSDE 2877
>sp|Q98930|SORL_CHICK Sortilin-related receptor (Sorting protein-related receptor
            containing LDLR class A repeats) (SorLA) (SorLA-1)
            (Low-density lipoprotein receptor relative with 11
            ligand-binding repeats) (LDLR relative with 11
            ligand-binding repeats) (LR11)
          Length = 1592

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 27/72 (37%), Positives = 33/72 (45%)
 Frame = +1

Query: 613  VQLTYRAVTTNDNGTRFTCRKGRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRD 792
            ++L++R    ND      CR     A+  +     C A S  C NG CI     CDG  D
Sbjct: 1078 IRLSWRCDDDND------CRDWSDEANCTMF--RTCEASSFQCLNGHCIPQRWACDGDAD 1129

Query: 793  CADGSDEDQEFC 828
            C DGSDED   C
Sbjct: 1130 CQDGSDEDPTIC 1141

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 21/48 (43%), Positives = 26/48 (54%)
 Frame = +1

Query: 673  KGRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDED 816
            +G     +   V P C      C +G CI ++  CDG RDCADGSDED
Sbjct: 1311 EGSPLLPITTAVPPTCLPNHFRCGSGACITNSWVCDGYRDCADGSDED 1358

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 17/33 (51%), Positives = 21/33 (63%)
 Frame = +1

Query: 739  CRNGECINSAKFCDGKRDCADGSDEDQEFCRLC 837
            C NG CI+++K C+G  DCAD SDE      LC
Sbjct: 1150 CPNGTCISTSKHCNGITDCADASDEQDCEIPLC 1182

 Score = 39.3 bits (90), Expect = 0.014
 Identities = 18/41 (43%), Positives = 19/41 (46%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCD 840
            C      C NG CINS   CD   DC D SDE      +CD
Sbjct: 985  CLPNQYRCFNGNCINSIWQCDNNNDCGDMSDEKNCPTTVCD 1025

 Score = 37.7 bits (86), Expect = 0.041
 Identities = 42/139 (30%), Positives = 58/139 (41%), Gaps = 16/139 (11%)
 Frame = +1

Query: 472  RAGQTATFQCYVLNGG----RSADHPDFFMANGGRASDSQRTTVEKLEAGKVQLTYRAVT 639
            R  + ++FQC  LNG     R A   D    +G   SD   T  EK   G        ++
Sbjct: 1103 RTCEASSFQC--LNGHCIPQRWACDGDADCQDG---SDEDPTICEKKCNGFQCPNGTCIS 1157

Query: 640  TNDNGTRFT-CRKGRSSADVIVLVDPICTAGSR-LCRNGE-CINSAKFCDGKRDCADGSD 810
            T+ +    T C       D  +   P+CT     +C+N + C++ +  CDG   C DGSD
Sbjct: 1158 TSKHCNGITDCADASDEQDCEI---PLCTRYMDFVCKNRQQCLSHSMVCDGDIQCEDGSD 1214

Query: 811  ED---------QEFCRLCD 840
            ED          EF R CD
Sbjct: 1215 EDANYAGCAQEPEFHRTCD 1233

 Score = 35.8 bits (81), Expect = 0.15
 Identities = 14/27 (51%), Positives = 17/27 (62%)
 Frame = +1

Query: 739  CRNGECINSAKFCDGKRDCADGSDEDQ 819
            C NG CI +   CDG+ DC D SDE +
Sbjct: 1283 CGNGHCIPNQWKCDGENDCGDWSDEKE 1309

 Score = 35.4 bits (80), Expect = 0.20
 Identities = 17/33 (51%), Positives = 22/33 (66%), Gaps = 1/33 (3%)
 Frame = +1

Query: 718  CTAGSRLCRNGE-CINSAKFCDGKRDCADGSDE 813
            C  G R C +GE C+ + + CDG  DC+DGSDE
Sbjct: 1421 CPQGYR-CEDGEACLLATERCDGYLDCSDGSDE 1452

 Score = 34.7 bits (78), Expect = 0.34
 Identities = 16/32 (50%), Positives = 17/32 (53%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            C   S  C NG CI+    CDG  DC D SDE
Sbjct: 1232 CDQFSFQCANGVCISLVWKCDGMDDCGDYSDE 1263

 Score = 34.7 bits (78), Expect = 0.34
 Identities = 13/21 (61%), Positives = 17/21 (80%)
 Frame = +1

Query: 751  ECINSAKFCDGKRDCADGSDE 813
            +CI + K CDG+RDC DG+DE
Sbjct: 1390 KCIPNWKRCDGRRDCQDGTDE 1410

 Score = 30.0 bits (66), Expect = 8.4
 Identities = 13/32 (40%), Positives = 15/32 (46%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            C      C +G CI  +  CD   DC D SDE
Sbjct: 1065 CRKDEFSCSSGMCIRLSWRCDDDNDCRDWSDE 1096
>sp|Q92673|SORL_HUMAN Sortilin-related receptor precursor (Sorting protein-related receptor
            containing LDLR class A repeats) (SorLA) (SorLA-1)
            (Low-density lipoprotein receptor relative with 11
            ligand-binding repeats) (LDLR relative with 11
            ligand-binding repeats) (LR11)
          Length = 2214

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 21/36 (58%), Positives = 24/36 (66%)
 Frame = +1

Query: 739  CRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPL 846
            C NG CI S+K CDG RDC+DGSDE       C+PL
Sbjct: 1244 CPNGTCIPSSKHCDGLRDCSDGSDEQH-----CEPL 1274

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 20/37 (54%), Positives = 21/37 (56%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFC 828
            C A +  CRNG CI     CDG  DC DGSDED   C
Sbjct: 1199 CEASNFQCRNGHCIPQRWACDGDTDCQDGSDEDPVNC 1235

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 16/33 (48%), Positives = 19/33 (57%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDED 816
            C      C +G C+     CDG RDCADGSDE+
Sbjct: 1419 CLPNYYRCSSGTCVMDTWVCDGYRDCADGSDEE 1451

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 18/41 (43%), Positives = 20/41 (48%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCD 840
            C      C NG CINS  +CD   DC D SDE      +CD
Sbjct: 1078 CLRNQYRCSNGNCINSIWWCDFDNDCGDMSDERNCPTTICD 1118

 Score = 36.6 bits (83), Expect = 0.090
 Identities = 15/32 (46%), Positives = 18/32 (56%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            C +    C +G CI S+  CDG  DC D SDE
Sbjct: 1158 CRSDEYNCSSGMCIRSSWVCDGDNDCRDWSDE 1189

 Score = 35.4 bits (80), Expect = 0.20
 Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
 Frame = +1

Query: 667  CRKGRSSADVIVLVDPICTAGSRLCRNGE-CINSAKFCDGKRDCADGSDE 813
            C+ GR  A+        C +    C +GE CI  ++ CDG  DC+D SDE
Sbjct: 1497 CQDGRDEANCPTHSTLTCMSREFQCEDGEACIVLSERCDGFLDCSDESDE 1546

 Score = 34.7 bits (78), Expect = 0.34
 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 11/55 (20%)
 Frame = +1

Query: 709  DPICTAGSR-LCRNGE-CINSAKFCDGKRDCADGSDE---------DQEFCRLCD 840
            +P+CT     +C+N + C+  +  CDG   C DGSDE         D EF ++CD
Sbjct: 1272 EPLCTHFMDFVCKNRQQCLFHSMVCDGIIQCRDGSDEDAAFAGCSQDPEFHKVCD 1326

 Score = 34.7 bits (78), Expect = 0.34
 Identities = 15/33 (45%), Positives = 18/33 (54%)
 Frame = +1

Query: 715  ICTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            +C      C+NG CI+    CDG  DC D SDE
Sbjct: 1324 VCDEFGFQCQNGVCISLIWKCDGMDDCGDYSDE 1356

 Score = 33.1 bits (74), Expect = 1.00
 Identities = 13/25 (52%), Positives = 15/25 (60%)
 Frame = +1

Query: 739  CRNGECINSAKFCDGKRDCADGSDE 813
            C NG CI +   CD + DC D SDE
Sbjct: 1376 CENGHCIPNRWKCDRENDCGDWSDE 1400

 Score = 30.8 bits (68), Expect = 5.0
 Identities = 12/20 (60%), Positives = 14/20 (70%)
 Frame = +1

Query: 754  CINSAKFCDGKRDCADGSDE 813
            CI + K CDG +DC DG DE
Sbjct: 1484 CIPNWKRCDGHQDCQDGRDE 1503
>sp|Q95209|SORL_RABIT Sortilin-related receptor precursor (Sorting protein-related receptor
            containing LDLR class A repeats) (SorLA) (SorLA-1)
            (Low-density lipoprotein receptor relative with 11
            ligand-binding repeats) (LDLR relative with 11
            ligand-binding repeats) (LR11)
          Length = 2213

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 20/37 (54%), Positives = 21/37 (56%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFC 828
            C A +  CRNG CI     CDG  DC DGSDED   C
Sbjct: 1198 CEASNFQCRNGHCIPQRWACDGDADCQDGSDEDPANC 1234

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 20/36 (55%), Positives = 22/36 (61%)
 Frame = +1

Query: 739  CRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDPL 846
            C NG CI S K CDG  DC+DGSDE       C+PL
Sbjct: 1243 CPNGTCIPSTKHCDGLHDCSDGSDEQH-----CEPL 1273

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 22/59 (37%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
 Frame = +1

Query: 667  CRKGRS-SADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCD 840
            C KG     +  V  +  C      C NG CINS  +CD   DC D SDE      +CD
Sbjct: 1059 CPKGYELKNNTCVKEEDTCLRNQYRCSNGNCINSIWWCDFDNDCGDMSDEKNCPTTICD 1117

 Score = 39.3 bits (90), Expect = 0.014
 Identities = 16/33 (48%), Positives = 18/33 (54%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDED 816
            C      C  G C+     CDG RDCADGSDE+
Sbjct: 1418 CLPNYYRCGGGACVIDTWVCDGYRDCADGSDEE 1450

 Score = 36.6 bits (83), Expect = 0.090
 Identities = 15/32 (46%), Positives = 18/32 (56%)
 Frame = +1

Query: 718  CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            C +    C +G CI S+  CDG  DC D SDE
Sbjct: 1157 CRSDEYNCSSGMCIRSSWVCDGDNDCRDWSDE 1188

 Score = 35.0 bits (79), Expect = 0.26
 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 11/55 (20%)
 Frame = +1

Query: 709  DPICTAGSR-LCRNGE-CINSAKFCDGKRDCADGSDE---------DQEFCRLCD 840
            +P+CT     +C+N + C+  +  CDG   C DGSDE         D EF ++CD
Sbjct: 1271 EPLCTRFMDFVCKNRQQCLFHSMVCDGIIQCRDGSDEDPAFAGCSRDPEFHKVCD 1325

 Score = 34.7 bits (78), Expect = 0.34
 Identities = 15/33 (45%), Positives = 18/33 (54%)
 Frame = +1

Query: 715  ICTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
            +C      C+NG CI+    CDG  DC D SDE
Sbjct: 1323 VCDEFGFQCQNGVCISLIWKCDGMDDCGDYSDE 1355

 Score = 33.9 bits (76), Expect = 0.58
 Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
 Frame = +1

Query: 667  CRKGRSSADVIVLVDPICTAGSRLCRNGE-CINSAKFCDGKRDCADGSDE 813
            C+ G+  A+        C +    C +GE CI  ++ CDG  DC+D SDE
Sbjct: 1496 CQDGQDEANCPTHSTLTCMSWEFKCEDGEACIVLSERCDGFLDCSDESDE 1545

 Score = 32.3 bits (72), Expect = 1.7
 Identities = 13/25 (52%), Positives = 15/25 (60%)
 Frame = +1

Query: 739  CRNGECINSAKFCDGKRDCADGSDE 813
            C NG CI +   CD + DC D SDE
Sbjct: 1375 CDNGHCIPNRWKCDRENDCGDWSDE 1399

 Score = 30.4 bits (67), Expect = 6.5
 Identities = 11/21 (52%), Positives = 15/21 (71%)
 Frame = +1

Query: 751  ECINSAKFCDGKRDCADGSDE 813
            +CI + + CDG +DC DG DE
Sbjct: 1482 KCIPNWRRCDGHQDCQDGQDE 1502
>sp|P35952|LDLR_RAT Low-density lipoprotein receptor precursor (LDL receptor)
          Length = 879

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 20/43 (46%), Positives = 24/43 (55%)
 Frame = +1

Query: 700 VLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFC 828
           V  +  C      CR+G+CI S   CDG R+C DGSDE  E C
Sbjct: 21  VAAEDSCGKNEFQCRDGKCIVSKWVCDGSRECPDGSDESPETC 63

 Score = 38.1 bits (87), Expect = 0.031
 Identities = 16/30 (53%), Positives = 18/30 (60%)
 Frame = +1

Query: 739 CRNGECINSAKFCDGKRDCADGSDEDQEFC 828
           C +  CI S   CDG RDC DGSDE  + C
Sbjct: 155 CNSSSCIPSLWACDGDRDCDDGSDEWPQNC 184

 Score = 38.1 bits (87), Expect = 0.031
 Identities = 15/31 (48%), Positives = 20/31 (64%)
 Frame = +1

Query: 739 CRNGECINSAKFCDGKRDCADGSDEDQEFCR 831
           C +GECI+  K C+  RDC D SDE  + C+
Sbjct: 285 CHSGECISLDKVCNSARDCRDWSDEPIKECK 315

 Score = 37.4 bits (85), Expect = 0.053
 Identities = 20/62 (32%), Positives = 25/62 (40%)
 Frame = +1

Query: 658 RFTCRKGRSSADVIVLVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLC 837
           R  C  G    D        C+     C++G+CI+    CD   DC DGSDE       C
Sbjct: 92  RTDCENGSDELDCS---PKTCSLDEFRCQDGKCISRQFVCDQDWDCLDGSDEAHCAATTC 148

Query: 838 DP 843
            P
Sbjct: 149 GP 150

 Score = 37.0 bits (84), Expect = 0.069
 Identities = 17/47 (36%), Positives = 24/47 (51%)
 Frame = +1

Query: 703 LVDPICTAGSRLCRNGECINSAKFCDGKRDCADGSDEDQEFCRLCDP 843
           +V   C++    C + ECI+ +  CDG  DC D SDE+      C P
Sbjct: 193 VVSSPCSSLEFHCGSSECIHRSWVCDGAADCKDKSDEENCAVTTCRP 239

 Score = 33.9 bits (76), Expect = 0.58
 Identities = 13/32 (40%), Positives = 18/32 (56%)
 Frame = +1

Query: 718 CTAGSRLCRNGECINSAKFCDGKRDCADGSDE 813
           C      C +G CI+ ++ CD + DC D SDE
Sbjct: 237 CRPDEFQCADGSCIHGSRQCDREHDCKDMSDE 268

 Score = 32.3 bits (72), Expect = 1.7
 Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 9/40 (22%)
 Frame = +1

Query: 721 TAGSRLCRNGE---------CINSAKFCDGKRDCADGSDE 813
           T  S  CR+GE         CI  +  CDG+ DC +GSDE
Sbjct: 62  TCMSVTCRSGEFSCGGRVSRCIPDSWRCDGRTDCENGSDE 101
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,371,738
Number of Sequences: 369166
Number of extensions: 1885665
Number of successful extensions: 6604
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5495
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6561
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8341863645
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)