DrC_00820
- Cluster detail
- GO Category :
- Consensus Sequence :
BLASTX 2.2.13 [Nov-27-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00820 (1700 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 ... 347 8e-95 sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 ... 345 2e-94 sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1) 342 2e-93 sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1) 341 3e-93 sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1) 341 3e-93 sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein ... 339 1e-92 sp|P17225|PTBP1_MOUSE Polypyrimidine tract-binding protein ... 316 1e-85 sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprote... 119 2e-26 sp|Q921F4|HNRLL_MOUSE Heterogeneous nuclear ribonucleoprote... 113 2e-24 sp|Q8R081|HNRPL_MOUSE Heterogeneous nuclear ribonucleoprote... 82 6e-15
>sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I) (Pyrimidine-binding protein) (PYBP) Length = 555 Score = 347 bits (889), Expect = 8e-95 Identities = 205/536 (38%), Positives = 298/536 (55%), Gaps = 14/536 (2%) Frame = +1 Query: 82 NSHKKVKMDQGNDNKPSRVIHIRNVPQEVDDTAVAMLAVPFGYIDNIVFVRKNNQALIQM 261 N KK K D + PSRVIH+R +P +V + V L +PFG + N++ ++ NQA I+M Sbjct: 41 NDSKKFKGDNRSTGVPSRVIHVRKLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEM 100 Query: 262 REISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQL--DLRNNNSNIDKLVQHANEKRKHY 435 A M +Y+ P++ G+ ++IQFS H++L D N + +Q N + Sbjct: 101 STEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGN 160 Query: 436 L--------VNWSNNTGGASEILRILIDNAPNLVINHLVFYKIFSRFGQIIRIVSFTKNN 591 L V+ G S +LRI+++N V V ++IFS+FG +++I++FTKNN Sbjct: 161 LALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLD-VLHQIFSKFGTVLKIITFTKNN 219 Query: 592 QHHGLVEFVNPLAAHVAQLQLNGANLLGDCGTMRIDFSKNPGPLQVQRQSDKVRDYLESP 771 Q L+++ +P++A A+L L+G N+ C T+RIDFSK L V+ +DK RDY Sbjct: 220 QFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTS-LNVKYNNDKSRDYTRPD 278 Query: 772 LTRNEMQELEGPQYGFPLFAVGRSPSMSRGNEQFMTAQLSA---MASQTGVELTPXXXXX 942 L + Q PS+ +Q M A A M++ P Sbjct: 279 LPSGDSQ-----------------PSL----DQTMAAAFGAPGIMSASPYAGAVPSHLCH 317 Query: 943 XXXXXXXCNQMNHRSTDQSNWGFGSNQTQSSMFSSNTGIDSGNSVVLVTNLNAEKSNPDA 1122 ++ + + + + +GNSV+LV+NLN E+ P + Sbjct: 318 PSRAGLSVPNVHGALAPLAIPSAAAAAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQS 377 Query: 1123 LFTLFGVYGDVMRVKVMFNKKNTALVQFANHQQAMTAIRNLDACFLWGKQMHLHVSKTNV 1302 LF LFGVYGDV RVK++FNKK ALV+ A+ QA A+ +L+ L GK + + +SK Sbjct: 378 LFILFGVYGDVQRVKILFNKKENALVEMADGSQAQLAMSHLNGHKLHGKSVRITLSKHQS 437 Query: 1303 IQLPME-DANHGLTKDYSNSTLHRFKKPNSKNYQNIFPPSAVLHLSNIPPTTGEGDLSEM 1479 +QLP E + GLTKDY +S LHRFKKP SKN+QNIFPPSA LHLSNIPP+ E DL + Sbjct: 438 VQLpreGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEDDLKSL 497 Query: 1480 IRSSGFEIKKFKFLPNDKKMALLELNSVEDAIHVLIDFHNHKLSEKNHLRISFSKA 1647 S+G +K FKF D+KMAL+++ SVE+A+ LI+ HNH L E +HLR+SFSK+ Sbjct: 498 FSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGENHHLRVSFSKS 553
>sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I) Length = 557 Score = 345 bits (886), Expect = 2e-94 Identities = 211/539 (39%), Positives = 296/539 (54%), Gaps = 17/539 (3%) Frame = +1 Query: 82 NSHKKVKMDQGNDNKPSRVIHIRNVPQEVDDTAVAMLAVPFGYIDNIVFVRKNNQALIQM 261 N KK K D + PSRVIHIR +P +V + V L +PFG + N++ ++ NQA I+M Sbjct: 42 NDSKKFKGDNRSAGVPSRVIHIRKLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEM 101 Query: 262 REISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQL--DLRNNNSNIDKLVQHANEKRKHY 435 A M +Y+ P++ G+ ++IQFS H++L D N + +Q N + Sbjct: 102 NTEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGN 161 Query: 436 L--------VNWSNNTGGASEILRILIDNAPNLVINHLVFYKIFSRFGQIIRIVSFTKNN 591 L V+ G S +LRI+++N V V ++IFS+FG +++I++FTKNN Sbjct: 162 LALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLD-VLHQIFSKFGTVLKIITFTKNN 220 Query: 592 QHHGLVEFVNPLAAHVAQLQLNGANLLGDCGTMRIDFSKNPGPLQVQRQSDKVRDYLESP 771 Q L+++ +P++A A+L L+G N+ C T+RIDFSK L V+ +DK RDY Sbjct: 221 QFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTS-LNVKYNNDKSRDYTRPD 279 Query: 772 LTRNEMQ----ELEGPQYGFPLFAVGRSPSMSRGNEQFMTAQLSAMASQTGVE--LTPXX 933 L + Q + +G P + SP G +A S V L P Sbjct: 280 LPSGDNQPSLDQTMAAAFGAPGI-MSASPYAGAGFPPTFAIPQAATVSVPNVHGALAPLA 338 Query: 934 XXXXXXXXXXCNQMNHRSTDQSNWGFGSNQTQSSMFSSNTGIDSGNSVVLVTNLNAEKSN 1113 + + + +GNSV+LV+NLN E+ Sbjct: 339 IPSA----------------------AARAAAAGRIAIPGLAGAGNSVLLVSNLNPERVT 376 Query: 1114 PDALFTLFGVYGDVMRVKVMFNKKNTALVQFANHQQAMTAIRNLDACFLWGKQMHLHVSK 1293 P +LF LFGVY DV RVK++FNKK ALVQ A+ QA A+ +L+ L GK + + +SK Sbjct: 377 PQSLFILFGVYCDVQRVKILFNKKENALVQMADGSQAQLAMSHLNGHKLHGKPVRITLSK 436 Query: 1294 TNVIQLPME-DANHGLTKDYSNSTLHRFKKPNSKNYQNIFPPSAVLHLSNIPPTTGEGDL 1470 +QLP E + GLTKDY NS LHRFKKP SKN+QNIFPPSA LHLSNIPP+ E DL Sbjct: 437 HQNVQLpreGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSISEEDL 496 Query: 1471 SEMIRSSGFEIKKFKFLPNDKKMALLELNSVEDAIHVLIDFHNHKLSEKNHLRISFSKA 1647 + S+G +K FKF D+KMAL+++ SVE+AI LID HNH L E +HLR+SFSK+ Sbjct: 497 KILFSSNGGIVKGFKFFQKDRKMALIQMGSVEEAIQALIDLHNHDLGENHHLRVSFSKS 555
>sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1) Length = 523 Score = 342 bits (877), Expect = 2e-93 Identities = 210/536 (39%), Positives = 290/536 (54%), Gaps = 24/536 (4%) Frame = +1 Query: 112 GNDNK----------PSRVIHIRNVPQEVDDTAVAMLAVPFGYIDNIVFVRKNNQALIQM 261 GNDNK PSRV+H+R +P +V + V L +PFG + N++ ++ +QA ++M Sbjct: 13 GNDNKKFKGDRPPCSPSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEM 72 Query: 262 REISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQLDLRN--NNSNIDKLVQ--HANEKRK 429 A+ M +Y+ P + + ++IQ+S H++L N N + +Q A + Sbjct: 73 ASEEAAVTMINYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGN 132 Query: 430 HYLVNWSNNTG----GASEILRILIDNAPNLVINHLVFYKIFSRFGQIIRIVSFTKNNQH 597 L ++N G G S +LRI+I+N V V ++IFS+FG +++I++FTKNNQ Sbjct: 133 LSLPGATSNEGTLLPGQSPVLRIIIENLFYPVTLE-VLHQIFSKFGTVLKIITFTKNNQF 191 Query: 598 HGLVEFVNPLAAHVAQLQLNGANLLGDCGTMRIDFSKNPGPLQVQRQSDKVRDYLESPLT 777 L+++ +P+ A A++ L+G N+ C T+RIDFSK L V+ +DK RD+ L Sbjct: 192 QALLQYADPVNAQYAKMALDGQNIYNACCTLRIDFSKLTS-LNVKYNNDKSRDFTRLDLP 250 Query: 778 RNEMQELEGPQYGFPLFAVGRSPSMSRGNEQFMTAQLSAMASQTGVELTPXXXXXXXXXX 957 + Q P A G S G F A A+ V P Sbjct: 251 TGDGQPSLEPPMAAAFGAPGIMSSPYAGAAGFAPAIAFPQAAGLSVSAVPG--------- 301 Query: 958 XXCNQMNHRSTDQSNWGFGSNQTQSSMFSSNTGIDS-----GNSVVLVTNLNAEKSNPDA 1122 G SS S I GNSV+LVTNLN + P Sbjct: 302 ----------------ALGPLTLTSSAVSGRMAIPGASGIPGNSVLLVTNLNPDFITPHG 345 Query: 1123 LFTLFGVYGDVMRVKVMFNKKNTALVQFANHQQAMTAIRNLDACFLWGKQMHLHVSKTNV 1302 LF LFGVYGDV RVK+MFNKK ALVQ A+ QA A+ +L L+GK + +SK Sbjct: 346 LFILFGVYGDVHRVKIMFNKKENALVQMADASQAQIAMNHLSGQRLYGKVLRATLSKHQA 405 Query: 1303 IQLPME-DANHGLTKDYSNSTLHRFKKPNSKNYQNIFPPSAVLHLSNIPPTTGEGDLSEM 1479 +QLP E + GLTKD+SNS LHRFKKP SKN+QNIFPPSA LHLSNIPP+ DL + Sbjct: 406 VQLpreGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNL 465 Query: 1480 IRSSGFEIKKFKFLPNDKKMALLELNSVEDAIHVLIDFHNHKLSEKNHLRISFSKA 1647 +G +K FKF D+KMAL++L SVE+AI LI+ HNH L E +HLR+SFSK+ Sbjct: 466 FTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKS 521
>sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1) Length = 523 Score = 341 bits (875), Expect = 3e-93 Identities = 209/536 (38%), Positives = 285/536 (53%), Gaps = 24/536 (4%) Frame = +1 Query: 112 GNDNK----------PSRVIHIRNVPQEVDDTAVAMLAVPFGYIDNIVFVRKNNQALIQM 261 GNDNK PSRV+H+R +P +V + V L +PFG + N++ ++ +QA ++M Sbjct: 13 GNDNKKFKGDRPPCSPSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEM 72 Query: 262 REISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQLDLRN--NNSNID------KLVQHAN 417 A+ M +Y+ P + + ++IQ+S H++L N N + VQ N Sbjct: 73 ASEEAAVTMINYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGN 132 Query: 418 EKRKHYLVNWSNNTGGASEILRILIDNAPNLVINHLVFYKIFSRFGQIIRIVSFTKNNQH 597 N G S +LRI+I+N V V ++IFS+FG +++I++FTKNNQ Sbjct: 133 LSLPGATANEGTLLPGQSPVLRIIIENLFYPVTLE-VLHQIFSKFGTVLKIITFTKNNQF 191 Query: 598 HGLVEFVNPLAAHVAQLQLNGANLLGDCGTMRIDFSKNPGPLQVQRQSDKVRDYLESPLT 777 L+++ +P+ A A++ L+G N+ C T+RIDFSK L V+ +DK RD+ L Sbjct: 192 QALLQYADPVNAQYAKMALDGQNIYNACCTLRIDFSKLTS-LNVKYNNDKSRDFTRLDLP 250 Query: 778 RNEMQELEGPQYGFPLFAVGRSPSMSRGNEQFMTAQLSAMASQTGVELTPXXXXXXXXXX 957 + Q P A G S G F A A+ V P Sbjct: 251 TGDGQPSLEPPMAAAFGAPGIMSSPYAGAAGFAPAIAFPQAAGLSVPAVPG--------- 301 Query: 958 XXCNQMNHRSTDQSNWGFGSNQTQSSMFSSNTGIDS-----GNSVVLVTNLNAEKSNPDA 1122 G SS S I GNSV+LVTNLN + P Sbjct: 302 ----------------ALGPLTLTSSAVSGRMAIPGASGMPGNSVLLVTNLNPDFITPHG 345 Query: 1123 LFTLFGVYGDVMRVKVMFNKKNTALVQFANHQQAMTAIRNLDACFLWGKQMHLHVSKTNV 1302 LF LFGVYGDV RVK+MFNKK ALVQ A+ QA A+ +L L+GK + +SK Sbjct: 346 LFILFGVYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQA 405 Query: 1303 IQLPME-DANHGLTKDYSNSTLHRFKKPNSKNYQNIFPPSAVLHLSNIPPTTGEGDLSEM 1479 +QLP E + GLTKD+SNS LHRFKKP SKN+QNIFPPSA LHLSNIPP+ DL + Sbjct: 406 VQLpreGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNL 465 Query: 1480 IRSSGFEIKKFKFLPNDKKMALLELNSVEDAIHVLIDFHNHKLSEKNHLRISFSKA 1647 +G +K FKF D+KMAL++L SVE+AI LI+ HNH L E +HLR+SFSK+ Sbjct: 466 FTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKS 521
>sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1) Length = 521 Score = 341 bits (875), Expect = 3e-93 Identities = 208/531 (39%), Positives = 292/531 (54%), Gaps = 9/531 (1%) Frame = +1 Query: 82 NSHKKVKMDQGNDNKPSRVIHIRNVPQEVDDTAVAMLAVPFGYIDNIVFVRKNNQALIQM 261 N KK K D+ + PSRV+H+R +P +V + + L +PFG + N++ ++ +QA ++M Sbjct: 12 NDSKKFKRDRPPCS-PSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEM 70 Query: 262 REISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQLDLRN--NNSNIDKLVQHANEKRKHY 435 A+ M +Y+ P + + ++IQ+S H++L N N + +Q + + Sbjct: 71 ASEEAAVTMVNYYTPITPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGS 130 Query: 436 LV--NWSNNTG----GASEILRILIDNAPNLVINHLVFYKIFSRFGQIIRIVSFTKNNQH 597 L +N G G S +LRI+I+N V V ++IFS+FG +++I++FTKNNQ Sbjct: 131 LALSGGPSNEGTVLPGQSPVLRIIIENLFYPVTLE-VLHQIFSKFGTVLKIITFTKNNQF 189 Query: 598 HGLVEFVNPLAAHVAQLQLNGANLLGDCGTMRIDFSKNPGPLQVQRQSDKVRDYLESPLT 777 L+++ +P+ AH A++ L+G N+ C T+RIDFSK L V+ +DK RD+ L Sbjct: 190 QALLQYADPVNAHYAKMALDGQNIYNACCTLRIDFSKLTS-LNVKYNNDKSRDFTRLDLP 248 Query: 778 RNEMQELEGPQYGFPLFAVGRSPSMSRGNEQFMTAQLSAMASQTGVELTPXXXXXXXXXX 957 + Q P A G S G F A A+ V P Sbjct: 249 TGDGQPSLEPPMAAAFGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTIT- 307 Query: 958 XXCNQMNHRSTDQSNWGFGSNQTQSSMFSSNTGIDSGNSVVLVTNLNAEKSNPDALFTLF 1137 S T +GI GNSV+LVTNLN + P LF LF Sbjct: 308 ------------------SSAVTGRMAIPGASGI-PGNSVLLVTNLNPDLITPHGLFILF 348 Query: 1138 GVYGDVMRVKVMFNKKNTALVQFANHQQAMTAIRNLDACFLWGKQMHLHVSKTNVIQLPM 1317 GVYGDV RVK+MFNKK ALVQ A+ QA A+ +L L+GK + +SK +QLP Sbjct: 349 GVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPR 408 Query: 1318 E-DANHGLTKDYSNSTLHRFKKPNSKNYQNIFPPSAVLHLSNIPPTTGEGDLSEMIRSSG 1494 E + GLTKD+SNS LHRFKKP SKN+QNIFPPSA LHLSNIPP+ DL + +G Sbjct: 409 EGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTVDDLKNLFIEAG 468 Query: 1495 FEIKKFKFLPNDKKMALLELNSVEDAIHVLIDFHNHKLSEKNHLRISFSKA 1647 +K FKF D+KMAL++L SVE+AI LI+ HNH L E +HLR+SFSK+ Sbjct: 469 CSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKS 519
Score = 31.6 bits (70), Expect = 7.3
Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 3/102 (2%)
Frame = +1
Query: 58 DFSQNSFDNSHKKVKMDQGNDNKPSRVIHIRNVPQEVDDTAVAMLAVPFG-YIDNIVFVR 234
DFS + K + N PS +H+ N+P V + L + G + F +
Sbjct: 419 DFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQ 478
Query: 235 KNNQ-ALIQMREISEAID-MADYFNQCVPLMYGKHLFIQFSK 354
K+ + ALIQ+ + EAI + + N L HL + FSK
Sbjct: 479 KDRKMALIQLGSVEEAIQALIELHNH--DLGENHHLRVSFSK 518
>sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I) (57 kDa RNA-binding protein PPTB-1) Length = 531 Score = 339 bits (870), Expect = 1e-92 Identities = 205/534 (38%), Positives = 290/534 (54%), Gaps = 12/534 (2%) Frame = +1 Query: 82 NSHKKVKMDQGNDNKPSRVIHIRNVPQEVDDTAVAMLAVPFGYIDNIVFVRKNNQALIQM 261 N KK K D + PSRVIHIR +P +V + V L +PFG + N++ ++ NQA I+M Sbjct: 42 NDSKKFKGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEM 101 Query: 262 REISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQL--DLRNNNSNIDKLVQHANEKRKHY 435 A M +Y+ P++ G+ ++IQFS H++L D N + +Q N + Sbjct: 102 NTEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGN 161 Query: 436 L--------VNWSNNTGGASEILRILIDNAPNLVINHLVFYKIFSRFGQIIRIVSFTKNN 591 L V+ G S +LRI+++N + V ++IFS+FG +++I++FTKNN Sbjct: 162 LALAASAAAVDAGMAMAGQSPVLRIIVENL-FYPVTLDVLHQIFSKFGTVLKIITFTKNN 220 Query: 592 QHHGLVEFVNPLAAHVAQLQLNGANLLGDCGTMRIDFSKNPGPLQVQRQSDKVRDYLESP 771 Q L+++ +P++A A+L L+G N+ C T+RIDFSK L V+ +DK RDY Sbjct: 221 QFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTS-LNVKYNNDKSRDYTRPD 279 Query: 772 LTRNEMQELEGPQYGFPLFAVGRSPSMSRGNEQFMTAQLSAMASQTGVELTPXXXXXXXX 951 L + Q PS+ +Q M A L P Sbjct: 280 LPSGDSQ-----------------PSL----DQTMAAAFGLSVPNVHGALAPLAIPSAAA 318 Query: 952 XXXXCNQMNHRSTDQSNWGFGSNQTQSSMFSSNTGIDSGNSVVL-VTNLNAEKSNPDALF 1128 ++ + G+ + VL V+NLN E+ P +LF Sbjct: 319 AAAAAGRI-----------------------AIPGLAGAGNSVLLVSNLNPERVTPQSLF 355 Query: 1129 TLFGVYGDVMRVKVMFNKKNTALVQFANHQQAMTAIRNLDACFLWGKQMHLHVSKTNVIQ 1308 LFGVYGDV RVK++FNKK ALVQ A+ QA A+ +L+ L GK + + +SK +Q Sbjct: 356 ILFGVYGDVQRVKILFNKKENALVQMADGNQAQLAMSHLNGHKLHGKPIRITLSKHQNVQ 415 Query: 1309 LPME-DANHGLTKDYSNSTLHRFKKPNSKNYQNIFPPSAVLHLSNIPPTTGEGDLSEMIR 1485 LP E + GLTKDY NS LHRFKKP SKN+QNIFPPSA LHLSNIPP+ E DL + Sbjct: 416 LpreGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEEDLKVLFS 475 Query: 1486 SSGFEIKKFKFLPNDKKMALLELNSVEDAIHVLIDFHNHKLSEKNHLRISFSKA 1647 S+G +K FKF D+KMAL+++ SVE+A+ LID HNH L E +HLR+SFSK+ Sbjct: 476 SNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIDLHNHDLGENHHLRVSFSKS 529
>sp|P17225|PTBP1_MOUSE Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I) Length = 527 Score = 316 bits (810), Expect = 1e-85 Identities = 197/532 (37%), Positives = 277/532 (52%), Gaps = 10/532 (1%) Frame = +1 Query: 82 NSHKKVKMDQGNDNKPSRVIHIRNVPQEVDDTAVAMLAVPFGYIDNIVFVRKNNQALIQM 261 N KK K D + PSRVIH+R +P +V + V L +PFG + N++ ++ NQA I+M Sbjct: 41 NDSKKFKGDNRSAGVPSRVIHVRKLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEM 100 Query: 262 REISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQL--DLRNNNSNIDKLVQHANEKRKHY 435 A M +Y+ P++ G+ ++IQFS H++L D N +Q N + Sbjct: 101 NTEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKELKTDSSPNQVRAQAALQAVNSVQSGN 160 Query: 436 L--------VNWSNNTGGASEILRILIDNAPNLVINHLVFYKIFSRFGQIIRIVSFTKNN 591 L V+ G S +LRI+++N V V ++IFS+FG +++I++FTKNN Sbjct: 161 LALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLD-VLHQIFSKFGTVLKIITFTKNN 219 Query: 592 QHHGLVEFVNPLAAHVAQLQLNGANLLGDCGTMRIDFSKNPGPLQVQRQSDKVRDYLESP 771 Q L+++ +P++A A+L L+G N+ C T+RIDFSK L V+ +DK RDY Sbjct: 220 QFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTS-LNVKYNNDKSRDYTRPD 278 Query: 772 LTRNEMQELEGPQYGFPLFAVGRSPSMSRGNEQFMTAQLSAMASQTGVELTPXXXXXXXX 951 L + Q PS+ +Q M A L P Sbjct: 279 LPSGDSQ-----------------PSL----DQTMAAAFGLSVPNVHGALAPLAIPS--- 314 Query: 952 XXXXCNQMNHRSTDQSNWGFGSNQTQSSMFSSNTGIDSGNSVVLVTNLNAEKSNPDALFT 1131 + +S + +GNSV+LV+NLN E+ P +LF Sbjct: 315 --------------------AAAAAAASRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFI 354 Query: 1132 LFGVYGDVMRVKVMFNKKNTALVQFANHQQAMTAIRNLDACFLWGKQMHLHVSKTNVIQL 1311 LFGVYGDV RVK++FNKK ALVQ A+ QA A H V + Sbjct: 355 LFGVYGDVQRVKILFNKKENALVQMADGSQAQLGEPPERAQAAREVSAHYTVQASECAAA 414 Query: 1312 PMEDANHGLTKDYSNSTLHRFKKPNSKNYQNIFPPSAVLHLSNIPPTTGEGDLSEMIRSS 1491 + GLTKDY +S L RFKKP SKN+QNIFPPSA LHLSNIPP+ E DL + S+ Sbjct: 415 REGQEDQGLTKDYGSSPL-RFKKPGSKNFQNIFPPSATLHLSNIPPSVSEDDLKSLFSSN 473 Query: 1492 GFEIKKFKFLPNDKKMALLELNSVEDAIHVLIDFHNHKLSEKNHLRISFSKA 1647 G +K FKF D+KMAL+++ SVE+A+ LI+ HNH L E +HLR+SFSK+ Sbjct: 474 GGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGENHHLRVSFSKS 525
>sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprotein L-like (Stromal RNA-regulating factor) (BLOCK24 protein) Length = 542 Score = 119 bits (299), Expect = 2e-26 Identities = 129/529 (24%), Positives = 223/529 (42%), Gaps = 9/529 (1%) Frame = +1 Query: 61 FSQNSFDNSHKKVKMDQGNDNKPSRVIHIRNVPQEVDDTAVAMLAVPFGYIDNIVFVRKN 240 FSQ SH KV + S V+H+R + + V + + FG I ++ + Sbjct: 60 FSQPEAGGSHHKVSV--------SPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFK 111 Query: 241 NQALIQMREISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQLDLRNNNSNIDKLVQHANE 420 QAL++ I A + + + G+ F +S +++ N Sbjct: 112 RQALVEFENIDSAKECVTFAADEPVYIAGQQAFFNYSTSKRITRPGN------------- 158 Query: 421 KRKHYLVNWSNNTGGASEILRILIDNAPNLVINHLVFYKIFSRFGQIIRIVSFTKNNQHH 600 +++ G +++L + I N P I V Y + + G++ RIV F K N Sbjct: 159 ---------TDDPSGGNKVLLLSIQN-PLYPITVDVLYTVCNPVGKVQRIVIF-KRNGIQ 207 Query: 601 GLVEFVNPLAAHVAQLQLNGANLLGDCGTMRIDFSKNPGPLQVQRQSDKVRDYLESPLTR 780 +VEF + L A A+ LNGA++ C T++I++++ P L V R + DY + L R Sbjct: 208 AMVEFESVLCAQKAKAALNGADIYAGCCTLKIEYAR-PTRLNVIRNDNDSWDYTKPYLGR 266 Query: 781 NEMQELEGPQYGFPLFAVGRSPSMSRGNEQFMTAQLSAMASQTGVELTPXXXXXXXXXXX 960 + + Q +G PS R + L + S+ Sbjct: 267 RDRGKGRQRQA-----ILGEHPSSFRHDGYGSHGPLLPLPSRY----------------- 304 Query: 961 XCNQMNHRSTDQSNWGFGSNQTQSSMFSSNTGIDSGNSVVLVTNLNAEKSNPDALFTLFG 1140 +M R T + + Q SS G + SVV+V+ L+ K N +F LF Sbjct: 305 ---RMGSRDTPELV-AYPLPQASSSYMH---GGNPSGSVVMVSGLHQLKMNCSRVFNLFC 357 Query: 1141 VYGDVMRVKVMFNKKNTALVQFANHQQAMTAIRNLDACFLWGKQMHLHVSKTNVIQ---- 1308 +YG++ +VK M TALV+ + A+ +L+ L+GK++++ VSK + + Sbjct: 358 LYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHSVVPSQI 417 Query: 1309 LPMEDANHGLTKDYSNSTLHRFKKPNSKNYQNIFPPSAVLHLSNIPPTTGEGDLSEMIRS 1488 +ED KD++ S +RF + I PPS VLH N+P E +++ Sbjct: 418 FELEDGTSSY-KDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCND 476 Query: 1489 ----SGFEIKKFKFLPNDKKMA-LLELNSVEDAIHVLIDFHNHKLSEKN 1620 + + K F P+ K ++ LLE DA+ L +++++ N Sbjct: 477 HEVLTFIKYKVFDAKPSAKTLSGLLEWECKTDAVEALTALNHYQIRVPN 525
>sp|Q921F4|HNRLL_MOUSE Heterogeneous nuclear ribonucleoprotein L-like Length = 591 Score = 113 bits (282), Expect = 2e-24 Identities = 128/523 (24%), Positives = 221/523 (42%), Gaps = 11/523 (2%) Frame = +1 Query: 85 SHKKVKMDQGNDNKPSRVIHIRNVPQEVDDTAVAMLAVPFGYIDNIVFVRKNNQALIQMR 264 SH KV + S V+H+R + + V + + FG I ++ + QAL++ Sbjct: 117 SHHKVSV--------SPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFE 168 Query: 265 EISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQLDLRNNNSNIDKLVQHANEKRKHYLVN 444 I A + + + G+ F +S +++ N Sbjct: 169 NIDSAKECVTFAADVPVYIAGQQAFFNYSTSKRITRPGN--------------------- 207 Query: 445 WSNNTGGASEILRILIDNAPNLVINHLVFYKIFSRFGQIIRIVSFTKNNQHHGLVEFVNP 624 +++ G +++L + I N P I V Y + + G++ RIV F K N +VEF + Sbjct: 208 -TDDPSGGNKVLLLSIQN-PLYPITVDVLYTVCNPVGKVQRIVIF-KRNGIQAMVEFESV 264 Query: 625 LAAHVAQLQLNGANLLGDCGTMRIDFSKNPGPLQVQRQSDKVRDYLESPLTRNEMQELEG 804 L A A+ LNGA++ C T++I++++ P L V R + DY + L R + + Sbjct: 265 LCAQKAKAALNGADIYAGCCTLKIEYAR-PTRLNVIRNDNDSWDYTKPYLGRRDRGKGRQ 323 Query: 805 PQYGFPLFAVGRSPSMSRGNEQFMTAQLSAMASQTGVELTPXXXXXXXXXXXXCNQMNHR 984 Q +G PS R + L + S+ +M R Sbjct: 324 RQA-----ILGDHPSSFRHDGYGSHGPLLPLPSRY--------------------RMGSR 358 Query: 985 STDQSNWGFGSNQTQSSMFSSNTGIDSGNSVVLVTNLNAEKSNPDALFTLFGVYGDVMRV 1164 T + Q+S + G SG SVV+V+ L+ K N +F LF +YG++ +V Sbjct: 359 DTPEL---VAYPLPQASSSYMHGGSPSG-SVVMVSGLHQLKMNCSRVFNLFCLYGNIEKV 414 Query: 1165 KVMFNKKNTALVQFANHQQAMTAIRNLDACFLWGKQMHLHVSKTNVIQ----LPMEDANH 1332 K M TALV+ + A+ +L+ L+GK++++ VSK + + +ED Sbjct: 415 KFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHSVVPSQIFELEDGTS 474 Query: 1333 GLTKDYSNSTLHRFKKPNSKNYQNIFPPSAVLHLSNIPPTTGEGDLSEMIRSSGFEIKKF 1512 KD++ S +RF + I PPS VLH N+P E +++ + E+ F Sbjct: 475 SY-KDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKL--CNDHEVLPF 531 Query: 1513 -KFLPNDKKMA------LLELNSVEDAIHVLIDFHNHKLSEKN 1620 K+ D K + LLE DA+ L +++++ N Sbjct: 532 IKYKVFDAKASAKTLSGLLEWKCKTDAVEALTALNHYQIRVPN 574
>sp|Q8R081|HNRPL_MOUSE Heterogeneous nuclear ribonucleoprotein L (hnRNP L) Length = 555 Score = 81.6 bits (200), Expect = 6e-15 Identities = 64/213 (30%), Positives = 103/213 (48%), Gaps = 15/213 (7%) Frame = +1 Query: 1054 GIDSGNSVVLVTNLNAEKSNPDALFTLFGVYGDVMRVKVMFNKKNTALVQFANHQQAMTA 1233 G + + V++V L+ K N D +F +F +YG+V +VK M +K A+V+ A+ A Sbjct: 342 GPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRA 401 Query: 1234 IRNLDACFLWGKQMHLHVSKTNVIQLPMEDANHGLT------KDYSNSTLHRFKKPNSKN 1395 I +L+ F++G++M++ VSK I M ++GL KD+S S +RF P Sbjct: 402 ITHLNNNFMFGQKMNVCVSKQPAI---MPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAA 458 Query: 1396 YQNIFPPSAVLHLSNIPPTTGEGDLSEMIRSSGFE----IKKFKFLPNDKKMALLELNSV 1563 I PS VLH N P E + E+ G + +K F LLE +S Sbjct: 459 KNRIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPTSVKVFSGKSERSSSGLLEWDSK 518 Query: 1564 EDAIHVLIDFHNHKLSEKN-----HLRISFSKA 1647 DA+ L +++++ N L++ FS A Sbjct: 519 SDALETLGFLNHYQMKNPNGPYPYTLKLCFSTA 551
Score = 62.4 bits (150), Expect = 4e-09
Identities = 56/224 (25%), Positives = 95/224 (42%)
Frame = +1
Query: 106 DQGNDNKPSRVIHIRNVPQEVDDTAVAMLAVPFGYIDNIVFVRKNNQALIQMREISEAID 285
D + S V+HIR + V + + FG I +V + K QAL++ ++ A +
Sbjct: 59 DDPHKTPASPVVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACN 118
Query: 286 MADYFNQCVPLMYGKHLFIQFSKHQQLDLRNNNSNIDKLVQHANEKRKHYLVNWSNNTGG 465
+Y + G F+ +S Q++ + S+++
Sbjct: 119 AVNYAADNQIYIAGHPAFVNYSTSQKISRPGD----------------------SDDSRS 156
Query: 466 ASEILRILIDNAPNLVINHLVFYKIFSRFGQIIRIVSFTKNNQHHGLVEFVNPLAAHVAQ 645
+ +L I N P I V Y I + G + RIV F KN +VEF + +A A+
Sbjct: 157 VNSVLLFTILN-PIYSITTDVLYTICNPCGPVQRIVIFRKNGV-QAMVEFDSVQSAQRAK 214
Query: 646 LQLNGANLLGDCGTMRIDFSKNPGPLQVQRQSDKVRDYLESPLT 777
LNGA++ C T++I+++K P L V + DY L+
Sbjct: 215 ASLNGADIYSGCCTLKIEYAK-PTRLNVFKNDQDTWDYTNPNLS 257
Score = 35.4 bits (80), Expect = 0.51
Identities = 42/159 (26%), Positives = 66/159 (41%), Gaps = 8/159 (5%)
Frame = +1
Query: 964 CNQMNHRSTDQ----SNWGFGSNQTQSSMFSSNTGIDSG--NSVVLVTNLNAEKS-NPDA 1122
CN +N+ + +Q + F + T + DS NSV+L T LN S D
Sbjct: 117 CNAVNYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSRSVNSVLLFTILNPIYSITTDV 176
Query: 1123 LFTLFGVYGDVMRVKVMFNKKNTALVQFANHQQAMTAIRNLDACFLWGKQMHLHVSKTNV 1302
L+T+ G V R+ + A+V+F + Q A A +L+ ++ L +
Sbjct: 177 LYTICNPCGPVQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKP 236
Query: 1303 IQLPMEDANHGLTKDYSNSTLHRFKKPNSK-NYQNIFPP 1416
+L + N T DY+N L P S N + PP
Sbjct: 237 TRLNV-FKNDQDTWDYTNPNLSGQGDPGSNPNKRQRQPP 274
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 193,718,428
Number of Sequences: 369166
Number of extensions: 4086817
Number of successful extensions: 10449
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 9664
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10420
length of database: 68,354,980
effective HSP length: 116
effective length of database: 46,925,720
effective search space used: 21116574000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Cluster detail
