Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_G12
(624 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein ... 197 1e-50
sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1) 197 2e-50
sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1) 197 2e-50
sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1) 196 4e-50
sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 ... 195 9e-50
sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 ... 193 3e-49
sp|P17225|PTBP1_MOUSE Polypyrimidine tract-binding protein ... 166 4e-41
sp|Q8R081|HNRPL_MOUSE Heterogeneous nuclear ribonucleoprote... 67 3e-11
sp|P14866|HNRPL_HUMAN Heterogeneous nuclear ribonucleoprote... 65 1e-10
sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprote... 62 2e-09
>sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I) (57 kDa RNA-binding
protein PPTB-1)
Length = 531
Score = 197 bits (502), Expect = 1e-50
Identities = 98/171 (57%), Positives = 123/171 (71%), Gaps = 1/171 (0%)
Frame = +2
Query: 62 GVYGDVMRVKVMFNKKNTALVQFANHQQAMTAIRNLDACFLWGKQMHLHVSKTNVIQLPM 241
GVYGDV RVK++FNKK ALVQ A+ QA A+ +L+ L GK + + +SK +QLP
Sbjct: 359 GVYGDVQRVKILFNKKENALVQMADGNQAQLAMSHLNGHKLHGKPIRITLSKHQNVQLPR 418
Query: 242 E-DANHGLTKDYSNSTLHRFKKPNSKNYQNIFPPSAVLHLSNIPPTTGEGDLSEMIRSSG 418
E + GLTKDY NS LHRFKKP SKN+QNIFPPSA LHLSNIPP+ E DL + S+G
Sbjct: 419 EGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEEDLKVLFSSNG 478
Query: 419 FEIKKFKFLPNDKKMALLELNSVEDAIHVLIDFHNHKLSEKNHLRISFSKA 571
+K FKF D+KMAL+++ SVE+A+ LID HNH L E +HLR+SFSK+
Sbjct: 479 GVVKGFKFFQKDRKMALIQMGSVEEAVQALIDLHNHDLGENHHLRVSFSKS 529
>sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1)
Length = 523
Score = 197 bits (500), Expect = 2e-50
Identities = 98/171 (57%), Positives = 121/171 (70%), Gaps = 1/171 (0%)
Frame = +2
Query: 62 GVYGDVMRVKVMFNKKNTALVQFANHQQAMTAIRNLDACFLWGKQMHLHVSKTNVIQLPM 241
GVYGDV RVK+MFNKK ALVQ A+ QA A+ +L L+GK + +SK +QLP
Sbjct: 351 GVYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPR 410
Query: 242 E-DANHGLTKDYSNSTLHRFKKPNSKNYQNIFPPSAVLHLSNIPPTTGEGDLSEMIRSSG 418
E + GLTKD+SNS LHRFKKP SKN+QNIFPPSA LHLSNIPP+ DL + +G
Sbjct: 411 EGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAG 470
Query: 419 FEIKKFKFLPNDKKMALLELNSVEDAIHVLIDFHNHKLSEKNHLRISFSKA 571
+K FKF D+KMAL++L SVE+AI LI+ HNH L E +HLR+SFSK+
Sbjct: 471 CSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKS 521
>sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1)
Length = 523
Score = 197 bits (500), Expect = 2e-50
Identities = 98/171 (57%), Positives = 121/171 (70%), Gaps = 1/171 (0%)
Frame = +2
Query: 62 GVYGDVMRVKVMFNKKNTALVQFANHQQAMTAIRNLDACFLWGKQMHLHVSKTNVIQLPM 241
GVYGDV RVK+MFNKK ALVQ A+ QA A+ +L L+GK + +SK +QLP
Sbjct: 351 GVYGDVHRVKIMFNKKENALVQMADASQAQIAMNHLSGQRLYGKVLRATLSKHQAVQLPR 410
Query: 242 E-DANHGLTKDYSNSTLHRFKKPNSKNYQNIFPPSAVLHLSNIPPTTGEGDLSEMIRSSG 418
E + GLTKD+SNS LHRFKKP SKN+QNIFPPSA LHLSNIPP+ DL + +G
Sbjct: 411 EGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAG 470
Query: 419 FEIKKFKFLPNDKKMALLELNSVEDAIHVLIDFHNHKLSEKNHLRISFSKA 571
+K FKF D+KMAL++L SVE+AI LI+ HNH L E +HLR+SFSK+
Sbjct: 471 CSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKS 521
>sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1)
Length = 521
Score = 196 bits (498), Expect = 4e-50
Identities = 98/171 (57%), Positives = 121/171 (70%), Gaps = 1/171 (0%)
Frame = +2
Query: 62 GVYGDVMRVKVMFNKKNTALVQFANHQQAMTAIRNLDACFLWGKQMHLHVSKTNVIQLPM 241
GVYGDV RVK+MFNKK ALVQ A+ QA A+ +L L+GK + +SK +QLP
Sbjct: 349 GVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPR 408
Query: 242 E-DANHGLTKDYSNSTLHRFKKPNSKNYQNIFPPSAVLHLSNIPPTTGEGDLSEMIRSSG 418
E + GLTKD+SNS LHRFKKP SKN+QNIFPPSA LHLSNIPP+ DL + +G
Sbjct: 409 EGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTVDDLKNLFIEAG 468
Query: 419 FEIKKFKFLPNDKKMALLELNSVEDAIHVLIDFHNHKLSEKNHLRISFSKA 571
+K FKF D+KMAL++L SVE+AI LI+ HNH L E +HLR+SFSK+
Sbjct: 469 CSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKS 519
>sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I) (Pyrimidine-binding
protein) (PYBP)
Length = 555
Score = 195 bits (495), Expect = 9e-50
Identities = 95/171 (55%), Positives = 123/171 (71%), Gaps = 1/171 (0%)
Frame = +2
Query: 62 GVYGDVMRVKVMFNKKNTALVQFANHQQAMTAIRNLDACFLWGKQMHLHVSKTNVIQLPM 241
GVYGDV RVK++FNKK ALV+ A+ QA A+ +L+ L GK + + +SK +QLP
Sbjct: 383 GVYGDVQRVKILFNKKENALVEMADGSQAQLAMSHLNGHKLHGKSVRITLSKHQSVQLPR 442
Query: 242 E-DANHGLTKDYSNSTLHRFKKPNSKNYQNIFPPSAVLHLSNIPPTTGEGDLSEMIRSSG 418
E + GLTKDY +S LHRFKKP SKN+QNIFPPSA LHLSNIPP+ E DL + S+G
Sbjct: 443 EGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEDDLKSLFSSNG 502
Query: 419 FEIKKFKFLPNDKKMALLELNSVEDAIHVLIDFHNHKLSEKNHLRISFSKA 571
+K FKF D+KMAL+++ SVE+A+ LI+ HNH L E +HLR+SFSK+
Sbjct: 503 GVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGENHHLRVSFSKS 553
>sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I)
Length = 557
Score = 193 bits (491), Expect = 3e-49
Identities = 98/171 (57%), Positives = 122/171 (71%), Gaps = 1/171 (0%)
Frame = +2
Query: 62 GVYGDVMRVKVMFNKKNTALVQFANHQQAMTAIRNLDACFLWGKQMHLHVSKTNVIQLPM 241
GVY DV RVK++FNKK ALVQ A+ QA A+ +L+ L GK + + +SK +QLP
Sbjct: 385 GVYCDVQRVKILFNKKENALVQMADGSQAQLAMSHLNGHKLHGKPVRITLSKHQNVQLPR 444
Query: 242 E-DANHGLTKDYSNSTLHRFKKPNSKNYQNIFPPSAVLHLSNIPPTTGEGDLSEMIRSSG 418
E + GLTKDY NS LHRFKKP SKN+QNIFPPSA LHLSNIPP+ E DL + S+G
Sbjct: 445 EGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSISEEDLKILFSSNG 504
Query: 419 FEIKKFKFLPNDKKMALLELNSVEDAIHVLIDFHNHKLSEKNHLRISFSKA 571
+K FKF D+KMAL+++ SVE+AI LID HNH L E +HLR+SFSK+
Sbjct: 505 GIVKGFKFFQKDRKMALIQMGSVEEAIQALIDLHNHDLGENHHLRVSFSKS 555
>sp|P17225|PTBP1_MOUSE Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I)
Length = 527
Score = 166 bits (420), Expect = 4e-41
Identities = 87/170 (51%), Positives = 108/170 (63%)
Frame = +2
Query: 62 GVYGDVMRVKVMFNKKNTALVQFANHQQAMTAIRNLDACFLWGKQMHLHVSKTNVIQLPM 241
GVYGDV RVK++FNKK ALVQ A+ QA A H V +
Sbjct: 357 GVYGDVQRVKILFNKKENALVQMADGSQAQLGEPPERAQAAREVSAHYTVQASECAAARE 416
Query: 242 EDANHGLTKDYSNSTLHRFKKPNSKNYQNIFPPSAVLHLSNIPPTTGEGDLSEMIRSSGF 421
+ GLTKDY +S L RFKKP SKN+QNIFPPSA LHLSNIPP+ E DL + S+G
Sbjct: 417 GQEDQGLTKDYGSSPL-RFKKPGSKNFQNIFPPSATLHLSNIPPSVSEDDLKSLFSSNGG 475
Query: 422 EIKKFKFLPNDKKMALLELNSVEDAIHVLIDFHNHKLSEKNHLRISFSKA 571
+K FKF D+KMAL+++ SVE+A+ LI+ HNH L E +HLR+SFSK+
Sbjct: 476 VVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGENHHLRVSFSKS 525
>sp|Q8R081|HNRPL_MOUSE Heterogeneous nuclear ribonucleoprotein L (hnRNP L)
Length = 555
Score = 67.4 bits (163), Expect = 3e-11
Identities = 58/198 (29%), Positives = 92/198 (46%), Gaps = 16/198 (8%)
Frame = +2
Query: 26 QLSSTCNK-FKCGGVYGDVMRVKVMFNKKNTALVQFANHQQAMTAIRNLDACFLWGKQMH 202
Q C++ F +YG+V +VK M +K A+V+ A+ AI +L+ F++G++M+
Sbjct: 357 QSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKMN 416
Query: 203 LHVSKTNVIQLPMEDANHGLT------KDYSNSTLHRFKKPNSKNYQNIFPPSAVLHLSN 364
+ VSK I M ++GL KD+S S +RF P I PS VLH N
Sbjct: 417 VCVSKQPAI---MPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFN 473
Query: 365 IPPTTGEGDLSEMIRSSGFE----IKKFKFLPNDKKMALLELNSVEDAIHVLIDFHNHKL 532
P E + E+ G + +K F LLE +S DA+ L +++++
Sbjct: 474 APLEVTEENFFEICDELGVKRPTSVKVFSGKSERSSSGLLEWDSKSDALETLGFLNHYQM 533
Query: 533 SEKN-----HLRISFSKA 571
N L++ FS A
Sbjct: 534 KNPNGPYPYTLKLCFSTA 551
>sp|P14866|HNRPL_HUMAN Heterogeneous nuclear ribonucleoprotein L (hnRNP L)
Length = 558
Score = 65.5 bits (158), Expect = 1e-10
Identities = 54/184 (29%), Positives = 86/184 (46%), Gaps = 15/184 (8%)
Frame = +2
Query: 65 VYGDVMRVKVMFNKKNTALVQFANHQQAMTAIRNLDACFLWGKQMHLHVSKTNVIQLPME 244
+YG+V +VK M +K A+V+ A+ AI +L+ F++G+++++ VSK I M
Sbjct: 374 LYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKLNVCVSKQPAI---MP 430
Query: 245 DANHGLT------KDYSNSTLHRFKKPNSKNYQNIFPPSAVLHLSNIPPTTGEGDLSEMI 406
++GL KD+S S +RF P I PS VLH N P E + E+
Sbjct: 431 GQSYGLEDGSCSYKDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEIC 490
Query: 407 RSSGFE----IKKFKFLPNDKKMALLELNSVEDAIHVLIDFHNHKLSEKN-----HLRIS 559
G + +K F LLE S DA+ L +++++ N L++
Sbjct: 491 DELGVKRPSSVKVFSGKSERSSSGLLEWESKSDALETLGFLNHYQMKNPNGPYPYTLKLC 550
Query: 560 FSKA 571
FS A
Sbjct: 551 FSTA 554
>sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprotein L-like (Stromal
RNA-regulating factor) (BLOCK24 protein)
Length = 542
Score = 61.6 bits (148), Expect = 2e-09
Identities = 49/183 (26%), Positives = 87/183 (47%), Gaps = 10/183 (5%)
Frame = +2
Query: 26 QLSSTCNK-FKCGGVYGDVMRVKVMFNKKNTALVQFANHQQAMTAIRNLDACFLWGKQMH 202
QL C++ F +YG++ +VK M TALV+ + A+ +L+ L+GK+++
Sbjct: 344 QLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLN 403
Query: 203 LHVSKTNVIQ----LPMEDANHGLTKDYSNSTLHRFKKPNSKNYQNIFPPSAVLHLSNIP 370
+ VSK + + +ED KD++ S +RF + I PPS VLH N+P
Sbjct: 404 VCVSKQHSVVPSQIFELEDGTSSY-KDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVP 462
Query: 371 PTTGEGDLSEMIRS----SGFEIKKFKFLPNDKKMA-LLELNSVEDAIHVLIDFHNHKLS 535
E +++ + + K F P+ K ++ LLE DA+ L +++++
Sbjct: 463 LCVTEETFTKLCNDHEVLTFIKYKVFDAKPSAKTLSGLLEWECKTDAVEALTALNHYQIR 522
Query: 536 EKN 544
N
Sbjct: 523 VPN 525
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,958,937
Number of Sequences: 369166
Number of extensions: 1423335
Number of successful extensions: 3642
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3519
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3632
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 4926080070
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)