Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_020_P08
(848 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 ... 150 4e-36
sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 ... 150 4e-36
sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein ... 149 7e-36
sp|P17225|PTBP1_MOUSE Polypyrimidine tract-binding protein ... 149 1e-35
sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1) 139 1e-32
sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1) 136 6e-32
sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1) 136 8e-32
sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprote... 68 3e-11
sp|Q921F4|HNRLL_MOUSE Heterogeneous nuclear ribonucleoprote... 65 2e-10
sp|Q8R081|HNRPL_MOUSE Heterogeneous nuclear ribonucleoprote... 62 2e-09
>sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I)
Length = 557
Score = 150 bits (379), Expect = 4e-36
Identities = 87/247 (35%), Positives = 137/247 (55%), Gaps = 10/247 (4%)
Frame = +1
Query: 82 NSHKKVKMDQGNDNKPSRVIHIRNVPQEVDDTAVAMLAVPFGYIDNIVFVRKNNQALIQM 261
N KK K D + PSRVIHIR +P +V + V L +PFG + N++ ++ NQA I+M
Sbjct: 42 NDSKKFKGDNRSAGVPSRVIHIRKLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEM 101
Query: 262 REISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQL--DLRNNNSNIDKLVQHANEKRKHY 435
A M +Y+ P++ G+ ++IQFS H++L D N + +Q N +
Sbjct: 102 NTEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGN 161
Query: 436 L--------VNWSNNTGGASEILRILIDNAPNLVINHLVFYKIFSRFGQIIRIVSFTKNN 591
L V+ G S +LRI+++N + V ++IFS+FG +++I++FTKNN
Sbjct: 162 LALAASAAAVDAGMAMAGQSPVLRIIVENL-FYPVTLDVLHQIFSKFGTVLKIITFTKNN 220
Query: 592 QHHGLVEFVNPLAAHVAQLQLNGANLLGDCGTMRIDFSKNPGPLQVQRQSDKVRDYLESP 771
Q L+++ +P++A A+L L+G N+ C T+RIDFSK L V+ +DK RDY
Sbjct: 221 QFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTS-LNVKYNNDKSRDYTRPD 279
Query: 772 LTRNEMQ 792
L + Q
Sbjct: 280 LPSGDNQ 286
Score = 34.3 bits (77), Expect = 0.45
Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Frame = +1
Query: 127 PSRVIHIRNVPQEVDDTAVAML-AVPFGYIDNIVFVRKNNQ-ALIQMREISEAID-MADY 297
PS +H+ N+P + + + +L + G + F +K+ + ALIQM + EAI + D
Sbjct: 478 PSATLHLSNIPPSISEEDLKILFSSNGGIVKGFKFFQKDRKMALIQMGSVEEAIQALIDL 537
Query: 298 FNQCVPLMYGKHLFIQFSK 354
N L HL + FSK
Sbjct: 538 HNH--DLGENHHLRVSFSK 554
Score = 31.2 bits (69), Expect = 3.8
Identities = 42/166 (25%), Positives = 73/166 (43%), Gaps = 2/166 (1%)
Frame = +1
Query: 220 IVFVRKNNQALIQMREISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQLDLRNNNSNIDK 399
I+F +K N AL+QM + S+A + N ++GK + I SKHQ + L
Sbjct: 395 ILFNKKEN-ALVQMADGSQAQLAMSHLNG--HKLHGKPVRITLSKHQNVQLpreGQEDQG 451
Query: 400 LVQ-HANEKRKHYLVNWSNNTGGASEILRIL-IDNAPNLVINHLVFYKIFSRFGQIIRIV 573
L + + N + S N L + N P I+ +FS G I++
Sbjct: 452 LTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPP-SISEEDLKILFSSNGGIVKGF 510
Query: 574 SFTKNNQHHGLVEFVNPLAAHVAQLQLNGANLLGDCGTMRIDFSKN 711
F + ++ L++ + A A + L+ + LG+ +R+ FSK+
Sbjct: 511 KFFQKDRKMALIQMGSVEEAIQALIDLHNHD-LGENHHLRVSFSKS 555
>sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I) (Pyrimidine-binding
protein) (PYBP)
Length = 555
Score = 150 bits (379), Expect = 4e-36
Identities = 86/247 (34%), Positives = 137/247 (55%), Gaps = 10/247 (4%)
Frame = +1
Query: 82 NSHKKVKMDQGNDNKPSRVIHIRNVPQEVDDTAVAMLAVPFGYIDNIVFVRKNNQALIQM 261
N KK K D + PSRVIH+R +P +V + V L +PFG + N++ ++ NQA I+M
Sbjct: 41 NDSKKFKGDNRSTGVPSRVIHVRKLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEM 100
Query: 262 REISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQL--DLRNNNSNIDKLVQHANEKRKHY 435
A M +Y+ P++ G+ ++IQFS H++L D N + +Q N +
Sbjct: 101 STEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGN 160
Query: 436 L--------VNWSNNTGGASEILRILIDNAPNLVINHLVFYKIFSRFGQIIRIVSFTKNN 591
L V+ G S +LRI+++N + V ++IFS+FG +++I++FTKNN
Sbjct: 161 LALAASAAAVDAGMAMAGQSPVLRIIVENL-FYPVTLDVLHQIFSKFGTVLKIITFTKNN 219
Query: 592 QHHGLVEFVNPLAAHVAQLQLNGANLLGDCGTMRIDFSKNPGPLQVQRQSDKVRDYLESP 771
Q L+++ +P++A A+L L+G N+ C T+RIDFSK L V+ +DK RDY
Sbjct: 220 QFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTS-LNVKYNNDKSRDYTRPD 278
Query: 772 LTRNEMQ 792
L + Q
Sbjct: 279 LPSGDSQ 285
Score = 35.8 bits (81), Expect = 0.15
Identities = 35/123 (28%), Positives = 54/123 (43%), Gaps = 3/123 (2%)
Frame = +1
Query: 463 GASEILRILIDNAPNLVINHLVFYKIFSRFGQIIRIVSFTKNNQHHGLVEFVNPLAAHVA 642
GA + ++ + P V +F +F +G + R V N + + LVE + A +A
Sbjct: 357 GAGNSVLLVSNLNPERVTPQSLFI-LFGVYGDVQR-VKILFNKKENALVEMADGSQAQLA 414
Query: 643 QLQLNGANLLGDCGTMRIDFSKNPG---PLQVQRQSDKVRDYLESPLTRNEMQELEGPQY 813
LNG L G ++RI SK+ P + Q +DY SPL R + + Q
Sbjct: 415 MSHLNGHKLHGK--SVRITLSKHQSVQLpreGQEDQGLTKDYGSSPLHRFKKPGSKNFQN 472
Query: 814 GFP 822
FP
Sbjct: 473 IFP 475
Score = 33.9 bits (76), Expect = 0.58
Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Frame = +1
Query: 127 PSRVIHIRNVPQEV-DDTAVAMLAVPFGYIDNIVFVRKNNQ-ALIQMREISEAID-MADY 297
PS +H+ N+P V +D ++ + G + F +K+ + ALIQM + EA+ + +
Sbjct: 476 PSATLHLSNIPPSVSEDDLKSLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIEL 535
Query: 298 FNQCVPLMYGKHLFIQFSK 354
N L HL + FSK
Sbjct: 536 HNH--DLGENHHLRVSFSK 552
Score = 32.7 bits (73), Expect = 1.3
Identities = 40/191 (20%), Positives = 82/191 (42%), Gaps = 6/191 (3%)
Frame = +1
Query: 157 PQEVDDTAVAMLAVPFGYIDNI-VFVRKNNQALIQMREISEAIDMADYFNQCVPLMYGKH 333
P+ V ++ +L +G + + + K AL++M + S+A + N ++GK
Sbjct: 370 PERVTPQSLFILFGVYGDVQRVKILFNKKENALVEMADGSQAQLAMSHLNG--HKLHGKS 427
Query: 334 LFIQFSKHQQLDLRNNNSNIDKLVQHANEKRKHYL-----VNWSNNTGGASEILRILIDN 498
+ I SKHQ + L L + H N+ N ++ + + N
Sbjct: 428 VRITLSKHQSVQLpreGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSA---TLHLSN 484
Query: 499 APNLVINHLVFYKIFSRFGQIIRIVSFTKNNQHHGLVEFVNPLAAHVAQLQLNGANLLGD 678
P V + +FS G +++ F + ++ L++ + A A ++L+ + LG+
Sbjct: 485 IPPSV-SEDDLKSLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHD-LGE 542
Query: 679 CGTMRIDFSKN 711
+R+ FSK+
Sbjct: 543 NHHLRVSFSKS 553
>sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I) (57 kDa RNA-binding
protein PPTB-1)
Length = 531
Score = 149 bits (377), Expect = 7e-36
Identities = 87/247 (35%), Positives = 137/247 (55%), Gaps = 10/247 (4%)
Frame = +1
Query: 82 NSHKKVKMDQGNDNKPSRVIHIRNVPQEVDDTAVAMLAVPFGYIDNIVFVRKNNQALIQM 261
N KK K D + PSRVIHIR +P +V + V L +PFG + N++ ++ NQA I+M
Sbjct: 42 NDSKKFKGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEM 101
Query: 262 REISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQL--DLRNNNSNIDKLVQHANEKRKHY 435
A M +Y+ P++ G+ ++IQFS H++L D N + +Q N +
Sbjct: 102 NTEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGN 161
Query: 436 L--------VNWSNNTGGASEILRILIDNAPNLVINHLVFYKIFSRFGQIIRIVSFTKNN 591
L V+ G S +LRI+++N + V ++IFS+FG +++I++FTKNN
Sbjct: 162 LALAASAAAVDAGMAMAGQSPVLRIIVENL-FYPVTLDVLHQIFSKFGTVLKIITFTKNN 220
Query: 592 QHHGLVEFVNPLAAHVAQLQLNGANLLGDCGTMRIDFSKNPGPLQVQRQSDKVRDYLESP 771
Q L+++ +P++A A+L L+G N+ C T+RIDFSK L V+ +DK RDY
Sbjct: 221 QFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTS-LNVKYNNDKSRDYTRPD 279
Query: 772 LTRNEMQ 792
L + Q
Sbjct: 280 LPSGDSQ 286
Score = 34.3 bits (77), Expect = 0.45
Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Frame = +1
Query: 127 PSRVIHIRNVPQEVDDTAVAML-AVPFGYIDNIVFVRKNNQ-ALIQMREISEAID-MADY 297
PS +H+ N+P V + + +L + G + F +K+ + ALIQM + EA+ + D
Sbjct: 452 PSATLHLSNIPPSVSEEDLKVLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIDL 511
Query: 298 FNQCVPLMYGKHLFIQFSK 354
N L HL + FSK
Sbjct: 512 HNH--DLGENHHLRVSFSK 528
Score = 32.7 bits (73), Expect = 1.3
Identities = 41/188 (21%), Positives = 80/188 (42%), Gaps = 3/188 (1%)
Frame = +1
Query: 157 PQEVDDTAVAMLAVPFGYIDNI-VFVRKNNQALIQMREISEAIDMADYFNQCVPLMYGKH 333
P+ V ++ +L +G + + + K AL+QM + ++A + N ++GK
Sbjct: 346 PERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGNQAQLAMSHLNG--HKLHGKP 403
Query: 334 LFIQFSKHQQLDLRNNNSNIDKLVQ-HANEKRKHYLVNWSNNTGGASEILRIL-IDNAPN 507
+ I SKHQ + L L + + N + S N L + N P
Sbjct: 404 IRITLSKHQNVQLpreGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPP 463
Query: 508 LVINHLVFYKIFSRFGQIIRIVSFTKNNQHHGLVEFVNPLAAHVAQLQLNGANLLGDCGT 687
V + +FS G +++ F + ++ L++ + A A + L+ + LG+
Sbjct: 464 SV-SEEDLKVLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIDLHNHD-LGENHH 521
Query: 688 MRIDFSKN 711
+R+ FSK+
Sbjct: 522 LRVSFSKS 529
>sp|P17225|PTBP1_MOUSE Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I)
Length = 527
Score = 149 bits (376), Expect = 1e-35
Identities = 86/247 (34%), Positives = 136/247 (55%), Gaps = 10/247 (4%)
Frame = +1
Query: 82 NSHKKVKMDQGNDNKPSRVIHIRNVPQEVDDTAVAMLAVPFGYIDNIVFVRKNNQALIQM 261
N KK K D + PSRVIH+R +P +V + V L +PFG + N++ ++ NQA I+M
Sbjct: 41 NDSKKFKGDNRSAGVPSRVIHVRKLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEM 100
Query: 262 REISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQL--DLRNNNSNIDKLVQHANEKRKHY 435
A M +Y+ P++ G+ ++IQFS H++L D N +Q N +
Sbjct: 101 NTEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKELKTDSSPNQVRAQAALQAVNSVQSGN 160
Query: 436 L--------VNWSNNTGGASEILRILIDNAPNLVINHLVFYKIFSRFGQIIRIVSFTKNN 591
L V+ G S +LRI+++N + V ++IFS+FG +++I++FTKNN
Sbjct: 161 LALAASAAAVDAGMAMAGQSPVLRIIVENL-FYPVTLDVLHQIFSKFGTVLKIITFTKNN 219
Query: 592 QHHGLVEFVNPLAAHVAQLQLNGANLLGDCGTMRIDFSKNPGPLQVQRQSDKVRDYLESP 771
Q L+++ +P++A A+L L+G N+ C T+RIDFSK L V+ +DK RDY
Sbjct: 220 QFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTS-LNVKYNNDKSRDYTRPD 278
Query: 772 LTRNEMQ 792
L + Q
Sbjct: 279 LPSGDSQ 285
Score = 33.9 bits (76), Expect = 0.58
Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Frame = +1
Query: 127 PSRVIHIRNVPQEV-DDTAVAMLAVPFGYIDNIVFVRKNNQ-ALIQMREISEAID-MADY 297
PS +H+ N+P V +D ++ + G + F +K+ + ALIQM + EA+ + +
Sbjct: 448 PSATLHLSNIPPSVSEDDLKSLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIEL 507
Query: 298 FNQCVPLMYGKHLFIQFSK 354
N L HL + FSK
Sbjct: 508 HNH--DLGENHHLRVSFSK 524
>sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1)
Length = 521
Score = 139 bits (349), Expect = 1e-32
Identities = 84/251 (33%), Positives = 141/251 (56%), Gaps = 9/251 (3%)
Frame = +1
Query: 82 NSHKKVKMDQGNDNKPSRVIHIRNVPQEVDDTAVAMLAVPFGYIDNIVFVRKNNQALIQM 261
N KK K D+ + PSRV+H+R +P +V + + L +PFG + N++ ++ +QA ++M
Sbjct: 12 NDSKKFKRDRPPCS-PSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEM 70
Query: 262 REISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQLDLRN--NNSNIDKLVQHANEKRKHY 435
A+ M +Y+ P + + ++IQ+S H++L N N + +Q + +
Sbjct: 71 ASEEAAVTMVNYYTPITPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGS 130
Query: 436 LV--NWSNNTG----GASEILRILIDNAPNLVINHLVFYKIFSRFGQIIRIVSFTKNNQH 597
L +N G G S +LRI+I+N V V ++IFS+FG +++I++FTKNNQ
Sbjct: 131 LALSGGPSNEGTVLPGQSPVLRIIIENLFYPVTLE-VLHQIFSKFGTVLKIITFTKNNQF 189
Query: 598 HGLVEFVNPLAAHVAQLQLNGANLLGDCGTMRIDFSKNPGPLQVQRQSDKVRDYLESPLT 777
L+++ +P+ AH A++ L+G N+ C T+RIDFSK L V+ +DK RD+ L
Sbjct: 190 QALLQYADPVNAHYAKMALDGQNIYNACCTLRIDFSKLTS-LNVKYNNDKSRDFTRLDLP 248
Query: 778 RNEMQ-ELEGP 807
+ Q LE P
Sbjct: 249 TGDGQPSLEPP 259
Score = 31.6 bits (70), Expect = 2.9
Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 3/102 (2%)
Frame = +1
Query: 58 DFSQNSFDNSHKKVKMDQGNDNKPSRVIHIRNVPQEVDDTAVAMLAVPFG-YIDNIVFVR 234
DFS + K + N PS +H+ N+P V + L + G + F +
Sbjct: 419 DFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQ 478
Query: 235 KNNQ-ALIQMREISEAID-MADYFNQCVPLMYGKHLFIQFSK 354
K+ + ALIQ+ + EAI + + N L HL + FSK
Sbjct: 479 KDRKMALIQLGSVEEAIQALIELHNH--DLGENHHLRVSFSK 518
Score = 30.8 bits (68), Expect = 5.0
Identities = 38/169 (22%), Positives = 77/169 (45%), Gaps = 5/169 (2%)
Frame = +1
Query: 220 IVFVRKNNQALIQMREISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQLDLRNNNSNIDK 399
I+F +K N AL+QM + ++A ++ + +YGK L SKHQ + L
Sbjct: 359 IMFNKKEN-ALVQMADANQAQLAMNHLSG--QRLYGKVLRATLSKHQAVQLpreGQEDQG 415
Query: 400 LVQHANEKRKHYL-----VNWSNNTGGASEILRILIDNAPNLVINHLVFYKIFSRFGQII 564
L + + H N+ N ++ + L + P++ ++ L +F G +
Sbjct: 416 LTKDFSNSPLHRFKKPGSKNFQNIFPPSATL--HLSNIPPSVTVDDL--KNLFIEAGCSV 471
Query: 565 RIVSFTKNNQHHGLVEFVNPLAAHVAQLQLNGANLLGDCGTMRIDFSKN 711
+ F + ++ L++ + A A ++L+ + LG+ +R+ FSK+
Sbjct: 472 KAFKFFQKDRKMALIQLGSVEEAIQALIELHNHD-LGENHHLRVSFSKS 519
>sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1)
Length = 523
Score = 136 bits (343), Expect = 6e-32
Identities = 85/251 (33%), Positives = 139/251 (55%), Gaps = 19/251 (7%)
Frame = +1
Query: 112 GNDNK----------PSRVIHIRNVPQEVDDTAVAMLAVPFGYIDNIVFVRKNNQALIQM 261
GNDNK PSRV+H+R +P +V + V L +PFG + N++ ++ +QA ++M
Sbjct: 13 GNDNKKFKGDRPPCSPSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEM 72
Query: 262 REISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQLDLRN--NNSNIDKLVQ--HANEKRK 429
A+ M +Y+ P + + ++IQ+S H++L N N + +Q A +
Sbjct: 73 ASEEAAVTMINYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGN 132
Query: 430 HYLVNWSNNTG----GASEILRILIDNAPNLVINHLVFYKIFSRFGQIIRIVSFTKNNQH 597
L ++N G G S +LRI+I+N V V ++IFS+FG +++I++FTKNNQ
Sbjct: 133 LSLPGATSNEGTLLPGQSPVLRIIIENLFYPVTLE-VLHQIFSKFGTVLKIITFTKNNQF 191
Query: 598 HGLVEFVNPLAAHVAQLQLNGANLLGDCGTMRIDFSKNPGPLQVQRQSDKVRDYLESPLT 777
L+++ +P+ A A++ L+G N+ C T+RIDFSK L V+ +DK RD+ L
Sbjct: 192 QALLQYADPVNAQYAKMALDGQNIYNACCTLRIDFSKLTS-LNVKYNNDKSRDFTRLDLP 250
Query: 778 RNEMQ-ELEGP 807
+ Q LE P
Sbjct: 251 TGDGQPSLEPP 261
Score = 32.7 bits (73), Expect = 1.3
Identities = 39/169 (23%), Positives = 78/169 (46%), Gaps = 5/169 (2%)
Frame = +1
Query: 220 IVFVRKNNQALIQMREISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQLDLRNNNSNIDK 399
I+F +K N AL+QM + S+A ++ + +YGK L SKHQ + L
Sbjct: 361 IMFNKKEN-ALVQMADASQAQIAMNHLSG--QRLYGKVLRATLSKHQAVQLpreGQEDQG 417
Query: 400 LVQHANEKRKHYL-----VNWSNNTGGASEILRILIDNAPNLVINHLVFYKIFSRFGQII 564
L + + H N+ N ++ + L + P++ ++ L +F+ G +
Sbjct: 418 LTKDFSNSPLHRFKKPGSKNFQNIFPPSATL--HLSNIPPSVTMDDL--KNLFTEAGCSV 473
Query: 565 RIVSFTKNNQHHGLVEFVNPLAAHVAQLQLNGANLLGDCGTMRIDFSKN 711
+ F + ++ L++ + A A ++L+ + LG+ +R+ FSK+
Sbjct: 474 KAFKFFQKDRKMALIQLGSVEEAIQALIELHNHD-LGENHHLRVSFSKS 521
Score = 30.4 bits (67), Expect = 6.5
Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 3/102 (2%)
Frame = +1
Query: 58 DFSQNSFDNSHKKVKMDQGNDNKPSRVIHIRNVPQEVDDTAVAMLAVPFG-YIDNIVFVR 234
DFS + K + N PS +H+ N+P V + L G + F +
Sbjct: 421 DFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQ 480
Query: 235 KNNQ-ALIQMREISEAID-MADYFNQCVPLMYGKHLFIQFSK 354
K+ + ALIQ+ + EAI + + N L HL + FSK
Sbjct: 481 KDRKMALIQLGSVEEAIQALIELHNH--DLGENHHLRVSFSK 520
>sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1)
Length = 523
Score = 136 bits (342), Expect = 8e-32
Identities = 84/251 (33%), Positives = 134/251 (53%), Gaps = 19/251 (7%)
Frame = +1
Query: 112 GNDNK----------PSRVIHIRNVPQEVDDTAVAMLAVPFGYIDNIVFVRKNNQALIQM 261
GNDNK PSRV+H+R +P +V + V L +PFG + N++ ++ +QA ++M
Sbjct: 13 GNDNKKFKGDRPPCSPSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEM 72
Query: 262 REISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQLDLRN--NNSNID------KLVQHAN 417
A+ M +Y+ P + + ++IQ+S H++L N N + VQ N
Sbjct: 73 ASEEAAVTMINYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGN 132
Query: 418 EKRKHYLVNWSNNTGGASEILRILIDNAPNLVINHLVFYKIFSRFGQIIRIVSFTKNNQH 597
N G S +LRI+I+N V V ++IFS+FG +++I++FTKNNQ
Sbjct: 133 LSLPGATANEGTLLPGQSPVLRIIIENLFYPVTLE-VLHQIFSKFGTVLKIITFTKNNQF 191
Query: 598 HGLVEFVNPLAAHVAQLQLNGANLLGDCGTMRIDFSKNPGPLQVQRQSDKVRDYLESPLT 777
L+++ +P+ A A++ L+G N+ C T+RIDFSK L V+ +DK RD+ L
Sbjct: 192 QALLQYADPVNAQYAKMALDGQNIYNACCTLRIDFSKLTS-LNVKYNNDKSRDFTRLDLP 250
Query: 778 RNEMQ-ELEGP 807
+ Q LE P
Sbjct: 251 TGDGQPSLEPP 261
Score = 32.3 bits (72), Expect = 1.7
Identities = 39/169 (23%), Positives = 78/169 (46%), Gaps = 5/169 (2%)
Frame = +1
Query: 220 IVFVRKNNQALIQMREISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQLDLRNNNSNIDK 399
I+F +K N AL+QM + S+A ++ + +YGK L SKHQ + L
Sbjct: 361 IMFNKKEN-ALVQMADASQAQLAMNHLSG--QRLYGKVLRATLSKHQAVQLpreGQEDQG 417
Query: 400 LVQHANEKRKHYL-----VNWSNNTGGASEILRILIDNAPNLVINHLVFYKIFSRFGQII 564
L + + H N+ N ++ + L + P++ ++ L +F+ G +
Sbjct: 418 LTKDFSNSPLHRFKKPGSKNFQNIFPPSATL--HLSNIPPSVTMDDL--KNLFTEAGCSV 473
Query: 565 RIVSFTKNNQHHGLVEFVNPLAAHVAQLQLNGANLLGDCGTMRIDFSKN 711
+ F + ++ L++ + A A ++L+ + LG+ +R+ FSK+
Sbjct: 474 KAFKFFQKDRKMALIQLGSVEEAIQALIELHNHD-LGENHHLRVSFSKS 521
Score = 30.4 bits (67), Expect = 6.5
Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 3/102 (2%)
Frame = +1
Query: 58 DFSQNSFDNSHKKVKMDQGNDNKPSRVIHIRNVPQEVDDTAVAMLAVPFG-YIDNIVFVR 234
DFS + K + N PS +H+ N+P V + L G + F +
Sbjct: 421 DFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQ 480
Query: 235 KNNQ-ALIQMREISEAID-MADYFNQCVPLMYGKHLFIQFSK 354
K+ + ALIQ+ + EAI + + N L HL + FSK
Sbjct: 481 KDRKMALIQLGSVEEAIQALIELHNH--DLGENHHLRVSFSK 520
>sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprotein L-like (Stromal
RNA-regulating factor) (BLOCK24 protein)
Length = 542
Score = 68.2 bits (165), Expect = 3e-11
Identities = 60/242 (24%), Positives = 105/242 (43%)
Frame = +1
Query: 61 FSQNSFDNSHKKVKMDQGNDNKPSRVIHIRNVPQEVDDTAVAMLAVPFGYIDNIVFVRKN 240
FSQ SH KV + S V+H+R + + V + + FG I ++ +
Sbjct: 60 FSQPEAGGSHHKVSV--------SPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFK 111
Query: 241 NQALIQMREISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQLDLRNNNSNIDKLVQHANE 420
QAL++ I A + + + G+ F +S +++ N
Sbjct: 112 RQALVEFENIDSAKECVTFAADEPVYIAGQQAFFNYSTSKRITRPGN------------- 158
Query: 421 KRKHYLVNWSNNTGGASEILRILIDNAPNLVINHLVFYKIFSRFGQIIRIVSFTKNNQHH 600
+++ G +++L + I N P I V Y + + G++ RIV F K N
Sbjct: 159 ---------TDDPSGGNKVLLLSIQN-PLYPITVDVLYTVCNPVGKVQRIVIF-KRNGIQ 207
Query: 601 GLVEFVNPLAAHVAQLQLNGANLLGDCGTMRIDFSKNPGPLQVQRQSDKVRDYLESPLTR 780
+VEF + L A A+ LNGA++ C T++I++++ P L V R + DY + L R
Sbjct: 208 AMVEFESVLCAQKAKAALNGADIYAGCCTLKIEYAR-PTRLNVIRNDNDSWDYTKPYLGR 266
Query: 781 NE 786
+
Sbjct: 267 RD 268
>sp|Q921F4|HNRLL_MOUSE Heterogeneous nuclear ribonucleoprotein L-like
Length = 591
Score = 65.5 bits (158), Expect = 2e-10
Identities = 57/234 (24%), Positives = 102/234 (43%)
Frame = +1
Query: 85 SHKKVKMDQGNDNKPSRVIHIRNVPQEVDDTAVAMLAVPFGYIDNIVFVRKNNQALIQMR 264
SH KV + S V+H+R + + V + + FG I ++ + QAL++
Sbjct: 117 SHHKVSV--------SPVVHVRGLCESVVEADLVEALEKFGTICYVMMMPFKRQALVEFE 168
Query: 265 EISEAIDMADYFNQCVPLMYGKHLFIQFSKHQQLDLRNNNSNIDKLVQHANEKRKHYLVN 444
I A + + + G+ F +S +++ N
Sbjct: 169 NIDSAKECVTFAADVPVYIAGQQAFFNYSTSKRITRPGN--------------------- 207
Query: 445 WSNNTGGASEILRILIDNAPNLVINHLVFYKIFSRFGQIIRIVSFTKNNQHHGLVEFVNP 624
+++ G +++L + I N P I V Y + + G++ RIV F K N +VEF +
Sbjct: 208 -TDDPSGGNKVLLLSIQN-PLYPITVDVLYTVCNPVGKVQRIVIF-KRNGIQAMVEFESV 264
Query: 625 LAAHVAQLQLNGANLLGDCGTMRIDFSKNPGPLQVQRQSDKVRDYLESPLTRNE 786
L A A+ LNGA++ C T++I++++ P L V R + DY + L R +
Sbjct: 265 LCAQKAKAALNGADIYAGCCTLKIEYAR-PTRLNVIRNDNDSWDYTKPYLGRRD 317
>sp|Q8R081|HNRPL_MOUSE Heterogeneous nuclear ribonucleoprotein L (hnRNP L)
Length = 555
Score = 62.4 bits (150), Expect = 2e-09
Identities = 56/224 (25%), Positives = 95/224 (42%)
Frame = +1
Query: 106 DQGNDNKPSRVIHIRNVPQEVDDTAVAMLAVPFGYIDNIVFVRKNNQALIQMREISEAID 285
D + S V+HIR + V + + FG I +V + K QAL++ ++ A +
Sbjct: 59 DDPHKTPASPVVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACN 118
Query: 286 MADYFNQCVPLMYGKHLFIQFSKHQQLDLRNNNSNIDKLVQHANEKRKHYLVNWSNNTGG 465
+Y + G F+ +S Q++ + S+++
Sbjct: 119 AVNYAADNQIYIAGHPAFVNYSTSQKISRPGD----------------------SDDSRS 156
Query: 466 ASEILRILIDNAPNLVINHLVFYKIFSRFGQIIRIVSFTKNNQHHGLVEFVNPLAAHVAQ 645
+ +L I N P I V Y I + G + RIV F KN +VEF + +A A+
Sbjct: 157 VNSVLLFTILN-PIYSITTDVLYTICNPCGPVQRIVIFRKNGV-QAMVEFDSVQSAQRAK 214
Query: 646 LQLNGANLLGDCGTMRIDFSKNPGPLQVQRQSDKVRDYLESPLT 777
LNGA++ C T++I+++K P L V + DY L+
Sbjct: 215 ASLNGADIYSGCCTLKIEYAK-PTRLNVFKNDQDTWDYTNPNLS 257
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 97,104,199
Number of Sequences: 369166
Number of extensions: 1996192
Number of successful extensions: 5380
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5163
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5367
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8341863645
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)