Planaria EST Database

DrC_00819

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00819
         (1077 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q99683|M3K5_HUMAN  Mitogen-activated protein kinase kinas...   109   1e-23
sp|Q05397|FAK1_HUMAN  Focal adhesion kinase 1 (FADK 1) (pp12...   106   1e-22
sp|O35346|FAK1_RAT  Focal adhesion kinase 1 (FADK 1) (pp125FAK)   106   1e-22
sp|P34152|FAK1_MOUSE  Focal adhesion kinase 1 (FADK 1) (pp12...   106   1e-22
sp|Q91738|FAK1_XENLA  Focal adhesion kinase 1 (FADK 1) (pp12...   105   3e-22
sp|Q00944|FAK1_CHICK  Focal adhesion kinase 1 (FADK 1) (PP12...   103   1e-21
sp|Q9Y7J6|KOIA_SCHPO  Putative serine/threonine-protein kina...   103   1e-21
sp|P42687|SPK1_DUGTI  Tyrosine-protein kinase SPK-1               102   2e-21
sp|Q9SZ67|WRK19_ARATH  Probable WRKY transcription factor 19...   101   4e-21
sp|Q12236|KOK0_YEAST  Probable serine/threonine-protein kina...   100   5e-21

>sp|Q99683|M3K5_HUMAN Mitogen-activated protein kinase kinase kinase 5 (MAPK/ERK kinase
            kinase 5) (MEK kinase 5) (MEKK 5) (Apoptosis
            signal-regulating kinase 1) (ASK-1)
          Length = 1374

 Score =  109 bits (273), Expect = 1e-23
 Identities = 74/258 (28%), Positives = 127/258 (49%), Gaps = 7/258 (2%)
 Frame = +2

Query: 266  KGNFSELKRGTFKNTNTEILIRKYEVKSSKTWKDEEFMLKELITFQMTKSHRRFIQLLGV 445
            KG +  +  G   +    I I++   + S+  +     L E I       H+  +Q LG 
Sbjct: 688  KGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQP----LHEEIALHKHLKHKNIVQYLGS 743

Query: 446  YIDDAILYVVMENMDRGTLKTFLQENYKNLDKNK--IYKWSAQILEGLKFLHENKVIHRD 619
            + ++  + + ME +  G+L   L+  +  L  N+  I  ++ QILEGLK+LH+N+++HRD
Sbjct: 744  FSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRD 803

Query: 620  LNPSSILVDGNED-LKLSSFNLSKYL-DISKAPASIMGKHDKKKELPLRYMAPEILNSD- 790
            +   ++L++     LK+S F  SK L  I+    +  G         L+YMAPEI++   
Sbjct: 804  IKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTG--------TLQYMAPEIIDKGP 855

Query: 791  -NYGEACDVWSFGAVLIRITTNKKPYSNLNKSEALDHISKLKMIEYKLPNKYS-EFKSII 964
              YG+A D+WS G  +I + T K P+  L + +A      +  +  ++P   S E K+ I
Sbjct: 856  RGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFI 915

Query: 965  NLCLQQDPSWRGKVKELI 1018
              C + DP  R    +L+
Sbjct: 916  LKCFEPDPDKRACANDLL 933

>sp|Q05397|FAK1_HUMAN Focal adhesion kinase 1 (FADK 1) (pp125FAK) (Protein-tyrosine kinase
            2)
          Length = 1052

 Score =  106 bits (264), Expect = 1e-22
 Identities = 69/263 (26%), Positives = 132/263 (50%), Gaps = 2/263 (0%)
 Frame = +2

Query: 260  ITKGNFSELKRGTFKNT-NTEILIRKYEVKSSKTWKDEEFMLKELITFQMTKSHRRFIQL 436
            I +G F ++ +G + +  N  + +     K+  +    E  L+E +T +    H   ++L
Sbjct: 428  IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQF-DHPHIVKL 486

Query: 437  LGVYIDDAILYVVMENMDRGTLKTFLQENYKNLDKNKIYKWSAQILEGLKFLHENKVIHR 616
            +GV  ++ + +++ME    G L++FLQ    +LD   +  ++ Q+   L +L   + +HR
Sbjct: 487  IGVITENPV-WIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHR 545

Query: 617  DLNPSSILVDGNEDLKLSSFNLSKYLDISKAPASIMGKHDKKKELPLRYMAPEILNSDNY 796
            D+   ++LV  N+ +KL  F LS+Y++ S    +  GK      LP+++MAPE +N   +
Sbjct: 546  DIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGK------LPIKWMAPESINFRRF 599

Query: 797  GEACDVWSFGAVLIRITTN-KKPYSNLNKSEALDHISKLKMIEYKLPNKYSEFKSIINLC 973
              A DVW FG  +  I  +  KP+  +  ++ +  I   + +    PN      S++  C
Sbjct: 600  TSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMP-PNCPPTLYSLMTKC 658

Query: 974  LQQDPSWRGKVKELIEKINNVLK 1042
               DPS R +  EL  +++ +L+
Sbjct: 659  WAYDPSRRPRFTELKAQLSTILE 681

>sp|O35346|FAK1_RAT Focal adhesion kinase 1 (FADK 1) (pp125FAK)
          Length = 1055

 Score =  106 bits (264), Expect = 1e-22
 Identities = 69/263 (26%), Positives = 132/263 (50%), Gaps = 2/263 (0%)
 Frame = +2

Query: 260  ITKGNFSELKRGTFKNT-NTEILIRKYEVKSSKTWKDEEFMLKELITFQMTKSHRRFIQL 436
            I +G F ++ +G + +  N  + +     K+  +    E  L+E +T +    H   ++L
Sbjct: 428  IGEGQFGDVHQGVYLSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQF-DHPHIVKL 486

Query: 437  LGVYIDDAILYVVMENMDRGTLKTFLQENYKNLDKNKIYKWSAQILEGLKFLHENKVIHR 616
            +GV  ++ + +++ME    G L++FLQ    +LD   +  ++ Q+   L +L   + +HR
Sbjct: 487  IGVITENPV-WIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHR 545

Query: 617  DLNPSSILVDGNEDLKLSSFNLSKYLDISKAPASIMGKHDKKKELPLRYMAPEILNSDNY 796
            D+   ++LV  N+ +KL  F LS+Y++ S    +  GK      LP+++MAPE +N   +
Sbjct: 546  DIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGK------LPIKWMAPESINFRRF 599

Query: 797  GEACDVWSFGAVLIRITTN-KKPYSNLNKSEALDHISKLKMIEYKLPNKYSEFKSIINLC 973
              A DVW FG  +  I  +  KP+  +  ++ +  I   + +    PN      S++  C
Sbjct: 600  TSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMP-PNCPPTLYSLMTKC 658

Query: 974  LQQDPSWRGKVKELIEKINNVLK 1042
               DPS R +  EL  +++ +L+
Sbjct: 659  WAYDPSRRPRFTELKAQLSTILE 681

>sp|P34152|FAK1_MOUSE Focal adhesion kinase 1 (FADK 1) (pp125FAK)
          Length = 1090

 Score =  106 bits (264), Expect = 1e-22
 Identities = 69/263 (26%), Positives = 132/263 (50%), Gaps = 2/263 (0%)
 Frame = +2

Query: 260  ITKGNFSELKRGTFKNT-NTEILIRKYEVKSSKTWKDEEFMLKELITFQMTKSHRRFIQL 436
            I +G F ++ +G + +  N  + +     K+  +    E  L+E +T +    H   ++L
Sbjct: 466  IGEGQFGDVHQGVYLSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQF-DHPHIVKL 524

Query: 437  LGVYIDDAILYVVMENMDRGTLKTFLQENYKNLDKNKIYKWSAQILEGLKFLHENKVIHR 616
            +GV  ++ + +++ME    G L++FLQ    +LD   +  ++ Q+   L +L   + +HR
Sbjct: 525  IGVITENPV-WIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHR 583

Query: 617  DLNPSSILVDGNEDLKLSSFNLSKYLDISKAPASIMGKHDKKKELPLRYMAPEILNSDNY 796
            D+   ++LV  N+ +KL  F LS+Y++ S    +  GK      LP+++MAPE +N   +
Sbjct: 584  DIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGK------LPIKWMAPESINFRRF 637

Query: 797  GEACDVWSFGAVLIRITTN-KKPYSNLNKSEALDHISKLKMIEYKLPNKYSEFKSIINLC 973
              A DVW FG  +  I  +  KP+  +  ++ +  I   + +    PN      S++  C
Sbjct: 638  TSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMP-PNCPPTLYSLMTKC 696

Query: 974  LQQDPSWRGKVKELIEKINNVLK 1042
               DPS R +  EL  +++ +L+
Sbjct: 697  WAYDPSRRPRFTELKAQLSTILE 719

>sp|Q91738|FAK1_XENLA Focal adhesion kinase 1 (FADK 1) (pp125FAK)
          Length = 1068

 Score =  105 bits (261), Expect = 3e-22
 Identities = 69/263 (26%), Positives = 131/263 (49%), Gaps = 2/263 (0%)
 Frame = +2

Query: 260  ITKGNFSELKRGTFKNT-NTEILIRKYEVKSSKTWKDEEFMLKELITFQMTKSHRRFIQL 436
            I +G F ++ +G + +  N  + +     K+  +    E  L+E +T +    H   ++L
Sbjct: 441  IGEGQFGDVHQGVYMSPENPAMAVAIKTCKNCTSDSVREKFLQEALTMRQF-DHPHIVKL 499

Query: 437  LGVYIDDAILYVVMENMDRGTLKTFLQENYKNLDKNKIYKWSAQILEGLKFLHENKVIHR 616
            +GV  ++ + +++ME    G L++FLQ    +LD   +  +S Q+   L +L   + +HR
Sbjct: 500  IGVITENPV-WIIMELCTLGELRSFLQVRKYSLDLASLILYSYQLSTALAYLESKRFVHR 558

Query: 617  DLNPSSILVDGNEDLKLSSFNLSKYLDISKAPASIMGKHDKKKELPLRYMAPEILNSDNY 796
            D+   ++LV  ++ +KL  F LS+Y++ S    +  GK      LP+++MAPE +N   +
Sbjct: 559  DIAARNVLVSSSDCVKLGDFGLSRYMEDSTYYKASKGK------LPIKWMAPESINFRRF 612

Query: 797  GEACDVWSFGAVLIRITT-NKKPYSNLNKSEALDHISKLKMIEYKLPNKYSEFKSIINLC 973
              A DVW FG  +  I     KP+  +  ++ +  I   + +    PN      S++  C
Sbjct: 613  TSASDVWMFGVCMWEILMYGVKPFQGVKNNDVIGRIENGERLPMP-PNCPPTLYSLMTKC 671

Query: 974  LQQDPSWRGKVKELIEKINNVLK 1042
               DPS R +  EL  +++ +L+
Sbjct: 672  WAYDPSRRPRFTELKAQLSTILE 694

>sp|Q00944|FAK1_CHICK Focal adhesion kinase 1 (FADK 1) (PP125FAK)
          Length = 1053

 Score =  103 bits (256), Expect = 1e-21
 Identities = 68/263 (25%), Positives = 131/263 (49%), Gaps = 2/263 (0%)
 Frame = +2

Query: 260  ITKGNFSELKRGTFKNT-NTEILIRKYEVKSSKTWKDEEFMLKELITFQMTKSHRRFIQL 436
            I +G F ++ +G + +  N  + +     K+  +    E  L+E +T +    H   ++L
Sbjct: 428  IGEGQFGDVHQGIYMSPENPAMAVAIKTCKNCTSDSVREKFLQEALTMRQF-DHPHIVKL 486

Query: 437  LGVYIDDAILYVVMENMDRGTLKTFLQENYKNLDKNKIYKWSAQILEGLKFLHENKVIHR 616
            +GV  ++ + +++ME    G L++FLQ    +LD   +  ++ Q+   L +L   + +HR
Sbjct: 487  IGVITENPV-WIIMELCTLGELRSFLQVRKFSLDLASLILYAYQLSTALAYLESKRFVHR 545

Query: 617  DLNPSSILVDGNEDLKLSSFNLSKYLDISKAPASIMGKHDKKKELPLRYMAPEILNSDNY 796
            D+   ++LV   + +KL  F LS+Y++ S    +  GK      LP+++MAPE +N   +
Sbjct: 546  DIAARNVLVSATDCVKLGDFGLSRYMEDSTYYKASKGK------LPIKWMAPESINFRRF 599

Query: 797  GEACDVWSFGAVLIRITTN-KKPYSNLNKSEALDHISKLKMIEYKLPNKYSEFKSIINLC 973
              A DVW FG  +  I  +  KP+  +  ++ +  I   + +    PN      S++  C
Sbjct: 600  TSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMP-PNCPPTLYSLMTKC 658

Query: 974  LQQDPSWRGKVKELIEKINNVLK 1042
               DPS R +  EL  +++ +L+
Sbjct: 659  WAYDPSRRPRFTELKAQLSTILE 681

>sp|Q9Y7J6|KOIA_SCHPO Putative serine/threonine-protein kinase C1778.10c
          Length = 550

 Score =  103 bits (256), Expect = 1e-21
 Identities = 68/239 (28%), Positives = 122/239 (51%), Gaps = 12/239 (5%)
 Frame = +2

Query: 254 DYITKGNFSELKRGTFKNTNTE----ILIRKYEVKSSKTWKDEEFMLKELITFQMTKSHR 421
           D I  G+FS+++R T K +  E    +L +KY VK +K     +++  E  +        
Sbjct: 58  DIIGDGSFSKVRRATDKKSWKEYAIKVLDKKYIVKENKV----KYVNIERDSMMRLNGFP 113

Query: 422 RFIQLLGVYIDDAILYVVMENMDRGTLKTFLQENYKNLDKNKIYKWSAQILEGLKFLHEN 601
              +L   + DD  LY V+E    G L  ++++ Y+ LD+N +  ++A+IL  ++++H  
Sbjct: 114 GISRLFHTFQDDLKLYYVLELAPNGELLQYIKK-YRFLDENCVRFYAAEILSSIEYMHSC 172

Query: 602 KVIHRDLNPSSILVDGNEDLKLSSFNLSKYL--------DISKAPASIMGKHDKKKELPL 757
            +IHRDL P +IL DGN  +K++ F  +K L        D +  P+S +G  +       
Sbjct: 173 GIIHRDLKPENILFDGNMHVKITDFGTAKILPPKYVNSPDYTTFPSSFVGTAE------- 225

Query: 758 RYMAPEILNSDNYGEACDVWSFGAVLIRITTNKKPYSNLNKSEALDHISKLKMIEYKLP 934
            Y+APE+L+     ++ D+W+F  V+ ++     P+   N +       K+  +EY+LP
Sbjct: 226 -YVAPELLSRQVVSKSSDLWAFACVVYQMIVGSPPFHGSNPNNI---FKKIMSLEYELP 280

>sp|P42687|SPK1_DUGTI Tyrosine-protein kinase SPK-1
          Length = 497

 Score =  102 bits (254), Expect = 2e-21
 Identities = 84/286 (29%), Positives = 141/286 (49%), Gaps = 22/286 (7%)
 Frame = +2

Query: 239  INMNDDYITKGNF---SELKRGTFKNTNTEILIRKYEV-----KSSKTWKDEEFMLKELI 394
            ++  D  I + N    +E+ RG F + +     R YEV     +SSK  + E+F+L+  I
Sbjct: 208  VHFQDIEINRENIEILNEIGRGFFGSVHRAKWGRSYEVAAKMLQSSKAER-EKFVLEAKI 266

Query: 395  TFQMTKSHRRFIQLLGVYID--DAILYVVMENMDRGTLKTFLQE-NYKNLDKNKIYKWSA 565
              ++   HR+ ++LLGV  +  D  + +++E M  G+LK +L+  + K  + N++    A
Sbjct: 267  MHKLR--HRKIVELLGVCTEPQDMPMLIIVEYMKNGSLKEYLKTPDGKKTNLNQMVHMMA 324

Query: 566  QILEGLKFLHENKVIHRDLNPSSILVDGNEDLKLSSFNLSKYLDISKAPASIMGKHDKKK 745
            +I EG+ +L   KV+HRDL   +ILV  +   K++ F L++  D S      +G  +KK 
Sbjct: 325  EISEGMAYLESEKVVHRDLRADNILVANDLTRKVADFGLTELTDGS------LGDQEKKT 378

Query: 746  -ELPLRYMAPEILNSDNYGEACDVWSFGAVLIRITT-NKKPYSNLNKSEALDHISKLKMI 919
               P ++ APE   S  +    DVWS+G V+  I T    PY ++   E ++ +SK    
Sbjct: 379  LRFPYKWTAPEAAKSKVFTSKSDVWSYGIVMFEILTWASSPYPDIPAKEVIEKVSK---- 434

Query: 920  EYKLPNKY---------SEFKSIINLCLQQDPSWRGKVKELIEKIN 1030
             Y++PN            E   I+  C   +P  R     L EK++
Sbjct: 435  GYRMPNPEKFITGVCCPDEIYKIMIWCWDANPEKRPTFLVLQEKMD 480

>sp|Q9SZ67|WRK19_ARATH Probable WRKY transcription factor 19 (WRKY DNA-binding protein 19)
          Length = 1895

 Score =  101 bits (251), Expect = 4e-21
 Identities = 62/206 (30%), Positives = 110/206 (53%), Gaps = 5/206 (2%)
 Frame = +2

Query: 416  HRRFIQLLGVYIDDAILYVVMENMDRGTLKTFLQENYKNLDKNKIYKWSAQILEGLKFLH 595
            H+  ++  G   D++ LY+ +E + +G+L+   Q N   L  + +  ++ QIL+GLK+LH
Sbjct: 1684 HQNIVRYRGTTKDESNLYIFLELVTQGSLRKLYQRN--QLGDSVVSLYTRQILDGLKYLH 1741

Query: 596  ENKVIHRDLNPSSILVDGNEDLKLSSFNLSKYLDISKAPASIMGKHDKKKELPLRYMAPE 775
            +   IHR++  +++LVD N  +KL+ F L+K + + + P                +MAPE
Sbjct: 1742 DKGFIHRNIKCANVLVDANGTVKLADFGLAKVMSLWRTPY-------------WNWMAPE 1788

Query: 776  IL----NSDNYGEACDVWSFGAVLIRITTNKKPYSNLNKSEALDHISKLKMIEYKLPNKY 943
            ++    + D YG   D+WS G  ++ + T + PYS+L    AL +I   K+   K+P+  
Sbjct: 1789 VILNPKDYDGYGTPADIWSLGCTVLEMLTGQIPYSDLEIGTALYNIGTGKL--PKIPDIL 1846

Query: 944  S-EFKSIINLCLQQDPSWRGKVKELI 1018
            S + +  I  CL+ +P  R    EL+
Sbjct: 1847 SLDARDFILTCLKVNPEERPTAAELL 1872

>sp|Q12236|KOK0_YEAST Probable serine/threonine-protein kinase YOL100W
          Length = 1081

 Score =  100 bits (250), Expect = 5e-21
 Identities = 67/252 (26%), Positives = 119/252 (47%), Gaps = 5/252 (1%)
 Frame = +2

Query: 287  KRGTFKNTNTEILIRKYEVKSSKTWKDEEFMLKELITFQMTKSHRRFIQLLGVYIDDAIL 466
            KR   K  N E LIR+ +VK         ++  E    Q   +    ++L   + D++ L
Sbjct: 203  KRYAAKVLNKEYLIRQKKVK---------YVSIEKTALQKLNNSPSVVRLFSTFQDESSL 253

Query: 467  YVVMENMDRGTLKTFLQENYKNLDKNKIYKWSAQILEGLKFLHENKVIHRDLNPSSILVD 646
            Y ++E    G   + L + Y +LD+     ++AQI++ + +LH N +IHRD+ P +IL+D
Sbjct: 254  YFLLEYAPNGDFLS-LMKKYGSLDETCARYYAAQIIDAIDYLHSNGIIHRDIKPENILLD 312

Query: 647  GNEDLKLSSFNLSKYLD-----ISKAPASIMGKHDKKKELPLRYMAPEILNSDNYGEACD 811
            G   +KL+ F  +K L+     +SK P   +    K       Y++PE+LN       CD
Sbjct: 313  GEMKIKLTDFGTAKLLNPTNNSVSK-PEYDLSTRSKSFVGTAEYVSPELLNDSFTDYRCD 371

Query: 812  VWSFGAVLIRITTNKKPYSNLNKSEALDHISKLKMIEYKLPNKYSEFKSIINLCLQQDPS 991
            +W+FG +L ++   K P                    +K  N+Y  F+ ++ +     P 
Sbjct: 372  IWAFGCILFQMIAGKPP--------------------FKATNEYLTFQKVMKVQYAFTPG 411

Query: 992  WRGKVKELIEKI 1027
            +   +++L++KI
Sbjct: 412  FPLIIRDLVKKI 423

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 114,151,312
Number of Sequences: 369166
Number of extensions: 2264598
Number of successful extensions: 9462
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 7496
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8004
length of database: 68,354,980
effective HSP length: 112
effective length of database: 47,664,660
effective search space used: 11725506360
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00819

  1. Dr_sW_020_O22
  2. Dr_sW_009_N24
  3. Dr_sW_011_C03