Planaria EST Database

DrC_00806

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00806
         (827 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|O70351|HCD2_RAT  3-hydroxyacyl-CoA dehydrogenase type II ...   258   1e-68
sp|O02691|HCD2_BOVIN  3-hydroxyacyl-CoA dehydrogenase type I...   254   2e-67
sp|O18404|HCD2_DROME  3-hydroxyacyl-CoA dehydrogenase type I...   253   6e-67
sp|Q99714|HCD2_HUMAN  3-hydroxyacyl-CoA dehydrogenase type I...   252   8e-67
sp|O08756|HCD2_MOUSE  3-hydroxyacyl-CoA dehydrogenase type I...   250   4e-66
sp|Q9X248|FABG_THEMA  3-oxoacyl-[acyl-carrier-protein] reduc...    95   3e-19
sp|P99120|BUTA_STAAN  Acetoin(diacetyl) reductase (Acetoin d...    90   9e-18
sp|P46331|YXBG_BACSU  Hypothetical oxidoreductase yxbG             86   2e-16
sp|P51831|FABG_BACSU  3-oxoacyl-[acyl-carrier-protein] reduc...    85   3e-16
sp|P66781|YD50_MYCTU  Putative oxidoreductase Rv1350/MT1393 ...    84   5e-16

>sp|O70351|HCD2_RAT 3-hydroxyacyl-CoA dehydrogenase type II (Type II HADH) (Endoplasmic
           reticulum-associated amyloid beta-peptide binding
           protein)
          Length = 261

 Score =  258 bits (660), Expect = 1e-68
 Identities = 126/236 (53%), Positives = 166/236 (70%), Gaps = 6/236 (2%)
 Frame = +2

Query: 77  TVERLTEQGCKVAICDIQ------EPKKLPANSYYIKTDVSCANDVENAITQIKSEAKKL 238
           T +RL  QG    + D+       E KKL  N  +   +V+   +V+ A+T  K +  ++
Sbjct: 26  TAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAALTLAKEKFGRI 85

Query: 239 DILVNCAGIGVAVKVYNRKKNSPHPLDTFERIVKVNAAGTFNMIRLCCSMFNSNEPNEFN 418
           D+ VNCAGI VA+K Y+ KKN  H L+ F+R++ VN  GTFN+IRL   +   NEP++  
Sbjct: 86  DVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGG 145

Query: 419 QRGIVINTSSIAAFEGQCGQSAYSASQGAIVAMTLPLARDLVAMGVRVMTIAPGIFLTPL 598
           QRG++INT+S+AAFEGQ GQ+AYSAS+G IV MTLP+ARDL  +G+RV+TIAPG+F TPL
Sbjct: 146 QRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPL 205

Query: 599 LENVPDSARLNLSKIVPFPSRLGHPDEFAHLVQSIIENPMLNGEVIRIDGALRMMP 766
           L  +PD  R  L+  VPFPSRLG P E+AHLVQ +IENP LNGEVIR+DGA+RM P
Sbjct: 206 LTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENPFLNGEVIRLDGAIRMQP 261

>sp|O02691|HCD2_BOVIN 3-hydroxyacyl-CoA dehydrogenase type II (Type II HADH)
          Length = 261

 Score =  254 bits (649), Expect = 2e-67
 Identities = 128/236 (54%), Positives = 164/236 (69%), Gaps = 6/236 (2%)
 Frame = +2

Query: 77  TVERLTEQGCKVAICDIQ------EPKKLPANSYYIKTDVSCANDVENAITQIKSEAKKL 238
           T ERL  QG    + D+       + KKL  +  +   DV+   DV+ A+T  + +  ++
Sbjct: 26  TAERLVGQGATAVLLDLPNSDGETQAKKLGKSCAFAPADVTSEKDVQAALTLAREKFGRV 85

Query: 239 DILVNCAGIGVAVKVYNRKKNSPHPLDTFERIVKVNAAGTFNMIRLCCSMFNSNEPNEFN 418
           D+ VNCAGI VA K YN KK+  H L+ F+R++ VN  GTFN+IRL       NEP++  
Sbjct: 86  DVAVNCAGIAVASKTYNLKKSQAHTLEDFQRVINVNLIGTFNVIRLVAGEMGQNEPDQGG 145

Query: 419 QRGIVINTSSIAAFEGQCGQSAYSASQGAIVAMTLPLARDLVAMGVRVMTIAPGIFLTPL 598
           QRG++INT+S+AAFEGQ GQ+AYSAS+G IV MTLP+ARDL  MG+RVMTIAPG+F TPL
Sbjct: 146 QRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPMGIRVMTIAPGLFGTPL 205

Query: 599 LENVPDSARLNLSKIVPFPSRLGHPDEFAHLVQSIIENPMLNGEVIRIDGALRMMP 766
           L  +PD  R  L+  VPFPSRLG P E+AHLVQ+IIEN  LNGEVIR+DGA+RM P
Sbjct: 206 LTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQAIIENSFLNGEVIRLDGAIRMQP 261

>sp|O18404|HCD2_DROME 3-hydroxyacyl-CoA dehydrogenase type II (Type II HADH) (Scully
           protein)
          Length = 255

 Score =  253 bits (645), Expect = 6e-67
 Identities = 121/236 (51%), Positives = 164/236 (69%), Gaps = 6/236 (2%)
 Frame = +2

Query: 77  TVERLTEQGCKVAICDI------QEPKKLPANSYYIKTDVSCANDVENAITQIKSEAKKL 238
           T ERL +QG  V + D+      +  K+L     ++  DV+   DV  A+   K +  +L
Sbjct: 20  TAERLAKQGASVILADLPSSKGNEVAKELGDKVVFVPVDVTSEKDVSAALQTAKDKFGRL 79

Query: 239 DILVNCAGIGVAVKVYNRKKNSPHPLDTFERIVKVNAAGTFNMIRLCCSMFNSNEPNEFN 418
           D+ VNCAG   AVK +N  KN  H L+ F+R++ +N  GTFN+IRL   +  +NEPN+  
Sbjct: 80  DLTVNCAGTATAVKTFNFNKNVAHRLEDFQRVININTVGTFNVIRLSAGLMGANEPNQDG 139

Query: 419 QRGIVINTSSIAAFEGQCGQSAYSASQGAIVAMTLPLARDLVAMGVRVMTIAPGIFLTPL 598
           QRG+++NT+S+AAF+GQ GQ+AYSAS+ A+V MTLP+ARDL   G+R+ TIAPG+F TP+
Sbjct: 140 QRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMTLPIARDLSTQGIRICTIAPGLFNTPM 199

Query: 599 LENVPDSARLNLSKIVPFPSRLGHPDEFAHLVQSIIENPMLNGEVIRIDGALRMMP 766
           L  +P+  R  L+K +PFP RLG P E+AHLVQ+I ENP+LNGEVIRIDGALRMMP
Sbjct: 200 LAALPEKVRTFLAKSIPFPQRLGEPSEYAHLVQAIYENPLLNGEVIRIDGALRMMP 255

>sp|Q99714|HCD2_HUMAN 3-hydroxyacyl-CoA dehydrogenase type II (Type II HADH) (Endoplasmic
           reticulum-associated amyloid beta-peptide binding
           protein) (Short-chain type dehydrogenase/reductase
           XH98G2)
          Length = 261

 Score =  252 bits (644), Expect = 8e-67
 Identities = 127/236 (53%), Positives = 163/236 (69%), Gaps = 6/236 (2%)
 Frame = +2

Query: 77  TVERLTEQGCKVAICDIQ------EPKKLPANSYYIKTDVSCANDVENAITQIKSEAKKL 238
           T ERL  QG    + D+       + KKL  N  +   DV+   DV+ A+   K +  ++
Sbjct: 26  TAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRV 85

Query: 239 DILVNCAGIGVAVKVYNRKKNSPHPLDTFERIVKVNAAGTFNMIRLCCSMFNSNEPNEFN 418
           D+ VNCAGI VA K YN KK   H L+ F+R++ VN  GTFN+IRL       NEP++  
Sbjct: 86  DVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGG 145

Query: 419 QRGIVINTSSIAAFEGQCGQSAYSASQGAIVAMTLPLARDLVAMGVRVMTIAPGIFLTPL 598
           QRG++INT+S+AAFEGQ GQ+AYSAS+G IV MTLP+ARDL  +G+RVMTIAPG+F TPL
Sbjct: 146 QRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPL 205

Query: 599 LENVPDSARLNLSKIVPFPSRLGHPDEFAHLVQSIIENPMLNGEVIRIDGALRMMP 766
           L ++P+     L+  VPFPSRLG P E+AHLVQ+IIENP LNGEVIR+DGA+RM P
Sbjct: 206 LTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENPFLNGEVIRLDGAIRMQP 261

>sp|O08756|HCD2_MOUSE 3-hydroxyacyl-CoA dehydrogenase type II (Type II HADH) (Endoplasmic
           reticulum-associated amyloid beta-peptide binding
           protein)
          Length = 261

 Score =  250 bits (638), Expect = 4e-66
 Identities = 122/236 (51%), Positives = 165/236 (69%), Gaps = 6/236 (2%)
 Frame = +2

Query: 77  TVERLTEQGCKVAICDI------QEPKKLPANSYYIKTDVSCANDVENAITQIKSEAKKL 238
           T +RL  QG    + D+       + KKL  +  +   +V+   +++ A+T  K +  ++
Sbjct: 26  TAKRLVGQGATAVLLDVPDSEGESQAKKLGESCIFAPANVTSEKEIQAALTLAKEKFGRI 85

Query: 239 DILVNCAGIGVAVKVYNRKKNSPHPLDTFERIVKVNAAGTFNMIRLCCSMFNSNEPNEFN 418
           D+ VNCAGI VA+K Y++KKN  H L+ F+R++ VN  GTFN+IRL       NEP++  
Sbjct: 86  DVAVNCAGIAVAIKTYHQKKNKIHTLEDFQRVINVNLIGTFNVIRLVAGEMGQNEPDQGG 145

Query: 419 QRGIVINTSSIAAFEGQCGQSAYSASQGAIVAMTLPLARDLVAMGVRVMTIAPGIFLTPL 598
           QRG++INT+S+AAFEGQ GQ+AYSAS+G I  MTLP+ARDL   G+RV+TIAPG+F TPL
Sbjct: 146 QRGVIINTASVAAFEGQVGQAAYSASKGGIDGMTLPIARDLAPTGIRVVTIAPGLFATPL 205

Query: 599 LENVPDSARLNLSKIVPFPSRLGHPDEFAHLVQSIIENPMLNGEVIRIDGALRMMP 766
           L  +P+  R  L+  VPFPSRLG P E+AHLVQ+IIENP LNGEVIR+DGA+RM P
Sbjct: 206 LTTLPEKVRNFLASQVPFPSRLGDPAEYAHLVQTIIENPFLNGEVIRLDGAIRMQP 261

>sp|Q9X248|FABG_THEMA 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier
           protein reductase)
          Length = 246

 Score = 94.7 bits (234), Expect = 3e-19
 Identities = 59/213 (27%), Positives = 107/213 (50%), Gaps = 3/213 (1%)
 Frame = +2

Query: 125 IQEPKKLPANSYYIKTDVSCANDVENAITQIKSEAKKLDILVNCAGIGVAVKVYNRKKNS 304
           ++E + LP        +V+  + ++  + ++  +  ++D+LVN AGI     +   K+  
Sbjct: 46  VKEAEGLPGKVDPYVLNVTDRDQIKEVVEKVVQKYGRIDVLVNNAGITRDALLVRMKE-- 103

Query: 305 PHPLDTFERIVKVNAAGTFNMIRLCCSMFNSNEPNEFNQR-GIVINTSSIAAFEGQCGQS 481
               + ++ ++ VN  G FN+ ++         P    QR G ++N SS+    G  GQ+
Sbjct: 104 ----EDWDAVINVNLKGVFNVTQMVV-------PYMIKQRNGSIVNVSSVVGIYGNPGQT 152

Query: 482 AYSASQGAIVAMTLPLARDLVAMGVRVMTIAPGIFLTPLLENVPDSARLNLSKIVPFPSR 661
            Y+AS+  ++ MT   A++L    +RV  +APG   TP+ E +P+ AR      +P   R
Sbjct: 153 NYAASKAGVIGMTKTWAKELAGRNIRVNAVAPGFIETPMTEKLPEKARETALSRIPL-GR 211

Query: 662 LGHPDEFAHLVQSII--ENPMLNGEVIRIDGAL 754
            G P+E A ++  +   E+  + G+VI IDG L
Sbjct: 212 FGKPEEVAQVILFLASDESSYVTGQVIGIDGGL 244

>sp|P99120|BUTA_STAAN Acetoin(diacetyl) reductase (Acetoin dehydrogenase) (AR)
           (Meso-2,3-butanediol dehydrogenase)
 sp|P66776|BUTA_STAAW Acetoin(diacetyl) reductase (Acetoin dehydrogenase) (AR)
           (Meso-2,3-butanediol dehydrogenase)
 sp|P66775|BUTA_STAAM Acetoin(diacetyl) reductase (Acetoin dehydrogenase) (AR)
           (Meso-2,3-butanediol dehydrogenase)
 sp|Q6GKH9|BUTA_STAAR Acetoin(diacetyl) reductase (Acetoin dehydrogenase) (AR)
           (Meso-2,3-butanediol dehydrogenase)
 sp|Q6GCZ8|BUTA_STAAS Acetoin(diacetyl) reductase (Acetoin dehydrogenase) (AR)
           (Meso-2,3-butanediol dehydrogenase)
          Length = 258

 Score = 89.7 bits (221), Expect = 9e-18
 Identities = 71/251 (28%), Positives = 114/251 (45%), Gaps = 26/251 (10%)
 Frame = +2

Query: 83  ERLTEQGCKVAICDIQEPKKLPA---------NSYYIKTDVSCANDVENAITQIKSEAKK 235
           ERL E G KVA+ D  E     A          +  IK DVS  +DV NA+ Q  ++   
Sbjct: 22  ERLVEDGFKVAVVDFNEEGAKAAALKLSSDGTKAIAIKADVSNRDDVFNAVRQTAAQFGD 81

Query: 236 LDILVNCAGIGVAVKVYNRKKNSPHPLDT-----FERIVKVNAAGTFNMIRLCCSMFNSN 400
             ++VN AG+G              P+DT     F+ +  VN AG    I+     F   
Sbjct: 82  FHVMVNNAGLGPTT-----------PIDTITEEQFKTVYGVNVAGVLWGIQAAHEQFK-- 128

Query: 401 EPNEFNQRGIVINTSSIAAFEGQCGQSAYSASQGAIVAMTLPLARDLVAMGVRVMTIAPG 580
              +FN  G +IN +S A  EG  G S Y +++ A+  +T   A+DL + G+ V   APG
Sbjct: 129 ---KFNHGGKIINATSQAGVEGNPGLSLYCSTKFAVRGLTQVAAQDLASEGITVNAFAPG 185

Query: 581 IFLTPLLENVPDSARLNLSKIVPFP----------SRLGHPDEFAHLVQSII--ENPMLN 724
           I  TP++E++  +      K   +            R+  P++ +++V  +   ++  + 
Sbjct: 186 IVQTPMMESIAVATAEEAGKPEAWGWEQFTSQIALGRVSQPEDVSNVVSFLAGKDSDYIT 245

Query: 725 GEVIRIDGALR 757
           G+ I +DG +R
Sbjct: 246 GQTIIVDGGMR 256

>sp|P46331|YXBG_BACSU Hypothetical oxidoreductase yxbG
          Length = 273

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 76/265 (28%), Positives = 114/265 (43%), Gaps = 19/265 (7%)
 Frame = +2

Query: 77  TVERLTEQGCKVAICDIQEP---------KKLPANSYYIKTDVSCANDVENAITQIKSEA 229
           T E    +G +V I DI +          +K    +     DVS  N V+    QIK   
Sbjct: 22  TAEVFANEGARVIIGDINKDQMEETVDAIRKNGGQAESFHLDVSDENSVKAFADQIKDAC 81

Query: 230 KKLDILVNCAGIGVAVKVYNRKKNSPHPLDTFERIVKVNAAGTFNMIRLCCSMFNSNEPN 409
             +DIL N AG+          K   +P+D F+RI+ V+  GTF      CS +    P 
Sbjct: 82  GTIDILFNNAGVD-----QEGGKVHEYPVDLFDRIIAVDLRGTF-----LCSKYLI--PL 129

Query: 410 EFNQRGIVINTSSIAAFEGQCGQSAYSASQGAIVAMTLPLARDLVAMGVRVMTIAPGIFL 589
                G +INTSS++       +S Y+A++G I  +T  +A D    G+RV +I+PG   
Sbjct: 130 MLENGGSIINTSSMSGRAADLDRSGYNAAKGGITNLTKAMAIDYARNGIRVNSISPGTIE 189

Query: 590 TPLLENVPDSARLNLSK--------IVPFPSRLGHPDEFAHLVQSII--ENPMLNGEVIR 739
           TPL++ +  +    + +        I P   RLG P E A +   +   ++  + GE I 
Sbjct: 190 TPLIDKLAGTKEQEMGEQFREANKWITPL-GRLGQPKEMATVALFLASDDSSYVTGEDIT 248

Query: 740 IDGALRMMP*LLFWYNKTCIRFKMK 814
            DG +        W  K  I  K K
Sbjct: 249 ADGGIMAYT----WPGKMLIEEKWK 269

>sp|P51831|FABG_BACSU 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier
           protein reductase)
          Length = 246

 Score = 84.7 bits (208), Expect = 3e-16
 Identities = 56/214 (26%), Positives = 98/214 (45%), Gaps = 2/214 (0%)
 Frame = +2

Query: 125 IQEPKKLPANSYYIKTDVSCANDVENAITQIKSEAKKLDILVNCAGIGVAVKVYNRKKNS 304
           + E K +   +  +K DVS   DV+N I +  S    +DILVN AGI     +   K+  
Sbjct: 46  VDEIKSMGRKAIAVKADVSNPEDVQNMIKETLSVFSTIDILVNNAGITRDNLIMRMKE-- 103

Query: 305 PHPLDTFERIVKVNAAGTFNMIRLCCSMFNSNEPNEFNQRGIVINTSSIAAFEGQCGQSA 484
               D ++ ++ +N  G FN  +               + G +IN SSI    G  GQ+ 
Sbjct: 104 ----DEWDDVININLKGVFNCTKAVTRQMMKQ------RSGRIINVSSIVGVSGNPGQAN 153

Query: 485 YSASQGAIVAMTLPLARDLVAMGVRVMTIAPGIFLTPLLENVPDSARLNLSKIVPFPSRL 664
           Y A++  ++ +T   A++L +  + V  IAPG   T + + +    +  + K +P  +R 
Sbjct: 154 YVAAKAGVIGLTKSSAKELASRNITVNAIAPGFISTDMTDKLAKDVQDEMLKQIPL-ARF 212

Query: 665 GHPDEFAHLVQSIIEN--PMLNGEVIRIDGALRM 760
           G P + + +V  +       + G+ + IDG + M
Sbjct: 213 GEPSDVSSVVTFLASEGARYMTGQTLHIDGGMVM 246

>sp|P66781|YD50_MYCTU Putative oxidoreductase Rv1350/MT1393
 sp|P66782|YD85_MYCBO Putative oxidoreductase Mb1385
          Length = 247

 Score = 84.0 bits (206), Expect = 5e-16
 Identities = 63/233 (27%), Positives = 113/233 (48%), Gaps = 11/233 (4%)
 Frame = +2

Query: 83  ERLTEQGCKVAICDIQ------EPKKLPAN--SYYIKTDVSCANDVENAITQIKSEAKKL 238
           +R   +G +V + D+         K+L  +  +  ++ DV+ A+DV+  I         L
Sbjct: 25  QRFVAEGARVVLGDVNLEATEVAAKRLGGDDVALAVRCDVTQADDVDILIRTAVERFGGL 84

Query: 239 DILVNCAGIGVAVKVYNRKKNSPHPLDTFERIVKVNAAGTFNMIRLCCSMFNSNEPNEFN 418
           D++VN AGI     +    +      + F++++ V+  GT+N  RL  ++    +     
Sbjct: 85  DVMVNNAGITRDATMRTMTE------EQFDQVIAVHLKGTWNGTRLAAAIMRERK----- 133

Query: 419 QRGIVINTSSIAAFEGQCGQSAYSASQGAIVAMTLPLARDLVAMGVRVMTIAPGIFLTPL 598
            RG ++N SS++   G  GQ+ YSA++  IV MT   A++L  +G+RV  IAPG+  + +
Sbjct: 134 -RGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAIAPGLIRSAM 192

Query: 599 LENVPDSARLNLSKIVPFP-SRLGHPDEFAHLVQSIIE--NPMLNGEVIRIDG 748
            E +P   R+   K+   P  R G P E A +   +    +  + G V+ + G
Sbjct: 193 TEAMPQ--RIWDQKLAEVPMGRAGEPSEVASVAVFLASDLSSYMTGTVLDVTG 243

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,981,557
Number of Sequences: 369166
Number of extensions: 1793805
Number of successful extensions: 5383
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5094
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5247
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8004331590
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00806

  1. Dr_sW_020_K23
  2. Dr_sW_007_P09
  3. Dr_sW_020_C18
  4. Dr_sW_007_C04